CN209727783U - Accurate focusing mechanism for digital slices scanner - Google Patents
Accurate focusing mechanism for digital slices scanner Download PDFInfo
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- CN209727783U CN209727783U CN201920355741.XU CN201920355741U CN209727783U CN 209727783 U CN209727783 U CN 209727783U CN 201920355741 U CN201920355741 U CN 201920355741U CN 209727783 U CN209727783 U CN 209727783U
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Abstract
The utility model discloses a kind of accurate focusing mechanisms for digital slices scanner.The utility model includes displacement platform, thrust bindiny mechanism, lever mechanism, thimble and E shape fixed frame;Displacement platform includes voice coil motor, crossed roller guide rail and mounting plate;Thrust bindiny mechanism is made of the thrust plate for being mounted on displacement platform with a rectangular elastic piece;Lever mechanism includes lever stock, lever quarter butt, lever supporting plate and strip elastic piece;Thimble is a ball;E shape fixed frame is used for scanning constant light source, preview light source, micro- optical path and motion platform.The utility model can provide two close movements up and down for the auto-focusing process in imaging process, obtain clearly image.Applied to histocyte observation, remote pathological diagnosis, Teaching of Pathology and expert discussion.
Description
Technical field
The utility model relates to a kind of accurate focusing mechanisms, and in particular to a kind of precision for digital slices scanner is right
Coke installation.Digital slices scanner auto-focusing, microscope imaging, clinical medicine diagnosis, life science and pathology religion
Etc. fields.
Background technique
Digital slices scanner is a kind of dress gathering high-speed motion platform, microoptic and computer technology and being integrated
It sets.Different from traditional microscope, it shoots the tissue under multiple and different visuals field by the mobile physics slice of high-speed motion platform
Cell image.It recycles computer technology that the cell image of shooting is carried out image mosaic and generates the number with complete Pathological Information
Word sectioning image.Generally speaking, digital slices scanner is a kind of by entire glass slide full information, comprehensive quick scanning, is made
The glass slide of conventional matter becomes the device of new-generation digital pathological section.
With the development of network and computer technology, increasingly maturation, the digital picture of image processing techniques are gradually applied
In various fields.The digital picture that robot is shot by machine vision carries out the positioning of workpiece, in non-destructive testing, passes through number
The face shape situation of the phase interference observation workpiece of word image.Digital picture, which is removed, to be applied in industry, is also increasingly being applied to
In medical diagnosis and pathology.The digital slices image scanned by network transmission, expert can remotely beg for difficult and complicated illness
By progress clinical medicine diagnosis.By the cell situation on observation slice, life science can be carried out.The number of generation is cut
Piece can be detached from indispensable micro- sem observation since its is reproducible and remote transmission characteristic, be used for Teaching of Pathology.Facilitate religion
It learns, reduces cost of equipment, solve the problems, such as common equipment deficiency.
But since different cell size thickness are different, same cells are also possible to of different sizes, and the physics of production is caused to be cut
Piece or cell smear Chang Houdu are inconsistent.For fixed-focus away from microcobjective for, can because slice not occur in focus
The blurred image phenomenon of digital slices.It is therefore desirable to develop a kind of autofocus for digital slices scanning means,
It realizes the accurate scan being sliced to physics, takes clearly digital slices image.
Existing auto focusing method has and utilizes image coherent approach.Clear figure is calculated according to the image that two width obscure
The focal position of picture and clearly image pattern.But this method is very high for the configuration requirement of equipment, simultaneously because to locate
A large amount of image data is managed, focusing speed is extremely slow.Another method is specially to be equipped with corresponding autofocus, auxiliary slice
It is focused imaging.But due to micro-imaging, the size in the single visual field is only 1.1mm or so, and is entirely sliced region to be scanned
For 75mm*55mm.Therefore need high response frequency, speed and kinematic accuracy.Existing motion platform is often since itself is transported
Dynamic precision is micron order, can not directly provide automatic focus movement.Voice coil motor cooperates high-precision grating sensor combination thick stick
Linkage, which is realized, controls the precision of micro- focusing.
The utility model supports the wound such as pathological section towards the demand, by voice coil motor displacement platform combination lever mechanism
New design, develops a kind of accurate focusing device for digital slices scanner.It can accurate control physics slice by the device
Up and down motion, realize slice scanning process in automatic focusing.To the digital slices of shooting clear, examined for clinical treatment
It is disconnected, Teaching of Pathology etc..
Summary of the invention
The purpose of this utility model is for digital slices scanner, microscope imaging, clinical medicine diagnosis, life science
For the occasions such as research and Teaching of Pathology to the application demand of accurate focal imaging, designing one kind can drive glass slide to realize up and down
The autofocus of direction precise motion.Simultaneously the device have the function of mechanical position limitation, can be digital slices it is clear at
As providing a certain range of precise motion.
In order to achieve the above objectives, the utility model adopts the following technical solution is resolved:
For the accurate focusing mechanism of digital slices scanner, including displacement platform, thrust bindiny mechanism, lever mechanism,
Thimble and E shape fixed frame:
Displacement platform includes voice coil motor, crossed roller guide rail and mounting plate;Thrust bindiny mechanism is flat by being mounted on displacement
The thrust plate of platform and a rectangular elastic piece form;Lever mechanism includes lever stock, lever quarter butt, lever supporting plate and strip bullet
Property piece;Thimble is a ball;E shape fixed frame is used for scanning constant light source, preview light source, micro- optical path and motion platform, specifically
:
Motor mount (201) fixed voice coil motor (207) is on E shape fixed frame 213, the movement of voice coil motor (207)
Part is connect with thrust plate, and electromechanics position limiting structure is provided between thrust plate, motor mount (201) and thrust plate
(205) moving displacement of cooperation limitation voice coil motor (207);Crossed roller guide rail (204) be fixed on motor mount (201) with
On thrust plate (205), crossed roller guide rail (204) side is connect with motor fixing seat, and the other side is connect with thrust plate (205),
The movement of voice coil motor (207) will drive the movement of thrust plate, and crossed roller guide rail will guarantee the depth of parallelism and verticality of movement;
Grating sensor (203) and its corresponding reading head, real time monitoring feedback voice coil motor are installed on crossed roller guide rail (204)
(207) moving displacement;The thrust plate is a L shape, and one end and voice coil motor move side and connect, the other end respectively with intersect
Roller movement side and the connection of rectangular elastic piece;Thrust plate is moved with voice coil motor (207), is crossed roller guide rail, grating sensing
Device and lever mechanism provide movement;Threaded hole on thrust plate (205) and motor mount (201) cooperates, and passes through screw, spring
Realize the limit moved to voice coil motor (207);Rectangular elastic piece (206) activation lever stock (208) movement, lever stock
(208) effect of the one end by the elastic-restoring force of strip elastic piece, stop motion;Simultaneously lever quarter butt (211) due to by
To the effect of elastic force, the movement opposite with lever stock one end direction of motion is generated;Drive the thimble on lever quarter butt (211)
(212) it moves, driving physics glass slice, which moves up and down, realizes accurate focus.
Lever mechanism specifically includes rectangular elastic piece (206), lever stock (208), lever supporting plate (219), strip bullet
Property piece (210), rectangular minipad (214), lever quarter butt (211), thimble (212);The lever stock (208) passes through rectangular bullet
Property piece (206) the connection of two through-holes on the thrust plate of displacement platform;There are four logical above for the rectangular elastic piece (206)
Hole;Two through hole is used to connect the thrust plate of displacement platform, and in addition two through hole is for connecting lever stock.
The thrust plate is a L shape thrust plate, and one end and voice coil motor movement side are connect, and the other end is rolled with intersecting respectively
Son movement side and the connection of rectangular elastic piece.Thrust plate is crossed roller guide rail, grating sensor and lever mechanism with motor movement
Movement is provided.Threaded hole cooperation on threaded hole and motor mount on thrust plate simultaneously, is realized by screw, spring to electricity
The limit of machine movement.
The rectangular elastic piece respectively connected thrust plate and lever stock, and the thrust of transmitting thrust plate is become by itself
Shape provides power for lever mechanism.The rectangular elastic piece includes but is not limited to the materials such as spring steel, stainless steel substrates.
The lever mechanism is made of lever stock, strip elastic piece, lever quarter butt and lever support.Lever stock
One end has two threaded holes to connect with rectangular elastic piece, and the other end of lever stock is connect by strip elastic piece with lever quarter butt
Transmit power.Strip elastic piece is fixed on lever supporting plate, and lever supporting plate truck dead lever mechanism is in E shape fixed plate.Lever
Stock is a long T-bar, and lever quarter butt is also a T-bar.Lever stock has threaded hole to match with the threaded hole in E shape fixed plate
It closes, realizes the limit to move up and down to glass slide.
There is a big unthreaded hole in one end of the lever quarter butt, with micro- light path coaxial, guarantees that imaging ray passes through micro- object
Mirror images in scanning camera.There are a semi-spherical grooves close to edge in circular hole, for installing fixed thimble.
The long quarter butt size of the lever mechanism is at certain ratio, for scaling the thimble of stock one end Yu quarter butt one end
Moving displacement.Kinematic error has also been scaled simultaneously, improves focusing precision.Strip elastic piece combination lever fixed supported slab passes through certainly
The transmitting of moving displacement between lever stock and lever quarter butt is realized in body deformation.
The thimble protrudes lever quarter butt surface about 1.5mm, the following table face contact with physics slice, support physics slice
It moves up and down.The thimble includes the materials such as ruby, silicon nitride, ceramics, stainless steel, and the utility model preferentially uses ruby
Material.
The lower part fixed light source of E shape fixed frame and voice coil motor motion platform, wherein voice coil motor displacement platform fixing seat
It is fixed on the back side of E shape fixed frame.The middle part truck dead lever supporting plate and preview part of the E shape fixed frame, transmission force and movement.
The square hole of certain altitude is provided in the middle part of the E shape plate, for realizing the up and down motion of lever mechanism by lever stock.E shape
The fixed microcobjective in the top of plate, scanning camera and its optical path, realize the machine of entire digital slices scanning means optical texture
Tool design, and required modules are become one, realize the Integration Design of micro- optical path.
The physics slice is translatable in X/Y plane, is moved up and down by voice coil motor activation lever mechanism, the long quarter butt of lever leads to
Dimension scale scaling moving displacement passing movement is crossed, precise motion above and below the thimble driving glass slide on lever quarter butt.
The accurate focusing mechanism has in limit range, in the operating mode and limit range moved upwards, transports downwards
Two kinds of dynamic operating modes.
The accurate focusing mechanism is in limit range, the operating mode that moves upwards: voice coil motor, which drives, intersects rolling
Sub- guide rail moves downward, and lever stock also moves downward therewith.The other end of lever stock is due to the work by elastic restoring force
With activation lever quarter butt moves upwards.Thus the thimble on lever quarter butt also moves upwards therewith, and driving glass slide is also transported upwards
It is dynamic, realize automatic focus.
The accurate focusing mechanism is in limit range, the operating mode that moves downward: voice coil motor, which drives, intersects rolling
Sub- guide rail moves upwards, and lever stock also moves upwards therewith.The other end of lever stock is due to the work by elastic restoring force
With activation lever quarter butt moves downward.Thus the thimble on lever quarter butt also moves downward therewith, and driving glass slide is also transported downwards
It is dynamic, realize automatic focus.
The utility model having the beneficial effect that compared with the existing technology
First, the utility model can provide the close focusing for digital slices scanner, change previous digital slices
The fogging image generated by focusing problem, or even fuzzy situation;Second, close focusing mechanism provided by the utility model
With multiple-working mode, both accurate focusing can be realized with driving glass slide movement, and can also move upwards adjustment glass slide
The depth of parallelism, produce clearly digital slices image, carry out cell observation, ground applied to clinical medicine diagnosis, life science
Study carefully with Teaching of Pathology etc..
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the lever mechanism of the utility model embodiment;
Fig. 2 is the accurate autofocus structural schematic diagram of the utility model embodiment;
Fig. 3 is the application framework figure of the driving glass slide automatic focusing of the utility model embodiment;
Fig. 4 be the utility model embodiment driving glass slide to restraining position operation schematic diagram;
Specific embodiment
The utility model is illustrated with reference to the accompanying drawings and examples.
The embodiments of the present invention are related to a kind of autofocus for digital slices scanner, and there is driving to carry
The operating mode that slide moves up and down, focuses automatically, can be used for the automatic focusing of digital slices scanner, microscope imaging.It is raw
At clearly digital picture for fields such as clinical medicine diagnosis, life science and Teaching of Pathology.
For the accurate focusing mechanism of digital slices scanner, including displacement platform, thrust bindiny mechanism, lever mechanism,
Thimble and E shape fixed frame.Displacement platform includes voice coil motor, crossed roller guide rail and mounting plate;Thrust bindiny mechanism is by installing
It is formed in the thrust plate of displacement platform and a rectangular elastic piece;Lever mechanism include lever stock, lever quarter butt, lever supporting plate with
Strip elastic piece;Thimble is a ball;E shape fixed frame is flat for scanning constant light source, preview light source, micro- optical path and movement
Platform is integral.
Wherein core institution is lever mechanism as shown in Figure 1, including rectangular elastic piece, lever stock, lever supporting plate, strip
Shape elastic piece, rectangular minipad, lever quarter butt, thimble (212).The lever stock is connected by two through-holes of rectangular elastic piece
It connects on the thrust plate with displacement platform.There are four through-holes above the rectangular elastic piece.Two through hole is for connecting displacement platform
Thrust plate, in addition two through hole is for connecting lever stock.The materials such as spring steel, stainless steel substrates can be used in the rectangular elastic piece,
The utility model preferentially uses spring steel.Spring leaf used in the utility model with a thickness of 0.35mm, long 18mm, wide 22.5mm.
The lever stock is a long T-shaped structure.There is the threaded hole of two tapped through holes Yu lever quarter butt head in T forming head portion
It matches, realizes the connection of lever stock and lever quarter butt.A through-hole is provided on lever stock, by the through-hole and admittedly
Threaded hole cooperation on fixed board, realizes the limitation being displaced to lever motion.The long 175mm of lever stock that the utility model uses,
Width is respectively 18mm and 34mm, high 9mm.Using aluminum alloy materials, surface blackening processing.
The lever supporting plate is a rectangular Al alloy block for being internally provided with central symmetry U-type groove.Its upper surface is provided with one
Threaded hole, for lever supporting plate is fixed on a mounting board.Its side is provided with a threaded hole, for fixing strip elastic piece,
And the flank threads hole lower end is equipped with step, for positioning rectangular minipad.There are four through-holes on strip elastic piece, respectively
Lever stock and lever quarter butt are connected, the effect of fixed strip elastic piece is cooperated with lever supporting plate threaded hole.The utility model
The strip elastic piece of use, long 50mm, width 6mm, thickness 0.2mm.Stainless steel substrates, aluminium flake, spring can be used in strip elastic piece
The materials such as steel disc.The utility model preferentially uses spring steel plate.
The rectangular minipad is provided with central through hole, the fixed strip elastic piece of matching thread.
The lever quarter butt structure in T shape, the threaded hole on T shape both sides are used to connect lever by strip elastic piece long
Bar.One end of the strip of lever quarter butt is provided with centrosymmetric unthreaded hole, for through the light through glass slice, imaging
In microcobjective.In strip one end of lever quarter butt, there is a hemispherical circular groove for fixing thimble (212).
The ratio of the utility model lever quarter butt and lever stock is 1 to 7, and applies thrust in one end of lever stock,
One end of lever quarter butt drives glass slice.According to geometrical relationship approximation, the height of slide movement and the movement of displacement platform can be obtained
Degree is than being 1:7.Thus movement range is reduced, kinematic error is reduced, improves kinematic accuracy.
Fig. 2 shows the structural schematic diagram of the accurate focusing mechanism 200 for digital slices scanner, precision focusing dress
It sets including motor mount 201, voice coil motor 207, reading head and its mounting base 202, grating scale 203, crossed roller guide rail
204, thrust plate 205, rectangular elastic piece 206, lever stock 208, lever supporting plate 209, strip elastic piece 210, lever quarter butt
211, thimble 212 and E shape fixed frame 213.Motor is fixedly mounted on E shape fixed frame 213, with thrust plate in motor mount 201
The moving displacement of 205 cooperation limiting motors 207.Crossed roller guide rail 204 is fixed on motor mount 201 and thrust plate 205,
Steady, uniform power is provided for the movement of thrust plate 205.Grating sensor 203 is installed on crossed roller guide rail 204, it is real
When monitoring feedback voice coil motor 207 moving displacement.Threaded hole on thrust plate 205 and motor mount 201 cooperates, realization pair
The control of 207 moving displacement of voice coil motor.Rectangular 206 activation lever stock 208 of elastic piece movement, lever stock one end is grown
The effect of the elastic-restoring force of bar shaped elastic piece power, stop motion.Lever quarter butt 211 is due to the effect by elastic force simultaneously,
Generate the movement opposite with lever stock one end direction of motion.It drives the thimble 212 on lever quarter butt to move, drives physics glass
Slice, which moves up and down, realizes accurate focus.
Fig. 3 shows the application framework of the driving glass slide automatic focusing of the accurate focusing device of digital slices scanning means
Figure.Scanning light source 301 is fixed on E shape fixed frame, enters optically focused through the mirror reflection light on 45 degree of optical adjusting frames 302
Mirror 303.Condenser gathers the light of entrance, across the unthreaded hole of lever quarter butt 211, through physics glass slice full of entire micro-
The 305 image space visual field of object lens.Imaging ray through microcobjective, 45 degree of the second reflective mirror 307 through being installed in E shape fixed plate
The light 308 of reflection enters scanning camera 311 through coaxial lens 309.Axis lens 309 are fixed on E shape by fixed frame 310 and fix
Frame 201.Accurate focusing mechanism drives physics glass slice to move up and down by thimble, it is ensured that cell is always in micro- object on slice
In the focus of mirror, accurate focusing is realized.
The work that Fig. 4 shows that the accurate focusing mechanism of the utility model embodiment drives glass slide to extreme position is illustrated
Figure.Voice coil motor 201 moves upwards, and one end that activation lever stock 208 connects rectangular elastic piece moves upwards.Strip elasticity
For piece due to the pulling force effect by lever stock, generating the elasticity mutually resisted with it being capable of restoring force F.It is connected to strip simultaneously
Effect of the lever quarter butt of spring leaf by spring-return power, generates upward movement.Thimble 212 on lever quarter butt drives object
Manage slicing motion.After lever motion to certain distance, the helicitic texture on lever stock will limit its movement, and slice stops at this time
Movement.
Embodiment described above is a kind of preferable scheme of the utility model, and so it is not practical to limit
It is novel.Those of ordinary skill in related technical field can be in the case where not departing from the spirit and scope of the utility model
It makes a variety of changes and modification.Therefore all mode technical solutions obtained for taking equivalent substitution or equivalent transformation, all fall within
In the protection scope of the utility model.
Claims (7)
1. being used for the accurate focusing mechanism of digital slices scanner, including displacement platform, thrust bindiny mechanism, lever mechanism, top
Needle and E shape fixed frame, it is characterised in that:
Displacement platform includes voice coil motor, crossed roller guide rail and mounting plate;Thrust bindiny mechanism is by being mounted on displacement platform
Thrust plate and a rectangular elastic piece form;Lever mechanism includes lever stock, lever quarter butt, lever supporting plate and strip elasticity
Piece;Thimble is a ball;E shape fixed frame is used for scanning constant light source, preview light source, micro- optical path and motion platform, specific:
Motor mount (201) fixed voice coil motor (207) is on E shape fixed frame 213, the motion parts of voice coil motor (207)
It is connect with thrust plate, and is provided with electromechanics position limiting structure between thrust plate, motor mount (201) and thrust plate (205)
The moving displacement of cooperation limitation voice coil motor (207);Crossed roller guide rail (204) is fixed on motor mount (201) and thrust
On plate (205), crossed roller guide rail (204) side is connect with motor fixing seat, and the other side is connect with thrust plate (205), voice coil
The movement of motor (207) will drive the movement of thrust plate, and crossed roller guide rail will guarantee the depth of parallelism and verticality of movement;Intersect
Grating sensor (203) and its corresponding reading head, real time monitoring feedback voice coil motor are installed on roller guide rail (204)
(207) moving displacement;The thrust plate is a L shape, and one end and voice coil motor move side and connect, the other end respectively with intersect
Roller movement side and the connection of rectangular elastic piece;Thrust plate is moved with voice coil motor (207), is crossed roller guide rail, grating sensing
Device and lever mechanism provide movement;Threaded hole on thrust plate (205) and motor mount (201) cooperates, and passes through screw, spring
Realize the limit moved to voice coil motor (207);Rectangular elastic piece (206) activation lever stock (208) movement, lever stock
(208) effect of the one end by the elastic-restoring force of strip elastic piece power, stop motion;Simultaneously lever quarter butt (211) due to
By the effect of elastic force, the movement opposite with lever stock one end direction of motion is generated;Drive the top on lever quarter butt (211)
Needle (212) movement, driving physics glass slice, which moves up and down, realizes accurate focus.
2. the accurate focusing mechanism according to claim 1 for digital slices scanner, it is characterised in that lever mechanism
Specifically include rectangular elastic piece (206), lever stock (208), lever supporting plate (219), strip elastic piece (210), rectangular small
Gasket, lever quarter butt (211), thimble (212);The lever stock (208) is connected by two through-holes of rectangular elastic piece (206)
It connects on the thrust plate with displacement platform;There are four through-holes above for the rectangular elastic piece (206);Two through hole is flat for connecting displacement
The thrust plate of platform, in addition two through hole is for connecting lever stock.
3. the accurate focusing mechanism according to claim 2 for digital slices scanner, it is characterised in that the lever
Stock (208) is a long T-shaped structure;There are the corresponding threaded holes of two tapped through holes Yu lever quarter butt (211) head in T forming head portion
It closes, realizes the connection of lever stock (208) and lever quarter butt (211);It is provided with a through-hole on lever stock (208), leads to
The threaded hole crossed in the through-hole and fixed plate cooperates, and realizes the limitation being displaced to lever motion.
4. the accurate focusing mechanism according to claim 3 for digital slices scanner, it is characterised in that the lever
Supporting plate (219) is a rectangular Al alloy block for being internally provided with central symmetry U-type groove;Its upper surface is provided with a threaded hole, is used for
Lever supporting plate (219) are fixed on a mounting board;Its side is provided with a threaded hole, for fixing strip elastic piece (210), and
The flank threads hole lower end is equipped with step, for positioning rectangular minipad;There are four through-holes on strip elastic piece (210), divide
Lever stock (208) and lever quarter butt (211) Wei not be connected, the work of fixed strip elastic piece is cooperated with lever supporting plate threaded hole
With.
5. the accurate focusing mechanism according to claim 4 for digital slices scanner, it is characterised in that the lever
Quarter butt (211) structure in T shape, the threaded hole on T shape both sides are used to connect lever stock by strip elastic piece (210)
(208);One end of the strip of lever quarter butt is provided with centrosymmetric unthreaded hole, for running through the light through glass slice,
Image in microcobjective;In strip one end of lever quarter butt, there is a hemispherical circular groove for fixing thimble (212).
6. the accurate focusing mechanism according to claim 5 for digital slices scanner, it is characterised in that described rectangular
Minipad is provided with central through hole, and matching thread is fixed strip elastic piece (210), and rectangular elastic piece uses spring steel, and
Spring leaf used with a thickness of 0.35mm, long 18mm, wide 22.5mm;The strip elastic piece uses spring steel plate, long
50mm, width 6mm, thickness 0.2mm;The long 175mm of lever stock, wide is respectively 18mm and 34mm, high 9mm;Using aluminium alloy material
Material, surface blackening processing;The fixed installation that the reading head mounting base is fixed on crossed roller guide rail is surveyed, grating scale peace
Mounted in the movement side of crossed roller guide rail;Grating scale is moved with respect to reading head, reads the move distance of displacement platform.
7. the accurate focusing mechanism according to claim 5 or 6 for digital slices scanner, it is characterised in that described
The ratio of lever quarter butt and lever stock is 1 to 7, and applies thrust, one end driving of lever quarter butt in one end of lever stock
Glass slice, the height ratio that glass slice movement and the movement of displacement platform can be obtained according to geometrical relationship is 1:7.
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CN109884060A (en) * | 2019-03-20 | 2019-06-14 | 武汉千屏影像技术有限责任公司 | A kind of accurate focusing mechanism for digital slices scanner |
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CN109884060A (en) * | 2019-03-20 | 2019-06-14 | 武汉千屏影像技术有限责任公司 | A kind of accurate focusing mechanism for digital slices scanner |
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