CN103712902A - Hematology analyzer adopting single negative pressure source and pipeline flow regulator - Google Patents

Hematology analyzer adopting single negative pressure source and pipeline flow regulator Download PDF

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Publication number
CN103712902A
CN103712902A CN201310748922.6A CN201310748922A CN103712902A CN 103712902 A CN103712902 A CN 103712902A CN 201310748922 A CN201310748922 A CN 201310748922A CN 103712902 A CN103712902 A CN 103712902A
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pipeline
solenoid valve
negative pressure
flow regulator
colorimetric pool
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CN201310748922.6A
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CN103712902B (en
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于春江
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General Hospital of Angang Group Company (Angang Emergency Center)
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Angang Steel Co Ltd
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Abstract

The invention belongs to the technical field of medical treatment detection equipment, and particularly relates to a hematology analyzer adopting a single negative pressure source and a pipeline flow regulator. The hematology analyzer comprises a diluent container, a hemolytic agent container, a cleaning agent container, a cleaning pond, a hollow blood sample taking needle, a needle transferring device, a photoelectric colorimetry device, a No.1 diluting colorimetric pond, a No. 2 diluting pond, a metering and measuring device, a waste liquid bottle, a constant pressure device and a negative pressure pump connected with the constant pressure device. The hematology analyzer is characterized in that the constant pressure device and the negative pressure pump are of one group to form the single negative pressure source, all devices are connected with one another through pipelines, and an electronic valve and a flow regulator are arranged on the pipeline. According to the hematology analyzer provided by the invention, the single negative pressure source is matched with a corresponding quantitative pipeline device, so that works that a blood sample, a testing reagent and waste liquid in processes of sampling, reagent injecting, uniform-mixing, detecting, discharging and the like of the hematology analyzer enter specific positions through specified channels according to specified dosage in sequence, and the like are completed, and thus an accurate detection result is ensured.

Description

Adopt the cellanalyzer of single negative pressure source and pipeline flow regulator
Technical field
The invention belongs to clinical medicine inspection machine technical field, especially relate to a kind of cellanalyzer that adopts single negative pressure source and pipeline flow regulator.
Background technology
In modern clinic laboratory medicine field, Blood routine examination is one of the most basic, most important inspection item.The object of this inspection is to understand the data such as the quantity of various cells and important component in blood, form, ratio, makes the important evidence of diagnosis as clinician.
Existing Blood routine examination mainly adopts---machine method, both first by machine automatically or semi-automatically to tested blood sample carry out quantitatively, the operation such as dilution, dyeing, adopt again the technological means such as Coulter principle (electrical impedance method), photoelectric colorimetry principle, laser diffraction principle, sheath stream technology to count and computing, and output detections result.The processes such as the equipment such as existing full-automatic blood counting instrument or cellanalyzer (as three sorting devices and five sorting devices) inject, mix at sampling, reagent, detection, discharge opeing, generally adopt the labyrinths such as many negative pressure sources, multi-syringe (ram pump), proportioning device to complete above-mentioned functions, cause the problems such as device structure is complicated, manufacturing cost is high, fault is various, difficult in maintenance.
In cellanalyzer equipment in the past, due to the multiple negative pressure of needs or malleation, thereby be provided with a plurality of negative pressure sources or positive pressure source.For realizing this function, some equipment is provided with a plurality of negative pressure pumps, and some equipment is provided with a plurality of syringes (ram pump), or both use simultaneously.Its problem is:
1, negative pressure pump and supporting feeding pressure stabilizing device manufacturing cost thereof are higher, and there are certain requirements safeguarding.
2, the sealing problem of syringe (ram pump) is to affect the normal key factor of using of equipment, easily leaks gas, leakage fault.
Meanwhile, in cellanalyzer in the past, for realizing quantitative function, adopt the structures such as mercury manometr proportioning device, Photoelectric Detection proportioning device, syringe (ram pump) stroke quantitative device, bubble proportioning device more.Its problem is:
1, the problem of mercury manometr proportioning device is that mercury is poisonous, easily pollutes, and volatile, precision is low, Maintenance Difficulty.
2, the problem of Photoelectric Detection proportioning device is that manufacturing cost is high, and the work load of heavy system computing machine, when many pipelines have liquid flow simultaneously, is difficult to detect and control especially.
3, the sealing problem of syringe (ram pump) stroke quantitative device causes gas leakage, leakage fault are phenomenons occurred frequently, directly affect the accuracy of testing result.
4, the manufacturing cost of bubble proportioning device also will increase pressure-releasing electromagnetic valve on the basis of Photoelectric Detection proportioning device, has all problems of Photoelectric Detection proportioning device, and precision is not high.
Comprehensive said structure forms and detection mode, makes equipment Inspection low precision, complex structure, and manufacturing cost increases, and easily sends out fault, maintenance and repair difficulty.
Summary of the invention
The object of this invention is to provide a kind of cellanalyzer that adopts single negative pressure source and pipeline flow regulator, can solve the processes such as existing cellanalyzer injects, mixes at sampling, reagent, detection, discharge opeing, because of problems such as complex structure, the manufacturing cost that adopts the labyrinths such as many negative pressure sources, multi-syringe (ram pump), traditional proportioning device to cause are high, fault is various, difficult in maintenance.
The object of the invention is to realize by following technical proposals:
A kind of cellanalyzer that adopts single negative pressure source and pipeline flow regulator of the present invention, comprise diluent container, hemolytic agent container, detergent container, service sink, hollow blood specimen collection pin, hollow blood specimen collection pin is connected therewith moves needle device, photoelectric colorimetry device, 1# dilutes colorimetric pool, 2# diluting tank, the count measurement device that 2# diluting tank communicates therewith, waste liquid bottle, constant-voltage equipment, the negative pressure pump that constant-voltage equipment is connected therewith, it is characterized in that described constant-voltage equipment and negative pressure pump are one group, form single negative pressure source, described diluent container is connected with described 1# dilution colorimetric pool by 1# pipeline, described hemolytic agent container is connected with described 1# dilution colorimetric pool by 2# pipeline, described detergent container is connected with described 1# dilution colorimetric pool by 3# pipeline, the described needle device that moves is connected with described 1# dilution colorimetric pool by 4# pipeline,
Described diluent container is connected with described 2# diluting tank by 5# pipeline, described detergent container is connected with described 2# diluting tank by 6# pipeline, described 1# dilution colorimetric pool is connected by 7# pipeline with 2# diluting tank, described 1# dilution colorimetric pool is also connected by 9# pipeline with 2# diluting tank, and 9# pipeline is connected with 10# negative pressure pump main pipeline
Described 1# dilution colorimetric pool is provided with 8# pipeline, and this 8# pipeline is connected with extraneous air, described 2# diluting tank is provided with 11# pipeline, and this 11# pipeline is connected with extraneous air, described 1# dilution colorimetric pool is connected with described waste liquid bottle by 12# pipeline, described 2# diluting tank is connected with described waste liquid bottle by 14# pipeline, described count measurement device is connected with described waste liquid bottle by 15# pipeline, described waste liquid bottle is connected with described 10# negative pressure pump main pipeline by 13# pipeline
Described 1# pipeline is provided with 1# solenoid valve and 1# flow regulator, described 2# pipeline is provided with 2# solenoid valve and 2# flow regulator, described 3# pipeline is provided with 3# solenoid valve and 3# flow regulator, described 4# pipeline is provided with 4# solenoid valve and 4# flow regulator, described 5# pipeline is provided with 5# solenoid valve and 5# flow regulator, described 6# pipeline is provided with 6# solenoid valve and 6# flow regulator, described 7# pipeline is provided with 7# solenoid valve and 7# flow regulator, described 8# pipeline is provided with 8# solenoid valve, described 9# pipeline is being provided with 9# solenoid valve near 1# dilution colorimetric pool end, and be provided with 10# solenoid valve near 2# diluting tank end, described 11# pipeline is provided with 11# solenoid valve, described 12# pipeline is provided with 12# solenoid valve, described 13# pipeline is provided with 13# solenoid valve, described 14# pipeline is provided with 14# solenoid valve, described 15# pipeline is provided with 15# solenoid valve.
Described 1#-15# pipe material is glass, metal, silica gel, rubber or plastics.
Described 1#-7# flow regulator is butterfly valve, ball valve, plunger or tapered pipeline.
Advantage of the present invention:
(1) cellanalyzer of the present invention adopts single negative pressure source to coordinate corresponding quantity tube duct device, complete cellanalyzer in sampling, reagent injects, mix, detect, blood sample in the processes such as discharge opeing, testing reagent and waste liquid in accordance with regulations dosage, regulation order enter the work such as assigned position by regulation passage, accurate to guarantee testing result.
(2) cellanalyzer of the present invention has been cancelled traditional many negative pressure sources and multi-syringe (ram pump) structure, adopts a set of negative pressure pump and constant-voltage equipment to provide single negative pressure source to meet the demand of whole system.
(3) cellanalyzer of the present invention has been cancelled baroque proportioning device, adopts simple flow regulator to control the passage section area of pipeline, by pipeline, quantitatively completes quantitative function.
Accompanying drawing explanation
Fig. 1 is structural representation of the present invention.
Embodiment
Below in conjunction with accompanying drawing, further illustrate the specific embodiment of the present invention.
As shown in Figure 1, a kind of cellanalyzer that adopts single negative pressure source and pipeline flow regulator of the present invention, comprise diluent container, hemolytic agent container, detergent container, service sink, hollow blood specimen collection pin, hollow blood specimen collection pin is connected therewith moves needle device, photoelectric colorimetry device, 1# dilutes colorimetric pool, 2# diluting tank, the count measurement device that 2# diluting tank communicates therewith, waste liquid bottle, constant-voltage equipment, the negative pressure pump that constant-voltage equipment is connected therewith, it is characterized in that described constant-voltage equipment and negative pressure pump are one group, form single negative pressure source, described diluent container is connected with described 1# dilution colorimetric pool by 1# pipeline, described hemolytic agent container is connected with described 1# dilution colorimetric pool by 2# pipeline, described detergent container is connected with described 1# dilution colorimetric pool by 3# pipeline, the described needle device that moves is connected with described 1# dilution colorimetric pool by 4# pipeline,
Described diluent container is connected with described 2# diluting tank by 5# pipeline, described detergent container is connected with described 2# diluting tank by 6# pipeline, described 1# dilution colorimetric pool is connected by 7# pipeline with 2# diluting tank, described 1# dilution colorimetric pool is also connected by 9# pipeline with 2# diluting tank, and 9# pipeline is connected with 10# negative pressure pump main pipeline
Described 1# dilution colorimetric pool is provided with 8# pipeline, and this 8# pipeline is connected with extraneous air, described 2# diluting tank is provided with 11# pipeline, and this 11# pipeline is connected with extraneous air, described 1# dilution colorimetric pool is connected with described waste liquid bottle by 12# pipeline, described 2# diluting tank is connected with described waste liquid bottle by 14# pipeline, described count measurement device is connected with described waste liquid bottle by 15# pipeline, described waste liquid bottle is connected with described 10# negative pressure pump main pipeline by 13# pipeline
Described 1# pipeline is provided with 1# solenoid valve and 1# flow regulator, described 2# pipeline is provided with 2# solenoid valve and 2# flow regulator, described 3# pipeline is provided with 3# solenoid valve and 3# flow regulator, described 4# pipeline is provided with 4# solenoid valve and 4# flow regulator, described 5# pipeline is provided with 5# solenoid valve and 5# flow regulator, described 6# pipeline is provided with 6# solenoid valve and 6# flow regulator, described 7# pipeline is provided with 7# solenoid valve and 7# flow regulator, described 8# pipeline is provided with 8# solenoid valve, described 9# pipeline is being provided with 9# solenoid valve near 1# dilution colorimetric pool end, and be provided with 10# solenoid valve near 2# diluting tank end, described 11# pipeline is provided with 11# solenoid valve, described 12# pipeline is provided with 12# solenoid valve, described 13# pipeline is provided with 13# solenoid valve, described 14# pipeline is provided with 14# solenoid valve, described 15# pipeline is provided with 15# solenoid valve.
Described 1#-15# pipe material is glass, metal, silica gel, rubber or plastics.
Described 1#-7# flow regulator is butterfly valve, ball valve, plunger or tapered pipeline, wherein tapered pipeline can be according to ad-hoc location the particular requirement to device for cleaning pipeline flow area, produce in advance satisfactory pipeline, and be installed on corresponding position; When pipe material is the flexible materials such as rubber, plastics, also can on pipeline, install and can make flexible duct produce the apparatus of mechanically deform by fashion of extrusion, thereby reach change cross-sectional flow area, realize the object of pipeline reducing diameter.
In pipeline, the flow velocity of liquid is determined by the sectional area of the pressure in pipeline, pipeline and the viscosity of liquid, and flow is determined by the product of flow velocity and currency.For specific pipeline, after the viscosity of liquid, the pressure in pipeline, currency and flow are determined in pipeline, as long as regulate the sectional area of pipeline to appropriate value, can obtain the liquid of prescribed dose.
In the present invention, be to adopt this principle, at all needs, provide on the pipeline of determining dosage particular liquid solenoid valve and pipeline flow regulator are installed.By system program, controlled the make-and-break time of each solenoid valve, by pipeline flow regulator, preset the cross-sectional flow area of pipeline, under the single suction function providing in system, each pipeline can provide the blood sample, reagent of given dose etc. to 1# dilution colorimetric pool and 2# diluting tank to finish the work.
As shown in drawings, a set-up procedure can be carried out in the following order:
1, close solenoid valve used;
2, negative pressure pump starts to constant-voltage equipment can provide definite negative pressure;
3, move needle device hollow blood specimen collection pin is moved to service sink;
4, open 1#, 2#, 3#, 4# and 9# solenoid valve, at the appointed time the dilution of prescribed dose, hemolytic agent, clean-out system are sucked to 1# dilution colorimetric pool, close 1#, 2#, 3#, 4# and 9# solenoid valve;
5, open 8#, 12# and 13# solenoid valve, the mixing material that 1# is diluted to colorimetric pool sucks waste liquid bottle, closes 8#, 12# and 13# solenoid valve;
6, open 3#, 6#, 9# and 10# solenoid valve, at the appointed time the clean-out system of prescribed dose is sucked to 1# dilution colorimetric pool and 2# diluting tank, close 3# and 6# solenoid valve;
7, open 8# and 11# solenoid valve, air amount produces bubble in 1# dilution colorimetric pool and 2# diluting tank, with abundant stirring and washing agent, reaches cleaning object;
8, after the stipulated time, close 9# and 10# solenoid valve, open 12#, 13#, 14# and 15# solenoid valve, the liquid in 1# dilution colorimetric pool, 2# diluting tank and the super measurement mechanism of counting sucks waste liquid bottle, closes above-mentioned solenoid valve used.
As shown in drawings, a testing process can be carried out in the following order:
1, open 1# and 9# solenoid valve, at the appointed time the dilution of prescribed dose is sucked to 1# dilution colorimetric pool, close 1# solenoid valve;
2, move needle device sampling needle is moved in heparin tube, open 4# solenoid valve, at the appointed time the blood sample to be measured of prescribed dose is sucked to 1# dilution colorimetric pool, close 4# solenoid valve;
3, open 8# solenoid valve, air amount produces bubble in 1# dilution colorimetric pool, fully to mix the 1# haemocyte suspension that forms regulation dilution ratio, closes 9# solenoid valve;
4, open 7# and 10# solenoid valve, at the appointed time the 1# haemocyte suspension of prescribed dose is sucked in 2# diluting tank from 1# dilution colorimetric pool, close 7# and 8# solenoid valve;
5, open 5# solenoid valve, at the appointed time the dilution of prescribed dose is sucked in 2# diluting tank, close 5# solenoid valve;
6, open 11# solenoid valve, air amount produces bubble in 2# diluting tank, fully to mix the 2# haemocyte suspension that forms regulation dilution ratio, closes 10# solenoid valve;
7, open 13# and 15# solenoid valve, the 2# haemocyte suspension that makes at the appointed time prescribed dose enters waste liquid bottle after by count measurement device, detects and calculate leucocyte, red blood cell and hematoblastic quantity, closes 15# solenoid valve;
8, open 14# solenoid valve, the liquid in 2# diluting tank is sucked to waste liquid bottle, close 11#, 13# and 14# solenoid valve;
9, open 6# and 10# solenoid valve, make at the appointed time the clean-out system of prescribed dose suck in 2# diluting tank, close 6# solenoid valve;
10, open 11# solenoid valve, air amount produces bubble in 2# diluting tank, with abundant stirring and washing agent, reaches cleaning object, closes 10# solenoid valve;
11, open 14# and 15# solenoid valve, the liquid in 2# diluting tank and count measurement device is sucked to waste liquid bottle, close 11#, 13#, 14# and 15# solenoid valve;
12, open 2# and 9# solenoid valve, make at the appointed time the hemolytic agent of prescribed dose suck 1# dilution colorimetric pool, close 2# solenoid valve;
13, open 8# solenoid valve, air amount produces bubble in 1# dilution colorimetric pool, fully to mix, destroys haemocyte film, forms 3# haemocyte suspension, closes 9# solenoid valve;
14, start photoelectric colorimetry device, measure the hemoglobin concentration of 3# haemocyte suspension in 1# dilution colorimetric pool, close photoelectric colorimetry device;
15, open 7# and 10# solenoid valve, at the appointed time the 3# haemocyte suspension of prescribed dose is sucked in 2# diluting tank from 1# dilution colorimetric pool, close 7# and 8# solenoid valve;
16, open 5# solenoid valve, at the appointed time the dilution of prescribed dose is sucked in 2# diluting tank, close 5# solenoid valve;
17, open 11# solenoid valve, air amount produces bubble in 2# diluting tank, fully to mix the 4# haemocyte suspension that forms regulation dilution ratio, closes 10# solenoid valve;
18, open 13# and 15# solenoid valve, the 4# haemocyte suspension that makes at the appointed time prescribed dose enters waste liquid bottle after by count measurement device, detects and calculate lymphocyte, neutrophil leucocyte and monocytic quantity, closes 15# solenoid valve;
19, open 14# solenoid valve, the liquid in 2# diluting tank is sucked to waste liquid bottle, close 11#, 13# and 14# solenoid valve;
20, move needle device hollow blood specimen collection pin is moved to service sink;
21, open 3#, 4#, 6#, 9# and 10# solenoid valve, at the appointed time the clean-out system of prescribed dose is sucked to 1# dilution colorimetric pool and 2# diluting tank, close 3#, 4# and 6# solenoid valve;
22, open 8# and 11# solenoid valve, air amount produces bubble in 1# dilution colorimetric pool and 2# diluting tank, with abundant stirring and washing agent, reaches cleaning object;
23, after the stipulated time, close 9# and 10# solenoid valve, open 12#, 13#, 14# and 15# solenoid valve, the liquid that 1# is diluted in colorimetric pool, 2# diluting tank and count measurement device sucks waste liquid bottle, closes above-mentioned solenoid valve used.
Cellanalyzer of the present invention adopts single negative pressure source to coordinate corresponding quantity tube duct device, complete cellanalyzer in sampling, reagent injects, mix, detect, blood sample in the processes such as discharge opeing, testing reagent and waste liquid in accordance with regulations dosage, regulation order enter the work such as assigned position by regulation passage, accurate to guarantee testing result.The present invention adopts a set of negative pressure pump and constant-voltage equipment can provide single negative pressure source to meet the demand of whole system, and cancelled baroque proportioning device, adopt simple flow regulator to control the passage section area of pipeline, by pipeline, quantitatively can complete quantitative function.

Claims (3)

1. a cellanalyzer that adopts single negative pressure source and pipeline flow regulator, comprise diluent container, hemolytic agent container, detergent container, service sink, hollow blood specimen collection pin, hollow blood specimen collection pin is connected therewith moves needle device, photoelectric colorimetry device, 1# dilutes colorimetric pool, 2# diluting tank, the count measurement device that 2# diluting tank communicates therewith, waste liquid bottle, constant-voltage equipment, the negative pressure pump that constant-voltage equipment is connected therewith, it is characterized in that described constant-voltage equipment and negative pressure pump are one group, form single negative pressure source, described diluent container is connected with described 1# dilution colorimetric pool by 1# pipeline, described hemolytic agent container is connected with described 1# dilution colorimetric pool by 2# pipeline, described detergent container is connected with described 1# dilution colorimetric pool by 3# pipeline, the described needle device that moves is connected with described 1# dilution colorimetric pool by 4# pipeline,
Described diluent container is connected with described 2# diluting tank by 5# pipeline, described detergent container is connected with described 2# diluting tank by 6# pipeline, described 1# dilution colorimetric pool is connected by 7# pipeline with 2# diluting tank, described 1# dilution colorimetric pool is also connected by 9# pipeline with 2# diluting tank, and 9# pipeline is connected with 10# negative pressure pump main pipeline
Described 1# dilution colorimetric pool is provided with 8# pipeline, and this 8# pipeline is connected with extraneous air, described 2# diluting tank is provided with 11# pipeline, and this 11# pipeline is connected with extraneous air, described 1# dilution colorimetric pool is connected with described waste liquid bottle by 12# pipeline, described 2# diluting tank is connected with described waste liquid bottle by 14# pipeline, described count measurement device is connected with described waste liquid bottle by 15# pipeline, described waste liquid bottle is connected with described 10# negative pressure pump main pipeline by 13# pipeline
Described 1# pipeline is provided with 1# solenoid valve and 1# flow regulator, described 2# pipeline is provided with 2# solenoid valve and 2# flow regulator, described 3# pipeline is provided with 3# solenoid valve and 3# flow regulator, described 4# pipeline is provided with 4# solenoid valve and 4# flow regulator, described 5# pipeline is provided with 5# solenoid valve and 5# flow regulator, described 6# pipeline is provided with 6# solenoid valve and 6# flow regulator, described 7# pipeline is provided with 7# solenoid valve and 7# flow regulator, described 8# pipeline is provided with 8# solenoid valve, described 9# pipeline is being provided with 9# solenoid valve near 1# dilution colorimetric pool end, and be provided with 10# solenoid valve near 2# diluting tank end, described 11# pipeline is provided with 11# solenoid valve, described 12# pipeline is provided with 12# solenoid valve, described 13# pipeline is provided with 13# solenoid valve, described 14# pipeline is provided with 14# solenoid valve, described 15# pipeline is provided with 15# solenoid valve.
2. the cellanalyzer of the single negative pressure source of employing according to claim 1 and pipeline flow regulator, is characterized in that described 1#-15# pipe material is glass, metal, silica gel, rubber or plastics.
3. the cellanalyzer of the single negative pressure source of employing according to claim 1 and pipeline flow regulator, is characterized in that described 1#-7# flow regulator is butterfly valve, ball valve, plunger or tapered pipeline.
CN201310748922.6A 2013-12-31 2013-12-31 Adopt the cellanalyzer of single negative pressure source and pipeline flow regulator Active CN103712902B (en)

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