CN208206634U - Storage device of the band from mixing reagent - Google Patents
Storage device of the band from mixing reagent Download PDFInfo
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- CN208206634U CN208206634U CN201820859075.9U CN201820859075U CN208206634U CN 208206634 U CN208206634 U CN 208206634U CN 201820859075 U CN201820859075 U CN 201820859075U CN 208206634 U CN208206634 U CN 208206634U
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- reagent
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Abstract
A kind of band mixes the storage device of reagent certainly, it is characterized by: the device includes driving mechanism, the driving mechanism includes driving portion and transmission belt, the transmission belt is connect with rotating shaft transmission, the shaft is connect with reagent disc, the multiple kits placement position for accommodating kit is provided on the reagent disc, the driving portion driving transmission belt drives shaft rotation;It is additionally provided with bearing in the shaft, fixed gear, the fixation gear and shaft relative rotation are fixed on the bearing, is provided with the full circle gear teeth on the fixation gear;The kit has been arranged radially multiple reagent bottles and has placed position, close to the reagent bottle of fixed gear places the reagent bottle for being provided with the gear teeth on position, the gear teeth completely enclose the gear teeth with fixed gear and are meshed.With rotation magnetic bead solution is uniformly mixed with that can realize that reagent bottle revolves simultaneously, and reagent bottle is put into convenience, rotates the advantages of blending process is less prone to tooth butt phenomenon.
Description
Technical field
Originally practical to belong to in-vitro diagnosis equipment technical field, and in particular to a kind of band mixes the storage device of reagent certainly.
Background technique
In vitro in diagnostic analysis instrument, it will appear sedimentation phenomenon since bead density is greater than water density, so drawing
Before magnetic bead, mixing processing is carried out to magnetic bead solution.Currently on the market in immunity analysis instrument, magnetic bead automatic mixing device is main
Reagent bottle rotation is driven by motor, then passes through the mixing method of tooth engagement rotation in tooth on magnetic bead bottle and reagent cabin;It is this
Single rotation blending manner is easy to cause and mixes uneven, unstable phenomenon appearance;Reach better mixing if necessary
Effect, it is desirable to provide independent power device, not only increase equipment is integrally born a heavy burden and cost, while this mode is mixed in dish type
It is also not easily accomplished in the structure of device;Further, since needing many reagent bottles of circumferential facility, part factory on this evenly mixing device
Family for convenient for being put into of reagent bottle, prevent reagent bottle from blocking, be provided with notch at big dish type internal-gear, though this comes
Right reagent bottle is put into conveniently but drives tooth rotary course on magnetic bead bottle in internal tooth, since the presence of notch leads to two side's gears
Engagement is inaccurate and tooth butt phenomenon occurs, and leading to gear wear, entire rotation is affected simultaneously.
Utility model content
The utility model be directed to the prior art above-mentioned deficiency, provide it is a kind of can realize simultaneously reagent bottle revolution and rotation make
Magnetic bead solution be uniformly mixed, and reagent bottle be put into conveniently, rotation blending process be less prone to tooth butt phenomenon band from mix examination
The storage device of agent.
In order to solve the above-mentioned technical problem, the technical solution of this practical use are as follows: a kind of band mixes the storage dress of reagent certainly
It sets, which includes driving mechanism, and the driving mechanism includes driving portion and transmission belt, the transmission belt and rotating shaft transmission
Connection, the shaft are connect with reagent disc, and the multiple kits placement position for accommodating kit is provided on the reagent disc,
The driving portion driving transmission belt drives shaft rotation;It is additionally provided with bearing in the shaft, is fixed on the bearing
There are fixed gear, the fixation gear and shaft relative rotation, is provided with the full circle gear teeth on the fixation gear;Described
Kit has been arranged radially multiple reagent bottles and has placed position, and the examination that the gear teeth are provided on position is placed close to the reagent bottle of fixed gear
Agent bottle, the gear teeth completely enclose the gear teeth with fixed gear and are meshed.
Using the above structure, the utility model drives transmission belt to drive shaft rotation by driving portion, and shaft drives it again
On reagent disc spins reagent disc rotating power source drive kit to circumferentially rotate, and kit is close to the reagent of fixed gear
Bottle is placed and is provided with the reagent bottles of the gear teeth on position, and the gear teeth of the reagent bottle with the gear teeth are meshed with fixed gear, shaft and
Reagent disc connection, realizes the rotation of reagent bottle while reagent disc rotating power source drives kit to circumferentially rotate;To mention
The uniformity that height mixes;More it is outstanding be this practical use fixation gear on be provided with the full circle gear teeth, the gear teeth of reagent bottle
It is in meshing state always with fixed gear, avoids the generation of tooth butt phenomenon.
Preferably, the lower end surface of the gear teeth of the reagent bottle with the gear teeth is provided with wedge groove, the structure is convenient
The insertion of reagent bottle a, and at the same time guiding role, the convenient full circle gear teeth with fixed gear are played in the setting of wedge groove
Accurate engagement.
Preferably, the band, from the storage device for mixing reagent, which further includes sample transfer driving section, described
Sample transfer transmission portion in the outer ring of reagent disc and can and reagent disc between generate relative rotation;The sample, which shifts, to be passed
Dynamic portion includes the sample splint for placing the specimen holder of sample cell and fixed specimen holder, and the sample splint passes through transmission belt
It is sequentially connected with sample driving device;Using the structure, may be implemented for reagent disc and sample transfer driving section to be blended in a set of
In device, space is saved, integrated module degree height also can increase the efficiency for being loaded reagent adding;It is driven simultaneously by sample
Device drives sample transfer driving section rotation, enables sample smoothly up to load position.
Preferably, being provided with sample cell accommodating hole on the specimen holder, it is provided on the inner wall of the accommodating hole
Elastic deformation structure, the elastic deformation structure is for compressing sample cell;Sample cell can be made using the structure
It can be firmly fixed after being installed to accommodating hole, will not shake in sample splint rotary course;Further, it is also possible to guarantee to hold
The aperture for setting hole has certain deformation space, meets the placement of the sample cell of different diameter values, improves adaptability.
It include the metal clips being connect with accommodating hole inner sidewall, institute as further preferred, described elastic deformation structure
The outside and sample cell contact site for the metal clips stated are provided with plastic shrapnel;Pass through the setting of the above-mentioned double-deck elastic slice, internal layer
Metal clips anti-fatigue ability it is strong, can remain the pretightning force to sample cell, and the plastic shrapnel of outer layer is realized and sample
The soft contact of quality control takes process in sample cell, will not cause to damage to tube body, reduces frictional force.
Preferably, being provided with the second code-disc on the lower end surface of the sample splint, second code-disc is circumferentially set
Multiple yards of teeth are equipped with, the code tooth and sample accommodating hole correspond, and second code-disc is used cooperatively with the second optocoupler;
It is high that detection of loss of mains, rotational positioning precision may be implemented using the above structure, guarantee that sample cell can precisely reach sample position.
Preferably, the band, from the storage device for mixing reagent, which further includes reagent storage refrigeration mechanism, institute
The reagent storage refrigeration mechanism stated is located at the lower section of reagent disc, including refrigeration media storage chamber, refrigerates the intracavitary setting of media storage
There is cyclic water channel, the cyclic water channel in the shape of a spiral, is radially gradually reduced from outside to inside, and the cyclic water channel is provided with
Inlet and outlet, the water inlet are located at the outermost of cyclic water channel radial direction, and the water outlet is located at cyclic water channel
Radial most inner side;And the upper surface of water outlet is slightly above the cavity upper surface for refrigerating media storage chamber;Using the above structure, from
Water inlet is passed through cold water, and cold water is flowed along the flow of media channel that cyclic water channel is constituted, and is gradually filled with entire refrigeration from outside
Then media storage chamber is flowed out by water outlet, continuous to recycle, and guarantee refrigerates the reagent on top;Cyclic water channel is in
Helical form improves the contact area in water route Yu reagent disc lower part, improves cold storage effect;It omits the upper surface that water outlet is set simultaneously
Higher than the cavity upper surface of refrigeration media storage chamber, it is ensured that circulating water cavity upper and lower end face is hot with Cold Water Exposure, enhancing always
Exchange rate.
It is flushed as the upper surface of further preferred, described water inlet with the lower end surface of cyclic water channel, using the structure,
Water inlet, in top surface, improves the flowing of water body in bottom surface, water outlet, prevents water-setting poly-, improves refrigeration effect.
Preferably, being provided with the first code-disc on the lower end surface of the shaft, the code-disc is circumferentially provided with multiple
Code tooth, the code tooth and kit are placed position and are corresponded, and first code-disc is used cooperatively with the first optocoupler;Using upper
Stating structure may be implemented detection of loss of mains, rotational positioning precision height, guarantee that kit can precisely reach sample position.
Preferably, being provided with vertical card slot on the side wall of the kit, kit is placed the corresponding position in position and is set
It is equipped with the card muscle with card slot cooperation clamping;Using the structure, can guarantee not jump steadily when agent transfer and magnetic bead bottle mix
Dynamic shake.
Detailed description of the invention
Fig. 1 is memory device structure schematic diagram of this practical band from mixing reagent.
Fig. 2 is storage device section view figure structure schematic representation of this practical band from mixing reagent.
Fig. 3 is the structural schematic diagram of this practical reagent disc and driving mechanism cooperation.
Fig. 4 is the section view figure structure schematic representation of Fig. 3.
Fig. 5 is the vertical view figure structure schematic representation of this practical reagent disc.
Fig. 6 is this practical reagent bottle structural schematic diagram with the gear teeth.
Fig. 7 is the three-dimensional figure structure schematic representation of this practical reagent disc.
Fig. 8 is this practical reagent cartridge configuration schematic diagram.
Fig. 9 is that this practical sample shifts driving section structural schematic diagram.
Figure 10 is this practical specimen holder structural schematic diagram.
Figure 11 is the amplification figure structure schematic representation in this portion practical specimen holder A.
Figure 12 is that this practical reagent stores refrigeration mechanism vertical view figure structure schematic representation.
Figure 13 is that this practical reagent stores refrigeration mechanism structure vertical cross-sectional schematic diagram.
Figure 14 is that this practical reagent stores refrigeration mechanism structure laterally to cross-sectional view schematic diagram.
Specific embodiment
The utility model is described in detail with specific embodiment with reference to the accompanying drawings of the specification.
As shown in figures 1-6: for a kind of band of the utility model from the storage device for mixing reagent, which includes driving machine
Structure, the driving mechanism include driving portion 1 (such as driving motor) and transmission belt 2 such as synchronous belt, the transmission belt and shaft
(transmission shaft) 3 is sequentially connected, and the shaft is connect with reagent disc 4, is provided on the reagent disc and accommodates the more of kit 5
A kit is placed position 6 (kit of the invention places position as shown in fig. 7, being radially arranged on reagent disc), described
Driving portion drives transmission belt to drive shaft rotation;It is additionally provided with bearing in the shaft, is fixed with fixation on the bearing
Gear 7, the fixation gear and shaft relative rotation (such as shaft rotates and fixes gear and do not rotate), the fixation gear
On be provided with the full circle gear teeth (be evenly equipped with the gear teeth on the entire outer circumferential wall of gear, will not jagged equal setting);The examination
Agent box has been arranged radially multiple reagent bottles and has placed position, and the reagent that the gear teeth are provided on position is placed close to the reagent bottle of fixed gear
8 (this reagent bottle of the present embodiment can use magnetic bead bottle) of bottle, the gear teeth (gear teeth on magnetic bead bottle) and the full circle for fixing gear
The gear teeth are meshed.
Using the above structure, the utility model drives transmission belt to drive shaft rotation by driving portion, and shaft drives it again
On reagent disc spins reagent disc rotating power source drive kit to circumferentially rotate, and kit is close to the reagent of fixed gear
Bottle is placed and is provided with the reagent bottles of the gear teeth on position, and the gear teeth of the reagent bottle with the gear teeth are meshed with fixed gear, shaft and
Reagent disc connection, realizes the rotation of reagent bottle while reagent disc rotating power source drives kit to circumferentially rotate;To mention
The uniformity that height mixes;More it is outstanding be this practical use fixation gear on be provided with the full circle gear teeth, the gear teeth of reagent bottle
It is in meshing state always with fixed gear, avoids the generation of tooth butt phenomenon.This practical above-mentioned reagent disc is contained in reagent
In bucket, the top of staving is covered by the big lid 10 in reagent cabin, is only covered setting sampling hole greatly in reagent cabin, is prevented from trying
Agent is contaminated.
This practical above-mentioned driving motor and synchronous belt are set between the output shaft and shaft of driving motor as shown in Fig. 1
Synchronous belt is set, shaft is equipped with synchronous pulley, drives shaft rotation by synchronous belt.
As shown in attached drawing 1-2 and 9, which further includes sample transfer driving section 13, and the sample shifts transmission portion
In the outer ring of reagent disc and relative rotation can be generated between reagent disc;The sample transfer driving section includes for placing sample
The sample splint 13.2 of the specimen holder 13.1 of quality control and fixed specimen holder, the sample splint are driven by transmission belt 2 and sample
Dynamic device 13.3 is sequentially connected;Using the structure, may be implemented reagent disc and sample transfer driving section being blended in set of device
In, save space, integrated module degree height also can increase the efficiency for being loaded reagent adding;Pass through sample driving device simultaneously
Sample transfer driving section rotation is driven, enables sample smoothly up to load position.Specifically from the finding of attached drawing 1 and 9, pass through one
For a driving motor as power source, the lower position of sample splint is synchronous belt wheel structure, and the output shaft of driving motor passes through same
Step band connect with synchronous belt pulley transmission, realizes that shifting driving section to entire sample rotates in a circumferential direction driving.
As shown in attached drawing 9 and 11, be provided with sample cell accommodating hole 13.4 on the specimen holder, the accommodating hole it is interior
Elastic deformation structure 13.5 is provided on wall, the elastic deformation structure is for compressing sample cell;Using the structure
It can be firmly fixed after sample cell being made to be installed to accommodating hole, will not shake in sample splint rotary course;This
Outside, it can also be ensured that the aperture of accommodating hole has certain deformation space, meets the placement of the sample cell of different diameter values, improves suitable
Ying Xing;The specific elastic deformation structure includes the metal clips 13.6 connecting with accommodating hole inner sidewall, the metal
The outside and sample cell contact site of elastic slice are provided with plastic shrapnel 13.7;Pass through the setting of the above-mentioned double-deck elastic slice, the gold of internal layer
It is strong to belong to elastic slice anti-fatigue ability, can remain the pretightning force to sample cell, and the plastic shrapnel of outer layer is realized and sample cell
Soft contact, take process in sample cell, tube body will not be caused to damage, reduce frictional force.As shown in attached drawing 9-11, this is practical
Sample cell accommodating hole be semi-open type, which mainly considers that sample cell is conveniently taken, in addition, each accommodating hole is corresponding
An accommodation groove is vertically corresponded in sample splint, the two combines the fixed bit for constituting sample cell up and down.
As shown in Fig. 9, the second code-disc 14, the second code-disc week are provided on the lower end surface of the sample splint
To multiple yards of teeth are provided with, the code tooth and sample accommodating hole are corresponded, and second code-disc is matched with the second optocoupler 15
It closes and uses;It is high that detection of loss of mains, rotational positioning precision may be implemented using the above structure, guarantee that sample cell can precisely reach sampling
Position.
As shown in attached drawing 1-2 and 12-14, which further includes reagent storage refrigeration mechanism 16, and the reagent storage is cold
Hiding mechanism is located at the lower section of reagent disc, including refrigeration media storage chamber 16.1, refrigerates that media storage is intracavitary to be provided with cyclic water channel
16.2, the cyclic water channel in the shape of a spiral, is radially gradually reduced from outside to inside, and the cyclic water channel is provided with water inlet
16.3 and water outlet 16.4, the water inlet be located at the outermost of cyclic water channel radial direction, the water outlet is located at recirculated water
The most inner side of road radial direction;And the upper surface of water outlet is slightly above the cavity upper surface for refrigerating media storage chamber;Using the above structure,
It is passed through cold water from water inlet, cold water is flowed along the flow of media channel that cyclic water channel is constituted, and is gradually filled with from outside entire cold
Media storage chamber is hidden, is then flowed out by water outlet, continuous to recycle, guarantee refrigerates the reagent on top;Cyclic water channel
In the shape of a spiral, the contact area in water route Yu reagent disc lower part is improved, cold storage effect is improved;The upper surface of water outlet is set simultaneously
Slightly above refrigerate media storage chamber cavity upper surface, it is ensured that circulating water cavity upper and lower end face always with Cold Water Exposure, enhancing
Rate of heat exchange.It is flushed as the upper surface of further preferred, described water inlet with the lower end surface of cyclic water channel, using the knot
Structure, water inlet, in top surface, improve the flowing of water body in bottom surface, water outlet, prevent water-setting poly-, improve refrigeration effect.
Reagent stores refrigeration mechanism leak in order to prevent, as shown in Fig. 13, stores refrigeration mechanism and reagent barrel in reagent
Bottom surface between be provided with sealing ring 16.5.
As shown in attached drawing 1-2, the first code-disc 11 is provided on the lower end surface of the shaft, the code-disc is circumferentially arranged
There are multiple yards of teeth, the code tooth and kit are placed position and corresponded, and first code-disc makes with the cooperation of the first optocoupler 12
With;It is high that detection of loss of mains, rotational positioning precision may be implemented using the above structure, guarantee that kit can precisely reach sampling position
It sets.
As shown in attached drawing 7-8, vertical card slot 5.1 is provided on the side wall of this practical kit 5, it is right that kit places position
The position answered is provided with the card muscle 6.1 with card slot cooperation clamping;Using the structure, can guarantee mixed in agent transfer and magnetic bead bottle
It does not beat steadily when even shake;In addition, it can be three that the reagent bottle of kit of the invention, which places position, wherein for placing magnetic
The reagent bottle of pearl bottle places position close to most the inside, and the placement position will guarantee that the gear teeth of magnetic bead bottle can be with the wheel of fixed gear
Tooth contact engagement, rotation.
Above-described embodiment is only the explanation to specific one or more of embodiments of the invention, not to limit of the invention
System.
Claims (10)
1. the storage device that a kind of band mixes reagent certainly, it is characterised in that: the device includes driving mechanism, the driving mechanism
Including driving portion and transmission belt, the transmission belt is connect with rotating shaft transmission, and the shaft is connect with reagent disc, the examination
The multiple kits placement position for accommodating kit is provided on agent disk, the driving portion driving transmission belt drives shaft rotation;
It is additionally provided with bearing in the shaft, fixed gear is fixed on the bearing, the fixation gear is opposite with shaft
It rotates, is provided with the full circle gear teeth on the fixation gear;The kit has been arranged radially multiple reagent bottles and has placed position, leans on
The reagent bottle of nearly fixed gear places the reagent bottle that the gear teeth are provided on position, the gear teeth completely enclose the gear teeth with fixed gear and mutually nibble
It closes.
2. the storage device that band according to claim 1 mixes reagent certainly, it is characterised in that: the examination with the gear teeth
The lower end surface of the gear teeth of agent bottle is provided with wedge groove.
3. the storage device that band according to claim 1 mixes reagent certainly, it is characterised in that: the device further includes that sample turns
Driving section is moved, the sample transfer transmission portion is in the outer ring of reagent disc and can generate relative rotation between reagent disc;Institute
The sample transfer driving section stated includes the sample splint for placing the specimen holder of sample cell and fixed specimen holder, the sample
Supporting plate is sequentially connected by transmission belt and sample driving device.
4. the storage device that band according to claim 3 mixes reagent certainly, it is characterised in that: be arranged on the specimen holder
There is sample cell accommodating hole, elastic deformation structure is provided on the inner wall of the accommodating hole, the elastic deformation structure is used for
Sample cell is compressed.
5. the storage device that band according to claim 4 mixes reagent certainly, it is characterised in that: the elastic deformation structure
Including the metal clips connecting with accommodating hole inner sidewall, the outside and sample cell contact site of the metal clips are provided with modeling
Expect elastic slice.
6. the storage device that band according to claim 3 mixes reagent certainly, it is characterised in that: under the sample splint
The second code-disc is provided on end face, second code-disc is circumferentially provided with multiple yards of teeth, the code tooth and sample accommodating hole
It corresponds, second code-disc is used cooperatively with the second optocoupler.
7. the storage device that band according to claim 1 mixes reagent certainly, it is characterised in that: the device further includes that reagent is deposited
Refrigeration mechanism is stored up, the reagent storage refrigeration mechanism is located at the lower section of reagent disc, including refrigeration media storage chamber, refrigerates medium
Cyclic water channel is provided in storage chamber, the cyclic water channel in the shape of a spiral, is radially gradually reduced from outside to inside, and described follows
Ring water channel is provided with inlet and outlet, and the water inlet is located at the outermost of cyclic water channel radial direction, the water outlet
Positioned at the most inner side of cyclic water channel radial direction;And the upper surface of water outlet is slightly above the cavity upper surface for refrigerating media storage chamber.
8. the storage device that band according to claim 7 mixes reagent certainly, it is characterised in that: the upper end of the water inlet
Face is flushed with the lower end surface of cyclic water channel.
9. the storage device that band according to claim 1 mixes reagent certainly, it is characterised in that: the lower end surface of the shaft
On be provided with the first code-disc, the code-disc is circumferentially provided with multiple yards of teeth, and it is a pair of that the code tooth and kit place position one
It answers, first code-disc is used cooperatively with the first optocoupler.
10. the storage device that band according to claim 1 mixes reagent certainly, it is characterised in that: the side of the kit
Vertical card slot is provided on wall, kit places the corresponding position in position and is provided with the card muscle being clamped with card slot cooperation.
Applications Claiming Priority (2)
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CN2017211799892 | 2017-09-15 | ||
CN201721179989 | 2017-09-15 |
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110160854A (en) * | 2019-05-23 | 2019-08-23 | 深圳安赛诊断技术有限公司 | It is a kind of to keep the device of bead suspension uniformity, method and application thereof |
CN110456091A (en) * | 2019-10-11 | 2019-11-15 | 潍坊市康华生物技术有限公司 | A kind of reagent disc magnetic bead evenly mixing device and application method |
CN111380284A (en) * | 2020-03-23 | 2020-07-07 | 珠海丽珠试剂股份有限公司 | Reagent refrigerating plant and check out test set |
CN113398806A (en) * | 2020-03-17 | 2021-09-17 | 深圳迎凯生物科技有限公司 | Blending device |
CN113740549A (en) * | 2021-08-27 | 2021-12-03 | 中元汇吉生物技术股份有限公司 | Reagent disk structure and sample analyzer |
-
2018
- 2018-06-05 CN CN201820859075.9U patent/CN208206634U/en active Active
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110160854A (en) * | 2019-05-23 | 2019-08-23 | 深圳安赛诊断技术有限公司 | It is a kind of to keep the device of bead suspension uniformity, method and application thereof |
CN110456091A (en) * | 2019-10-11 | 2019-11-15 | 潍坊市康华生物技术有限公司 | A kind of reagent disc magnetic bead evenly mixing device and application method |
CN110456091B (en) * | 2019-10-11 | 2020-02-07 | 潍坊市康华生物技术有限公司 | Reagent disk magnetic bead mixing device and using method |
CN113398806A (en) * | 2020-03-17 | 2021-09-17 | 深圳迎凯生物科技有限公司 | Blending device |
CN111380284A (en) * | 2020-03-23 | 2020-07-07 | 珠海丽珠试剂股份有限公司 | Reagent refrigerating plant and check out test set |
CN113740549A (en) * | 2021-08-27 | 2021-12-03 | 中元汇吉生物技术股份有限公司 | Reagent disk structure and sample analyzer |
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