CN113289091A - Special blood collection bag for umbilical cord blood and matched collection equipment thereof - Google Patents

Special blood collection bag for umbilical cord blood and matched collection equipment thereof Download PDF

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Publication number
CN113289091A
CN113289091A CN202110729510.2A CN202110729510A CN113289091A CN 113289091 A CN113289091 A CN 113289091A CN 202110729510 A CN202110729510 A CN 202110729510A CN 113289091 A CN113289091 A CN 113289091A
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China
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cord blood
anticoagulant
umbilical cord
blood
bag
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CN202110729510.2A
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Chinese (zh)
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马永庆
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Individual
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Individual
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/04Liquids
    • A61M2202/0413Blood
    • A61M2202/0462Placental blood, umbilical cord blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3331Pressure; Flow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3379Masses, volumes, levels of fluids in reservoirs, flow rates

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Abstract

The invention discloses a special umbilical cord blood collection bag and an umbilical cord blood collection device, wherein the special umbilical cord blood collection bag comprises a blood collection needle, a first pipeline, a second pipeline, a main pipeline, an anticoagulant bag and a blood bag; the one end of first pipeline with the blood taking needle is connected, the one end of second pipeline with the anticoagulant bag is connected, be equipped with the anticoagulant in the anticoagulant bag, first pipeline with the second pipeline joins the back and forms total pipeline, total pipeline terminal with the blood bag is connected. The umbilical cord blood collecting equipment comprises an umbilical cord blood peristaltic pump head, an umbilical cord blood peristaltic pump driver, an anticoagulant peristaltic pump head, an anticoagulant peristaltic pump driver, a high-frequency heat sealing machine head or a blood stopping and closing device. The special blood collection bag for the umbilical cord blood provided by the invention can be matched with an umbilical cord blood collection device for use, and can realize that: the anticoagulant is added according to the volume of the collected umbilical cord blood, so that the umbilical cord blood collecting time is shortened, the umbilical cord blood collecting amount is increased, the generation of clots is effectively reduced, and the operation of an umbilical cord blood collecting worker is simplified.

Description

Special blood collection bag for umbilical cord blood and matched collection equipment thereof
Technical Field
The invention relates to the technical field of umbilical cord blood sampling articles, in particular to a special umbilical cord blood sampling bag and umbilical cord blood sampling equipment.
Background
Umbilical cord blood is venous blood remaining in a placenta and an umbilical cord after a fetus is delivered and the umbilical cord is broken, is rich in stem cells, and is an important source of stem cells except bone marrow and peripheral blood. Umbilical cord blood is widely used clinically in the treatment of various blood diseases, hereditary and congenital diseases.
After the umbilical cord is broken, the umbilical cord blood in the placenta coagulates blood in a few minutes, and the optimal collection time of the umbilical cord blood is 1-2 minutes after the umbilical cord is broken. At present generally use venous blood collection bag to gather umbilical cord blood, the foetus is delivered to the navel to after breaking off, go into the umbilical vein with the blood taking needle puncture behind the disinfection umbilical cord, put the blood bag low, utilize the difference in height of placenta and blood collection bag, make umbilical cord blood flow income blood collection bag, concrete operating procedure is as follows:
preparing a blood collection bag: removing the blood bag, packaging, checking blood stasis, unscrewing the needle head, and preparing a disinfection bag;
disinfecting and puncturing: disinfecting an umbilical cord, disinfecting a puncture point by iodophor, and puncturing a blood taking needle into an umbilical vein;
collecting umbilical cord blood: fixing the blood taking needle by hands or hemostatic forceps, lowering the blood bag to have a height difference with the placenta, and continuously mixing the blood bag uniformly in the collection process;
and (5) finishing collection: when the umbilical cord is grey and sunken and no blood flows out, the blood stop is closed and the needle head is retracted.
The prior art has the following problems:
the collection amount is small: after the umbilical cord is broken, the umbilical cord blood coagulates in a few minutes, the time for collecting the umbilical cord blood is short, the umbilical cord blood can only flow downwards by gravity, the collecting flow rate is slow, the umbilical cord blood is not completely coagulated in the placenta, the collecting amount is small, and a large amount of umbilical cord blood is wasted in the placenta.
Mixing with the coagulum: in the later period of collection, the umbilical cord blood in the placenta and the umbilical cord begins to coagulate blood, and the small coagulated blood can enter a blood bag through the needle head, so that the subsequent detection and use are influenced.
The operation is inconvenient: when the umbilical cord blood is collected, one person needs to fix the umbilical cord and the blood taking needle, the blood bag needs to be lowered, and the blood bag is shaken while the umbilical cord blood is collected, so that the umbilical cord blood and the anticoagulant are fully mixed to prevent local coagulation, and the operation is inconvenient.
The activity is poor: because the volume of the anticoagulant in the venous blood recovery bag is fixed, a certain amount of venous blood is collected, and the volume of the umbilical cord blood which can be collected is not fixed. When the umbilical cord blood is collected less, the relative concentration of the anticoagulant is high, and the activity of umbilical cord blood cells is influenced; when the collection amount is too large, the anticoagulant is insufficient, and local blood coagulation appears.
Disclosure of Invention
Therefore, the invention provides a special blood collecting bag for umbilical cord blood and an umbilical cord blood collecting device, which aim to solve at least one of the above problems in the prior art.
In order to achieve the above purpose, the invention provides the following technical scheme:
according to the invention, the special blood collection bag for umbilical cord blood is provided, and comprises a blood collection needle, a first pipeline, a second pipeline, a main pipeline, an anticoagulant bag and a blood bag; the one end of first pipeline with the blood taking needle is connected, the one end of second pipeline with the anticoagulant bag is connected, be equipped with the anticoagulant in the anticoagulant bag, first pipeline with the second pipeline joins the back and forms total pipeline, total pipeline terminal with the blood bag is connected.
Furthermore, the anticoagulant is placed in the anticoagulant bag, the anticoagulant bag is separated from the blood bag, during the umbilical cord blood collection process, umbilical cord blood flows through the first pipeline, the anticoagulant flows into the blood bag after being converged in the main pipeline through the second pipeline, and a certain amount of anticoagulant is added according to the volume of the collected umbilical cord blood.
According to the invention, the umbilical cord blood collection equipment comprises an umbilical cord blood peristaltic pump head and an umbilical cord blood peristaltic pump driver, wherein the umbilical cord blood peristaltic pump head and the first pipeline of the special umbilical cord blood collection bag are combined into a complete peristaltic pump to provide power for umbilical cord blood collection.
Furthermore, the umbilical cord blood collection equipment also comprises an anticoagulant peristaltic pump head and an anticoagulant peristaltic pump driver, wherein the anticoagulant peristaltic pump head and the second pipeline of the special umbilical cord blood collection bag are combined into a complete peristaltic pump to provide power for the anticoagulant to flow into the blood bag.
Further, in the process of collecting the umbilical cord blood, the umbilical cord blood peristaltic pump driver controls the speed of collecting the umbilical cord blood; the anticoagulant peristaltic pump driver controls the adding speed of the anticoagulant, and 2 drivers rotate synchronously or according to a preset proportion to realize that the umbilical cord blood and the anticoagulant enter a main pipeline in proportion.
Further, the umbilical cord blood and the anticoagulant are converged in the main pipeline and are uniformly mixed in the flowing process, and the uniformly mixed umbilical cord blood and the anticoagulant flow into the blood bag.
Furthermore, in the umbilical cord blood collection process, the umbilical cord blood collection equipment collects rotation data of the umbilical cord blood peristaltic pump driver and the anticoagulant peristaltic pump driver, calculates the real-time umbilical cord blood collection amount and the real-time anticoagulant addition amount according to the rotation condition of the peristaltic pump driver, and stores the umbilical cord blood collection amount and the anticoagulant addition amount in the equipment to realize the data collection process.
The high-frequency heat sealing machine head or the blood stopping closing device is used for closing the main pipeline after the collection of the umbilical cord blood is completed.
The invention has the following advantages:
according to the special umbilical cord blood collection bag provided by the invention, the anticoagulant bag is separated from the blood bag, the anticoagulant is added in the process of collecting umbilical cord blood, a certain proportion of anticoagulant can be added according to the volume of collected umbilical cord blood, the activity of umbilical cord blood cells is ensured, in addition, additional power is provided, the umbilical cord blood is quickly collected into the blood collection bag, the umbilical cord blood collection amount is improved, the generation of clots is effectively reduced, the umbilical cord blood collection can be finished by one person, and the operation of an umbilical cord blood collection personnel is simplified. And the data acquisition process can be realized, and the key parameters in the acquisition process can be recorded.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below. It should be apparent that the drawings in the following description are merely exemplary, and that other embodiments can be derived from the drawings provided by those of ordinary skill in the art without inventive effort.
The structures, ratios, sizes, and the like shown in the present specification are only used for matching with the contents disclosed in the specification, so as to be understood and read by those skilled in the art, and are not used to limit the conditions that the present invention can be implemented, so that the present invention has no technical significance, and any structural modifications, changes in the ratio relationship, or adjustments of the sizes, without affecting the effects and the achievable by the present invention, should still fall within the range that the technical contents disclosed in the present invention can cover.
Fig. 1 is a schematic structural diagram illustrating a blood collection bag dedicated for umbilical cord blood according to an exemplary embodiment;
FIG. 2 is a schematic diagram of an umbilical cord blood collection apparatus according to an exemplary embodiment;
fig. 3 is a schematic structural diagram illustrating connection between the cord blood collection device and a blood collection bag dedicated for cord blood during use according to an exemplary embodiment.
In the figure: 11. a blood collection needle; 12. a first pipeline; 13. a second pipeline; 14. a main pipeline; 15. anticoagulant bags; 16. a blood bag; 17. a pump head of the umbilical cord blood peristaltic pump; 18. an umbilical cord blood peristaltic pump driver; 19. an anticoagulant peristaltic pump head; 20. an anticoagulant peristaltic pump driver; 21. high frequency heat sealing of the nose or blood stopping closure device.
Detailed Description
The present invention is described in terms of particular embodiments, other advantages and features of the invention will become apparent to those skilled in the art from the following disclosure, and it is to be understood that the described embodiments are merely exemplary of the invention and that it is not intended to limit the invention to the particular embodiments disclosed. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
According to an embodiment of the present invention, there is provided a special blood collection bag for umbilical cord blood, as shown in fig. 1, including a blood collection needle 11, a first pipeline 12, a second pipeline 13, a main pipeline 14, an anticoagulant bag 15, and a blood bag 16; one end of the first pipeline 12 is connected with the blood collection needle 11, one end of the second pipeline 13 is connected with the anticoagulant bag 15, anticoagulant is filled in the anticoagulant bag 15, the first pipeline 12 is formed after the second pipeline 13 is converged on the main pipeline 14, and the tail end of the main pipeline 14 is connected with the blood bag 16.
According to an embodiment of the present invention, there is provided an umbilical cord blood collection apparatus, as shown in fig. 2, including an umbilical cord blood peristaltic pump head 17, an umbilical cord blood peristaltic pump driver 18, an anticoagulant peristaltic pump head 19, an anticoagulant peristaltic pump driver 20, and a high-frequency heat sealing head or blood stopping closing device 21. The umbilical cord blood peristaltic pump head 17, the umbilical cord blood peristaltic pump driver 18 and a peristaltic pump pipe can be combined into a complete peristaltic pump; the anticoagulant peristaltic pump head 19, the anticoagulant peristaltic pump driver 20 and the peristaltic pump tube can be combined into a complete peristaltic pump.
According to the embodiment of the invention, the umbilical cord blood special-purpose blood collection bag is used in cooperation with an umbilical cord blood collection device, the connection mode is shown in fig. 3, the umbilical cord blood peristaltic pump head 17, the umbilical cord blood peristaltic pump driver 18 and the first pipeline 12 are used as peristaltic pump pipes to form an umbilical cord blood collection pump, the anticoagulant peristaltic pump head 19, the anticoagulant peristaltic pump driver 20 and the second pipeline 13 are used as peristaltic pump pipes to form an anticoagulant addition pump, and the high-frequency heat sealing machine head or the blood stopping closing device 21 is combined with the main pipeline 14.
Firstly, before umbilical cord blood collection, a special umbilical cord blood collection bag and an umbilical cord blood collection device are installed and connected as shown in fig. 3, and a peristaltic pump is composed of a first umbilical cord blood collection bag pipeline 12, an umbilical cord blood peristaltic pump head 17 of the umbilical cord blood collection device and an umbilical cord blood peristaltic pump driver 18; a second umbilical cord blood bag pipeline 13, an anticoagulant peristaltic pump head 19 of the umbilical cord blood collection equipment and an anticoagulant peristaltic pump driver 20 form a peristaltic pump; the umbilical cord blood collecting bag main pipeline 14 is combined with a high-frequency heat sealing machine head or a blood stopping closing device 21.
The installation is accomplished, uses blood taking needle 11 punctures the umbilical cord and inserts umbilical vein blood vessel, umbilical cord blood peristaltic pump driver 18 with anticoagulant peristaltic pump driver 20 begins to rotate according to predetermined speed, and the pump is gathered to the umbilical cord blood and begins work, and the umbilical cord blood passes through under the power that the pump was gathered to the umbilical cord blood first pipeline 12 the total pipeline 14 flows into in the blood bag 16, and the anticoagulant flows into the pump and begins work in step simultaneously, under the power that the anticoagulant inflow pump provided, the anticoagulant process second pipeline 13 the total pipeline 14 flows into in the blood bag 16.
During the collection process, the umbilical cord blood and the anticoagulant respectively flow into the main pipeline 14 at a certain speed under the action of the umbilical cord blood collection pump and the anticoagulant inflow pump, are continuously mixed during the flowing process, and flow into the blood bag after being uniformly mixed.
During collection, the speed of collecting umbilical cord blood can be adjusted by adjusting the peristaltic pump drive 17 for umbilical cord blood, and the speed of adding anticoagulant can be adjusted by adjusting the peristaltic pump drive 19 for anticoagulant. The umbilical cord blood peristaltic pump driver 17 and the anticoagulant peristaltic pump driver 19 rotate synchronously or in a preset proportion, so that the umbilical cord blood and the anticoagulant enter a main pipeline in proportion. The umbilical cord blood collecting equipment records rotation data of the umbilical cord blood peristaltic pump driver 17 and the anticoagulant peristaltic pump driver 19 in the collecting process, real-time umbilical cord blood collecting amount and anticoagulant adding amount can be calculated according to the rotation data of the drivers, the data collection process is realized, and the whole collecting process can be traced.
The cord blood collection equipment further comprises a high-frequency heat sealing machine head or blood stopping closing device 21, and the high-frequency heat sealing machine head or blood stopping closing device is used for closing the main pipeline 14 after collection of cord blood is completed, so that the pipeline is closed, and the use is convenient. The blood bag is sealed after the collection is finished, and the pollution caused by the communication of the blood bag and the outside after the collection is finished is avoided.
In the prior art, a pipeline is usually used for connecting the blood taking needle 11 and the blood bag 16, blood is taken by using gravity, the collection flow rate is slow, the effective collection time of cord blood is short, the collection amount of cord blood is small, and a large amount of cord blood is wasted. In addition, the conventional blood collecting bag is added with a fixed amount of anticoagulant in advance in the blood bag 16, so that the umbilical cord blood collection amount is small, the relative concentration of the anticoagulant is high, and the activity of stem cells is influenced; too large collection amount and insufficient anticoagulant, local blood coagulation appears.
According to the embodiment of the invention, the umbilical cord blood collecting pump and the anticoagulant adding pump are adopted, so that power can be provided for collecting umbilical cord blood, the umbilical cord blood can be collected quickly, waste caused by coagulation due to low collecting speed of the umbilical cord blood is avoided, the umbilical cord blood collecting amount is increased, and inconvenience in operation caused by lowering of a blood bag when the umbilical cord blood is collected by the blood bag can be avoided. Simultaneously, the collected umbilical cord blood and the anticoagulant are mixed in the main pipeline 14 and are uniformly mixed in the flowing process, so that the operation of continuously shaking the blood bag in the operation process is omitted.
According to the embodiment of the invention, the anticoagulant bag 15 and the blood bag 16 are separated, and the anticoagulant is mixed and added in the umbilical cord blood collection process, so that the anticoagulant with a certain proportion is added according to the volume of the collected umbilical cord blood, the activity of umbilical cord blood cells is ensured, and the coagulation of the umbilical cord blood is avoided.
In this embodiment, the collecting device collects data such as collecting time, collecting amount, volume of anticoagulant added and the like during the process of collecting umbilical cord blood and stores the data in the collecting device, so as to realize datamation and traceability of the collecting process. Compare manual control among the prior art, this embodiment has higher collection effect and collection efficiency.
Although the invention has been described in detail above with reference to a general description and specific examples, it will be apparent to one skilled in the art that modifications or improvements may be made thereto based on the invention. Accordingly, such modifications and improvements are intended to be within the scope of the invention as claimed.

Claims (9)

1. A special blood collection bag for umbilical cord blood is characterized by comprising a blood collection needle, a first pipeline, a second pipeline, a main pipeline, an anticoagulant bag and a blood bag; the one end of first pipeline with the blood taking needle is connected, the one end of second pipeline with the anticoagulant bag is connected, be equipped with the anticoagulant in the anticoagulant bag, first pipeline with the second pipeline joins the back and forms total pipeline, total pipeline terminal with the blood bag is connected.
2. The special blood collection bag for umbilical cord blood as claimed in claim 1, wherein anticoagulant is placed in the anticoagulant bag, the anticoagulant bag is separated from the blood bag, and the amount of anticoagulant can be added to the blood bag according to the requirement.
3. An umbilical cord blood collection device is characterized by comprising an umbilical cord blood collection peristaltic pump head, an umbilical cord blood collection peristaltic pump driver and a blood collection bag pipeline or a first pipeline of a blood collection bag special for umbilical cord blood in claim 1 to form a peristaltic pump, and power is provided for umbilical cord blood collection in the umbilical cord blood collection process.
4. The apparatus according to claim 3, further comprising an anticoagulant peristaltic pump head, an anticoagulant peristaltic pump driver, combined with the second tube of the blood collection bag of claim 1 to provide a peristaltic pump to power the flow of anticoagulant from the anticoagulant bag into the blood bag during the collection of umbilical cord blood.
5. The cord blood collection apparatus according to claim 3, further comprising a high frequency heat sealing head or blood stopping closure device which closes the main conduit after collection of cord blood is completed.
6. A blood collection bag according to claim 1, which is used together with the umbilical cord blood collection apparatus according to claim 3, wherein, during umbilical cord blood collection, umbilical cord blood flows in through the first tube, anticoagulant flows in through the second tube, the umbilical cord blood and anticoagulant are mixed together in the main tube and then flow into the blood bag, and the umbilical cord blood and anticoagulant are mixed together.
7. The cord blood collection device according to claim 3, wherein the collection device adjusts the speed of collecting cord blood by changing the speed of rotation of the peristaltic pump driver of cord blood during the collection of cord blood, and calculates the real-time collection amount of cord blood according to the rotation of the peristaltic pump driver, and stores the calculated amount in the cord blood collection device to realize the datamation of the collection process.
8. The apparatus according to claim 3, wherein the apparatus is capable of adjusting the flow rate and inflow amount of anticoagulant into the blood bag by changing the rotation speed of the anticoagulant peristaltic pump driver during the process of feeding anticoagulant into the blood bag, calculating the real-time amount of anticoagulant into the blood bag according to the rotation speed of the anticoagulant peristaltic pump driver, and storing the real-time amount of anticoagulant into the apparatus for realizing the data of the anticoagulant feeding process.
9. The cord blood collection apparatus of claim 3, wherein said peristaltic pump drive for cord blood and said peristaltic pump drive for anticoagulant can be rotated synchronously or in a predetermined ratio to achieve a desired ratio of cord blood to anticoagulant into the main conduit.
CN202110729510.2A 2021-03-29 2021-06-29 Special blood collection bag for umbilical cord blood and matched collection equipment thereof Pending CN113289091A (en)

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CN202110334386 2021-03-29
CN202110334386X 2021-03-29

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2404534Y (en) * 1999-09-08 2000-11-08 四川省南格尔医用器具有限公司 Disposable and interrupted blood sampling device with blood cells separation
CN201073458Y (en) * 2007-09-04 2008-06-18 山东威高集团医用高分子制品股份有限公司 One-time operation mononuclear cell collecting device
CN104338189A (en) * 2013-07-23 2015-02-11 布莱特维克公司 Apparatus for blood concentration
CN206597162U (en) * 2016-12-20 2017-10-31 上海输血技术有限公司 Blood bag for cord blood collection
CN208274779U (en) * 2017-07-25 2018-12-25 天津市博奥天盛塑材有限公司 Arterial blood line and hemodialysis system
CN208876559U (en) * 2018-04-26 2019-05-21 江苏伯纳德生物科技发展有限公司 A kind of full-automatic whole blood acquisition separation system

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2404534Y (en) * 1999-09-08 2000-11-08 四川省南格尔医用器具有限公司 Disposable and interrupted blood sampling device with blood cells separation
CN201073458Y (en) * 2007-09-04 2008-06-18 山东威高集团医用高分子制品股份有限公司 One-time operation mononuclear cell collecting device
CN104338189A (en) * 2013-07-23 2015-02-11 布莱特维克公司 Apparatus for blood concentration
CN206597162U (en) * 2016-12-20 2017-10-31 上海输血技术有限公司 Blood bag for cord blood collection
CN208274779U (en) * 2017-07-25 2018-12-25 天津市博奥天盛塑材有限公司 Arterial blood line and hemodialysis system
CN208876559U (en) * 2018-04-26 2019-05-21 江苏伯纳德生物科技发展有限公司 A kind of full-automatic whole blood acquisition separation system

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