CN210186058U - Preparation facilities of scutellarin aglycone liposome - Google Patents

Preparation facilities of scutellarin aglycone liposome Download PDF

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Publication number
CN210186058U
CN210186058U CN201920363339.6U CN201920363339U CN210186058U CN 210186058 U CN210186058 U CN 210186058U CN 201920363339 U CN201920363339 U CN 201920363339U CN 210186058 U CN210186058 U CN 210186058U
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China
Prior art keywords
reation kettle
water tank
scutellarin aglycone
raw materials
filling tube
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CN201920363339.6U
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Chinese (zh)
Inventor
Limin Tao
陶立敏
Yujing Song
宋宇婧
Xiao Wang
王筱
Xiaxin Sheng
盛夏鑫
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Jiaxing Xin Baylet Biotechnology Co Ltd
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Jiaxing Xin Baylet Biotechnology Co Ltd
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  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The utility model discloses a preparation facilities of scutellarin aglycone liposome, including reation kettle, filling tube, discharging pipe, agitator motor and stirring rake, reation kettle top surface one side is provided with the filling tube, reation kettle bottom fixed surface is provided with the discharging pipe, filling tube one side is provided with agitator motor, the reation kettle inner chamber is provided with the stirring rake, and the stirring rake links to each other with the agitator motor output through the pivot. The utility model discloses a pH value sensor and temperature sensor, can be effectual pH value and the temperature condition of monitoring reation kettle intermediate material to can send monitoring data to monitoring host computer again, then show in the display screen, so that the user improves the pH value of raw materials in a flexible way, through temperature controller, water tank, hot plate, inlet tube and outlet pipe, can effectually carry out nimble heating or cooling to the raw materials in the reation kettle, so that satisfy the activity of raw materials, be fit for being extensively promoted and used.

Description

Preparation facilities of scutellarin aglycone liposome
Technical Field
The utility model relates to a preparation facilities, in particular to preparation facilities of scutellarin aglycone liposome.
Background
Erigeron breviscapus, also known as erigeron breviscapus, herba Gei and flos Helianthi, is a dried whole plant of erigeron breviscapus of Compositae, and is mainly distributed in southwest region of China. Erigeron breviscapus is cold in nature, slightly bitter, sweet, warm and pungent, has effects of diminishing inflammation, relieving pain, dispelling pathogenic wind, removing dampness, promoting blood circulation for removing blood stasis, dredging meridian passage, and can be used for treating cardiovascular disease and cerebrovascular disease. It was first recorded in Yunnan Ben Cao. Erigeron breviscapus as one of the common Chinese herbal medicines widely flows in folks, and can be used for treating rheumatism pain, paralysis and other diseases in the prescriptions of Miao medicine, Tibetan medicine, Zhuang medicine, Baiyao and the like. In 1977, the injection is collected in the department of Chinese pharmacopoeia, and currently, the breviscapine injection which is on the market is mainly used for treating cardiovascular and cerebrovascular system diseases.
Because the stability of scutellarin aglycone is poor, the traditional preparation device of the scutellarin aglycone liposome cannot monitor and adjust the factors such as the pH value, the temperature, various enzymes in vivo and the like of the solution, thereby influencing the stability of the scutellarin aglycone and further reducing the production quality.
SUMMERY OF THE UTILITY MODEL
The utility model discloses a main aim at provides a preparation facilities of scutellarin aglycone liposome, through pH value sensor and temperature sensor, can be effectual pH value and the temperature condition of raw materials in the monitoring reation kettle, and can send monitoring data to the monitoring host computer again, then show in the display screen, so that the user improves the pH value of raw materials in a flexible way, through the temperature controller, the water tank, the hot plate, inlet tube and outlet pipe, can effectually carry out nimble heating or cooling to the raw materials in the reation kettle, so that satisfy the activity of raw materials, can effectively solve the problem in the background art.
In order to achieve the above purpose, the utility model adopts the following technical scheme:
a preparation device of scutellarin aglycone liposome comprises a reaction kettle, a feeding pipe, a discharging pipe, a stirring motor and a stirring paddle, wherein the feeding pipe is arranged on one side of the top surface of the reaction kettle, the discharging pipe is fixedly arranged on the surface of the bottom of the reaction kettle, the stirring motor is arranged on one side of the feeding pipe, the stirring paddle is arranged in an inner cavity of the reaction kettle and is connected with the output end of the stirring motor through a rotating shaft, a pH value sensor is fixedly arranged on one side of the bottom surface of the inner cavity of the reaction kettle, a temperature sensor is arranged on one side of the pH value sensor, a monitoring host is arranged at the bottom of the outer wall surface of the reaction kettle, a display screen is arranged on the top of the outer wall surface of the reaction kettle, a temperature controller is arranged on one side of the bottom of the display screen, water tanks are fixedly, and one side of the bottom of the water tank is fixedly connected with a water outlet pipe.
Furthermore, a switch is arranged on one side of the temperature controller, and electromagnetic valves are fixedly connected to one ends of the discharge pipe, the water inlet pipe and the water outlet pipe in series.
Further, a heat insulation layer is coated on the surface of the outer wall of the water tank.
Further, an anti-sticking coating is coated on the surface of the inner wall of the reaction kettle.
Further, the monitoring host is respectively electrically connected with the stirring motor, the pH value sensor, the temperature sensor, the display screen, the temperature controller, the switch and the electromagnetic valve through wires, and the temperature controller is electrically connected with the heating plate through wires.
Compared with the prior art, the utility model discloses following beneficial effect has:
1. through the filling tube, can effectually add the raw materials to reation kettle in to the discharging pipe can derive the raw materials that the reaction is good again, then through agitator motor, can effectually drive the stirring rake and rotate, thereby can mix the stirring to the raw materials in the reation kettle, through pH value sensor and temperature sensor, the pH value and the temperature condition of raw materials in can effectual monitoring reation kettle, and can send monitoring data to the monitoring host computer again.
Through the monitoring host computer, can be effectual with during monitoring data sends to the display screen, and then can show to the nimble pH value that improves scutellarin aglycone liposome of adding the regulator from the filling tube department of user, when the temperature is not enough, can pass through the temperature controller again, can the operation of effectual control hot plate, thereby can make the hot plate to the water heating in the water tank, and then heat the interior raw materials of reation kettle through the heat transfer.
When the temperature is overheated, through inlet tube and outlet pipe, can effectually derive the cooling and backward flow to the hot water in the water tank to reach the effect to the reation kettle cooling, and then cool down the raw materials, through the switch, opening or closing that can effectual controlgear is nimble.
Through solenoid valve, can effectual derivation or the water tank hydrologic cycle of control raw materials, through the heat preservation, can effectually carry out the heat preservation effect to the water tank, prevent that the water tank cooling is too fast and influence equipment production, through anti-adhesion coating, can effectually prevent that scutellarin aglycone liposome from bonding at the reation kettle inner wall to the clearance in later stage.
Drawings
Fig. 1 is a schematic diagram of the overall structure of the device for preparing scutellarin aglycone liposome of the present invention.
Fig. 2 is a schematic diagram of the internal structure of the device for preparing scutellarin aglycone liposome of the present invention.
Fig. 3 is a schematic side view of the apparatus for preparing scutellarin aglycone liposome of the present invention.
In the figure: 1. a reaction kettle; 2. a feed tube; 3. a discharge pipe; 4. a stirring motor; 5. a stirring paddle; 6. a pH sensor; 7. a temperature sensor; 8. monitoring the host; 9. a display screen; 10. a temperature controller; 11. a water tank; 12. heating plates; 13. a water inlet pipe; 14. a water outlet pipe; 15. a switch; 16. an electromagnetic valve; 17. a heat-insulating layer; 18. and (4) an anti-sticking coating.
Detailed Description
In order to make the technical means, creation features, achievement purposes and functions of the present invention easy to understand, the present invention is further described below with reference to the following embodiments.
As shown in fig. 1-3, a preparation apparatus for scutellarin aglycone liposome comprises a reaction kettle 1, a feeding pipe 2, a discharging pipe 3, a stirring motor 4 and a stirring paddle 5, wherein the feeding pipe 2 is arranged on one side of the top surface of the reaction kettle 1, the discharging pipe 3 is fixedly arranged on the bottom surface of the reaction kettle 1, the stirring motor 4 is arranged on one side of the feeding pipe 2, the stirring paddle 5 is arranged in the inner cavity of the reaction kettle 1, the stirring paddle 5 is connected with the output end of the stirring motor 4 through a rotating shaft, a pH sensor 6 is fixedly arranged on one side of the bottom surface of the inner cavity of the reaction kettle 1, a temperature sensor 7 is arranged on one side of the pH sensor 6, a monitoring host 8 is arranged on the bottom of the outer wall surface of the reaction kettle 1, a display screen 9 is arranged on the top of the outer wall surface of the reaction kettle 1, a temperature controller 10 is arranged on one side, the heating plate 12 is arranged in the inner cavity of the water tank 11, a water inlet pipe 13 is fixedly connected to one side of the top of the water tank 11, and a water outlet pipe 14 is fixedly connected to one side of the bottom of the water tank 11.
As shown in fig. 1-3, in this embodiment, through pH sensor 6 and temperature sensor 7, pH and temperature of raw materials in reation kettle 1 can be monitored effectively, and can send monitoring data to monitoring host 8 again, then show in display screen 9, so that the user improves the pH of raw materials in a flexible way, through temperature controller 10, water tank 11, hot plate 12, inlet tube 13 and outlet pipe 14, can be effectual carry out nimble heating or cooling to the raw materials in reation kettle 1, so as to satisfy the activity of raw materials.
Wherein, a switch 15 is arranged on one side of the temperature controller 10, and one ends of the discharge pipe 3, the water inlet pipe 13 and the water outlet pipe 14 are all fixedly connected with an electromagnetic valve 16 in series.
In this embodiment, as shown in fig. 1, the switch 15 can effectively control the device to be flexibly opened or closed, and the electromagnetic valve 16 can effectively control the discharge of the raw material or the water circulation in the water tank 11.
Wherein, the surface of the outer wall of the water tank 11 is coated with an insulating layer 17.
As shown in FIG. 3, the heat preservation layer 17 can effectively preserve heat of the water tank 11, and the water tank 11 is prevented from being cooled too fast to affect the production of equipment.
Wherein, the anti-sticking coating 18 is smeared on the surface of the inner wall of the reaction kettle 1.
In this embodiment, as shown in fig. 2, the anti-sticking coating 18 can effectively prevent the scutellarin aglycone liposome from sticking to the inner wall of the reaction kettle 1, so as to facilitate the later cleaning.
The monitoring host 8 is electrically connected with the stirring motor 4, the pH value sensor 6, the temperature sensor 7, the display screen 9, the temperature controller 10, the switch 15 and the electromagnetic valve 16 through leads respectively, and the temperature controller 10 is electrically connected with the heating plate 12 through leads.
It should be noted that, the utility model relates to a preparation facilities of scutellarin aglycone liposome, in operation, through filling tube 2, can be effectual add the raw materials to reation kettle 1, and discharging pipe 3 can derive the raw materials that react well again, then through agitator motor 4, can effectively drive stirring rake 5 and rotate, thereby can carry out mixing stirring to the raw materials in reation kettle 1, through pH value sensor 6 and temperature sensor 7, can effectively monitor the pH value and the temperature condition of raw materials in reation kettle 1, and can also send monitoring data to monitoring host computer 8, through monitoring host computer 8, can effectively send monitoring data to display screen 9, and then can show, so that the nimble regulating agent that adds from filling tube 2 of user improves the pH value of scutellarin aglycone liposome, when the temperature is not enough, can pass through temperature controller 10 again, can operate by effectual control hot plate 12, thereby can make hot plate 12 to the water heating in the water tank 11, and then heat the interior raw materials of reation kettle 1 through the heat transfer, when the temperature is overheated, through inlet tube 13 and outlet pipe 14, can effectually derive the cooling and flow back to the hot water in the water tank 11, thereby reach the effect to reation kettle 1 cooling, and then cool down the raw materials, through switch 15, can be nimble open or close of effectual controlgear, through electromagnetic valve 16, derivation or the water tank 11 mesocycle of effectual control raw materials, through heat preservation 17, can effectually keep warm the effect to water tank 11, prevent that water tank 11 from cooling too fast and influence equipment production, through anti-sticking coating 18, can effectually prevent that scutellarin aglycone liposome from bonding at reation kettle 1 inner wall, so that the clearance in later stage.
The utility model relates to a preparation facilities of scutellarin aglycone liposome, including reation kettle 1, filling tube 2, discharging pipe 3, agitator motor 4, stirring rake 5, pH value sensor 6, temperature sensor 7, monitoring host computer 8, display screen 9, temperature controller 10, water tank 11, hot plate 12, inlet tube 13, outlet pipe 14, switch 15, solenoid valve 16, heat preservation 17 and anti-sticking coating 18, the part is general standard component or the part that technical personnel in the field know, its structure and principle all are that this technical personnel all can learn through the technical manual or learn through conventional experimental approach.
The basic principles and the main features of the invention and the advantages of the invention have been shown and described above. It will be understood by those skilled in the art that the present invention is not limited to the above embodiments, and that the foregoing embodiments and descriptions are provided only to illustrate the principles of the present invention without departing from the spirit and scope of the present invention. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (5)

1. The utility model provides a preparation facilities of scutellarin aglycone liposome, includes reation kettle (1), filling tube (2), discharging pipe (3), agitator motor (4) and stirring rake (5), reation kettle (1) top surface one side is provided with filling tube (2), reation kettle (1) bottom fixed surface is provided with discharging pipe (3), filling tube (2) one side is provided with agitator motor (4), reation kettle (1) inner chamber is provided with stirring rake (5), and stirring rake (5) link to each other its characterized in that through pivot and agitator motor (4) output: fixed pH value sensor (6) that is provided with in reation kettle (1) inner chamber bottom surface one side, pH value sensor (6) one side is provided with temperature sensor (7), reation kettle (1) outer wall surface bottom is provided with monitoring host (8), reation kettle (1) outer wall surface top is provided with display screen (9), display screen (9) bottom one side is provided with temperature controller (10), reation kettle (1) outer wall both sides and back surface are all fixed and are provided with water tank (11), water tank (11) inner chamber is provided with hot plate (12), water tank (11) top one side fixedly connected with inlet tube (13), water tank (11) bottom one side fixedly connected with outlet pipe (14).
2. The apparatus for preparing scutellarin aglycone liposome according to claim 1, wherein: a switch (15) is arranged on one side of the temperature controller (10), and one ends of the discharge pipe (3), the water inlet pipe (13) and the water outlet pipe (14) are all fixedly connected with an electromagnetic valve (16) in series.
3. The apparatus for preparing scutellarin aglycone liposome according to claim 1, wherein: and a heat-insulating layer (17) is coated on the outer wall surface of the water tank (11).
4. The apparatus for preparing scutellarin aglycone liposome according to claim 1, wherein: and an anti-sticking coating (18) is coated on the surface of the inner wall of the reaction kettle (1).
5. The apparatus for preparing scutellarin aglycone liposome according to claim 1, wherein: the monitoring host (8) is respectively electrically connected with the stirring motor (4), the pH value sensor (6), the temperature sensor (7), the display screen (9), the temperature controller (10), the switch (15) and the electromagnetic valve (16) through leads, and the temperature controller (10) is electrically connected with the heating plate (12) through leads.
CN201920363339.6U 2019-03-21 2019-03-21 Preparation facilities of scutellarin aglycone liposome Active CN210186058U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201920363339.6U CN210186058U (en) 2019-03-21 2019-03-21 Preparation facilities of scutellarin aglycone liposome

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Application Number Priority Date Filing Date Title
CN201920363339.6U CN210186058U (en) 2019-03-21 2019-03-21 Preparation facilities of scutellarin aglycone liposome

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111514787A (en) * 2020-04-20 2020-08-11 温州飞龙聚氨酯设备工程有限公司 Corrosion-resistant high temperature resistant arc tooth mixing head
CN113117002A (en) * 2021-05-31 2021-07-16 兴安界首骨伤医院有限公司 Dizhi rehmannia pills and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111514787A (en) * 2020-04-20 2020-08-11 温州飞龙聚氨酯设备工程有限公司 Corrosion-resistant high temperature resistant arc tooth mixing head
CN113117002A (en) * 2021-05-31 2021-07-16 兴安界首骨伤医院有限公司 Dizhi rehmannia pills and preparation method thereof

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