CN210072187U - Portable fluorescence microscope of can zooming based on smart mobile phone - Google Patents
Portable fluorescence microscope of can zooming based on smart mobile phone Download PDFInfo
- Publication number
- CN210072187U CN210072187U CN201920684688.8U CN201920684688U CN210072187U CN 210072187 U CN210072187 U CN 210072187U CN 201920684688 U CN201920684688 U CN 201920684688U CN 210072187 U CN210072187 U CN 210072187U
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- base plate
- supporting plate
- fluorescence microscope
- mounting hole
- smart phone
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- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
A variable-focus portable fluorescence microscope based on a smart phone comprises the smart phone, a fluorescence microscope group and a support; the support comprises an upper base plate and a lower base plate, a first supporting plate, a second supporting plate and a third supporting plate which are parallel to each other are further arranged between the upper base plate and the lower base plate, the fluorescence microscope module comprises a long-pass filter, an external microscope, a liquid lens and a fluorescence light source, and the long-pass filter, the external microscope and the liquid lens are respectively arranged on the first supporting plate, the second supporting plate and the third supporting plate. The utility model has the advantages that: the adoption of the zoom liquid lens can effectively enlarge the depth of field; the fluorescent microscope group is integrated on a small bracket, so that fluorescent imaging and analysis can be carried out on a microscopic sample in a portable manner; the method makes full use of the image processing capability of the smart phone, reduces the requirements of the fluorescence microscopy technology on experimental environment and conditions, and makes real-time fluorescence microscopy imaging and analysis under special environment more convenient.
Description
Technical Field
The utility model relates to a microscope field, concretely relates to portable fluorescence microscope can zoom based on smart mobile phone.
Background
Fluorescence microscopes are widely used in chemical laboratories and research laboratories, and are often used to study absorption, transportation, distribution and location of chemicals, and also substances in cells, and they use light with specific wavelength to irradiate the object to be examined to generate fluorescence for microscopic examination. The current commercialized fluorescent microscope system is complex, comprises a high-pressure mercury lamp light source, imaging equipment, an excitation filter, a dichroic beam splitter, a blocking filter, a focusing auxiliary device and the like, the overall size of the equipment is generally tens of centimeters, the price is about tens of thousands of yuan RMB, and the portability is poor. In recent years, with the continuous development of built-in imaging systems of smart phones and image processing functions based on mobile phone App software, portability and individualization of fluorescent microscopes become possible.
SUMMERY OF THE UTILITY MODEL
In view of this, an embodiment of the present invention provides a variable-focus portable fluorescence microscope based on a smart phone, including a smart phone, a fluorescence microscope set and a bracket; the support comprises an upper base plate, a lower base plate and an accommodating cavity arranged between the upper base plate and the lower base plate, the upper base plate is used for placing the smart phone, a lens hole matched with a lens of the smart phone is formed in the upper base plate, and the lower base plate is used for placing a sample to be tested; a first supporting plate, a second supporting plate and a third supporting plate which are parallel to each other are sequentially arranged in the accommodating cavity from top to bottom, a first mounting hole is formed in the first supporting plate, a second mounting hole is formed in the second supporting plate, a third mounting hole is formed in the third supporting plate, the centers of the first mounting hole, the second mounting hole, the third mounting hole and the lens hole are on the same straight line, and the fluorescence microscope module comprises a long-pass filter, an external double mirror, a liquid lens and a fluorescence light source; the fluorescent light source is arranged above the bottom plate, the long-pass filter is embedded on the first supporting plate, the external lens is embedded on the second supporting plate, and the liquid lens is embedded on the third supporting plate.
Further, be equipped with a constant head tank on the lower plate, the constant head tank sets up under the third mounting hole, the constant head tank is used for placing the sample.
Furthermore, three of the four side walls of the accommodating cavity are fixedly arranged supporting plates, and the other side wall is a detachable end cover.
Further, the inner surface of the containing cavity is coated with a black aluminum foil which is not transparent to light.
Furthermore, the edge of the upper base plate is provided with a raised positioning table, the positioning table is used for positioning the smart phone, and the smart phone is limited in the middle of the positioning table.
Further, the fluorescent light source is an annular UVLED light source, and the annular UVLED light source is fixed on the lower surface of the third supporting plate.
Further, the focal length of the liquid lens is adjustable.
Furthermore, a rectangular hole is formed in a supporting plate on the side face of the accommodating cavity.
The utility model has the advantages that: the adoption of the zoom liquid lens can effectively enlarge the depth of field; the fluorescent microscope group is integrated on a small bracket, so that fluorescent imaging and analysis can be carried out on a microscopic sample in a portable manner; the method makes full use of the image processing capability of the smart phone, reduces the requirements of the fluorescence microscopy technology on experimental environment and conditions, and makes real-time fluorescence microscopy imaging and analysis under special environment more convenient.
Drawings
Fig. 1 is the utility model relates to a portable fluorescence microscope support 1 that can zoom and smart mobile phone 2's schematic structure view based on smart mobile phone.
Fig. 2 is a schematic structural view of the stent 1 in fig. 1.
Fig. 3 is a schematic sectional structure view of the stent 1 in fig. 1.
Fig. 4 is a working schematic diagram of the variable-focus portable fluorescence microscope based on the smart phone of the present invention.
In the figure: 1-bracket, 2-smart phone, 3-fluorescence microscope module, 10-upper base plate, 11-lower base plate, 12-support plate, 121-rectangular hole, 13-end cover, 14-positioning table, 15-lens hole, 16-positioning groove, 17-first supporting plate, 171-first mounting hole, 18-second supporting plate, 181-second mounting hole, 19-third supporting plate, 191-third mounting hole, 31-long pass filter, 32-external power lens, 33-liquid lens and 34-fluorescence light source.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention clearer, embodiments of the present invention will be further described below with reference to the accompanying drawings.
As shown in fig. 1, a variable focus portable fluorescence microscope based on a smart phone includes a smart phone 2, a support 1, and a fluorescence microscope module 3 (not shown in fig. 1).
The support comprises an upper base plate 10 and a lower base plate 11, the upper base plate 10 and the lower base plate 11 are arranged vertically and in parallel relatively, supporting plates 12 are fixedly arranged on three sides between the upper base plate 10 and the lower base plate 11 and used for supporting the upper base plate and the lower base plate, a detachable end cover 13 is arranged on the other side, the end cover 13 and the upper base plate 10, the lower base plate 11 and the three supporting plates 12 jointly form a shell with an accommodating cavity, the shell is made of light-tight materials, and the inner surface of the accommodating cavity is coated with light-tight black aluminum foils and used for reducing autofluorescence interference imaging of other materials outside the sample under the excitation of a fluorescence light source.
As shown in fig. 2, the upper plate 10 is used for placing the smart phone 2, a plurality of raised positioning tables 14 are arranged at the edge of the upper plate 10 for positioning the smart phone 2, the smart phone 2 is limited in the middle of the plurality of positioning tables 14, a lens hole 15 matched with a lens of the smart phone 2 is further arranged on the upper plate 10, the lens hole 15 is a through hole and is opposite to the lens of the smart phone 15, a positioning groove 16 is arranged on the lower plate 11, and the positioning groove 16 is used for placing a sample.
As shown in fig. 3, a first supporting plate 17, a second supporting plate 18 and a third supporting plate 19 which are parallel to each other are sequentially disposed from top to bottom between the upper base plate 10 and the lower base plate 11, the first supporting plate 17 is provided with a through first mounting hole 171, the second supporting plate 18 is provided with a through second mounting hole 181, the third supporting plate 19 is provided with a through third mounting hole 191, the first mounting hole 171, the second mounting hole 181, the third mounting hole 191 and the lens hole 15 are directly opposite to the positioning groove 16, further, centers of the first mounting hole 171, the second mounting hole 181, the third mounting hole 191 and the lens hole 15 are on the same straight line, and the positioning groove 16 is disposed right below the third mounting hole 191.
As shown in fig. 4, the fluorescence microscope module includes a long-pass filter 31, an external microscope 32, a liquid lens 33, and a fluorescence light source 34; the fluorescent light source is a ring-shaped UVLED light source, further, the fluorescent light source is a 385nm UVLED light source, the fluorescent light source 34 is disposed on the upper portion of the positioning groove 16 for placing the sample and fixed on the lower surface of the third supporting plate 19, the long pass filter 31 is embedded in the first mounting hole 171, the external lens 32 is embedded in the second mounting hole 181, the liquid lens 33 is embedded in the third mounting hole 191, the focal length of the liquid lens 33 is adjustable, so that the depth of field can be effectively enlarged without moving the sample, a rectangular hole 121 is disposed on the supporting plate 12, the rectangular hole 121 is located between the third supporting plate 19 and the second supporting plate 18, the rectangular hole 121 is used for mounting a liquid lens control system (not shown in the figure), the liquid lens control system is connected to the liquid lens 33 for adjusting the focal length of the liquid lens 33, and the smart phone 2 is provided with fluorescence image processing software.
The utility model relates to a portable fluorescence microscope's that can zoom theory of operation based on smart mobile phone is: the light reflected by the sample placed in the positioning groove 16 irradiated by the fluorescent light source 34 sequentially passes through the liquid lens 33, the external lens 32 and the pass filter 31 and then enters the lens of the smart phone 2, the smart phone 2 captures a fluorescent image of the sample by using the lens, the fluorescent image is processed and analyzed by using fluorescent image processing software, and the processed and analyzed image is displayed on a screen.
In this document, the terms front, back, upper and lower are used to define the components in the drawings and the positions of the components relative to each other, and are used for clarity and convenience of the technical solution. It is to be understood that the use of the directional terms should not be taken to limit the scope of the claims.
The features of the embodiments and embodiments described herein above may be combined with each other without conflict.
The above description is only for the preferred embodiment of the present invention, and is not intended to limit the present invention, and any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention should be included within the protection scope of the present invention.
Claims (8)
1. The utility model provides a portable fluorescence microscope of can zooming based on smart mobile phone which characterized in that: the system comprises a smart phone, a fluorescence microscope module and a bracket; the support comprises an upper base plate, a lower base plate and an accommodating cavity arranged between the upper base plate and the lower base plate, the upper base plate is used for placing the smart phone, a lens hole matched with a lens of the smart phone is formed in the upper base plate, and the lower base plate is used for placing a sample to be tested; a first supporting plate, a second supporting plate and a third supporting plate which are parallel to each other are sequentially arranged in the accommodating cavity from top to bottom, a first mounting hole is formed in the first supporting plate, a second mounting hole is formed in the second supporting plate, a third mounting hole is formed in the third supporting plate, the centers of the first mounting hole, the second mounting hole, the third mounting hole and the lens hole are on the same straight line, and the fluorescence microscope module comprises a long-pass filter, an external double mirror, a liquid lens and a fluorescence light source; the fluorescent light source is arranged above the lower base plate, the long-pass filter is embedded in the first mounting hole, the external double mirror is embedded in the second mounting hole, and the liquid lens is embedded in the third mounting hole.
2. A smartphone-based variable focus portable fluorescence microscope as claimed in claim 1, wherein: the lower base plate is provided with a positioning groove, the positioning groove is formed right below the third mounting hole, and the positioning groove is used for placing a sample.
3. A smartphone-based variable focus portable fluorescence microscope as claimed in claim 1, wherein: three of the four side walls of the accommodating cavity are fixedly arranged supporting plates, and the other side wall is a detachable end cover.
4. A smartphone-based variable focus portable fluorescence microscope as claimed in claim 1, wherein: the inner surface of the containing cavity is coated with a lightproof black aluminum foil.
5. A smartphone-based variable focus portable fluorescence microscope as claimed in claim 1, wherein: the edge of the upper base plate is provided with a raised positioning table, the positioning table is used for positioning the smart phone, and the smart phone is limited in the middle of the positioning table.
6. A smartphone-based variable focus portable fluorescence microscope as claimed in claim 1, wherein: the fluorescent light source is an annular UVLED light source, and the annular UVLED light source is fixed on the lower surface of the third supporting plate.
7. A smartphone-based variable focus portable fluorescence microscope as claimed in claim 1, wherein: the focal length of the liquid lens is adjustable.
8. A smartphone-based variable focus portable fluorescence microscope as claimed in claim 1, wherein: a rectangular hole is formed in a supporting plate on the side face of the accommodating cavity.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920684688.8U CN210072187U (en) | 2019-05-14 | 2019-05-14 | Portable fluorescence microscope of can zooming based on smart mobile phone |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920684688.8U CN210072187U (en) | 2019-05-14 | 2019-05-14 | Portable fluorescence microscope of can zooming based on smart mobile phone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN210072187U true CN210072187U (en) | 2020-02-14 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201920684688.8U Expired - Fee Related CN210072187U (en) | 2019-05-14 | 2019-05-14 | Portable fluorescence microscope of can zooming based on smart mobile phone |
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| CN (1) | CN210072187U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022088422A1 (en) * | 2020-11-02 | 2022-05-05 | 山东大学 | Portable microscope and working method therefor |
-
2019
- 2019-05-14 CN CN201920684688.8U patent/CN210072187U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022088422A1 (en) * | 2020-11-02 | 2022-05-05 | 山东大学 | Portable microscope and working method therefor |
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| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20200214 |