CN208130251U - A kind of external diaphragm pacemaker of the medium frequency electric stimulation of low frequency modulations - Google Patents
A kind of external diaphragm pacemaker of the medium frequency electric stimulation of low frequency modulations Download PDFInfo
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- CN208130251U CN208130251U CN201720491939.1U CN201720491939U CN208130251U CN 208130251 U CN208130251 U CN 208130251U CN 201720491939 U CN201720491939 U CN 201720491939U CN 208130251 U CN208130251 U CN 208130251U
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Abstract
The utility model discloses a kind of external diaphragm pacemakers of the medium frequency electric stimulation of low frequency modulations, it includes low frequency modulations circuit, amount of bias adjustment circuit, voltage amplitude adjustment circuit, power amplification circuit and isolating transformer, the low frequency modulations circuit is modulated the offset signal that the analog signal to be formed is generated with amount of bias adjustment circuit to low frequency signal and is overlapped, and superimposed signal is successively adjusted voltage amplitude via voltage amplitude adjustment circuit, power amplification circuit exports treatment signal by isolating transformer again after carrying out power amplification.The utility model makes it export result as the variation of the frequency and amplitude of low frequency signal changes by low frequency modulations, amount of bias superposition, voltage amplitude adjustment, power amplification and isolating transformer, have the characteristics that low frequency, electric current of intermediate frequency and therapeutic effect, the intermediate frequency electro ultrafiltration of low frequency modulations is deeper, it is more suitable for the deeper patient of the in vitro table of the stimulation to nervus phrenicus, especially nervus phrenicus.
Description
Technical field
The utility model belongs to medical instruments field, and in particular to the low frequency modulations in the physiatrics of medical science of recovery therapy field
Medium frequency electric stimulation external diaphragm pacemaker.
Background technique
The breathing related muscles of human body mainly have diaphram, external intercostal muscles, pectoralis major, abdominal muscle, nutator etc., middle diaphragm
Flesh and external intercostal muscles are most important inspiratory muscles.When air-breathing, contraction of diaphragm, under diaphragm top will, thoracic cavity increases;When expiration, diaphram relaxes
, diaphragm top rises, and thoracic cavity reduces.Diaphram is most important respiratory muscle, and in normal respiration, the effect of contraction of diaphragm accounts for ventilatory capacity
70% to 80%, but diaphram oxygen demand is seldom, is generally less than the 20% of entire breathing muscle group oxygen demand.From angle of physiology
It sees, improving diaphragm function is not only economical but also has the respiratory movement of fine benefit to improve mode.
Green (Glenn) utility model in the U.S. in 1967 diaphragm pacemaker to implant is mainly used for chronic logical
Airway dysfunction is not complete, the respiratory paralysis as caused by the centrals lesion such as central alveolar hypoventilation syndrome, brain stem, spinal cord.It is this
The diaphragm pacemaker of implanted, electrode bury at left and right nervus phrenicus in vivo, by respiratory rhythm automatically unilateral or bilateral from body
It is outer that electric pulse stimulation nervus phrenicus is transmitted by electromagnetic coupling, achieve the purpose that improve respiratory function.Zhongshan Medical Univ. in 1987
Professors utility model external diaphragm pacemaker, and applied for patent.Chinese Patent Application No. CN87208778,
CN89200051、CN89220851、CN90109631、CN200720059728、CN200920053574、
CN201020121786, CN201220045744, CN200420105510 disclose the realization side of several external diaphragm pacemakers
Case, although implementation is different, the electrical stimulation signal of output is all low-frequency electrostimulating signal, such as:In preceding 8 patents, instrument
Device is all using low-frequency electrostimulating signal in treatment, and with 40 hertz for optimal frequency, CN200420105510 provides 40 hertz
With 2.5 hertz+40 hertz of output frequency.The Implanted type diaphragm pace-maker of U.S. Green (Glenn) utility model is also with low
Frequency output treatment signal.
In the physiatrics of medical science of recovery therapy field frequency 1000 hertz of pulse currents below be referred to as low-frequency current or
Low frequency pulse current.It is known as low frequency electrotherapy using the method that low frequency pulse current acts on human disease treatment.Applying frequency
The method of 1K~100K hertz of pulse current treatment disease is known as medium frequency electrotherapy.
Existing electrotherapy theory thinks:The frequency of electric current of intermediate frequency is higher than low-frequency electrical, and is alternating current, acts on people
The electrology characteristic and generated physical and chemical effect and low-frequency electrical that human body is showed when body are significantly different.
1. tissue resistance can be overcome, compared with low-frequency electrical, deeper tissue tissue can be applied to different frequency electricity
The resistance of stream is different, and higher to the resistance of low-frequency electrical, with increasing for power frequency, the resistance of human body is gradually reduced.In addition to electricity
It hinders other than characteristic, tissue also has the characteristic of capacitor.The higher electric current of frequency is easier to through capacitor, and medium frequency electric compares low frequency
Electricity is easy to pass through capacitor.Since human body is all lower to the resistance of the higher alternating current of frequency and capacitive reactance, total impedance is also small to be obtained
More, the electric current passed through is more.Current strength applied by medium frequency electrotherapy is larger, up to 0.1~0.5mA/cm2, can reach
Depth to tissue is also relatively deep.
2. two-way electroless effect:Electric current of intermediate frequency is the higher alternating current of frequency, is that a kind of forward direction replaces variation with negative sense
Faster electric current, point of no positive and negative anodes.When electric current of intermediate frequency acts on human body, in the positive half cycle in each period of electric current and negative half
Ion in week in tissue is all moved back and forth to different directions, thus cannot be moved on under electrode and be caused cell reaction, electricity
No soda acid product generates under extremely, and the skin under electrode will not chemical stimulation as when direct current electrotherapy by soda acid product
And it is damaged.
3. excitor nerve musculature:Though medium frequency electric is obvious not as good as low-frequency electrical to the stimulation of movement, sensory nerve,
Low-frequency electrical is but better than to the adjustment effect of autonomic nerve, viscera function, and tissue depth can be applied to, is causing strong muscle
Skin is without obvious shouting pain while contraction.When medium frequency electric acts on skin, there is no strong impulse to nervus cutaneus and receptor, with
Only slight vibratory sense when the medium frequency electric stimulation of threshold intensity, current strength only have picotement when increasing, nothing does not accommodate significantly
Pain, picotement gradually weakens when being persistently powered, and just occurs uncomfortable constraint sense when current strength is very big.Strong electric current of intermediate frequency thorn
Swashing causes feeling of feeling when contraction of muscle than low-frequency electrostimulating when comfortably much, it is not bright patient when contraction of muscle occur
The feeling of aobvious pain, therefore patient is resistant to biggish current strength when electrotherapy.
4. easing pain and promoting blood circulation:10~15 minutes after various intermediate frequency electro ultrafiltrations, the capillary vessel number of partly open
Increase, blood flow velocity and blood flow have increase, and local blood circulation improves.Medium frequency electric has inhibiting effect to sensory nerve, can
It rises dermatalgia above threshold, therefore has obvious analgesic activity.
5. the characteristics of electric current of intermediate frequency of low frequency modulations:The electric current of intermediate frequency of low frequency modulations then has the characteristics of low, electric current of intermediate frequency concurrently.
It is now recognized that the stimulation most suitable electric current of lesion muscle has not been simple low frequency pulse current but the intermediate frequency by low frequency modulations
Electric current, electric current used by it had not only contained medium frequency electric ingredient, but also had the characteristics that low-frequency electrical.And this kind of electric current does not have low-frequency electrical
The shortcomings that (such as effect table is shallow, big to skin irritatin, there is electrolysis), the advantages of but having had both low, medium frequency electric and effect.
Due to history, the external diaphragm pacemaker produced both at home and abroad at present is all low-frequency electric pulse therapeutic device.
But this low-frequency electric pulse has the shortcomings that its is intrinsic:
As stimulation table it is shallow, it is big to skin irritatin, have electrolysis, be easy to cause fatigue.The in vitro table of nervus phrenicus has one
Fixed distance, general electro photoluminescence are not easy stimulation to nervus phrenicus.The external diaphram designed in the past according to low-frequency electric pulse principle
Pacemaker, since stimulation table is shallow, nervus phrenicus is arrived in different surely good stimulation, so curative effect is not ideal enough.
Utility model content
For overcome the deficiencies in the prior art, the purpose of this utility model is to provide a kind of medium frequency electric of low frequency modulations thorns
Sharp external diaphragm pacemaker, amplitude change with the variation of the frequency and amplitude of low frequency signal, have low frequency, medium frequency electric
The intermediate frequency electro ultrafiltration of the characteristics of stream and therapeutic effect, low frequency modulations is deeper, is more suitable for the stimulation to nervus phrenicus, especially nervus phrenicus
The deeper patient of in vitro table.
The purpose of this utility model is implemented with the following technical solutions:
A kind of external diaphragm pacemaker of the medium frequency electric stimulation of low frequency modulations comprising low frequency modulations circuit, amount of bias tune
Whole circuit, voltage amplitude adjustment circuit, power amplification circuit and isolating transformer, the low frequency modulations circuit to low frequency signal into
The offset signal that the analog signal that row modulation is formed is generated with amount of bias adjustment circuit is overlapped, and superimposed signal successively passes through
Voltage amplitude is adjusted by voltage amplitude adjustment circuit, power amplification circuit passes through isolation transformation after carrying out power amplification again
Device output treatment signal.
Further, the low frequency modulations circuit is processor, after the processor is modulated low frequency signal, by institute
It states the D/A conversion module inside processor and exports modulated analog signal.
Further, the processor is STM32F103VET6.
Further, the amount of bias adjustment circuit includes zero offset circuit, resistance R148, resistance R150, resistance
R152, resistance R153 and amplifier U3, the D/A conversion module export modulated analog signal and are connected by resistance R150
To the normal phase input end of amplifier U3, the output end of zero offset circuit is also connected to the positive of amplifier U3 by resistance R148
Input terminal, the resistance R153 are connected between the inverting input terminal of amplifier U3 and the output end of amplifier U3, the resistance
One end of R152 is connected to the inverting input terminal of amplifier U3, other end ground connection, and the output end of the amplifier U3 is connected to electricity
Press the input terminal of amplitude adjusting circuit.
Further, the zero offset circuit includes negative voltage source, slide rheostat RV1, resistance R146, resistance R147
And capacitor C122, capacitor C123 and amplifier U5, wherein the negative voltage source passes sequentially through resistance R146, slide rheostat
It is grounded after RV1 and resistance R147, the sliding end of the slide rheostat is connected to the normal phase input end of amplifier U5, the amplification
The inverting input terminal of device U5 is connected with its output end, and one end of the capacitor C122 and capacitor C123 are respectively connected to amplifier U5
Inverting input terminal and amplifier U5 output end, the other end of the capacitor C122 and capacitor C123 is grounded, the amplification
The output end of device U5 is connected to the normal phase input end of amplifier U3 by resistance R148.
Further, the amount of bias adjustment circuit further includes that first voltage follows circuit and second voltage to follow circuit,
Wherein, it includes amplifier U2 and resistance R149 that the first voltage, which follows circuit, and it includes amplification that the second voltage, which follows circuit,
Device U4 and resistance R151, the D/A conversion module export modulated analog signal and are connected to amplifier U2 by resistance R149
Normal phase input end, the output end of the amplifier U2 is connected to the normal phase input end of amplifier U3 by resistance R150, described
The inverting input terminal of amplifier U2 is connected with the output end of amplifier U2, and the output end of the amplifier U3 is connected by resistance R151
It is connected to the normal phase input end of amplifier U4, the inverting input terminal of the amplifier U4 is connected with the output end of amplifier U4, described
The output end of amplifier U4 is connected to the input terminal of voltage amplitude adjustment circuit.
Further, the voltage amplitude adjustment circuit includes digital regulation resistance U6, resistance R162, resistance R163, sliding
Rheostat RV2, electrolytic capacitor C124 and capacitor C126, the high voltage input terminal of the digital regulation resistance U6 are connected by resistance R163
It is connected to the output end of amplifier U4, the increase input terminal and lifting input terminal of the digital regulation resistance U6 is respectively connected to processor
The first output end and second output terminal, ground terminal, chip select input end and the low-voltage input terminal of the digital regulation resistance U6
It is grounded, the power end of the digital regulation resistance U6 connects a positive supply, and the sliding end of the digital regulation resistance U6 passes sequentially through
It is grounded after resistance R162 and slide rheostat RV2, the cathode of the electrolytic capacitor C124 is connected to the sliding of slide rheostat RV2
End, the anode of the electrolytic capacitor C124 are connected to the input terminal of power amplification circuit, and one end of the capacitor C126 is grounded, separately
One end is connected to the anode of electrolytic capacitor C124.
Further, the digital regulation resistance U6 is X9C103S.
Further, the power amplification circuit includes amplifier U7, resistance R164, resistance R166, resistance R167, electrolysis
The normal phase input end of capacitor C125, electrolytic capacitor C130, capacitor C127 and capacitor C129, the amplifier U7 are with capacitor C126's
The anode of one end and electrolytic capacitor C124 are all connected with, the anode of the electrolytic capacitor C125 and the anode point of electrolytic capacitor C130
It is not connected to the output end of amplifier U7 and the inverting input terminal of amplifier U7, the cathode and electrolysis electricity of the electrolytic capacitor C125
The cathode of appearance C130 is respectively connected to the both ends of the armature winding of isolating transformer;After the capacitor C127 and resistance R166 series connection
One end is connected to the output end of amplifier U7, other end ground connection;Both ends difference after the capacitor C129 and resistance R164 series connection
It is connected to the output end of amplifier U7 and the inverting input terminal of amplifier U7;One end of the resistance R167 is grounded, and the other end connects
It is connected to the cathode of electrolytic capacitor C130;Output treatment signal between the both ends of the secondary windings of the isolating transformer, described
Also bridging has capacitor C128 and resistance R165 between the both ends of the secondary windings of isolating transformer.
Further, the external diaphragm pacemaker of the medium frequency electric stimulation of the low frequency modulations further includes a warning circuit, institute
State warning circuit include resistance R103, divider resistance R104, NPN triode Q24, buzzer LS1, zener diode D18 and
Positive supply, the both ends of the buzzer LS1 are respectively connected to the collector of positive supply and NPN triode Q24, two pole of pressure stabilizing
The positive and negative electrode of pipe D18 is connected to NPN triode Q24 and positive supply, and the base stage of the NPN triode Q24 passes through resistance
R103 is connected to the third output end of processor, the emitter ground connection of the NPN triode Q24, one end of the resistance R104
It is connected to the base stage of NPN triode Q24, other end ground connection.
Compared with prior art, the beneficial effects of the utility model are:
The utility model passes through low frequency modulations, amount of bias superposition, voltage amplitude adjustment, power amplification and isolating transformer
So that its export result change with the variation of the frequency and amplitude of low frequency signal, have the characteristics that low frequency, electric current of intermediate frequency and
The intermediate frequency electro ultrafiltration of therapeutic effect, low frequency modulations is deeper, and it is deeper to be more suitable for the in vitro table of the stimulation to nervus phrenicus, especially nervus phrenicus
Patient.
Detailed description of the invention
Fig. 1 is the circuit diagram of low frequency modulations circuit in the utility model;
Fig. 2 is the circuit diagram of the house dog timing circuit in the utility model;
Fig. 3 is the circuit diagram of warning circuit in the utility model;
Fig. 4 is the circuit diagram of amount of bias adjustment circuit in the utility model;
Fig. 5 is the circuit diagram of zero offset circuit in the utility model;
Fig. 6 is that the circuit of voltage amplitude adjustment circuit, power amplification circuit and isolating transformer in the utility model is former
Reason figure;
Fig. 7 is the waveform diagram of sine wave;
Fig. 8 is positive the waveform diagram of losing side wave;
Fig. 9 is the waveform diagram of positive and negative trapezoidal wave;
Figure 10 is positive the waveform diagram of negative sine wave;
Figure 11 is the waveform diagram one of positive and negative triangular wave;
Figure 12 is the waveform diagram two of positive and negative triangular wave;
Figure 13 is the waveform diagram three of positive and negative triangular wave;
Figure 14 is the waveform diagram four of positive and negative triangular wave;
Figure 15 is the waveform diagram five of positive and negative triangular wave;
Figure 16 is positive the waveform diagram of negative exponent wave;
Figure 17 be when low-frequency modulation signal be positive losing side wave, intermediate frequency be half-sine wave when, external diaphragm pacemaker output
The waveform diagram for treating signal;
Figure 18 is the waveform diagram of positive negative pulse stuffing square wave;
Figure 19 is the waveform diagram of half-sine wave;
Figure 20 is the waveform diagram of square wave;
Figure 21 is the waveform diagram of trapezoidal wave;
Figure 22 is the waveform diagram of sine wave;
Figure 23 is the waveform diagram one of triangular wave;
Figure 24 is the waveform diagram two of triangular wave;
Figure 25 is the waveform diagram three of triangular wave;
Figure 26 is the waveform diagram four of triangular wave;
Figure 27 is the waveform diagram five of triangular wave;
Figure 28 is the waveform diagram of exponential wave;
Figure 29 is that low-frequency modulation signal is square wave, when intermediate frequency is half-sine wave, the treatment letter of external diaphragm pacemaker output
Number waveform diagram;
Figure 30 is the waveform diagram of pulse square wave;
Figure 31 is that intermediate frequency is sine wave, and low-frequency modulation signal is followed successively by positive and negative square wave, positive and negative trapezoidal wave, positive and negative triangular wave
One, positive and negative exponential wave, the waveform diagram of the treatment signal of external diaphragm pacemaker output;
Figure 32 is that intermediate frequency is pulse square wave, and low-frequency modulation signal is followed successively by trapezoidal wave, square wave, triangular wave two, sine wave, refers to
Number wave, the waveform diagram of the treatment signal of external diaphragm pacemaker output;
Figure 33 is that intermediate frequency is pulse square wave and low-frequency modulation signal is trapezoidal wave, and then intermediate frequency is sine wave and low frequency modulations
Signal is positive losing side wave, and intermediate frequency is positive negative pulse stuffing square wave and low-frequency modulation signal is positive and negative triangular wave one, and intermediate frequency is half-sine wave
And low-frequency modulation signal be square wave when, external diaphragm pacemaker output treatment signal waveform diagram.
Specific embodiment
In the following, being described further in conjunction with attached drawing and specific embodiment to the utility model, it should be noted that
Under the premise of not colliding, it can be formed in any combination between various embodiments described below or between each technical characteristic new
Embodiment.
A kind of external diaphragm pacemaker of the medium frequency electric stimulation of low frequency modulations comprising low frequency modulations circuit, amount of bias tune
Whole circuit, voltage amplitude adjustment circuit, power amplification circuit and isolating transformer, low frequency modulations circuit adjust low frequency signal
The offset signal that the analog signal that system is formed is generated with amount of bias adjustment circuit is overlapped, and superimposed signal is successively via electricity
Pressure amplitude adjusting circuit is adjusted voltage amplitude, is defeated by isolating transformer again after power amplification circuit progress power amplification
Out.
It please referring to shown in Fig. 1, low frequency modulations circuit is processor U1, after processor U1 is modulated low frequency signal, by
D/A conversion module inside processor exports modulated analog signal, and processor U1 uses STM32F103VET6 single-chip microcontroller,
Its 29th pin (PA4) exports analog signal.The peripheral circuit of STM32F103VET6 single-chip microcontroller is custom circuit, for example, figure
2 be its house dog timing circuit comprising resistance R97, capacitor C82, resistance R96, resistance R98, resistance R99, capacitor C83, electricity
Hold C84, capacitor C85 and watchdog chip U8.Wherein, the both ends after resistance R97 and capacitor C82 series connection are respectively connected to 3.3V
Voltage source and ground, one end ground connection of capacitor C83, the other end is connected to 3.3V voltage source, after resistance R98 and capacitor C84 connect
Both ends be respectively connected to 3.3V voltage source and ground, the both ends after resistance R99 and capacitor C85 series connection are respectively connected to 3.3V electricity
Potential source and ground, watchdog chip U8 use SP706SEN-L (SIPEX), and hand-reset end (the 1st pin) is connected to resistance
Between R97 and capacitor C82, power end (the 2nd pin) is connected to 3.3V voltage source, ground terminal (the 3rd pin) ground connection, Power Supply Monitoring
Input terminal (the 4th pin) is grounded or connected to power end (the 2nd pin), and Power Supply Monitoring output end (the 5th pin) keeps high level,
House dog input terminal (the 6th pin) is connected to the 71st pin (end PA12) of STM32F103VET6 single-chip microcontroller, is additionally coupled to simultaneously
Between resistance R98 and capacitor C84, reset output terminal (the 7th pin) is connected to the 14th pin of STM32F103VET6 single-chip microcontroller
(end NRST), while being additionally coupled between resistance R99 and capacitor C85, house dog output end (the 8th pin) is connected by resistance R96
It is connected to hand-reset end (the 1st pin).Which is not described herein again for other peripheral circuits.
Shown in referring to figure 4., amount of bias adjustment circuit includes that first voltage follows circuit, second voltage to follow circuit, zero
Point biasing circuit, resistance R148, resistance R150, resistance R152, resistance R153 and amplifier U3, first voltage follow circuit packet
Amplifier U2 and resistance R149 are included, it includes that amplifier U4 and the output of resistance R151, D/A conversion module are adjusted that second voltage, which follows circuit,
Analog signal after system is connected to the normal phase input end of amplifier U2 by resistance R149, and the output end of amplifier U2 passes through resistance
R150 is connected to the normal phase input end of amplifier U3, and the inverting input terminal of amplifier U2 is connected with the output end of amplifier U2, and zero
The output end of point biasing circuit is also connected to the normal phase input end of amplifier U3 by resistance R148, and resistance R153 is connected to amplification
Between the inverting input terminal of device U3 and the output end of amplifier U3, one end of resistance R152 is connected to the anti-phase input of amplifier U3
End, other end ground connection, the output end of amplifier U3 are connected to the normal phase input end of amplifier U4, amplifier U4 by resistance R151
Inverting input terminal be connected with the output end of amplifier U4, the output end of amplifier U4 is connected to the defeated of voltage amplitude adjustment circuit
Enter end.
Shown in referring to figure 5., zero offset circuit includes negative voltage source, slide rheostat RV1, resistance R146, resistance
R147 and capacitor C122, capacitor C123 and amplifier U5, wherein negative voltage source passes sequentially through resistance R146, slide rheostat
It is grounded after RV1 and resistance R147, the sliding end of slide rheostat is connected to the normal phase input end of amplifier U5, and amplifier U5's is anti-
Phase input terminal is connected with its output end, and one end of capacitor C122 and capacitor C123 are respectively connected to the inverting input terminal of amplifier U5
With the output end of amplifier U5, the other end of capacitor C122 and capacitor C123 are grounded, and the output end of amplifier U5 passes through resistance
R148 is connected to the normal phase input end of amplifier U3.The bias voltage of zero offset circuit generation -1.5V, then amplifier U3's
Output end forms a 0.5* (Vdac- 1.5) voltage signal of * (R153/R152+1), wherein:VdacFor the output of D/A conversion module
The value of modulated analog signal, R153/R152 are the ratio between resistance R153 and the resistance value of resistance R152, slide variable resistance by adjusting
The adjustment of amount of bias may be implemented in the resistance value of device RV1.
It please refers to shown in Fig. 6, voltage amplitude adjustment circuit includes digital regulation resistance U6, resistance R162, resistance R163, sliding
Rheostat RV2, electrolytic capacitor C124 and capacitor C126, digital regulation resistance U6 use X9C103S.The high voltage of digital regulation resistance U6
Input terminal (the 3rd pin) is connected to the output end of amplifier U4, the increase input terminal (of digital regulation resistance U6 by resistance R163
2 pins) and lifting input terminal (the 1st pin) be respectively connected to STM32F103VET6 single-chip microcontroller the first output end (the 44th pipe
Foot) and second output terminal (the 45th pin), the ground terminal (the 4th pin) of digital regulation resistance U6, chip select input end (the 7th pin) with
And low-voltage input terminal (the 6th pin) is grounded, the power end (the 8th pin) of digital regulation resistance U6 connects a positive supply, number
The sliding end (the 5th pin) of potentiometer U6 is grounded after passing sequentially through resistance R162 and slide rheostat RV2, electrolytic capacitor C124's
Cathode is connected to the sliding end of slide rheostat RV2, and the anode of electrolytic capacitor C124 is connected to the input terminal of power amplification circuit,
One end of capacitor C126 is grounded, and the other end is connected to the anode of electrolytic capacitor C124.Become by digital regulation resistance U6 and sliding
Resistance device RV2 can be adjusted the voltage amplitude of the output signal of amount of bias adjustment circuit.
It please refers to shown in Fig. 6, power amplification circuit includes amplifier U7, resistance R164, resistance R166, resistance R167, electricity
Solve capacitor C125, electrolytic capacitor C130, the normal phase input end and the one of capacitor C126 of capacitor C127 and capacitor C129, amplifier U7
The anode of end and electrolytic capacitor C124 are all connected with, and the anode of electrolytic capacitor C125 and the anode of electrolytic capacitor C130 are separately connected
To the output end of amplifier U7 and the inverting input terminal of amplifier U7, the cathode of electrolytic capacitor C125 and bearing for electrolytic capacitor C130
Pole is respectively connected to the both ends of the armature winding of isolating transformer;One end is connected to amplification after capacitor C127 and resistance R166 series connection
The output end of device U7, other end ground connection;Both ends after capacitor C129 and resistance R164 series connection are respectively connected to the defeated of amplifier U7
The inverting input terminal of outlet and amplifier U7;One end of resistance R167 is grounded, and the other end is connected to the cathode of electrolytic capacitor C130;
Intermediate-freuqncy signal is exported between the both ends of the secondary windings of isolating transformer, between the both ends of the secondary windings of isolating transformer also
Bridging has capacitor C128 and resistance R165.
Shown in referring to figure 3., the external diaphragm pacemaker of the medium frequency electric stimulation of low frequency modulations further includes a warning circuit, report
Alert circuit includes resistance R103, divider resistance R104, NPN triode Q24, buzzer LS1, zener diode D18 and positive electricity
Source, the both ends of buzzer LS1 are respectively connected to the collector of positive supply and NPN triode Q24, and zener diode D18's is positive and negative
Pole is connected to NPN triode Q24 and positive supply, and the base stage of NPN triode Q24 is connected to processor by resistance R103
Third output end, the emitter ground connection of NPN triode Q24, one end of resistance R104 are connected to the base stage of NPN triode Q24, separately
One end ground connection.
The medium frequency electric of low frequency modulations, amplitude change with the variation of the frequency and amplitude of low frequency signal, have low frequency,
The characteristics of electric current of intermediate frequency and therapeutic effect.The intermediate frequency electro ultrafiltration of low frequency modulations is deeper, is more suitable for the stimulation to nervus phrenicus, especially
The deeper patient of the in vitro table of nervus phrenicus.
Contraction of diaphragm and diastole when respiratory movement, when electrophrenic, cause contraction of diaphragm, so in low frequency modulations
Frequency electricity must use interval modulating wave mode, and in this fashion, amplitude-modulated wave and power-off are alternately present, and amplitude-modulated wave discontinuously occur.
Intermediate-freuqncy signal is as carrier wave, and 1K~100K hertz of frequency range, frequency is higher, and depth of interaction is deeper, in order to appropriate
Stimulation to nervus phrenicus, the frequency of intermediate frequency needs to select by human test.The methods and techniques of human test are not special at this
Illustrate in benefit.
Frequency range to the low-frequency modulation signal of diaphragm nerve stimulation is 10~300 hertz, and the waveform of low frequency includes but not
It is limited to square wave, trapezoidal wave, exponential wave, sine wave, triangular wave etc..
The treatment signal for the external diaphragm pacemaker that we design has the characteristics that:
1, theoretical based on traditional electrotherapy, when being to load to test with pure resistance, intermediate frequency is sine wave, such as Fig. 7
Shown, low-frequency modulation signal can be diversified forms, and including but not limited to positive and negative square wave (such as Fig. 8), positive and negative trapezoidal wave are (as schemed
9), positive and negative sine wave (such as Figure 10), positive and negative triangular wave one (such as Figure 11), positive and negative triangular wave two (such as Figure 12), positive and negative triangular wave three
(such as Figure 13), positive and negative triangular wave four (such as Figure 14), positive and negative triangular wave five (such as Figure 15), positive and negative exponential wave (such as Figure 16).
When low-frequency modulation signal be positive losing side wave, intermediate frequency be sine wave when, external diaphragm pacemaker output treatment signal
As shown in figure 17, wherein T is the period of low-frequency modulation signal, and 1/T is the frequency f of low frequency signal.
2, it is theoretical to expand traditional electrotherapy, when being to load to test with pure resistance, intermediate frequency is positive negative pulse stuffing square wave,
As shown in figure 18, low-frequency modulation signal can be diversified forms, including but not limited to positive and negative square wave (such as Fig. 8), positive and negative trapezoidal wave
(such as Fig. 9), positive and negative sine wave (such as Figure 10), positive and negative triangular wave one (such as Figure 11), positive and negative triangular wave two (such as Figure 12), positive and negative triangle
Wave three (such as Figure 13), positive and negative triangular wave four (such as Figure 14), positive and negative triangular wave five (such as Figure 15), positive and negative exponential wave (such as Figure 16).
3, it is theoretical further to expand electrotherapy, when being to load to test with pure resistance, intermediate frequency is half-sine wave, is such as schemed
Shown in 19, low-frequency modulation signal can be diversified forms, including but not limited to square wave (such as Figure 20), trapezoidal wave (such as Figure 21), just
String wave (such as Figure 22), triangular wave one (such as Figure 23), triangular wave two (such as Figure 24), triangular wave three (such as Figure 25), triangular wave four are (as schemed
26), triangular wave five (such as Figure 27), exponential wave (such as Figure 28).
When low-frequency modulation signal is square wave, intermediate frequency is half-sine wave, the treatment signal of external diaphragm pacemaker output is such as
Shown in Figure 29.
4, it is theoretical further to expand electrotherapy, when being to load to test with pure resistance, intermediate frequency is pulse square wave, such as
Shown in Figure 30, low-frequency modulation signal can be diversified forms, including but not limited to square wave (such as Figure 20), trapezoidal wave (such as Figure 21),
Sine wave (such as Figure 22), triangular wave one (such as Figure 23), triangular wave two (such as Figure 24), triangular wave three (such as Figure 25), triangular wave four are (such as
Figure 26), triangular wave five (such as Figure 27), exponential wave (such as Figure 28).
5, the signal that various intermediate-freuqncy signals is combined into low frequency signal can be alternately present, to reach the mesh for promoting curative effect
's
Such as:Example 1:Intermediate frequency is sine wave, and low-frequency modulation signal is followed successively by positive and negative square wave, positive and negative trapezoidal wave, positive and negative three
The treatment signal of angle wave one, positive and negative exponential wave, external diaphragm pacemaker output is as shown in figure 31.Example 2:Intermediate frequency is pulse side
Wave, low-frequency modulation signal are followed successively by trapezoidal wave, square wave, triangular wave two, sine wave, exponential wave, external diaphragm pacemaker output
It is as shown in figure 32 to treat signal.Example 3:Intermediate frequency is pulse square wave and low-frequency modulation signal is trapezoidal wave, and then intermediate frequency is sine
Wave and low-frequency modulation signal are positive losing side wave, and intermediate frequency is positive negative pulse stuffing square wave and low-frequency modulation signal is positive and negative triangular wave one, in
When frequency is half-sine wave and low-frequency modulation signal is square wave, the treatment signal of external diaphragm pacemaker output is as shown in figure 33.
Above embodiment is only preferred embodiments of the present invention, cannot be protected with this to limit the utility model
Range, the variation of any unsubstantiality that those skilled in the art is done on the basis of the utility model and replacement belong to
In the utility model range claimed.
Claims (10)
1. a kind of external diaphragm pacemaker of the medium frequency electric stimulation of low frequency modulations, it is characterised in that:It include low frequency modulations circuit,
Amount of bias adjustment circuit, voltage amplitude adjustment circuit, power amplification circuit and isolating transformer, the low frequency modulations circuit is to low
Frequency signal is modulated the offset signal that the analog signal to be formed is generated with amount of bias adjustment circuit and is overlapped, superimposed letter
Number successively voltage amplitude is adjusted via voltage amplitude adjustment circuit, power amplification circuit passes through again after carrying out power amplification
Isolating transformer output treatment signal.
2. the external diaphragm pacemaker of the medium frequency electric stimulation of low frequency modulations as described in claim 1, it is characterised in that:It is described low
Frequency modulation circuit is processor, after the processor is modulated low frequency signal, by the D/A modulus of conversion inside the processor
Block exports modulated analog signal.
3. the external diaphragm pacemaker of the medium frequency electric stimulation of low frequency modulations as claimed in claim 2, it is characterised in that:The place
Reason device is STM32F103VET6.
4. the external diaphragm pacemaker of the medium frequency electric stimulation of low frequency modulations as claimed in claim 2, it is characterised in that:It is described inclined
The amount of setting adjustment circuit includes zero offset circuit, resistance R148, resistance R150, resistance R152, resistance R153 and amplifier U3,
The D/A conversion module exports the normal phase input end that modulated analog signal is connected to amplifier U3 by resistance R150, and zero
The output end of point biasing circuit is also connected to the normal phase input end of amplifier U3 by resistance R148, and the resistance R153 is connected to
Between the inverting input terminal of amplifier U3 and the output end of amplifier U3, one end of the resistance R152 is connected to amplifier U3's
Inverting input terminal, other end ground connection, the output end of the amplifier U3 are connected to the input terminal of voltage amplitude adjustment circuit.
5. the external diaphragm pacemaker of the medium frequency electric stimulation of low frequency modulations as claimed in claim 4, it is characterised in that:The zero point
Biasing circuit includes negative voltage source, slide rheostat RV1, resistance R146, resistance R147 and capacitor C122, capacitor C123 and puts
Big device U5, wherein the negative voltage source is grounded after passing sequentially through resistance R146, slide rheostat RV1 and resistance R147, the cunning
Move the normal phase input end that rheostatic sliding end is connected to amplifier U5, the inverting input terminal and its output end of the amplifier U5
Be connected, one end of the capacitor C122 and capacitor C123 be respectively connected to amplifier U5 inverting input terminal and amplifier U5 it is defeated
The other end of outlet, the capacitor C122 and capacitor C123 are grounded, and the output end of the amplifier U5 is connected by resistance R148
It is connected to the normal phase input end of amplifier U3.
6. the external diaphragm pacemaker of the medium frequency electric stimulation of low frequency modulations as described in claim 4 or 5, it is characterised in that:Institute
Stating amount of bias adjustment circuit further includes that first voltage follows circuit and second voltage to follow circuit, wherein the first voltage with
It include amplifier U2 and resistance R149 with circuit, it includes amplifier U4 and resistance R151 that the second voltage, which follows circuit, described
D/A conversion module exports the normal phase input end that modulated analog signal is connected to amplifier U2 by resistance R149, described to put
The output end of big device U2 is connected to the normal phase input end of amplifier U3, the inverting input terminal of the amplifier U2 by resistance R150
It is connected with the output end of amplifier U2, the positive that the output end of the amplifier U3 is connected to amplifier U4 by resistance R151 is defeated
Enter end, the inverting input terminal of the amplifier U4 is connected with the output end of amplifier U4, the output end connection of the amplifier U4
To the input terminal of voltage amplitude adjustment circuit.
7. the external diaphragm pacemaker of the medium frequency electric stimulation of low frequency modulations as claimed in claim 6, it is characterised in that:The electricity
Pressure amplitude adjusting circuit include digital regulation resistance U6, resistance R162, resistance R163, slide rheostat RV2, electrolytic capacitor C124 and
The high voltage input terminal of capacitor C126, the digital regulation resistance U6 are connected to the output end of amplifier U4, institute by resistance R163
The increase input terminal and lifting input terminal for stating digital regulation resistance U6 are respectively connected to the first output end and the second output of processor
End, ground terminal, chip select input end and the low-voltage input terminal of the digital regulation resistance U6 are grounded, the digital regulation resistance U6
Power end connect a positive supply, the sliding end of the digital regulation resistance U6 passes sequentially through resistance R162 and slide rheostat RV2
After be grounded, the cathode of the electrolytic capacitor C124 is connected to the sliding end of slide rheostat RV2, and the electrolytic capacitor C124 is just
Pole is connected to the input terminal of power amplification circuit, one end ground connection of the capacitor C126, and the other end is connected to electrolytic capacitor C124
Anode.
8. the external diaphragm pacemaker of the medium frequency electric stimulation of low frequency modulations as claimed in claim 7, it is characterised in that:The number
Word potentiometer U6 is X9C103S.
9. the external diaphragm pacemaker of the medium frequency electric stimulation of low frequency modulations as claimed in claim 7, it is characterised in that:The function
Rate amplifying circuit includes amplifier U7, resistance R164, resistance R166, resistance R167, electrolytic capacitor C125, electrolytic capacitor C130,
Capacitor C127 and capacitor C129, the normal phase input end of the amplifier U7 and one end of capacitor C126 and electrolytic capacitor C124's
Anode is all connected with, and positive and electrolytic capacitor C130 the anode of the electrolytic capacitor C125 is respectively connected to the output of amplifier U7
The inverting input terminal at end and amplifier U7, the cathode of the electrolytic capacitor C125 and the cathode of electrolytic capacitor C130 are respectively connected to
The both ends of the armature winding of isolating transformer;One end is connected to the defeated of amplifier U7 after the capacitor C127 and resistance R166 series connection
Outlet, other end ground connection;Both ends after the capacitor C129 and resistance R164 series connection are respectively connected to the output end of amplifier U7
With the inverting input terminal of amplifier U7;One end of the resistance R167 is grounded, and the other end is connected to the cathode of electrolytic capacitor C130;
Output treatment signal between the both ends of the secondary windings of the isolating transformer, the two of the secondary windings of the isolating transformer
Also bridging has capacitor C128 and resistance R165 between end.
10. the external diaphragm pacemaker of the medium frequency electric stimulation of low frequency modulations as claimed in claim 2, it is characterised in that:It is described
The external diaphragm pacemaker of the medium frequency electric stimulation of low frequency modulations further includes a warning circuit, and the warning circuit includes resistance
R103, divider resistance R104, NPN triode Q24, buzzer LS1, zener diode D18 and positive supply, the buzzer
The both ends of LS1 are respectively connected to the collector of positive supply and NPN triode Q24, the positive and negative electrode point of the zener diode D18
It is not connected to NPN triode Q24 and positive supply, the base stage of the NPN triode Q24 is connected to processor by resistance R103
Third output end, the emitter ground connection of the NPN triode Q24, one end of the resistance R104 is connected to NPN triode Q24
Base stage, the other end ground connection.
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2020199618A1 (en) * | 2019-03-30 | 2020-10-08 | 合肥智法自然电子科技有限公司 | Multi-electrode acupoint electric-pulse-stimulation tinnitus treatment instrument based on bluetooth communication control, and stimulation scheme therefor |
TWI777339B (en) * | 2020-12-28 | 2022-09-11 | 財團法人工業技術研究院 | Electrical stimulation device and method |
CN116350944A (en) * | 2023-06-01 | 2023-06-30 | 泉州艾奇科技有限公司 | Adjustable constant-power pulse output circuit, system and EMS low-frequency pulse massage instrument |
US12029892B2 (en) | 2019-03-30 | 2024-07-09 | Hefei Ai-Naturalism Electronic Technology Co., Ltd. | Apparatus for treating tinnitus through stimulating multiple acupoints with multi-electrode electric pulse based on bluetooth control and acupoint stimulating method using the same |
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2020199618A1 (en) * | 2019-03-30 | 2020-10-08 | 合肥智法自然电子科技有限公司 | Multi-electrode acupoint electric-pulse-stimulation tinnitus treatment instrument based on bluetooth communication control, and stimulation scheme therefor |
US12029892B2 (en) | 2019-03-30 | 2024-07-09 | Hefei Ai-Naturalism Electronic Technology Co., Ltd. | Apparatus for treating tinnitus through stimulating multiple acupoints with multi-electrode electric pulse based on bluetooth control and acupoint stimulating method using the same |
TWI777339B (en) * | 2020-12-28 | 2022-09-11 | 財團法人工業技術研究院 | Electrical stimulation device and method |
CN116350944A (en) * | 2023-06-01 | 2023-06-30 | 泉州艾奇科技有限公司 | Adjustable constant-power pulse output circuit, system and EMS low-frequency pulse massage instrument |
CN116350944B (en) * | 2023-06-01 | 2023-08-01 | 泉州艾奇科技有限公司 | Adjustable constant-power pulse output circuit, system and EMS low-frequency pulse massage instrument |
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Denomination of utility model: An extracorporeal diaphragmatic pacemaker with low frequency modulation and medium frequency electrical stimulation Effective date of registration: 20211215 Granted publication date: 20181123 Pledgee: Bank of China Limited Guangzhou Pearl River Branch Pledgor: GUANGZHOU ARAHELIO BIOLOGICAL TECHNOLOGY CO.,LTD. Registration number: Y2021980015123 |