CN208151343U - Full automatic instrument for extracting nucleic acid - Google Patents

Full automatic instrument for extracting nucleic acid Download PDF

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Publication number
CN208151343U
CN208151343U CN201820181113.XU CN201820181113U CN208151343U CN 208151343 U CN208151343 U CN 208151343U CN 201820181113 U CN201820181113 U CN 201820181113U CN 208151343 U CN208151343 U CN 208151343U
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China
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nucleic acid
rotation axis
carrier
tip
component
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CN201820181113.XU
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Chinese (zh)
Inventor
王斌
李晨辉
张振利
邓博雅
陈杰
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Beijing Tongli Chuang Hui Instrument Co Ltd
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Beijing Tongli Chuang Hui Instrument Co Ltd
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Abstract

The utility model relates to a kind of Full automatic instrument for extracting nucleic acid, including the platform assembly, nucleic acid extraction component and automatic liquid relief component being arranged on bottom plate, platform assembly includes the reagent trough carrier being set on bottom plate, EP pipe carrier, heparin tube carrier, the first deep-well plates carrier and TIP carriers;The side of platform assembly is equipped with several second deep-well plates, and nucleic acid extraction component includes can be in the second deep-well plates upper direction and the nucleic acid extraction arm that can be gone up and down;Automatic liquid relief component includes can be in nucleic acid extraction component and platform assembly upper direction and the liquid relief arm that can be gone up and down.The utility model is mainly by liquid relief part and nucleic acid extraction part, and other mould groups are integrated, realize the full-automatic extraction process of the nucleic acid from sample to purifying, avoid interference of the manual operation to result, reduce labor intensity, reduce consumptive material waste, improves extraction accuracy, accelerate extraction rate.

Description

Full automatic instrument for extracting nucleic acid
Technical field
The utility model belongs to Medical Devices manufacturing field, and in particular to a kind of Full automatic instrument for extracting nucleic acid.
Background technique
Nucleic acid be by many nucleotide polymerizations at large biological molecule compound, be life one of most basic substance.Core Acid is widely present in all animal and plant cells, in microbial body, and the intracorporal nucleic acid of biology often forms nucleoprotein in conjunction with protein. Recently as the high speed development of molecular biology, the molecular diagnosis and detection technique based on nucleic acid are Sino-Japan in numerous areas Benefit highlights vital effect.Nucleic acid needs needed for experiment and detection carry out purification from biological sample, but want To multiple samples carry out purifying or it is extremely difficult.This process not only needs to select suitable purification technique, but also works Amount is also especially big, is difficult to meet the demand for extracting high-throughput sample purifying currently developed rapidly.
Most of instrument for extracting nucleic acid is all made of paramagnetic particle method and extracts to nucleic acid at present, the core used during the extraction process Sour extraction apparatus is the instrument that the extraction work of sample nucleic acid is automatically performed using matched magnetic bead nucleic acid extracting reagent.At present Instrument for extracting nucleic acid be divided into two classes:One kind is large-scale automatic fluid work station, obtains nucleic acid, advantage by transfer liquid It is that fully automatic operation can be achieved, the disadvantage is that being not exclusively suitable for nucleic acid extraction, and takes a long time, each nucleic acid extraction duration is greater than one Hour;Another kind of is small-sized magnetic bar type instrument for extracting nucleic acid, obtains nucleic acid by transfer magnetic bead, advantage be it is time-consuming shorter, need 30 to 50 minutes, the disadvantage is that need to be with being pre-installed or the matched reagent that dispenses by hand of scene cannot be full-automatic without liquid separation and pipetting function Handle many experiments sample.
Utility model content
To solve the above-mentioned problems, the utility model provide it is a kind of efficiently, be quickly obtained the complete of high-purity sample of nucleic acid Automatic instrument for extracting nucleic acid, concrete scheme are as follows:
A kind of Full automatic instrument for extracting nucleic acid, including the platform assembly, nucleic acid extraction component and automatic shifting being arranged on bottom plate Liquid component, for the platform assembly for placing various reagents and container, the position of the reagent and container on the bottom plate can With independent assortment, the nucleic acid extraction component is used for magnetic bead transfer type nucleic acid extraction, and the automatic liquid relief component is used for described Accurate liquid transfer between platform assembly and the nucleic acid extraction component.
The platform assembly includes the reagent trough carrier being set on the bottom plate, EP pipe carrier, heparin tube carrier, PCR Eight connect EP pipe carrier and TIP carriers, and the reagent trough carrier is equipped with reagent trough, and the EP pipe carrier is equipped with EP pipe support, The heparin tube carrier is equipped with heparin tube, and the PCR eight connects EP pipe carrier and is equipped with the company of PCR eight EP pipe, the TIP carrier It is equipped with TIP framves.
The nucleic acid extraction component includes 96 deep-well plates being set on the bottom plate, above 96 deep-well plates First X-axis movement mechanism, the first Z axis movement mechanism on the first X-axis movement mechanism and be set to first Z axis Nucleic acid extraction arm on movement mechanism;Several magnetosheath framves, the magnetosheath are equipped with by the first connecting plate on the nucleic acid extraction arm Frame is equipped with several vertical arrangements and can protrude into the magnetosheath in 96 deep-well plates;The nucleic acid extraction arm is located at the magnetosheath frame Top by the second connecting plate be equipped with several bar magnet framves, the bar magnet frame be equipped with several magnetic that can be protruded into the magnetosheath Stick.
Further, the lower section of 96 deep-well plates is equipped with several heating components, and the heating component includes heat block, institute The lower section for stating heat block is equipped with adding thermal resistance, and collet is equipped between the adding thermal resistance and the bottom plate.
Further, retaining device is additionally provided on the bottom plate, the retaining device includes being set in 96 deep-well plates The baffle of side, one end of the baffle are equipped with the first rotation axis and the second rotation axis of parallel arrangement, first rotation axis away from It is less than second rotation axis with a distance from the baffle edge at a distance from the baffle edge;First rotation axis and institute The one end for stating the second rotation axis is connected with driving mechanism for driving the baffle plate turning, and the driving mechanism can drive baffle It overturns to the surface of 96 deep-well plates.
Further, the driving mechanism includes baffle shell, and first rotation axis passes through the baffle shell and passes through First connecting rod is connected with third rotation axis, and second rotation axis passes through the baffle shell and is connected with energy by the second connecting rod Second rotation axis is enough driven to make the transmission component of circular motion;The input terminal of the transmission component is equipped with stepper motor, institute The first movement slots offered on baffle shell for first rotation axis movement are stated, the lower section of first movement slots, which is equipped with, to be supplied Second movement slots of the second rotation axis movement, the radian of second movement slots is greater than first movement slots, when described The height and second rotation axis of first rotation axis described in when second rotation axis moves to the highest point of second movement slots It is identical;The baffle circuit board connecting with the stepper motor is additionally provided in the baffle shell.
The automatic liquid relief component includes the second X-axis movement mechanism being set to above the nucleic acid extraction component and is set to The first Y-axis movement mechanism on the second X-axis movement mechanism, the liquid relief arm are set on the first Y-axis movement mechanism, institute Liquid relief arm is stated equipped with several liquid relief units, each described liquid relief unit includes being set on the second Y-axis movement mechanism 2nd Z shaft movement mechanism and the probe tube being set on the second Z axis movement mechanism.
Further, waste gathering device is additionally provided on the bottom plate, the waste gathering device includes that auxiliary is moved Liquid arm unloads TIP devices for what discarded TIP head was removed from the probe tube;It is described to unload being arranged right below for TIP devices Waste slideway, the bottom of the waste slideway are equipped with discarded TIP storage devices.
Further, the EP pipe carrier is equipped with the guided way of several parallel arrangements, and the bottom of the EP pipe support is equipped with With the card slot of guided way cooperation, the EP pipe carrier is made of polyformaldehyde material.
Further, the surrounding of the TIP carrier is coated with side plate, if the carrier top surface TIP is equipped with capable person institute State the elastic slice that TIP framves are connected on the TIP carrier.
The beneficial effects of the utility model are:The utility model provides a kind of full-automatic nucleic acid-extracting apparatus, mainly Integrated by liquid relief part and nucleic acid extraction part and other mould groups, realize the nucleic acid from sample to purifying it is complete from Dynamic extraction process, avoids interference of the manual operation to result, reduces labor intensity, reduces consumptive material waste, improves Precision is taken, extraction rate is accelerated.
Detailed description of the invention
The overall structure diagram of Fig. 1 the utility model embodiment 1,
The structural schematic diagram of 1 platform assembly of Fig. 2 the utility model embodiment,
The structural schematic diagram of 1 nucleic acid extraction component of Fig. 3 the utility model embodiment,
The structural schematic diagram of 1 liquid-transfering device of Fig. 4 the utility model embodiment,
The structure top view of 1 retaining device of Fig. 5 the utility model embodiment,
The structural side view of 1 retaining device of Fig. 6 the utility model embodiment,
The schematic diagram of internal structure of 1 retaining device of Fig. 7 the utility model embodiment,
The structural schematic diagram of 1 heating component of Fig. 8 the utility model embodiment,
The structural schematic diagram of Fig. 9 the utility model embodiment 1EP pipe carrier,
The structural schematic diagram of Figure 10 1TIP carriers of the utility model embodiment,
Figure 11 the utility model embodiment 2 unloads the structural schematic diagram of TIP devices.
Figure number and title:1, bottom plate, 2, platform assembly, 201, reagent trough carrier, 202, EP pipe carrier, 203, adopt Blood vessel carrier, 204, the company of PCR eight EP pipe carrier, 205, TIP carriers, 206, reagent trough, 207, EP pipe support, 208, heparin tube, 209, PCR eight connects EP and manages, 210, TIP framves, 3, nucleic acid extraction component, 301,96 deep-well plates, 302, nucleic acid extraction arm, 303, First X-axis movement mechanism, the 304, first Z axis movement mechanism, the 305, first connecting plate, 306, magnetosheath frame, 307, magnetosheath, 308, Two connecting plates, 309, bar magnet frame, 310, bar magnet, 4, free liquid relief component, 401, liquid relief arm, the 402, second X-axis movement mechanism, 403, the first Y-axis movement mechanism, the 404, second Y-axis movement mechanism, the 405, second Z axis movement mechanism, 406, probe tube, 5, baffle Device, 501, baffle, 502, driving mechanism, the 503, first rotation axis, the 504, second rotation axis, 505, baffle shell, 506, One connecting rod, 507, third rotation axis, the 508, second connecting rod, 509, transmission component, 510, stepper motor, the 511, first movement Slot, the 512, second movement slots, 513, baffle circuit board, 6, waste gathering device, 601, unload TIP devices, 602, waste Slideway, 7, heating component, 701, heat block, 702, adding thermal resistance, 703, collet, 8, guided way, 9, card slot, 10, side plate, 11, elastic slice.
Specific embodiment
The utility model will be further described with reference to the accompanying drawings and examples, and the following example is only used for explaining this The utility model content of utility model is not used in the restriction protection scope of the utility model.
Embodiment 1
Referring to figs. 1 and 2, a kind of Full automatic instrument for extracting nucleic acid, including be arranged on bottom plate 1 platform assembly 2, Nucleic acid extraction component 3 and automatic liquid relief component 4, platform assembly 2 include the reagent trough carrier 201 being set on bottom plate 1, EP pipe load Frame 202, heparin tube carrier 203, PCR eight connect EP pipe carrier 204 and TIP carriers 205, and reagent trough carrier 201 is equipped with reagent Slot 206, EP pipe carrier 202 are equipped with EP pipe support 207, and heparin tube carrier 203 is equipped with heparin tube 208, and PCR eight connects EP pipe carrier 204, which are equipped with PCR eight, connects EP pipe 209, and TIP carriers 205 are equipped with TIP framves 210;Nucleic acid extraction component 3 includes several sets 96 deep-well plates 301 in 2 side of platform assembly, nucleic acid extraction component 3 further include can in 96 deep-well plates, 301 upper direction and The nucleic acid extraction arm 302 that can be gone up and down;Automatic liquid relief component 4 includes can be in 2 upper direction of nucleic acid extraction component 3 and platform assembly And the liquid relief arm 401 that can be gone up and down.
As shown in figure 3, nucleic acid extraction component 3 include set on the top of 96 deep-well plates 301 the first X-axis movement mechanism 303 with And the first Z axis movement mechanism 304 on the first X-axis movement mechanism 303, the setting of nucleic acid extraction arm 302 are moved in the first Z axis In mechanism 304;Several magnetosheath framves 306 are equipped with by the first connecting plate 305 on nucleic acid extraction arm 302, magnetosheath frame 306 is equipped with It is several it is vertical arrangement and the magnetosheath 307 in 96 deep-well plates 301 can be protruded into;The top that nucleic acid extraction arm 302 is located at magnetosheath frame 306 is logical The second connecting plate 308 is crossed equipped with several bar magnet framves 309, bar magnet frame 309 is equipped with several bar magnets that can be protruded into magnetosheath 307 310;Bar magnet frame, magnetosheath frame are divided into three groups, and every group two arranges, 8 bar magnets of each column.With use a 48 big channel bar magnet frame phases Than the advantages of bar magnet frame is divided into three groups is flexible structure, and adjusting is facilitated to install, and reduces difficulty of processing and processing cost;Bar magnet Frame, the design of magnetosheath frame corner arc avoid operator when experiment from scratching hand when inserting and taking magnetosheath, reduce operator and felt The risk of dye.
Comparative diagram 1 and Fig. 4, automatic liquid relief component 4 include the second X-axis movement mechanism set on 3 top of nucleic acid extraction component 402 and the first Y-axis movement mechanism 403 on the second X-axis movement mechanism 402, liquid relief arm 401 is moved set on the first Y-axis In mechanism 403, liquid relief arm 401 is equipped with several liquid relief units, each liquid relief unit includes being set to the second Y-axis movement mechanism The second Z axis movement mechanism 405 on 404 and the probe tube 406 being set on the second Z axis movement mechanism 405.
Referring to Fig. 5-Fig. 7, retaining device 5 is additionally provided on bottom plate 1, retaining device 5 includes being set to 96 deep-well plates, 301 top Baffle 501 and driving mechanism 502, one end of baffle 501 be equipped with the first rotation axis 503 and the second rotation axis of parallel arrangement 504, distance of first rotation axis 503 apart from 501 edge of baffle is less than the second rotation axis 504 at a distance from 501 edge of baffle;It drives Motivation structure 502 includes baffle shell 505, and the first rotation axis 503 passes through baffle shell 505 and is connected with the by first connecting rod 506 Three rotation axis 507, the second rotation axis 504 are connected with by the second connecting rod 508 across baffle shell 505 and are able to drive second Rotation axis 504 makees the transmission component 509 of circular motion;The input terminal of transmission component 509 is equipped with stepper motor 510, baffle shell The first movement slots 511 for the movement of the first rotation axis 503 are offered on 505, the lower section of the first movement slots 511, which is equipped with, supplies second The radian of the second movement slots 512 that rotation axis 504 moves, the second movement slots 512 is greater than the first movement slots 511, when the second rotation The height of first rotation axis 503 is identical as the second rotation axis 504 when axis 504 moves to the highest point of the second movement slots 512;Gear The baffle circuit board 513 connecting with stepper motor 510 is additionally provided in plate shell 505.
Waste gathering device 6 is additionally provided on bottom plate 1, waste gathering device 6 includes that auxiliary liquid relief arm 401 will be discarded TIP removed from probe tube 406 unload TIP devices 601, as depicted in figs. 1 and 2, unload TIP devices 601 be fixed on Plate structure on bottom plate, top deflect to form the pawl that falls off to liquid relief arm direction, when then probe tube abutting falls off pawl Moving up can be such that discarded TIP head falls;That unloads TIP devices 601 is arranged right below waste slideway 602, waste slideway 602 bottom is equipped with discarded TIP external dustbins, and discarded TIP fallen off are collected, avoids polluting.
Such as Fig. 8, the lower section of 96 deep-well plates 301 is equipped with several heating components 7, and heating component 7 includes heat block 701, heating The lower section of block 701 is equipped with adding thermal resistance 702, collet 703 is equipped between adding thermal resistance 702 and bottom plate 1, each rest area includes Independent heating device meets during nucleic acid extraction different step to the demand for heat of reagent.Heat block is processed using brass, Corner arc design, avoids operator and scratches the infected risk of gloves when taking consumptive material, built-in adding thermal resistance has heat The advantages that conduction efficiency is fast at high speed, is spaced between heat block and platform with collet, and collet uses PEEK material, is had The advantages that heat resistance is high, and machinability is strong, anticorrosive.
As shown in figure 9, EP pipe carrier 202 is equipped with the guided way 8 of several parallel arrangements, the bottom of EP pipe support 207 is equipped with The card slot 9 cooperated with guided way 8 is conveniently taken using the design of drawing and pulling type slideway structure, and EP pipe support 207 is polyformaldehyde material system At polyformaldehyde material has self-lubricating function, reduces the abrasion in draw process to carrier.As shown in Figure 10, TIP carriers 205 surrounding is coated with side plate 10, avoids the contaminated risk of clean TIP, and TIP 205 top surfaces of carrier are equipped with several TIP framves 210 are connected to the elastic slice 11 on TIP carriers 205, effectively block steady TIP frame, liquid relief arm is made to pick up TIP head When TIP framves be not taken up.
Lighting system, ultraviolet sterilization system and the control system for controlling various components are also equipped on bottom plate 1 (being not drawn into attached drawing).
The utility model has both the dual function of liquid relief formula and magnetic bar type, and instrument internal includes the channel 1-8 independent-lifting The high-intensitive bar magnet of liquid relief arm and the channel 1-48, reagents slot, centrifuge tube, 96 deep-well plates, PCR eight connect the consumption such as EP pipe, magnetosheath Material can carry out the movements such as the automation transfer, suction, concussion of liquid and magnetic bead, thus realize sample preparation link completely from Dynamicization operation.
Embodiment 2
As shown in figure 11, the present embodiment the difference from embodiment 1 is that:
The TIP devices 601 that unload of the present embodiment are to be installed on liquid relief arm to move back TIP first speed piece, when liquid relief unit drives Probe tube moves up, and when being moved to the position for moving back TIP first speed piece for TIP, discarded TIP head can take off automatically from probe tube It falls, then falls into the waste slideway of lower section.Relative to embodiment 1, its course of work is more flexible.
The course of work of the utility model is as follows:
Firstly, from preparation, by reagent, biological sample, TIP, 96 deep-well plates, PCR eight connect EP pipe etc. be placed on it is corresponding Position;
Then, automatic pipetting device installs TIP automatically, and successively by the reagent trough in platform mould group reagent and blood sampling Biological sample in pipe is added in the deep-well plates on nucleic acid extraction platform, automatic nucleic acid-extracting apparatus complete nucleic acid extraction and Purifying;
Subsequently, the nucleic acid extracted is transferred to the PCR eight being placed in ice chest and connected in EP pipe by automatic pipetting device;
Finally, all waste object is collected into automatically in external dustbin, and then complete the full-automatic nucleic acid extraction of whole process.
In conclusion the preferred embodiment of only the utility model, does not limit the protection scope of the utility model with this, it is all Equivalent changes and modifications made according to the scope of the patent of the utility model and the content of the manual are all what the utility model patent covered Within the scope of.

Claims (10)

1. a kind of Full automatic instrument for extracting nucleic acid, it is characterised in that:Platform assembly (2), nucleic acid including being arranged on bottom plate (1) mention Component (3) and automatic liquid relief component (4) are taken, the platform assembly is for placing various reagents and container, the reagent and container Position on the bottom plate (1) can be freely combined, and the nucleic acid extraction component (3) is used for magnetic-type nucleic acid extraction, described Automatic liquid relief component (4) is for the accurate liquid transfer between the platform assembly (2) and the nucleic acid extraction component (3).
2. a kind of Full automatic instrument for extracting nucleic acid according to claim 1, it is characterised in that:The platform assembly (2) includes Reagent trough carrier (201), EP pipe carrier (202), heparin tube carrier (203), the PCR eight being set on the bottom plate (1) connect EP Pipe carrier (204) and TIP carriers (205), the reagent trough carrier (201) are equipped with reagent trough (206), the EP pipe carrier (202) EP pipe support (207) are equipped with, the heparin tube carrier (203) is equipped with heparin tube (208), and the PCR eight connects EP pipe and carries Frame (204) is equipped with PCR eight and connects EP pipe (209), and the TIP carrier (205) is equipped with TIP framves (210).
3. a kind of Full automatic instrument for extracting nucleic acid according to claim 1, it is characterised in that:The nucleic acid extraction component (3) Including 96 deep-well plates (301) being set on the bottom plate (1), the first X-axis fitness machine being set to above 96 deep-well plates (301) Structure (303), be set to the first X-axis movement mechanism (303) on the first Z axis movement mechanism (304) and be set to the first Z Nucleic acid extraction arm (302) on shaft movement mechanism (304);It is set on the nucleic acid extraction arm (302) by the first connecting plate (305) There are several magnetosheath framves (306), the magnetosheath frame (306) is equipped with several vertical arrangements and can protrude into 96 deep-well plates (301) Interior magnetosheath (307);The top that the nucleic acid extraction arm (302) is located at the magnetosheath frame (306) passes through the second connecting plate (308) Equipped with several bar magnet framves (309), the bar magnet frame (309) is equipped with several bar magnets that can be protruded into the magnetosheath (307) (310)。
4. a kind of Full automatic instrument for extracting nucleic acid according to claim 3, it is characterised in that:It is additionally provided on the bottom plate (1) Retaining device (5), the retaining device (5) include the baffle (501) above 96 deep-well plates (301), the baffle (501) one end is equipped with the first rotation axis (503) and the second rotation axis (504) of parallel arrangement, first rotation axis (503) Distance apart from the baffle (501) edge is less than second rotation axis (504) at a distance from the baffle (501) edge; One end of first rotation axis (503) and second rotation axis (504) is connected with for driving the baffle (501) to overturn Driving mechanism (502), the driving mechanism (502) can overturn to the surface of 96 deep-well plates (301).
5. a kind of Full automatic instrument for extracting nucleic acid according to claim 4, it is characterised in that:Driving mechanism (502) packet It includes baffle shell (505), first rotation axis (503) passes through the baffle shell (505) and connected by first connecting rod (506) Have third rotation axis (507), second rotation axis (504) passes through the baffle shell (505) and passes through the second connecting rod (508) It is connected with and is able to drive the transmission component (509) that second rotation axis (504) makees circular motion;The transmission component (509) Input terminal be equipped with stepper motor (510), offer on the baffle shell (505) and moved for first rotation axis (503) The first movement slots (511), the lower sections of first movement slots (511) is equipped with for second rotation axis (504) movement The radian of two movement slots (512), second movement slots (512) is greater than first movement slots (511), when second rotation The height and described second of first rotation axis (503) described in when axis (504) moves to the highest point of second movement slots (512) Rotation axis (504) is identical;The baffle circuit being electrically connected with the stepper motor (510) is additionally provided in the baffle shell (505) Plate (513).
6. a kind of Full automatic instrument for extracting nucleic acid according to claim 1, it is characterised in that:The automatic liquid relief component (4) Including the second X-axis movement mechanism (402) being set to above the nucleic acid extraction component (3) and it is set to second X-axis movement The first Y-axis movement mechanism (403) in mechanism (402), the liquid relief arm (401) are set to the first Y-axis movement mechanism (403) On, the liquid relief arm (401) is equipped with several liquid relief units, each described liquid relief unit includes the second Y-axis movement mechanism (404), be set to the second Y-axis movement mechanism (404) on the second Z axis movement mechanism (405) and be set to the 2nd Z Probe tube (406) on shaft movement mechanism (405).
7. a kind of Full automatic instrument for extracting nucleic acid according to claim 6, it is characterised in that:It is additionally provided on the bottom plate (1) Waste gathering device (6), the waste gathering device (6) include auxiliary liquid relief arm (401) by discarded TIP head from described What is removed on probe tube (406) unloads TIP devices (601);The waste that is arranged right below for unloading TIP devices (601) is slided Road (602), the bottom of the waste slideway (602) are equipped with discarded TIP storage devices.
8. a kind of Full automatic instrument for extracting nucleic acid according to claim 3, it is characterised in that:96 deep-well plates (301) Lower section is equipped with several heating components (7), and the heating component (7) includes heat block (701), the lower section of the heat block (701) Equipped with adding thermal resistance (702), collet (703) are equipped between the adding thermal resistance (702) and the bottom plate (1).
9. a kind of Full automatic instrument for extracting nucleic acid according to claim 2, it is characterised in that:On the EP pipe carrier (202) Guided way (8) equipped with several parallel arrangements, the bottom of the EP pipe support (207) are equipped with the card cooperated with the guided way (8) Slot (9), the EP pipe support (207) are made of polyformaldehyde material.
10. a kind of Full automatic instrument for extracting nucleic acid according to claim 2, it is characterised in that:The TIP carrier (205) Surrounding be coated with side plate (10), the TIP carrier (205) if top surface be equipped with capable person described in TIP framves (210) be connected to institute State the elastic slice (11) on TIP carriers (205).
CN201820181113.XU 2018-02-01 2018-02-01 Full automatic instrument for extracting nucleic acid Active CN208151343U (en)

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CN201820181113.XU CN208151343U (en) 2018-02-01 2018-02-01 Full automatic instrument for extracting nucleic acid

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Application Number Priority Date Filing Date Title
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108048302A (en) * 2018-02-01 2018-05-18 北京同立创辉仪器有限公司 Full automatic instrument for extracting nucleic acid

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108048302A (en) * 2018-02-01 2018-05-18 北京同立创辉仪器有限公司 Full automatic instrument for extracting nucleic acid
CN108048302B (en) * 2018-02-01 2024-03-19 北京同立创辉仪器有限公司 Full-automatic nucleic acid extractor

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