CN208136266U - A kind of dedicated culture mechanism of cell climbing sheet and cell culture system - Google Patents
A kind of dedicated culture mechanism of cell climbing sheet and cell culture system Download PDFInfo
- Publication number
- CN208136266U CN208136266U CN201820262497.8U CN201820262497U CN208136266U CN 208136266 U CN208136266 U CN 208136266U CN 201820262497 U CN201820262497 U CN 201820262497U CN 208136266 U CN208136266 U CN 208136266U
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- Prior art keywords
- slide
- cell
- climbing sheet
- cell climbing
- mounting groove
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Abstract
The utility model provides a kind of dedicated culture mechanism of cell climbing sheet and cell culture system, belongs to biological study technical field.It includes substrate, mounting groove is offered on substrate, the side of mounting groove has opening, multiple slide luggage carriers are slidably mounted in mounting groove, multiple slide luggage carriers can slide into or skid off mounting groove towards the direction of opening, multiple slide locating slots are offered on slide luggage carrier, cell glass slide is provided in multiple slide locating slots, and slide locating slot is equipped with cell glass slide.The cell culture system, structure are simple and easy to use.
Description
Technical field
The utility model relates to biological study technical fields, in particular to a kind of dedicated culture mechanism of cell climbing sheet
And cell culture system.
Background technique
It uses the cell of in vitro culture that can exclude the influence of many disturbing factors of experiment in vivo as research object, applies
Various processing factors handle culture cell and are also become easy, meanwhile, cell is carried out using various technology and methods
Observation and analysis are also more convenient.Therefore, cell culture technology is the important of the life sciences such as biology, preclinical medicine research
One of technology.
With going deep into for research, cell research method and cell detection index are increasingly enriched, to the thin of in vitro culture preparation
The demand of born of the same parents and cell climbing sheet is gradually increased；Meanwhile the objectivity in order to guarantee experimental result, it is often necessary in identical condition
Under prepare cell and cell climbing sheet, make that cell quality is uniform, favourable identity, comparativity had more between experimental result.
But at present this field use method have the defects that it is different degrees of.Usual way is that multiple cells are climbed
Piece is placed directly within culture dish bottom, after cell culture, the cell of cell climbing sheet and culture dish bottom growth is collected, for different
Research method and different Indexs measures.But this method has the disadvantage that：1. cell climbing sheet is easy in smooth culture dish
Bottom sliding and overlapping, prevent growth conditions of the cell on cell climbing sheet from unifying；2. in order to reduce the weight between cell climbing sheet
Folded, cell climbing sheet needs are scattered, meanwhile, cell climbing sheet occupies a part of culture dish bottom, therefore, the cell of preparation and thin
Born of the same parents' creep plate is all few, it is difficult to meet experiment needs；3. can be directly adhered to the contact of culture dish bottom, cell due to cell climbing sheet
The back side of cell climbing sheet causes cell in the two-sided growth of cell climbing sheet, influences observation and subsequent experimental processing；4. cell climbing sheet is straight
It connects and is placed in culture dish bottom cell climbing sheet is caused tightly to be combined with bottom, be difficult to separate, cell climbing sheet clamping is extremely difficult.
Also the method having is culture dish bottom to be produced to multiple orderly slots, or place in culture dish with multiple orderly slots
Slide glass plate, these slots can grow cell or accommodate cell climbing sheet.In this way, cell and cell climbing sheet can be prepared simultaneously,
Part solves the problems, such as cell climbing sheet sliding and overlapping.But there is also following deficiencies：1. prepared cell and cell is climbed
Piece quantity is also limited；2. cell climbing sheet is since the back side and culture dish bottom or slide glass plate directly contact, cell equally can two-sided growth；
3. cell climbing sheet is small and light, adds the slot where may being rushed out when culture solution or float, it is also possible to generate creep plate
The problem of overlapping and cell growth unevenness；Similarly cell is caused to be climbed 4. cell climbing sheet is placed directly on culture dish bottom or slide glass plate
Piece clamping is difficult.Therefore, the benefit of this method is few, and practical significance is not too much big.
In addition, when being tested with cell climbing sheet, due to individually to handle each cell climbing sheet, more wasteful experiment
Material and reagent；Cell climbing sheet size is typically small, picks and places, transfer, observation etc. must concentrate, and operation is careful, prevent from falling,
Be caught broken, overturn front and back sides etc., experimental implementation process is complicated, and difficulty is larger, time and effort consuming；When the cell climbing sheet storage of preparation, it is
It prevents overlapping, overturning, scratch, often need special storing unit, also increase experimental cost.Therefore, these problems also need
It solves.
Utility model content
The utility model provides a kind of dedicated culture mechanism of cell climbing sheet, it is intended to it is special to solve cell climbing sheet in the prior art
The above problem existing for culture mechanism.
What the utility model embodiment was realized in：
A kind of dedicated culture mechanism of cell climbing sheet, the dedicated culture mechanism of cell climbing sheet includes substrate, on the substrate
Mounting groove is offered, the side of the mounting groove has opening, is slidably mounted with multiple slide loadings in the mounting groove
Frame, multiple slide luggage carriers can slide into or skid off the mounting groove, the slide loading towards the direction of the opening
Multiple slide locating slots are offered on frame, and cell glass slide, the slide positioning are provided in multiple slide locating slots
Slot is equipped with the cell glass slide.
As a kind of optimal technical scheme of the utility model, the cell glass slide includes slide ontology, slide connection
Bar and slide clamp bar, and the slide connecting rod is connect with the slide ontology, slide clamping bar respectively, the slide
Ontology is in the same plane with the slide connecting rod, and the slide clamping bar is arranged in obtuse angle with the slide connecting rod.
As a kind of optimal technical scheme of the utility model, the slide locating slot has integrally formed groove, company
It connects road and sets piece port, the groove is connected to the interface channel, and the interface channel is connected to the piece port of setting,
The depth of the groove is higher than the depth of the interface channel, and the depth of the interface channel is higher than the depth for setting piece port
Degree.
As a kind of optimal technical scheme of the utility model, parallel interval is set multiple slide luggage carriers between any two
It sets, the axial direction of the slide luggage carrier is consistent with the opening direction.
As a kind of optimal technical scheme of the utility model, multiple slide locating slots are along the slide luggage carrier
Axial direction is arranged, and is parallel to each other between multiple slide locating slots and spacing is equal.
As a kind of optimal technical scheme of the utility model, multiple sliding rails are provided in the mounting groove, it is multiple described
Sliding rail extends along the opening direction, is parallel to each other between multiple sliding rails and spacing is identical.
As a kind of optimal technical scheme of the utility model, the is separately installed on opposite two inner walls of the sliding rail
One latch and the second latch are separately installed with the first fixture block and the second fixture block on opposite two sides of the slide luggage carrier,
The first latching tooth is engaged with first fixture block, and second latch is engaged with second fixture block.
As a kind of optimal technical scheme of the utility model, the slide luggage carrier has mainboard, pacifies on the mainboard
Equipped with the first support plate and the second support plate, first support plate, second support plate are separately mounted to adjacent described
In sliding rail.
As a kind of optimal technical scheme of the utility model, first support plate, second support plate are pacified respectively
On two opposite sides of the mainboard.
A kind of cell culture system, the cell culture system include the dedicated culture mechanism of above-described cell climbing sheet.
The utility model has the beneficial effects that：
The utility model provides a kind of dedicated culture mechanism of cell climbing sheet comprising and substrate offers mounting groove on substrate,
The side of mounting groove has opening, is slidably mounted with multiple slide luggage carriers in mounting groove, multiple slide luggage carriers can
Mounting groove is slided into or skidded off towards the direction of opening, and multiple slide locating slots, multiple slide positioning are offered on slide luggage carrier
Cell glass slide is provided in slot, slide locating slot is equipped with cell glass slide；It is multiple due to being provided in mounting groove
Sliding rail, multiple sliding rails extend along opening direction, are parallel to each other between multiple sliding rails and spacing is identical, and in two relatively of sliding rail
It is separately installed with first latching tooth and the second latch on wall, is separately installed with the first fixture block on opposite two sides of slide luggage carrier
With the second fixture block, first latching tooth is engaged with the first fixture block, and the second latch is engaged with the second fixture block, and therefore, which can
To realize by the engaging of first latching tooth and the first fixture block, engaging for the second latch and the second fixture block and slide into or skid off installation
In slot, thus convenient for taking out cell glass slide out of slide locating slot, for used in experiment.Simultaneously as slide positions
Slot has integrally formed groove, interface channel and sets piece port, and groove is connected to interface channel, and interface channel leads to piece is set
Mouth connection, the depth of groove are higher than the depth of interface channel, and the depth of interface channel is higher than the depth for setting piece port, and cell carries
Slide includes that slide ontology, slide connecting rod and slide clamping bar, slide connecting rod clamp bar with slide ontology, slide respectively
Connection, slide ontology are in the same plane with slide connecting rod, and slide clamping bar is arranged in obtuse angle with slide connecting rod, because
This, which can be equipped with slide locating slot, it preferably fits on slide locating slot, meanwhile, work as needs
When cell glass slide is taken out from slide locating slot, slide clamping bar can be directly clamped, without contacting slide sheet
Cell on body, to avoid direct contact with cell and the case where damaging cell occur.It follows that the dedicated training of the cell climbing sheet
It is simple and easy to use to support mechanism structure.
The cell culture system that the utility model obtains by above-mentioned design, the cell culture system is due to having above
The dedicated culture mechanism of cell climbing sheet, has the characteristics that structure is simple and easy to use.
Detailed description of the invention
It, below will be to required in embodiment in order to illustrate more clearly of the technical solution of the utility model embodiment
The attached drawing used is briefly described, it should be understood that the following drawings illustrates only some embodiments of the utility model, therefore not
It should be considered as the restriction to range, for those of ordinary skill in the art, without creative efforts,
It can also be obtained according to these attached drawings other relevant attached drawings.
Fig. 1 is the dedicated culture mechanism structural schematic diagram of cell climbing sheet provided by the embodiment of the utility model；
Fig. 2 is installation slot structure schematic diagram provided by the embodiment of the utility model；
Fig. 3 is slide goods rack structure schematic diagram provided by the embodiment of the utility model；
Fig. 4 is cell slide configurations schematic diagram provided by the embodiment of the utility model；
Fig. 5 is slide positioning slot structure schematic diagram provided by the embodiment of the utility model.
Icon：The dedicated culture mechanism of 1- cell climbing sheet；2- substrate；3- mounting groove；4- opening；5- slide luggage carrier；6- glass
Piece locating slot；7- slide ontology；8- slide connecting rod；9- slide clamps bar；10- groove；11- interface channel；It is logical that 12- sets piece
Mouthful；13- sliding rail；14- first latching tooth；The second latch of 15-；The first fixture block of 16-；The second fixture block of 17-；18- mainboard；19- first
Fagging；The second support plate of 20-.
Specific embodiment
It is practical below in conjunction with this to keep the purposes, technical schemes and advantages of the utility model embodiment clearer
The technical solution in the utility model embodiment is clearly and completely described in attached drawing in novel embodiment, shows
So, described embodiment is a part of embodiment of the utility model, rather than whole embodiments.It is practical based on this
Embodiment in novel, it is obtained by those of ordinary skill in the art without making creative efforts every other
Embodiment is fallen within the protection scope of the utility model.Therefore, the implementation to the utility model provided in the accompanying drawings below
The detailed description of mode is not intended to limit the range of claimed invention, but is merely representative of the utility model
Selected embodiment.
In the description of the present invention, it should be understood that indicating position or the term of positional relationship are based on attached drawing
Shown in orientation or positional relationship, be merely for convenience of describing the present invention and simplifying the description, rather than indication or suggestion institute
The element of finger must have a particular orientation, be constructed and operated in a specific orientation, therefore should not be understood as to the utility model
Limitation.
In the present invention unless specifically defined or limited otherwise, term " installation ", " connected ", " connection ", " Gu
It is fixed " etc. terms shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or integral；It can be
Mechanical connection, is also possible to be electrically connected；It can be directly connected, two can also be can be indirectly connected through an intermediary
The interaction relationship of connection or two elements inside element.It for the ordinary skill in the art, can basis
Concrete condition understands the concrete meaning of above-mentioned term in the present invention.
In the present invention unless specifically defined or limited otherwise, fisrt feature is on or below second feature
It may include that the first and second features directly contact, also may include that the first and second features are not direct contacts but pass through it
Between other characterisation contact.Moreover, fisrt feature is on second feature, top and above include fisrt feature the
Right above two features and oblique upper, or first feature horizontal height is merely representative of higher than second feature.Fisrt feature is in the second spy
Under sign, lower section and fisrt feature included below be directly below and diagonally below the second feature, or be merely representative of fisrt feature level
Height is less than second feature.
Embodiment：
A kind of cell culture system is present embodiments provided, is mainly used for that cell climbing sheet is added in Tissue Culture Dish,
After growing cell on creep plate, creep plate is taken out, then the cell on creep plate is handled, including flushing, fixation, antibody
Be incubated for and etc..
Cell culture system includes the dedicated culture mechanism 1 of cell climbing sheet, is trained by the dedicated culture mechanism 1 of the cell climbing sheet
Support cell.
In the present embodiment, Fig. 1 to Fig. 5 is please referred to, the dedicated culture mechanism 1 of cell climbing sheet includes substrate 2, is opened on substrate 2
Equipped with mounting groove 3, the side of mounting groove 3 has opening 4, is slidably mounted with multiple slide luggage carriers 5 in mounting groove 3, more
A slide luggage carrier 5 can slide into or skid off mounting groove 3 towards the direction of opening 4, and multiple slides are offered on slide luggage carrier 5
Locating slot 6 is provided with cell glass slide in multiple slide locating slots 6, and slide locating slot 6 is equipped with cell glass slide.
Further, in the present embodiment, cell glass slide includes slide ontology 7, slide connecting rod 8 and slide clamping
Bar 9, slide connecting rod 8 are connect with slide ontology 7, slide clamping bar 9 respectively, and slide ontology 7 is in same with slide connecting rod 8
In plane, slide clamping bar 9 is arranged in obtuse angle with slide connecting rod 8.
Further, in the present embodiment, slide locating slot 6 have integrally formed groove 10, interface channel 11 and
Piece port 12 is set, groove 10 is connected to interface channel 11, and interface channel 11 is connected to piece port 12 is set, and the depth of groove 10 is higher than
The depth of interface channel 11, the depth of interface channel 11 are higher than the depth for setting piece port 12.
Therefore, which can be equipped with slide locating slot 6, preferably fit on slide locating slot 6,
Meanwhile when needing to take out cell glass slide from slide locating slot 6, slide clamping bar 9 can be directly clamped, without
The cell on slide ontology 7 is contacted, to avoid direct contact with cell and the case where damaging cell occur.It follows that should
Dedicated 1 structure of culture mechanism of cell climbing sheet is simple and easy to use.
It should be noted that in the present embodiment, parallel interval is arranged multiple slide luggage carriers 5 between any two, and slide carries
The axial direction of rack 5 is consistent with 4 directions of opening.
It should be noted that in the present embodiment, multiple slide locating slots 6 are arranged along the axial direction of slide luggage carrier 5
It is arranged, is parallel to each other between multiple slide locating slots 6 and spacing is equal.
Further, in the present embodiment, slide luggage carrier 5 has mainboard 18, is equipped with the first support plate on mainboard 18
19 and second support plate 20, the first support plate 19, the second support plate 20 are separately mounted in adjacent sliding rail 13.Meanwhile first
Support plate 19, the second support plate 20 are separately mounted on two opposite sides of mainboard 18.
Further, in the present embodiment, multiple sliding rails 13 are provided in mounting groove 3, multiple sliding rails 13 are along 4 directions that are open
Extend, is parallel to each other between multiple sliding rails 13 and spacing is identical.
Further, in the present embodiment, first latching tooth 14 and the are separately installed on opposite two inner walls of sliding rail 13
The first fixture block 16 and second is separately installed on opposite two sides of two latches 15, the first support plate 19 and the second support plate 20
Fixture block 17, first latching tooth 14 are engaged with the first fixture block 16, and the second latch 15 is engaged with the second fixture block 17, therefore, the slide loading
Frame 5 can realize cunning by the engaging of first latching tooth 14 and the first fixture block 16, engaging for the second latch 15 and the second fixture block 17
Into or skid off in mounting groove 3, thus convenient for taking out cell glass slide out of slide locating slot 6, for used in experiment.
It is climbed it should be noted that being provided in the dedicated culture mechanism 1 of the cell climbing sheet and can turn on or off the cell
Entire cell culture system, can so be directly placed in incubator and cultivate by the lid of the dedicated culture mechanism 1 of piece.
In conclusion the utility model provides a kind of dedicated culture mechanism 1 of cell climbing sheet comprising substrate 2, on substrate 2
Mounting groove 3 is offered, the side of mounting groove 3 has opening 4, is slidably mounted with multiple slide luggage carriers 5 in mounting groove 3,
Multiple slide luggage carriers 5 can slide into or skid off mounting groove 3 towards the direction of opening 4, and multiple glass are offered on slide luggage carrier 5
Piece locating slot 6, cell glass slide is provided in multiple slide locating slots 6, and slide locating slot 6 is set with the cooperation of cell glass slide
It sets；Due to being provided with multiple sliding rails 13 in mounting groove 3, multiple sliding rails 13 extend along 4 directions of opening, between multiple sliding rails 13 mutually
Parallel and spacing is identical, and is separately installed with first latching tooth 14 and the second latch 15 on opposite two inner walls of sliding rail 13, slide
The first fixture block 16 and the second fixture block 17, first latching tooth 14 and the first fixture block are separately installed on opposite two sides of luggage carrier 5
16 engagements, the second latch 15 are engaged with the second fixture block 17, and therefore, which can pass through first latching tooth 14 and first
The engagement of fixture block 16, the second latch 15 and the second fixture block 17 engage to realize and slide into or skid off in mounting groove 3, are thus convenient for
Cell glass slide is taken out out of slide locating slot 6, for used in experiment.Simultaneously as slide locating slot 6 have one at
The groove 10 of type, interface channel 11 and piece port 12 is set, groove 10 is connected to interface channel 11, interface channel 11 and to set piece logical
Mouth 12 is connected to, and the depth of groove 10 is higher than the depth of interface channel 11, and the depth of interface channel 11 is higher than the depth for setting piece port 12
Degree, and cell glass slide include slide ontology 7, slide connecting rod 8 and slide clamping bar 9, slide connecting rod 8 respectively with slide
Ontology 7, slide clamping bar 9 connect, and slide ontology 7 is in the same plane with slide connecting rod 8, and slide clamps bar 9 and slide
Connecting rod 8 is arranged in obtuse angle, and therefore, which can be equipped with slide locating slot 6, preferably fits in slide
On locating slot 6, meanwhile, when needing to take out cell glass slide from slide locating slot 6, it can directly clamp slide clamping
Bar 9, without contacting the cell on slide ontology 7, to avoid direct contact with cell and the case where damaging cell occur.By
This is it is found that dedicated 1 structure of culture mechanism of the cell climbing sheet is simple and easy to use.The cell culture system is due to having above
The dedicated culture mechanism 1 of cell climbing sheet, has the characteristics that structure is simple and easy to use.
Above description is merely a prefered embodiment of the utility model, is not intended to limit the utility model, for
For those skilled in the art, various modifications and changes may be made to the present invention.All spirit and original in the utility model
Within then, any modification, equivalent replacement, improvement and so on be should be included within the scope of protection of this utility model.
Claims (10)
1. a kind of dedicated culture mechanism of cell climbing sheet, which is characterized in that the dedicated culture mechanism of cell climbing sheet includes substrate, institute
It states and offers mounting groove on substrate, the side of the mounting groove has opening, is slidably mounted in the mounting groove multiple
Slide luggage carrier, multiple slide luggage carriers can slide into or skid off the mounting groove towards the direction of the opening, described
Multiple slide locating slots are offered on slide luggage carrier, are provided with cell glass slide in multiple slide locating slots, it is described
Slide locating slot is equipped with the cell glass slide.
2. the dedicated culture mechanism of cell climbing sheet according to claim 1, which is characterized in that the cell glass slide includes glass
Piece ontology, slide connecting rod and slide clamp bar, and the slide connecting rod is clamped with the slide ontology, the slide respectively
Bar connection, the slide ontology are in the same plane with the slide connecting rod, and the slide clamping bar and the slide connect
Extension bar is arranged in obtuse angle.
3. the dedicated culture mechanism of cell climbing sheet according to claim 2, which is characterized in that the slide locating slot has one
Body formed groove, interface channel and piece port is set, the groove is connected to the interface channel, the interface channel and institute
It states and sets the connection of piece port, the depth of the groove is higher than the depth of the interface channel, and the depth of the interface channel is higher than institute
State the depth for setting piece port.
4. the dedicated culture mechanism of cell climbing sheet according to claim 3, which is characterized in that multiple slide luggage carriers two
Parallel interval is arranged between two, and the axial direction of the slide luggage carrier is consistent with the opening direction.
5. the dedicated culture mechanism of cell climbing sheet according to claim 4, which is characterized in that multiple slide locating slot edges
The axial direction of the slide luggage carrier is arranged, and is parallel to each other between multiple slide locating slots and spacing is equal.
6. the dedicated culture mechanism of cell climbing sheet according to claim 5, which is characterized in that be provided in the mounting groove more
A sliding rail, multiple sliding rails extend along the opening direction, are parallel to each other between multiple sliding rails and spacing is identical.
7. the dedicated culture mechanism of cell climbing sheet according to claim 6, which is characterized in that in two relatively of the sliding rail
It is separately installed with first latching tooth and the second latch on wall, is separately installed with first on opposite two sides of the slide luggage carrier
Fixture block and the second fixture block, the first latching tooth are engaged with first fixture block, and second latch is engaged with second fixture block.
8. the dedicated culture mechanism of cell climbing sheet according to claim 7, which is characterized in that the slide luggage carrier has master
Plate is equipped with the first support plate and the second support plate on the mainboard, and first support plate, second support plate are pacified respectively
In the adjacent sliding rail.
9. the dedicated culture mechanism of cell climbing sheet according to claim 8, which is characterized in that first support plate, described
Second support plate is separately mounted on two opposite sides of the mainboard.
10. a kind of cell culture system, which is characterized in that the cell culture system includes described in claim any one of 1-9
The dedicated culture mechanism of cell climbing sheet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820262497.8U CN208136266U (en) | 2018-02-22 | 2018-02-22 | A kind of dedicated culture mechanism of cell climbing sheet and cell culture system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820262497.8U CN208136266U (en) | 2018-02-22 | 2018-02-22 | A kind of dedicated culture mechanism of cell climbing sheet and cell culture system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208136266U true CN208136266U (en) | 2018-11-23 |
Family
ID=64285881
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201820262497.8U Expired - Fee Related CN208136266U (en) | 2018-02-22 | 2018-02-22 | A kind of dedicated culture mechanism of cell climbing sheet and cell culture system |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN208136266U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114369536A (en) * | 2022-02-24 | 2022-04-19 | 中南大学湘雅医院 | Cell climbing sheet culture device and application method thereof |
| JP7286749B1 (en) | 2021-12-23 | 2023-06-05 | 財團法人工業技術研究院 | Cell and tissue sheet forming package and cell injection device |
-
2018
- 2018-02-22 CN CN201820262497.8U patent/CN208136266U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7286749B1 (en) | 2021-12-23 | 2023-06-05 | 財團法人工業技術研究院 | Cell and tissue sheet forming package and cell injection device |
| CN114369536A (en) * | 2022-02-24 | 2022-04-19 | 中南大学湘雅医院 | Cell climbing sheet culture device and application method thereof |
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| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
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| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20181123 Termination date: 20190222 |