CN209646393U - A kind of non-concentric O shape channel microfluid mixer - Google Patents
A kind of non-concentric O shape channel microfluid mixer Download PDFInfo
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- CN209646393U CN209646393U CN201920071829.9U CN201920071829U CN209646393U CN 209646393 U CN209646393 U CN 209646393U CN 201920071829 U CN201920071829 U CN 201920071829U CN 209646393 U CN209646393 U CN 209646393U
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- microchannel
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Abstract
The utility model belongs to micro-fluidic chip field, specifically discloses a kind of non-concentric O shape channel microfluid mixer, including 2 entrances, 1 outlet, 6 microfluidic channels, 1 partition and 1 connection microchannel.By the microfluidic channel for designing special construction, in different zones of two kinds of microfluid streams through microchannel, it utilizes " the Coanda effect " of microfluidic flow, so that microfluid is dynamic along microchannel interior walls surface current, in two kinds of microfluid meets since chaotic advection forms Secondary Flow, Convention diffusion intensity is strengthened.The advantage of the utility model is: separating rate is fast, does not need design stop block structure, effectively prevents the inhibition of block during microfluidic flow；Other forms energy (such as magnetic, sound, electricity) input is not needed, only relying on microchannel structure change can be achieved with a variety of microfluids and effectively mix；Structure is simple, and processing cost is low.
Description
Technical field
The utility model relates to one kind to have new structural non-concentric O shape channel microfluid mixer, mixing side
Formula is passive type.
Background technique
Micro-fluidic chip is a kind of science and technology to be manipulated fluid for main feature in micro-meter scale space, tool
Have the ability on miniature to one several square centimeter chips of the basic function in the laboratories such as biology, chemistry, therefore is otherwise known as
Chip lab, important component of the microfluid mixer as micro-fluidic chip, it is sufficient to cause more to pay close attention to；With society
The continuous development and progress of meeting, before carrying out test reaction in the numerous areas such as chemical experiment, environmental monitoring and analysis, DNA detection
Microfluid mixer will be used, to realize being sufficiently mixed for plurality of reagents under different requirements.
Mixing typically refers to use mechanical or hydrokinetic method, two or more materials is made mutually to disperse and reach certain
The unit of uniformity coefficient operates, but has very big difference under the scale of micron dimension with macroscopic fluid flow, under micron dimension scale
The convection action of fluid is not strong, and in this case, the mixing of microfluid relies primarily on intermolecular diffusion, so
Under certain requirement of experiment, the mixing of microfluid becomes more difficult.The microfluid mixer of low cost passes through simple
Structure improvement is able to ascend the efficiency mixed between fluid, reaches expected mixed effect.
Microfluid mixer can be divided into passive microfluid mixer and active microfluid according to the difference of input energy
Two class of mixer；The former simple utilization geometry or fluid behaviour generate mixed effect, and the power flowed except driving fluid is (such as
Pressure, driven by electroosmosis etc.) outside, it mixes without the help of other external force, mixer is also free of any movable part；And the latter then borrows
The external force such as magnetic assist power, electric field force, sound field realize mixing.
The mixed effect of active mode mixer for microflow is preferable, but since structure is complicated, higher cost, in every field
The middle generality for realizing this technology is not high；Passive microfluid mixer structure is simple, fast response time, processing cost
It is low, it is easy to use, it is used widely in every field；The microfluid mixer of function admirable have quickly, efficiently, be easy to
The characteristics of controlling and being easily integrated, and cost is relatively low, and structure is simple, good mixing.
Summary of the invention
The utility model aim is that providing one kind has new structural non-concentric O shape channel microfluid mixer,
For advanced optimizing microchannel structure, reduce the resistance that microfluid flows in microchannel, during reducing microfluidic flow
It is lost along stroke pressure, removes unnecessary block, simplify overall construction design.
The technical solution of the utility model is: a kind of non-concentric O shape channel microfluid mixer, including first entrance,
It is second entrance, partition, the first microchannel, the second microchannel, third microchannel, the 4th microchannel, connection microchannel, the 5th micro- logical
Road, the 6th microchannel, outlet；The mixer it is characterized in that: the first microfluid from first entrance inject, second of microfluid from
Second entrance is injected, and is divided into two bursts of tributaries after two kinds of microfluids, upper tributary flows through the second microchannel, the 4th microchannel, lower branch
Stream flows through the first microchannel, third microchannel, and two bursts of tributaries are converged at connection microchannel entrance, and it is micro- logical to then flow through the 5th
Road, the 6th microchannel, the microfluid after outlet outflow mixing.
The non-concentric O shape channel microfluid mixer, it is characterized in that: the first microchannel, the second microchannel, third
Microchannel, the 4th microchannel form microring array sub-unit, and specific structure is microchannel and the 4th microchannel is by two rectangles
It constitutes, and the first microchannel and the 4th microchannel bilateral symmetry, 2 composition the of tangent circle 1 of two minimum points and circle
Two microchannels, third microchannel and the second microchannel are symmetrical above and below, the first microchannel and the 4th microchannel and the second microchannel and
Third microchannel overlapping.
The non-concentric O shape channel microfluid mixer, it is characterized in that: circle 1 and circle 2 half in microring array unit
The ratio between diameter 3:2, component is zero to distance of center circle in the horizontal direction, in the half that vertical direction component values are throat width；It is justified
1 center of circle of shape is overlapped with the long side length center of rectangle 1, and round 1 diameter is equal with the rectangle long numerical value of 1 long side, round 2 centers of circle and rectangle 2
Long side length center is overlapped, and round 2 diameters are equal with the rectangle long numerical value of 2 long side.
The non-concentric O shape channel microfluid mixer, it is characterized in that: first entrance and second entrance axis are flat
Row, two entrances are evenly spaced by partition, and partition is on two entrances boundary line, and partition central axes go out with microfluid mixer
Mouth axis collinear.
The non-concentric O shape channel microfluid mixer, it is characterized in that: the 5th microchannel is rectangle, the 6th is micro- logical
Road is the structure of 4 composition of circle 3 and circle of concentric circles；Microchannel is connected by left side microring array unit and the 5th microchannel of the right
Connection, specific structure is square structure, and width is consistent with microfluid mixer exit width.
The non-concentric O shape channel microfluid mixer, it is characterized in that: outlet is rectangle, width be first entrance,
The sum of width of second entrance.
The income of the utility model is: to guarantee under micron dimension scale, two kinds of microfluids can be realized well
Mixing needs to reinforce its convection action by the structure for changing microchannel.Compared to other forms microfluid mixer, this is practical
It is novel to use division microchannel structure, two kinds of microfluids are first divided into two bursts of tributaries, then two bursts of tributaries merge again, In
The tributary Liang Gu intersection, just forms Secondary Flow, effectively reinforces the convection action of microfluid.To guarantee that microfluid is flowing through microchannel
It is also able to achieve preferable mixing, second microchannel of the utility model and third microchannel in the process using change caliber bend pipe knot
Structure, since tube wall radius is different inside and outside this two segment pipe, the center of circle also not in same position, causes caliber different with position and becomes
Change, microfluid convection action during flowing through radius continually changing bend pipe is reinforced, and the mixing of microfluid is realized.Meanwhile
The utility model eliminates the block for hindering microfluidic flow, reduces energy loss and pressure of the microfluid in flow process
Loss is only just able to achieve by change microfluidic channel structure and is mixed well, and the structure design of microfluid mixer is simplified,
Processing cost is reduced, the integration of microfluid mixer is enhanced.
Detailed description of the invention
Fig. 1 is non-concentric O shape channel microfluid mixer two-dimensional structure schematic diagram, in figure: 1. first entrances, 2. second
Entrance, 3. partitions, 4. first microchannels, 5. second microchannels, 6. third microchannels, 7. the 4th microchannels, 8. connection microchannels,
9. the 5th microchannel, 10. the 6th microchannels, 11. outlets.
Fig. 2 is non-concentric O shape channel microfluid mixer geometry composition schematic diagram, entire microfluid mixer
Microchannel structure is formed by rectangle in figure with circular combination.
Fig. 3 is the geometry that non-concentric O shape channel microfluid mixer is mixed cell.
Fig. 4 is non-concentric O shape channel microfluid mixer concentration map, and white represents concentration as 1mol/m3, black representative
Concentration is 0mol/m3, color more shallowly represents that concentration is bigger, and exit concentration is in 0.5 mol/m3Left and right.
Specific embodiment
With reference to the accompanying drawing, the utility model is described in further detail.
A kind of non-concentric O shape channel microfluid mixer, including including 2 entrances, 1 is exported, 6 microfluids are logical
Road, 1 partition and 1 connection microchannel.
Specifically, the microfluid of the first concentration is injected from first entrance, and initial flow rate 0.1mm/s, second of concentration
Microfluid is injected from the second microfluidic inlet, initial flow rate 0.3mm/s, is flowed through each microchannel and is sufficiently mixed, from outlet
(11) it flows out；The density of two kinds of microfluids is 1000kg/m3, dynamic viscosity is for 0.001 Pas, and conductivity is
0.11845S/m, relative dielectric constant are 80.2.
Specifically, the initial concentration of the microfluid for the first concentration injected from first entrance is set as 1mol/m3, from second
The initial concentration of the microfluid of second of concentration of entrance injection is set as 0mol/m3, two kinds of microfluids flow through each microchannel it
In microfluid mixer outlet (11), outflow concentration theoretical value should be 0.5mol/m afterwards3。
Specifically, the micro-mixer throat width is 10 μm, exit width is 20 μm, and round 1 diameter is 60 μm, round
2 diameters are 40 μm, and round 3 diameters are 40 μm, and round 4 diameters are 20 μm, and the microfluid of two kinds of various concentrations injects two in parallel
Entrance.Rectangular Microchannel length is 20 μm, and width is 10 μm.
Specifically, the utility model concentration set by the dummy run phase is 1 mol/m3And 0mol/m3, grasped in specific experiment
It can be required according to actual experiment during work, be passed through the microfluid of specific concentration.
Claims (6)
1. a kind of non-concentric O shape channel microfluid mixer, including first entrance (1), second entrance (2), partition (3),
One microchannel (4), the second microchannel (5), third microchannel (6), the 4th microchannel (7), connection microchannel (8), the 5th micro- logical
Road (9), the 6th microchannel (10), outlet (11)；The mixer it is characterized in that: the first microfluid from first entrance (1) inject,
Second of microfluid is injected from second entrance (2), is divided into two bursts of tributaries after two kinds of microfluids, upper tributary flows through the second microchannel
(5), the 4th microchannel (7), lower tributary flow through the first microchannel (4), third microchannel (6), and two bursts of tributaries are in connection microchannel
(8) inlet is converged, and then flows through the 5th microchannel (9), the 6th microchannel (10), miniflow after being exported (11) outflow mixing
Body.
2. non-concentric O shape channel according to claim 1 microfluid mixer, it is characterized in that: the first microchannel (4),
Second microchannel (5), third microchannel (6), the 4th microchannel (7) form microring array sub-unit, and specific structure is first micro-
Channel (4) and the 4th microchannel (7) are to be made of two rectangles, and the first microchannel (4) and the 4th microchannel (7) control
Symmetrically, the tangent circle 1 of two minimum points and circle 2 constitute the second microchannel (5), third microchannel (6) and the second microchannel
(5) symmetrical above and below, the first microchannel (4) and the 4th microchannel (7) and the second microchannel (5) and third microchannel (6) overlap.
3. non-concentric O shape channel according to claim 1 microfluid mixer, it is characterized in that: circle in microring array unit
The ratio between shape 1 and round 2 radiuses 3:2, component is zero to distance of center circle in the horizontal direction, is throat width in vertical direction component values
Half；Its round 1 center of circle is overlapped with the long side length center of rectangle 1, and round 1 diameter is equal with the rectangle long numerical value of 1 long side, circle 2
The center of circle is overlapped with the long side length center of rectangle 2, and round 2 diameters are equal with the rectangle long numerical value of 2 long side.
4. non-concentric O shape channel according to claim 1 microfluid mixer, it is characterized in that: first entrance (1) and the
Two entrances (2) axis is parallel, and two entrances are evenly spaced by partition (3), and partition is on two entrances boundary line, and partition axis
Line is conllinear with microfluid mixer outlet axes.
5. non-concentric O shape channel according to claim 1 microfluid mixer, it is characterized in that: the 5th microchannel (9) is
Rectangle, the 6th microchannel (10) are the structures of 4 composition of circle 3 and circle of concentric circles；Microchannel (8) are connected by left side microring array
Unit is connect with the 5th microchannel (9) of the right, and specific structure is square structure, and width and microfluid mixer exit width
Unanimously.
6. non-concentric O shape channel according to claim 1 microfluid mixer, it is characterized in that: outlet (11) is rectangle,
Width is the sum of first entrance (1), the width of second entrance (2).
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| Application Number | Priority Date | Filing Date | Title |
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| CN201920071829.9U CN209646393U (en) | 2019-01-16 | 2019-01-16 | A kind of non-concentric O shape channel microfluid mixer |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111214991A (en) * | 2020-01-13 | 2020-06-02 | 清华大学 | Normal-temperature automatic mixing device for high-viscosity liquid |
| WO2021227544A1 (en) * | 2020-05-15 | 2021-11-18 | Stemirna Therapeutics Co., Ltd | Mixer for generating particles |
| CN113663573A (en) * | 2020-05-15 | 2021-11-19 | 斯微(上海)生物科技有限公司 | Mixer for particle generation |
| CN115318215A (en) * | 2022-08-19 | 2022-11-11 | 常州大学 | E-shaped micro-reactor channel structure |
-
2019
- 2019-01-16 CN CN201920071829.9U patent/CN209646393U/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111214991A (en) * | 2020-01-13 | 2020-06-02 | 清华大学 | Normal-temperature automatic mixing device for high-viscosity liquid |
| WO2021227544A1 (en) * | 2020-05-15 | 2021-11-18 | Stemirna Therapeutics Co., Ltd | Mixer for generating particles |
| CN113663573A (en) * | 2020-05-15 | 2021-11-19 | 斯微(上海)生物科技有限公司 | Mixer for particle generation |
| CN115318215A (en) * | 2022-08-19 | 2022-11-11 | 常州大学 | E-shaped micro-reactor channel structure |
| CN115318215B (en) * | 2022-08-19 | 2023-12-15 | 常州大学 | E-shaped microreactor channel structure |
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Granted publication date: 20191119 Termination date: 20220116 |