CN108760455A - A kind of filter device of blood - Google Patents
A kind of filter device of blood Download PDFInfo
- Publication number
- CN108760455A CN108760455A CN201810600680.9A CN201810600680A CN108760455A CN 108760455 A CN108760455 A CN 108760455A CN 201810600680 A CN201810600680 A CN 201810600680A CN 108760455 A CN108760455 A CN 108760455A
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- sealing
- blood
- plug
- filter device
- pipette
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/34—Purifying; Cleaning
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The invention belongs to blood collection technical fields, disclose a kind of filter device of blood.The filter device, including sealing cover, sealing-plug and tube body, sealing-plug can be stretched into hermetically and be equipped in the test tube of blood, and sealing-plug is internally provided with the pipette for draw blood.One end of tube body is connected to sealing-plug, and the other end is connected to sealing cover, and filter membrane is provided between sealing-plug and tube body, and tubular body is provided with liquid storage cylinder and connecting tube, and one end of connecting tube is communicated in pipette, and the other end is set on the inner wall of liquid storage cylinder.Filter device personnel easy to operation quick and precisely filtering blood, reduces the incidence of haemolysis.Meanwhile it overcoming the prior art and existing using more, the complicated for operation defect of tool, simple in structure, simple operation.In addition, avoiding the case where being susceptible to pollution in the prior art.
Description
Technical field
The present invention relates to blood collection technical field more particularly to a kind of filter devices of blood.
Background technology
Medical institutions are generally by the blood at the positions such as vein, artery or the finger of acquisition human body to obtain blood mark
This.
In general, blood preparation includes whole blood and blood plasma, wherein by whole blood using the side of natural subsidence after being mixed with anti-coagulants
Formula carries out blood filtration using centrifugal mode so that and whole blood is layered, and the flaxen liquid in upper layer is blood plasma, under
The red opaque red blood cell of layer depth, intermediate one layer is opaque leucocyte and blood platelet.But using the side of natural subsidence
The time of formula, filtering is longer, and is unable to high-throughput isolation whole blood and obtains blood plasma；Using centrifugal mode, centrifuging
Process red blood cell can inevitably rupture, and hemoglobin is caused to escape, that is, red blood cell dissolving, abbreviation haemolysis.Separately
Outside, the prior art needs multiple steps such as to pass through injection, centrifugation and extract in filtering, and operation is sufficiently complex, and easily causes
Pollution.
Invention content
The purpose of the present invention is to provide a kind of filter device of blood, personnel easy to operation quick and precisely filtering blood,
Reduce the incidence of haemolysis.
For this purpose, the present invention uses following technical scheme：
A kind of filter device of blood, including：Sealing cover；Sealing-plug, the sealing-plug can be stretched into hermetically and be equipped with
In the test tube of blood, the sealing-plug is internally provided with the pipette for draw blood；Tube body, one end connection of the tube body
In the sealing-plug, the other end is connected to the sealing cover, and filter membrane, the pipe are provided between the sealing-plug and the tube body
Body is internally provided with liquid storage cylinder and connecting tube, and one end of the connecting tube is communicated in the pipette, and the other end is set to described
In liquid storage cylinder.
Preferably, the bottom of the sealing-plug is provided with the imbibition partition board for being communicated in the pipette.
Preferably, the imbibition partition board is conical structure, and bigbore one end of the imbibition partition board is far from institute
State pipette setting.
Preferably, the section distributing damper being provided at the top of the sealing-plug below the filter membrane, described section
Face distributing damper is concave structure and is recessed to the direction far from the filter membrane that the section distributing damper is respectively communicated in described
Pipette and the connecting tube.
Preferably, the outlet end of the pipette is set to the center of the section distributing damper, the section
The circumferential direction of pipette described in distributing damper upper edge is evenly arranged with several blades.
Preferably, the shape of the blade is helical structure.
Preferably, the input end of the connecting tube is set to the marginal position of the section distributing damper.
Preferably, the outer wall of the tube body is provided with buckle, the bottom surface of the buckle can press on the test tube
End face.
Preferably, the outer wall of the sealing cover is provided with several non-skid threads.
Preferably, the inner wall of the sealing cover is provided with sealing ring.
Beneficial effects of the present invention：
1) it is connected to sealing-plug by the way that one end of tube body is arranged, the other end is connected to sealing cover, between sealing-plug and tube body
It is provided with filter membrane, when in use, sealing cover, tube body and sealing-plug are integrally pushed so that sealing-plug can hermetically stretch into appearance
It is equipped in the test tube of blood, blood enters after the pipette inside sealing-plug, and goes out red blood cell etc. by membrane filtration and divide greatly
Sub- substance forms blood plasma.The prior art compare by the way of natural subsidence, personnel easy to operation quick and precisely filtering blood,
The time of filtering is short, and high-throughput isolation whole blood and obtain blood plasma.
2) liquid storage cylinder and connecting tube are provided with by tubular body, one end of connecting tube is communicated in pipette, and the other end is set
It is placed in liquid storage cylinder so that blood plasma is entered by connecting tube in the liquid storage cylinder of tube body, when blood plasma needs shift experiment, is opened close
Capping can be drawn blood plasma using liquid-transfering gun or suction pipe, transfer；When blood plasma needs storage, by sealing cover, tube body, sealing
Plug and test tube store as a whole, avoid the case where being susceptible to pollution in the prior art.
3) be equipped in the test tube of blood since sealing-plug can be stretched into hermetically, under the influence of air pressure, sealing-plug without
It needs and contacting blood, blood can be pressed into pipette, avoid being pressed onto red blood cell and leading to red blood cell rupture, be adopted with the prior art
It is compared with centrifugal mode, reduces the incidence of haemolysis.
4) filter device of the invention overcomes the prior art and exists using more, the complicated for operation defect of tool, structure letter
It is single, simple operation.
Description of the drawings
Fig. 1 is the filter device vertical view of blood of the present invention；
Fig. 2 is Fig. 1 a form of sectional views at A-A；
Fig. 3 be blood of the present invention filter device in a form of sealing-plug structural schematic diagram；
Fig. 4 is the vertical view of the filter device middle section distributing damper of blood of the present invention；
Fig. 5 is Fig. 1 another form of sectional views at A-A；
Fig. 6 be blood of the present invention filter device in another form of sealing-plug structural schematic diagram；
Fig. 7 is the structural schematic diagram of the filter device middle tube body of blood of the present invention；
Fig. 8 be blood of the present invention filter device in sealing cover structural schematic diagram.
In figure：
1, sealing-plug；2, tube body；3, sealing cover；4, test tube；
11, pipette；12, imbibition partition board；13, section distributing damper；14, blade；
21, filter membrane；22, liquid storage cylinder；23, connecting tube；24, it buckles；
31, non-skid thread；32, sealing ring.
Specific implementation mode
Technical solution to further illustrate the present invention below with reference to the accompanying drawings and specific embodiments.
A kind of filter device of blood is present embodiments provided, as shown in Figs. 1-2, which includes sealing cover 3, close
Blocking 1 and tube body 2, sealing-plug 1 can be stretched into hermetically and be equipped in the test tube 4 of blood, and sealing-plug 1 is internally provided with for inhaling
Take the pipette 11 of blood.Meanwhile one end of tube body 2 is connected to sealing-plug 1, the other end is connected to sealing cover 3,1 He of sealing-plug
Filter membrane 21 is provided between tube body 2, tube body 2 is internally provided with liquid storage cylinder 22 and connecting tube 23, and one end of connecting tube 23 is communicated in
Pipette 11, the other end are set in liquid storage cylinder 22.
One end by the way that tube body 2 is arranged is connected to sealing-plug 1, and the other end is connected to sealing cover 3, sealing-plug 1 and tube body 2 it
Between be provided with filter membrane 21, when in use, push sealing cover 3, tube body 2 and sealing-plug 1 are whole so that sealing-plug 1 can seal
Ground, which stretches into, to be equipped in the test tube 4 of blood, and blood enters after the pipette 11 inside sealing-plug 1, and filtered by filter membrane 21
Go out the macromolecular substances such as red blood cell and forms blood plasma.The prior art compare by the way of natural subsidence, personnel easy to operation are fast
The accurate filtering blood of speed, the time of filtering is short, and high-throughput isolation whole blood and obtain blood plasma.
By being internally provided with liquid storage cylinder 22 and connecting tube 23 in tube body 2, one end of connecting tube 23 is communicated in pipette 11,
The other end is set on the inner wall of liquid storage cylinder 22 so that blood plasma is entered by connecting tube 23 in the liquid storage cylinder 22 of tube body, and blood plasma is worked as
When needing shift experiment, sealing cover 3 is opened, blood plasma can be drawn using liquid-transfering gun or suction pipe, transfer；When blood plasma needs to store
When, sealing cover 3, tube body 2, sealing-plug 1 and test tube 4 will be stored as a whole, and avoid blood plasma in the prior art and be susceptible to
The case where pollution.
It is equipped in the test tube 4 of blood since sealing-plug 1 can be stretched into hermetically, under the influence of air pressure, 1 nothing of sealing-plug
It needs and contacting blood, blood can be pressed into pipette 11, avoid being pressed onto red blood cell and leading to red blood cell rupture, with the prior art
It is compared using centrifugal mode, reduces the incidence of haemolysis.
The filter device of the present invention overcomes the prior art and there is more, the complicated for operation defect of the tool of using, simple in structure,
Simple operation.
As Figure 2-3, the bottom of sealing-plug 1 is provided with the imbibition partition board 12 for being communicated in pipette 11.Wherein imbibition every
Plate 12 is conical structure, and bigbore one end of imbibition partition board 12 is arranged far from pipette 11.Due to the imbibition of cone
Partition board 12 has the function of gathering, and blood can be pushed to travel forward subsequently into pipette 11, while imbibition partition board 12 is also
Can by the red blood cell of part in blood or macromolecular components with blood plasma is a degree of is isolated, play what auxiliary tentatively filtered
Effect.
As in Figure 2-4, the top of sealing-plug 1 is provided with the section distributing damper 13 positioned at 21 lower section of filter membrane, section point
Baffle 13 is flowed to be concave structure and to the direction far from filter membrane 21 be recessed.Due to the concave structure of section distributing damper 13, compare
Compared with planar structure, the section of the circulation of blood is increased, is conducive to high-throughput isolation blood and obtains blood plasma.Meanwhile by cutting
Face distributing damper 13 is recessed to the direction far from filter membrane 21, avoids section distributing damper 13 and is directly in contact with filter membrane 21, increases
Add the space between section distributing damper 13 and filter membrane 21, reduces filter pressure, and then improve filter effect.
Wherein, it is exactly the outlet end of pipette 11 on the center of above-mentioned section distributing damper 13, is shunted in section
The circumferential direction of 13 upper edge pipette 11 of baffle is evenly arranged with several blades 14, and the input end of connecting tube 23 is set to section point
Flow the marginal position of baffle 13.Since the outlet end of pipette 11 is set to the center of section distributing damper 13, connecting tube
23 input end is set to the marginal position of section distributing damper 13 so that section distributing damper 13 is respectively communicated in pipette 11
With connecting tube 23.Therefore, the blood in pipette 11 is dispersed to the margin location of section distributing damper 13 by the guiding of blade 14
It sets, and then can flow into connecting tube 23.
It is circumferentially disposed on section distributing damper 13 along pipette 11 by blade 14, the guiding to blood is realized, is had
Conducive to the flow velocity of reduction blood, and then the macromolecular components such as red blood cell are effectively filtered conducive to filter membrane 21.In order to further increase
Blade 14 can be shaped to helical structure or arc structure by filter effect, increase connecing for blade 14 and blood
Contacting surface is accumulated, and then further decreases velocity of blood flow, achievees the purpose that best filter effect.
It should be strongly noted that the present embodiment pair cross-section distributing damper 13 is in the position of sealing-plug 1 and is not construed as limiting, such as
Shown in Fig. 5-6, the top of sealing-plug 1 is provided with above-mentioned section distributing damper 13, and blood is set to through being directed into for blade 14
The pipette 11 of the center of sealing-plug 1, after filter membrane 21 effectively filters the macromolecular components such as red blood cell, into being set to
In the connecting tube 23 of 1 marginal position of sealing-plug.Wherein the outlet end of connecting tube 23 can be bevel-faced form, can be from convenient for blood
Connecting tube 23 enters in liquid storage cylinder 22.
As shown in Fig. 2,5, the threaded one end of tube body 2 is connected to sealing-plug 1, and the other end is threadedly connected to sealing cover 3, when need
It wants in use, be conveniently connected to each other, assemble, and not easy to fall off；When not needing in use, tube body 2, sealing cover 3 and sealing-plug 1
Storage space is saved in individually storage.Its middle tube body 2 is internally provided with liquid storage cylinder 22 and connecting tube 23, and one end of connecting tube 23 is logical
It crosses section distributing damper 13 and is communicated in pipette 11, the other end is obliquely installed on the inner wall of liquid storage cylinder 22 so that blood plasma passes through
Connecting tube 23 enters in the liquid storage cylinder 22 of tube body 2, and wherein liquid storage cylinder 22 and connecting tube 23 is an integral molding structure.Due to tube body 2
Filter membrane 21 is provided between sealing-plug 1, the blood plasma completed through filtering is directly entered by connecting tube 23 inside tube body 2 so that
Plasma sample is isolated from the outside, and avoids the case where being susceptible to pollution in the prior art, and then improves the steady of plasma sample
It is qualitative.
When blood plasma needs shift experiment, sealing cover 3 is opened, it can be by blood plasma in liquid storage cylinder 22 using liquid-transfering gun or suction pipe
It draws, transfer；When blood plasma needs storage, sealing cover 3, tube body 2, sealing-plug 1 and test tube 4 will be stored as a whole, be avoided
The case where in the prior art blood plasma is susceptible to pollution.
As shown in figure 5, the outer wall of above-mentioned tubular body 2 is provided with buckle 24, the end of test tube 4 can be pressed on by buckling 24 bottom surface
Face.When buckle 24 encounters test tube 4, it is meant that filter, the process of separated plasma has been completed.Since the blood in test tube 4 is
There is certain volume, buckle 24 can be adjusted in the position of tube body 2 according to actual conditions, therefore can pass through control card
The position of button 24 determines depression depths, to realize quantitative draw blood, is conducive to control filtration volume.It is buckled by being arranged
24 so that the pressure of imbibition partition board 12 reduces the incidence of haemolysis sample less than red blood cell.
As Figure 7-8, since the inner wall of sealing cover 3 is provided with the helicitic texture for being threadedly connected to tube body 2, in order to
Ensure that the sealing effect of sealing cover 3 and tube body 2, the inner wall of sealing cover 3 are provided with sealing ring 32.The material of wherein sealing ring 32 is
Rubber or silica gel etc..Meanwhile the outer wall of sealing cover 3 is provided with several non-skid threads 31, personnel easy to operation screw sealing cover 3.
When sealing cover 3 screws a circle, liquid storage cylinder 22 is communicated with external pressure, therefore can be by sealing cover 3, tube body 2 and sealing-plug 1
Entirety is pressed downward, and will complete filter process in blood indentation pipette 11.After the completion of blood filtration, sealing cover 3 is screwed,
So that the case where liquid storage cylinder 22 and external pressure completely cut off, prevent blood plasma from polluting.
Obviously, the above embodiment of the present invention is just for the sake of clearly illustrating examples made by the present invention, and it is pair to be not
The restriction of embodiments of the present invention.For those of ordinary skill in the art, may be used also on the basis of the above description
To make other variations or changes in different ways.There is no necessity and possibility to exhaust all the enbodiments.It is all this
All any modification, equivalent and improvement etc., should be included in the claims in the present invention made by within the spirit and principle of invention
Protection domain within.
Claims (10)
1. a kind of filter device of blood, which is characterized in that including：
Sealing cover (3)；
Sealing-plug (1), the sealing-plug (1) can hermetically be stretched into the test tube (4) for being equipped with blood, the sealing-plug (1)
It is internally provided with the pipette (11) for draw blood；
One end of tube body (2), the tube body (2) is connected to the sealing-plug (1), and the other end is connected to the sealing cover (3), institute
State and be provided with filter membrane (21) between sealing-plug (1) and the tube body (2), the tube body (2) be internally provided with liquid storage cylinder (22) and
One end of connecting tube (23), the connecting tube (23) is communicated in the pipette (11), and the other end is set to the liquid storage cylinder
(22) in.
2. the filter device of blood according to claim 1, which is characterized in that the bottom of the sealing-plug (1) is provided with
It is communicated in the imbibition partition board (12) of the pipette (11).
3. the filter device of blood according to claim 2, which is characterized in that the imbibition partition board (12) is that cone is tied
Structure, and bigbore one end of the imbibition partition board (12) is arranged far from the pipette (11).
4. the filter device of blood according to claim 1, which is characterized in that be provided with and be located on the sealing-plug (1)
Section distributing damper (13) below the filter membrane (21), the section distributing damper (13) is for concave structure and to far from described
The direction of filter membrane (21) is recessed, and the section distributing damper (13) is respectively communicated in the pipette (11) and the connecting tube
(23)。
5. the filter device of blood according to claim 4, which is characterized in that the pipette (11) is set to described cut
The circumferential direction of the center of face distributing damper (13), pipette (11) described in section distributing damper (13) upper edge is uniformly arranged
There are several blades (14).
6. the filter device of blood according to claim 5, which is characterized in that the shape of the blade (14) is spiral knot
Structure.
7. the filter device of blood according to claim 5, which is characterized in that the input end of the connecting tube (23) is arranged
In the marginal position of the section distributing damper (13).
8. the filter device of blood according to claim 1, which is characterized in that the outer wall of the tube body (2) is provided with card
It detains (24), the bottom surface of the buckle (24) can press on the top surface of the test tube (4).
9. the filter device of blood according to claim 1, which is characterized in that the outer wall of the sealing cover (3) is provided with
Several non-skid threads (31).
10. the filter device of blood according to claim 1, which is characterized in that the inner wall of the sealing cover (3) is provided with
Sealing ring (32).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810600680.9A CN108760455B (en) | 2018-06-12 | 2018-06-12 | Blood filtering device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810600680.9A CN108760455B (en) | 2018-06-12 | 2018-06-12 | Blood filtering device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN108760455A true CN108760455A (en) | 2018-11-06 |
| CN108760455B CN108760455B (en) | 2021-01-01 |
Family
ID=64021141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810600680.9A Active CN108760455B (en) | 2018-06-12 | 2018-06-12 | Blood filtering device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108760455B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114459871A (en) * | 2022-02-25 | 2022-05-10 | 武汉兰丁云医学检验实验室有限公司 | Sealed sample collecting and filtering device |
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| CN105722576A (en) * | 2013-11-14 | 2016-06-29 | 生物梅里埃公司 | Novel filter medium for obtaining plasma, and associated filtration device and method |
| CN106404637A (en) * | 2016-10-08 | 2017-02-15 | 重庆医科大学附属永川医院 | Hemocyte analyzer for medical detection |
| CN107684774A (en) * | 2017-09-29 | 2018-02-13 | 广州市雷德生物科技有限公司 | A kind of filter |
| CN107760593A (en) * | 2016-08-19 | 2018-03-06 | 付士明 | The evacuated blood collection tube of storage and transport circle nucleic acid sample |
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2018
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Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1780583A (en) * | 2003-04-25 | 2006-05-31 | 积水化学工业株式会社 | Method and tool for filtrating specimen using specimen sampling container, and specimen sampling container |
| CN101822854A (en) * | 2010-05-06 | 2010-09-08 | 北京航空航天大学 | Front diversing flow rotor structure with tapping splitter blades for artificial heart blood pump |
| CN202725038U (en) * | 2012-06-14 | 2013-02-13 | 山东耀华医疗器械科技有限公司 | Blood corpuscle and blood plasma separating device for trace blood collection |
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| CN107760593A (en) * | 2016-08-19 | 2018-03-06 | 付士明 | The evacuated blood collection tube of storage and transport circle nucleic acid sample |
| CN106404637A (en) * | 2016-10-08 | 2017-02-15 | 重庆医科大学附属永川医院 | Hemocyte analyzer for medical detection |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114459871A (en) * | 2022-02-25 | 2022-05-10 | 武汉兰丁云医学检验实验室有限公司 | Sealed sample collecting and filtering device |
| CN114459871B (en) * | 2022-02-25 | 2022-09-13 | 武汉兰丁云医学检验实验室有限公司 | Sealed sample collecting and filtering device |
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| Publication number | Publication date |
|---|---|
| CN108760455B (en) | 2021-01-01 |
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