CN208287002U - For the fixed device with anesthesia of mouse magnetic resonance - Google Patents

For the fixed device with anesthesia of mouse magnetic resonance Download PDF

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Publication number
CN208287002U
CN208287002U CN201721125082.8U CN201721125082U CN208287002U CN 208287002 U CN208287002 U CN 208287002U CN 201721125082 U CN201721125082 U CN 201721125082U CN 208287002 U CN208287002 U CN 208287002U
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CN
China
Prior art keywords
mouse
solid
ear
mouth
magnetic resonance
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Expired - Fee Related
Application number
CN201721125082.8U
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Chinese (zh)
Inventor
潘奇
杨枫
罗春海
曲原飞
任顾群
李桂荣
张海良
吕秀花
侯炜寰
李凯旋
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Second Affiliated Hospital of Xian Medical University
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Second Affiliated Hospital of Xian Medical University
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Priority to CN201721125082.8U priority Critical patent/CN208287002U/en
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Abstract

The utility model provides a kind of device fixed for mouse magnetic resonance with anesthesia, belongs to the field of medical instrument technology.Postanesthetic mouse is placed in mouse place position when use, pass through solid mouth device and the fixed mouse of solid ear device, in magnetic resonance examination experimentation, persistently lead to the oxygen of low discharge to mouse by oxygen catheter, prevent mouse dead in resonance examination procedure, when such as mouse revival, in the case where not changing mouse position, swivel tee pipe, anesthetic is conveyed in real time by anesthetic conduit, mouse is anaesthetized in realization in real time, both it had realized and the long-time of mouse had been fixed, in turn avoid the problem of disposable excessive anesthetic leads to dead mouse, and for the fixed apparatus structure compact and reasonable with anesthesia of mouse magnetic resonance, it realizes and the matching of experiment magnetic resonance examination coil, improve magnetic resonance examination experiment success rate.

Description

For the fixed device with anesthesia of mouse magnetic resonance
Technical field
It is specially a kind of for the fixed dress with anesthesia of mouse magnetic resonance the utility model relates to the field of medical instrument technology It sets.
Background technique
What science and technology was maked rapid progress is constantly progressive, and along with being increasing for medical inspection means, magnetic resonance is increasingly More is applied in clinical examination and experimental study, but in existing many research achievements, still can not solve and answer and is big The mechanism that Partial tumors venereal disease becomes, however people increasingly thirst for these problems to obtain answer, therefore researcher is not It is disconnected to be desirable to find answer with the experimental animals such as mouse, to capture the tumor disease for endangering human health.Research Personnel plant in the animal bodies such as mouse and marked tumor cell, it is desirable to by the advanced inspection equipment such as magnetic resonance, understand small Tumour cell is labeled in mouse body in the Variation Features of cellular elements level, to disclose the generation and development of neoplastic lesion Mechanism.
In carrying out mouse magnetic resonance examination, under certain magnetic field strength, sweep time length determines the contrast of image, During especially mouse magnetic resonance examination experimental study checks, scanning sequence is more, and the time is longer, generally mostly in half an hour or more. The fixation device that the prior art provides can not long-time stable fixation mouse, dead mouse is not in order to prevent during the inspection process The energy a large amount of anesthetic of first use, in addition, the coil requirement that magnetic resonance examination is special, the fixed experiment porch of common mouse is because of body Product is larger and can not match with experiment magnetic resonance examination coil, the higher scan image of resolution ratio is unable to get, to understand Certainly the above problem needs a kind of for the fixed device with anesthesia of mouse magnetic resonance.
Utility model content
Aiming at the problems existing in the prior art, the utility model provides a kind of for mouse magnetic resonance fixation and anesthesia Device can stablize fixed mouse, and carry out persistent low flow oxygen supply to mouse, in case of mouse is revived in magnetic resonance examination experiment It wakes up, mouse can be anaesthetized in real time in the case where not changing mouse position, so that advantageous ensure that magnetic resonance examination Experiment success rate.
The utility model is to be achieved through the following technical solutions:
For the fixed device with anesthesia of mouse magnetic resonance, comprising: mounting platform, solid ear device, solid mouth device, upper end Lid, anesthetic conduit and oxygen catheter;
Mouse place position is provided on one end of the mounting platform, Gu ear device is located at two sides and the peace of mouse place position Assembling platform connection, Gu ear device is used for the fixed mouse of earhole by mouse;
One end that the solid mouth device is located at end of the mouse place position far from mounting platform is connected with mounting platform, Gu Mouth device is used for through the fixed mouse of mouse oral area;
The top that the upper end cover is located at solid mouth device is connected with mounting platform, and upper end cover is close to one end of mouse place position It is provided with solid mouth gap, the other end is connected by triple valve with anesthetic conduit and oxygen catheter.
Optionally, the solid ear device includes: solid ear stick, solid ear sliding block and support frame;
Support frame as described above is connected with mounting platform, Gu ear sliding block and support frame are slidably connected, Gu ear sliding block can support It is slided along the vertical direction on frame;
The solid ear stick and solid ear sliding block are slidably connected, Gu ear stick can slide in the horizontal direction on solid ear sliding block, Gu One end of ear stick is provided with top, and solid the top of ear stick on the solid ear device of mouse place position two sides is oppositely arranged.
Optionally, adjusting screw is provided on support frame as described above and solid ear sliding block.
Optionally, the solid mouth device includes: top board, lower platen, solid mouth sliding block and solid mouth mounting blocks;
The solid mouth mounting blocks are connected with mounting platform, Gu mouth sliding block and solid mouth mounting blocks are slidably connected, Gu mouth sliding block exists Gu can be slided along mounting platform length direction on mouth mounting blocks;
One end of the solid mouth sliding block is provided with sliding slot, and one end of lower platen is mounted in the sliding slot, and lower platen is in cunning It can be slided along the vertical direction in slot, the top that top board is located at lower platen is connected with lower platen.
Optionally, the top board and lower platen are bolted, and spring is provided between top board and lower platen.
Optionally in described consolidate on mouth mounting blocks and solid mouth sliding block is provided with adjusting screw.
Optionally, mounting platform, solid ear device, solid mouth device, upper end cover, anesthetic conduit and oxygen catheter are all made of modeling Material, resin, rubber, aluminium alloy or titanium alloy material are made.
Compared with prior art, the utility model has technical effect beneficial below:
Provided by the utility model fixed with the device anaesthetized for mouse magnetic resonance, when use, sets postanesthetic mouse In mouse place position, oxygen catheter is passed through in resonance examination procedure by solid mouth device and the fixed mouse of solid ear device Continue the oxygen that the mouse into anesthesia leads to low discharge, prevents mouse dead in magnetic resonance examination experimentation, magnetic resonance inspection During looking into, if mouse revives, in the case where not changing position, swivel tee pipe is conveyed in real time by anesthetic conduit Anesthetic, realization anaesthetize mouse in real time, have both realized and fixed to the long-time of mouse, in turn avoided disposable excessive fiber crops Liquor-saturated dose of the problem of leading to dead mouse, and it is fixed with the apparatus structure compact and reasonable anaesthetized for mouse magnetic resonance, it realizes With the experiment matching of magnetic resonance examination coil, magnetic resonance examination experiment success rate is improved.
Further, pass through the solid ear sliding block being slidably connected with support frame and the solid ear being slidably connected with solid ear sliding block Stick realizes the adjustable of solid ear device, increases the adaptability of solid ear device, enables solid ear device for different mouse It uses.
Further, it is slidably connected down by the solid mouth sliding block that is slidably connected with solid mouth mounting blocks and with solid mouth sliding block Pressing plate realizes the adjustable of solid mouth device, increases the adaptability of solid mouth device, enables solid mouth device for different Mouse uses;
Further, since mounting platform, solid ear device, solid mouth device, upper end cover, anesthetic conduit and oxygen catheter are equal It is made of plastics, resin or rubber, aluminium alloy or titanium alloy etc materials, avoids the shadow containing ferromagnetic material to magnetic field It rings.
Detailed description of the invention
Fig. 1 is that a kind of fix for mouse magnetic resonance provided by the embodiment of the utility model is shown with the structure of the device of anesthesia It is intended to;
Fig. 2 is provided by the embodiment of the utility model a kind of for the fixed section view with the device anaesthetized of mouse magnetic resonance Figure;
Fig. 3 is a kind of structural schematic diagram of solid ear device provided by the embodiment of the utility model;
Fig. 4 is a kind of structural schematic diagram of solid mouth device provided by the embodiment of the utility model.
In figure: 1. mounting platforms, 2. solid ear devices, 3. solid mouthful devices, 4. upper end covers, 5. anesthetic conduits, 6. oxygen are led Pipe;
21. support frame, 22. solid ear sliding blocks, 23. solid ear sticks, 31. solid mouthful mounting blocks, 32. solid mouthful sliding blocks, 33. top boards, 34. lower platen.
Specific embodiment
The utility model is described in further detail below with reference to specific embodiment, described is to the utility model Explanation rather than limit.
Fig. 1 is provided by the embodiment of the utility model for the fixed schematic diagram with the device anaesthetized of mouse magnetic resonance, such as It is fixed with the device anaesthetized for mouse magnetic resonance shown in Fig. 1, comprising: mounting platform 1, solid ear device 2, solid mouth device 3, on End cap 4 and anesthetic conduit 5;Mouse place position is provided on one end of mounting platform 1, Gu ear device 2 is located at mouse place position Two sides and mounting platform 1 connect, solid ear device 2 is used for through the earhole of mouse fixation mouse;Gu mouth device 3 is put positioned at mouse The one end and mounting platform 1 for setting end of the storehouse far from mounting platform 1 connect, Gu mouth device 3 is for small by the fixation of mouse oral area Mouse;Upper end cover 4 is located at the top of solid mouth device 3 and mounting platform 1 connects, and upper end cover 4 is arranged close to one end of mouse place position There is solid mouth gap, the other end is connected by triple valve and anesthetic conduit 5 and oxygen catheter 6.
Wherein, upper end cover 4 and mounting platform 1 are to be detachably connected, and in fixed mouse, upper end cover 4 can be removed, will After the completion of mouse is fixed, upper end cover 4 is mounted on installation site, is connected for example, upper end cover 4 can be screw with mounting platform 1 Either snap connection.Since magnetic resonance examination experimental period is longer, postanesthetic mouse was easily tested in magnetic resonance examination It is dead in journey, in order to avoid dead mouse, it can be continually fed into low discharge oxygen by oxygen catheter 6, guarantee mouse survival rate, Magnetic resonance examination experiment success rate is improved, if mouse revives in resonance examination procedure, in the feelings for not changing mouse position Under condition, switching three-way valve is passed through anesthetic by anesthetic conduit 5 in real time, is anaesthetized again to mouse.
Fig. 3 is the schematic diagram of solid ear device 2 provided by the embodiment of the utility model, as shown in Fig. 2, solid ear device 2 includes: Gu ear stick 23, solid ear sliding block 22 and support frame 21;Support frame 21 and mounting platform 1 connect, Gu ear sliding block 22 and support frame 21 are sliding Dynamic connection, Gu ear sliding block 22 can slide along the vertical direction on support frame 21;Gu ear stick 23 and solid ear sliding block 22 are slidably connected, Gu ear stick 23 can slide in the horizontal direction on solid ear sliding block 22, Gu one end of ear stick 23 is provided with top, put positioned at mouse Solid the top of ear stick 23 set on the solid ear device 2 of storehouse two sides is oppositely arranged.
Wherein, support frame 21 and mounting platform 1 are vertically arranged, and connection type can be threaded connection, Gu ear sliding block 22 Covering can slide on support frame 21 along support frame 21, adjust the height of solid ear sliding block 22, make solid 23 height of ear stick and mouse ear Hole height is identical, by adjusting screw that solid ear sliding block 22 is fixed at this time;Adjust solid stretching of the ear stick 23 in solid ear sliding block 22 Amount, to guarantee that the solid ear stick 23 of two sides protrudes into the earhole of mouse, by the position for adjusting the fixed solid ear stick 23 of screw.
Fig. 4 is the schematic diagram of solid mouth device 3 provided by the embodiment of the utility model, as shown in figure 3, solid mouth device 3 includes: Top board 33, lower platen 34, solid mouth sliding block 32 and solid mouth mounting blocks 31;Gu mouth mounting blocks 31 and mounting platform 1 connect, Gu Kou is sliding Block 32 and solid mouth mounting blocks 31 are slidably connected, Gu mouth sliding block 32 can be along 1 length direction of mounting platform on solid mouth mounting blocks 31 Sliding;Gu one end of mouth sliding block 32 is provided with sliding slot, one end of lower platen 34 is mounted in the sliding slot, and lower platen 34 is in sliding slot In can slide along the vertical direction, top board 33 be located at lower platen 34 top and lower platen 34 connect.
Wherein, when fixed mouse mouth position, slide solid mouth sliding block 32 adjust top board 33 and mouse oral area it is horizontal away from From sliding top board 33 adjusts the vertical distance of top board 33 and mouse oral area, fixed solid by adjusting screw after being adjusted in place The position of mouth sliding block 32 and lower platen 34, is compressed top board 33 and lower platen 34 by bolt, fixed mouse oral area.Top board Spring is installed between 33 and lower platen 34, in order to which top board 33 and lower platen 34 reset.
The special magnetic field environment of magnetic resonance does not allow to enter etc. particular/special requirements, therefore, mounting platform containing ferromagnetic object 1, solid ear device 2, solid mouth device 3, upper end cover 4, anesthetic conduit 5 and oxygen catheter 6 are all made of plastics, resin, rubber, aluminium and close Gold or titanium alloy etc materials are made.
The above is only the preferred embodiment of the present invention, is not intended to limit the utility model, all practical at this Within novel spirit and principle, any modification, equivalent replacement, improvement and so on should be included in the guarantor of the utility model Within the scope of shield.

Claims (7)

1. for the fixed device with anesthesia of mouse magnetic resonance characterized by comprising mounting platform (1), admittedly ear device (2), Gu mouth device (3), upper end cover (4), anesthetic conduit (5) and oxygen catheter (6);
Be provided with mouse place position on one end of the mounting platform (1), Gu ear device (2) be located at mouse place position two sides and Mounting platform (1) connection, Gu ear device (2) is used for the fixed mouse of earhole by mouse;
Described solid mouth device (3) are located at one end of end of the mouse place position far from mounting platform (1) and mounting platform (1) connects It connects, Gu mouth device (3) is used for through the fixed mouse of mouse oral area;
The upper end cover (4) is located at the top of solid mouth device (3) and mounting platform (1) connection, upper end cover (4) are placed close to mouse The one end in storehouse is provided with solid mouth gap, and the other end passes through triple valve and the connection of anesthetic conduit (5) and oxygen catheter (6).
2. as described in claim 1 for the fixed device with anesthesia of mouse magnetic resonance, which is characterized in that the solid ear device It (2) include: solid ear stick (23), solid ear sliding block (22) and support frame (21);
Support frame as described above (21) and mounting platform (1) connection, Gu ear sliding block (22) and support frame (21) are slidably connected, Gu ear sliding block (22) it can be slided along the vertical direction on support frame (21);
Solid ear stick (23) and solid ear sliding block (22) are slidably connected, Gu ear stick (23) can be on solid ear sliding block (22) along level Direction sliding, Gu one end of ear stick (23) is provided with top solid ear stick on the solid ear device (2) of mouse place position two sides (23) top is oppositely arranged.
3. as claimed in claim 2 for the fixed device with anesthesia of mouse magnetic resonance, which is characterized in that support frame as described above (21) and on solid ear sliding block (22) it is provided with adjusting screw.
4. as described in claim 1 for the fixed device with anesthesia of mouse magnetic resonance, which is characterized in that the solid mouth device (3) include: top board (33), lower platen (34), consolidate mouth sliding block (32) and consolidate mouth mounting blocks (31);
Solid mouth mounting blocks (31) and mounting platform (1) connection, Gu mouth sliding block (32) and solid mouth mounting blocks (31) are slidably connected, Gu mouth sliding block (32) can slide on solid mouth mounting blocks (31) along mounting platform (1) length direction;
The one end of solid mouth sliding block (32) is provided with sliding slot, and one end of lower platen (34) is mounted in the sliding slot, lower platen (34) it can be slided along the vertical direction in sliding slot, top board (33) is located at the top of lower platen (34) and lower platen (34) connects It connects.
5. as claimed in claim 4 for the fixed device with anesthesia of mouse magnetic resonance, which is characterized in that the top board (33) it is bolted with lower platen (34), is provided with spring between top board (33) and lower platen (34).
6. as claimed in claim 4 for the fixed device with anesthesia of mouse magnetic resonance, which is characterized in that the Gu Kou installation Adjusting screw is provided on block (31) and solid mouth sliding block (32).
7. the device fixed for mouse magnetic resonance with anesthesia as described in claim 1 to 6 is any, which is characterized in that installation Platform (1), solid ear device (2), solid mouth device (3), upper end cover (4), anesthetic conduit (5) and oxygen catheter (6) are all made of modeling Material, resin, rubber, aluminium alloy or titanium alloy material are made.
CN201721125082.8U 2017-09-04 2017-09-04 For the fixed device with anesthesia of mouse magnetic resonance Expired - Fee Related CN208287002U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201721125082.8U CN208287002U (en) 2017-09-04 2017-09-04 For the fixed device with anesthesia of mouse magnetic resonance

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201721125082.8U CN208287002U (en) 2017-09-04 2017-09-04 For the fixed device with anesthesia of mouse magnetic resonance

Publications (1)

Publication Number Publication Date
CN208287002U true CN208287002U (en) 2018-12-28

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110801305A (en) * 2019-11-14 2020-02-18 西安医学院第二附属医院 Heart failure animal model induction device

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110801305A (en) * 2019-11-14 2020-02-18 西安医学院第二附属医院 Heart failure animal model induction device
CN110801305B (en) * 2019-11-14 2021-06-22 西安医学院第二附属医院 Heart failure animal model induction device

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CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20181228

Termination date: 20190904