CN206173343U - Microorganism and organic molecule high efficiency separator in sample - Google Patents
Microorganism and organic molecule high efficiency separator in sample Download PDFInfo
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- CN206173343U CN206173343U CN201621100677.3U CN201621100677U CN206173343U CN 206173343 U CN206173343 U CN 206173343U CN 201621100677 U CN201621100677 U CN 201621100677U CN 206173343 U CN206173343 U CN 206173343U
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Abstract
The utility model provides a pair of microorganism and organic molecule high efficiency separator in sample, agitator tank, filter, force pump, liquid collecting device, deodorizing device, water storage tank in including the box and locating the box, agitator tank, filter, force pump, liquid collecting device connect gradually, be equipped with first air inlet, second air inlet, first gas outlet, second gas outlet on the box respectively, second air inlet, second gas outlet communicate with the box is inside respectively, first air inlet is connected with the air inlet of agitator tank, and the gas outlet of agitator tank, the gas outlet of filter, liquid collecting device's gas outlet is connected with deodorizing device respectively, and deodorizing device's gas outlet and first gas outlet are connected, be equipped with agitating unit in the agitator tank, be equipped with the filter screen in the filter, the water storage tank is connected with the air inlet of first air inlet and agitator tank respectively. This separator simple structure, low cost, convenient to use satisfy actual clinical needs.
Description
Technical field
This utility model belongs to technical field of medical instruments, micro- in more particularly to a kind of quick automatic separation biased sample
The device of grain thing, specifically containing the microorganism in object sample and organic molecule rapidly and efficiently segregation apparatuss.
Background technology
The micro organism quantity contained in human body exceedes more than 10 times of human body own cells, wherein intestinal microflora most
For huge, it all plays extremely important work to aspects such as nutrient metabolism, human body itself development, immunity and generations of disease
With.Many results of study all show that the composition of enteric microorganism is closely related with various disease incidences, such as intestinal tract disease, obesity,
The diseases such as cholelithiasis, diabetes, cancer, hypertension, hyperlipidemia, or even the mental status of infantile autism, depression and people are all therewith
There is directly contact.In clinical practice, progressively using intestinal microbial population regulation as an important target for treating various diseases
Point, the most direct mode of one of which is exactly that the human body intestinal canal flora of health is transplanted to after treatment in Intestinal Mucosal Injury in Patients Undergoing,
But it is that a time, environmental condition require harsh process, effective acquisition intestinal to obtain the processing procedure of healthy human body intestinal microbial population
These target components in road, need to rely on professional equipment to complete.
" caprophyl transplanting " is also referred to as " feces transplanting ", " caprophyl treatment ", " Enterobacter cloaca transplanting " or " transplanting of intestinal Tiny ecosystem ", excrement
Bacterium transplanting is also considered as a kind of transplanting of special organ, diseases related in the invalid infection for the treatment of antibiotic etc, such as
Antibiotic-associated diarrhea, Treatment of Refractory Irritable Bowel Syndrome, immune-related intractable diarrhoea, refractory inflammatory bowel disease, difficulty
Clostridial infection, food anaphylaxiss, obesity, depression bowel symptoms, fatty liver etc. are distinguished, therapeutic effect is especially pronounced, so far
About 10,000 patients receive caprophyl transplantation treatment in the modern whole world.Human body intestinal canal endoparasitism about 1,000,000,000,000,000 antibacterials, about
500~1000 different species, because the intestinal environment oxygen content that it is survived is low, temperature is body temperature 35 DEG C to 40
DEG C, therefore most of intestinal bacteria is anaerobic bacteria.Have at present 50%-90% intestinal bacteria can not by artificial culture out,
It is limited to the understanding of its function and conditions of existence.In caprophyl transplantation treatment, one of object of transplanting is exactly viable bacteria, it is ensured that living
Bacterium implantation rate is the successful basic guarantee for the treatment of.The main source for obtaining caprophyl is the feces of healthy human body, is contaminated with feces
The solid particles such as food debriss, crude fibre, it is necessary first to carry out filtration treatment.Intestinal microbial population is being obtained from healthy human body feces
In operating process：1. how to ensure pollution-free；2. anaerobe is avoided to contact oxygen loss；3. how control operation ambient temperature makes
Obtain thalline loss rate minimum, overall structure keeps constant；4. how object is quickly obtained, is all the problems such as meet clinical needs
Obtain the key technical problems of caprophyl.
Probioticss in intestinal, such as bacillus bifiduss, lactobacilluss etc. can synthesize the necessary dimension life of various growth in humans's developments
Element, such as vitamin B group (vitamin B1, B2, B6, B12), vitamin K, nicotinic acid, pantothenic acid etc., moreover it is possible to closed using protein residue
Into essential amino acids.Intestinal microbial population not being host marking, but with human body symbiotic population, metabolism source of the intestinal microbial population in intestinal
Source is constantly to provide human body necessary nutrient substance, therefore gut metabolism also becomes " first metabolism ".Metabolite is to act on
Each tissue of human body and the most direct material of organ, therefore another object transplanted in caprophyl migration process is needed by human body
Bacterial metabolism product.General organic metabolite stability is poor, unstable under the conditions of high temperature aerobic environment for a long time, is obtaining
To take remained a need for during donor gut metabolism product and solve the problems, such as sample treatment temperature, oxygen concentration and time.
Utility model content
Technical problem：In order to solve the defect of prior art, this utility model provide the microorganism in a kind of sample and
Organic molecule rapidly and efficiently segregation apparatuss.
Technical scheme：Microorganism and organic molecule in a kind of sample that this utility model is provided rapidly and efficiently separates dress
Put, including casing and the agitator tank in casing, filter, compression pump, fluid collection device, odor removal, water storage
Tank, agitator tank, filter, compression pump, fluid collection device are sequentially connected；Be respectively equipped with the casing the first air inlet,
Two air inlets, the first gas outlet, the second gas outlet, second air inlet, the second gas outlet connect respectively with box house；Institute
State the first air inlet to be connected with the air inlet of agitator tank, the gas outlet of agitator tank, the gas outlet of filter, fluid collection device
Gas outlet is connected respectively with odor removal, and the gas outlet of odor removal is connected with the first gas outlet；It is provided with the agitator tank and stirs
Device is mixed, drainage screen is provided with filter；The water tank is connected respectively with the air inlet of the first air inlet and agitator tank.
Used as improvement, also including sterilizing lamp, the sterilizing lamp is in casing.
Used as another kind of improvement, also including temperature control equipment, the temperature control equipment is in casing.
As another kind of improvement, also including first gas defecator and second gas defecator, the first gas
Defecator is connected respectively with the first air inlet, the second air inlet, the second gas defecator respectively with the first gas outlet,
Second gas outlet connects.First gas defecator is passed through pure gases or two or more mixed gas；Preferably, the first gas
The gas that body defecator is passed through is other gases beyond oxygen, can create oxygen-free environment.
As another kind of improvement, also including gas-detecting device, the gas-detecting device respectively with the first gas outlet, the
Two gas outlets connect.
Used as another kind of improvement, the filter is provided with the device for making material concussion to be filtered in filter；Preferably,
The filter is provided with the agitator for making filter body vibration, or the vibration dress for vibrating drainage screen is provided with filter
Put.
As another kind of improvement, multiple filtration net is provided with the filter；Drainage screen be arranged in parallel from top to bottom
One group of filter screen, its aperture is sequentially reduced from top to bottom；Or drainage screen is to be obliquely installed one group of filter screen, adjacent screen from top to bottom
Edge is abutted against or is not abutted against, and its aperture is sequentially reduced from top to bottom；Filter screen is flat screen, or middle part is to lower recess, or
Middle part raises up.
Used as another kind of improvement, the fluid collection device includes one group of receiving flask being arranged in series, seals receiving flask
The syringe needle for receiving flask series connection in rubber stopper, the sterilization plug of parcel rubber stopper, insertion plug, syringe needle is big transfusion plug bottle
Pin；Cotton ball soaked in alcohol is provided with sterilization plug.
Used as another kind of improvement, the odor removal includes air inlet pipe and escape pipe；The gas outlet of air inlet pipe is located at and removes
Smelly device bottom, the gas feed of escape pipe is located at odor removal top.
This utility model additionally provides a kind of utilization said apparatus to the microorganism in sample and organic molecule rapidly and efficiently
Detached method, comprises the following steps：
(1) it is other gases beyond oxygen that first gas defecator is passed through gas, and the second air inlet is by casing
Air is discharged, and the first air inlet discharges the air in agitator tank, filter, fluid collection device, odor removal, makes in device
Form oxygen-free environment；
(2) sample to be separated is placed in agitator tank, suitable quantity of water is pressed in agitator tank using water tank, open stirring
Device is stirred；
(3) slurry in agitator tank enters sucking filtration in filter, and the filtrate containing microorganism and organic molecule is received by liquid
Acquisition means are collected；
(4) first air inlets are passed through gas in agitator tank, and bring deodorization in odor removal into；Meanwhile, filter and
Gas in fluid collection device is passed through deodorization in odor removal.
Beneficial effect：The segregation apparatuss simple structure, with low cost, easy to use that this utility model is provided, it is ensured that point
Close pollution-free from integrated operation environment, while anaerobic environment or aerobic environment can be manufactured, sample temperature in control separation process
With the final temperature for obtaining bacterium solution, object is efficiently quickly obtained within the shortest time, to meet actual clinical needs.
Description of the drawings
Fig. 1 is the structural representation of the microorganism in this utility model sample and organic molecule rapidly and efficiently segregation apparatuss.
Fig. 2 is the structural representation that adjacent screen edge is abutted against in filter.
Fig. 3 is structural representation of the middle part to the filter screen of lower recess in filter.
Fig. 4 is the structural representation of the filter screen that middle part raises up in filter.
Fig. 5 is the structural representation of fluid collection device.
Specific embodiment
This utility model is further illustrated below.
Microorganism and organic molecule in sample rapidly and efficiently segregation apparatuss, are shown in Fig. 1, including casing 1 and located at casing
Agitator tank 2, filter 3 in 1, compression pump 4, fluid collection device 5, odor removal 6, water tank 7, sterilizing lamp 8, temperature control
Device 9, first gas defecator 15 and second gas defecator 16, gas-detecting device 17, agitator tank 2, filter 3,
Compression pump 4, fluid collection device 5 are sequentially connected；The first air inlet 11, the second air inlet 12 are respectively equipped with casing 1, first are gone out
QI KOU 13, the second gas outlet 14；First gas defecator 15 is connected respectively with the first air inlet 11, the second air inlet 12, the
Two gas-filtering devices 16 are connected respectively with the first gas outlet 13, the second gas outlet 14, gas-detecting device 17 and second gas
Defecator 16 connects, and the second air inlet 12, the second gas outlet 14 connect respectively with the inside of casing 1；First air inlet 11 with stir
Mix the air inlet connection of tank 2, the gas outlet of agitator tank 2, the gas outlet of filter 3, fluid collection device 5 gas outlet respectively with
Odor removal 6 connects, and the gas outlet of odor removal 6 is connected with the first gas outlet 13；Agitating device 21, mistake are provided with agitator tank 2
Drainage screen 31 is provided with filter 3；Water tank 7 is connected respectively with the air inlet of the first air inlet 11 and agitator tank 2；Sterilizing lamp 8 sets
In casing 1；Temperature control equipment 9 is in casing 1.
Filter 3 is provided with the device for making material concussion to be filtered in filter 3；Filter 3 is provided with makes filter 3 whole
The agitator 32 of body vibration, or the vibrating device for vibrating drainage screen 31 is provided with filter 3, can realize that this practicality is new
Type purpose.
Multiple filtration net 31 is provided with filter 3；The setting of drainage screen can take various forms, and can realize this practicality
New purpose, for example：Drainage screen 31 is one group of filter screen be arrangeding in parallel from top to bottom, and its aperture is sequentially reduced from top to bottom,
See Fig. 1；Or drainage screen 31, to be obliquely installed one group of filter screen from top to bottom, adjacent screen edge is abutted against to be seen Fig. 2 or is not abutted against, its
Aperture is sequentially reduced from top to bottom；Filter screen 31 is flat screen, or middle part sees Fig. 3 to lower recess, or middle part raises up
See Fig. 4.
Odor removal 6 includes air inlet pipe 61 and escape pipe 62；The gas outlet of air inlet pipe 61 is located at the bottom of odor removal 6,
The gas feed of escape pipe 62 is located at the top of odor removal 6.
Fluid collection device 5, is shown in Fig. 5, including one group of receiving flask 51 being arranged in series, rubber stopper of sealing receiving flask 51
52nd, the sterilization plug 54 for wrapping up rubber stopper 52, the syringe needle 53 for the series connection of receiving flask 51 inserted in plug 52, syringe needle 53 is big defeated
Liquid needle for inserting bottle；Cotton ball soaked in alcohol is provided with sterilization plug 54；There is many benefits using big needle for inserting bottle for infusion：First, side
Just receiving flask is changed；Second, wide material sources are aseptic.
Using said apparatus to the microorganism in sample and organic molecule rapidly and efficiently detached method, step is as follows：
(1) first gas defecator 15 is passed through gas for other gases beyond oxygen, and the second air inlet 12 is by casing 1
Interior air is discharged, and the first air inlet 11 arranges the air in agitator tank 2, filter 3, fluid collection device 5, odor removal 6
Go out, make to form oxygen-free environment in device；
(2) sample to be separated is placed in agitator tank 2, suitable quantity of water is pressed in agitator tank 2 using water tank 7, opened
Agitating device 21 is stirred；
(3) slurry in agitator tank 2 enters sucking filtration in filter 3, and the filtrate containing microorganism and organic molecule passes through liquid
Collection device 5 is collected；
(4) first air inlets 11 are passed through gas in agitator tank 2, and bring deodorization in odor removal 6 into；Meanwhile, filter 3
And the gas in fluid collection device 5 is passed through deodorization in odor removal 6.
Claims (9)
1. a kind of microorganism in sample and organic molecule rapidly and efficiently segregation apparatuss, it is characterised in that：Including casing (1), with
And the agitator tank (2) in casing (1), filter (3), compression pump (4), fluid collection device (5), odor removal (6), storage
Water pot (7), agitator tank (2), filter (3), compression pump (4), fluid collection device (5) are sequentially connected；Divide on the casing (1)
The first air inlet (11), the second air inlet (12), the first gas outlet (13), the second gas outlet (14) are not provided with, described second enters
QI KOU (12), the second gas outlet (14) connect respectively with inside casing (1)；First air inlet (11) and agitator tank (2)
Air inlet connects, the gas outlet of agitator tank (2), the gas outlet of filter (3), fluid collection device (5) gas outlet respectively with
Odor removal (6) connects, and the gas outlet of odor removal (6) is connected with the first gas outlet (13)；It is provided with the agitator tank (2) and stirs
Mix in device (21), filter (3) and be provided with drainage screen (31)；The water tank (7) respectively with the first air inlet (11) and stirring
The air inlet connection of tank (2).
2. microorganism in a kind of sample according to claim 1 and organic molecule rapidly and efficiently segregation apparatuss, its feature
It is：Also include sterilizing lamp (8), the sterilizing lamp (8) is in casing (1).
3. microorganism in a kind of sample according to claim 1 and organic molecule rapidly and efficiently segregation apparatuss, its feature
It is：Also include temperature control equipment (9), the temperature control equipment (9) is in casing (1).
4. microorganism in a kind of sample according to claim 1 and organic molecule rapidly and efficiently segregation apparatuss, its feature
It is：Also include first gas defecator (15) and second gas defecator (16), the first gas defecator
(15) it is connected with the first air inlet (11), the second air inlet (12) respectively, the second gas defecator (16) is respectively with
One gas outlet (13), the second gas outlet (14) connection；First gas defecator (15) is passed through pure gases or two or more
Mixed gas.
5. microorganism in a kind of sample according to claim 1 and organic molecule rapidly and efficiently segregation apparatuss, its feature
It is：Also include gas-detecting device (17), the gas-detecting device (17) respectively with the first gas outlet (13), the second outlet
Mouth (14) connection.
6. microorganism in a kind of sample according to claim 1 and organic molecule rapidly and efficiently segregation apparatuss, its feature
It is：The filter (3) is provided with the device for making material concussion to be filtered in filter (3).
7. microorganism in a kind of sample according to claim 1 and organic molecule rapidly and efficiently segregation apparatuss, its feature
It is：Multiple filtration net (31) is provided with the filter (3)；Drainage screen (31) is one group of filter be arrangeding in parallel from top to bottom
Net, its aperture is sequentially reduced from top to bottom；Or drainage screen (31) is to be obliquely installed from top to bottom one group of filter screen, adjacent screen side
Edge is abutted against or is not abutted against, and its aperture is sequentially reduced from top to bottom；Drainage screen (31) is flat screen, or middle part is to lower recess,
Or middle part raises up.
8. microorganism in a kind of sample according to claim 1 and organic molecule rapidly and efficiently segregation apparatuss, its feature
It is：The fluid collection device (5) includes one group of receiving flask being arranged in series (51), the rubber stopper of sealing receiving flask (51)
(52) the sterilization plug (54) for, wrapping up rubber stopper (52), the syringe needle (53) for receiving flask (51) series connection inserted in plug (52),
Syringe needle (53) is big needle for inserting bottle for infusion；Cotton ball soaked in alcohol is provided with sterilization plug (54).
9. microorganism in a kind of sample according to claim 1 and organic molecule rapidly and efficiently segregation apparatuss, its feature
It is：The odor removal (6) includes air inlet pipe (61) and escape pipe (62)；The gas outlet of air inlet pipe (61) fills positioned at deodorization
(6) bottom is put, the gas feed of escape pipe (62) is located at odor removal (6) top.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621100677.3U CN206173343U (en) | 2016-09-30 | 2016-09-30 | Microorganism and organic molecule high efficiency separator in sample |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621100677.3U CN206173343U (en) | 2016-09-30 | 2016-09-30 | Microorganism and organic molecule high efficiency separator in sample |
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| Publication Number | Publication Date |
|---|---|
| CN206173343U true CN206173343U (en) | 2017-05-17 |
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| CN201621100677.3U Active CN206173343U (en) | 2016-09-30 | 2016-09-30 | Microorganism and organic molecule high efficiency separator in sample |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106367329A (en) * | 2016-09-30 | 2017-02-01 | 天益健康科学研究院（镇江）有限公司 | High-speed efficient separation device for microorganisms and organic molecules in sample |
| CN110144290A (en) * | 2019-06-06 | 2019-08-20 | 广州承葛生物科技有限公司 | A kind of filter for the separation of intestines bacterium |
| CN111801150A (en) * | 2018-03-19 | 2020-10-20 | 株式会社村田制作所 | Filter filter and filter device |
| CN112742096A (en) * | 2021-01-14 | 2021-05-04 | 淮阴师范学院 | Intestinal content liquid dung separating and extracting device |
-
2016
- 2016-09-30 CN CN201621100677.3U patent/CN206173343U/en active Active
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106367329A (en) * | 2016-09-30 | 2017-02-01 | 天益健康科学研究院（镇江）有限公司 | High-speed efficient separation device for microorganisms and organic molecules in sample |
| CN111801150A (en) * | 2018-03-19 | 2020-10-20 | 株式会社村田制作所 | Filter filter and filter device |
| CN110144290A (en) * | 2019-06-06 | 2019-08-20 | 广州承葛生物科技有限公司 | A kind of filter for the separation of intestines bacterium |
| CN112742096A (en) * | 2021-01-14 | 2021-05-04 | 淮阴师范学院 | Intestinal content liquid dung separating and extracting device |
| CN112742096B (en) * | 2021-01-14 | 2022-06-10 | 淮阴师范学院 | Intestinal content liquid dung separating and extracting device |
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