CN208626683U - A kind of platelet rich plasma extraction element - Google Patents

A kind of platelet rich plasma extraction element Download PDF

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Publication number
CN208626683U
CN208626683U CN201820812179.4U CN201820812179U CN208626683U CN 208626683 U CN208626683 U CN 208626683U CN 201820812179 U CN201820812179 U CN 201820812179U CN 208626683 U CN208626683 U CN 208626683U
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transparent
liquid
rich plasma
platelet rich
piston
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赖文
孙传伟
卞徽宁
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Abstract

The utility model discloses a kind of platelet rich plasma extraction elements, including transparent piston type dispenser, transparent conduit and transparent liquid waste collector;One end of the transparent conduit connects the outlet end of the transparent piston type dispenser, and the other end of the transparent conduit is free end, and the free end extends to inside the transparent liquid waste collector through the liquid feeding end of the transparent liquid waste collector;Also, the tube wall of the free end and the liquid feeding end are tightly connected.By the technical program, simple structure, preparation convenience, liquid separation accurately technical purpose can achieve.

Description

A kind of platelet rich plasma extraction element
Technical field
The utility model relates to medical instruments field more particularly to a kind of platelet rich plasma extraction elements.
Background technique
Platelet rich plasma (Platelet Rich Plasma, abbreviation PRP) is as obtained from centrifugal blood containing height The blood plasma of concentration blood platelet.PRP has the function of stopping blooding rapidly, relieve pain, accelerating wound healing, can the postoperative scar of high degree mitigation The formation of trace.In addition, after extracted enrichment processing, can be used for related disease since PRP can be extracted from patient's self-blood Treatment, thus abundance, materials are convenient, and preparation method is simple and body can be allowed to absorb.Itself PRP use is avoided that The problem of viral transmission and immunological rejection, occurs.Therefore PRP is widely used in various surgical operations, bone surgery and shaping Operation, in terms of being also widely used in medical cosmetology at present, so the extraction quality of PRP be the key that influence its function and effect because Element.
Currently, the method for generally yielding platelet rich plasma be by being extracted respectively again after being centrifuged to blood, for up to To this purpose, there are some technical research in correlative technology field.Such as Chinese utility model patent 201720130126.X is disclosed A kind of platelet rich plasma centrifuge tube from top to bottom successively includes serum area, platelet rich plasma area, leucocyte area, red thin Born of the same parents area is connected between platelet rich plasma area and leucocyte area by upper through-hole, under passing through between leucocyte area and red blood cell area The side wall of through-hole connection, leucocyte area is equipped with drawing holes, corresponds to the upper through-hole, lower through-hole, drawing holes, the leucocyte area It is switched equipped with a threeway T-type, makes through-hole, lower through-hole, drawing holes realize conducting or closed state as needed in this way, make The extraction of platelet rich plasma centrifuge tube is simpler, is also not easy to be contaminated blood plasma.
But the device need using head protection cover etc. devices protected, structure is complex, be not easy to installation and It utilizes;Moreover, the device is also unable to reach the technical requirements of accurate liquid separation.
Utility model content
For overcome the deficiencies in the prior art, the technical purpose that the utility model is realized be to provide a kind of structure it is simple, Prepare easy for installation, liquid separation accurately platelet rich plasma extraction element.
To reach above-mentioned technical purpose, technical solution content used by the utility model is specific as follows:
A kind of platelet rich plasma extraction element, including transparent piston type dispenser, transparent conduit and transparent waste collection Device;One end of the transparent conduit connects the outlet end of the transparent piston type dispenser, and the other end of the transparent conduit is Free end, the free end extend to inside the transparent liquid waste collector through the liquid feeding end of the transparent liquid waste collector;And And the tube wall of the free end and the liquid feeding end are tightly connected.
It is complex to solve structure in the prior art, it is not easy to install and utilize, and be unable to reach accurate liquid separation Technological deficiency, inventor are innovatively connected to the transparent piston type dispenser and described using transparent conduit in this application Bright liquid waste collector, and the transparent conduit extends in the transparent liquid waste collector.Compared to the prior art directly Piston type dispenser is connected to by a communication means and liquid waste collector, the application extend to conduit in transparent liquid waste collector And conduit is set as transparent, cooperates transparent liquid waste collector, can be accurate through the color of liquid in observation transparent conduit Ground pushes the stratified liquid after centrifugation, realizes that the liquid in different layers area precisely separates.And set transparent for piston dispenser , when pushing the liquid after centrifugation, the laminated fluid level of centrifugal liquid can also be observed, cooperates transparent conduit, it can be further The precision that difference once goes liquid to separate is improved, the waste of platelet rich plasma is reduced, improves and extracts having for platelet rich plasma Efficiency.
As the first improvement of the utility model platelet rich plasma extraction element, the diameter value of the transparent conduit Range is 1~5mm.
The diameter value range of the more preferable transparent conduit is 1~3mm.
Those skilled in the art lead to influence separation accuracy it is contemplated that flow rate of liquid is excessive, and flow velocity is too small then It is easy to cause liquid that can not flow.So present inventor proves by multiple creative experiments, transparent led described The diameter range of pipe is arranged between 1~5mm, preferably coutroi velocity, raising liquid can separate accuracy.
As second of improvement of the utility model platelet rich plasma extraction element, the radius of the free end is along transparent The liquid feeding end of liquid waste collector is gradually reduced to the direction for freely bringing out liquid portion.
The conduit constant compared to radius, the transparent conduit that radius gradually decreases can preferably control the stream of liquid in pipe Speed flows into transparent waste collection so as to be accurately controlled liquid, reaches the technical purpose of accurate liquid separation.
Preferably, the liquid portion that goes out of the free end is in straight peen elbow or hook-type or U-shaped, can prevent transparent liquid waste collector Interior liquid is flow backwards, and improves the quality of liquid extraction.
Preferably, the transparent piston type dispenser includes cylinder and piston rod;The outlet end is arranged in the cylinder One end, the piston rod is slidably connected the other end of the cylinder.
It is highly preferred that the piston rod includes piston crown and push rod;The pusher body connects the piston crown.
Further, the push rod is detachably connected the back side of the piston crown.Preferably, the side of being detachably connected Formula is clamping or is threadedly coupled.By using clamping or the mode being threadedly coupled, the fixation between push rod and piston crown is realized Connection, such operator, which only needs to push directly on push rod, can control piston head in the internal slide of cylinder, push away to realize The purpose of liquor charging body.Moreover, dividing in this way when push rod and piston crown are attached by clamping or thread connecting mode Centrifugally operated before liquid, user can also separate push rod from piston crown, so that piston type dispenser be facilitated to be mounted on It is centrifuged on centrifuge.
Alternatively, the push rod includes the body of rod and set lid;Described body of rod one end is fixedly connected with the back side of the piston crown On, the other end is fixed on the set lid;The set lid is socketed the outer wall of the cylinder and connect with the cylinder screw.
It is connected through a screw thread, so that the piston rod forms rotary-piston, operator can make institute by rotating push rod It states piston rod and realizes back-and-forth motion in a rotative pattern in transparent piston type dispenser, to realize the purpose of the push of liquid.
Inventor is some it was found that, according to being connected through a screw thread, so that the piston rod forms rotary-piston The structure being threadingly advanced is formed, the shadow that piston slightly moves caused interference experiment result can be reduced during centrifugation It rings.If piston generates movement in centrifugal process, the concentration of blood platelet may be had some impact on.The results show, without dry Blood platelet can be concentrated 5~11 times when disturbing, and having interference is that blood platelet is only concentrated 2~3 times, and piston rod is arranged to rotary-piston The mobile interference to experiment of piston can be substantially reduced, so that centrifugation and separating resulting are be more good.
Preferably, the transparent conduit is between the transparent piston type dispenser and the transparent liquid waste collector Part is additionally provided with communicating valve.
It should be noted that the communicating valve can control whether liquid is received in transparent piston type dispenser and transparent waste liquid It is moved between storage, the leakproofness of described device can also be increased, avoid depositing causes sample to pollute in operation, further Improve the stability and safety in platelet rich plasma extraction process.
Preferably, it is additionally provided with ventilated membrane on the transparent liquid waste collector, is mainly used for equilibrium air pressure, prevents piston from retreating When generate air.
Compared with prior art, the utility model has the beneficial effects that:
1, the platelet rich plasma extraction element of the utility model is connected to the transparent piston type liquid separation by transparent conduit Device and the transparent liquid waste collector, and the transparent conduit extends in the transparent liquid waste collector, compared to existing There is technology directly to pass through a communication means and be connected to transparent piston type dispenser and transparent liquid waste collector, the present apparatus is by transparent conduit It extends in transparent liquid waste collector, can accurately push liquid, realize the accurate separation of the liquid in different layers area;
2, the platelet rich plasma extraction element of the utility model preferably exists the diameter range setting of the transparent conduit Between 1~5mm, can preferably coutroi velocity, while liquid separation accuracy can be improved;
3, the radius of the platelet rich plasma extraction element of the utility model, free end is saturating along the radius edge of the free end The liquid feeding end of bright liquid waste collector is gradually reduced to the direction for freely bringing out liquid portion, the conduit constant compared to radius, this is practical Novel transparent conduit can preferably control the flow velocity of liquid in pipe, receive to more be accurately controlled liquid and flow into transparent waste liquid Storage further reaches the technical purpose of accurate liquid separation;
4, the liquid portion that goes out of the free end of transparent conduit is set hook by the platelet rich plasma extraction element of the utility model Shape or U-shaped can prevent the liquid in transparent liquid waste collector from flowing backwards, and prevent the quality for influencing liquid extraction;
The above description is merely an outline of the technical solution of the present invention, in order to better understand the skill of the utility model Art means, and being implemented in accordance with the contents of the specification, and in order to allow the above and other purpose, feature of the utility model It can be more clearly understood with advantage, it is special below to lift preferred embodiment, and cooperate attached drawing, detailed description are as follows.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the platelet rich plasma extraction element more preferably embodiment of the utility model;
Fig. 2 is the structural schematic diagram of another more preferably embodiment of platelet rich plasma extraction element of the utility model;
Fig. 3 is the structural schematic diagram of the more preferably embodiment of the utility model transparent conduit;
Fig. 4 is the section knot of another more preferably embodiment of the platelet rich plasma extraction element push rod of the utility model Structure schematic diagram;
Fig. 5 is the cross-section structure signal of the another more preferably embodiment of platelet rich plasma extraction element of the utility model Figure;
Wherein, each appended drawing reference are as follows: 1, transparent piston type dispenser;2, transparent liquid waste collector;3, transparent conduit;11, Piston crown;4, push rod;41, the body of rod;42, lid is covered;5, communicating valve;6, liquid injection port.
Specific embodiment
Further to illustrate that the utility model is the technical means and efficacy reaching predetermined purpose of utility model and being taken, Below in conjunction with attached drawing and preferred embodiment, to foundation specific embodiment of the present utility model, structure, feature and its effect, in detail Carefully it is described as follows:
Embodiment 1
As shown in Figure 1, the utility model platelet rich plasma extraction element includes transparent piston type dispenser 1, transparent leads Pipe 3 and transparent liquid waste collector 2;One end of the transparent conduit connects the outlet end of the transparent piston type dispenser, described The other end of transparent conduit is free end, and the free end extends to described transparent through the liquid feeding end of the transparent liquid waste collector Inside liquid waste collector;Also, the tube wall of the free end and the liquid feeding end are tightly connected.It is the base of the utility model above Plinth embodiment.
In conjunction with above embodiment, the transparent piston type dispenser includes cylinder and piston rod;The outlet end setting In one end of the cylinder, the piston rod is slidably connected the other end of the cylinder.
In a more specific embodiment, as shown in Figure 1, the piston rod includes piston crown 11 and push rod 4;It is described to push away The body of rod connects the piston crown.
The operating process of the present apparatus is as follows: transparent piston type dispenser now being taken apart addition blood sample, and will be saturating Open piston formula dispenser, which is put into separation, the liquid of the transparent piston type dispenser of first time separating resulting inside centrifuge, can be divided into three Layer: being successively platelet poor plasma, platelet rich plasma and red blood cell.Then transparent piston type liquid separation is connected by device design Device, transparent conduit and transparent liquid waste collector, (liquid is not shown) as shown in Figure 1.Operator can push push rod, so that being located at The red blood cell on transparent piston type dispenser top is entered in the transparent liquid waste collector by conduit, (liquid as shown in Figure 2 It is not shown).To red blood cell layer completely into transparent liquid waste collector, pull push rod that remaining two layers of liquid is returned again Into transparent piston type dispenser and transparent piston type dispenser is dismantled and carries out second of centrifugal movement.The result of secondary separation Be: what it is by near-transparent piston type dispenser top is platelet poor plasma, and what it is by near-transparent piston type dispenser bottom end is rich blood Platelet-poor plasma.Again extraction element is installed by above-mentioned requirements, pushes push rod that platelet poor plasma is received into transparent waste liquid Storage, pulls push rod that platelet rich plasma is emptied back into transparent piston type dispenser after entering completely, that is, realizes rich The extraction of thrombocyte plasma.
In the technical scheme, complex to solve structure in the prior art, it is not easy to install and utilize, and can not Reach the technological deficiency of accurate liquid separation, inventor is innovatively connected to the transparent piston type by transparent conduit in this application Dispenser and the transparent liquid waste collector, and the transparent conduit extends in the transparent liquid waste collector.It compares Directly pass through communication means connection piston type dispenser in the prior art and liquid waste collector, the application extend to conduit In bright liquid waste collector and conduit is set as transparent, cooperates transparent liquid waste collector, through liquid in observation transparent conduit Color, can accurately push centrifugation after stratified liquid, realize different layers area liquid precisely separate.And piston is divided Liquid device is set as transparent, when pushing the liquid after centrifugation, can also observe the laminated fluid level of centrifugal liquid, cooperate transparent lead Pipe can be further improved the different precisions for once going liquid to separate, reduce the waste of platelet rich plasma, improves and extracts rich blood The effective percentage of platelet-poor plasma.
Embodiment 2
The present embodiment is a kind of preferred embodiment on the basis of above-described embodiment 1.The present embodiment 2 with it is upper The difference for stating embodiment 1 is: in the present embodiment, the diameter value range of the transparent conduit is 1~5mm.
It should be noted that it is preferred that being arranged the diameter range of the transparent conduit between 1~5mm, it can be preferably Coutroi velocity can preferably control liquid movement, can also reduce the time required for PRP is separated, improve separative efficiency.
In another more preferably embodiment, the diameter value range of the transparent conduit is 1~3mm.
To understand flow condition in different tube diameters, inventor has made following test: with diameter for 1mm-5mm, capacity is The pipeline of 60ml is tested, and pushes push rod with identical dynamics (1kg), and the liquid for being maintained to flow through different pore size pipeline forms water Drop-wise the time required to calculating, while counting flow rate of liquid.The experimental results are shown inthe following table:
Pipe diameter (mm) Capacity (ml) Time (s) Flow rate of liquid (ml/s)
1 60 44.02 1.36
2 60 7.39 8.12
3 60 4.49 13.36
4 60 2.41 24.89
5 60 2.14 28.03
By above-mentioned experimental result it is found that in the first aspect, when pipe diameter is between 1~5mm, flow velocity can be Within 30ml/s, and flow velocity will not too low (be more than or equal to 1.36ml/s) so that separative efficiency meets the requirements and accuracy is higher.
In the second aspect, when pipe diameter is greater than 3mm, flow rate of liquid can be increased over 20ml/s and reach more Stable state, it is seen that when being greater than 3mm, flow control effect can be reduced, therefore be more preferably in the diameter range of 1~3mm Selection.
And in another embodiment, the radius of the free end is along the liquid feeding end of transparent liquid waste collector to freely bringing out The direction in liquid portion is gradually reduced.The transparent conduit of the conduit constant compared to radius, the utility model can preferably control pipe The flow velocity of interior liquid further reaches the skill of accurate liquid separation so that being more accurately controlled liquid flows into transparent waste collection Art purpose.
As the further improvement of above two embodiment, as shown in figure 3, the liquid portion that goes out of the free end is in hook-type. The conduit being located in collector tube is gone out into liquid portion and is arranged to hook formation, can prevent the liquid in collector tube from flowing backwards, prevent from influencing The quality of liquid extraction.And in other embodiments, the liquid portion out can also be arranged to U-shaped.
In conjunction with above embodiment, in another preferred embodiment, the liquid portion out is equipped with angular cut.It will be by position Go out liquid portion in the conduit in collector tube and be arranged to angular cut, can be convenient liquid in pipe and flow into collector tube.
Remaining embodiment and corresponding technical effect of the present embodiment are identical as remaining embodiment, and details are not described herein.
Embodiment 3
The present embodiment is the further preferred embodiment in above-described embodiment 1 to transparent conduit, and the present embodiment can be with Embodiment in embodiment 2 combines or individually implements.
In a kind of preferred embodiment, the tube wall of the transparent conduit is equipped with graduation mark.It transparent is led described The tube wall of pipe is equipped with graduation mark, has both sides beneficial effect.On the one hand remaining liq in transparent conduit can be measured Volume, to facilitate subsequent collection to calculate, so that acquisition measurement is more accurate;It on the other hand can be by the cross of graduation mark Line, observes the layering of different colours liquid, and operator can compare the stratification line of liquid, preferably control by the horizontal line The propulsion or stopping of liquid more make fluid flow more accurately to control the flow that liquid enters transparent liquid waste collector It is controlled, further reaches the technical requirements of accurate liquid separation.
In a kind of preferred embodiment, the quantity for going out liquid portion of the free end is one or more, to control Controlling flow enters the flow velocity of transparent liquid waste collector, improves the rate and efficiency of extracting liq.More specifically, liquid portion is one out In the case where, the as through-hole of end of conduit.It in other embodiments, can be by conduit in the case that liquid portion is multiple out End be arranged to parted hair form it is multiple go out fluid through-holes.
Remaining embodiment and corresponding technical effect of the present embodiment are identical as remaining embodiment, and details are not described herein.
Embodiment 4
The present embodiment is the further preferred embodiment in above-described embodiment 1 to other component structure and connection relationship, The present embodiment can be implemented in conjunction with the embodiment in embodiment 2 and 3 or individually.
In conjunction with above embodiment, as a preferred embodiment, the push rod is detachably connected the piston head The back side in portion.
In conjunction with above embodiment, in a kind of preferred embodiment, as shown in the sectional view of Fig. 4, the push rod Including the body of rod 41 and set lid 42;Described body of rod one end is fixedly connected on the back side of the piston crown 11, and the other end is fixed on The set lid;The set lid is socketed the outer wall of the cylinder and connect with the cylinder screw, so that the piston is formed Rotary-piston.The piston forms rotary-piston, and operator can make the piston in transparent piston type by rotating push rod The purpose that liquid promotes is realized in sealing movement in dispenser.In addition, using being connected through a screw thread, so that the piston rod is formed Rotary-piston forms the structure being threadingly advanced, and piston can be reduced during centrifugation and slightly moves caused interference experiment As a result influence.If piston generates movement in centrifugal process, the concentration of blood platelet may be had some impact on.Experimental result card Bright, blood platelet can be concentrated 5~11 times when noiseless, and having interference is that blood platelet is only concentrated 2~3 times, and piston rod is arranged to Rotary-piston can substantially reduce the mobile interference to experiment of piston, so that centrifugation and separating resulting are be more good.
In another preferred embodiment of the utility model, as shown in the sectional view of Fig. 5, the transparent conduit 3 Part between the transparent piston type dispenser 1 and the transparent liquid waste collector 2 is additionally provided with communicating valve 5.The connection Valve can control whether liquid moves between transparent piston type dispenser and transparent liquid waste collector, can also increase the dress The leakproofness set, avoid depositing causes sample to pollute in operation, further improves in platelet rich plasma extraction process Stability and safety.
In another preferred embodiment of the utility model, as shown in figure 5, on the transparent piston type dispenser also Equipped with liquid injection port 6, convenient injection or tapping into the transparent piston type dispenser.
In another preferred embodiment of the utility model, as shown in figure 5, the transparent piston type dispenser top Tapered structure, flow rate of liquid in more convenient control dispenser.
In another preferred embodiment of the utility model, the transparent liquid waste collector is equipped with ventilated membrane.Institute It states ventilated membrane and is mainly used for equilibrium air pressure, air is generated when preventing piston from retreating.It should be noted that saturating in the utility model Air film is the membrane body of a gas-permeable, liquid-impermeable.
In the yet another preferred form of the utility model, set on the cylinder body outer wall of the transparent piston type dispenser There is graduation mark.By this graduation mark, operator can understand the volume of measurement stratified liquid, calculate the volume for pushing liquid, with And the last volume for retaining platelet rich plasma, the volume of the platelet rich plasma more accurately finally extracted, to reach To the technical requirements of accurate liquid separation.
Moreover, the maximum length of the push rod may be arranged as barrel lenght and required platelet rich plasma height it Difference, in this way after secondary centrifuging, when push rod to be pushed to the extreme position of its length, obtained platelet rich plasma volume The requirement of preset vol numerical value can be met at once, it is more convenient to use.
Remaining embodiment and corresponding technical effect of the present embodiment are identical as remaining embodiment, and details are not described herein.
Above embodiment is only preferred embodiments of the present invention, cannot be protected with this to limit the utility model Range, the variation of any unsubstantiality that those skilled in the art is done on the basis of the utility model and replacement belong to In the utility model range claimed.

Claims (9)

1. a kind of platelet rich plasma extraction element, it is characterised in that: including transparent piston type dispenser, transparent conduit and transparent Liquid waste collector;One end of the transparent conduit connects the outlet end of the transparent piston type dispenser, the transparent conduit The other end is free end, and the free end extends to the transparent liquid waste collector through the liquid feeding end of the transparent liquid waste collector It is internal;Also, the tube wall of the free end and the liquid feeding end are tightly connected;The radius of the free end is along transparent waste collection The liquid feeding end of device is gradually reduced to the direction for freely bringing out liquid portion.
2. platelet rich plasma extraction element as described in claim 1, which is characterized in that the diameter value of the transparent conduit Range is 1~5mm.
3. platelet rich plasma extraction element as described in claim 1, which is characterized in that the free end goes out liquid portion in straight Head elbow or hook-type or U-shaped.
4. platelet rich plasma extraction element as described in claim 1, which is characterized in that the transparent piston type dispenser packet Include cylinder and piston rod;The outlet end is arranged in one end of the cylinder, and the piston rod is slidably connected the another of the cylinder One end.
5. platelet rich plasma extraction element as claimed in claim 4, it is characterised in that: the piston rod includes piston crown And push rod;The push rod connects the piston crown.
6. platelet rich plasma extraction element as claimed in claim 5, it is characterised in that: the push rod is detachably connected described The back side of piston crown.
7. platelet rich plasma extraction element as claimed in claim 5, it is characterised in that: the push rod includes the body of rod and upper shield Body;Described body of rod one end is fixedly connected on the back side of the piston crown, and the other end is fixed on the set lid;The set lid It is socketed the outer wall of the cylinder and is connect with the cylinder screw.
8. the platelet rich plasma extraction element as described in claim 1-7 any one, which is characterized in that the transparent conduit Part between the transparent piston type dispenser and the transparent liquid waste collector is additionally provided with communicating valve.
9. the platelet rich plasma extraction element as described in claim 1-7 any one, it is characterised in that: the transparent waste liquid Collector is equipped with ventilated membrane.
CN201820812179.4U 2018-05-29 2018-05-29 A kind of platelet rich plasma extraction element Active CN208626683U (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108392855A (en) * 2018-05-29 2018-08-14 孙传伟 A kind of platelet rich plasma extraction element
WO2022077320A1 (en) * 2020-10-15 2022-04-21 Kartigen Biomedical Inc. Kit for isolation of platelet-rich plasma and the method using the same

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108392855A (en) * 2018-05-29 2018-08-14 孙传伟 A kind of platelet rich plasma extraction element
WO2022077320A1 (en) * 2020-10-15 2022-04-21 Kartigen Biomedical Inc. Kit for isolation of platelet-rich plasma and the method using the same

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