CN209081887U - Intestinal microorganism separation device - Google Patents
Intestinal microorganism separation device Download PDFInfo
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- CN209081887U CN209081887U CN201920077799.2U CN201920077799U CN209081887U CN 209081887 U CN209081887 U CN 209081887U CN 201920077799 U CN201920077799 U CN 201920077799U CN 209081887 U CN209081887 U CN 209081887U
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model provides an intestinal microorganism separating device, which comprises a feeding unit, a filtering unit and a split charging unit which are connected in sequence from top to bottom; the feeding unit comprises a raw material tank, and a stirring device is fixed at the bottom of the raw material tank; the split charging unit comprises a bacteria liquid storage tank; the separation device also comprises a vacuumizing device connected with a negative pressure interface of the bacteria liquid storage tank; the separation device also comprises a deodorization unit, and the deodorization unit is connected with the odor outlet of the original tank and the vacuumizing device. The feeding unit, the multistage filtering unit and the split charging unit in the separating device are vertically distributed, and the excrement raw material can flow to the next stage under the action of gravity and negative pressure by additionally arranging the vacuum pump, so that the blocking phenomenon in the filtering process is greatly reduced.
Description
Technical field
The utility model belongs to the field of medical instrument technology, is related to a kind of separator more particularly to a kind of microorganism
Separator, in particular to a kind of enteric microorganism separator.
Background technique
Flora in Normal Human Intestinal is to have been considered to be a special organ in human body, and caprophyl transplanting is considered as
A kind of special organ transplant.The bacterium of enteron aisle is about 1000 to 1050 kinds, at present function of the mankind to wherein Most bacterial
It organically works between energy and different bacterium according to what mechanism, it is all unclear.In recent years, modern medicine is more next
Enteric bacteria is more recognized in the intracorporal important function of people, will maintain or rebuild human body intestinal canal normal flora as a variety of
The critical treatment means of disease.Common probiotics drug and food are only by one or several kinds of bacteriums of enteron aisle, by external
Special culture, is then packed according to a certain amount.However, because be included in human body intestinal canal bacteria's numbers and species all
It is very limited, so its therapeutic value is also very limited.Last decade, caprophyl transplanting is gradually paid attention to, especially for normal
With the relevant disease of the invalid infection of antibiotic etc treatment, therapeutic value is particularly important, such as treatment antibiotic
Induced diarrhea, refractory inflammatory bowel disease, refractory type irritable bowel syndrome, immune-related intractable diarrhea, obesity, food
Allergy, depression bowel symptoms, fatty liver etc..
Caprophyl transplanting is a kind of method for treating disease by rebuilding intestinal flora, i.e., by the excrement of Healthy People at
It is obtained after reason beneficial to caprophyl liquid, i.e. the helminths such as removal worm's ovum only retain useful flora, capsulae enterosolubilis or indirect is then made
It is oral.The separation of intestinal flora at present has using artificial separation method, medical worker when preparing stool suspension, either from
Vision, smell are still psychological all beyond affordability；And partial automation equipment can not accomplish oxygen-free environment.Due to the bacterium in enteron aisle
Most group is anaerobic bacteria, and in separation process, fecal sample is exposed in oxygen for a long time, so that many anaerobic bacterias
It loses activity.
CN106367329A discloses microorganism and organic molecule rapidly and efficiently separator, including case in a kind of sample
Body and be set to the intracorporal agitator tank of case, filter, pressure pump, fluid collection device, deodorization device, water tank, agitator tank,
Filter, pressure pump, fluid collection device are sequentially connected；Be respectively equipped in the outer case the first air inlet, the second air inlet,
First gas outlet, the second gas outlet, second air inlet, the second gas outlet are connected to box house respectively；Described first into
The connection of the air inlet of port and agitator tank, the gas outlet of agitator tank, the gas outlet of filter, fluid collection device gas outlet point
It is not connect with deodorization device, the gas outlet of deodorization device is connect with the first gas outlet；Agitating device, mistake are equipped in the agitator tank
Filter screen is equipped in filter；The water tank is connect with the air inlet of the first air inlet and agitator tank respectively.The separator knot
Structure is simple, low in cost, easy to use, meets actual clinical needs.
CN108251288A discloses a kind of anaerobic type caprophyl extraction element and extracting method, and wherein extraction element includes sample
This acquisition device, collecting bag, crushing device and filter device；Sample collecting device includes the cylindrical collection container of upper end opening
With the upper cover that collection container upper surface is arranged in, circular through hole or ellipse hole, the lower section setting of upper cover are provided on upper lid
There is back taper collecting hood, collecting bag is arranged in collecting hood lower port；Collecting bag is provided with seal assembly on the side wall of opening, close
Sealing assembly can cover in the lower port of collecting hood；Dilution is held in collection container.The beneficial effects of the utility model are: this
Utility model is not only easy to operate, but also plastic sealing bag is combined to acquire fecal sample, as far as possible reduction fecal sample and air
Time of contact, improve caprophyl survival rate and therapeutic effect.
CN204311058U discloses microorganism separator in a kind of cavity content, wherein the discharge port of liquid storage bottle with
The entrance of classified filtering device is connected, and classified filtering device is made of one or more classified filtering bottles, liquid storage bottle liquid outlet
It is connected with liquid storage bottle filling opening and at least one classified filtering bottle, the material inlet and classified filtering of closed isolate tank
Device material outlet is connected, the bacterium solution entrance of the first sub-bottling for the subpackage apparatus being made of at least one sub-bottling with separate
The outlet of object tank bacterium solution is connected, and the foul smell entrance of deodorization device is exported respectively with liquid storage bottle foul smell by foul smell pipeline and isolate
The outlet of tank foul smell is connected, and is directed respectively into the foul smell in liquid storage bottle and isolate tank equipped at least one on foul smell pipeline and removes
The air pump of smelly device.The present apparatus realizes auto-filling, reduces bacterial content in impurity and improves bacterium collection rate and bacterium solution
Purity, its odorless generates, and treatment effeciency is high.
The separation of intestinal flora at present has using artificial separation method, medical worker when preparing stool suspension, no matter
It is from vision, smell or psychological all beyond affordability；And partial automation equipment can not accomplish oxygen-free environment.Therefore, it needs
Existing microorganism separator is improved, to solve the above technical problems.
Utility model content
In view of the deficienciess of the prior art, the purpose of this utility model is to provide a kind of separation of enteric microorganism to fill
It sets, the feed unit, multistage filtering, packing unit in the device are vertical distribution, and by adding vacuum pump, excrement raw material can be
It is flow to next stage under the action of gravity and negative pressure, greatly reduces the clogging in filter process.
For this purpose, the utility model uses following technical scheme:
The utility model provides a kind of enteric microorganism separator, and the separator includes from top to bottom sequentially connecting
Feed unit, filter element and the packing unit connect.
The feed unit includes original tank, and the original pot bottom is fixed with agitating device.
The packing unit includes bacterium solution holding vessel.
The separator further includes the vacuum evacuation device connecting with the negative port of the bacterium solution holding vessel.
The separator further includes deodorization unit, and the deodorization unit connects foul smell outlet and the institute of the original tank
State vacuum evacuation device.
Feed unit, filter element in enteric microorganism separator provided by the utility model is vertical with packing unit
It is distributed and has specific function division, excrement raw material can flow to next stage using the effect of gravity, negative pressure and positive pressure, subtract significantly
The clogging in filter process is lacked, and filter element simplifies the operating process of device, reduce without adding vibration device
The smell pollution and noise pollution that separation process generates.
With in a kind of sample disclosed in CN106367329A microorganism and organic molecule rapidly and efficiently separator phase
Than, the utility model by the way that agitating device is arranged in original pot bottom, when reducing manual setting-out, excrement raw material and oxygen are connect
It touching the time, excrement is about to excrement certainly and is put into original tank by the health worker of fecal sample to be collected, and transfer to medical worker to carry out,
Hereafter for medical worker without being again turned on original tank, on the one hand avoiding fecal sample and contacting with oxygen causes probiotics to be lost
It loses；On the other hand, decrease the peculiar smell of fecal sample generation it is to the working environment of medical worker and at heart healthy caused by not
Benefit influences.In addition be provided with vacuum evacuation device, shorten filtration time, also reduce excrement raw material may be contacted with oxygen it is general
Rate.
As the preferred technical solution of the utility model, the feed unit is included in the same horizontal position and is sequentially connected with
Liquid storage bottle and original tank.
As the preferred technical solution of the utility model, filling dilution inside the liquid storage bottle.
Preferably, the dilution includes ultrapure water or physiological saline, further preferred physiological saline.
Preferably, liquid outlet and the first evacuation port are provided at the top of the liquid storage bottle.
As the preferred technical solution of the utility model, the agitating device include stirring motor and with stirring electricity
The mixing blade of machine connection.
As the preferred technical solution of the utility model, the original tank includes tank body, and the tank base is provided with
For fixing the card slot pedestal of the stirring motor.
Preferably, the original tank top is provided with filling opening, the first inert gas entrance and foul smell outlet, the original
The filling opening of tank is connect with the liquid outlet of the liquid storage bottle.
Preferably, it is additionally provided on the filling opening of the original tank and the connecting line of the liquid outlet of the liquid storage bottle defeated
Send device.
Preferably, the conveying device is peristaltic pump.
Preferably, the original pot bottom is provided with material outlet.
Preferably, strainer is provided at the material outlet.
Preferably, the strainer is stainless steel filtering net.
As the preferred technical solution of the utility model, the filter element includes multistage filter.
Preferably, the multistage filter is arranged in below the original tank.
Preferably, it is provided with material inlet at the top of the multistage filter, the multistage filter bottom is provided with bacterium
Liquid outlet, the material inlet of the multistage filter connect the material outlet of the original tank.
Preferably, the multistage filter is internally provided at least one layer of strainer, is preferably provided with 3~6 layers of strainer, into
One step preferably 5 layers of strainer.
Preferably, the multistorey strainer mesh is nested in the inside cavity of the multistage filter with U-shaped pocket type.U-shaped pocket type
The problem of filter screen improves filter area, shortens filtration time, alleviates filter screen blocking to a certain extent appearance.
As the preferred technical solution of the utility model, the packing unit include sequentially connected bacterium solution holding vessel and
Sub-bottling group.
As the preferred technical solution of the utility model, the bacterium solution holding vessel is arranged under the multistage filter
Side.
Preferably, the sub-bottling group is arranged in below the bacterium solution holding vessel.
Preferably, refluxing opening, bacterium solution entrance, negative port and the second indifferent gas are provided at the top of the bacterium solution holding vessel
Body entrance, bacterium solution holding vessel lower part are provided with bacterium solution outlet, and the bacterium solution entrance of the bacterium solution holding vessel connects the multistage
The bacterium solution of filter exports, the negative port connection of the bacterium solution holding vessel vacuum evacuation device.
As the preferred technical solution of the utility model, the sub-bottling group includes at least one sub-bottling, preferably
At least two sub-bottling being sequentially connected in series, 4~12 sub-bottlings being further preferably sequentially connected in series.
Preferably, bacterium solution entrance and bacterium solution outlet are provided at the top of each sub-bottling, according to previous sub-bottling
Bacterium solution outlet connection the latter sub-bottling bacterium solution entrance connection type, each sub-bottling is sequentially connected in series.
Preferably, the bacterium solution entrance of first sub-bottling connects the bacterium solution outlet of the bacterium solution holding vessel.
Preferably, the bacterium solution outlet of the last one sub-bottling connects the refluxing opening of the bacterium solution holding vessel.
As the preferred technical solution of the utility model, the deodorization unit include sequentially connected deodorization surge flask and
Deodorization bottle, wherein be equipped with collection port and exhaust outlet at the top of the deodorization surge flask, the deodorization top of bottle be provided with deodorization mouth and
Second evacuation port.
The foul smell that the collection port of the deodorization surge flask is separately connected the original tank exports and the vacuum evacuation device,
The exhaust outlet of the deodorization surge flask connects the deodorization mouth of the deodorization bottle.
Preferably, it is also set up on the connecting line of the collection port of the foul smell outlet and deodorization surge flask of the original tank
There is conveying device, the conveying device is used to by original tank import foul smell in deodorization surge flask.
Using the microorganism in enteric microorganism separator separating feces provided by the utility model, concrete operation step
It is as follows:
(1) excrement raw material is put into original tank, and original tank is installed to the separator, the first inert gas entrance
It is passed through inert gas, the oxygen in separator is emptied；Dilution in liquid storage bottle imports original tank, opens agitating device,
Excrement raw material crush and be thoroughly mixed with dilution, the peculiar smell of generation is passed through in deodorization bottle；
(2) vacuum pump is opened, Multistage filtering device is evacuated to negative pressure, the excrement raw material after dilution passes through Multistage filtering device
Bacterium solution is obtained by filtration and collects into bacterium solution holding vessel, the peculiar smell of generation is passed through in deodorization bottle；
(3) it is passed through inert gas to the second inert gas entrance of bacterium solution holding vessel, bacterium solution is flowed by bacterium solution holding vessel divides
Bottling, completes packing, and the bacterium solution overflowed in sub-bottling is back to bacterium solution holding vessel.
Compared with prior art, the utility model has the following beneficial effects:
1, in order to create the oxygen-free environment for being conducive to microculture, on the one hand the utility model enters provided with inert gas
Mouthful, the oxygen in separator is emptied；On the other hand the installation site of agitating device, during the installation process, medical matters are improved
Personnel reduce a possibility that excrement raw material is contacted with oxygen, improve beneficial in gained bacterium solution without opening original top ends of cans
The type and relative abundance of bacterium, also improve the working environment of medical worker, alleviate stink to medical worker's physical and mental health
Adverse effect.
2, the feed unit in the device, filter element and packing unit vertical distribution, function division clear and definite；Pass through
Vacuum pump is additionally arranged at the bottom of in multistage filter, on the one hand, liquid passes through multistage filter under the action of can utilizing gravity and negative pressure,
Greatly reduce the clogging in filter process；On the other hand, the foul smell generated in bacterium solution holding vessel can be in the negative of vacuum pump
Pressure effect is pushed down into deodorization bottle, and stink is avoided to overflow, and pollutes working environment.
Detailed description of the invention
Fig. 1 is the schematic view of the front view for the enteric microorganism separator that a specific embodiment provides；
Fig. 2 is the side structure schematic view for the enteric microorganism separator that a specific embodiment provides；
Fig. 3 is the bacterium solution holding vessel regional area enlarged drawing in Fig. 2；
Fig. 4 is the overlooking structure diagram for the enteric microorganism separator that a specific embodiment provides；
Fig. 5 is the schematic diagram of internal structure for the original tank that a specific embodiment provides；
Fig. 6 is the multistage filter schematic diagram of internal structure that a specific embodiment provides；
Fig. 7 is the filter structure schematic diagram in Fig. 6；
Wherein: 1- original tank；101- filling opening；The first inert gas entrance of 102-；The outlet of 103- foul smell；104- stirring
Blade；105- material outlet；106- stainless steel filtering net；107- card slot pedestal；2- multistage filter；201- strainer；202- card
Slot；The feed(raw material)inlet 203-；The outlet of 204- bacterium solution；3- bacterium solution holding vessel；301- refluxing opening；302- bacterium solution entrance；303- negative pressure connects
Mouthful；The second inert gas entrance of 304-；The outlet of 305- bacterium solution；4- sub-bottling；5- liquid storage bottle；The first evacuation port of 501-；6- deodorization
Bottle；The second evacuation port of 601-；7- deodorization surge flask；8- air pump；9- first switch control valve；10- second switch control valve；11-
Third switching control pilot；12- stirring motor；13- vacuum pump；14- connection short tube；15- dispenses pipeline；16- return line；17-
First foul smell pipeline；18- the second foul smell pipeline；19- liquid feeding pipeline；20- peristaltic pump.
Specific embodiment
Further illustrate the technical solution of the utility model below with reference to the accompanying drawings and specific embodiments.
In a specific embodiment, the utility model provides a kind of micro- life of enteron aisle as shown in Figure 1, Figure 2 and Figure 4
Object separator, wherein Fig. 1 is the schematic view of the front view of the enteric microorganism separator, and Fig. 2 is the micro- life of the enteron aisle
The side structure schematic view of object separator, Fig. 4 is the overlooking structure diagram of the enteric microorganism separator, described
Enteric microorganism separator includes sequentially connected feed unit from top to bottom, filter element and packing unit.It is described into
Material unit includes original tank 1, and 1 bottom of original tank is fixed with agitating device；The packing unit includes bacterium solution holding vessel 3；
Described device further includes the vacuum pump 13 connecting with the bacterium solution holding vessel 3.
Feed unit is included in the sequentially connected liquid storage bottle 5 of the same horizontal position and original tank 1.Wherein, inside liquid storage bottle 5
Filling dilution, top are provided with liquid outlet and the first evacuation port 501 (as shown in Figure 1 and Figure 4).The internal junction of original tank 1
Structure is as shown in figure 5, include tank body, tank base is fixed with agitating device, and the agitating device includes 12 (such as Fig. 1 of stirring motor
With shown in Fig. 2) and the mixing blade 104 that is connect with the stirring motor, tank base be equipped with for fixing the stirring motor
12 card slot pedestal 107；Filling opening 101, the first inert gas entrance 102 and foul smell outlet 103 are provided at the top of original tank 1,
Wherein, the filling opening 101 of original tank 1 is connect with the liquid outlet of the liquid storage bottle 5；The filling opening 101 of the original tank 1 with
Peristaltic pump 20 is additionally provided on the connecting line of the liquid outlet of the liquid storage bottle 5；1 bottom of original tank is provided with raw material
105 are exported, is provided with stainless steel filtering net 106 at the material outlet 105.
Filter element includes the multistage filter 2 for being arranged in 1 lower section of original tank；The internal junction of the multistage filter
For structure as shown in fig. 6, top is provided with feed(raw material)inlet 203, bottom is provided with bacterium solution outlet 204, the feed(raw material)inlet of multistage filter 2
The material outlet 105 of 203 connection original tanks 1；Multistage filter 2 is internally provided at least one layer of strainer 201, the strainer 201
Structure as shown in fig. 7, the shell of strainer 201 and multistage filter 2 is fixed by card slot 202, be nested in U-shaped pocket type described in
The inside cavity of multistage filter 2.
Dispensing unit includes sequentially connected bacterium solution holding vessel 3 and sub-bottling group (as depicted in figs. 1 and 2)；Wherein, bacterium solution
Holding vessel 3 is arranged in 2 lower section of multistage filter, and sub-bottling group is arranged in 3 lower section of bacterium solution holding vessel.Bacterium solution holding vessel 3
Partial structurtes enlarged drawing as shown in figure 3, including being set to refluxing opening 301, bacterium solution entrance 302, negative port 303 at the top of it
With the second inert gas entrance 304, and be set to its underpart bacterium solution outlet 305.The bacterium solution entrance of the bacterium solution holding vessel 3
The bacterium solution outlet 204 of 302 connection multistage filters 2, the negative port 303 of bacterium solution holding vessel 3 connect vacuum pump 13.Sub-bottling
Group includes at least one sub-bottling 4, bacterium solution entrance and bacterium solution outlet is provided at the top of each sub-bottling 4, according to previous packing
The connection type of the bacterium solution entrance of bacterium solution outlet connection the latter sub-bottling of bottle, each sub-bottling is sequentially connected in series；The first point
The bacterium solution entrance of bottling connects the bacterium solution outlet 305 of the bacterium solution holding vessel 3, the bacterium solution outlet connection institute of the last one sub-bottling
State the refluxing opening 301 of bacterium solution holding vessel 3.
Described device further includes deodorization unit, and the deodorization unit connects foul smell outlet 103 and the institute of the original tank 1
State vacuum pump 13；The deodorization unit includes sequentially connected deodorization surge flask 7 and deodorization bottle 6.Wherein, deodorization surge flask 7
Top is equipped with collection port and exhaust outlet, is provided with deodorization mouth and the second evacuation port 601 at the top of the deodorization bottle 6；Deodorization surge flask 7
Collection port connect the foul smell the outlet 103 and vacuum pump 13 of the original tank 1, the exhaust outlet of the deodorization surge flask 7
Connect the deodorization mouth of the deodorization bottle 6.The connecting tube of the collection port of the foul smell outlet 103 and deodorization surge flask 7 of original tank 1
Road is additionally provided with air pump 8, and the air pump 8 is used to by original tank 1 import foul smell in deodorization surge flask 7.
The separator further includes necessary connecting line and switching control pilot between each device, and the utility model is to this
It is not particularly limited, those skilled in the art need to reasonably adjust according to needs of production, adds or delete, and need specific
It is to be substituted for Multifunctional centralized by deleting the inessential connecting line in part and switching control pilot, or by single function switching control pilot
At control valve or peripheral hardware with the automatic control system that switching control pilot is electrically connected for controlling the abilities such as corresponding valve opening
The new solution that field technique personnel are general and well known conventional technical means and generate equally falls into the disclosure of the utility model
Within range and protection scope.
The utility model provides a kind of optional technical solution, and described device further includes as shown in Figure 1, Figure 2 and Figure 4
Necessary connecting line and switching control pilot, specifically include:
(1) the liquid feeding pipeline 19 of the liquid outlet of liquid storage bottle 5 and the filling opening 101 of original tank 1 is connected；
(2) the feedstock transportation pipeline of the feed(raw material)inlet 203 of 1 bottom material outlet of original tank and multistage filter 2, institute are connected
It states feed line road and is provided with first switch control valve 9, flow into multistage filtering for controlling the excrement raw material in original tank 1
In device 2；
(3) the bacterium solution pipeline of connection 2 bacterium solution of multistage filter outlet 204 and 3 bacterium solution entrance 302 of bacterium solution holding vessel, it is described
It is provided with second switch control valve 10 on bacterium solution pipeline, flows into bacterium solution storage for controlling the bacterium solution that multistage filter 2 is obtained by filtration
It deposits in tank 3；
(4) the packing pipeline 15 of the bacterium solution entrance of connection 3 bacterium solution of bacterium solution holding vessel outlet 305 and first sub-bottling, institute
State and be provided with third switching control pilot 11 on packing pipeline 15, for control the bacterium solution collected in bacterium solution holding vessel 3 it is filling to point
In bottling 4；
(5) return line 16 for connecting the bacterium solution outlet and 3 refluxing opening 301 of bacterium solution holding vessel of the last one sub-bottling, is used
The bacterium solution overflowed in recycling sub-bottling 4；
(6) the connection short tube 14 for each sub-bottling of connecting；
(7) the first foul smell pipeline 17 of 7 foul smell entrance of deodorization surge flask and 1 foul smell of original tank outlet 103 is connected；Connection
Second foul smell pipeline 18 of 7 foul smell entrance of deodorization surge flask and vacuum pump, wherein the second foul smell pipeline is used for bacterium solution holding vessel 3
The foul smell of generation is exported by vacuum pump 13 into deodorization surge flask 7.
Above-mentioned connecting line and the switching control pilot opened or closed for control piper are only used as the utility model a kind of
Preferred connection relationship and installation site, material, model and tool of the utility model for control piper and switching control pilot
Body structure is not particularly limited, and the prior art that can be used to implement technical solutions of the utility model is used equally for the utility model
In, other variants and remodeling under the premise of without departing from technical solution documented by claim belong to the utility model
Protection scope.
Microorganism lock out operation, the lock out operation tool are carried out to fecal sample using above-mentioned enteric microorganism separator
Body includes the following steps:
(1) excrement raw material is put into original tank 1 and tightens by the health worker of sample to be collected, and the original of excrement raw material will be housed
Object tank 1 is installed to host；
(2) first switch control valve 9, second switch control valve 10 and the third switching control pilot in separator are opened
11, be passed through into original tank 1 inert gas by original tank 1 oxygen be discharged, close device in first switch control valve 9,
Second switch control valve 10 and third switching control pilot 11, and stop being passed through inert gas, it will be in liquid storage bottle 5 by peristaltic pump 20
Liquid dilution import original tank 1 in excrement raw material is diluted, open stirring；
(3) after the pulverized dilution of excrement, first switch control valve 9, second switch control valve 10 and vacuum pump are opened, simultaneously
Inert gas is passed through into original tank 1, the excrement raw material after crushing dilution is flowed by the stainless steel filtering net 106 of 1 bottom of original tank
The mixing blade 104 that 1 bottom of original tank is closed after to multistage filter 2, under the suction function that vacuum pump 13 generates, excrement is former
The bacterium solution containing intestine beneficial bacteria colony is obtained by filtration through multistage filter 2 in material, and bacterium solution is collected and stored by bacterium solution holding vessel 3, closes
Close inert gas, switching control pilot 2 and the vacuum pump 13 of 1 top of original tank；
(4) third switching control pilot 11 is opened, and is passed through inert gas into bacterium solution holding vessel 3, bacterium solution is stored by bacterium solution
Tank 3 is filling into sub-bottling 4, the last one sub-bottling is connected by return line 16 with bacterium solution holding vessel 3, overflows in sub-bottling 4
Bacterium solution is reflowable to bacterium solution holding vessel 3 out, after packing, closes inert gas, takes out sub-bottling 4, completes lock out operation.
Embodiment 1
Using the enteric microorganism separator that specific embodiment provides treat health worker's excrement of collecting sample into
Row microorganism lock out operation, the operating procedure include liquid feeding, stirring, filtering and packing, the specific process steps are as follows:
(1) liquid feeding: excrement is put into original tank 1 and tightens by the health worker of sample to be collected, and medical worker will be equipped with excrement
Just original tank 1 is installed to host；Open first switch control valve 9, second switch control valve 10 and third switching control pilot
11, it is passed through inert gas to first inert gas entrance 102 at 1 top of original tank, oxygen-free environment is manufactured in separator,
First switch control valve 9, second switch control valve 10 and the third switching control pilot 11 in separator are closed after 1min；It will storage
Physiological saline in liquid bottle 5 is imported in original tank 1 by liquid feeding pipeline 19 and peristaltic pump 20, liquid feeding 1min, liquid feeding volume and excrement
Just the total 800mL of raw material volume；Air pump 8 is opened, the excrement peculiar smell generated in original tank 1 by the first foul smell pipeline 17 and is removed
Smelly surge flask 7 is passed through in deodorization bottle 6, and the chemical reagent and adsorbent in deodorization bottle 6 decompose peculiar smell, adsorbed and eliminated；
(2) stir: opening agitating device, mixing blade 104 starts turning, to excrement raw material carry out broken stirring and with life
Reason salt water uniformly mixes, and total mixing time is 5min, and first switch control valve 9, second switch are opened when stirring is to 2min
Control valve 10 and vacuum pump 13, and it is passed through inert gas again to first inert gas entrance 102 at 1 top of original tank；
(3) filter: excrement raw material and physiological saline flow into multistage mistake by the material outlet 105 of original tank 1 after mixing
In filter 2, under the suction function that vacuum pump 13 generates, it is filtered operation, the bacterium solution being obtained by filtration is received by bacterium solution holding vessel 3
Collect and temporarily stores；The bacterium solution peculiar smell generated in bacterium solution holding vessel 3 by the second foul smell pipeline 18 and removes under the action of negative pressure
Smelly surge flask 7 is passed through into deodorization bottle 6, and the chemical reagent and adsorbent in deodorization bottle 6 decompose peculiar smell, adsorbed and disappeared
It removes；Vacuum pump 13 is closed after 5min and stops being passed through inert gas to the first inert gas entrance 102, and filter operation terminates；
(4) it dispenses: closing second switch control valve 10, open 3 top of third switching control pilot 11 and bacterium solution holding vessel
Second inert gas entrance 304, the inert gas of 2min is passed through to the second inert gas entrance 304, and bacterium solution passes through packing pipeline
15 flow into sub-bottling 4, after packing, take out sub-bottling 4, complete packaging operation, and the bacterium solution of spilling passes through return line 16
It is recycled in bacterium solution holding vessel 3.
It is sequenced using bis- generation of 16s and the relative abundance of beneficial bacterium and harmful bacteria after separating and filtering in gained bacterium solution is examined
It surveys, referring to table 1, (wherein, abundance " < 0.001% " indicates the content for detecting this kind of bacterium lower than 0.001% to test result；"-" table
Show and be not detected).
Record obtains time used in 600mL bacterium solution and in the same time the gained bacterium solution volume after separating and filtering,
Acquired results are shown in Table 2.
Comparative example 1
Comparative example 1 the difference from embodiment 1 is that, the agitating device in comparative example 1 is that stirring for original top ends of cans is arranged in
Stick is mixed, remaining device and connection relationship, operating condition and technological parameter and embodiment 1 are all the same.
It is sequenced using bis- generation of 16s and the relative abundance of beneficial bacterium and harmful bacteria after separating and filtering in gained bacterium solution is examined
It surveys, referring to table 1, (wherein, abundance " < 0.001% " indicates the content for detecting this kind of bacterium lower than 0.001% to test result；"-" table
Show and be not detected).
Comparative example 2
Comparative example 2 the difference from embodiment 1 is that, the not set vacuum pump of comparative example 2, remaining device and connection relationship, behaviour
Make condition and technological parameter and embodiment 1 is all the same.
Record obtains time used in 600mL bacterium solution and in the same time the gained bacterium solution volume after separating and filtering,
Acquired results are shown in Table 2.
Table 1
Table 2
Comprehensive analysis is carried out to embodiment 1, comparative example 1 and comparative example 2:
(1) installation site that agitating device is changed in comparative example 1, moves to original top ends of cans for agitating device, can from table 1
To find out, the type of beneficial bacterium is significantly more than in comparative example 1 in 1 gained bacterium solution of embodiment, and the relative abundance of beneficial bacterium
It is higher than in comparative example 1, this is because changing the position of agitating device, bring is medical worker in the installation original therewith
Operation change during tank, since agitating device is on top, medical worker needs to open during the installation process top cover and excrement is added
Just raw material, the excrement raw material that do not can guarantee in original tank in the process is in the environment of complete anaerobic, and the bacterium in enteron aisle
Most group is anaerobic bacteria, and in separation process, excrement raw material is exposed in oxygen, so that many anaerobic bacterias lose work
Property, cause profitable strain to lack.And agitating device is fixed on original pot bottom, the Healthy People of sample to be collected by the utility model
Excrement directly can be fitted into original tank and be sealed by member, then medical worker is transferred to carry out later separation operation, on the one hand, excrement
Just enter after original tank and no longer directly contacted with air generation, avoid excrement and contacted with oxygen；On the other hand, medical worker without
Excrement need to be put into original tank, reduce excrement peculiar smell and have an adverse effect to the physical and mental health of medical worker.
(2) vacuum pump is eliminated in comparative example 2, as can be seen from Table 2, before obtaining 600mL volume bacterium solution
It puts, the time used in comparative example 2 is significantly larger than in embodiment 1；Similarly, in the same time, comparative example 2 is obtained by filtration
Bacterium solution volume also well below in embodiment 1.This is because, can not divide after eliminating vacuum pump in filter operation
From generating negative pressure in device, so as to cause rate of filtration reduction, excrement raw material easily block strainer to influence filtration time with
Finally obtained bacterium solution amount.On the other hand, vacuum pump is in separator provided by the utility model in addition to accelerating filtering rate
Except, it also acts the effect of the foul smell indentation deodorization bottle in bacterium solution holding vessel.
The Applicant declares that the foregoing is merely specific embodiment of the present utility model, but the protection model of the utility model
It encloses and is not limited thereto, it should be clear to those skilled in the art, any to belong to those skilled in the art and exist
In the technical scope that the utility model discloses, any changes or substitutions that can be easily thought of, all falls within the protection scope of the utility model
Within the open scope.
Claims (33)
1. a kind of enteric microorganism separator, which is characterized in that the separator include from top to bottom it is sequentially connected into
Material unit, filter element and packing unit；
The feed unit includes original tank, and the original pot bottom is fixed with agitating device；
The packing unit includes bacterium solution holding vessel；
The separator further includes the vacuum evacuation device connecting with the negative port of the bacterium solution holding vessel；
The separator further includes deodorization unit, and the deodorization unit connects the foul smell outlet and the pumping of the original tank
Vacuum plant.
2. the apparatus according to claim 1, which is characterized in that the feed unit is included in the same horizontal position sequentially
The liquid storage bottle and original tank of connection.
3. the apparatus of claim 2, which is characterized in that filling dilution inside the liquid storage bottle.
4. device according to claim 3, which is characterized in that the dilution includes ultrapure water or physiological saline.
5. device according to claim 4, which is characterized in that the dilution is physiological saline.
6. the apparatus of claim 2, which is characterized in that be provided with liquid outlet and first at the top of the liquid storage bottle
Evacuation port.
7. the apparatus according to claim 1, which is characterized in that the agitating device includes stirring motor and stirs with described
Mix the mixing blade of motor connection.
8. the apparatus according to claim 1, which is characterized in that the original tank includes tank body, and the tank base is set
It is equipped with the card slot pedestal for fixing the stirring motor.
9. the apparatus according to claim 1, which is characterized in that the original tank top is provided with filling opening, the first inertia
Gas access and foul smell outlet, the filling opening of the original tank are connect with the liquid outlet of the liquid storage bottle.
10. device according to claim 9, which is characterized in that the filling opening of the original tank and the liquid of the liquid storage bottle
Conveying device is additionally provided on the connecting line of body outlet.
11. device according to claim 10, which is characterized in that the conveying device is peristaltic pump.
12. the apparatus according to claim 1, which is characterized in that the original pot bottom is provided with material outlet.
13. device according to claim 12, which is characterized in that be provided with strainer at the material outlet.
14. device according to claim 13, which is characterized in that the strainer is stainless steel filtering net.
15. the apparatus according to claim 1, which is characterized in that the filter element includes multistage filter.
16. device according to claim 15, which is characterized in that the multistage filter is arranged under the original tank
Side.
17. device according to claim 15, which is characterized in that be provided with material at the top of the multistage filter and enter
Mouthful, the multistage filter bottom is provided with bacterium solution outlet, and the material inlet of the multistage filter connects the original tank
Material outlet.
18. device according to claim 15, which is characterized in that the multistage filter is internally provided at least one layer
Strainer.
19. device according to claim 18, which is characterized in that the multistage filter is internally provided with 3~6 layers of filter
Net.
20. device according to claim 19, which is characterized in that the multistage filter is internally provided with 5 layers of strainer.
21. device according to claim 13, which is characterized in that the multistorey strainer mesh is nested in described with U-shaped pocket type
The inside cavity of multistage filter.
22. the apparatus according to claim 1, which is characterized in that the packing unit includes sequentially connected bacterium solution storage
Deposit tank and sub-bottling group.
23. device according to claim 22, which is characterized in that the bacterium solution holding vessel is arranged in the multistage filtering
Below device.
24. device according to claim 22, which is characterized in that the sub-bottling group is arranged in the bacterium solution holding vessel
Lower section.
25. device according to claim 22, which is characterized in that be provided at the top of the described bacterium solution holding vessel refluxing opening,
Bacterium solution entrance, negative port and the second inert gas entrance, bacterium solution holding vessel lower part are provided with bacterium solution outlet, the bacterium solution
The bacterium solution that the bacterium solution entrance of holding vessel connects the multistage filter exports, described in the negative port connection of the bacterium solution holding vessel
Vacuum evacuation device.
26. device according to claim 22, which is characterized in that the sub-bottling group includes at least one sub-bottling.
27. device according to claim 26, which is characterized in that the sub-bottling group includes at least 2 be sequentially connected in series
A sub-bottling.
28. device according to claim 27, which is characterized in that the sub-bottling group includes 4~12 be sequentially connected in series
A sub-bottling.
29. device according to claim 26, which is characterized in that be provided with bacterium solution entrance at the top of each sub-bottling
It is exported with bacterium solution, it, will according to the connection type of the bacterium solution entrance of bacterium solution outlet connection the latter sub-bottling of previous sub-bottling
Each sub-bottling is sequentially connected in series.
30. device according to claim 29, which is characterized in that described in the bacterium solution entrance connection of first sub-bottling
The bacterium solution of bacterium solution holding vessel exports.
31. device according to claim 29, which is characterized in that the bacterium solution outlet connection institute of the last one sub-bottling
State the refluxing opening of bacterium solution holding vessel.
32. the apparatus according to claim 1, which is characterized in that the deodorization unit includes that sequentially connected deodorization is slow
Rush bottle and deodorization bottle, wherein collection port and exhaust outlet are equipped at the top of the deodorization surge flask, the deodorization top of bottle, which is provided with, to be removed
Smelly mouth and the second evacuation port.
The foul smell that the collection port of the deodorization surge flask is separately connected the original tank exports and the vacuum evacuation device, described
The exhaust outlet of deodorization surge flask connects the deodorization mouth of the deodorization bottle.
33. device according to claim 32, which is characterized in that the foul smell outlet and deodorization buffering of the original tank
Conveying device is additionally provided on the connecting line of the collection port of bottle, the conveying device is used to foul smell importing deodorization by original tank
In surge flask.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920077799.2U CN209081887U (en) | 2019-01-17 | 2019-01-17 | Intestinal microorganism separation device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920077799.2U CN209081887U (en) | 2019-01-17 | 2019-01-17 | Intestinal microorganism separation device |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109517727A (en) * | 2019-01-17 | 2019-03-26 | 上海宝藤生物医药科技股份有限公司 | Separation device and separation method for intestinal microorganisms |
| CN112742100A (en) * | 2020-12-03 | 2021-05-04 | 淮阴师范学院 | Intestinal flora extraction element |
-
2019
- 2019-01-17 CN CN201920077799.2U patent/CN209081887U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109517727A (en) * | 2019-01-17 | 2019-03-26 | 上海宝藤生物医药科技股份有限公司 | Separation device and separation method for intestinal microorganisms |
| CN112742100A (en) * | 2020-12-03 | 2021-05-04 | 淮阴师范学院 | Intestinal flora extraction element |
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