CN210243672U - Full-automatic immunofluorescence detection equipment - Google Patents
Full-automatic immunofluorescence detection equipment Download PDFInfo
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- CN210243672U CN210243672U CN201921048125.6U CN201921048125U CN210243672U CN 210243672 U CN210243672 U CN 210243672U CN 201921048125 U CN201921048125 U CN 201921048125U CN 210243672 U CN210243672 U CN 210243672U
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Abstract
The utility model provides a full-automatic immunofluorescence check out test set, the utility model relates to a medical treatment detection area, for providing the full-automatic fluorescence check out test set of the continuous application of sample, the utility model provides a following technical scheme: the detection equipment comprises a sample continuous loading and unloading system for continuously conveying samples, a sampling device positioned above the sample continuous loading and unloading system, and a detection device for detecting the samples; the continuous sample loading and unloading system comprises a first track, a sample rack and a second power guide rail, wherein the first track is annularly arranged on the outer side of the detection device, the sample rack is erected on the first track, the second power guide rail is connected with the sample rack through a connecting rod, and more than one sample bottle for containing a sample is placed in the sample rack; the sample injection device has the beneficial effects that uninterrupted sample injection, automatic sample injection, dilution, inspection, photo, analysis and the like can be realized.
Description
Technical Field
The utility model relates to a medical treatment detection area, concretely relates to full-automatic immunofluorescence check out test set.
Background
From the clinical and diagnostic point of view, the influence of autoimmune diseases is exponentially increased, and the detection of autoantibodies is not only an important index for diagnosing autoimmune diseases, but also has important roles in disease judgment, monitoring, prognosis and the like, and simultaneously, the role of autoantibodies in the occurrence and development of diseases is gradually clarified. The detection methods of autoantibodies are all based on antigen-antibody reactions. The clinical laboratory selects a proper detection method according to the characteristics of the autoantibody, the binding characteristics of the antigen antibody and particularly the requirements of clinical application. Indirect immunofluorescence is the standard method for autoantibody detection in clinical diagnostics. Indirect immunofluorescence is also a classical approach to the exploration of unknown autoantibodies, most of which were first discovered by indirect immunofluorescence.
At present, most laboratories for indirect fluorescence detection are still in the manual operation stage, namely the human eye interpretation stage. Laboratory workers are subjected to manual operation with high intensity every day, meanwhile, the accuracy of results does not depend on the specification of the operation, and also seriously depends on comprehensive knowledge and professional skills of film readers, and in addition, how to realize uninterrupted continuous sample adding is also a difficult problem in the field. Therefore, with the wide application of indirect immunofluorescence technology, the requirement for automation is more and more urgent.
SUMMERY OF THE UTILITY MODEL
In order to solve the above mentioned problem, the utility model provides a following technical scheme:
the detection equipment comprises a sample continuous loading and unloading system for continuously conveying samples, a sampling device and a detection device, wherein the sampling device is positioned above the sample continuous loading and unloading system and used for sampling, diluting and adding samples, and the detection device is used for detecting the samples; the continuous sample handling system comprises a first track arranged outside the detection device, a sample rack arranged on the first track, and a second power guide rail arranged at the bottom of the sample rack and used for driving the sample rack to run along the first track and supporting the sample rack, wherein the second power guide rail is connected with the sample rack through a connecting rod, and more than one sample bottle used for containing samples is placed in the sample rack; the first track is divided into a sample loading section track, a sample collecting section track and a sample recovering section track which are connected in sequence, wherein the sample collecting section track is respectively vertical to the sample loading section track and the sample recovering section track, the track inner width of the sample loading section track and the sample recovering section track is slightly larger than the length of the sample rack, and the track inner width of the sample collecting section track is slightly larger than the width of the sample rack.
Further, first track be the double track, sample frame four corners be equipped with respectively with four first card pins, second card pin, third card pin and the fourth card pin of using with the double track cooperation of institute.
Furthermore, the full-automatic immunofluorescence detection device further comprises a scanning device used for scanning the bar code of the sample bottle to read bar code information, and the scanning device is arranged at the joint of the sample loading section track and the sample collecting section track.
Furthermore, the sampling device comprises a sampling needle and a mechanical arm for driving the sampling needle to operate within a specified range; the detection device comprises a dilution cup for diluting a sample, a suction and discharge device for uniformly mixing the sample in the dilution cup and an acquisition system for acquiring a fluorescence photo of the diluted sample, wherein generally, the acquisition system comprises a glass slide for bearing the sample and a microscope for acquiring the fluorescence photo.
The beneficial effects of the utility model reside in that, the sample bottle that is equipped with the sample is put into the sample frame, the sample frame moves ahead through sample loading section track under the drive of second power guide rail, can set up a plurality of sample frames according to actual need on the sample loading section track in order to realize carrying the appearance in succession, the sample frame scans the collection information to the sample when getting into sample loading section track and sample acquisition section track handing-over department, get into sample acquisition section track after information acquisition finishes, the arm operation, the sampling needle inhales the appearance under the drive of arm, put the sample of absorbing into the dilution cup, inhale and spit the device and adopt the mode of inhaling one and spitting to accelerate the mixing of sample, the sample after the mixing adds in the reaction hole of slide glass, carry out operations such as incubation, fluorescence detection carries out after the operation is accomplished; and the sample rack sucked with the sample continues to move forwards along the sample collecting section track and then enters the sample recovering section track for recovering.
Drawings
Fig. 1 is a top view of the present invention;
fig. 2 is a cross-sectional view of the rail and the sample holder of the present invention.
Fig. 3 is a top view of the sample holder of the present invention.
Detailed Description
The invention will be further explained and explained with reference to the drawings.
Referring to fig. 1 to 3, a fully automatic immunofluorescence detection apparatus includes a sample continuous handling system for continuously transporting samples, a sampling device located above the sample continuous handling system for sampling, diluting and adding samples, and a detection device for detecting samples; the continuous sample handling system comprises a first track (1) arranged outside the detection device in an annular mode, a sample rack (2) arranged on the first track, and a second power guide rail (3) arranged at the bottom of the sample rack (2) and used for driving the sample rack to run along the first track (1) and supporting the sample rack, wherein the second power guide rail (3) is connected with the sample rack (2) through a connecting rod (31), and more than one sample bottle (21) used for containing a sample is placed in the sample rack (2); the first track (1) is divided into a sample loading section track (11), a sample collecting section track (12) and a sample recovering section track (13) which are sequentially connected, wherein the sample loading section track (11) is positioned in the right area of the instrument, the sample collecting section track (12) is positioned behind the instrument, and the sample recovering section track (13) is positioned in the left area of the instrument; the sample collection section track (12) is respectively perpendicular to the sample loading section track (11) and the sample recovery section track (13), as shown in fig. 1, the track inner width x of the sample loading section track (11) and the sample recovery section track (13) is slightly larger than the sample rack length y, the track inner width z of the sample collection section track (12) is slightly larger than the sample rack width y', a sample rack (2) transversely passes through the sample loading section track (11), is changed into a vertical passage after entering the sample collection section track (12), and is changed into a transverse passage again after reaching the sample recovery section track (13).
As shown in the figure, the first track (1) is a double track and comprises a left track (12) and a right track (13), four corners of the sample rack (2) are respectively provided with a first card pin (22), a second card pin (23), a third card pin (24) and a fourth card pin (25) which are matched with the four sample racks and the two tracks, when the sample rack (2) runs on the sample loading section track (11) and the sample recovery section track (13), a first card pin (22) and a second card pin (23) run on the left rail (12), a third card pin (24) and a fourth card pin (25) run on the right rail (13), when the sample rack (2) runs on the sample collection section track (12), the second card pin (23) and the third card pin (24) are in the left track (12), and the first card pin (22) and the fourth card pin (25) are in the right track (13).
The full-automatic immunofluorescence detection device further comprises a scanning device (4) used for scanning the bar codes of the sample bottles to read the bar code information, wherein the scanning device (4) is arranged at the joint of the sample loading section track (11) and the sample collecting section track (12), the bar code scanning is started, the bar code information of the sample rack and the sample is read, and then the sampling step is carried out.
The detection device comprises a dilution cup for diluting a sample, a suction and discharge device for uniformly mixing the sample in the dilution cup and an acquisition system for acquiring a fluorescence photo of the diluted sample, wherein generally, the acquisition system comprises a glass slide for bearing the sample and a microscope for acquiring the fluorescence photo.
The sampling device comprises a sampling needle and a mechanical arm for driving the sampling needle to operate within a specified range; the arm moves the top of the sample frame (2) of the sampling area that has scanned and has finished and be located on sample acquisition section track (12) with the sampling needle, sample to in the sample bottle is gathered, then send to the dilution cup, the sampling needle continues to absorb diluent or reagent and puts into the dilution cup, put into after the completion and inhale and tell the device and carry out the mixing operation, the reaction hole position of slide is added with the sample to the sample needle at last, incubate, use the washing needle of dress on the arm to wash after the completion of incubation, wash the completion back, use the sample needle to inhale the reaction hole that the sample added to the slide from the reagent area, incubate, reuse washing needle washes after the incubation is finished. After the above-mentioned work is accomplished, need use the sample needle to absorb the mounting agent from the reagent district and add to every reaction hole, use the grabhook to snatch the coverslip from the mounting container and put on every slide, then transfer the slide one by one to the microscope of collection system and carry out the fluorescence photo and gather, after shooing and obtaining multiple colour fluorescence image, can accomplish the analysis automatically through analysis software, output result report.
Claims (4)
1. The detection equipment comprises a sample continuous loading and unloading system for continuously conveying samples, a sampling device and a detection device, wherein the sampling device is positioned above the sample continuous loading and unloading system and used for sampling, diluting and adding samples, and the detection device is used for detecting the samples; the continuous sample handling system is characterized by comprising a first track, a sample rack and a second power guide rail, wherein the first track is arranged on the outer side of the detection device in an annular mode, the sample rack is erected on the first track, the second power guide rail is arranged at the bottom of the sample rack and used for driving the sample rack to run along the first track and supporting the sample rack, the second power guide rail is connected with the sample rack through a connecting rod, and more than one sample bottle for containing samples is placed in the sample rack; the first track is divided into a sample loading section track, a sample collecting section track and a sample recovering section track which are connected in sequence, wherein the sample collecting section track is respectively vertical to the sample loading section track and the sample recovering section track, the track inner width of the sample loading section track and the sample recovering section track is slightly larger than the length of the sample rack, and the track inner width of the sample collecting section track is slightly larger than the width of the sample rack.
2. The apparatus according to claim 1, wherein the first track is a dual track, and four corners of the sample holder are respectively provided with a first card pin, a second card pin, a third card pin and a fourth card pin for cooperating with the four tracks.
3. The apparatus according to claim 1, further comprising a scanning device for scanning the bar code of the sample vial to read the bar code information, wherein the scanning device is disposed at the junction of the sample loading track and the sample collecting track.
4. The automatic immunofluorescence detection apparatus according to claim 1, wherein the sampling device comprises a sampling needle and a mechanical arm for driving the sampling needle to operate within a specified range; the detection device comprises a dilution cup for diluting a sample, a suction and spitting device for uniformly mixing the sample in the dilution cup and an acquisition system for acquiring a fluorescence photo of the diluted sample.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921048125.6U CN210243672U (en) | 2019-07-08 | 2019-07-08 | Full-automatic immunofluorescence detection equipment |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201921048125.6U CN210243672U (en) | 2019-07-08 | 2019-07-08 | Full-automatic immunofluorescence detection equipment |
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| CN210243672U true CN210243672U (en) | 2020-04-03 |
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| CN201921048125.6U Active CN210243672U (en) | 2019-07-08 | 2019-07-08 | Full-automatic immunofluorescence detection equipment |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110221089A (en) * | 2019-07-08 | 2019-09-10 | 深圳市亚辉龙生物科技股份有限公司 | A kind of full-automatic Immunofluorescence test equipment |
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2019
- 2019-07-08 CN CN201921048125.6U patent/CN210243672U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110221089A (en) * | 2019-07-08 | 2019-09-10 | 深圳市亚辉龙生物科技股份有限公司 | A kind of full-automatic Immunofluorescence test equipment |
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