CN205460112U - Separator is gathered to full -automatic whole blood - Google Patents
Separator is gathered to full -automatic whole blood Download PDFInfo
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- CN205460112U CN205460112U CN201620030708.6U CN201620030708U CN205460112U CN 205460112 U CN205460112 U CN 205460112U CN 201620030708 U CN201620030708 U CN 201620030708U CN 205460112 U CN205460112 U CN 205460112U
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Abstract
The utility model discloses a process including before arriving blood capacity taken with blood capacity taken arrives and after two stages of separator is gathered to full -automatic whole blood, whole blood collection separation. The process of wherein arriving blood capacity taken preceding includes the 1st step of blood sampling, and plasma is collected for the 3rd step to the 2nd step of separation, and the 4th step stops the blood sampling, still fails the red blood cell for the 5th step, collects the red blood cell for the 6th step, and the 7th step stops still to fail, and the 8th step begins the blood sampling, the process of arriving behind the blood capacity taken includes that the 9th step stops to take a blood sample, the 10th step of additional red blood cell, and plasma is collected for the 12nd step to the 11st step of separation replacement plasma, and the 13rd step stops to replenish, still fails the red blood cell for the 14th step, collects the red blood cell for the 15th step, and the 16th step is replenished plasma according to the amount of calculation, and the 17th step stops still defeatedly. This device and method have realized that whole blood collection separation is automatic, separation blood component accords with relevant standard, has the biggest utilization to the blood resource.
Description
Technical field
This utility model belongs to blood collection isolation technics, relates to the device that a kind of blood of human body collection separates,
Especially a kind of full-automatic collecting whole blood segregation apparatus.
Background technology
Blood is conveying oxygen, carbon dioxide, nutritional labeling in human body, and takes away metabolite, and maintenance is oozed
Pressure, acid-base value and electrolyte balance thoroughly, keeps the important substance of body temperature, defence microorganism intrusion etc..Blood
Liquid is made up of erythrocyte, leukocyte, platelet, blood plasma etc..Due to some disease, treatment has
Time need to patient's infused blood or blood constituent.
Along with the development of science and technology, the application of blood constituent is increasingly valued by the people, and which forms
Component blood transfusion.So-called component blood transfusion, it is simply that certain composition in blood is separated, makes higher concentration
Blood Preparations, be then defeated by the technology of corresponding goods according to the needs of different patients.
The advantage of component blood transfusion is that goods capacity is little, and concentration is high, purity is good, and therapeutic effect is good；Use safety,
Untoward reaction is few；The generation through Transfusion Transmission disease can be reduced；It is easy to preserve, easy to use；Comprehensive utilization,
Save blood resource.
First component blood transfusion technology subject matter to be solved be exactly the preparation of blood constituent.At present, composition
Method prepared by blood has two kinds: one to be single blood sampling composition, such as Plasma Pheresis/Apheresis Plasma, Platelets Pheresis/Apheresis platelets, singly adopts grain
Cell；Two is to utilize whole blood to separate.
The most single blood sampling composition is applied in certain scope, and it is right that the main source of component blood is also dependent on
The separation of whole blood, particularly blood plasma, erythrocyte and cryoprecipitate.
Existing collecting whole blood separation method is divided into two steps: one is to gather whole blood, and two is to separate whole blood.
This method needs to complete in different posies.
One is collection whole blood on Blood Sampling Room or blood-collecting car: the blood taking needle of blood bag is punctured entrance and offers by medical worker
The vein blood vessel of blood person's arm, the blood of blood donor flows into blood taking bag, and and blood taking bag through the blood taking tube of blood bag
In anticoagulant for storage of whole blood mixing anticoagulant, gather whole blood amount be generally 400mL or 300mL or 200mL.
After collecting whole blood, first putting into 2 DEG C～the Refrigerator store of 6 DEG C, treat that blood collection on duty is complete, concentration is handed over to
Become locellus separation prepared composition blood.
Two is to become locellus separation to prepare blood constituent: medical worker Blood Sampling Room is transferred come equipped with whole blood
Blood bag put in Large Copacity centrifuge so that it is high speed rotating, owing in blood, the proportion of heterogeneity is different,
Blood in blood bag is divided into blood plasma and the erythrocyte of lower floor on upper strata.Take out blood bag, blood bag is transferred to point
In slurry folder, then by blood bag blood plasma extrusion at the middle and upper levels, collect in plasma bags, erythrocyte is retained in former blood
Red Blood Cells Concentrate is obtained in Dai.
Existing method collection separation blood prepared composition blood exists needs many posies (above-mentioned Blood Sampling Room, composition
Room), Simulation Based On Multi-step (take a blood sample, separate), many equipment (blood collecting balance, centrifuge, plasma-separating clip etc.).Meanwhile, entirely
Blood is transported to into before locellus carries out separating preparation from Blood Sampling Room, through the storage of several hours, and can different journeys
Degree ground affects the quality of blood constituent, even beyond preparation fresh frozen plasma and the opportunity of cryoprecipitate.
Although the utility model patent that publication No. is CN 104667362 A and Authorization Notice No. are CN
Full-automatic collecting whole blood seperator and supporting disposably making disclosed in the utility model patent of 204582094 U
Separation whole blood can be automatically gathered with collecting and separating device.Exist not when above-mentioned blood constituent can be overcome to prepare
Foot.But owing to collecting whole blood amount is fixing (400mL or 300mL or 200mL), when blood donor is red carefully
When born of the same parents' specific volume is higher or on the low side, the method cannot ensure capacity and the hemocyte ratio of the Red Blood Cells Concentrate of separation
Hold the requirement meeting relevant national standard (such as GB 18469), and when blood donor's hematocrit value is on the low side
Also the yield of the compositions such as blood plasma can be reduced.Therefore the method practicality is poor.
Summary of the invention
The deficiency existed for above prior art, the utility model proposes one and can realize collecting whole blood and divide
From automatization, it is provided that separating blood constituent meets relevant criterion and have the complete of maximum utilization to blood resource
Automatically collecting whole blood segregation apparatus.The technical solution of the utility model is as follows: a kind of full-automatic collecting whole blood divides
From device, including single use collecting whole blood separate lines and full-automatic collecting whole blood separation equipment, described
Blood taking needle, connecting tube I, connector I, anticoagulant for storage of whole blood is had on single use collecting whole blood separate lines
Entrance, connecting tube II, separate cup, connecting tube III, plasma bags, erythrocyte bag, connecting tube IV, connector
II, connecting tube V, connecting tube VI；Have on described full-automatic collecting whole blood separation equipment blood pump, centrifuge,
Plasma tube detector, circuit air detector, blood person's valve, red blood cell tube valve, blood plasma weigher, red
Cytolytic dose scale；Wherein said blood taking needle is accessed separate lines by connecting tube I by connector I；Described blood
Liquid preserves liquid entrance and is accessed separate lines by connecting tube II by connector I；Separate cup by connecting tube III with
Plasma bags connects；Described erythrocyte bag (is accessed separate lines by connecting tube IV by connector II；Described connection
Part II is connected with connector II by connecting tube V.
Further, described plasma tube detector is positioned in the connecting tube III of separate cup and plasma bags.
Further, described circuit air detector is positioned in the connecting tube VI of blood pump and connector II.
Further, described blood person's valve is positioned in the connecting tube V of connector II and connector I.
Further, described red blood cell tube valve is positioned in the connecting tube IV of connector II and erythrocyte bag.
Further, described blood plasma weigher is positioned at plasma bags end, and described erythrocyte weigher is positioned at erythrocyte
Bag end.
Advantage of the present utility model and having the beneficial effect that:
This utility model can realize the automatization that collecting whole blood separates, and solves existing method and there are the many hilllocks of needs
Position (above-mentioned Blood Sampling Room, become locellus), Simulation Based On Multi-step (take a blood sample, separate), many equipment are (blood collecting balance, centrifugal
Machine, plasma-separating clip etc.) problem.Decrease whole blood and be transported to into, from Blood Sampling Room, the process that locellus carries out separating,
Be conducive to improving the quality of blood constituent, be conducive to preparation fresh frozen plasma and cryoprecipitate.And gather separation
Blood constituent from method, ensure that it meets the requirement of relevant criterion.
Accompanying drawing explanation
Fig. 1 is the structural representation of this utility model device composition.
Fig. 2 is the flow chart that this utility model provides that preferred embodiment collecting whole blood separates.
In Fig. 1: 1. pipeline, 2. equipment, 3. blood taking needle, 4. connecting tube I, 5. connector I, 6. blood preseration
Liquid entrance, 7. connecting tube II, 8. separate cup, 9. connecting tube III, 10. plasma bags, 11. erythrocyte bags, 12. even
Adapter IV, 13. connectors II, 14. connecting tubes V, 15. connecting tubes six, 16. blood pumps, 17. centrifuges, 18. blood
Slurry pipeline detector, 19. circuit air detectors, 20. blood person's valves, 21. red blood cell tube valves, 22. blood plasma meters
Amount scale, 23. erythrocyte weighers.
In Fig. 2: 1. blood sampling, 2. separate, 3. collect blood plasma, 4. stop blood sampling, 5. go back red cells transfusion, 6. collect
Erythrocyte, 7. stops the most defeated, 8. starts blood sampling, 9. stops blood sampling, 10. supplements erythrocyte, and 11. separate displacement blood
Slurry, 12. collect blood plasma, and 13. stop supplementing, and 14. go back red cells transfusion, and 15. collect erythrocyte, and 16. press amount of calculation
Supplementing blood plasma, 17. stoppings are the most defeated.
Detailed description of the invention
Below in conjunction with accompanying drawing, the utility model is described in further detail:
As it is shown in figure 1, this utility model collecting whole blood segregation apparatus includes pipeline 1 and equipment 2.Wherein pipeline
There are blood taking needle 3, connecting tube I 4, connector I 5, anticoagulant for storage of whole blood entrance 6, connecting tube II 7 on 1, separate
Cup 8, connecting tube III 9, plasma bags 10, erythrocyte bag 11, connecting tube IV 12, connector II 13, connecting tube
V 14, connecting tube 6 15；Blood pump 16, centrifuge 17, plasma tube detector 18, pipe is had on equipment 2
Road air detectors 19, blood person's valve 20, red blood cell tube valve 21, blood plasma weigher 22, erythrocyte measures
Scale 23.It is characterized in that: blood taking needle 3 is accessed pipeline 1 by connecting tube I 4 by connector I 5；Blood is protected
Liquid storage entrance 6 is accessed pipeline 1 by connecting tube II 7 by connector I 5；Separate cup 8 is by connecting tube III 9
It is connected with plasma bags 10；Erythrocyte bag 11 is accessed pipeline 1 by connecting tube IV 12 by connector II 13；Even
Fitting I 5 is connected with connector II 13 by connecting tube V 14；Connector II 13 by connecting tube 6 15 with
Separate cup 8 connects；Blood pump 16 is positioned in the connecting tube 6 15 of connector II 13 and separate cup 8；Centrifuge
17 are positioned at separate cup 8 times；Plasma tube detector 18 is positioned at the connecting tube III 9 of separate cup 8 and plasma bags 10
On；Circuit air detector 19 is positioned in the connecting tube 6 15 of blood pump 16 and connector II 13；Blood person's valve
In 20 connecting tubes V 14 being positioned at connector II 13 and connector I 5；Red blood cell tube valve 21 is positioned at connection
In the connecting tube IV 12 of part II 13 and erythrocyte bag 11；Blood plasma weigher 22 is positioned at plasma bags 10 end；Red
Cytolytic dose scale 23 is positioned at erythrocyte bag 11 end.
As in figure 2 it is shown, adopt with arrival before the process that this utility model collecting whole blood separates includes arriving blood sampling volume
Latter two stage of blood volume.Process before wherein arriving blood sampling volume includes the 1st step blood sampling, and the 2nd step separates, the 3rd
Step collects blood plasma, and the 4th step stops taking a blood sample, the 5th step also red cells transfusion, the 6th step collection erythrocyte, and the 7th
Step stops the most defeated, and the 8th step starts blood sampling；The process after blood sampling volume that arrives includes that the 9th step stops blood sampling, the
10 steps supplement erythrocyte, and the 11st step separates displacement blood plasma, and the 12nd step collects blood plasma, and the 13rd step stops supplementing,
14th step also red cells transfusion, the 15th step collects erythrocyte, and the 16th step supplements blood plasma by amount of calculation, and the 17th
Step stops the most defeated.
The method of this utility model collecting whole blood segregation apparatus collection separation whole blood is:
Utilize pipeline 1 and the equipment 2 of device, by the blood taking needle 3 donor source blood donor's vein on pipeline 1
Blood；Gather blood to mix with the anticoagulant for storage of whole blood from anticoagulant for storage of whole blood entrance 6 at pipeline 1 connector I 5
Close anticoagulant；Anticoagulation enters the separate cup 8 of pipeline 1 under the drive of equipment 2 blood pump 16；Separate cup 8 exists
Under the drive of equipment 2 centrifuge 17, anticoagulation is divided into blood plasma and erythrocyte；Blood plasma is from the outlet of separate cup 8
Overflow in plasma bags 10, when equipment 2 plasma tube detector 18 overflows pipeline (connecting tube at blood plasma
III 9), when having monitored erythrocyte in, blood sampling is stopped；Blood pump 16 inverts, by the erythrocyte in separate cup 8
Also it is passed to erythrocyte bag 11, when equipment 2 circuit air detector 19 is going back red cells transfusion pipeline (connecting tube six
15) when monitoring air in, stop the most defeated, enter second circulation blood sampling；And so forth, set when reaching
Determine during blood sampling volume (400mL or 300mL or 200mL), close hull closure 2 blood person's valve 20, stop blood sampling,
Open equipment 2 red blood cell tube valve 21, in separate cup 8, supplement erythrocyte, until equipment 2 plasma tube
Detector 18 finds erythrocyte in blood plasma overflows pipeline (connecting tube III 9)；Stop separate, the most defeated red carefully
Born of the same parents, also transport to red blood cell bag 11 by erythrocyte in separate cup 8；By equipment at the end of erythrocyte supplements
2 weighers 23 measure red blood cell bag in erythrocytic amount, when in separate cup 8, erythrocyte is fed back to 90%
(preferably) after, from blood plasma collecting bag 10 plasma supplemented of the most defeated amount of calculation to erythrocyte bag 11 [according to red
In in cell supplementary end erythrocyte bag 11, erythrocytic amount adds separate cup 8, erythrocytic amount calculates]；Regulate red
In cell bags 11, erythrocyte volume is in prescribed limit, and hematocrit value is in prescribed limit；The the most defeated of blood plasma will
Plasma bags 10 is taken off from equipment 2 blood plasma weigher 22 and blood plasma is returned separate cup 8, more also transports to erythrocyte
Bag 11, it is possible to the connecting tube bottom plasma bags 10 the most also transports to separate cup 8 and erythrocyte bag 11；Return
Also in erythrocyte, the amount of blood plasma is determined by the blood plasma weigher 22 hanging plasma bags 10, it is possible to by blood pump 16 turns
Revolution determine；The Red Blood Cells Concentrate received can directly supply Clinical practice, it is possible to is prepared as red cell suspension；
Prepare red cell suspension to be connected with alserver's solution bag by the perforator of tape splicing sterilizing filter on pipeline
Introduce alserver's solution, it is possible on pipeline, directly connect the alserver's solution bag of dress alserver's solution.
The operation principle of this utility model full-automatic collecting whole blood segregation apparatus is:
After the anticoagulation that blood taking needle 3 gathers enters separate cup 8 by blood pump 16, at separate cup 8 high speed rotating
Under, owing in blood, the proportion of heterogeneity is different, blood being divided into blood plasma and erythrocyte, blood plasma enters blood
Slurry bag 10, erythrocyte enters erythrocyte bag 11；Separation degree and the most defeated situation are by the plasma tube on equipment 2
Detector 18 and circuit air detector 19 monitor；Due to gather the amount of blood need fixing (400mL or
300mL or 200mL), and in donor blood, erythrocytic specific volume is different, follows so using one
Ring carries out gathering to separate and there may be blood plasma and separate not exclusively or blood collection not just stops blood sampling of blood
[plasma tube detector 18 monitoring finds that erythrocyte is automatically stopped to situation；Therefore this programme uses two or more
Circle collection separation blood；The capacity of separate cup 8 is preferably the half collecting Red Blood Cells Concentrate capacity；Front
In the collection circulation in face, the stopping of collection leans on plasma tube detector 18 to overflowing erythrocytic monitoring, finally
The blood sampling overall control that the stopping of one circulation blood sampling is set by equipment 2.Owing to blood is the most acquired enough, and
In separate cup 8, the amount of blood plasma is uncertain, so using erythrocyte to replace, the termination of displacement is also leaned on
Plasma tube detector 18 is to erythrocytic monitoring；Separation terminates, in erythrocyte bag 11 and separate cup 8
The specific volume of Red Blood Cells Concentrate is fixing, determines need according to erythrocytic amount in erythrocyte bag 11 and separate cup 8
Plasma volume to be added adjusts specific volume and the capacity of Red Blood Cells Concentrate, is allowed to meet relevant criterion.Residue blood
Slurry is the fresh plasma prepared.
The above embodiment is interpreted as being merely to illustrate this utility model rather than limiting this utility model
Protection domain.After having read the content of record of the present utility model, technical staff can be to this practicality
Novel make various changes or modifications, these equivalence changes and modify and fall into this utility model claim institute equally
The scope limited.
Claims (6)
1. a full-automatic collecting whole blood segregation apparatus, including single use collecting whole blood separate lines (1)
With full-automatic collecting whole blood separation equipment (2), it is characterised in that: described single use collecting whole blood separates pipe
Blood taking needle (3), connecting tube I (4), connector I (5), anticoagulant for storage of whole blood entrance (6), connecting tube II is had on road (1)
(7), separate cup (8), connecting tube III (9), plasma bags (10), erythrocyte bag (11), connecting tube IV (12), company
Fitting II (13), connecting tube V (14), connecting tube VI (15)；On described full-automatic collecting whole blood separation equipment (2)
Have blood pump (16), centrifuge (17), plasma tube detector (18), circuit air detector (19), blood person's valve (20),
Red blood cell tube valve (21), blood plasma weigher (22), erythrocyte weigher (23)；Wherein said blood taking needle (3) by
Connecting tube I (4) accesses separate lines (1) by connector I (5)；Described anticoagulant for storage of whole blood entrance (6) is by connecting tube
II (7) accesses separate lines (1) by connector I (5)；Separate cup (8) is by connecting tube III (9) and plasma bags (10)
Connect；Described erythrocyte bag (11) is accessed separate lines (1) by connecting tube IV (12) by connector II (13)；Institute
State connector II (13) to be connected with connecting tube V (14).
Full-automatic collecting whole blood segregation apparatus the most according to claim 1, it is characterised in that: described blood
Slurry pipeline detector (18) is positioned in the connecting tube III (9) of separate cup (8) and plasma bags (10).
Full-automatic collecting whole blood segregation apparatus the most according to claim 1 and 2, it is characterised in that: institute
State circuit air detector (19) to be positioned in the connecting tube VI (15) of blood pump (16) and connector II (13).
Full-automatic collecting whole blood segregation apparatus the most according to claim 1 and 2, it is characterised in that: institute
State blood person's valve (20) to be positioned in the connecting tube V (14) of connector II (13) and connector I (5).
Full-automatic collecting whole blood segregation apparatus the most according to claim 1 and 2, it is characterised in that: institute
State red blood cell tube valve (21) to be positioned in the connecting tube IV (12) of connector II (13) and erythrocyte bag (11).
Full-automatic collecting whole blood segregation apparatus the most according to claim 1 and 2, it is characterised in that: institute
Stating blood plasma weigher (22) and be positioned at plasma bags (10) end, described erythrocyte weigher (23) is positioned at erythrocyte bag (11)
End.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620030708.6U CN205460112U (en) | 2016-01-13 | 2016-01-13 | Separator is gathered to full -automatic whole blood |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620030708.6U CN205460112U (en) | 2016-01-13 | 2016-01-13 | Separator is gathered to full -automatic whole blood |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN205460112U true CN205460112U (en) | 2016-08-17 |
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ID=56668386
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201620030708.6U Active CN205460112U (en) | 2016-01-13 | 2016-01-13 | Separator is gathered to full -automatic whole blood |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105498010A (en) * | 2016-01-13 | 2016-04-20 | 重庆三大伟业制药有限公司 | Full-automatic whole blood collection and separation device and method |
| CN110944754A (en) * | 2017-08-18 | 2020-03-31 | 生物安全股份有限公司 | Fluid separation system with pulse dampener |
-
2016
- 2016-01-13 CN CN201620030708.6U patent/CN205460112U/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105498010A (en) * | 2016-01-13 | 2016-04-20 | 重庆三大伟业制药有限公司 | Full-automatic whole blood collection and separation device and method |
| CN105498010B (en) * | 2016-01-13 | 2019-01-11 | 重庆三大伟业制药有限公司 | Full-automatic whole blood collecting and separating device and method |
| CN110944754A (en) * | 2017-08-18 | 2020-03-31 | 生物安全股份有限公司 | Fluid separation system with pulse dampener |
| CN110944754B (en) * | 2017-08-18 | 2022-03-01 | 生物安全股份有限公司 | System for separating biological fluids into their components and uses thereof |
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Legal Events
| Date | Code | Title | Description |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CP03 | Change of name, title or address | ||
| CP03 | Change of name, title or address |
Address after: 402460 No. 21, east section of Changzhou Avenue, Changzhou street, Rongchang District, Chongqing Patentee after: Haier Blood Technology Chongqing Co.,Ltd. Address before: 402460 Banqiao Industrial Park, Rongchang County, Chongqing Patentee before: CHONGQING SANDA WEIYE PHARMACEUTICAL Co.,Ltd. |