CN208224090U - A kind of portable SPR tester - Google Patents
A kind of portable SPR tester Download PDFInfo
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- CN208224090U CN208224090U CN201820634684.4U CN201820634684U CN208224090U CN 208224090 U CN208224090 U CN 208224090U CN 201820634684 U CN201820634684 U CN 201820634684U CN 208224090 U CN208224090 U CN 208224090U
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Abstract
A kind of portable SPR tester, including SPR tester and the sampler being equipped on SPR tester, the SPR tester includes preceding cover member, the channel member being arranged in preceding cover member, the light path part being arranged in preceding cover member and the base plate part being cooperatively connected with preceding cover member, and the base plate part includes bottom plate and the waste liquid bottle being arranged on bottom plate, regenerated liquid bottle, buffer bottle and control circuit board;The channel member includes installing frame and the peristaltic pump that is fixed in installing frame;It is equipped in the preceding cover member by sample circle, described by being equipped in sample circle by sample device, the sampler bottom is equipped with coupler, and the sampler insertion is cooperatively connected by sample circle and by coupler with by sample device;The beneficial effects of the utility model are: the unique design by sample device and coupler, the feeding instrument test flow path for keeping tested sample reliable and easy, to ensure that the realization of portable SPR instrument.
Description
Technical field
The utility model relates to optical detecting instrument technical fields, and in particular to a kind of portable SPR tester.
Background technique
SPR instrument (surface plasma resonance), spy when entering the generation total reflection of light vegetable medium from optically denser medium using light
Property, SPR phenomenon is generated in the case where dielectric surface is coated with metal layer, the micro change of the substance of overlay coating will lead to refractive index
Change, measures the amount for the substance for causing it to change by detecting the change of this refractive index;By antibody or resisted by technological means
Original is tagged to coating surface, when having corresponding antigen or antibody (having specific reaction) passes through, micro antigen
Or the antibody or antigen-reactive of antibody meeting and label combine, and cause the amount of substance of mark position to change, refractive index is caused to change
Become;The sensitivity of this measuring technique can achieve nanogram rank;Because this measurement method is needed sample (liquid) from plating
The label surface of layer is flowed through with certain speed, so test macro must have a miniature flow passage system, which results in
Current SPR instrument is all desk-top design, and volume weight and Operating Complexity, which all make SPR instrument all, to be made in laboratory
With not being able to satisfy the portable requirement tested on site.
Utility model content
Aiming at the problems existing in the prior art, the utility model provides small in size, easy to carry, structurally reasonable one
The portable SPR tester of kind.
The technical solution of the utility model is as follows:
A kind of portable SPR tester, which is characterized in that including SPR tester and be equipped on SPR tester
Sampler, the SPR tester include preceding cover member, the channel member being arranged in preceding cover member, are arranged in preceding cover member
On light path part and with preceding cover member be cooperatively connected base plate part, the base plate part include bottom plate and be arranged on bottom plate
Waste liquid bottle, regenerated liquid bottle, buffer bottle and control circuit board;The channel member includes installing frame and is fixed at installation
Peristaltic pump in frame;It is equipped in the preceding cover member by sample circle, it is described to be equipped with by sample circle by sample device, the sampler
Bottom is equipped with coupler, and the sampler insertion is cooperatively connected by sample circle and by coupler with by sample device;It is described
Regenerated liquid bottle is equipped with regenerated liquid conveyance conduit, and the buffer bottle is equipped with buffer conveyance conduit, described to be set by sample device
Have a sample delivery pipeline, the regenerated liquid conveyance conduit, buffer conveyance conduit, sample delivery pipeline respectively with light path part
Entrance is connected, and the outlet of the light path part is equipped with third connecting pipe, and the third connecting pipe is equipped with peristaltic pump, described
Peristaltic pump is connected by pipeline with waste liquid bottle;Pipeline connecting parts are additionally provided on the sample delivery pipeline, and pass through piping connection
Part connection setting raffinate conveyance conduit, raffinate conveyance conduit one end is connected with pipeline connecting parts, another to terminate at third company
On adapter tube road.
A kind of portable SPR tester, which is characterized in that the buffer conveyance conduit and regenerated liquid delivery pipe
Position is equipped with tee pipe fitting between road end, and is connected by tee pipe fitting, the connection setting of sample delivery pipeline one end
By sample device, the other end is equipped with four-way pipe fitting, and connects setting raffinate conveyance conduit, the tee pipe fitting and four by four-way pipe fitting
It is equipped with the first connecting pipe between way pipe fitting, and is connected to by the first connecting pipe, is additionally provided with the second company on the four-way pipe fitting
Adapter tube road, and be connected by the second connecting pipe with the entrance of light path part.
A kind of portable SPR tester, which is characterized in that it is described by sample device include by sample device ontology and cooperation set
Set in the needle stand by sample device body bottom portion, it is described by sample device ontology include the first large cavity and setting in the first large cavity bottom and
The first small cavity being connected to the first large cavity;The coupler includes coupler ontology and is equipped at coupler ontology bottom
The rubber seal plug in portion, the coupler ontology include the second large cavity and setting the second largest cavity bottom and with the second large cavity
Second small cavity of connection;The needle stand includes needle stand ontology, the syringe needle that needle stand bodies top is arranged in and is arranged in needle stand sheet
The butt joint of body bottom is interconnected between the syringe needle and butt joint;Second large cavity is equipped in the first big chamber
In vivo, the described second small cavity is arranged in the first small cavity, and is fitted close by rubber seal plug and the first small cavity.
A kind of portable SPR tester, which is characterized in that the channel member further includes being arranged in installing frame
Buffer valve, regenerated liquid valve, the first control valve, the second control valve and sample valve, buffer valve setting is defeated in buffer
It sending on pipeline, regenerated liquid valve is arranged on regenerated liquid conveyance conduit, and the sample valve is arranged on sample delivery pipeline, and described the
One control valve is arranged on raffinate conveyance conduit, and second control valve is arranged in third connecting pipe, the buffer valve,
Sample valve and regenerated liquid valve are all made of one-way valve, and first control valve and the second control valve are all made of two-way valve.
A kind of portable SPR tester, which is characterized in that the raffinate conveyance conduit connects in third connecting pipe
Above and at the position between the second control valve and peristaltic pump.
A kind of portable SPR tester, which is characterized in that the light path part includes frame, LED light source, standard
Straight camera lens, optical filter and polarizing film, the first cylindrical mirror, the second cylindrical mirror, collimating mirror, imaging lens and cylinder-prism, the LED
Light source, collimation camera lens, optical filter and polarizing film and the first cylindrical mirror are arranged in a side position of frame, second cylindrical mirror,
Another side position of frame is arranged in collimating mirror and imaging lens, described between the cylinder-prism setting in the frame at position
Cylinder-prism is equipped with biochip, and the biochip is equipped with flow path features, and described imaging lens one end is equipped with camera,
The entrance of the light path part and outlet are separately positioned on flow path features both ends corresponding position.
A kind of portable SPR tester, which is characterized in that the preceding cover member be equipped with touch control system and
Identity card identification module, the control circuit board respectively with identity card identification module, touch control system, peristaltic pump, buffer
Valve, regenerated liquid valve, the first control valve, the second control valve and sample valve circuit connection.
A kind of portable SPR tester, which is characterized in that between first large cavity and the first small cavity
Junction constitutes position limiting structure, and after second large cavity is contacted with position limiting structure, syringe needle puncture rubber seal plug simultaneously stretches to the
The corresponding position of two small cavitys.
A kind of portable SPR tester, which is characterized in that the outer wall and rubber seal plug phase of the second small cavity
Cooperation, and coupler bottom is sealed by rubber seal plug.
A kind of portable SPR tester, which is characterized in that the needle stand is seperated with by using between sample device ontology
Structure or integral structure.
The beneficial effects of the utility model are:
1) by setting raffinate conveyance conduit, by the raffinate in sample device and sample delivery pipeline without micro- without chip
Runner can be fed directly in waste liquid pool, to solve the problems, such as sample cross contamination during follow-on test, improve survey
The accuracy of examination.
2) peristaltic pump is set in third connecting pipe, it can be residual to sample delivery pipeline and by sample device by suction function
The progress of product of keeping sample effectively is cleared up, and cleaning efficiency and cleaning effect are improved.
3) buffer conveyance conduit is equipped with buffer valve, and regenerated liquid conveyance conduit is equipped with regenerated liquid valve, sample delivery
Pipeline is equipped with sample valve, and wherein buffer valve, sample valve and regenerated liquid valve are all made of one-way valve, prevents residual sample reflux from producing
Raw pollution.
4) raffinate conveyance conduit is equipped with the first control valve, and third connecting pipe is equipped with the second control valve, wherein first
Control valve and the second control valve are all made of two-way valve, can guarantee to control the open and-shut mode of pipeline, to guarantee to test
And scale removal process is normally carried out.
5) it is fitted close setting rubber seal plug on the second small chamber outer wall on coupler, improves the leakproofness of coupler,
Simultaneously the convenience used can be improved convenient for docking with syringe needle.
6) position limiting structure is set by sample device, can guarantees that syringe needle is inserted into corresponding position after docking with coupler.
7) needle stand body bottom portion is equipped with butt joint, convenient for docking with SPR instrument flow path, guarantees that sample is fast and simple and is transported to
SPR instrument simultaneously realizes test.
8) coupler is docked with by sample device, and is cooperated by syringe needle and rubber seal plug, and letting out for sample is greatly reduced
It divulges a secret danger.
9) the unique flow path system of the tester makes fully functional stream while solving the problems, such as sample cross contamination
Road system bulk is substantially reduced, and reduces the power of power supply, realizes under battery electric power thus supplied there is enough continuous working periods;
The unique design by sample device and coupler, the feeding instrument test flow path for keeping tested sample reliable and easy, thus
It ensure that the realization of portable SPR instrument.
Detailed description of the invention
Fig. 1 is the overall structure diagram of the utility model;
Fig. 2 is the front shroud modular construction schematic diagram of the utility model;
Fig. 3 is the base plate part structural schematic diagram of the utility model;
Fig. 4 is the channel member structural schematic diagram of the utility model;
Fig. 5 is the channel member positive structure schematic of the utility model;
Fig. 6 is the base plate part schematic diagram of internal structure of the utility model;
Fig. 7 is the light path part structural schematic diagram of the utility model;
Fig. 8 is the sampler mounting structure schematic diagram of the utility model;
Fig. 9 is the utility model by sample device and coupler attachment structure schematic diagram;
Figure 10 is the structural schematic diagram by sample device of the utility model;
Figure 11 is the structural schematic diagram of the coupler of the utility model;
Figure 12 is the structural schematic diagram of the needle stand of the utility model;
Figure 13 is the flow path attachment structure schematic diagram of the utility model;
Figure 14 is the circuit connection schematic diagram of the utility model;
In figure: cover member before 1-, 2- base plate part, 21- control circuit board, 22- bottom plate, 23- buffer bottle, 24- regeneration
Liquid bottle, 25- waste liquid bottle, 26- panel components, 3- is by sample circle, and 31- is by sample device, and 3101- is by sample device ontology, the big chamber of 3102- first
Body, the small cavity of 3103- first, 32- needle stand, 3201- needle stand ontology, 3202- butt joint, 3203- syringe needle, 301- sample valve,
302- sample delivery pipeline, the second connecting pipe of 303-, 304- third connecting pipe, 305- raffinate conveyance conduit, 306- four-way
Pipe fitting, the first connecting pipe of 307-, 308- regenerated liquid conveyance conduit, 309- tee pipe fitting, 310- buffer conveyance conduit, 4- light
Circuit unit, the second cylindrical mirror of 402-, 401- cylinder-prism, 403- imaging lens, 404- camera, 405- biochip, 406-
Flow path features, 407- collimate camera lens, 408-LED light source, 409- collimating mirror, 410- optical filter and polarizing film, the first cylinder of 411-
Mirror, 5- touch control system, 6- identity card identification module, 7- channel member, 71- installing frame, the first control valve of 72-, 73- second
Control valve, 74- regenerated liquid valve, 75- buffer valve, 76- peristaltic pump, 8- battery, 9- sampler, 91- coupler, 9101- coupling
Clutch ontology, the second large cavity of 9102-, the small cavity of 9103- second.
Specific embodiment
Below in conjunction with Figure of description, the utility model is further described.
As represented in figures 1 through 14, a kind of portable SPR tester, including preceding cover member 1, base plate part 2, control circuit board
21, bottom plate 22, buffer bottle 23, regenerated liquid bottle 24, waste liquid bottle 25, panel components 26, by sample circle 3, by sample device 31, by sample device sheet
Body 3101, the first large cavity 3102, the first small cavity 3103, needle stand 32, needle stand ontology 3201, butt joint 3202, syringe needle 3203,
Sample valve 301, sample delivery pipeline 302, the second connecting pipe 303, third connecting pipe 304, raffinate conveyance conduit 305, four
Way pipe fitting 306, the first connecting pipe 307, regenerated liquid conveyance conduit 308, tee pipe fitting 309, buffer conveyance conduit 310, light
Circuit unit 4, the second cylindrical mirror 402, cylinder-prism 401, imaging lens 403, camera 404, biochip 405, flow path features
406, camera lens 407, LED light source 408, collimating mirror 409, optical filter and polarizing film 410, the first cylindrical mirror 411, touch control are collimated
System 5, identity card identification module 6, channel member 7, installing frame 71, the first control valve 72, the second control valve 73, regenerated liquid valve
74, buffer valve 75, peristaltic pump 76, battery 8, sampler 9, coupler 91, coupler ontology 9101, the second large cavity 9102
And the second small cavity 9103.
Sampler 9 is equipped on SPR tester, and SPR tester includes preceding cover member 1, is arranged in preceding cover member 1
On channel member 7, the light path part 4 that is arranged in preceding cover member 1 and the base plate part 2 being cooperatively connected with preceding cover member 1, bottom
Plate component 2 includes bottom plate 22 and the waste liquid bottle 25, regenerated liquid bottle 24, buffer bottle 23 and the control circuit board that are arranged on bottom plate 22
21, panel components 26 are additionally provided on base plate part 2, convenient for safeguarding to 22 equipment of bottom plate;Channel member 7 includes installing frame 71
And it is fixed at the peristaltic pump 76 in installing frame 71;It is equipped in preceding cover member 1 by sample circle 3, is equipped with by sample circle 3 by sample
Device 31,9 bottom of sampler are equipped with coupler 91, and the insertion of sampler 9 is by sample circle 3 and by coupler 91 and by sample device 31
It is cooperatively connected;Regenerated liquid bottle 24 is equipped with regenerated liquid conveyance conduit 308, and buffer bottle 23 is equipped with buffer conveyance conduit
310, position is equipped with tee pipe fitting 309 between 308 end of buffer conveyance conduit 310 and regenerated liquid conveyance conduit, and passes through three
Way pipe fitting 309 is connected, and for the connection setting of 302 one end of sample delivery pipeline by sample device 31, the other end is equipped with four-way pipe fitting 306, and
Setting raffinate conveyance conduit 305 is connected by four-way pipe fitting 306, first is equipped between tee pipe fitting 309 and four-way pipe fitting 306 and is connected
Adapter tube road 307, and be connected to by the first connecting pipe 307, it is additionally provided with the second connecting pipe 303 on four-way pipe fitting 306, and pass through
Second connecting pipe 303 is connected with the entrance of light path part 4, and the outlet of light path part 4 is equipped with third connecting pipe 304, third
Connecting pipe 304 is equipped with peristaltic pump 76, and peristaltic pump 76 is connected by pipeline with waste liquid bottle 25;On sample delivery pipeline 302 also
Equipped with pipeline connecting parts, and by pipeline connecting parts connect setting raffinate conveyance conduit 305,305 one end of raffinate conveyance conduit with
Pipeline connecting parts are connected, another to terminate in third connecting pipe 304 and between the second control valve 73 and peristaltic pump 76
Position at, residual liquid directly can be directly discharged into waste liquid bottle 25.
It is included by sample device ontology 3101 and being equipped in the needle stand 32 by 3101 bottom of sample device ontology, by sample by sample device 31
Device ontology 3101 includes the first large cavity 3102 and is arranged in 3102 bottom of the first large cavity and is connected to the first large cavity 3102
The first small cavity 3103;Coupler 91 includes coupler ontology 9101 and is equipped with rubber in 9101 bottom of coupler ontology
Glue blocking 33, coupler ontology 9101 include the second large cavity 9102 and setting 9102 bottom of the second large cavity and with it is second largest
The second small cavity 9103 that cavity 9102 is connected to;Needle stand 32 includes needle stand ontology 3201,3201 top of needle stand ontology is arranged in
Syringe needle 3203 and the butt joint 3202 that 32 body bottom portion of needle stand is arranged in are interconnected between syringe needle 3203 and butt joint 3202;
Second large cavity 9102 is equipped in the first large cavity 3102, and the second small cavity 9103 is arranged in the first small cavity 3103
It is interior, and be fitted close by rubber seal plug 33 and the first small cavity 3103;First large cavity 3102 and the first small cavity 3103 it
Between junction constitute position limiting structure, after the second large cavity 9102 is contacted with position limiting structure, syringe needle 3203 puncture rubber seal plug 33
And the corresponding position of the second small cavity 9103 is stretched to, so that coupler 91 is connected to by between sample device 31;Second is small
The outer wall of cavity 9103 is matched with rubber seal plug 33, and is sealed by rubber seal plug 33 to 91 bottom of coupler;Wherein
Needle stand 32 and by between 31 ontology of sample device use separate structure or integral structure.
Channel member 7 further include the buffer valve 75 being arranged in installing frame 71, regenerated liquid valve 74, the first control valve 72,
Second control valve 73 and sample valve 301, buffer valve 75 are arranged on buffer conveyance conduit 310, and the setting of regenerated liquid valve 74 exists
On regenerated liquid conveyance conduit 308, sample valve 301 is arranged on sample delivery pipeline 302, and the setting of the first control valve 72 is defeated in raffinate
It send on pipeline 305, the second control valve 73 is arranged in third connecting pipe 304, buffer valve 75, sample valve 301 and regenerated liquid
Valve 74 is all made of one-way valve, and the first control valve 72 and the second control valve 73 are all made of two-way valve, and each valve is corresponding for controlling
Pipeline, and cooperate control circuit board 21 carry out flow path control.
LED light source 408, collimation camera lens 407, optical filter and the polarization that light path part 4 includes frame, frame one end is arranged in
The second cylindrical mirror 402, collimating mirror 409 and the imaging lens 403 of the frame other end are arranged in piece 410 and the first cylindrical mirror 411,
The cylinder-prism 401 of position between being arranged in the frame, cylinder-prism 401 are equipped with biochip 405, set on biochip 405
There are flow path features 406,403 one end of imaging lens is equipped with camera 404.The entrance of light path part 4 and outlet are separately positioned on stream
406 both ends corresponding position of road component, tested sample and its relevant liquid are according to design sequence and require from chip
Pass through in runner, the light that the LED light source 408 of light path part 4 is sent out passes through optical filter and polarizing film after collimation camera lens 407 collimates
410 become the vertically light to vibration, accommodate to prism by cylindrical mirror 411, pass through cylindrical mirror again after prism surface total reflection
411 become directional light by collimating mirror 409 and imaging lens 403, finally image on the photosurface of camera 404.Photosurface
The signal processing of imaging is become into electric signal, the control system and program of instrument handle these signals, thus arrival pair
What sample was detected.
Preceding cover member 1 be equipped with touch control system 5 and identity card identification module 6, control circuit board 21 respectively with identity
Demonstrate,prove identification module 6, touch control system 5, peristaltic pump 76, buffer valve 75, regenerated liquid valve 74, the control of the first control valve 72, second
301 circuit connection of valve 73 processed and sample valve, light path part 4 and 5 circuit connection of touch control system, thus to entire tester
Flow path, data, display are controlled.
Working principle:
It first is sampled work with sampler 9 before test, by the coupler 91 of 9 bottom of sampler after the completion of sampling
Insertion is matched with by sample device 31 by sample circle 3, so that syringe needle 3203 is pierced through the rubber seal plug 33 of 91 bottom of coupler and is protruded into
To the corresponding position of the second small cavity 9103, the mating operation of sampler 9 and SPR tester is completed;Start SPR tester,
By 5 modulation control wiring board 21 of touch control system, receives signal and carry out data processing, control circuit board 21 is according to program
Design control flow path system work, SPR tester can also be powered by the power supply of battery 8 by external adapter;When test, the first control
Valve 72 processed is in normally off, and the second control valve 73 is in normally open, and sampler 9 passes through sample delivery pipeline 302, second
After connecting pipe 303, into the flow path features 406 of light path part 4, buffer and regenerated liquid pass through buffer delivery pipe respectively
Road 310 and regenerated liquid conveyance conduit 308 are after the first connecting pipe 307 and the second connecting pipe 303, into light path part 4
Flow path features in;Final sample, buffer, regenerated liquid pass through third connecting pipe 304 under the suction function of peristaltic pump 76
Into waste liquid bottle 25.
Cleaning process:
After the completion of sample test, sampler 9 is taken out, starts SPR tester, is modulated and is controlled by touch control system 5
Wiring board 21 processed receives signal and carries out data processing, and control circuit board 21 controls flow path system according to programming and works, clearly
When washing, the first control valve 72 is in normally open, and the second control valve 73 is in normally off, and sample delivery pipeline 302, first connects
Residual liquid in adapter tube road 307, the second connecting pipe 303, buffer conveyance conduit 310 and regenerated liquid conveyance conduit 308 exists
Pass through raffinate conveyance conduit 305 under the suction function of peristaltic pump 76, is directly discharged into waste liquid bottle 25.
The tester solves the problems, such as sample cross contamination by unique flow path designs, passes through unique sampling device
Design adapts to fast and convenient sample introduction requirement, while the runner design of succinct effective negative pressure hydrodynamic injection, and instrument is made to meet function
Portable design is realized while energy systematization, test automation and simplicity swift to operate, SPR instrument is made to can be used for scene
The basic demand of test, the identity card identification module of the tester can accurate check sample information, ensure that sample detection
The comparison consistency of process.
Claims (10)
1. a kind of portable SPR tester, which is characterized in that including SPR tester and be equipped with taking on SPR tester
Sampling device (9), the SPR tester include preceding cover member (1), the channel member (7) being arranged on preceding cover member (1), setting
Light path part (4) on preceding cover member (1) and the base plate part (2) with preceding cover member (1) mating connection, the base plate part
It (2) include bottom plate (22) and the waste liquid bottle (25) being arranged on bottom plate (22), regenerated liquid bottle (24), buffer bottle (23) and control
Wiring board (21);The channel member (7) includes installing frame (71) and the peristaltic pump (76) being fixed in installing frame (71);
It is equipped on the preceding cover member (1) by sample circle (3), it is described to be equipped with by sample circle (3) by sample device (31), the sampler
(9) bottom is equipped with coupler (91), and sampler (9) insertion is by sample circle (3) and by coupler (91) and by sample device
(31) it is cooperatively connected;The regenerated liquid bottle (24) is equipped with regenerated liquid conveyance conduit (308), on the buffer bottle (23)
It is described to be equipped with sample delivery pipeline (302) by sample device (31) equipped with buffer conveyance conduit (310), the regenerated liquid conveying
Pipeline (308), buffer conveyance conduit (310), sample delivery pipeline (302) are connected with the entrance of light path part (4) respectively, institute
The outlet for stating light path part (4) is equipped with third connecting pipe (304), and the third connecting pipe (304) is equipped with peristaltic pump
(76), the peristaltic pump (76) is connected by pipeline with waste liquid bottle (25);Pipeline is additionally provided on the sample delivery pipeline (302)
Connector, and by pipeline connecting parts connect setting raffinate conveyance conduit (305), described raffinate conveyance conduit (305) one end with
Pipeline connecting parts are connected, another to terminate on third connecting pipe (304).
2. a kind of portable SPR tester according to claim 1, which is characterized in that the buffer conveyance conduit
(310) position is equipped with tee pipe fitting (309) between regenerated liquid conveyance conduit (308) end, and passes through tee pipe fitting (309) phase
Connection, by sample device (31), the other end is equipped with four-way pipe fitting (306), and leads to for sample delivery pipeline (302) one end connection setting
Four-way pipe fitting (306) connection setting raffinate conveyance conduit (305) is crossed, between the tee pipe fitting (309) and four-way pipe fitting (306)
It is connected to equipped with the first connecting pipe (307), and by the first connecting pipe (307), the is additionally provided on the four-way pipe fitting (306)
Two connecting pipes (303), and be connected by the second connecting pipe (303) with the entrance of light path part (4).
3. a kind of portable SPR tester according to claim 1, which is characterized in that it is described by sample device (31) include by
It sample device ontology (3101) and is equipped in the needle stand (32) by sample device ontology (3101) bottom, it is described by sample device ontology (3101)
Including the first large cavity (3102) and setting the first large cavity (3102) bottom and be connected to the first large cavity (3102) the
One small cavity (3103);The coupler (91) includes coupler ontology (9101) and is equipped in coupler ontology (9101)
The rubber seal plug (33) of bottom, the coupler ontology (9101) include the second large cavity (9102) and are arranged in the second large cavity
(9102) bottom and the second small cavity (9103) being connected to the second large cavity (9102);The needle stand (32) includes needle stand ontology
(3201), syringe needle (3203) at the top of needle stand ontology (3201) and setting are set in the butt joint of needle stand (32) body bottom portion
(3202), it is interconnected between the syringe needle (3203) and butt joint (3202);Second large cavity (9102) is equipped with
In the first large cavity (3102), second small cavity (9103) setting passes through rubber in the first small cavity (3103)
Blocking (33) is fitted close with the first small cavity (3103).
4. a kind of portable SPR tester according to claim 1, which is characterized in that the channel member (7) further includes
The buffer valve (75) that is arranged in installing frame (71), regenerated liquid valve (74), the first control valve (72), the second control valve (73) and
Sample valve (301), the buffer valve (75) are arranged on buffer conveyance conduit (310), and regenerated liquid valve (74) is arranged again
On raw liquid conveyance conduit (308), the sample valve (301) is arranged on sample delivery pipeline (302), first control valve
(72) it is arranged on raffinate conveyance conduit (305), second control valve (73) is arranged on third connecting pipe (304), institute
It states buffer valve (75), sample valve (301) and regenerated liquid valve (74) and is all made of one-way valve, first control valve (72) and
Two control valves (73) are all made of two-way valve.
5. a kind of portable SPR tester according to claim 1, which is characterized in that the raffinate conveyance conduit (305)
It connects on third connecting pipe (304) and at the position between the second control valve (73) and peristaltic pump (76).
6. a kind of portable SPR tester according to claim 1, which is characterized in that the light path part (4) includes frame
Frame, LED light source (408), collimation camera lens (407), optical filter and polarizing film (410), the first cylindrical mirror (411), the second cylindrical mirror
(402), collimating mirror (409), imaging lens (403) and cylinder-prism (401), the LED light source (408), collimation camera lens
(407), a side position of frame, second cylindrical mirror is arranged in optical filter and polarizing film (410) and the first cylindrical mirror (411)
(402), another side position of frame, cylinder-prism (401) setting is arranged in collimating mirror (409) and imaging lens (403)
Between in the frame at position, the cylinder-prism (401) is equipped with biochip (405), and the biochip (405) is equipped with
Flow path features (406), described imaging lens (403) one end be equipped with camera (404), the entrance of the light path part (4) and go out
Mouth is separately positioned on flow path features (406) both ends corresponding position.
7. a kind of portable SPR tester according to claim 4, which is characterized in that the preceding cover member (1) is equipped with
Touch control system (5) and identity card identification module (6), the control circuit board (21) respectively with identity card identification module (6),
Touch control system (5), light path part (4), peristaltic pump (76), buffer valve (75), regenerated liquid valve (74), the first control valve
(72), the second control valve (73) and sample valve (301) circuit connection.
8. a kind of portable SPR tester according to claim 3, which is characterized in that first large cavity (3102)
Junction between the first small cavity (3103) constitutes position limiting structure, and second large cavity (9102) contacts with position limiting structure
Afterwards, syringe needle (3203) pierces through rubber seal plug (33) and stretches to the corresponding position of the second small cavity (9103).
9. a kind of portable SPR tester according to claim 3, which is characterized in that the second small cavity (9103)
Outer wall matched with rubber seal plug (33), and coupler (91) bottom is sealed by rubber seal plug (33).
10. a kind of portable SPR tester according to claim 3, which is characterized in that the needle stand (32) with by sample device
(31) separate structure or integral structure are used between ontology.
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CN201820634684.4U CN208224090U (en) | 2018-04-30 | 2018-04-30 | A kind of portable SPR tester |
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CN201820634684.4U CN208224090U (en) | 2018-04-30 | 2018-04-30 | A kind of portable SPR tester |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN108827919A (en) * | 2018-04-30 | 2018-11-16 | 浙江诺迦生物科技有限公司 | A kind of portable SPR tester |
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Publication number | Priority date | Publication date | Assignee | Title |
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CN108827919A (en) * | 2018-04-30 | 2018-11-16 | 浙江诺迦生物科技有限公司 | A kind of portable SPR tester |
CN108827919B (en) * | 2018-04-30 | 2024-04-16 | 浙江诺迦生物科技有限公司 | Portable SPR tester |
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