CN208876559U - A kind of full-automatic whole blood acquisition separation system - Google Patents
A kind of full-automatic whole blood acquisition separation system Download PDFInfo
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- CN208876559U CN208876559U CN201820611091.6U CN201820611091U CN208876559U CN 208876559 U CN208876559 U CN 208876559U CN 201820611091 U CN201820611091 U CN 201820611091U CN 208876559 U CN208876559 U CN 208876559U
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Abstract
Originally practical to be related to a kind of full-automatic whole blood acquisition separation system, seperator and disposable whole blood collecting and separating device are acquired including whole blood, the disposable whole blood collecting and separating device includes hemostix, sampler bag, biofilter, anti-coagulants pipeline, anti-coagulants puncture outfit, rbc preservative puncture outfit, salt water puncture outfit, Red Blood Cells Suspension bag, leucocyte filter, remove white Red Blood Cells Suspension bag, pressure detector connector, blood pump pipeline, Centrifuge Cup, plasma bags, cryoprecipitate spare bag and waste fluid bag, the whole blood acquisition seperator includes anticoagulant pump, blood pump, centrifuge, haemocyte detector, loine pressure detector, anti-coagulants air detectors, blood air detectors, blood plasma scale and controller；This practical automatic collection whole blood simultaneously separates and is prepared into fresh plasma and Red Blood Cells Suspension (or Washed Red Blood Cells), and operating process is once completed, and is completed in two steps without that will acquire and separate to prepare, cost is relatively low and guarantee whole blood it is in vitro after plasma purity.
Description
Technical field
The utility model relates to a kind of blood collection separator, in particular to a kind of full-automatic whole blood acquisition point
From system.
Background technique
Component blood transfusion is the progress with medical science and medical technology, newly general in nearly blood transfusion to grow up in more than 20 years
It reads.The emergence and development of component blood transfusion are a milestones of modern transfusion science progress.Component blood transfusion is substantially better than whole blood infusion.
Advanced country, the world today seldom directly uses whole blood, and component blood transfusion has been the direction of world today's blood transfusion career development.?
Whole blood separates and is prepared into various composition blood as the raw material blood for preparing various blood constituents, be used further to clinical patient；Fresh blood
Slurry, Red Blood Cells Suspension (or Washed Red Blood Cells) and cryoprecipitate are three kinds of component bloods therein.
Existing whole blood acquisition and separation and preparation technology are completed in two places respectively.
First place, Blood Sampling Room: hemostix is punctured the vein for being needled into blood donor's arm by whole blood acquisition, technical staff
In, it flows into whole blood in storage bag through conduit, a certain amount of anti-coagulants anticoagulant for storage of whole blood is contained in storage bag, to prevent collection
Blood clotting.After the whole blood (for example, 400ml, 300ml or 200ml) that blood donor collects fixed volume, whole blood is placed into 2-6
DEG C refrigerator saves.Technical staff repeats the above process, and acquires the blood of several blood donors, after the completion of waiting collecting works, transfer at
Separation preparation place.
Second place, ingredient separate preparation room: whole blood bag is put into large capacity centrifuge by technical staff, high speed rotation
Whole blood, is separated into the blood constitutents such as the blood plasma on upper layer and the red blood cell of lower layer by centrifugation in bag.Then by blood bag from centrifuge
In gently take out, and whole blood bag is transferred in the devices such as plasma-separating clip or blood component separator, by the blood of blood bag at the middle and upper levels
Slurry squeezes out, and is separated to blood plasma collecting bag, and red blood cell stays in former blood bag, then alserver's solution is injected in red blood cell, preparation
At Red Blood Cells Suspension.After above-mentioned some processing, then by blood plasma and red cell suspension etc., individually blood constituent is stored separately
In different temperatures.
The method of current art, as previously discussed: needing more places (two places of blood sampling and separation preparation), how artificial (complete
Blood collector and blood separate preparation personnel), more equipment (hemostix, large capacity centrifuge, blood component separator or point slurry
Folder), meanwhile, whole blood is transported to blood separation preparation room from Blood Sampling Room, and before carrying out separation preparation, whole blood must be stored up to several
Hour, influence the quality of blood constituent, or even the opportunity beyond preparation fresh frozen plasma and cryoprecipitate.
Utility model content
Purpose of the utility model is to solve above-mentioned existing defect, a kind of certifiable whole blood is provided and leaves human body
Afterwards, fresh plasma and Red Blood Cells Suspension (or Washed Red Blood Cells) are isolated with prestissimo, improves plasma purity, it is cold heavy to prepare
The full-automatic whole blood of shallow lake offer condition acquires separation system.
To achieve the above object, the technical solution of the utility model is as follows:
A kind of full-automatic whole blood acquires separation system, which is characterized in that acquires seperator and disposable including whole blood
Whole blood collecting and separating device,
Wherein, the disposable whole blood collecting and separating device includes hemostix, sampler bag, biofilter, anti-coagulants pipe
Road, anti-coagulants puncture outfit, rbc preservative puncture outfit, salt water puncture outfit, Red Blood Cells Suspension bag, leucocyte filter, go it is white
Red Blood Cells Suspension bag, pressure detector connector, blood pump pipeline, Centrifuge Cup, plasma bags, cryoprecipitate spare bag and waste fluid bag, it is described
Hemostix, biofilter, anti-coagulants pipeline and anti-coagulants puncture outfit pass sequentially through blood transfusion pipeline connect, the hemostix with carefully
Threeway one and threeway two are successively connected between bacterium filter, the lower port of the threeway one, which connects, sets sampler bag, and the anti-coagulants is worn
Successively be connected to threeway three between thorn device and anti-coagulants pipeline, the side ports of the threeway three by blood transfusion pipeline divide two-way respectively with
Rbc preservative puncture outfit is connected with salt water puncture outfit, and the upper port of the threeway two is successively connected to blood pump by pipeline of transfusing blood
Pipeline, Centrifuge Cup and plasma bags are successively connected to threeway four and threeway on the blood transfusion pipeline between the threeway two and blood pump pipeline
Five, the side ports of the threeway four are connected to by pipeline of transfusing blood with the Single port of Red Blood Cells Suspension bag, the Red Blood Cells Suspension bag
Another port by transfuse blood pipeline be connected to white Red Blood Cells Suspension bag is removed, the Red Blood Cells Suspension bag and go it is white suspension it is red carefully
Born of the same parents bag it is sets leucocyte filter indirectly, the pressure detector connector is connect with the side ports of threeway five, the plasma bags and
It being connect on blood transfusion pipeline between Centrifuge Cup and sets threeway six, the side ports of the threeway six are connected to by pipeline of transfusing blood with waste fluid bag,
One end of the plasma bags is connected to by pipeline of transfusing blood with cryoprecipitate spare bag；
The whole blood acquisition seperator includes anticoagulant pump, blood pump, centrifuge, haemocyte detector, loine pressure detection
Device, anti-coagulants air detectors, blood air detectors, blood plasma scale and controller, the anti-coagulants pipeline connect in anticoagulant pump
On, the blood pump pipeline connects on blood pump, and the Centrifuge Cup is mounted in centrifuge, and the haemocyte detector connects in Centrifuge Cup
On blood transfusion pipeline between plasma bags, the pressure detector connector is mounted on loine pressure detector, the anti-coagulants
Air detectors connect on the blood transfusion pipeline between anticoagulant pump pipeline and threeway three, and the blood air detectors connect in threeway
On blood transfusion pipeline between five and Centrifuge Cup, the plasma bags are mounted on blood plasma scale, the haemocyte detector, loine pressure
Detector, anti-coagulants air detectors, blood air detectors and blood plasma scale signal output end respectively with the signal of controller
Input terminal connection, the signal output end of the controller are connect with the signal input part of anticoagulant pump, blood pump and centrifuge respectively.
Further include as a preferred technical solution, be mounted on blood transfusion pipeline on control valve, the control valve include valve one,
Valve two, valve three, valve four, valve five, valve six and valve seven connect on the blood transfusion pipeline between the threeway one and threeway two and set valve one, institute
State anti-coagulants puncture outfit, rbc preservative puncture outfit and salt water puncture outfit and transfuse blood pipeline connecting pin connect respectively set valve two,
Valve three and valve four connect on the blood transfusion pipeline between the threeway six and plasma bags and set valve five, between the threeway six and waste fluid bag
Blood transfusion pipeline on connect and set valve six, connect on the blood transfusion pipeline between the threeway four and Red Blood Cells Suspension bag and set valve seven, the control
The signal input part of valve processed is connect with the signal output end of controller respectively.
The anti-coagulants puncture outfit, rbc preservative puncture outfit and salt water puncture outfit point as a preferred technical solution,
Not to input anti-coagulants, rbc preservative and salt water into blood transfusion pipeline, wherein anti-coagulants is deposited by peripheral hardware anti-coagulants bag
Storage, anti-coagulants bag are mounted on anti-coagulants scale.
As a preferred technical solution, the volume size of the Centrifuge Cup set acquisition blood donor's target whole blood volume as
400ml, 300ml and 200ml.
The utility model has the following beneficial effects:
1, it mainly solves existing whole blood to collect in separation preparation, when useless there are process, laborious, more places are at high cost；
2, after guaranteeing that whole blood is in vitro, fresh plasma and Red Blood Cells Suspension (or Washed Red Blood Cells) are isolated with prestissimo,
Freezing in time, the as far as possible rate of decay of the instability factor in reduction blood plasma, improve plasma purity, provide for preparation cryoprecipitate
Condition；
3, reduce separation preparation link in place, the large scale equipments such as large capacity centrifuge and blood component separator,
Facility, save the cost.
Detailed description of the invention
Fig. 1 is the structural block diagram that a kind of full-automatic whole blood of the utility model acquires separation system；
Fig. 2 is a kind of this practical structural schematic diagram of full-automatic whole blood acquisition separation system.
In figure: 1- hemostix, 2- sampler bag, 3- biofilter, 4- anti-coagulants pipeline, 5- anti-coagulants puncture outfit, 6- are red
Cell maintenance liquid puncture outfit, 7- salt water puncture outfit, 8- Red Blood Cells Suspension bag, 9- leucocyte filter, 10- remove white Red Blood Cells Suspension
Bag, 11- pressure detector connector, 12- blood pump pipeline, 13- Centrifuge Cup, 14- plasma bags, 15- cryoprecipitate spare bag, 16- waste liquid
Bag, 17- threeway one, 18- threeway two, 19- threeway three, 20- threeway four, 21- threeway five, 22- threeway six, 23- anticoagulant pump,
24- blood pump, 25- centrifuge, 26- haemocyte detector, 27- loine pressure detector, 28- anti-coagulants air detectors, 29- blood
Liquid air detectors, 30- blood plasma scale, 31- controller, 32- anti-coagulants scale, 33- valve one, 34- valve two, 35- valve three, 36- valve four,
37- valve five, 38- valve six, 39- valve seven.
Specific embodiment
To make the structure feature to the utility model and the effect of being reached has a better understanding and awareness, to compared with
Good examples and drawings cooperate detailed description, are described as follows:
As shown in Fig. 1~2, a kind of full-automatic whole blood acquisition separation system, including whole blood acquire seperator and disposably make
With whole blood collecting and separating device,
Wherein, disposable whole blood collecting and separating device includes hemostix 1, sampler bag 2, biofilter 3, anti-coagulants pipeline
4, anti-coagulants puncture outfit 5, rbc preservative puncture outfit 6, salt water puncture outfit 7, Red Blood Cells Suspension bag 8, leucocyte filter 9,
Remove white Red Blood Cells Suspension bag 10, pressure detector connector 11, blood pump pipeline 12, Centrifuge Cup 13, plasma bags 14, cryoprecipitate spare bag
15 and waste fluid bag 16, hemostix 1, biofilter 3, anti-coagulants pipeline 4 and anti-coagulants puncture outfit 5 pass sequentially through blood transfusion pipeline and connect
It connects, threeway 1 and threeway 2 18 is successively connected between hemostix 1 and biofilter 3, the lower port of threeway 1 connects to set and adopt
Sample bag 2, is successively connected to threeway 3 19 between anti-coagulants puncture outfit 5 and anti-coagulants pipeline 4, the side ports of threeway 3 19 pass through blood transfusion
Pipeline divides two-way to connect respectively with rbc preservative puncture outfit 6 and salt water puncture outfit 7, and the upper port of threeway 2 18 passes through blood transfusion
Pipeline is successively connected to blood pump pipeline 12, Centrifuge Cup 13 and plasma bags 14, the blood transfusion pipeline between threeway 2 18 and blood pump pipeline 12
On be successively connected to threeway 4 20 and threeway 5 21, the side ports of threeway 4 20 pass through blood transfusion pipeline and Red Blood Cells Suspension bag 8 one
The another port of port connection, Red Blood Cells Suspension bag 8 is connected to by pipeline of transfusing blood with white Red Blood Cells Suspension bag 10 is removed, red suspending
Cell bags 8 and go white Red Blood Cells Suspension bag 10 is to set leucocyte filter 9 indirectly, pressure detector connector 11 and threeway 5 21
Side ports connect, and connect on the blood transfusion pipeline between plasma bags 14 and Centrifuge Cup 13 and set threeway 6 22, and the side ports of threeway 6 22 are logical
It crosses blood transfusion pipeline to be connected to waste fluid bag 16, one end of plasma bags 14 is connected to by pipeline of transfusing blood with cryoprecipitate spare bag 15；
It includes anticoagulant pump 23, blood pump 24, centrifuge 25, haemocyte detector 26, loine pressure that whole blood, which acquires seperator,
Detector 27, anti-coagulants air detectors 28, blood air detectors 29, controller 31 and blood plasma scale 30, anti-coagulants pipeline 4 connect
On anticoagulant pump 23, blood pump pipeline 12 is connect on blood pump 24, and Centrifuge Cup 13 is mounted in centrifuge 25, haemocyte detector 26
It connects on the blood transfusion pipeline between Centrifuge Cup 13 and plasma bags 14, pressure detector connector 11 is mounted on loine pressure detector 27
On, anti-coagulants air detectors 28 connect on the blood transfusion pipeline between anticoagulant pump pipeline 4 and threeway 3 19, blood air detection
Device 29 connects on the blood transfusion pipeline between threeway 5 21 and Centrifuge Cup 13, and plasma bags 14 are mounted on blood plasma scale 30, and haemocyte is visited
The signal for surveying device 26, loine pressure detector 27, anti-coagulants air detectors 28, blood air detectors 29 and blood plasma scale 30 is defeated
Outlet is connect with the signal input part of controller 31 respectively, the signal output end of controller 31 respectively with anticoagulant pump 23, blood pump
24 connect with the signal input part of centrifuge 25.
In the present embodiment, further include be mounted on blood transfusion pipeline on control valve, control valve include valve 1, valve 2 34,
Valve 3 35, valve 4 36, valve 5 37, valve 6 38 and valve 7 39 connect on the blood transfusion pipeline between threeway 1 and threeway 2 18 and set valve
One 33, the connecting pin of anti-coagulants puncture outfit 5, rbc preservative puncture outfit 6 and salt water puncture outfit 7 and pipeline of transfusing blood connects set respectively
Valve 2 34, valve 3 35 and valve 4 36 connect on the blood transfusion pipeline between threeway 6 22 and plasma bags 14 and set valve 5 37, threeway 6 22 with
It is connect on blood transfusion pipeline between waste fluid bag 16 and sets valve 6 38, connect on the blood transfusion pipeline between threeway 4 20 and Red Blood Cells Suspension bag 8
If valve 7 39, the signal input part of control valve is connect with the signal output end of controller 31 respectively.
In the present embodiment, anti-coagulants puncture outfit 5, rbc preservative puncture outfit 6 and salt water puncture outfit 7 respectively to
The interior input anti-coagulants of pipeline of transfusing blood, rbc preservative and salt water, wherein anti-coagulants is stored by peripheral hardware anti-coagulants bag, anticoagulant
Agent bag is mounted on anti-coagulants scale 32.
In the present embodiment, the volume size of Centrifuge Cup 13 set acquisition blood donor's target whole blood volume as 400ml,
300ml and 200ml.
In the present embodiment, the working principle of this system are as follows: the success of pin puncture blood donor forearm vein is punctured on hemostix 1
Afterwards, it opens whole blood and acquires seperator, centrifuge 25 drives Centrifuge Cup 13 to bring into operation, and anticoagulant pump 23 and blood pump 24 turn clockwise
It starts building to make, at the same time, controller 31 opens valve 1, valve 2 34, valve 5 37 and valve 6 38, remaining valve is closed；Blood donor's
Whole blood enters in blood transfusion pipeline, and anti-coagulants forms anticoagulated whole blood after mixing at threeway 2 18 with the whole blood of extraction, then passes through
Threeway 4 20 and threeway 5 21 are sent into Centrifuge Cup 13 by blood pump 24 to be centrifuged, and obtains fresh plasma entrance after separation
In plasma bags 14；Whole blood is quantified according to the revolution of blood pump 24 measurement acquisition blood donor and the measurement separation and quantitative blood plasma of blood plasma scale 30 is complete
At later, blood collection stops, and anticoagulant pump 23 and blood pump 24 shut down, and all valves are closed, and centrifuge 25 brakes；Wait be centrifuged
Machine 25 stops, and anticoagulant pump 23 rotates clockwise, and blood pump 24 rotates counterclockwise, and valve 7 39, valve 5 37 and valve 2 34 are opened, remaining
Valve is closed, other blood constituents and alserver's solution in Centrifuge Cup 13 in addition to blood plasma, enter to Red Blood Cells Suspension at this time
In bag 8, and then again by the filtering of leucocyte filter 9 to going in white Red Blood Cells Suspension bag 10, be prepared into leucocyte-removing suspend it is red
Cell；It is then after blood collection stopping, centrifuge 25 continues to run, anticoagulant pump 23 and blood if you need to prepare Washed Red Blood Cells
Pump 24 rotates clockwise, and valve 6 38 and valve 4 36 are opened, remaining valve is closed, salt water by anticoagulant pump 23 and blood pump 24 enter from
Heart cup 13 displaces the non-red blood cell component of nearly all plasma composition and part in Centrifuge Cup 13, and is vented to waste fluid bag
In, above-mentioned Red Blood Cells Suspension preparation process is then repeated, can be prepared into Washed Red Blood Cells.
In conclusion the preferred embodiment of only the utility model, is not used to limit the utility model implementation
Range, all equivalent changes according to carried out by shape described in the utility model claims range, construction, feature and spirit with repair
Decorations, should be included in the scope of the claims of the utility model.
Claims (4)
1. a kind of full-automatic whole blood acquires separation system, which is characterized in that acquire seperator and disposable complete including whole blood
Blood collecting and separating device,
Wherein, the disposable whole blood collecting and separating device includes hemostix, sampler bag, biofilter, anti-coagulants pipeline, resists
Solidifying agent puncture outfit, salt water puncture outfit, Red Blood Cells Suspension bag, leucocyte filter, goes white suspension red at rbc preservative puncture outfit
Cell bags, pressure detector connector, blood pump pipeline, Centrifuge Cup, plasma bags, cryoprecipitate spare bag and waste fluid bag, the hemostix,
Biofilter, anti-coagulants pipeline and anti-coagulants puncture outfit pass sequentially through blood transfusion pipeline and connect, the hemostix and bacteriological filter
Threeway one and threeway two are successively connected between device, the lower port of the threeway one, which connects, sets sampler bag, the anti-coagulants puncture outfit with
Successively be connected to threeway three between anti-coagulants pipeline, the side ports of the threeway three by pipeline of transfusing blood divide two-way respectively with red blood cell
Precerving liquid puncture outfit is connected with salt water puncture outfit, the upper port of the threeway two by pipeline of transfusing blood successively be connected to blood pump pipeline,
Centrifuge Cup and plasma bags are successively connected to threeway four and threeway five, institute on the blood transfusion pipeline between the threeway two and blood pump pipeline
The side ports of threeway four are stated to be connected to by pipeline of transfusing blood with the Single port of Red Blood Cells Suspension bag, the Red Blood Cells Suspension bag it is another
Port by transfuse blood pipeline be connected to white Red Blood Cells Suspension bag is removed, the Red Blood Cells Suspension bag with go white Red Blood Cells Suspension bag it
Leucocyte filter is set indirectly, the pressure detector connector is connect with the side ports of threeway five, the plasma bags and Centrifuge Cup
Between blood transfusion pipeline on connect and set threeway six, the side ports of the threeway six are connected to by pipeline of transfusing blood with waste fluid bag, the blood
One end of slurry bag is connected to by pipeline of transfusing blood with cryoprecipitate spare bag,
The whole blood acquisition seperator includes anticoagulant pump, blood pump, centrifuge, haemocyte detector, loine pressure detector, resists
Solidifying agent air detectors, blood air detectors, blood plasma scale and controller, the anti-coagulants pipeline connect on anticoagulant pump, institute
It states blood pump pipeline to connect on blood pump, the Centrifuge Cup is mounted in centrifuge, and the haemocyte detector connects in Centrifuge Cup and blood
It starches on the blood transfusion pipeline between bag, the pressure detector connector is mounted on loine pressure detector, the anti-coagulants air
Detector connects on the blood transfusion pipeline between anticoagulant pump pipeline and threeway three, the blood air detectors connect threeway five with
On blood transfusion pipeline between Centrifuge Cup, the plasma bags are mounted on blood plasma scale, the haemocyte detector, loine pressure detection
Device, anti-coagulants air detectors, blood air detectors and blood plasma scale signal output end inputted respectively with the signal of controller
End connection, the signal output end of the controller are connect with the signal input part of anticoagulant pump, blood pump and centrifuge respectively.
2. a kind of full-automatic whole blood according to claim 1 acquires separation system, it is characterised in that: further include be mounted on it is defeated
Control valve on blood vessel line, the control valve include valve one, valve two, valve three, valve four, valve five, valve six and valve seven, the threeway one
It is connect on blood transfusion pipeline between threeway two and sets valve one, the anti-coagulants puncture outfit, rbc preservative puncture outfit and salt water are worn
The connecting pin of thorn device and pipeline of transfusing blood connects respectively sets valve two, valve three and valve four, the blood transfusion tube between the threeway six and plasma bags
It is connect on line and sets valve five, connect on the blood transfusion pipeline between the threeway six and waste fluid bag and set valve six, the threeway four is red thin with suspension
It is connect on blood transfusion pipeline between born of the same parents' bag and sets valve seven, the signal input part of the control valve connects with the signal output end of controller respectively
It connects.
3. a kind of full-automatic whole blood according to claim 2 acquires separation system, it is characterised in that: the anti-coagulants punctures
Device, rbc preservative puncture outfit and salt water puncture outfit are respectively to input anti-coagulants, rbc preservative into blood transfusion pipeline
And salt water, wherein anti-coagulants is stored by peripheral hardware anti-coagulants bag, and anti-coagulants bag is mounted on anti-coagulants scale.
4. a kind of full-automatic whole blood according to claim 1 acquires separation system, it is characterised in that: the appearance of the Centrifuge Cup
Product size sets the volume of acquisition blood donor's target whole blood as 400ml, 300ml and 200ml.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201820611091.6U CN208876559U (en) | 2018-04-26 | 2018-04-26 | A kind of full-automatic whole blood acquisition separation system |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201820611091.6U CN208876559U (en) | 2018-04-26 | 2018-04-26 | A kind of full-automatic whole blood acquisition separation system |
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| CN208876559U true CN208876559U (en) | 2019-05-21 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108577863A (en) * | 2018-04-26 | 2018-09-28 | 江苏伯纳德生物科技发展有限公司 | A kind of full-automatic whole blood acquisition piece-rate system |
| CN113289091A (en) * | 2021-03-29 | 2021-08-24 | 马永庆 | Special blood collection bag for umbilical cord blood and matched collection equipment thereof |
| WO2023024166A1 (en) * | 2021-08-25 | 2023-03-02 | 赛若麦得（上海）生物技术有限公司 | Plasma collector |
-
2018
- 2018-04-26 CN CN201820611091.6U patent/CN208876559U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108577863A (en) * | 2018-04-26 | 2018-09-28 | 江苏伯纳德生物科技发展有限公司 | A kind of full-automatic whole blood acquisition piece-rate system |
| CN113289091A (en) * | 2021-03-29 | 2021-08-24 | 马永庆 | Special blood collection bag for umbilical cord blood and matched collection equipment thereof |
| WO2023024166A1 (en) * | 2021-08-25 | 2023-03-02 | 赛若麦得（上海）生物技术有限公司 | Plasma collector |
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