CN206381935U - A kind of asymmetric separation-and-combination structure passive type micro-mixers of 3D - Google Patents
A kind of asymmetric separation-and-combination structure passive type micro-mixers of 3D Download PDFInfo
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- CN206381935U CN206381935U CN201621399943.7U CN201621399943U CN206381935U CN 206381935 U CN206381935 U CN 206381935U CN 201621399943 U CN201621399943 U CN 201621399943U CN 206381935 U CN206381935 U CN 206381935U
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Abstract
The utility model is related to a kind of asymmetric separation-and-combination structure passive type micro-mixers of 3D, upper matrix and lower substrate are closely sealed, runner is etched with matrix, runner includes entrance channel, annular mixed cell, outlet flow, straight channel, each annular mixed cell is by a large circle runner, one small circle ring runner, a straight channel composition；Multiple annular mixed cells are series between straight channel, outlet flow；Straight channel and outlet flow axis collinear；Annular mixed cell is along the axial equidistant placement of axis；Fluid enters air stream enter runner from flow channel entry point, it can separate mixed flow because of interface abruptness when entering annular mixed cell, a part of fluid is transferred to annular channel and keeps laminar flow disperse state, it is a part of then flowed to vertical direction, can occur streamline disturbance because width narrows suddenly when being transferred to annular channel and produce Secondary Flow and into whirlpool, fluid separation, merge when, due to the convection current between fluid, collide, extrude so that sufficiently contacted between two fluids between two fluids.
Description
Technical field
The utility model is related to Microfluidic Mixing technical field in miniature hybrid chip and biochip, specifically one kind
The asymmetric separation-and-combination structure passive type micro-mixers of 3D.
Background technology
Micro-mixer, by its mixed performance rapidly and efficiently, extensively should as the important component of microfluidic system
For fields such as medicine preparation, chemical detection, cosmetics synthesis, due to its special size characteristic, in test or experiment both
Reagent can be saved, danger is reduced again（As strongly exothermic or toxic reagent reacts）.Fluid channel in microfluid micro-mixer
Size is between tens to hundreds of micrometer ranges, and the fluid in fluid channel is generally in laminar condition, and it, which is mixed, mainly passes through
Molecule spreads to realize, when being mixed for two strands or a plurality of fluids, is difficult to be sufficiently mixed between fluid, therefore realize that minute yardstick flows down
Body efficiently quickly mixes extremely important.
According to mixed process principle, micro-mixer is generally divided into reduction laminar-type and two kinds of laminar-type of reinforcing.Weaken laminar flow
It can be divided into two kinds of passive mixer and active mixer again according on mixing Producing reason in type.Active mixer is by additional
Disturbing source realizes mixing, and passive type then relies on the pressure source for forcing flow of fluid, and passive type micro-mixer internal structure changes
Flow of fluid trace can be caused to change, the change of fluid flow line adds the contact area between fluid molecule so that molecule
Diffusion accelerates, so as to reach the purpose for improving mixed effect.Compared to active micro-mixer, passive type structure is comparatively more
Simply, simplified manufacturing process, integration is higher, using more convenient.
Under microstate, mainly completed between each compounding substances by spreading, required time is typically longer, be unfavorable for carrying
The efficiency of height mixing.In order to improve the mixing efficiency of passive type micro-mixer, usually using circulation, layering, shearing, segmentation restructuring
Increase effective contact area between fluid etc. mode, circulation and segmentation recombinate the effective ways as lifting mixed effect, mainly
It is by changing the plan-position where runner, fluid split, converged so that each fluid layer blends each other, so as to increase
Plus the contact area between fluid, mixing diffusion length needed for shortening.
Utility model content
The purpose of this utility model is to provide a kind of asymmetric separation-and-combination structure passive type micro-mixers of 3D, its is simple in construction,
It is easy to process, it can be achieved rapidly and efficiently to mix between different fluid in microfluidic system.
To achieve the above object, the utility model provides following technical scheme：A kind of asymmetric separation-and-combination structures of 3D are passive
Decline blender, including upper substrate set up and down and infrabasal plate, and the infrabasal plate on upper substrate with being equipped with entrance channel
With outlet flow, the upper substrate is provided with the annular mixed cell connected with entrance channel, outlet flow with infrabasal plate, described
Mixed cell include the first arced flow path, the second arced flow path, the 3rd arced flow path, the 4th arced flow path, the first straight channel with
And second straight channel, first arced flow path, the second arced flow path and the first straight channel be arranged on infrabasal plate, and described
One arced flow path and the second arced flow path are interconnected by the first straight channel, the 3rd arced flow path, the 4th arced flow path
And second straight channel be arranged on upper substrate, the 3rd arced flow path and the 4th arced flow path are mutual by the second straight channel
Connection, first arced flow path is corresponding with the 3rd arced flow path to be set, second arced flow path and the 4th arced flow path
It is corresponding to set, first straight channel setting corresponding with the second straight channel, the entrance channel and the first arced flow path, the
Three arced flow paths are connected, and the outlet flow is connected with the second arced flow path, the 4th arced flow path.
Preferably, the width of first arced flow path is less than the width of the second arced flow path, the 3rd arc stream
The width in road is more than the width of the 4th arced flow path, and the size of first arced flow path is big with the runner of the 4th arced flow path
Small equal, the size of second arced flow path is equal in magnitude with the runner of the 3rd arced flow path.
Preferably, the center of circle of first arced flow path and the 4th arced flow path is in the first straight channel, the second straight channel
Axis on, first straight channel, the second straight channel and outlet flow axis collinear, and vertical with the axis of entrance channel.
Preferably, the entrance channel, the first straight channel, the second straight channel and outlet flow width are D, D's
Span is 100 μm≤D≤500 μm.
Preferably, the center of circle of first arced flow path and the second arced flow path center of circle are perpendicular to the first straight channel axis
It is upper conllinear, and the distance between two centers of circle are L3, the center of circle of the 3rd arced flow path and the 4th arced flow path center of circle perpendicular to
It is conllinear on first straight channel axis, and the distance between two centers of circle are L4, wherein L3=L4=D/2.
Preferably, the border of the 3rd arced flow path is L2 away from entrance channel frontier distance, entrance channel length is
L1, the length of the first straight channel and the second straight channel is L5, and outlet flow length is L6, wherein 1000 μm≤L1=L6≤2000 μ
M, L2=L5=1.5D.
Preferably, the radius length of second arced flow path and the 3rd arced flow path is R1, wherein R1=2D, it is described
The radius length of first arced flow path and the 4th arced flow path is R2, and wherein R2 is 1.5D.
Preferably, axis of the annular mixed cell along the first straight channel, the second straight channel is axial arranged, its middle ring
The number of shape mixed cell at least 3.
The beneficial effects of the utility model are：When fluid enters mixed cell by entrance channel by straight channel, meeting
Because cross section of fluid channel is mutated mixed flow is separated, a part keeps laminar condition to continue to keep laminar flow diffusion in upper matrix
By the 3rd annular channel and fourth annular runner, another part then produces a vertical direction flowing, then flows into lower substrate
First annular runner and the second annular channel in carry out acceleration flowing, formed a new tributary, in this switching flows side
During, Secondary Flow and vortex can be produced because of the transformation of streamline in the first straight channel and the second straight channel, make flow of fluid
State is disturbed, and then increases the contact area between fluid, increase mixed effect and mixing efficiency, is polymerize again in fluid separation
When, it due to the convection current between fluid, can to collide between two fluids, extrude so that sufficiently contacted between two fluids,
Increase contact area, promote mixed effect, and final one new horizontal interface of formation in next straight channel, then again
Into next mixed cell, fluid separation, polymerization are carried out, so constantly circulation, mixing efficiency is improved using the mutation in section.
On the one hand due to the presence in sidewalls vertical section, the segment fluid flow of runner side-walls is conducive to be sufficiently mixed, separately
On the one hand increase disturbance by the change of fluid channel geometry and the flow behavior of fluid, make fluid separation, polymerize
During increase the chaotic advection between fluid by Secondary Flow, into whirlpool, convection current etc., can further improve plane formula passively micro-
The mixed effect of blender, it is possible to achieve the quick mixing of minute yardstick.
Brief description of the drawings
Fig. 1 is a kind of asymmetric separation-and-combination structure passive type micro-mixer structure schematic diagrames of 3D of the invention；
Fig. 2 is 3D runner figures；
Fig. 3 is Fig. 2 A portions schematic diagram；
Fig. 4 is the structural representation of upper matrix.
Fig. 3 is the polarization curve in Active Drainage flow field and interdigitated flow field in the utility model embodiment.
In figure：1st, upper substrate；2nd, infrabasal plate；3rd, entrance channel；4th, outlet flow；5th, the first arced flow path；6th, the second arc
Shape runner；7th, the 3rd arced flow path；8th, the 4th arced flow path；9th, the first straight channel；10th, the second straight channel.
Embodiment
Referring to figs. 1 to shown in Fig. 4, the asymmetric separation-and-combination structure passive type micro-mixers of a kind of 3D that present case is implemented, including
Upper substrate 1 set up and down and infrabasal plate 2, the infrabasal plate 2 on upper substrate 1 with being equipped with entrance channel 3 and outlet flow
4, the upper substrate 1 is provided with the annular mixed cell connected with entrance channel 3, outlet flow 4, the mixing with infrabasal plate 2
Unit include the first arced flow path 5, the second arced flow path 6, the 3rd arced flow path 7, the 4th arced flow path 8, the first straight channel 9 with
And second straight channel 10, first arced flow path 5, the second arced flow path 6 and the first straight channel 9 be arranged on infrabasal plate 2,
The arced flow path 6 of first arced flow path 5 and second is interconnected by the first straight channel 9, the 3rd arced flow path 7, the
Four arced flow paths 8 and the second straight channel 10 are arranged on upper substrate 1, and the 3rd arced flow path 7 and the 4th arced flow path 8 lead to
Cross the second straight channel 10 to be interconnected, first arced flow path 5 and the corresponding setting of the 3rd arced flow path 7, second arc
Shape runner 6 and the corresponding setting of the 4th arced flow path 8, first straight channel 9 and the corresponding setting of the second straight channel 10, it is described
Entrance channel 3 is connected with the first arced flow path 5, the 3rd arced flow path 7, the arced flow path 6 of outlet flow 4 and second,
4th arced flow path 8 is connected.
The width of first arced flow path 5 is less than the width of the second arced flow path 6, the width of the 3rd arced flow path 7
Degree is more than the width of the 4th arced flow path 8, the size of first arced flow path 5 and the size of the runner of the 4th arced flow path 8
It is equal, the size of second arced flow path 6 and equal in magnitude, first arced flow path 5 of the runner of the 3rd arced flow path 7
The center of circle with the 4th arced flow path 8 is on the first straight channel 9, the axis of the second straight channel 10, first straight channel 9, second
Straight channel 10 and the axis collinear of outlet flow 4, and it is vertical with the axis of entrance channel 3.
The entrance channel 3, the first straight channel 9, the second straight channel 10 and the width of outlet flow 4 are D, D value
Scope is 100 μm≤D≤500 μm, and the center of circle and the center of circle of the second arced flow path 6 of first arced flow path 5 are straight perpendicular to first
It is conllinear on the axis of runner 9, and the distance between two centers of circle are L3, the center of circle and the 4th arced flow path 8 of the 3rd arced flow path 7
The center of circle is conllinear on the axis of the first straight channel 9, and the distance between two centers of circle are L4, wherein L3=L4=D/2, and described the
The border of three arced flow paths 7 is L2 away from the frontier distance of entrance channel 3, and the length of entrance channel 3 is L1, the first straight channel 9 and second
The length of straight channel 10 is L5, and the length of outlet flow 4 is L6, wherein 1000 μm≤L1=L6≤2000 μm, L2=L5=1.5D, institute
The radius length for stating the second arced flow path 6 and the 3rd arced flow path 7 is R1, wherein R1=2D, first arced flow path 5 and the
The radius length of four arced flow paths 8 is R2, and wherein R2 is 1.5D.
Axis of the annular mixed cell along the first straight channel 9, the second straight channel 10 is axial arranged, wherein annular mixing
The number of unit at least 3.
When fluid enters mixed cell by entrance channel 3 by straight channel, it can be mutated because of cross section of fluid channel and to mix
Stream is separated, and a part keeps laminar condition to continue to keep laminar flow to diffuse through the 3rd annular channel and the 4th in upper matrix
Annular channel, another part then produces a vertical direction flowing, then flows into the first annular runner and the second ring of lower substrate
Acceleration flowing is carried out in shape runner, a new tributary is formed, during this switching flows direction, in the first straight channel 9
With in the second straight channel 10 Secondary Flow and vortex can be produced because of the transformation of streamline, disturb fluid flow state, Jin Erzeng
Contact area between big fluid, increase mixed effect and mixing efficiency, when fluid separation polymerize again, due to pair between fluid
Stream, can to collide between two fluids, extrude so that sufficiently contacted between two fluids, increase contact area, promote
Mixed effect, and final one new horizontal interface of formation in next straight channel, are then again introduced into next mixing single
Member, carries out fluid separation, polymerization, so constantly circulation, and mixing efficiency is improved using the mutation in section.
Described above is only preferred embodiment of the present utility model, and protection domain of the present utility model is not limited merely to
Above-described embodiment, all technical schemes belonged under the utility model thinking belong to protection domain of the present utility model.It should refer to
Go out, for those skilled in the art, some improvement under the premise of the utility model principle is not departed from and
Retouching, these improvements and modifications also should be regarded as protection domain of the present utility model.
Claims (8)
1. a kind of asymmetric separation-and-combination structure passive type micro-mixers of 3D, it is characterised in that：Including upper substrate set up and down with
Infrabasal plate, the infrabasal plate on upper substrate with being equipped with entrance channel and outlet flow, and the upper substrate is provided with infrabasal plate
The annular mixed cell connected with entrance channel, outlet flow, the mixed cell includes the first arced flow path, the second arc stream
Road, the 3rd arced flow path, the 4th arced flow path, the first straight channel and the second straight channel, first arced flow path, the second arc
Shape runner and the first straight channel are arranged on infrabasal plate, and first arced flow path and the second arced flow path pass through the first direct current
Road is interconnected, and the 3rd arced flow path, the 4th arced flow path and the second straight channel are arranged on upper substrate, and the described 3rd
Arced flow path and the 4th arced flow path are interconnected by the second straight channel, first arced flow path and the 3rd arced flow path phase
It is correspondingly arranged, second arced flow path is corresponding with the 4th arced flow path to be set, first straight channel and the second straight channel
Corresponding to set, the entrance channel is connected with the first arced flow path, the 3rd arced flow path, the outlet flow and second
Arced flow path, the 4th arced flow path are connected.
2. the asymmetric separation-and-combination structure passive type micro-mixers of a kind of 3D according to claim 1, it is characterised in that：Described
The width of one arced flow path is less than the width of the second arced flow path, and the width of the 3rd arced flow path is more than the 4th arced flow path
Width, the size of first arced flow path and equal in magnitude, second arced flow path of the runner of the 4th arced flow path
Size and the runner of the 3rd arced flow path it is equal in magnitude.
3. the asymmetric separation-and-combination structure passive type micro-mixers of a kind of 3D according to claim 1 or 2, it is characterised in that：Institute
The center of circle of the first arced flow path and the 4th arced flow path is stated on the first straight channel, the axis of the second straight channel, described first is straight
Runner, the second straight channel and outlet flow axis collinear, and it is vertical with the axis of entrance channel.
4. the asymmetric separation-and-combination structure passive type micro-mixers of a kind of 3D according to claim 3, it is characterised in that：It is described enter
Mouthful runner, the first straight channel, the second straight channel and outlet flow width are D, and D span is the μ of 100 μm≤D≤500
m。
5. the asymmetric separation-and-combination structure passive type micro-mixers of a kind of 3D according to claim 4, it is characterised in that：Described
The center of circle of one arced flow path and the second arced flow path center of circle are conllinear on the first straight channel axis, and between two centers of circle away from
From for L3, the center of circle of the 3rd arced flow path and the 4th arced flow path center of circle are conllinear on the first straight channel axis, and
The distance between two centers of circle are L4, wherein L3=L4=D/2.
6. the asymmetric separation-and-combination structure passive type micro-mixers of a kind of 3D according to claim 5, it is characterised in that：Described
The border of three arced flow paths is L2 away from entrance channel frontier distance, and entrance channel length is L1, the first straight channel and the second direct current
The length in road is L5, and outlet flow length is L6, wherein 1000 μm≤L1=L6≤2000 μm, L2=L5=1.5D.
7. the asymmetric separation-and-combination structure passive type micro-mixers of a kind of 3D according to claim 6, it is characterised in that：Described
The radius length of two arced flow paths and the 3rd arced flow path is R1, wherein R1=2D, first arced flow path and the 4th arc stream
The radius length in road is R2, and wherein R2 is 1.5D.
8. the asymmetric separation-and-combination structure passive type micro-mixers of a kind of 3D according to claim 1 or 2 or 4 or 5 or 6 or 7, its
It is characterised by：Axis of the annular mixed cell along the first straight channel, the second straight channel is axial arranged, wherein annular mixing is single
The number at least 3 of member.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201621399943.7U CN206381935U (en) | 2016-12-20 | 2016-12-20 | A kind of asymmetric separation-and-combination structure passive type micro-mixers of 3D |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201621399943.7U CN206381935U (en) | 2016-12-20 | 2016-12-20 | A kind of asymmetric separation-and-combination structure passive type micro-mixers of 3D |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108201848A (en) * | 2016-12-20 | 2018-06-26 | 浙江工业大学 | A kind of 3D asymmetry separation-and-combination structure passive type micro-mixer |
| CN109248618A (en) * | 2018-09-17 | 2019-01-22 | 中国农业大学 | A kind of micro-mixer and detection system for greenhouse nutrient solutions detection |
| CN112161944A (en) * | 2020-10-14 | 2021-01-01 | 南京科创检测技术有限公司 | Ultraviolet-visible light measuring system and measuring method |
| WO2023186128A3 (en) * | 2022-04-02 | 2023-11-23 | 浙江吉量科技有限公司 | Mixing unit, mixer, micro-fluidic chip and mixing apparatus |
-
2016
- 2016-12-20 CN CN201621399943.7U patent/CN206381935U/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108201848A (en) * | 2016-12-20 | 2018-06-26 | 浙江工业大学 | A kind of 3D asymmetry separation-and-combination structure passive type micro-mixer |
| CN109248618A (en) * | 2018-09-17 | 2019-01-22 | 中国农业大学 | A kind of micro-mixer and detection system for greenhouse nutrient solutions detection |
| CN112161944A (en) * | 2020-10-14 | 2021-01-01 | 南京科创检测技术有限公司 | Ultraviolet-visible light measuring system and measuring method |
| WO2023186128A3 (en) * | 2022-04-02 | 2023-11-23 | 浙江吉量科技有限公司 | Mixing unit, mixer, micro-fluidic chip and mixing apparatus |
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| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20170808 Termination date: 20191220 |
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| CF01 | Termination of patent right due to non-payment of annual fee |