CN208206990U - Reaction cup sample introduction mechanism - Google Patents

Reaction cup sample introduction mechanism Download PDF

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Publication number
CN208206990U
CN208206990U CN201820784913.0U CN201820784913U CN208206990U CN 208206990 U CN208206990 U CN 208206990U CN 201820784913 U CN201820784913 U CN 201820784913U CN 208206990 U CN208206990 U CN 208206990U
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reaction cup
box
sample introduction
sample
reaction
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CN201820784913.0U
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Chinese (zh)
Inventor
许行尚
杰弗瑞·陈
赵大强
应家树
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Nanjing Lanyu Biological Technology Co Ltd
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Nanjing Lanyu Biological Technology Co Ltd
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Abstract

The utility model discloses a kind of reaction cup sample introduction mechanisms, distribute reaction cup box along the longitudinal, and reaction cup box is mounted on the base by sample introduction bracket;Reaction cup is assemblied in reaction cup packaging consumptive material, is pushed into reaction cup box;One end of the reaction cup sample introduction mechanism is additionally provided with sample introduction motor, and sample introduction motor has synchronous pulley, is additionally provided with the idle pulley matched with synchronous pulley;The synchronous belt being wrapped on synchronous pulley and idle pulley, that section being located above are placed in reaction cup box, that underlying section is placed in the outside of reaction cup box;Reaction cup push plate is additionally provided on synchronous belt.Distribute reaction cup box along the longitudinal, compact-sized, area occupied is small;Reaction cup is assemblied in reaction cup packaging consumptive material, it is therefore prevented that pollution;That section that synchronous belt is located above is placed in the reaction cup box, that underlying section is placed in the outside of reaction cup box, in this way, allowing reaction cup push plate will be in reaction cup packaging consumptive material push-in reaction cup box.

Description

Reaction cup sample introduction mechanism
Technical field
The utility model belongs to technical field of medical equipment, examines more particularly, to one kind for automatically extracting amplifier molecule The reaction cup sample introduction mechanism of disconnected device.
Background technique
When carrying out molecular diagnosis, most of molecular diagnosises are all semi-automated instruments currently on the market, need to carry out artificial It is put into the nucleic acid step extracted, quantitative analysis is being carried out by instrument, so that increasing the generated test of manual intervention Error, test speed is slow, is manually placed into the nucleic acid extracted and be easy to cause biological pollution, and examines automatically extracting amplifier molecule In disconnected equipment, instrument internal, which mutually pollutes, is the largest difficult point.
In Chinese patent literature CN103399161B, a kind of portable automatic chemiluminescence immunoassay system is disclosed System, wherein reaction cup pushing meanss include two groups of push rods for the movement of driving a reaction cup, for controlling two groups of push rod water respectively Translation dynamic the first control mechanism and the second control mechanism, for guiding the first straight line guide rail of two groups of push rod mobile guides respectively With second straight line guide rail, be provided with sliding block in first, second linear guide, two groups of push rods respectively with corresponding sliding block phase Connection, two groups of push rods include support arm and for pushing away the pushing block for holding reaction cup, and the pushing block is arranged on support arm And the pushing block of two groups of push rods is in same level and motion path is parallel.
But the reaction cup pushing meanss in above-mentioned technical proposal are less desirable in the specific use process, and area occupied is too Greatly, the equipment for being not suitable for modularization setting, it is inconvenient used in the full-automatic amplifier molecule diagnostic device that extracts, and anti-pollution ability It is weak.
Utility model content
The technical problem to be solved by the present invention is to provide it is a kind of it is compact-sized, area occupied is small, antipollution reaction Cup sample introduction mechanism.
In order to solve the above technical problems, the technical solution adopted in the utility model is, the reaction cup sample introduction mechanism is along longitudinal direction Reaction cup box is distributed with, the reaction cup box is mounted on the base by sample introduction bracket;Reaction cup is assemblied in reaction cup packaging consumption In material, it is pushed into the reaction cup box;One end of the reaction cup sample introduction mechanism is additionally provided with sample introduction motor, the sample introduction motor tool There is synchronous pulley, in the other end of the reaction cup sample introduction mechanism, is additionally provided with the idle pulley matched with the synchronous pulley;It twines The synchronous belt being wound on the synchronous pulley and the idle pulley, that section being located above are placed in the reaction cup box, are located at That section of lower section is placed in the outside of the reaction cup box;Reaction cup push plate is additionally provided on the synchronous belt.
By adopting the above technical scheme, reaction cup box is distributed along the longitudinal, so that reaction cup sample introduction mechanism overall structure is by anti- A glass box elongated shape limitation is answered, compact-sized, area occupied is small;Reaction cup is assemblied in reaction cup packaging consumptive material, described in push-in In reaction cup box, it is therefore prevented that pollution;That section that synchronous belt is located above is placed in the reaction cup box, it is underlying that Section is placed in the outside of the reaction cup box, in this way, allowing reaction cup push plate that reaction cup packaging consumptive material is pushed into the reaction In cup box;The reaction cup sample introduction mechanism of above structure, high degree of automation are matched with the full-automatic amplifier molecule diagnostic device that extracts Dress, work efficiency is high.
Further improve is that the sample introduction bracket is made of four cylinders, and four cylinders are mounted on reaction cup The bottom of box;Reaction cup packaging consumption material box is additionally provided in the reaction cup box, the reaction cup packaging consumptive material is placed on institute It states in reaction cup packaging consumption material box.
Reaction cup is set and packs consumption material box, so that consumptive material does not contact directly with reaction cup box, synchronous belt is in reaction cup It packs between consumption material box and the bottom interior wall of reaction cup box, it is not direct to be contacted with reaction cup packaging consumptive material, prevent pollution problem; Reaction cup packs consumptive material push-in and movement is more regular.
Further improve is, in one end of the reaction cup box, and is located above the sample introduction motor and is provided with one Notch;The other end of reaction cup box of the notch is provided with as input end;Being arranged at position jaggy can be used for adding Optoelectronic switch, can detecte whether reaction cup packaging consumptive material is put into position.
Further improve is that the end of the reaction cup packaging consumption material box is provided with leader, facilitates operation, will be anti- Cup packaging consumption material box is answered to haul out.
Further improve is that the cross section of the reaction cup box is rectangle;The reaction cup packaging consumption material box Top is opening.
Further improve is that the sample introduction motor is stepper motor.
The invention solves another technical problem be to provide it is a kind of do not need to carry out being manually placed into the nucleic acid extracted, Measuring accuracy is high, and the full-automatic extraction amplifier molecule diagnostic device that the testing time is short.
In order to solve the above technical problems, the technical solution adopted in the utility model is, which is examined Disconnected all-in-one machine includes the bracket of pedestal and setting on the base, further includes having:
Nucleic acid extraction module is used for purifying nucleic acid, and the nucleic acid extraction module is provided with reaction platform, and reaction cup is placed In the reaction platform;
Sample access mechanism, for saving sample, the sample access mechanism is located at the side of the nucleic acid extraction module And be placed on the pedestal, the sample access mechanism is provided with sample rack;
Mechanical arm mechanism, has Y-axis horizontal box, and the vertical cabinet of Z axis does Y-axis horizontal movement along the Y-axis horizontal box; Sampling head moves up and down on the vertical cabinet of the Z axis;The Y-axis horizontal box is connected with the bracket;
Hardware installation module, for installing hardware, the hardware installation module setting the Y-axis horizontal box with it is described Bracket is connected the lower section at position;
PCR module, for detecting sample, the PCR module setting is in hardware installation module side and is located at described Below bracket;
Biohazard Waste containing box includes to be arranged in the sample access mechanism and institute for storing Biohazard Waste The containing box between PCR module is stated, and is installed on the pedestal;
The top of the Biohazard Waste containing box is arranged in for storing reagent in reagent storing mechanism;
Reaction cup sample introduction mechanism is arranged in the front end of the nucleic acid extraction module, and is located on the pedestal.
By adopting the above technical scheme, all parts are incorporated on pedestal and form complete equipment, structure-integrated, flowing water Change operation, the testing time is short, and using effect is good, and reaction cup is pushed into nucleic acid extraction module by reaction cup sample introduction mechanism, Using mechanical arm mechanism from being sampled in the reaction cup being originally added in reaction cup packaging consumptive material in sample access mechanism, reaction terminates Afterwards, nucleic acid is extracted by mechanical arm mechanism into the EP pipe of reagent storing mechanism, and reaction cup waste is focused on to medical waste In object containing box;EP pipe equipped with reagent is extracted to PCR module from reagent storing mechanism expand again by mechanical arm mechanism Detection;Integral module is designed using enclosed modulesization, has prevented equipment pollution problem caused by due to nucleic acid extraction;Using machine Tool arm mechanism transfer nucleic acid, has prevented the influence to be influenced each other because of intermodule for detection data;Hardware installation module will own Circuit board is integrated within hardware module, has prevented external electromagnetic interference problem, to prevent to make because of electromagnetic interference At data fluctuations, measuring accuracy is high.
Further improve be, the nucleic acid extraction module has a movable plate component, the movable plate component by upper moving plate with And the lower moving plate being equipped with the upper moving plate is constituted;It is provided with reaction platform and dustbin below the movable plate component, institute State the front end that reaction platform is located at the movable plate component;Driving lever component is provided with below the reaction platform, in driving lever component With the driving lever pushed reaction cup waste in the dustbin;The driving lever component also has driving lever sliding rail, the driving lever Driving lever sliding block is installed, the driving lever is arranged on driving lever sliding block on sliding rail.
After reaction, reaction cup waste is pushed in the dustbin, then Biohazard Waste is gone to by dustbin week Containing box, convenient and efficient, process is pollution-free;Driving lever sliding block allows driving lever mobile in X axis, promotes each reaction cup, After reaction, reaction cup waste is pushed in the dustbin.
Further improve is that the movable plate component further includes having upper moving plate lead screw motor and lower moving plate lead screw motor, The bar magnet installed on the upper moving plate drives magnetosheath thereon to move up and down under the driving of the upper moving plate lead screw motor, institute It states the decylization installed on lower moving plate and sloughs magnetosheath on the bar magnet under the driving of the lower moving plate lead screw motor.
Further improve is that the reaction platform includes platform framework, and the platform framework has several reactions Framework has reaction compartment between two neighboring reaction framework, and the rear and front end of the platform framework is provided with cover board.
Reaction compartment makes have certain distance positioned at the intracorporal reaction cup of reaction frame, avoids and has prevented due to nucleic acid extraction Caused by pollution problem;The rear and front end of platform framework is provided with cover board and plays work that is anti-pollution and reinforcing reaction platform With.
Further improve is that the sample access mechanism is by being located at the sample pane of top half and being located at lower half portion Sample radiator constitute;It is provided with sample cover board in the sample pane, is surrounded by by the sample pane and the sample cover board Several mutually independent sample rack accommodating cavities;The sample rack is placed in the sample rack accommodating cavity, in the sample rack The bottom of accommodating cavity is provided with sliding rail;The back side of the sample pane is provided with the sample area control circuit board with detector;It is described The cooling piece that if there is sample radiator dry plate to be spaced apart from each other.
Sample access mechanism is divide into upper part and lower part, compact-sized, lower half portion is arranged to heat spreader structures, both sufficiently Its function is played, and does not influence the work of other component such as mechanical arm mechanism;Sample rack is promoted to hold sample rack by sliding rail Chamber is set, it is convenient and efficient.
Further improve is have several test tube suit holes on the sample rack, be arranged on the sample cover board There is access port identical with test tube suit hole number on the sample rack;The sample rack bottom has to be matched with the sliding rail Sliding-rail groove;Mechanical arm mechanism grabs the sample on sample rack by access port.
Further improve is that the reagent storing mechanism and the structure of the sample access mechanism are identical.
Further improve is that the external side of Z axis vertical box of the mechanical arm mechanism is provided with sampling lead screw motor, with Setting is connected in the intracorporal sampling screw rod linkage of the Z axis vertical box, is provided with sampling head, the sampling on the sampling screw rod Head vertical cabinet of Z axis described in the driving lower edge of the sampling lead screw motor moves up and down;The outside of the Y-axis horizontal box It is provided with mobile lead screw motor, is connected with setting in the intracorporal mobile screw rod linkage of the Y-axis filter box, the Z axis vertical box Slide block set on body is on the mobile screw rod, sliding block Y-axis filter box described in the driving lower edge of mobile lead screw motor Body does Y-axis horizontal movement.
It further improves and is, the three face hollow out of Y-axis horizontal box;And the sampling head is arranged by clamping element On the sampling screw rod, the clamping element is sleeved on the sampling screw rod;By using clamping element, sampling head can be carried out Replacement adjustment guarantees that sampling is accurate.
Further improve is that the hardware installation module is set with by electro-magnetic shielding cover and heat sink, and described If being provided with dry plate hardware installation plate on heat sink, there is nylon column on the hardware installation plate;There is heat dissipation on the heat sink Hole.
Electro-magnetic shielding cover can fall most electromagnetic shielding, and all circuit boards are integrated within hardware module, are shut out External electromagnetic interference problem absolutely, thus prevented because electromagnetic interference and caused by data fluctuations.
Further improve is that the PCR module has cover board, is provided with several reagent wells on the cover board;Institute It states and is provided with hot seat corresponding with the reagent wells below cover board, heating sheet and expansion are installed in the bottom of the hot seat Increase radiator;The heating sheet is between the hot seat and the amplification radiator, between amplification radiator and the cover board It is connected with nylon cylinder;The hot seated connection enters to have optical fiber.
The PCR module of above structure, can accomplish can sample i.e. checking functions, hot seated connection enters to have optical fiber, glimmering using four colors Light technology can detect four kinds of indexs of sample simultaneously;Using fiber optic conduction technology, original very large PCR equipment is contracted to Among slight PCR module, while also accomplishing that each sample is individually examined, does not interfere with each other.
Further improve is that the Biohazard Waste containing box further includes having reaction cup waste conveyer and storage There is storage mouth in the end lower section of chamber lid, the reaction cup waste conveyer, and the storage mouth is arranged in the Drawer-and-shell type box It covers;The reaction cup waste conveyer side and be located at the Drawer-and-shell type box and cover that be provided with substitute head waste de- Handler;The Biohazard Waste containing box further includes having containing box guide rail, is arranged on the base, the containing box box cover It is equipped by containing box guide-track groove arranged at the bottom and the containing box guide rail;It is additionally provided on the outside of the containing box box cover Handle.
Detailed description of the invention
It is further described with reference to the accompanying drawing with the embodiments of the present invention:
Fig. 1 is that the utility model automatically extracts amplifier molecule diagnostic device structural schematic diagram;
Fig. 2 is the nucleic acid extraction modular structure schematic diagram in Fig. 1;
Fig. 3 is the sample access mechanism structural schematic diagram in Fig. 1;
Fig. 4 is the mechanical arm mechanism structural schematic diagram in Fig. 1;
Fig. 5 is the hardware installation modular structure schematic diagram in Fig. 1;
Fig. 6 is the PCR modular structure schematic diagram in Fig. 1;
Fig. 7 is the Biohazard Waste housing box structure schematic diagram in Fig. 1;
Fig. 8 is the reagent storing mechanism structural schematic diagram in Fig. 1;
Fig. 9 is the reaction cup sample introduction mechanism structural schematic diagram in Fig. 1;
Figure 10 is the reaction cup sample introduction mechanism decomposition texture schematic diagram in Fig. 9;
Wherein: 1- nucleic acid extraction module;101- upper moving plate;102- lower moving plate;103- upper moving plate lead screw motor;104- rubbish Case;105- bar magnet;106- decylization;107- driving lever;108- reaction platform;109- movable plate component;110- driving lever component;111- driving lever Sliding rail;112- driving lever sliding block;113- lower moving plate lead screw motor;114- magnetosheath;115- platform framework;116- reacts framework;117- Reaction compartment;118- cover board;2- sample access mechanism;The sample area 201- control circuit board;202- sample cover board;203- sample Frame;204- sample pane;205- sample radiator;206- sliding rail;207- sample rack accommodating cavity;208- cooling piece;209- test tube sleeve Fill hole;210- access port;211- sliding-rail groove;3- mechanical arm mechanism;301-Y axis horizontal box;302- sliding block;303- samples screw rod Motor;304- moves screw rod;305- moves lead screw motor;The vertical cabinet of 306-Z axis;307- sampling head;308- samples screw rod 309- clamping element;4- hardware installation module;401- electro-magnetic shielding cover;402- hardware installation plate;403- nylon column;404- heat dissipation Plate;405- heat release hole;5-PCR module;501- cover board;502- heat seat;503- heating sheet;504 optical fiber;505- expands radiator; 506- reagent wells;507- nylon cylinder;6- Biohazard Waste containing box;601- reaction cup waste conveyer;602- substitute head Waste disconnecting means;603- containing box box cover;604- handle;605- containing box guide rail;606- stores mouth;607- containing box is led Track slot;7- reagent storing mechanism;8- reaction cup sample introduction mechanism;801- reaction cup;802- reaction cup box;803- reaction cup packaging consumption Material;804- idle pulley;805- reaction cup push plate;806- synchronous belt;807- synchronous pulley;808- sample introduction motor;809- sample introduction bracket; 810- cylinder;811- reaction cup packs consumption material box;812- notch;813- handle;9- pedestal;10- bracket.
Specific embodiment
As shown in Figure 1, be the full-automatic extraction amplifier molecule diagnostic device of the utility model, include pedestal 9 and set The bracket 10 on the pedestal 9 is set, further includes having:
Nucleic acid extraction module 1 is used for purifying nucleic acid, and the nucleic acid extraction module 1 is provided with reaction platform 108, reaction Cup 801 is placed in the reaction platform 108;
Sample access mechanism 2, for saving sample, the sample access mechanism 2 is located at the side of the nucleic acid extraction module 1 It face and is placed on the pedestal 9, the sample access mechanism 2 is provided with sample rack 203;
Mechanical arm mechanism 3, has Y-axis horizontal box 301, and the vertical cabinet 306 of Z axis is Y along the Y-axis horizontal box 301 Axis horizontal movement;Sampling head moves up and down on the vertical cabinet 306 of the Z axis;The Y-axis horizontal box 301 and the branch Frame 10 is connected;
Hardware installation module 4, for installing hardware device and/or other affiliated facilities, the hardware installation module 4 is set Set in the Y-axis horizontal box 301 lower section at the position that is connected with the bracket 10;
PCR module 5, for detecting sample, the setting of PCR module 5 is in 4 side of hardware installation module and is located at institute State 10 lower section of bracket;
Biohazard Waste containing box 6 includes to be arranged in 2 He of sample access mechanism for storing Biohazard Waste Containing box box cover 603 between the PCR module 5, and be installed on the pedestal 9;
The top of the Biohazard Waste containing box 6 is arranged in for storing reagent in reagent storing mechanism 7;
Reaction cup sample introduction mechanism 8 is arranged in the front end of the nucleic acid extraction module 1, and is located on the pedestal 9.
As shown in Fig. 2, nucleic acid extraction module 1 has a movable plate component 109, the movable plate component 109 by upper moving plate 101 and It is constituted with the lower moving plate 102 that the upper moving plate 101 is equipped with;The lower section of the movable plate component 109 is provided with 108 He of reaction platform Dustbin 104, the reaction platform 108 are located at the front end of the movable plate component 109;The lower section of the reaction platform 108 is arranged There is driving lever component 110, there is the driving lever 107 pushed reaction cup waste in the dustbin 104 in driving lever component 110;Institute Stating driving lever component 110 also has driving lever sliding rail 111, is equipped with driving lever sliding block 112, the driving lever 107 on the driving lever sliding rail 111 It is arranged on driving lever sliding block 112.
Movable plate component 109 further includes having upper moving plate lead screw motor 103 and lower moving plate lead screw motor 113, the upper moving plate 101 The bar magnet 105 of upper installation drives magnetosheath 114 thereon to move up and down under the driving of the upper moving plate lead screw motor 103, institute It states the decylization 106 installed on lower moving plate 102 and sloughs magnetic on the bar magnet 105 under the driving of the movable plate lead screw motor 113 Set 114;Can be with such, movable plate component is by several mutually independent upper moving plates and several mutually independent lower moving plates Constitute, a upper moving plate corresponds to each other with a lower moving plate, compounding practice, ensure that the independence of nucleic acid extraction operation with it is efficient Property;Reaction platform 108 includes platform framework 115, and the platform framework 115 has several to react framework 116, two neighboring anti- Answering has reaction compartment 117 between framework 116, the rear and front end of the platform framework 115 is provided with cover board 118.
As shown in figure 3, sample access mechanism 2 is by being located at the sample pane 204 of top half and positioned at the sample of lower half portion Radiator 205 is constituted;It is provided with sample cover board 202 in the sample pane 204, by the sample pane 204 and the sample cover board 202 are surrounded by several mutually independent sample rack accommodating cavities 207;The sample rack 203 is placed on the sample rack accommodating cavity In 207, the bottom of the sample rack accommodating cavity 207 is provided with sliding rail 206;The back side of the sample pane 204 is provided with band inspection Survey the sample area control circuit board 201 of device;The cooling piece 208 that if there is the sample radiator 205 dry plate to be spaced apart from each other;Sample There are several test tube suit holes 209 on frame 203, be provided with and test tube sleeve on the sample rack 203 on the sample cover board 202 Fill the identical access port 210 of 209 quantity of hole;203 bottom of sample rack has the sliding-rail groove matched with the sliding rail 206 211。
In the utility model embodiment, the structure of reagent storing mechanism 7 and the sample access mechanism 2 be it is identical, As shown in Figure 8;The mechanism has reagent rack to be put into EP pipe along sliding rail propulsion reagent frame, and reagent area control circuit board is with detection Whether device, can incude has reagent entrance, and bottom is by there is cooling piece reagent can be made to be in frozen state always.
As shown in figure 4, sampling lead screw motor 303 is provided on the outside of the vertical cabinet 306 of the Z axis of the mechanical arm mechanism 3, with The linkage of sampling screw rod 308 being arranged in the vertical cabinet 306 of the Z axis is connected, and is provided with sampling head on the sampling screw rod 308 307, the sampling head 307 vertical cabinet 306 of Z axis described in the driving lower edge of the sampling lead screw motor 303 moves up and down; The outside of the Y-axis horizontal box 301 is provided with mobile lead screw motor 305, and is arranged in the Y-axis horizontal box 301 The mobile linkage of screw rod 304 is connected, and the sliding block 302 on the vertical cabinet 306 of the Z axis is sleeved on the mobile screw rod 304, described The Y-axis horizontal box 301 described in the driving lower edge of mobile lead screw motor 305 of sliding block 302 does Y-axis horizontal movement.
In the present embodiment, 301 3 face hollow out of Y-axis horizontal box;And the sampling head 307 is arranged by clamping element 309 On the sampling screw rod 308, the clamping element 309 is sleeved on the sampling screw rod 308.
As shown in figure 5, hardware installation module 4 is set with by electro-magnetic shielding cover 401 and heat sink 404, and the heat dissipation If being provided with dry plate hardware installation plate 402 on plate 404, there is nylon column 403 on the hardware installation plate 402;The heat sink There is heat release hole 405 on 404.
As shown in fig. 6, PCR module 5 has cover board 501, several reagent wells 506 are provided on the cover board 501;Described The lower section of cover board 501 is provided with hot seat 502 corresponding with the reagent wells 506, is equipped with and adds in the bottom of the hot seat 502 Backing 503 and amplification radiator 505;The heating sheet 503 between the hot seat 502 and the amplification radiator 505, It is connected between the amplification radiator 505 and cover board 501 with nylon cylinder 507;The access of hot seat 502 has optical fiber 504.
As shown in Figure 7, the Biohazard Waste containing box 6 further includes having reaction cup waste conveyer 601 and storage There are storage mouth 606 in chamber lid 603, the end lower section of the reaction cup waste conveyer 601, and the setting of storage mouth 606 exists On the containing box box cover 603;The reaction cup waste conveyer 601 side and be located at the containing box box cover 603 On be provided with substitute head waste disconnecting means 602;The Biohazard Waste containing box 6 further include have containing box guide rail 605, if It sets on the pedestal 9, the containing box box cover 603 passes through containing box guide-track groove 607 arranged at the bottom and the containing box Guide rail 605 is equipped;The outside of the containing box box cover 603 is additionally provided with handle 604.
As shown in figure 9, reaction cup sample introduction mechanism 8 has reaction cup box 802, the reaction cup box 802 passes through sample introduction bracket 809 are mounted on the pedestal 9;Reaction cup 801 is assemblied in reaction cup packaging consumptive material 803, is pushed into the reaction cup box 802 It is interior;One end of the reaction cup sample introduction mechanism 8 is additionally provided with sample introduction motor 808, and the sample introduction motor 808 has synchronous pulley 807, in the other end of the reaction cup sample introduction mechanism 8, it is additionally provided with the idle pulley 804 matched with the synchronous pulley 807;It twines The synchronous belt 806 being wound on the synchronous pulley 808 and the idle pulley 804, that section being located above are placed in the reaction cup In box 802, that underlying section is placed in the outside of the reaction cup box 802;It is additionally provided on the synchronous belt 806 anti- Glass push plate 805 is answered, it is passable as variation, it is provided with reaction cup push plate in the two sides up and down of synchronous belt, in such manner, it is possible to Save the propulsion time of reaction cup packaging consumptive material;As shown in Figure 10, the sample introduction bracket 809 is made of four cylinders 810, described Four cylinders 810 are mounted on the bottom of reaction cup box 802;Reaction cup packaging consumptive material is additionally provided in the reaction cup box 802 Box 811, the reaction cup packaging consumptive material 803 is placed in the reaction cup packaging consumption material box 811, in the reaction cup box 802 One end, and be located at the sample introduction motor 808 above be provided with a notch 812;Reaction cup packs consumptive material 803 from diagram right side (803 sides in Fig. 9) are manually pushed back into, and (801 sides in Fig. 9) reaction cup 801 enters nucleic acid extraction module on the left of diagram 1;The end of the reaction cup packaging consumption material box 811 is provided with leader 813, and the cross section of the reaction cup box 802 is rectangular Shape;The top of the reaction cup packaging consumption material box 811 is opening, and the sample introduction motor 808 is stepper motor.
When specifically used, reaction cup 801 is assemblied in reaction cup packaging consumptive material 803, as shown in figure 9, sample introduction motor 808 is dynamic Make, drive synchronous pulley 807, synchronous belt 806 rotates, and the reaction cup push plate 805 on synchronous belt 806 is mobile, reaction cup packaging consumption Material 803 is manually pushed back into reaction cup box 802 in reaction cup packaging consumption material box 811;Reaction cup 801 is by reaction cup push plate 805 It is pushed into nucleic acid extraction module 1, as shown in Fig. 2, reaction cup 801 is allocated in reaction framework 116 by driving lever 107;Utilize machinery Arm mechanism 3 is originally added in reaction cup 801 from sampling in sample access mechanism 2, and mechanical arm mechanism 3 is moved along X-axis over the mount 10 It is dynamic, it can adjust X axis position;After reaction, nucleic acid extracts the driving lever 107 into reagent storing mechanism 7 by mechanical arm mechanism 3 Reaction cup waste is pushed in dustbin 104, the reaction cup waste in dustbin 104 passes through reaction cup shown in fig. 7 Waste conveyer 601 is sent in the containing box box cover in Biohazard Waste containing box 6, and there are also substitute head waste is de- on side Handler 602 drops to substitute head in containing box box cover;Mechanical arm mechanism 3 will be equipped with reagent from reagent storing mechanism 7 again EP pipe extract to PCR module 5 and carry out augmentation detection, detection system uses fiber optic conduction technology, by original very large PCR equipment It is contracted among slight PCR module, while also accomplishing that each sample is individually examined, do not interfere with each other.
The basic principles and main features and advantage of the utility model have been shown and described above.The technical staff of the industry It should be appreciated that the present utility model is not limited to the above embodiments, the above embodiments and description only describe this The principle of utility model, on the premise of not departing from the spirit and scope of the utility model, the utility model also has various change And improvement, such as some adjustment are done for the position for being mounted on the base all parts, these changes and improvements both fall within requirement In the scope of the utility model of protection.The utility model requires protection scope is by appended claims and its equivalent circle It is fixed.

Claims (6)

1. a kind of reaction cup sample introduction mechanism, which is characterized in that the reaction cup sample introduction mechanism distributes reaction cup box along the longitudinal, described Reaction cup box is mounted on the base by sample introduction bracket;Reaction cup is assemblied in reaction cup packaging consumptive material, is pushed into the reaction cup In box;One end of the reaction cup sample introduction mechanism is additionally provided with sample introduction motor, and the sample introduction motor has synchronous pulley, described anti- The other end for answering glass sample introduction mechanism is additionally provided with the idle pulley matched with the synchronous pulley;Be wrapped in the synchronous pulley and Synchronous belt on the idle pulley, that section being located above are placed in the reaction cup box, that underlying section is placed in institute State the outside of reaction cup box;Reaction cup push plate is additionally provided on the synchronous belt.
2. reaction cup sample introduction mechanism according to claim 1, which is characterized in that the sample introduction bracket is by four cylinder structures At four cylinders are mounted on the bottom of reaction cup box;Reaction cup packaging consumption material box is additionally provided in the reaction cup box, The reaction cup packaging consumptive material is placed in the reaction cup packaging consumption material box.
3. reaction cup sample introduction mechanism according to claim 1, which is characterized in that in one end of the reaction cup box, and position A notch is provided with above the sample introduction motor;One end of reaction cup box of the notch is provided with as input end.
4. reaction cup sample introduction mechanism according to claim 2 or 3, which is characterized in that the reaction cup packaging consumption material box End is provided with leader.
5. reaction cup sample introduction mechanism according to claim 4, which is characterized in that the cross section of the reaction cup box is rectangular Shape;It is opening above the reaction cup packaging consumption material box.
6. reaction cup sample introduction mechanism according to claim 5, which is characterized in that the sample introduction motor is stepper motor.
CN201820784913.0U 2018-05-24 2018-05-24 Reaction cup sample introduction mechanism Active CN208206990U (en)

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Application Number Priority Date Filing Date Title
CN201820784913.0U CN208206990U (en) 2018-05-24 2018-05-24 Reaction cup sample introduction mechanism

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Application Number Priority Date Filing Date Title
CN201820784913.0U CN208206990U (en) 2018-05-24 2018-05-24 Reaction cup sample introduction mechanism

Publications (1)

Publication Number Publication Date
CN208206990U true CN208206990U (en) 2018-12-07

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Application Number Title Priority Date Filing Date
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Country Link
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