CN208598576U - A kind of rat is easy controllably to continue smog exposure test device - Google Patents
A kind of rat is easy controllably to continue smog exposure test device Download PDFInfo
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- CN208598576U CN208598576U CN201721188820.3U CN201721188820U CN208598576U CN 208598576 U CN208598576 U CN 208598576U CN 201721188820 U CN201721188820 U CN 201721188820U CN 208598576 U CN208598576 U CN 208598576U
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Abstract
The utility model discloses a kind of easy controllable persistently smog exposure test devices of rat, including aerosol producer, smog mixer, smog exposure chamber, the aerosol producer connects smog mixer, the smog mixer is provided with the first air inlet, the second air inlet and smog exposure outlet, first air inlet connects aerosol producer, second air inlet connects oxygen cathete, is connected between smog exposure outlet and smog exposure chamber with pipeline；The intracavitary setting mouse frame of the smog exposure, smog exposure chamber are provided with exhaust smoke hole.Operation while the smog exposure system of the utility model setting can support four mouse framves, 2 smog exposure chamber, accommodate up to 40 test rats, the smoke exposure device capacity expansion passed through compared with market 2 times or more；And the controllability of smokescope and oxygen content is realized, so that test technology condition becomes stable controllably, and there is scalability, extremely flexibly, high-efficiency and economic.
Description
Technical field
The utility model relates to the easy controllable persistently smog exposure test dresses of medical instruments field more particularly to a kind of rat
It sets.
Background technique
Due to air pollution, chronic obstructive pulmonary disease, the illness such as pneumonia are in high-incidence trend.It is expected that China's respiratory medicine will be with 10%
Increasing rate.Simulation clinical patient Inhalation mode be in new drug development animal modeling and Pathologic Study in it is necessary
Means.Existing country's systemic exposure inhalant smog exposure system or equipment, there are many disadvantages, such as: occupied area is excessive；
Animal capacity is too small, general only more than ten, causes experimental period too long；Cost of equipment is expensive；Most important shortage is to model
The monitoring of set up the condition whole cannot be observed, being difficult to distinguish after animal model is as caused by smog only for cigarette oxygen deprivation
Pathological change changes caused by still suffocating, and death occur in animals during the experiment under serious situation, and experiment is caused to be imitated
Rate is lower.
Therefore, a kind of smog exposure system inexpensive, controllability is good is developed, smog exposure and systemic exposure are sucked
It is most important for test.
Utility model content
The purpose of this utility model is to provide a kind of easy controllable persistently smog exposure test device of rat, the system energy
Continue controllably to carry out smog exposure, so as to overcome the problems existing in the prior art.
In order to achieve the goal above, the technical solution of the utility model is:
A kind of easy controllable persistently smog exposure test device of rat, including aerosol producer, smog mixer, smog are sudden and violent
Reveal chamber, the aerosol producer connects smog mixer, and the smog mixer is provided with the first air inlet, the second air inlet and cigarette
Mist exposure outlet, the first air inlet connect aerosol producer, and the second air inlet connects oxygen cathete, and smog exposure outlet is sudden and violent with smog
It is connected between dew chamber with pipeline；The intracavitary setting mouse frame of the smog exposure, smog exposure chamber are provided with exhaust smoke hole.
Preferably, being additionally provided with exhaust pipe at the top of the aerosol producer；The aerosol producer is smoked by one to be filled
Connection smog mixer is set, the fume extracting device side has smoke chamber, and the smoke chamber is provided with smoke inlet and smog goes out
Mouthful, smoke inlet connects aerosol producer with pipeline, and the first air inlet connects aerosol outlet port with pipeline.The details of aerosol producer
Setting and fume extracting device can make the conveying of smog more smooth, convenient, and discharge is controllable.
Preferably, the smog exposure outlet ends connect 1 ~ 2 smog exposure chamber, each smog exposure is intracavitary
1 mouse frame being arranged, mouse frame are divided into upper layer mouse frame and lower layer's mouse frame.Exposure chamber is split type, transparent cavity, convenient for operation crawl
Animal, convenient for observation animal state in real time, and can be according to demand convenient for extension.
Further, the size of animal that the upper layer mouse frame or lower layer's mouse frame accommodate is 1-10.Test the saturation of rat
Meet economy and operates the dual consideration of convenience；Compared to the general capacity in market, in the case of identical occupied area, capacity extension
2 times or more.
Preferably, the smog exposure system is placed in draught cupboard.Extra flue gas can be discharged in Ventilating cabinet in time, no
Cause ambient contamination.
Further, the oxygen cathete is connected to ventilator or oxygen cylinder, and the smog mixer can be passed through newly through oxygen cathete
Fresh air or the oxygen for testing required concentration.Fresh air or a certain concentration oxygen enter after diluting smog, this setting can obtain
To more controllabilitys, experiment condition adjustability is further enhanced；The input of oxygen, it is ensured that animal will not stop up during the experiment
Breath, it is ensured that lesser space content receives more number of animals.
Further, the pipeline of the smoke inlet includes main-inlet pipe, air branch pipe and smog branch pipe, the air branch pipe
Connect aerosol producer with smog branch pipe one end, end meets at mixing chamber, main-inlet pipe both ends connection mixing chamber and smog enter
Mouthful.Smoke inlet pipeline smog mixing chamber setting make smog initial concentration conveying refinement and it is adjustable.
Preferably, the mouse frame successively has upper bottom surface, middle bottom surface and bottom surface, said midsole face and upper layer from top to bottom
Each side of the closed silk screen of each side arrangement of mouse frame, the upper bottom surface, bottom surface and lower layer's mouse frame can be logical with the external world
Thoroughly, bottom surface and smog exposure chamber bottom surface can place experimental animal respectively in mouse frame.The level setting of mouse frame makes to meet mouse frame
Using test condition and save cost；Cavity be upper and lower two parts, it is easily operated, cavity be it is transparent, convenient for observation, mouse frame
Design places animal convenient for higher density in smaller space, and smog flows freely.
Preferably, the aerosol producer is substituted by aerosol generator.Aerosol generator can be used for systemic exposure
Sucking experiment, purposes is wider.
The utility model has the beneficial effects that: a kind of rat of the utility model is easy controllably to continue smog exposure test
Device, simple and compact equipment structure, experimental condition are flexible.The setting of smog exposure chamber and its level, mouse frame makes do not influencing to tie
Tested number is expanded in the case where structure；Facilitate the entrance concentration, smog for adjusting smog in terms of the inlet tube of oxygen cathete and smog
Concentration (oxygen content) in output flow and mixer, technique is flexible；Smog exposure chamber, be it is split type, it is normal by laboratory
Rule raising box converts, and inside sets box frame, allows animal during fumigation respectively on frame, cassette bottom activity effectively extends
Fumigation capacity.Operation while the smog exposure system of the utility model setting can support four mouse framves, 2 smog to expose chamber, most
Accommodate 40 test rats, the smoke exposure device capacity expansion passed through compared with market 2 times or more more；And realize smokescope
It extremely flexibly, is efficiently passed through with the controllability of oxygen content so that test technology condition becomes stable controllably, and has scalability
Ji.
Detailed description of the invention
Fig. 1 is the flowage structure schematic diagram of the utility model embodiment, and Fig. 2 is the structure of the utility model embodiment mouse frame
Schematic diagram.
In figure: 1- aerosol producer, 2- fume extracting device, 200- main-inlet pipe, 201- smoke inlet, 202- aerosol outlet port,
203- air branch pipe, 204- smog branch pipe, 205- mixing chamber, 21-- smoke chamber, 3- smog mixer, the first air inlet of 31-,
The second air inlet of 32-, 33- smog exposure outlet, 4- smog exposure chamber, 40- exhaust smoke hole, the upper layer 41- mouse frame, 42- lower layer mouse frame,
5- oxygen cathete, 6- exhaust pipe, 7- operation panel, 8- mouse frame, 81- upper bottom surface, bottom surface in 82-, 83- bottom surface.
Specific embodiment
In order to illustrate the technical solutions in the embodiments of the present application or in the prior art more clearly, letter will be made to embodiment below
Singly introduce.
Such as Fig. 1 ~ 2, a kind of rat is easy controllably to continue smog exposure test device, and the smog exposure system is integrally placed at
In draught cupboard, including aerosol producer 1, smog mixer 3, smog exposure chamber 4, the aerosol producer 1 connect smog mixing
Device 3, the smog mixer 3 are provided with the first air inlet 31, the second air inlet 32 and smog exposure outlet 33, the first air inlet 31
Aerosol producer 1 is connected, the second air inlet 32 connects oxygen cathete 5, with pipeline between smog exposure outlet 33 and smog exposure chamber 4
It connects, is provided with exhaust pipe 6 at the top of the aerosol producer 1；Mouse frame 8, smog exposure chamber 4 are set in the smog exposure chamber 4
It closes and surrounding is provided with exhaust smoke hole 40；The oxygen cathete 5 is connected to ventilator or oxygen cylinder (not shown), the smog
The oxygen of concentration needed for mixer 3 can be passed through fresh air or be tested through oxygen cathete 5；
The aerosol producer 1 connects smog mixer 3 by a fume extracting device 2, and 2 side of fume extracting device has cigarette
Mist chamber 21, the smoke chamber 21 are provided with smoke inlet 201 and aerosol outlet port 202, and smoke inlet 201 is sent out with pipeline connection smog
Raw device 1, the first air inlet 31 connect aerosol outlet port 202 with pipeline；The pipeline of the smoke inlet 201 include main-inlet pipe 200,
Air branch pipe 203 and smog branch pipe 204, the air branch pipe 203 connect aerosol producer 1, end with 204 one end of smog branch pipe
Mixing chamber 205 is met at, 200 both ends of main-inlet pipe connect mixing chamber 205 and smoke inlet 201；
33 ends of smog exposure outlet connect 1 ~ 2 smog exposure chamber 4, setting in each smog exposure chamber 4
1 mouse frame 8, mouse frame 8 divides for upper layer mouse frame 41 and lower layer's mouse frame 42, and the upper layer mouse frame 41 or lower layer's mouse frame 42 accommodate dynamic
Object quantity is 1-10；The mouse frame 8 successively has upper bottom surface 81, middle bottom surface 82 and bottom surface 83, said midsole face from top to bottom
82 and upper layer mouse frame 41 the closed silk screen of each side arrangement, the upper bottom surface 81, bottom surface 83 and lower layer's mouse frame 42 it is each
A side can be penetrating with the external world, and the bottom surface of the middle bottom surface 82 of mouse frame and smog exposure chamber 4 can place experimental animal respectively.
In addition, the aerosol producer 1 is substituted by aerosol generator.
Operating method:
(1), aerosol producer switch is opened, the panel of aerosol producer is operated, smog takes place；Setup parameter, really
The ratio for determining air branch pipe and smog branch air in tube and smog obtains level-one smog；
(2), control aerosol producer exports quantitative level-one smog, and is transported to smog mixing chamber, and smog occurs
Device frequency and stroke can be set；
(3), the level-one smog in (2) is pipelined in mixer, while oxygen cathete inputs quantitative fresh sky
Gas or the oxygen for testing required concentration, mix in mixer with level-one smog, obtain secondary smoke；
(4), the secondary smoke input smog exposure chamber, after animal breath, remaining smog continues sudden and violent by smog
Reveal the exhaust smoke hole on cavity, be continuously discharged in external environment, and by draught cupboard, exhausting discharge.
Above embodiments are only to illustrate the optimal technical scheme of the utility model, it is noted that for the art
Those of ordinary skill for, without departing from the principle of this utility model, several improvement made or equivalent replacement,
It is accordingly to be regarded as the protection scope of the utility model, should be covered in the scope of the claims of the utility model.
Claims (9)
1. a kind of rat is easy controllably to continue smog exposure test device, which is characterized in that mixed including aerosol producer, smog
Device, smog exposure chamber, the aerosol producer connect smog mixer, and the smog mixer is provided with the first air inlet, second
Air inlet and smog exposure outlet, the first air inlet connect aerosol producer, and the second air inlet connects oxygen cathete, and smog exposes
It is connected between mouth and smog exposure chamber with pipeline；The intracavitary setting mouse frame of the smog exposure, smog exposure chamber are provided with exhaust smoke hole.
2. a kind of rat according to claim 1 is easy controllably to continue smog exposure test device, which is characterized in that described
Exhaust pipe is additionally provided at the top of aerosol producer；The aerosol producer connects smog mixer by a fume extracting device, described
Fume extracting device side has smoke chamber, and the smoke chamber is provided with smoke inlet and aerosol outlet port, and smoke inlet is connected with pipeline
Aerosol producer, the first air inlet connect aerosol outlet port with pipeline.
3. a kind of rat according to claim 1 is easy controllably to continue smog exposure test device, which is characterized in that described
Smog exposure outlet ends connect 1 ~ 2 smog exposure chamber, 1 mouse frame of the intracavitary setting of each smog exposure, mouse frame point
For upper layer mouse frame and lower layer's mouse frame.
4. a kind of rat according to claim 3 is easy controllably to continue smog exposure test device, which is characterized in that described
The size of animal that upper layer mouse frame or lower layer's mouse frame accommodate is 1-10.
5. a kind of rat according to claim 1 is easy controllably to continue smog exposure test device, which is characterized in that described
Smog exposure system is placed in draught cupboard.
6. a kind of rat according to claim 1 is easy controllably to continue smog exposure test device, which is characterized in that described
Oxygen cathete is connected to ventilator or oxygen cylinder, concentration needed for the smog mixer can be passed through fresh air or be tested through oxygen cathete
Oxygen.
7. a kind of rat according to claim 2 is easy controllably to continue smog exposure test device, which is characterized in that described
The pipeline of smoke inlet includes main-inlet pipe, air branch pipe and smog branch pipe, and the air branch pipe is connected with smog branch pipe one end
Aerosol producer, end meet at mixing chamber, and main-inlet pipe both ends connect mixing chamber and smoke inlet.
8. a kind of rat according to claim 3 is easy controllably to continue smog exposure test device, which is characterized in that described
Mouse frame successively has upper bottom surface, middle bottom surface and bottom surface, each side arrangement envelope in said midsole face and upper layer mouse frame from top to bottom
Each side of the silk screen closed, the upper bottom surface, bottom surface and lower layer's mouse frame can be penetrating with the external world, and bottom surface is sudden and violent with smog in mouse frame
Dew chamber bottom surface can place experimental animal respectively.
9. a kind of rat according to claim 1 is easy controllably to continue smog exposure test device, the aerosol producer
It is substituted by aerosol generator.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721188820.3U CN208598576U (en) | 2017-09-18 | 2017-09-18 | A kind of rat is easy controllably to continue smog exposure test device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721188820.3U CN208598576U (en) | 2017-09-18 | 2017-09-18 | A kind of rat is easy controllably to continue smog exposure test device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208598576U true CN208598576U (en) | 2019-03-15 |
Family
ID=65658704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201721188820.3U Active CN208598576U (en) | 2017-09-18 | 2017-09-18 | A kind of rat is easy controllably to continue smog exposure test device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN208598576U (en) |
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2017
- 2017-09-18 CN CN201721188820.3U patent/CN208598576U/en active Active
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