CN209778889U - Biological 3D prints and cultivates integrated device - Google Patents
Biological 3D prints and cultivates integrated device Download PDFInfo
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- CN209778889U CN209778889U CN201822199624.7U CN201822199624U CN209778889U CN 209778889 U CN209778889 U CN 209778889U CN 201822199624 U CN201822199624 U CN 201822199624U CN 209778889 U CN209778889 U CN 209778889U
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- 238000007639 printing Methods 0.000 claims abstract description 110
- 238000010146 3D printing Methods 0.000 claims abstract description 25
- 238000012258 culturing Methods 0.000 claims abstract description 14
- 238000007789 sealing Methods 0.000 claims description 5
- 239000011248 coating agent Substances 0.000 claims description 3
- 238000000576 coating method Methods 0.000 claims description 3
- 210000004204 blood vessel Anatomy 0.000 abstract description 28
- 238000004113 cell culture Methods 0.000 abstract description 6
- 238000010586 diagram Methods 0.000 description 8
- 238000000034 method Methods 0.000 description 7
- 239000007788 liquid Substances 0.000 description 6
- 210000001519 tissue Anatomy 0.000 description 6
- 239000000463 material Substances 0.000 description 5
- 210000004027 cell Anatomy 0.000 description 4
- 210000000056 organ Anatomy 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 3
- 239000000976 ink Substances 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 230000017531 blood circulation Effects 0.000 description 2
- 230000004087 circulation Effects 0.000 description 2
- 230000005484 gravity Effects 0.000 description 2
- 231100000252 nontoxic Toxicity 0.000 description 2
- 230000003000 nontoxic effect Effects 0.000 description 2
- 230000000149 penetrating effect Effects 0.000 description 2
- 239000012466 permeate Substances 0.000 description 2
- 238000009825 accumulation Methods 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 238000009833 condensation Methods 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- 210000002889 endothelial cell Anatomy 0.000 description 1
- 210000002950 fibroblast Anatomy 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 238000010030 laminating Methods 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000001172 regenerating effect Effects 0.000 description 1
- 210000000329 smooth muscle myocyte Anatomy 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- 210000002993 trophoblast Anatomy 0.000 description 1
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The embodiment of the utility model provides a biological 3D printing and culturing integrated device, which comprises a temperature control platform and a printing groove, wherein bearing seats are respectively arranged at two sides of the printing groove, a first connecting rod and a second connecting rod are respectively arranged in the two bearing seats, a first through hole is arranged at one end of the first connecting rod, a biological needle head is fixed at the outlet of the first through hole, the biological needle head passes through one bearing seat and is arranged in the printing groove, and the other end of the first connecting rod is connected with a motor; a biological needle is fixed at the outlet of the first through hole, and a biological needle is also fixed at the outlet of the second through hole. When 3D printed the beginning, two motors ran simultaneously, and the blood vessel on the biological syringe needle can rotate, and the outside shower nozzle of printing of cooperation can guarantee that the blood vessel surface obtains comprehensive, rapid printing. The temperature control platform is arranged at the bottom of the printing groove, so that the temperature in the printing groove is kept within a set range. And realizing continuous constant-temperature cell culture of the printed blood vessel after the biological 3D printing is finished.
Description
Technical Field
The embodiment of the utility model provides a biological three-dimensional printing technical field especially relates to a biological 3D prints and cultivates integrated device.
Background
a biological 3D printing apparatus is a technique manufactured by accumulating biological materials, which is an apparatus for manufacturing living tissues or organs using biological cells or building blocks to layer-cumulatively stack materials as needed on the basis of a digitized file. Different from the traditional additive manufacturing technology, the printing material of the biological 3D printing technology is not easy to prepare, and has strict requirements on the environment during and after printing, and usually requires a culture solution environment which is nontoxic and has a certain temperature meeting certain requirements. An important application scenario of the technology is to solve the problem of tissue and organ regrooving in the traditional regenerative medical field and manufacture a transplantable organ meeting the requirements for human organ transplantation.
Most of the existing biological printing devices are built based on three-axis motion assemblies, and can only accumulate on a plane layer. A small number of existing devices try to use more degrees of freedom to accumulate in space, but because the printing target is mostly fixed in a small culture environment, the surface of the printing target is difficult to be covered comprehensively due to object interference, and how to enable the whole surface of the printing target to be printed quickly is a difficult point of research in the field. In addition, the conventional bioprinting apparatus does not control different culture temperatures to culture different target tissues after printing different target tissue cells.
SUMMERY OF THE UTILITY MODEL
The above-mentioned shortcomings of conventional biological 3D printing devices are addressed. The embodiment of the utility model provides a biological 3D prints and cultivates integrated device.
The embodiment of the utility model provides a biological 3D printing and culturing integrated device, which comprises a temperature control platform and a printing groove;
The printing groove is fixedly arranged on the upper surface of the temperature control platform, bearing seats are respectively arranged on two sides of the printing groove, a first connecting rod and a second connecting rod are respectively arranged in the two bearing seats, a first through hole is formed in one end of the first connecting rod, a biological needle is fixed at the outlet of the first through hole, penetrates through one bearing seat and is arranged in the printing groove, and the other end of the first connecting rod is connected with a motor; a biological needle is fixed at the outlet of the first through hole;
A second through hole is formed in one end of the second connecting rod, the second connecting rod penetrates through the other bearing seat and is arranged in the printing groove, the other end of the second connecting rod is connected with the motor, and a biological needle is fixed at the outlet of the second through hole.
the printing device comprises a printing groove body, a temperature control platform, a printing groove body and a printing device, wherein a first threaded hole is formed in the bottom of the printing groove body, a second threaded hole is formed in the upper surface of the temperature control platform, the first threaded hole and the second threaded hole are arranged oppositely, and the temperature control platform is connected with the printing groove body through threads.
Wherein, the one end of first through-hole is equipped with the internal thread, the other end of first through-hole is located first connecting rod, and the perpendicular to first cavity post has been seted up to first connecting rod.
The one end of second through-hole is equipped with the internal thread, the other end of second through-hole is located in the second connecting rod, and the perpendicular to second cavity post has been seted up to the second connecting rod, first cavity post with second cavity post is connected through the hose.
Wherein, round holes are arranged on two sides of the printing groove;
the bearing frame includes drum and square column, the drum passes round hole and vertical fixation are in the bottom surface of square column, the bottom surface of square column is fixed in the lateral surface of printing the groove, the bearing has been placed in the drum, the outside of bearing is equipped with the oil blanket.
The printing groove is provided with a plurality of third threaded holes around the round hole, the corresponding position of the square column and the contact surface of the printing groove is provided with a fourth threaded hole, and the square column is connected with the printing groove through a screw.
and a sealing ring is arranged at the joint of the bearing seat and the printing groove.
Wherein, print slot upper portion for wide down narrow down's trapezoidal recess of falling.
Wherein, the side bottom of printing the groove has seted up the cylinder through-hole.
Wherein, the surface of the printing groove is plated with a layer of coating film.
The bottom of the printing groove is provided with a rectangular assembly groove, the upper surface of the temperature control platform is provided with a groove, and the rectangular assembly groove is fixed in the groove.
The embodiment of the utility model provides a biological 3D prints and cultivates integrated device prints two biological syringe needles that are used for connecting blood vessel that the inslot was arranged to set up relatively, and two biological syringe needles are fixed respectively in the one end of first connecting rod and second connecting rod, and first connecting rod and second connecting rod connect a motor separately. When 3D prints and begins, two motors move simultaneously, and the blood vessel on the biological syringe needle can rotate, and the cooperation outside printing shower nozzle of multi freedom can guarantee that the blood vessel surface obtains comprehensive, rapid printing. The embodiment of the utility model provides a through set up temperature control platform at print tank bottom, make the temperature of printing the inslot keep in the settlement within range. And realizing continuous constant-temperature cell culture of the printed blood vessel after the biological 3D printing is finished.
drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed to be used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.
Fig. 1 is a schematic structural diagram of an integrated biological 3D printing and culturing device provided according to an embodiment of the present invention;
fig. 2 is a schematic structural diagram of a printing slot according to an embodiment of the present invention;
Fig. 3 is a schematic structural diagram of a temperature control platform according to an embodiment of the present invention;
Fig. 4 is a schematic structural diagram of a first connecting rod according to an embodiment of the present invention;
In the figure, 1, a cylindrical through hole; 2. a first threaded hole; 3. a bevel; 4. a third threaded hole; 5. a circular hole; 6. a rectangular assembly groove; 7. a first link; 8. a second hollow column; 9. a biological needle; 10. a bearing seat; 11. a second threaded hole; 12. a temperature control platform; 13. a second link; 14. a first hollow column; 15. a fourth threaded hole; 16. a first through hole; 17. a cylinder; 18. a square column.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.
It is noted that, in the description of the embodiments of the present invention, relational terms such as first and second, and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. The terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other identical elements in a process, method, article, or apparatus that comprises the element. The terms "upper", "lower", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience in describing the present invention and simplifying the description, but do not indicate or imply that the referred devices or elements must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as limiting the present invention. Unless expressly stated or limited otherwise, the terms "mounted," "connected," and "connected" are intended to be inclusive and mean, for example, that they may be fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood according to specific situations by those skilled in the art.
Because most of the existing biological printing devices are built based on three-axis motion components, accumulation can be carried out on a plane layer only. A few of the prior art devices attempt to use more degrees of freedom to accumulate in space, but because the printed object is mostly fixed within a small incubation environment. Due to the interference of objects, the existing biological printing device is difficult to achieve full coverage when printing the target surface. In addition, the conventional bioprinting apparatus does not control different culture temperatures to culture different target tissues after printing different target tissue cells.
Therefore, the embodiment of the utility model provides a biological 3D prints and cultivates integrated device through arranging two biological syringe needles that are used for connecting the blood vessel that set up relatively in printing the inslot, and two biological syringe needles are fixed respectively in the one end of first connecting rod and second connecting rod, and first connecting rod and second connecting rod connect a motor separately. When 3D prints and begins, two motors move simultaneously, and the blood vessel on the biological syringe needle can rotate, and the cooperation outside printing shower nozzle of multi freedom can guarantee that the blood vessel surface obtains comprehensive, rapid printing. The embodiment of the utility model provides a through set up temperature control platform at print tank bottom, make the temperature of printing the inslot keep in the settlement within range. And realizing continuous constant-temperature cell culture of the printed blood vessel after the biological 3D printing is finished.
Biological 3D printing is performed layer by layer with different biological inks, from endothelial cells, smooth muscle cells to fibroblasts, continuously infiltrating and nourishing each cell layer by a layer of special condensation material on the print bar.
Fig. 1 is a schematic structural diagram of a biological 3D printing and culturing integrated device provided according to an embodiment of the present invention, and as shown in fig. 1, the device includes a temperature control platform 12 and a printing slot. Print groove fixed mounting in the upper surface of temperature control platform 12, the laminating of the bottom surface in temperature control platform 12's upper surface and printing groove, temperature control platform 12 controls the liquid temperature in the printing groove through the form of metal heat-conduction. In this embodiment, the printing groove is made of a material with a low specific heat capacity, so that the temperature in the printing groove can be conveniently controlled. The temperature in the printing tank is kept within a set range by arranging a temperature control platform 12 at the bottom of the printing tank. After biological 3D printing is completed, constant temperature cell culture can be continuously performed on the printed blood vessels.
Bearing seats 10 are respectively installed on two sides of the printing groove, a first connecting rod 7 and a second connecting rod 13 are respectively arranged in the two bearing seats 10, a first through hole 16 is formed in one end of the first connecting rod, a biological needle 9 is fixed at the outlet of the first through hole 16 and penetrates through one bearing seat 10 to be arranged in the printing groove, and the other end of the first connecting rod 7 is connected with a motor; a biological needle 9 is fixed at the outlet of the first through hole 16. A second through hole is formed in one end of the second connecting rod 13, the second through hole penetrates through the other bearing seat 10 and is arranged in the printing groove, the other end of the second connecting rod 13 is connected with a motor, and a biological needle 9 is fixed at the outlet of the second through hole.
specifically, referring to fig. 1, a printing slot is installed at both sides thereof with a bearing housing 10, respectively. One end of the first connecting rod 7 is arranged in the printing slot by penetrating through a bearing seat 10 at one side of the printing slot, and the other end is connected with a motor (not shown in the figure); one end of the second connecting rod 13 is arranged in the printing slot by penetrating through the other bearing seat 10, and the other end is connected with another motor (not shown in the figure); one end of the first connecting rod 7 is provided with a first through hole 16, one end of the second connecting rod 13 is provided with a second through hole, and a biological needle 9 is fixed at the outlet of the first through hole 16 and the outlet of the second through hole. Wherein, two biological needles 9 are oppositely arranged in the printing groove and are used for connecting blood vessels.
it should be noted that, the bio-ink should be able to permeate on the surface of the blood vessel, the trophoblast layer should depend on gravity, and when the included angle between the normal vector of the printing position and the vertically upward vector is larger than the maximum printing angle, the bio-ink cannot permeate. In this embodiment, the blood vessel is fixed in printing the inslot through biological syringe needle 9 level, can guarantee to print the operation in the certain angle within range of blood vessel top, when beginning 3D to print, the motor operation drives first connecting rod 7 and second connecting rod 13 and rotates, and then makes the blood vessel rotation on the biological syringe needle 9, and every position that the outside multi freedom of cooperation printed the shower nozzle and can guarantee the blood vessel surface can all carry out comprehensive, rapid printing.
The embodiment of the utility model provides a biological 3D prints and cultivates integrated device through arranging two biological syringe needles that are used for connecting blood vessel that set up relatively in printing the inslot, and two biological syringe needles are fixed respectively
The first connecting rod and the second connecting rod are respectively connected with a motor. When 3D prints and begins, two motors move simultaneously, and the blood vessel on the biological syringe needle can rotate, and the cooperation outside printing shower nozzle of multi freedom can guarantee that the blood vessel surface obtains comprehensive, rapid printing. The embodiment of the utility model provides a through set up temperature control platform at print tank bottom, make the temperature of printing the inslot keep in the settlement within range. And realizing continuous constant-temperature cell culture of the printed blood vessel after the biological 3D printing is finished.
Fig. 2 is a schematic structural diagram of a printing slot according to the embodiment of the present invention, and fig. 3 is a schematic structural diagram of a temperature control platform 12 according to the embodiment of the present invention. Reference is made to fig. 1, 2 and
Fig. 3 shows that a first threaded hole 2 is formed in the bottom of the printing groove body, a second threaded hole is formed in the upper surface of the temperature control platform 12, the first threaded hole 2 and the second threaded hole are oppositely arranged, and the temperature control platform 12 is connected with the printing groove through threads.
further, the bottom of the printing groove is provided with a rectangular assembly groove 6, the upper surface of the temperature control platform 12 is provided with a groove, and the rectangular assembly groove 6 is fixed in the groove.
Fig. 4 is a schematic structural diagram of the first connecting rod according to the embodiment of the present invention, referring to fig. 1 and 4, one end of the first through hole 16 is provided with an internal thread, the other end of the first through hole 16 is located in the first connecting rod 7, and a first hollow column 14 is disposed perpendicular to the first connecting rod 7.
The structure of second connecting rod 13 is the same with first connecting rod 7, and wherein, the one end of second through-hole is equipped with the internal thread, the other end of second through-hole is located in second connecting rod 13, and the perpendicular to second connecting rod 13 has seted up second cavity post 8, first cavity post 14 with second cavity post 8 is connected through the hose.
Specifically, one end of the first through hole 16 is provided with an internal thread for connecting the biological needle 9, the other end of the first through hole 1610 is located in the first link 7, and the other end of the first through hole 16 is perpendicular to the first link 7 and is provided with a first hollow column 14. It should be noted that the first hollow column 14 and the second hollow column 8 are connected by a hose.
Blood flows in the blood vessel, the flexible tube, the first hollow column 14 and the biological needle 9, forming a closed circulation simulating blood flow. The blood vessel is horizontally arranged between the two biological needles 9, so that circulation can be ensured without being influenced by gravity.
On the basis of the above embodiments, referring to fig. 1 and 2, circular holes 5 are formed in two sides of the printing groove, the bearing seat 10 includes a cylinder 17 and a square column 18, the cylinder 17 penetrates through the circular holes 5 and is vertically fixed to the bottom surface of the square column 18, the bottom surface of the square column 18 is fixed to the outer side surface of the printing groove, a bearing is placed in the cylinder 17, and an oil seal is arranged on the outer side of the bearing.
Specifically, round holes 5 are opened at both sides of the printing slot for fixing the bearing seat 10. The bearing seat 10 comprises a cylinder 17 and a square column 18, the cylinder 17 penetrates through the round hole 5 of the bearing seat 10 and is vertically fixed on the bottom surface of the square column 18, the bottom surface of the square column 18 is fixed on the outer side surface of the printing groove, a bearing is placed in the cylinder 17, and a connecting rod is placed in the bearing. Wherein, the outside of the bearing is provided with an oil seal for preventing the inner ring of the bearing seat 10 from leaking liquid.
On the basis of the above embodiments, referring to fig. 1 and 2, a plurality of third threaded holes 4 are opened around the round hole 5 of the printing slot, a fourth threaded hole 15 is opened at a position corresponding to the contact surface of the square column 18 and the printing slot, and the square column 18 and the printing slot are connected by screws.
Preferably, a sealing ring is arranged at the joint of the bearing seat 10 and the printing groove. When the bearing seat 10 is fixed with the printing groove by using screws, a sealing ring with a small hole is padded, and the sealing ring and an oil seal arranged in the bearing seat 10 play a role in preventing liquid leakage.
On the basis of the above embodiments, referring to fig. 1 and 2, in the present embodiment, the upper portion of the printing slot is an inverted trapezoidal groove with a wide top and a narrow bottom. Print groove upper portion and set up to wide down narrow trapezoidal groove structure down, liquid flows down from the inclined plane 3 of printing the groove, can guarantee to print the spout route of the printing shower nozzle of groove top not influenced to practice thrift and add the liquid of printing the inslot.
On the basis of the above embodiments, the bottom end of the side surface of the printing tank is provided with a cylindrical through hole 1 for replacing the liquid in the printing tank.
On the basis of the above embodiments, the surface of the printing slot is plated with a coating film. In the embodiment, the surface of the printing groove is coated with the anticorrosive and non-toxic material, so that the safety of the device is improved.
The embodiment of the utility model provides a biological 3D prints and cultivates integrated device prints two biological syringe needles that are used for connecting blood vessel that the inslot was arranged to set up relatively, and two biological syringe needles are fixed respectively in the one end of first connecting rod and second connecting rod, and first connecting rod and second connecting rod connect a motor separately. When 3D prints and begins, two motors move simultaneously, and the blood vessel on the biological syringe needle can rotate, and the cooperation outside printing shower nozzle of multi freedom can guarantee that the blood vessel surface obtains comprehensive, rapid printing. The embodiment of the utility model provides a through set up temperature control platform at print tank bottom, make the temperature of printing the inslot keep in the settlement within range. And realizing continuous constant-temperature cell culture of the printed blood vessel after the biological 3D printing is finished.
Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it should be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; such modifications and substitutions do not depart from the spirit and scope of the present invention in its corresponding aspects.
Claims (10)
1. a biological 3D printing and culturing integrated device is characterized by comprising a temperature control platform and a printing groove;
The printing groove is fixedly arranged on the upper surface of the temperature control platform, bearing seats are respectively arranged on two sides of the printing groove, a first connecting rod and a second connecting rod are respectively arranged in the two bearing seats, a first through hole is formed in one end of the first connecting rod, a biological needle is fixed at the outlet of the first through hole, penetrates through one bearing seat and is arranged in the printing groove, and the other end of the first connecting rod is connected with a motor;
A second through hole is formed in one end of the second connecting rod, the second connecting rod penetrates through the other bearing seat and is arranged in the printing groove, the other end of the second connecting rod is connected with the motor, and a biological needle is fixed at the outlet of the second through hole.
2. The biological 3D printing and culturing integrated device according to claim 1, wherein a first threaded hole is formed in the bottom of the printing groove, a second threaded hole is formed in the upper surface of the temperature control platform, the first threaded hole and the second threaded hole are oppositely arranged, and the temperature control platform is connected with the printing groove through threads.
3. the biological 3D printing and culturing integrated device according to claim 1, wherein one end of the first through hole is provided with an internal thread, the other end of the first through hole is positioned in the first connecting rod, and a first hollow column is arranged perpendicular to the first connecting rod;
the one end of second through-hole is equipped with the internal thread, the other end of second through-hole is located in the second connecting rod, and the perpendicular to second cavity post has been seted up to the second connecting rod, first cavity post with second cavity post is connected through the hose.
4. The biological 3D printing and culturing integrated device according to claim 1, wherein round holes are formed on two sides of the printing groove;
The bearing frame includes drum and square column, the drum passes round hole and vertical fixation are in the bottom surface of square column, the bottom surface of square column is fixed in the lateral surface of printing the groove, the bearing has been placed in the drum, the outside of bearing is equipped with the oil blanket.
5. The biological 3D printing and culturing integrated device according to claim 4, wherein a plurality of third threaded holes are formed around the round hole of the printing groove, fourth threaded holes are formed at positions of the square column corresponding to the contact surface of the printing groove, and the square column is connected with the printing groove through screws.
6. The biological 3D printing and culturing integrated device according to claim 4, wherein a sealing ring is arranged at the joint of the bearing seat and the printing groove.
7. The biological 3D printing and culturing integrated device according to claim 1, wherein the upper part of the printing groove is an inverted trapezoidal groove which is wide at the top and narrow at the bottom.
8. The biological 3D printing and culturing integrated device according to claim 1 or 7, wherein a cylindrical through hole is formed at the bottom end of the side surface of the printing groove.
9. The integrated biological 3D printing and culturing device according to claim 1, wherein the surface of the printing slot is coated with a coating.
10. The biological 3D printing and culturing integrated device according to claim 1, wherein a rectangular assembly groove is formed in the bottom of the printing groove, a groove is formed in the upper surface of the temperature control platform, and the rectangular assembly groove is fixed in the groove.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201822199624.7U CN209778889U (en) | 2018-12-26 | 2018-12-26 | Biological 3D prints and cultivates integrated device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201822199624.7U CN209778889U (en) | 2018-12-26 | 2018-12-26 | Biological 3D prints and cultivates integrated device |
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| CN209778889U true CN209778889U (en) | 2019-12-13 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111423981A (en) * | 2020-04-30 | 2020-07-17 | 海口健康岛生物科技有限公司 | High-purity stem cell culture automation equipment |
| CN113085175A (en) * | 2021-02-24 | 2021-07-09 | 张爱玲 | Tubular 3D biological printing typical process platform device |
-
2018
- 2018-12-26 CN CN201822199624.7U patent/CN209778889U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111423981A (en) * | 2020-04-30 | 2020-07-17 | 海口健康岛生物科技有限公司 | High-purity stem cell culture automation equipment |
| CN113085175A (en) * | 2021-02-24 | 2021-07-09 | 张爱玲 | Tubular 3D biological printing typical process platform device |
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