CN208436439U - A kind of jacketed sintered meshwork chassis chromatographic column - Google Patents
A kind of jacketed sintered meshwork chassis chromatographic column Download PDFInfo
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- CN208436439U CN208436439U CN201820633169.4U CN201820633169U CN208436439U CN 208436439 U CN208436439 U CN 208436439U CN 201820633169 U CN201820633169 U CN 201820633169U CN 208436439 U CN208436439 U CN 208436439U
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- chromatographic column
- collet
- cylinder
- lower head
- jacket
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Abstract
The utility model provides a kind of jacketed sintered meshwork chassis chromatographic column, it include: cylinder, upper cover, lower head, collet, it is sintered Dropbox, feed inlet, discharge port, jacket inlet, jacket outlet, waste residue outlet, visor, nitrogen mouth, vacuum port, filler entrance and head tank, the upper cover, cylinder and lower head are sequentially connected with to form chromatographic column main body, nitrogen mouth is respectively equipped on upper cover, vacuum port, feed inlet and visor, head tank is connected by pipeline with feed inlet, filler entrance is arranged in cylinder upper side, collet is set in the outside of the cylinder, jacket inlet and jacket outlet are respectively equipped on collet, lower head side is provided with discharge port, the bottom surface of lower head is equipped with waste residue outlet, the inside of lower head and discharge port corresponding position are welded with sintering Dropbox.The utility model can make to discharge more convenient, and production efficiency is higher.
Description
Technical field
The utility model relates to a kind of separators of chemical field more particularly to a kind of jacketed sintered meshwork chassis to chromatograph
Column.
Background technique
Column chromatography technology is the technology separated using chromatographic column to biomolecule, and wherein chromatographic column is common main body
Structure, chromatographic technique are divided into adsorption chromatography, Partition Chromatography, ion-exchange chromatography, gel permeation chromatography, affine by the mechanism of chromatography
Chromatography, hydrophobic chromatography etc., adsorption chromatography are the difference using adsorbent surface to different component absorption property, reach separation identification
Purpose, Partition Chromatography be it is different using distribution coefficient of the different component between mobility and stationary phase, be allowed to separate, ion
Displacement chromatography is to be allowed to separate to the difference of ion-exchanger affinity using different component, and gel chromatography is using certain solidifying
Glue for the component retardation of different molecular size difference and be allowed to separate, affinity chromatography be have in a pair it is single-minded mutual
In the substance of effect, one of them is coupled on the support, for purifying opposite another substance.
Chromatographic technique is a kind of very high separation means of separative efficiency, it can be by various properties and its similar substance point
It leaves, it not only can be used for analyzing and identifying for a small amount of substance, but also can be used for big quantity of material isolate and purify preparation, current this skill
Art is widely used to scientific research and industrial multiple fields, in petroleum, chemical industry, medical and health, bioscience, environment
The fields such as science, agricultural sciences all play an important role.
Presently used chromatographic column is generally glass tube or stainless steel tube, and the both ends of chromatographic column are only allowed by filter membrane
Mobile phase passes through, solid phase, that is, column chromatographic stuffing such as silica gel etc., cannot be detained by filter membrane and in chromatographic column, thus
Its due centrifugation is played, so, it is desirable to which the filler cleared up in chromatographic column then becomes inconvenient, especially answers
With chromatographic column relatively large in the industrial production, needed replacing after each use the filler in column all remove chromatographic column again
Bottom bulkhead, and the filler of large-scale chromatographic column is also not easy to clean up, therefore the filler cleared up in chromatographic column becomes one
Work that is extremely difficult, wasting time.
Utility model content
The technical problem to be solved by the utility model is in view of the drawbacks of the prior art, providing a kind of jacketed sintering
Net bottom disk chromatographic column.
The utility model uses following technical scheme to solve above-mentioned technical problem: a kind of jacketed sintered meshwork chassis chromatography
Column, comprising: cylinder, upper cover, lower head, collet, sintering Dropbox, feed inlet, discharge port, jacket inlet, jacket outlet, waste residue
Outlet, visor, nitrogen mouth, vacuum port, filler entrance and head tank, the upper cover, cylinder and lower head are sequentially connected with to be formed
Chromatographic column main body is respectively equipped with nitrogen mouth, vacuum port, feed inlet and visor on the upper cover, and the head tank passes through pipeline
It is connected with feed inlet, the filler entrance is arranged in cylinder upper side, and the collet is set in the outside of the cylinder, institute
It states and is respectively equipped with jacket inlet and jacket outlet on collet, the lower head side is provided with discharge port, and the bottom surface of lower head is equipped with
Waste residue outlet, the inside of lower head and discharge port corresponding position are welded with sintering Dropbox.
Particularly, the cylinder, upper cover and lower head are stainless steel material.
Particularly, the jacket inlet is in collet lower side, and the jacket outlet is in collet upper side.
Particularly, the collet is internally provided with the coil pipe around the cylinder.
Particularly, the lowest point of the discharge port is consistent with the lowest point height of lower head.
Particularly, the waste residue outlet is connected with hydraulic control device, controls waste residue outlet by hydraulic control device
Opening and closing.
Particularly, the nitrogen mouth, vacuum port, feed inlet, filler entrance and discharge port are equipped with valve.
Particularly, the sintering Dropbox is stainless steel material.
Particularly, there is liquidometer in the head tank side.
The utility model is had the following technical effect that compared with prior art using above technical scheme
The utility model by chromatographic column lower weld be sintered Dropbox, so that chromatographic column is able to bear bigger pressure, from
And the working efficiency of chromatographic column is improved to a certain extent, while bottom opens up the waste residue outlet controlled by hydraulic device, it can
Make to discharge more convenient, nitrogen mouth can make the utility model more efficient when clearing up filler waste residue, it is not necessary to carry out numerous
Trivial manual operation is also not easy the difficult situation of waste residue discharging occur.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the utility model.
In figure: 1- cylinder, 2- upper cover, 3- lower head, 4- collet, 5- are sintered Dropbox, 6- feed inlet, 7- discharge port, 8-
Jacket inlet, 9- jacket outlet, 10- waste residue outlet, 11- visor, 12- nitrogen mouth, 13- vacuum port, 14 filler entrances, 15- high
Position slot
Specific embodiment
The technical solution of the utility model is described in further detail with reference to the accompanying drawing.
A kind of jacketed sintered meshwork chassis chromatographic column, comprising: cylinder 1, upper cover 2, lower head 3, collet 4, sintering Dropbox
5, feed inlet 6, discharge port 7, jacket inlet 8, jacket outlet 9, waste residue outlet 10, visor 11, nitrogen mouth 12, vacuum port 13, fill out
Material entrance 14 and head tank 15, the upper cover 2, cylinder 1 and lower head 3 are sequentially connected with to form chromatographic column main body, the upper envelope
Nitrogen mouth 12, vacuum port 13, feed inlet 6 and visor 11 are respectively equipped on first 1, the head tank 15 passes through pipeline and feed inlet 6
It is connected, the filler entrance 14 is arranged in 1 upper side of cylinder, and the collet 4 is set in the outside of the cylinder 1, described
Jacket inlet 8 and jacket outlet 9 are respectively equipped on collet 4,3 side of lower head is provided with discharge port 7, the bottom surface of lower head 3
Equipped with waste residue outlet 10, the inside of lower head 3 and 7 corresponding position of discharge port are welded with sintering Dropbox 5.
Particularly, the cylinder 1, upper cover 2 and lower head 3 are stainless steel material.
Particularly, the jacket inlet 8 is in 4 lower side of collet, and the jacket outlet 9 is in 4 upper side of collet
Particularly, the collet 4 is internally provided with the coil pipe around cylinder 1.
Particularly, the lowest point of the discharge port 7 and the lowest point height of lower head 3 are consistent.
Particularly, the waste residue outlet 10 is connected with hydraulic control device, controls waste residue outlet by hydraulic control device
10 opening and closing.
Particularly, the nitrogen mouth 12, vacuum port 13, feed inlet 6, filler entrance 14 and discharge port 7 are equipped with valve.
Particularly, the sintering Dropbox 5 is stainless steel material.
Particularly, 15 side of head tank is equipped with liquidometer.
As a kind of usage mode of the utility model, specifically it is summarized as follows:
Waste residue outlet 10 is closed, filler is added by filler entrance 14, filler charging is finished, can be observed by visor 11
Whether filler fills normally, if abnormal can be internal by the leveling of bottom gas fluid effect by opening 13 valve of vacuum port
Filler closes valve at filler entrance 14, opens feed inlet 6, and treating material is entered in cylinder 1 by head tank 15, passed through
The liquidometer of head tank 15 can calculate inventory and close the valve of feed inlet 6 in time, material by the filler in cylinder 1 into
Line number time absorption and desorption, final goal product flow out into next workshop section from discharge port 7, can pass through in chromatography process
It opens 12 valve of nitrogen mouth and carries out pressurization appropriate, accelerate chromatography progress, required when reaching chromatography, close the valve of discharge port 7,
Waste residue outlet 10 is opened by control hydraulic device, while opening big 12 valve of nitrogen mouth, is gone out filler using nitrogen, lower head
3 inner walls, which correspond to, to be welded with sintering Dropbox 5 and can filter out product, reservation is filled out by being sintered Dropbox 5 at the position of discharge port 7
Material, simultaneously as being to be welded and fixed, it is possible to instead of conventional filter paper filter cloth, not need every batch of replacement, reduce manual operation.
If material requires temperature in chromatography process, can will be added by opening jacket inlet 8 and jacket outlet 9
Heat or cooling medium are passed through inside collet 4, and coil pipe is arranged inside collet 4 effectively to be rectified heat transfer medium, while
The impurity in medium is avoided to block jacket inlet 8 or corrosion 4 inner wall of collet, to achieve the purpose that control column body temperature.
Specific embodiment of the utility model is described in detail above, but it is only used as example, the utility model
It is not restricted to particular embodiments described above.To those skilled in the art, any that this practical is equal
Modifications and substitutions are also all among the scope of the utility model.Therefore, the institute under the spirit and scope for not departing from the utility model
The equal transformation and modification of work, should all cover in the scope of the utility model.
Claims (9)
1. a kind of jacketed sintered meshwork chassis chromatographic column characterized by comprising cylinder (1), upper cover (2), lower head (3),
Collet (4), sintering Dropbox (5), feed inlet (6), discharge port (7), jacket inlet (8), jacket outlet (9), waste residue outlet (10),
Visor (11), nitrogen mouth (12), vacuum port (13), filler entrance (14) and head tank (15), the upper cover (2), cylinder (1)
It is sequentially connected with to form chromatographic column main body with lower head (3), is respectively equipped with nitrogen mouth (12), vacuum port on the upper cover (2)
(13), feed inlet (6) and visor (11), the head tank (15) are connected by pipeline with feed inlet (6), the filler entrance
(14) it is arranged in cylinder (1) upper side, the collet (4) is set in the outside of the cylinder (1), divides on the collet (4)
Not She You jacket inlet (8) and jacket outlet (9), lower head (3) side is provided with discharge port (7), the lower head (3)
Bottom surface is equipped with waste residue outlet (10), and the inside of the lower head (3) and the discharge port (7) corresponding position are welded with sintering Dropbox
(5)。
2. a kind of jacketed sintered meshwork chassis according to claim 1 chromatographic column, which is characterized in that the cylinder (1), on
End socket (2) and lower head (3) are stainless steel material.
3. a kind of jacketed sintered meshwork chassis according to claim 1 chromatographic column, which is characterized in that the jacket inlet
(8) in collet (4) lower side, the jacket outlet (9) is in collet (4) upper side.
4. a kind of jacketed sintered meshwork chassis according to claim 1 chromatographic column, which is characterized in that in the collet (4)
Portion is equipped with coil pipe around cylinder (1).
5. a kind of jacketed sintered meshwork chassis according to claim 1 chromatographic column, which is characterized in that the discharge port (7)
Lowest point it is consistent with the lowest point height of lower head (3).
6. a kind of jacketed sintered meshwork chassis according to claim 1 chromatographic column, which is characterized in that the waste residue outlet
(10) it is connected with hydraulic control device, passes through the opening and closing of hydraulic control device control waste residue outlet (10).
7. a kind of jacketed sintered meshwork chassis according to claim 1 chromatographic column, which is characterized in that the nitrogen mouth
(12), vacuum port (13), feed inlet (6), filler entrance (14) and discharge port (7) are equipped with valve.
8. a kind of jacketed sintered meshwork chassis according to claim 1 chromatographic column, which is characterized in that the sintering Dropbox
It (5) is stainless steel material.
9. a kind of jacketed sintered meshwork chassis according to claim 1 chromatographic column, which is characterized in that the head tank (15)
Side is equipped with liquidometer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820633169.4U CN208436439U (en) | 2018-04-28 | 2018-04-28 | A kind of jacketed sintered meshwork chassis chromatographic column |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820633169.4U CN208436439U (en) | 2018-04-28 | 2018-04-28 | A kind of jacketed sintered meshwork chassis chromatographic column |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208436439U true CN208436439U (en) | 2019-01-29 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201820633169.4U Active CN208436439U (en) | 2018-04-28 | 2018-04-28 | A kind of jacketed sintered meshwork chassis chromatographic column |
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| CN (1) | CN208436439U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113117380A (en) * | 2019-12-31 | 2021-07-16 | 江苏汉邦科技有限公司 | Novel chromatographic column and unloading method |
-
2018
- 2018-04-28 CN CN201820633169.4U patent/CN208436439U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113117380A (en) * | 2019-12-31 | 2021-07-16 | 江苏汉邦科技有限公司 | Novel chromatographic column and unloading method |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CP03 | Change of name, title or address |
Address after: 201400 Shanghai Fengxian District Chugong Road 388 7 Building 1 Floor Patentee after: Shanghai Wanshou Pharmaceutical Co., Ltd. Address before: 201499 Fengxian District, Fengxian Chemical Industry Zone, Shanghai Patentee before: Shanghai Wanshuo Chemistry Co., Ltd. |
|
| CP03 | Change of name, title or address |