CN208125571U - A kind of device of micro-fluidic sorting measurement pellet - Google Patents

A kind of device of micro-fluidic sorting measurement pellet Download PDF

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Publication number
CN208125571U
CN208125571U CN201820684246.9U CN201820684246U CN208125571U CN 208125571 U CN208125571 U CN 208125571U CN 201820684246 U CN201820684246 U CN 201820684246U CN 208125571 U CN208125571 U CN 208125571U
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micro
microchannel
ambulatory
fluidic sorting
plane
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徐鹏
刘宁
李彬
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Jiangsu Security Control Yichuang Information Technology Co ltd
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Nanjing Control Yi Chuang Computer Science And Technology Co Ltd
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Abstract

The utility model discloses a kind of devices of micro-fluidic sorting measurement pellet, which includes jet pump, gas-liquid separation device, micro-fluidic sorting chip, measuring device, filter and liquefier pond;The micro-fluidic sorting chip includes the injection port being sequentially connected to, multistage rectangular-ambulatory-plane microchannel and multiple outlets, and distributing position of the multiple outlet in multistage rectangular-ambulatory-plane microchannel outlet end is corresponding with the pellet of different-grain diameter equilbrium position locating in multistage rectangular-ambulatory-plane microchannel respectively.The utility model is capable of the concentration distribution spectrum of real-time and accurate measurement Inhalable Particulate partial size, and apparatus structure is simple, integration degree is high, at low cost.

Description

A kind of device of micro-fluidic sorting measurement pellet
Technical field
The utility model belongs to air pollutants detection technique field, be related to a kind of pair of pellet carry out sorting and The device of measurement.
Background technique
Environmental protection has become the great subject under discussion that society extremely pays close attention to instantly.In recent years, many areas of China occur again and again Haze weather.Haze mainly by sulfur dioxide, oxynitrides and the pellet in atmosphere caused by, wherein may be inhaled Particulate matter is the main reason to form haze.Pellet, abbreviation PM10 refer to that partial size is less than 10 microns in atmosphere Particulate matter.After pellet is by human body suction body, the positions such as respiratory tract, the alveolar of human body can be deposited on.Particulate matter Partial size it is smaller, then into respiratory tract depth it is deeper.Pellet of the partial size less than or equal to 2.5 microns is known as PM2.5. Compared with PM10, PM2.5 is easier to enter bronchus, alveolar, until the circulatory system of human body.After PM2.5 is precipitated in alveolar It cannot exclude, can cause and aggravate the disease in terms of respiratory system and cardiovascular system.In addition, pellet not only itself It is a kind of pollutant, it can also become the carrier floating of the poisonous and harmful substances such as heavy metal, polycyclic aromatic hydrocarbon in air, to people Health cause to seriously threaten.Thus, become the ring of people's pay attention to day by day to the monitoring and control of Inhalable Particulate Protect project.
Existing pellet measurement method is broadly divided into gravimetric method, β attenuation sensors, light scattering method and oscillation day Flat method.(1) gravimetric method collects particulate matter of the partial size less than 10 microns in air first and excludes the particle that partial size is greater than 10 microns Object.Particulate matter is collected on the filter membrane of preparatory constant weight, according to the variation of filter membrane before and after sampling weight and sampled air volume two A numerical value, which is computed, obtains particle concentration in original air.(2) β ray is a kind of band electrochondria with very strong penetration capacity Son.When it passes through certain thickness absorbed layer, transmitted intensity can gradually weaken with the increase of absorber thickness.(3) light dissipates The basic principle for penetrating method is:Reflected intensity of the illumination on particulate matter is directly proportional to the mass concentration of suspended particulate substance.(4) it vibrates Conical component vibrate microbalance principle is utilized in sedimentation balance method.After being attached with particulate matter on filter membrane, the oscillation frequency of conical component Rate is just affected.Particulate matter quality concentration can be calculated by measuring the variable quantity of frequency of oscillation.
Certain defect is individually present in these four main stream approach at present.Although gravimetric method is classical way, but it was operated Journey heavy workload, filter membrane need to dry weighing and manually change paper, and the degree of automation is low.β attenuation sensors need professional person couple Output signal is parsed.Light scattering method is faint for short grained scattered signal, and measurement stability is not ideal enough.Oscillating balance Measurement error caused by method needs to carry out dust-contained airflow dehumidification treatments, but dehumidification process can be generated due to humidity variation.This Outside, instrument and equipment used in these types of method is all more complicated and expensive.
Utility model content
Technical problem to be solved in the utility model is:Overcome above-mentioned the deficiencies in the prior art, proposes a kind of based on micro- The high throughput of fluidics, high-precision, low cost, automation pellet sort measuring device, can be by can in atmosphere It sucks particulate matter and carries out high-precision sorting by particle size, and the particulate matter after sorting is counted using image analysis software Number, is capable of the concentration distribution spectrum of real-time and accurate measurement Inhalable Particulate partial size, and apparatus structure is simple, integration degree Height, while effectively reducing equipment cost.
The utility model uses following technical scheme to solve above-mentioned technical problem:
A kind of device of micro-fluidic sorting measurement pellet, including jet pump, gas-liquid separation device, micro-fluidic point Chip, measuring device, filter and liquefier pond are selected,
Wherein, the liquid inlet of the jet pump is connected to liquefier pond, the liquid of liquid outlet and gas-liquid separation device Entrance connection,
The liquid outlet of the gas-liquid separation device is connected to the injection port of micro-fluidic sorting chip,
The micro-fluidic sorting chip includes the injection port being sequentially connected to, multistage rectangular-ambulatory-plane microchannel and multiple samples out Mouthful, the multiple outlet multistage rectangular-ambulatory-plane microchannel outlet end distributing position respectively with the inhalable particles of different-grain diameter Object equilbrium position locating in multistage rectangular-ambulatory-plane microchannel is corresponding, and the multiple outlet is connected to measuring device,
The measuring device includes sample cell and measurement module, and sample cell collects the liquid from the outlet, measurement For measuring to the intracorporal pellet of the liquid, the liquid outlet of sample cell is connected to module with filter,
The liquid outlet of the filter is connected to liquefier pond.
Preferably, the multistage rectangular-ambulatory-plane microchannel includes the arc microchannel alternately connected and long straight microchannel.
Preferably, the cross section of the multistage rectangular-ambulatory-plane microchannel is rectangle, ellipse or circle.
Preferably, the sample cell includes multiple independent sectors, the independent sector and the micro-fluidic sorting chip The multiple outlet corresponds.
Preferably, the measurement module includes microlens, camera and embedded analysis module, the microlens with Sample cell optical communication, the camera and microlens are optical coupled, carry out figure to the intracorporal pellet of the liquid As acquisition, and the camera and embedded analysis module are established and are communicated to connect, and camera acquired image information input arrives Embedded analysis module.
Preferably, the multistage rectangular-ambulatory-plane microchannel uses two-stage rectangular-ambulatory-plane structure.
The utility model compared with the prior art by using the above technical solution, has the following technical effects:
The utility model is different from existing pellet and sorts measuring device.The utility model is according to inhalable Grain object particle size sorts pellet, and used principle is that inertia force fluid focus and Dien are vortexed, institute The particulate matter separation unit used is micro-fluidic device.
The utility model has the characteristics that high throughput, high degree of automation, easy to operate, at low cost.
Detailed description of the invention
Fig. 1 is the structural schematic diagram that the micro-fluidic sorting of the utility model measures the device of pellet.
Fig. 2 is micro-fluidic sorting chip structure schematic diagram.
Fig. 3 is seperated schematic diagram of the particle in microchannel exit.
Specific embodiment
The grain sorting principle summary of the utility model is as follows:
In a long straight microchannel, the particulate matter carried by fluid is because of shearing force FSLIt acts on and is transported towards conduit wall direction It is dynamic.At the same time, particulate matter is again by the reaction force F from conduit wallWL.The resultant force of the two power is known as net lift FL.It is right The particle for being a in the diameter being in long straight microchannel, suffered by the relationship of net lift and its diameter be:FL∝a4.Net Under the action of lift, particle can be in the equilbrium position away from the relatively fixed distance of conduit wall, and locating for different size of particle Equilbrium position is different.
When microchannel is arcuate structure, due to the bending of microchannel, in terms of the cross section of microchannel, middle position fluid Transverse flow speed highest, and close to outside microchannel side wall flow velocity it is minimum, to generate pressure and velocity gradient, and then micro- The upper half and lower half of the cross section in channel are respectively formed Dien vortex.Particulate matter in Dien vortex will receive Dien Drag FDEffect.The motion state of particle is by net lifting force FLWith Dien drag FDInteraction determined.Net lifting force FLWith Dien drag FDRatio be represented by
Wherein, a is particulate matter diameter, DhReferred to as hydraulic diameter is determined, i.e. D by the high h and width w of microchannel cross-sectionh= 2wh/(w+h).To focus particulate matter, need to meet Rf> 0.04 or a/Dh>0.07.The particulate matter of different-grain diameter is in arc It can be focused in channel in the distance different relative to conduit wall.
In particulate matter assorting room, the utility model is creatively used to be sorted different from existing pellet The principle of technology.
Below in conjunction with attached drawing and preferred embodiment, to according to specific embodiment provided by the utility model, structure, feature And its effect, detailed description are as follows:
The device of the micro-fluidic sorting measurement pellet of one kind as shown in Figure 1, including jet pump 11, gas-liquid separation Device 12, micro-fluidic sorting chip 13, measuring device 14, filter 15 and liquefier pond 16.Jet pump 11 include ejector and Working barrel.Wherein, liquefier is pumped into ejector using pressure by working barrel, sprays working fluid by the nozzle at high speeds of ejector Out, air to be measured is mixed since negative pressure is inhaled into the intracavitary of ejector with liquefier.Gas-liquid is transported to by mixed sample Separator 12, extra air are separated with liquid in this device, and only remaining fluid sample is transported to next functional unit.? In the microchannel of micro-fluidic sorting chip 13, since the particulate matter of different-grain diameter is in arc microchannel 22 and long straight microchannel 23 Interior suffered inertia force is different with Dien drag, causes them to be eventually focused on the different location of microchannel, finally It is flowed out from different outlets, to reach separating effect.Particulate matter by sorting is collected into measuring device 14, by image Acquisition and analysis, obtain the size and concentration values of particulate matter.In filter 15, the liquid flowed out from measuring device 14 can quilt Further filtering removes impurity.The liquefier being recovered is transported in liquefier pond 16, is realized and is recycled.
As shown in Fig. 2, the micro-fluidic sorting chip 13 include an injection port 21, multistage rectangular-ambulatory-plane microchannel, and Several 1~N of outlet, by arc microchannel 22 and long straight 23 two parts of microchannel, alternately connection is formed for microchannel.Outlet is straight Diameter is unified, and is greater than 20 microns.In a preferred embodiment, microchannel one expands structure and is connected to each outlet, such as Shown in Fig. 2.But the connection structure of microchannel and outlet is without being limited thereto.
The micro-fluidic sorting chip 13 can be prepared on makrolon material by Shooting Technique.
Measuring device 14 includes sample cell and measurement module.Measurement module includes microlens, camera and embedded point Analyse module.Sample cell collects the particulate matter sub-elected by micro-fluidic sorting chip 13.Microlens cooperate camera to sample Particulate matter in pond carries out Image Acquisition.Institute's acquired image information input is to embedded analysis module, by image analysis The processing of program obtains particulate matter information of number.Flow rate of liquid because entering micro-fluidic sorting chip 13 is known quantity, and is counted The bore of a outlet be it is fixed, then the total amount of liquid that each independent sector of sample cell is flowed into certain time is known quantity, Thus the particle in fluid sample can be calculated from the particulate matter number that each outlet flows out by counting in certain time Object concentration.
In the non-limiting illustrated embodiment of the device of micro-fluidic sorting measurement pellet, go out sample using three Mouth design.Respectively as grain diameter less than 2.5 microns, grain diameter is greater than 2.5 microns and less than 10 three outlets The outlet of the particulate matter of micron and grain diameter greater than 10 microns;And this three outlets with 14 phase of rear end measuring device Even.Injection port 21 is located at the central location of rectangular-ambulatory-plane structure, is connected by fluid path with the outlet of gas-liquid separation device 12.Make For preferred embodiment, using two-stage rectangular-ambulatory-plane structure.As a preferred embodiment, microchannel cross-section uses rectangle, more specifically , long side is 400 microns, and short side is 150 microns.The end of micro-fluidic sorting chip 13 forms point being made of three outlets Branch structure.From bottom to top number consecutively be outlet 24, outlet 25 and outlet 26, as shown in Figure 3.These three branched structures It is corresponding in turn to three independent sectors of sample cell in measuring device 14.Applicant is in this functional unit creatively by miniflow The phenomenon that particle is focused and separated under inertia force and the effect of Dien vortex in body is applied to pellet and sorts and measure Field achieves high-throughput, high-precision detection effect.
The lightweight dust of three kinds of different-diameters is sorted and measured as analog sample, is as shown in Figure 3 respectively straight The dust particles 34 that 1 micron of diameter, the dust particles 35 and 12 microns of diameter of dust particles 36 that 3 microns of diameter.Contain these three The air sample of dust particles is collected by jet pump 11, is quickly mixed with swiftly flowing liquefier, and herein, particulate matter is mixed Feed liquor agent.And air is then separated from gas-liquid separation device 12.Liquid mixture continuation containing particulate matter is sprayed at a high speed It injects into micro-fluidic sorting chip 13, as a preferred embodiment, flow velocity can be set as 1700 μ l/min.Liquid mixture is micro-fluidic The rectangular-ambulatory-plane microfluidic channel high speed flowing of chip 13 is sorted, it is former under the collective effect of net lifting force and Dien drag Originally the particulate matter being randomly dispersed in liquid stream is just gradually focused point-blank after flowing through the channel of certain length.Because of difference The amount of force that the particulate matter of size is subject to is different, and the particulate matter of different-grain diameter is caused to form different focusing straight lines.By micro- Conduit wall, the size of particulate matter are sequentially reduced channel inner end conduit wall outward, i.e., the focusing that 12 microns of particulate matter 36 is formed Straight line is near microchannel inner end conduit wall, and the focusing straight line that 1 micron of particulate matter 34 is formed is near microchannel outer end channel Wall, and 3 micron particles objects 35 are close to microchannel middle position.In exit, 1 micron particles object 34 is flowed out from outlet 26, and 3 is micro- Rice grain object 35 is flowed out from outlet 25, and 12 micron particles objects 36 are flowed out from outlet 24.The particulate matter of these three sizes is final Separately flow into three different pieces of the sample cell of particulate matter measuring apparatus 14.Camera acquires in certain period of time in sample cell The image information of the particulate matter of collection, embedded analysis module is using embedded image information analysis program to collected particle Object image information is handled, and concentration information of the variable grain object in suspension can be obtained.
Although embodiment described above only describes specific embodiment of the present utility model example, it should be noted that this reality It is as defined in appended claims with novel protection scope.The embodiments of the present invention application without being limited thereto, and And technology described in the utility model can also be used for other field.

Claims (6)

1. a kind of device of micro-fluidic sorting measurement pellet, it is characterised in that:It is filled including jet pump, gas-liquid separation It sets, micro-fluidic sorting chip, measuring device, filter and liquefier pond,
Wherein, the liquid inlet of the jet pump is connected to liquefier pond, the liquid inlet of liquid outlet and gas-liquid separation device Connection,
The liquid outlet of the gas-liquid separation device is connected to the injection port of micro-fluidic sorting chip,
The micro-fluidic sorting chip includes the injection port being sequentially connected to, multistage rectangular-ambulatory-plane microchannel and multiple outlets, The multiple outlet multistage rectangular-ambulatory-plane microchannel outlet end distributing position respectively with the pellet of different-grain diameter Locating equilbrium position is corresponding in multistage rectangular-ambulatory-plane microchannel, and the multiple outlet is connected to measuring device, the measurement Device includes sample cell and measurement module, and sample cell collects the liquid from the outlet, and measurement module is used for the liquid Intracorporal pellet measures, and the liquid outlet of sample cell is connected to filter,
The liquid outlet of the filter is connected to liquefier pond.
2. the device of micro-fluidic sorting measurement pellet according to claim 1, it is characterised in that:
The multistage rectangular-ambulatory-plane microchannel includes the arc microchannel alternately connected and long straight microchannel.
3. the device of micro-fluidic sorting measurement pellet according to claim 1, it is characterised in that:The multistage The cross section of rectangular-ambulatory-plane microchannel is rectangle, ellipse or circle.
4. the device of micro-fluidic sorting measurement pellet according to claim 1, it is characterised in that:The sample Pond includes multiple independent sectors, the multiple outlet one-to-one correspondence of the independent sector and the micro-fluidic sorting chip.
5. the device of micro-fluidic sorting measurement pellet according to claim 1, it is characterised in that:The measurement Module includes microlens, camera and embedded analysis module, the microlens and sample cell optical communication, the camera shooting Head is optical coupled with microlens, and the camera and embedded analysis module are established and communicated to connect.
6. the device of micro-fluidic sorting measurement pellet according to claim 1, it is characterised in that:The multistage Rectangular-ambulatory-plane microchannel uses two-stage rectangular-ambulatory-plane structure.
CN201820684246.9U 2018-05-09 2018-05-09 A kind of device of micro-fluidic sorting measurement pellet Active CN208125571U (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108318394A (en) * 2018-05-09 2018-07-24 南京安控易创计算机科技有限公司 A kind of micro-fluidic sorting measures the method and device of pellet
CN109946423A (en) * 2019-02-28 2019-06-28 南京普特保仪器有限公司 A kind of micro-fluidic automatic sampling reactor
CN114260036A (en) * 2021-12-23 2022-04-01 西安交通大学 Micro-fluidic chip based on inertial focusing sorting

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108318394A (en) * 2018-05-09 2018-07-24 南京安控易创计算机科技有限公司 A kind of micro-fluidic sorting measures the method and device of pellet
CN108318394B (en) * 2018-05-09 2024-04-16 南京安控易创计算机科技有限公司 Method and device for measuring inhalable particles through microfluidic separation
CN109946423A (en) * 2019-02-28 2019-06-28 南京普特保仪器有限公司 A kind of micro-fluidic automatic sampling reactor
CN114260036A (en) * 2021-12-23 2022-04-01 西安交通大学 Micro-fluidic chip based on inertial focusing sorting
CN114260036B (en) * 2021-12-23 2023-01-31 西安交通大学 Micro-fluidic chip based on inertial focusing sorting

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Effective date of registration: 20221205

Address after: Floor 15, No. 26, Pujiang Road, Gulou District, Nanjing, Jiangsu 210036

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