CN210175184U - Liquid split charging device - Google Patents

Abstract

The utility model relates to a liquid partial shipment device, include: a machine base; the first driving piece is arranged on the base; the device comprises at least two liquid separation execution modules and at least two liquid separation assemblies, wherein the at least two liquid separation execution modules are connected with the at least two liquid separation assemblies in a one-to-one correspondence manner, and a first driving piece is used for driving all the liquid separation assemblies to move; the liquid carrying component is arranged on the base and comprises at least two liquid containing parts which are isolated from each other, and at least two groups of liquid separating components can correspondingly extend into the at least two liquid containing parts one by one; the tray is used for placing the reagent kit and is arranged on the base, and the liquid in at least two groups of liquid separating assemblies can be injected into at least two rows or two columns of reagent hole sites of the reagent kit in a one-to-one correspondence manner; the control element, the liquid separation execution module and the first driving piece are electrically connected with the control element.

Description

Liquid split charging device

Technical Field

The utility model relates to a partial shipment equipment technical field especially relates to a liquid partial shipment device.

Background

In most of the current medical or biochemical inspection and detection projects, a large number of deep-well plate kits (such as a common 96-deep-well plate) are needed, in some projects, different rows or different columns of reagent hole sites of the kit need to store different reagents, in most reagent manufacturers, the reagent dispensing operation is basically performed manually, and the defects of manual operation are obvious, such as low efficiency and easy error, wherein the reagent dispensing of any row or column has errors, and the whole kit can only be used for waste treatment.

SUMMERY OF THE UTILITY MODEL

Therefore, there is a need for a liquid dispensing apparatus, which can automatically dispense reagents and meet the requirements of storing different reagents in different rows or different columns of reagent wells of a reagent kit.

The technical scheme is as follows:

a liquid dispensing apparatus comprising: a machine base; the first driving piece is arranged on the base; the device comprises at least two liquid separation execution modules and at least two liquid separation assemblies, wherein the at least two liquid separation execution modules are connected with the at least two liquid separation assemblies in a one-to-one correspondence manner, and the first driving piece is used for driving all the liquid separation assemblies to move; the liquid carrying component is arranged on the base and comprises at least two liquid containing parts which are isolated from each other, and at least two groups of liquid separating components can correspondingly extend into the at least two liquid containing parts one by one; the tray is used for placing the reagent kit and is arranged on the base, and the liquid in at least two groups of the liquid separating assemblies can be injected into at least two rows or two columns of reagent hole sites of the reagent kit in a one-to-one correspondence manner; and the liquid separation execution module and the first driving piece are electrically connected with the control element.

Foretell liquid partial shipment device is in the course of the work, at least two sets of minute liquid subassemblies at first stretch into the liquid holding part of two at least mutual isolations of carrier liquid spare under the drive of first driving piece one-to-one, then under the effect of dividing liquid execution module, divide liquid subassembly to inhale liquid from liquid holding part, then at least two sets of minute liquid subassemblies again move to the top of the reagent hole site of two at least lines or two at least of kit under the drive of first driving piece one-to-one, at last under the effect of dividing liquid execution module, divide liquid subassembly to inject liquid into the reagent hole site in, accomplish the partial shipment of liquid. In order to above liquid partial shipment device, different kinds of reagent can be placed respectively to two at least liquid container parts on the carrier liquid spare, control element can control branch liquid as required and carry out the module and absorb an amount of reagent through dividing the liquid subassembly, then pour into corresponding reagent hole site with reagent through dividing the liquid subassembly again, accomplish quantitative partial shipment, so, control action through control element, foretell liquid partial shipment device can realize the partial shipment of reagent automatically, and can satisfy the different rows of kit or the requirement that different reagent hole sites of different columns deposited different reagents.

The technical solution is further explained below:

in one embodiment, the machine base comprises a machine table and a machine head arranged opposite to the machine table at intervals, the liquid separating assemblies are arranged on the machine head, the tray is movably arranged on the machine table and can move to a position opposite to the liquid separating assemblies, and the first driving piece is used for driving all the liquid separating assemblies to be close to or far away from the tray.

In one embodiment, the liquid carrier component is movably disposed on the machine platform and can be moved to a position opposite to the liquid separation components, and the first driving component is used for driving all the liquid separation components to approach or depart from the liquid carrier component.

In one embodiment, the liquid dispensing apparatus further includes at least two liquid replenishing mechanisms, the at least two liquid replenishing mechanisms correspond to the at least two liquid accommodating portions one to one, the liquid replenishing mechanism includes a liquid replenishing source disposed on the base, a liquid replenishing pipe communicated with the liquid replenishing source, and a liquid level detecting element disposed on the base, the liquid replenishing pipe is used for introducing liquid into the liquid accommodating portions, the liquid level detecting element is used for detecting the height of the liquid in the liquid accommodating portions, and the liquid replenishing source and the liquid level detecting element are both electrically connected to the control element.

In one embodiment, the liquid dispensing apparatus further includes a second driving member electrically connected to the control element, the second driving member is disposed on the base and is in driving connection with the liquid carrying member, and the second driving member is configured to drive the liquid carrying member to move to and from a liquid replenishing level and a liquid extracting level.

In one embodiment, the liquid dispensing device further includes a third driving member electrically connected to the control element, the third driving member is disposed on the base and electrically connected to the liquid level detection element, and the third driving member is used to drive the liquid level detection element to move to and from the detection position and the avoidance position.

In one embodiment, the liquid dispensing apparatus further includes a fourth driving member electrically connected to the control element, the fourth driving member is disposed on the base and is drivingly connected to the tray, and the fourth driving member is configured to drive the tray to move to and from a dispensing position and a cassette-taking position.

In one embodiment, the liquid dispensing device further comprises an identification element electrically connected with the control element, and the identification element is arranged on the base and used for identifying the type of the tray.

In one embodiment, the liquid dispensing device further comprises a mounting frame, all the liquid distribution assemblies are detachably arranged on the mounting frame, and the first driving member is in driving connection with the mounting frame.

In one embodiment, at least two groups of the liquid separation assemblies are arranged in rows, each liquid separation assembly comprises at least two liquid separation heads, and at least two liquid separation heads in the same liquid separation assembly are arranged in columns.

The technical scheme also provides a liquid subpackaging method, which comprises the following steps:

the at least two groups of liquid separating assemblies are driven by the first driving member to correspondingly extend into at least two mutually isolated liquid accommodating parts of the liquid carrying member one by one;

under the action of the liquid separation execution module, the liquid separation assembly sucks liquid from the liquid containing part;

the at least two groups of liquid separating assemblies are driven by the first driving piece to move to the positions above the at least two rows or columns of reagent hole positions of the reagent kit in a one-to-one correspondence manner;

under the effect of dividing liquid and executing the module, divide liquid subassembly to pour into liquid into the reagent hole site, accomplish the partial shipment of liquid.

In order to above in the liquid partial shipment method, different kinds of reagent can be placed respectively to two at least liquid container parts on the carrier liquid spare, control element can control branch liquid as required and carry out the module and absorb an amount of reagent through dividing the liquid subassembly, then pour into corresponding reagent hole site with reagent through dividing the liquid subassembly again, accomplish quantitative partial shipment, so, control action through control element, the partial shipment of reagent can be realized automatically to foretell liquid partial shipment device, and can satisfy the different rows of kit or the reagent hole site of different rows, deposit the requirement of different reagents.

Drawings

Fig. 1 is a schematic view of an explosion structure at a first viewing angle of a liquid dispensing apparatus according to an embodiment of the present invention;

fig. 2 is a schematic view of an exploded structure at a second viewing angle of a liquid dispensing apparatus according to an embodiment of the present invention;

fig. 3 is a schematic structural view of a liquid dispensing apparatus according to an embodiment of the present invention;

FIG. 4 is an enlarged view of a portion A of the liquid dispensing apparatus shown in FIG. 3;

fig. 5 is a partial sectional view of a liquid dispensing apparatus according to an embodiment of the present invention.

Description of reference numerals:

10. the kit comprises a kit body, 11, reagent hole sites, 20, a liquid supplementing level, 30, a liquid taking level, 40, a detection level, 50, an avoidance level, 60, a split charging level, 70, a box taking level, 100, a machine base, 110, a machine table, 120, a machine head, 200, a first driving piece, 300, a liquid division execution module, 400, a liquid division component, 410, a liquid division head, 500, a liquid carrying piece, 510, a liquid containing part, 600, a tray, 710, a liquid supplementing source, 720, a liquid supplementing pipe, 730, a liquid level detection element, 740, a third driving piece, 800 and a mounting frame.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more clearly understood, the present invention will be further described in detail with reference to the accompanying drawings and the following detailed description. It should be understood that the detailed description and specific examples, while indicating the scope of the invention, are intended for purposes of illustration only and are not intended to limit the scope of the invention.

It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "left," "right," and the like as used herein are for illustrative purposes only and do not represent the only embodiments.

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.

In the present invention, the terms "first" and "second" do not denote any particular quantity or order, but are merely used to distinguish names.

As shown in fig. 1, 3, 4 and 5, a liquid dispensing apparatus according to an embodiment includes: the liquid container comprises a machine base 100, a first driving member 200, at least two liquid separating execution modules 300, at least two liquid separating assemblies 400, a liquid carrying member 500, a tray 600 and a control element.

The first driving member 200 is disposed on the base 100; the at least two liquid separation execution modules 300 are connected with the at least two liquid separation assemblies 400 in a one-to-one correspondence manner, and the first driving member 200 is used for driving all the liquid separation assemblies 400 to move; the carrier liquid 500 is disposed on the base 100, the carrier liquid 500 includes at least two liquid accommodating portions 510 that are isolated from each other, and at least two sets of liquid separating assemblies 400 can correspondingly extend into the at least two liquid accommodating portions 510 one by one; the tray 600 is used for placing the reagent kit 10, the tray 600 is arranged on the machine base 100, and the liquid in at least two groups of liquid separation assemblies 400 can be injected into at least two rows or two columns of reagent hole sites 11 of the reagent kit 10 in a one-to-one correspondence manner; the liquid separation executing module 300 and the first driving member 200 are electrically connected to the control element.

Specifically, the processing chip of the control element may be, but not limited to, a single chip, an ARM (advanced risc Machine), and an FPGA (Field-Programmable Gate Array), the liquid separation execution module 300 includes a syringe, and a driving source connected to a piston rod of the syringe, the driving source is electrically connected to the control element, the driving source is used for driving the piston rod to perform telescopic motion in a barrel of the syringe, the liquid separation assembly 400 includes a liquid separation head 410, and the syringe is communicated with the liquid separation head 410 through a hose. The driving source may be any mechanism that drives the piston rod to move telescopically, such as an air cylinder, a transmission belt mechanism, an electric screw rod, and the like, and the liquid separation head 410 is a gun head or a suction nozzle. Wherein, the driving source is controlled by a precise digital driver, and micro-packaging can be realized.

It should be noted that the structural form of the liquid separation performing module 300 is not limited to the above-mentioned form, and any mechanism capable of sucking the liquid through the liquid separation assembly 400 or discharging the liquid from the liquid separation assembly 400 is within the protection scope of the present application.

In the working process of the liquid subpackaging device, at least two groups of liquid separating assemblies 400 firstly extend into at least two mutually isolated liquid accommodating parts 510 of the liquid carrying component 500 in a one-to-one correspondence manner under the driving of the first driving component 200, then the liquid separating assemblies 400 suck liquid from the liquid accommodating parts 510 under the action of the liquid separating execution module 300, then the at least two groups of liquid separating assemblies 400 are further driven by the first driving component 200 to move to the positions above at least two rows or at least two columns of reagent hole sites 11 of the reagent kit 10 in a one-to-one correspondence manner, and finally the liquid separating assemblies 400 inject the liquid into the reagent hole sites 11 under the action of the liquid separating execution module 300 to complete the subpackaging of the liquid. Among the above liquid partial shipment device, different kinds of reagent can be placed respectively to two at least liquid container parts 510 on the carrier liquid spare 500, control element can control branch liquid as required and carry out module 300 and absorb a quantitative reagent through dividing liquid subassembly 400, then inject corresponding reagent hole site 11 with reagent through dividing liquid subassembly 400, accomplish quantitative partial shipment, thus, control action through control element, the partial shipment of reagent can be realized automatically to foretell liquid partial shipment device, and can satisfy the different lines of kit 10 or the reagent hole site 11 of different rows, deposit the requirement of different reagents.

Specifically, in this embodiment, there are 12 liquid separation execution modules 300, each liquid separation execution module 300 has 8 or 12 syringes, and all syringes of the same liquid separation execution module 300 are driven by the same driving source, the number of the liquid separation assemblies 400 is also 12, each liquid separation assembly 400 has 8 or 12 liquid separation heads 410, 12 liquid separation execution modules 300 and 12 liquid separation assemblies 400 are in one-to-one correspondence, and 8 or 12 syringes in a single liquid separation execution module 300 are connected with 8 or 12 liquid separation heads 410 in a single liquid separation assembly 400 in one-to-one correspondence, the liquid accommodating portions 510 of the liquid carrying member 500 are 12, and 12 liquid separation assemblies 400 can correspondingly extend into 12 liquid accommodating portions 510, wherein the liquid accommodating portions 510 can be elongated grooves or elongated blind holes formed in the liquid carrying member 500.

As shown in fig. 3 and 5, in one embodiment, the base 100 includes a machine table 110 and a machine head 120 spaced apart from and opposite to the machine table 110, the dispensing assemblies 400 are disposed on the machine head 120, the tray 600 is movably disposed on the machine table 110 and can be moved to a position opposite to the dispensing assemblies 400, and the first driving member 200 is used for driving all the dispensing assemblies 400 to approach or move away from the tray 600. Therefore, the first driving member 200 only needs to drive the liquid distribution assembly 400 to make linear motion, so that the liquid distribution assembly 400 is close to the reagent hole 11, the structure is simple, the moving path of the liquid distribution assembly 400 is short, and the required time is short. In addition, the tray 600 can move on the machine base 110, and the position of the tray 600 and the position of the liquid carrier 500 can be staggered, so that the liquid separation assembly 400 can move into the liquid containing part 510 and suck the liquid under the driving of the first driving member 200, and then the tray 600 moves to the position opposite to the liquid separation assembly 400, so that the liquid separation assembly 400 can be opposite to the reagent hole site 11 of the reagent kit 10 on the tray 600.

Specifically to this embodiment, the machine table 110 is disposed at the bottom, the machine head 120 is disposed on the upper portion of the machine table 110 through the supporting plate, the machine head 120 is of a hollow structure, the control element, the liquid separation execution module 300 and the like are disposed in the machine head 120, the liquid separation assembly 400 is disposed at the bottom of the machine table 110, the tray 600 is disposed on the machine table 110 and located above the liquid carrier 500, and the first driving member 200 can be any mechanism capable of driving the liquid separation assembly 400 to perform linear motion in the vertical direction, such as an air cylinder, a transmission belt mechanism, an electric screw rod and the like.

In one embodiment, the liquid dispensing apparatus further includes a fourth driving member electrically connected to the control element, the fourth driving member is disposed on the base 100 and is drivingly connected to the tray 600, and the fourth driving member is configured to drive the tray 600 to move to and from the dispensing position 60 and the cassette taking position 70. In this way, the tray 600 can move under the driving of the fourth driving part, and the automation degree of the whole device can be improved because the fourth driving part is controlled by the control element; of course, the tray 600 may be moved manually without being moved by the fourth driver.

Wherein, the dispensing position 60 is a position opposite to the dispensing assembly 400, and when the kit 10 is placed on the tray 600 and the tray 600 moves to the dispensing position 60, the dispensing head 410 of the dispensing assembly 400 is just opposite to the reagent hole 11 of the tray 600; the above-mentioned cassette taking station 70 is a position located at the front side of the dispensing station 60, and when the tray 600 moves to the cassette taking station 70, the worker can take out the reagent cassettes 10 already dispensed with the liquid on the tray 600, and can put the empty reagent cassettes 10 from the cassette taking station 70 onto the tray 600. It should be noted that the fourth driving member may be any mechanism capable of driving the tray 600 to move back and forth, such as an air cylinder, a belt mechanism, an electric screw, and the like.

As shown in fig. 5, further, the liquid carrier 500 is movably disposed on the machine table 110 and can be moved to a position opposite to the liquid separating assembly 400, and the first driving member 200 is used for driving the liquid separating assembly 400 to approach or move away from the liquid carrier 500. Thus, the first driving member 200 only needs to drive the liquid distribution assembly 400 to make a linear motion, so that the liquid distribution assembly 400 can extend into the liquid accommodating portion 510 of the liquid carrier 500, the structure is simple, the moving path of the liquid distribution assembly 400 is short, and the required time is short.

As shown in fig. 2 and 5, in one embodiment, the liquid dispensing apparatus further includes at least two liquid replenishing mechanisms, the at least two liquid replenishing mechanisms correspond to the at least two liquid containing portions 510 one to one, the liquid replenishing mechanisms include a liquid replenishing source 710 disposed on the base 100, a liquid replenishing pipe 720 communicated with the liquid replenishing source 710, and a liquid level detecting element 730 disposed on the base 100, the liquid replenishing pipe 720 is used for introducing liquid into the liquid containing portions 510, the liquid level detecting element 730 is used for detecting the height of the liquid in the liquid containing portions 510, and the liquid replenishing source 710 and the liquid level detecting element 730 are both electrically connected to the control element. The liquid level detecting element 730 can detect the liquid level in the liquid containing part 510 and then transmit a signal to the control element, when the liquid level is lower than a preset value, the control element controls the liquid replenishing source 710 to work, and the liquid replenishing pipe 720 replenishes liquid into the liquid containing part 510, so that the device can work efficiently and continuously.

Specifically, in the present embodiment, the number of the fluid infusion mechanisms is 12, 12 fluid infusion mechanisms correspond to 12 liquid containers 510 one to one, each fluid infusion mechanism includes a fluid infusion source 710, a fluid infusion tube 720 communicated with the fluid infusion source 710, and a liquid level detection element 730, 12 fluid infusion tubes 720 correspond to 12 liquid containers 510 one to one, and 12 liquid level detection elements 730 correspond to 12 liquid containers 510 one to one. Wherein, the fluid replacement source 710 may be a diaphragm pump; the liquid level detection elements 730 may be a laser sensor, a liquid level sensor, etc., 12 liquid level detection elements 730 may form an integrated structure, or may be disposed dispersedly, and the 12 liquid level detection elements 730 are disposed to be opposite to the 12 liquid accommodating portions 510 of the carrier liquid 500 in a one-to-one correspondence manner.

Further, the liquid dispensing apparatus further includes a second driving member electrically connected to the control element, the second driving member is disposed on the base 100 and is in driving connection with the liquid carrying member 500, and the second driving member is used for driving the liquid carrying member 500 to move to and from the liquid replenishing level 20 and the liquid extracting level 30. In this way, the carrier liquid 500 can move under the driving of the second driving element, and the automation degree of the whole device can be improved as the second driving element is controlled by the control element; of course, the carrier liquid 500 may be moved not by the second driving member but by a manual operation.

Wherein, fluid infusion pipe 720 passes through the support setting in frame 100, and fluid infusion level 20 is the position relative with fluid infusion pipe 720's liquid outlet, gets liquid level 30 for dividing the position that liquid level assembly 400 is relative, and when liquid level 500 removed fluid infusion level 20, fluid infusion mechanism can carry out the fluid infusion to liquid level 500, and when liquid level 500 removed and gets liquid level 30, divide liquid assembly 400 can stretch into in liquid containing portion 510, get liquid.

In the present embodiment, the liquid taking level 30 and the liquid supplementing level 20 are located on the same straight line, and the liquid taking level 30 is located in front of the liquid supplementing level 20, so that the second driving member only needs to drive the liquid carrying member 500 to make a linear motion in the front-rear direction. It should be noted that the second driving member may be any mechanism capable of driving the tray 600 to move back and forth, such as an air cylinder, a belt mechanism, an electric screw, etc.

As shown in fig. 5, the liquid dispensing apparatus further includes a third driving member 740 electrically connected to the control element, the third driving member 740 is disposed on the base 100 and electrically connected to the liquid level detecting element 730, and the third driving member 740 is used for driving the liquid level detecting element 730 to move to and from the detecting position 40 and the avoiding position 50. Thus, when the internal components of the base 100 need to be replaced or maintained, the liquid level detecting element 730 can be driven by the third driving member 740 to move to the avoiding position 50, so as to facilitate the replacement or maintenance of the internal components.

When the liquid level detecting element 730 is located at the detecting position 40, the liquid level detecting element 730 can detect the liquid level in the liquid containing part 510, and when the liquid level detecting element 730 is located at the avoiding position 50, the liquid level detecting element 730 does not prevent a worker from replacing or repairing the internal parts of the machine base 100.

Specifically, in the present embodiment, the liquid level detecting element 730 is disposed above the liquid carrying member 500, and when the liquid carrying member 500 needs to be replaced, the liquid level detecting element 730 must be lifted to a certain height to facilitate the replacement of the liquid carrying member 500, and it should be noted that the third driving member 740 may be any mechanism capable of driving the liquid level detecting element 730 to move up and down, such as an air cylinder, a transmission belt mechanism, an electric screw, and the like.

Further, the liquid outlet end of the liquid supplementing pipe 720 is also in driving connection with the third driving member 740, and the third driving member 740 is used for driving the liquid outlet end of the liquid supplementing pipe 720 to move up and down.

It should be noted that the fluid infusion mechanism and the liquid separation execution module 300 described above work in an independent manner, and each takes its own role, so as to ensure efficient operation of the device and meet the requirements of the use in the reagent production workshop.

As shown in fig. 3 and 4, in one embodiment, the liquid dispensing apparatus further includes an identification component electrically connected to the control component, and the identification component is disposed on the base 100 and used for identifying the type of the tray 600. Different trays 600 are used for installing different reagent kits 10, and by identifying the type of the tray 600, the type of the reagent kit 10 can be determined, and the liquid dosage required to be dispensed in different reagent hole sites 11 in the reagent kit 10 can be understood.

Specifically, identification element can be the camera, identification probes such as camera, be provided with the two-dimensional code on the tray 600, identification member such as bar code, identification element is through effectively discerning the identification member on the tray 600, and then can learn the type of tray 600, thereby learn the specification model parameter signal that corresponds kit 10 on the tray 600, later identification element transmits this parameter signal for control element, and divide the liquid measurement of liquid execution module 300 single partial shipment in time through control element, thereby avoid appearing the liquid partial shipment not enough or too much problem, ensure that the device has reliable partial shipment precision.

As shown in fig. 4 and 5, in one embodiment, the liquid dispensing apparatus further includes a mounting frame 800, all the liquid distribution assemblies 400 are detachably disposed on the mounting frame 800, and the first driving member 200 is drivingly connected to the mounting frame 800. In this manner, replacement of the dispensing assembly 400 may be accomplished. Specifically, the dispensing assembly 400 includes a dispensing head 410, wherein the dispensing head 410 employs a Tip head consumable that is easily replaceable.

Further, at least two groups of liquid separating assemblies 400 are arranged in rows, each liquid separating assembly 400 comprises at least two liquid separating heads 410, and at least two liquid separating heads 410 in the same liquid separating assembly 400 are arranged in columns. Thus, all the liquid-separating heads 410 are matched to form an array structure, which can correspond to the reagent holes 11 arranged in an array on the reagent kit 10 one by one.

The liquid split charging device in the embodiment specifically comprises the following working processes:

1. after all the work is ready, the liquid separating assembly 400 is driven by the first driving member 200 to move downwards to a certain height, so that the liquid separating assembly 400 extends into the liquid containing part 510 of the carrier liquid 500;

2. the liquid separation execution module 300 is started to absorb a certain amount of reagent;

3. the first driving member 200 drives the liquid separating assembly 400 to move upwards to a specific height;

4. the tray 600 carrying the target reagent cartridge 10 (empty reagent cartridge) moves inward to reach the dispensing position 60;

5. the liquid separating component 400 moves downwards to a certain specific height under the action of the first driving component 200, so that the liquid separating component 400 extends into the target kit 10;

6. the liquid separation execution module 300 is started to discharge a certain amount of reagents into the target kit 10;

7. the liquid separating assembly 400 returns to a certain height upwards under the action of the first driving member 200;

8. the tray 600 carrying the target reagent cartridge 10 (already dispensed with the reagent) is moved outward to the cartridge retrieval position 70;

9. after the tray 600 is stopped, the operator walks around the reagent vessel 10 and puts an empty reagent vessel 10, and the apparatus automatically repeats the steps 1-8 above.

In the process of dispensing, the replenishment liquid source 710, the second driving member, and the liquid level detection element 730 are also operated in synchronization without interfering with each other, and when the liquid level in the reagent storage portion is lower than a predetermined height, the replenishment liquid source 710 is activated to replenish the reagent storage portion with the reagent.

The liquid dispensing device described above can be applied to reagent dispensing in 96-well deep-well plates, which are commonly used in the industry, but not limited thereto.

An embodiment further relates to a liquid dispensing method, which is applied to the liquid dispensing device, and comprises the following steps:

s100, the at least two liquid separating assemblies 400 are driven by the first driving member 200 to correspondingly extend into the at least two mutually isolated liquid accommodating portions 510 of the liquid carrying member 500 one by one;

s200, under the action of the liquid separation execution module 300, the liquid separation assembly 400 sucks liquid from the liquid containing part 510;

s300, the at least two groups of liquid separating assemblies 400 are driven by the first driving member 200 to correspondingly move to the positions above the reagent holes 11 in at least two rows or columns of the reagent kit 10;

s400, under the action of the liquid separation execution module 300, the liquid separation assembly 400 injects the liquid into the reagent hole 11, and the liquid is subpackaged.

In the above liquid subpackaging method, at least two liquid accommodating parts 510 on the liquid carrying component 500 can respectively contain different types of reagents, the control element can control the liquid separating execution module 300 to absorb a certain amount of reagents through the liquid separating assembly 400 according to needs, then the reagents are injected into the corresponding reagent hole sites 11 through the liquid separating assembly 400, quantitative subpackaging is completed, and thus, the control action through the control element can automatically realize the subpackaging of the reagents by the liquid subpackaging device, the reagent hole sites 11 of different rows or different columns of the reagent kit 10 can be met, and the requirements of different reagents are stored.

The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.

The above-mentioned embodiments only represent some embodiments of the present invention, and the description thereof is specific and detailed, but not to be construed as limiting the scope of the present invention. It should be noted that, for those skilled in the art, without departing from the spirit of the present invention, several variations and modifications can be made, which are within the scope of the present invention. Therefore, the protection scope of the present invention should be subject to the appended claims.

Claims (10)

1. A liquid dispensing apparatus, comprising:

a machine base;

the first driving piece is arranged on the base;

the liquid separating device comprises at least two liquid separating execution modules and at least two liquid separating components, wherein the at least two liquid separating execution modules are correspondingly connected with the at least two liquid separating components one to one, and the first driving piece is used for driving all the liquid separating components to move;

the liquid carrying component is arranged on the base and comprises at least two liquid containing parts which are isolated from each other, and at least two groups of liquid separating components can correspondingly extend into the at least two liquid containing parts one by one;

the tray is used for placing the reagent kit and is arranged on the base, and the liquid in at least two groups of liquid separating assemblies can be injected into at least two rows or at least two columns of reagent hole sites of the reagent kit in a one-to-one correspondence manner;

and the liquid separation execution module and the first driving piece are electrically connected with the control element.

2. The liquid split charging device according to claim 1, wherein the base comprises a machine table and a machine head arranged opposite to the machine table at an interval, the liquid separating assembly is arranged on the machine head, the tray is movably arranged on the machine table and can move to a position opposite to the liquid separating assembly, and the first driving member is used for driving all the liquid separating assemblies to be close to or far away from the tray.

3. The liquid dispensing apparatus as claimed in claim 2, wherein the liquid carrier is movably disposed on the platform and is movable to a position opposite to the liquid separating assemblies, and the first driving member is configured to drive all of the liquid separating assemblies to move closer to or away from the liquid carrier.

4. The liquid dispensing apparatus according to claim 1, further comprising at least two liquid supply mechanisms, wherein the at least two liquid supply mechanisms correspond to the at least two liquid containers one to one, the liquid supply mechanisms comprise a liquid supply source disposed on the base, a liquid supply pipe communicated with the liquid supply source, and a liquid level detection element disposed on the base, the liquid supply pipe is used for introducing liquid into the liquid containers, the liquid level detection element is used for detecting the height of the liquid in the liquid containers, and the liquid supply source and the liquid level detection element are both electrically connected to the control element.

5. The liquid dispensing apparatus as claimed in claim 4, further comprising a second driving member electrically connected to the control element, wherein the second driving member is disposed on the base and drivingly connected to the liquid carrying member, and the second driving member is configured to drive the liquid carrying member to and from a liquid replenishing level and a liquid extracting level.

6. The liquid split charging device according to claim 4 or 5, further comprising a third driving member electrically connected to the control element, wherein the third driving member is disposed on the base and electrically connected to the liquid level detection element, and the third driving member is configured to drive the liquid level detection element to move to and from the detection position and the avoidance position.

7. The liquid dispensing apparatus according to claim 1, further comprising a fourth driving member electrically connected to the control element, wherein the fourth driving member is disposed on the base and drivingly connected to the tray, and the fourth driving member is configured to drive the tray to move to and from the dispensing position and the cassette-taking position.

8. The liquid dispensing apparatus as claimed in claim 1, further comprising an identification element electrically connected to the control element, the identification element being disposed on the housing for identifying the type of the tray.

9. The liquid dispensing apparatus as claimed in claim 1, further comprising a mounting frame, all of the dispensing assemblies being detachably disposed on the mounting frame, the first driving member being drivingly connected to the mounting frame.

10. The liquid dispensing apparatus of claim 1, wherein at least two sets of said dispensing assemblies are arranged in rows, said dispensing assemblies comprise at least two dispensing heads, and at least two dispensing heads of a same dispensing assembly are arranged in columns.

Images