CN207707921U - A kind of platelet rich plasma enriching apparatus - Google Patents
A kind of platelet rich plasma enriching apparatus Download PDFInfo
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- CN207707921U CN207707921U CN201720389644.3U CN201720389644U CN207707921U CN 207707921 U CN207707921 U CN 207707921U CN 201720389644 U CN201720389644 U CN 201720389644U CN 207707921 U CN207707921 U CN 207707921U
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- hollow tube
- collecting pipe
- rich plasma
- platelet rich
- tube
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Abstract
The utility model discloses a kind of platelet rich plasma enriching apparatus, including heparin tube and collecting pipe, the heparin tube includes outer hollow tube, the open end of the outer hollow tube is connected through a screw thread with collecting pipe, interior hollow tube is also arranged in the outer hollow tube, the interior hollow inside pipe wall is equipped with blood anticoagulant coating；The heparin tube channel of blood flow is equipped with filter membrane, and anticoagulated whole blood is entered by filter membrane in collecting pipe in the interior hollow tube；The rubber plug and Guan Gai for sealing interior hollow tube are additionally provided on the heparin tube.The utility model is small size sampled plasma device, simple in structure, simple operation, be it is a kind of can ensure a small amount of platelet rich plasma that clinical safety uses collect, save set, and realize self timely re-injection conducive to surgery.
Description
Technical field
The utility model is related to a kind of clinical treatment instruments, and in particular to a kind of platelet rich plasma enriching apparatus.
Background technology
Blood of human body includes mainly blood plasma and haemocyte two parts, and the main visible component of haemocyte is red blood cell, leucocyte
And blood platelet.Therefore whole blood can be prepared into various composition, and preserve under ideal conditions, and effective for the treatment of the mankind.
Wherein blood platelet has the function of external hemostasis-coagulation in clinical treatment discovery and quickly starts Endogenous Growth Factors, has to human body
There are good promoting growth of cell and repair.With the development of modern medicine, blood of the micro blood ingredient as being rich in blood platelet
Slurry is widely used in Clinical Surgery and medical cosmetology, from self extraction blood, collects the blood plasma rich in blood platelet, passes through medical treatment in time
Means back into patient skin or tissue surface, reach the treatment of body and restore medical function.It can avoid utilizing ectosome blood
The rejection that product occurs.
At present in-vitro diagnosis both at home and abroad to the acquisition of Platelet-rich plasm and in time injected system, large volume blood at
Separation is prepared mainly using aseptic manipulating system, the operating technology of blood bag system, blood separation device and profession.This technology
It is complicated for operation, it is unfavorable for the purpose of the timely acquisition applications such as medical and beauty treatment, Orthopeadic Surgery, skin surgery；Small size sampled plasma master
It will the cell different to proportion detaches under the action of the centrifugal force using different specific weight inertia separation gel.It is detached in this system
There is separation gel in use into the insecurity for analyzing and being mixed into human body in glue.
Utility model content
Technical problem to be solved in the utility model be existing large volume blood separate and collect device operation it is more multiple
It is miscellaneous, it is unfavorable for the timely acquisition applications such as medical and beauty treatment, Orthopeadic Surgery, skin surgery, and there is safety in small size sampled plasma device
Problem is small size sampled plasma device, and it is an object of the present invention to provide a kind of platelet rich plasma enriching apparatus, simple in structure, operation
It is convenient, be it is a kind of can ensure a small amount of platelet rich plasma that clinical safety uses collect, save set, and realized conducive to surgery
Self timely re-injection.
The utility model is achieved through the following technical solutions：
A kind of platelet rich plasma enriching apparatus, including heparin tube and collecting pipe, the heparin tube include outer hollow tube, institute
The open end and collecting pipe for stating outer hollow tube are connected through a screw thread, and interior hollow tube is also arranged in the outer hollow tube, described interior
Hollow inside pipe wall is equipped with blood anticoagulant coating；The heparin tube channel of blood flow is equipped with filter membrane, anti-freezing in the interior hollow tube
Whole blood is entered by filter membrane in collecting pipe；The rubber plug and Guan Gai for sealing interior hollow tube are additionally provided on the heparin tube.
The outer hollow tube and collecting pipe of the utility model are twisted by screw thread and connect into entire heparin tube external structure, are used
When interior hollow tube is installed in outer hollow tube, by blood anticoagulant even application in assembling on hollow inside pipe wall, lead to
Negative-pressure ward and pressing device are crossed, suction inner air tube is pressed into blood sampling spout at certain negative pressure state, while by pipe lid and rubber plug
It is interior, interior hollow tube or outer hollow tube are usually pressed into ensure negative pressure state in interior hollow tube, pass through the filter membrane mistake of certain pore size
Filter makes to be collected in platelet rich plasma inflow collecting pipe, and finally unscrewing connection screw thread makes collecting pipe be detached from outer hollow tube, then
Platelet rich plasma in collecting pipe can be used to Clinical practice, or can take lower tube cap and rubber plug part immediately, fill in collecting pipe
Mouthful, it keeps in or transports in short-term.Therefore the enriching apparatus of the utility model has the advantages that small, simple in structure, simple operation,
Meanwhile filter membrane and threaded connection are set, so that collecting pipe and separating pipe is separated, detachable connection, can ensure platelet rich plasma
Pure free from admixture, guarantee can clinical safety use, be conducive to preserve, surgery realizes the self operation of re-injection in time.
Preferably, the blood anticoagulant includes that heparin sodium, heparin lithium, sodium citrate and ACD preserve any one of liquid.
Preferably, the ACD preserves all or part of combination formula that liquid includes following component：Glucose, sodium citrate,
Citric acid, adenine, potassium dihydrogen phosphate.
Preferably, the filter membrane is provided close in the interior hollow pipeline of collecting pipe.
The outer hollow tube and collecting pipe of the utility model are twisted by screw thread and connect into entire heparin tube external structure, make to adopt
Blood vessel is set as the two-part structure of detachable connection with collecting pipe, while filter membrane and anticoagulant coating being set in interior hollow tube
Platelet rich plasma modular structure is constituted, operator, which can directly be reached by hollow tube in replacement, replaces filter membrane and anti-freezing
The purpose of blood agent coating.
Preferably, it is additionally provided with network in the heparin tube channel of blood flow, the network is used to support the filter
Film.
The utility model setting network is mainly used for providing a supporting role for filter membrane, ensures the normal use longevity of filter membrane
Life prevents filter membrane from being damaged by blood plasma gravity and influencing collecting effect.Network material can be common plastic material.
Preferably, the outer hollow tube and collecting pipe are all made of PET plastic, modified PET plastics, PETG plastics or PEN modelings
Any material is made in material.
Will outer hollow tube using any material system in PET plastic, modified PET plastics, PETG plastics or PEN plastics
At collecting pipe is made of any material in PET plastic, modified PET plastics, PETG plastics or PEN plastics.With good
Sealing performance and non-absorbency ensure blood anticoagulant stability and suction stability in heparin tube.
Preferably, the interior hollow tube is made of transparent PP plastics or ABS plastic.
The blood status of hollow tube cavity in personal observations easy to operation.
Preferably, the rubber plug is made of medicinal butyl rubber.
By the way that rubber plug is made of medicinal butyl rubber, ensure rubber plug do not adsorb blood anticoagulant and blood constituent and
It is not chemically reacted with blood anticoagulant and blood constituent, while rubber plug being made to keep good close with outer hollow tube and interior hollow tube
Envelope state.
Preferably, the filter membrane is hydrophilic or semi-hydrophilic miillpore filter；The aperture of the miillpore filter is 5~8 μm, institute
State that filter membrane is made of any material in inclined tetrafluoroethene, polyester fiber and polyester plastics or arbitrary two kinds of materials sintering is answered
Condensation material is made.
Red blood cell of the diameter more than 8 μm and leucocyte in anticoagulated blood are trapped on a diameter of 5~8 μm of filter membrane
Layer, i.e., in interior hollow tube, and blood platelet of the diameter less than 5~8 μm is flowed into collecting pipe through membrane filtration and is collected.The filter membrane
Any one material in inclined tetrafluoroethene, polyester fiber and polyester plastics can be used to be made, or using inclined tetrafluoroethene, polyester
The composite material of arbitrary two kinds of materials sintering is made in fiber and polyester plastics.
Preferably, it is fixed with casing on the outer hollow tube open end outer wall, sealing ring is equipped in described sleeve pipe；The set
The outer hollow pipe outer wall that pipe and sealing ring surround is equipped with external screw thread, and the collecting pipe is equipped with interior spiral shell with outer hollow tube connecting pin
Line, collecting pipe and outer hollow tube are by the internal thread and external screw thread adaptation connection, and collecting pipe connects with sealing ring transition cooperation
It connects.
It ensures that collecting pipe and outer hollow tube threaded connection place maintain sealing state by the way that casing and sealing ring is arranged, is conducive to
The blood of preset volume is sucked richness by the negative pressure state of enriching apparatus inner cavity in maintaining to make blood of human body pass through principle of negative pressure
In acquisition means.
The utility model compared with prior art, has the following advantages and advantages：
A kind of platelet rich plasma enriching apparatus of the utility model, the outer hollow tube and collecting pipe of the utility model pass through spiral shell
Line twists and connects into entire heparin tube external structure, by the way that filter membrane is set to interior hollow bottom of the tube, then will be equipped in filter membrane
Blank pipe is installed in outer hollow tube, and blood anticoagulant even application on hollow inside pipe wall, is taken out in assembling by negative pressure
It inhales and pressing device, suction inner air tube passes through one at certain negative pressure state, while by pipe lid and rubber plug indentation blood sampling spout
The membrane filtration of set aperture makes to be collected in platelet rich plasma inflow collecting pipe, and finally unscrewing connection screw thread keeps collecting pipe de-
From outer hollow tube, then the platelet rich plasma in collecting pipe can be used to Clinical practice, or can take lower tube cap plug portion immediately, plug
Enter and collect nozzle, keeps in or transport in short-term.Therefore the enriching apparatus of the utility model has small, simple in structure, operation just
Prompt advantage, meanwhile, filter membrane and threaded connection are set, so that collecting pipe and separating pipe is separated, detachable connection, can ensure rich blood
The pure free from admixture of platelet-poor plasma, guarantee can clinical safety use, be conducive to preserve, surgery realizes the self operation of re-injection in time；
The outer hollow tube and collecting pipe of the utility model are twisted by screw thread and connect into entire heparin tube external structure, make to adopt
Blood vessel is set as the two-part structure of detachable connection with collecting pipe, while filter membrane and anticoagulant coating being set in interior hollow tube
Platelet rich plasma modular structure is constituted, operator, which can directly be reached by hollow tube in replacement, replaces filter membrane and anti-freezing
The purpose of blood agent coating.
Description of the drawings
Attached drawing described herein is used for providing further understanding the utility model embodiment, constitutes the one of the application
Part does not constitute the restriction to the utility model embodiment.In the accompanying drawings：
Fig. 1 is 1 cross section structure schematic diagram of the utility model embodiment；
Fig. 2 is 2 cross section structure schematic diagram of the utility model embodiment；
Fig. 3 is 3 cross section structure schematic diagram of the utility model embodiment.
Label and corresponding parts title in attached drawing：1- collecting pipes, 2- rubber plugs, 3- pipe lids, the outer hollow tubes of 4-, 5- spiral shells
Line, hollow tube in 6-, 7- filter membranes, 8- networks, 9- casings, 10- sealing rings, 11- add hollow tube.
Specific implementation mode
To make the purpose of this utility model, technical solution and advantage be more clearly understood, with reference to embodiment and attached drawing,
The utility model is described in further detail, and the exemplary embodiment and its explanation of the utility model are only used for explaining this
Utility model is not intended to limit the scope of the present invention.
Embodiment 1
As shown in Figure 1, the utility model provides a kind of platelet rich plasma enriching apparatus, including heparin tube and collecting pipe
1, heparin tube is made of outer hollow tube 4 and interior hollow tube 6, and a bite end of outer hollow tube 4 is connect with collecting pipe 1 by screw thread 5, outside
It is arranged with interior hollow tube 6 in hollow tube 4,6 inner wall of interior hollow tube uniformly adheres to blood anticoagulant, close to collecting in outer hollow tube 4
1 end of pipe is equipped with filter membrane 7, and heparin tube anticoagulated whole blood is entered in collecting pipe 1 by filter membrane 7, is equipped in the another port of outer hollow tube 4
Rubber plug 2 and pipe lid 3.
Embodiment 2
As shown in Fig. 2, be further improved on the basis of embodiment 1, the heparin tube is by outer hollow tube 4, additional hollow
Pipe 11, interior hollow tube 6 are constituted, and additional hollow tube 11 is between outer hollow tube 4 and interior hollow tube 6.A bite of outer hollow tube 4
End is connect with collecting pipe 1 by screw thread 5, and 6 inner wall of interior hollow tube uniformly adheres to blood anticoagulant, is added in hollow tube 11 close to receipts
1 end of collector is equipped with filter membrane 7, and heparin tube anticoagulated whole blood is entered in collecting pipe 1 by filter membrane 7, set in the another port of outer hollow tube 4
There are rubber plug 2 and pipe lid 3.
Embodiment 3
As shown in figure 3, being further improved on the basis of embodiment 1, heparin tube is by 6 structure of outer hollow tube 4 and interior hollow tube
At close 1 end of collecting pipe is equipped with filter membrane 7 in interior hollow tube 6, and is embedded in network by ultrasonic welding in interior hollow tube 6
8, network 8 is used to support the filter membrane 7.
Embodiment 4
It is further improved on the basis of embodiment 1,2 or 3, the blood anticoagulant preserves liquid using ACD.The ACD
It includes following component to preserve liquid：Glucose, sodium citrate, citric acid, adenine, potassium dihydrogen phosphate.
Embodiment 5
It is further improved on the basis of embodiment 1,2 or 3, the outer hollow tube 4 uses PET plastic, the collecting pipe 1
It is made of PETG plastic materials；The interior hollow tube 6 is made of transparent PP plastics；The rubber plug 2 uses medicinal butyl rubber
Glue is made；The filter membrane 7 is hydrophilic microporous filter membrane, and the aperture of miillpore filter is 5~8 μm, and filter membrane uses inclined tetrafluoroethene, gathers
Composite filter membrane made of ester fiber and polyester plastics sintering.
Embodiment 6
It is further improved on the basis of embodiment 1,2 or 3, casing is fixed on 4 open end outer wall of the outer hollow tube
9, casing 9 is interior to be equipped with sealing ring 10；4 outer wall of outer hollow tube that casing 9 and sealing ring 10 surround is equipped with external screw thread, collecting pipe 1
Internal thread, collecting pipe 1 and outer hollow tube 4 are equipped with 4 connecting pin of outer hollow tube to connect by the internal thread and external screw thread adaptation,
And collecting pipe 1 is connected with 10 transition of sealing ring.The sealing ring 10 is made of the medical caulking gum of elasticity.
The operation principle for the platelet rich plasma enriching apparatus that embodiment 3 provides：
In use, filter membrane 7 is put on network 8, network 8 is embedded in interior 6 bottom of hollow tube by ultrasonic welding.
Outer hollow tube 4 is screwed up by screw thread 5 with collecting pipe 1 and connects into entire enriching apparatus outer tube structure.It would be embedded with filter membrane 7 and netted branch
The interior hollow tube 6 of frame 8 is assembled in outer hollow tube 4.By auto spraying equipment by blood anticoagulant even application to assembling
6 inner wall of interior hollow tube on.By negative-pressure ward and pressing device, suction inner air tube will be managed at certain negative pressure state
Lid 3 and rubber plug 2 are pressed into heparin tube nozzle, form the rich platelet enriching apparatus having using function.
Specification is acquired according to industry technology Conventional blood, blood lancet device connects blood of human body access and is enriched with rich platelet
Device inner cavity, i.e., in 6 inner cavity of hollow tube, inner cavity principle of negative pressure is hollow including blood by the blood suction apparatus of preset volume
It is mixed with the blood anticoagulant on inner wall in pipe 6, forms anticoagulated whole blood.Upright enriching apparatus, then the diameter in anticoagulated blood is big
It is trapped within a diameter of 5~8 μm of filter membrane, 7 upper layer in 8 μm of red blood cells and leucocyte, i.e., in interior hollow tube.And diameter is less than 5
~8 μm of blood platelet is flowed into through film 7 in collecting pipe 1.Upright 30min, the blood platelet in blood plasma are collected into collecting pipe 1 completely
In, connection screw thread is unscrewed, the platelet rich plasma in collecting pipe 1 can be used to Clinical practice, or can take lower tube cap 3 and glue immediately
Plug portion fills in 1 nozzle of collecting pipe, keeps in or transports in short-term.
Above-described specific implementation mode, to the purpose of this utility model, technical solution and advantageous effect carried out into
One step is described in detail, it should be understood that the foregoing is merely specific embodiment of the present utility model, is not used to limit
Determine the scope of protection of the utility model, within the spirit and principle of the utility model, any modification for being made equally is replaced
It changes, improve, should be included within the scope of protection of this utility model.
Claims (9)
1. a kind of platelet rich plasma enriching apparatus, which is characterized in that including heparin tube and collecting pipe (1), the heparin tube packet
Outer hollow tube (4) is included, the open end of the outer hollow tube (4) is connect with collecting pipe (1) by screw thread (5), the outer hollow tube
(4) interior hollow tube (6) is also arranged in, interior hollow tube (6) inner wall is equipped with blood anticoagulant coating；The heparin tube blood flow
Channel is equipped with filter membrane (7), and the interior anticoagulated whole blood of the interior hollow tube (6) is entered by filter membrane (7) in collecting pipe (1)；It is described to adopt
The rubber plug (2) and pipe lid (3) for sealing interior hollow tube (6) are additionally provided on blood vessel.
2. a kind of platelet rich plasma enriching apparatus according to claim 1, which is characterized in that the blood anticoagulant packet
It includes heparin sodium, heparin lithium, sodium citrate and ACD and preserves any one of liquid.
3. a kind of platelet rich plasma enriching apparatus according to claim 1, which is characterized in that the filter membrane (7) is set to
In interior hollow tube (6) pipeline at collecting pipe (1) end.
4. a kind of platelet rich plasma enriching apparatus according to claim 1, which is characterized in that the heparin tube blood flow is logical
Network (8) is additionally provided in road, the network (8) is used to support the filter membrane (7).
5. a kind of platelet rich plasma enriching apparatus according to claim 1, which is characterized in that the outer hollow tube (4)
Any material in PET plastic, modified PET plastics, PETG plastics or PEN plastics is all made of with collecting pipe (1) to be made.
6. a kind of platelet rich plasma enriching apparatus according to claim 1, which is characterized in that the interior hollow tube (6)
It is made of transparent PP plastics or ABS plastic.
7. a kind of platelet rich plasma enriching apparatus according to claim 1, which is characterized in that the rubber plug (2) uses
Medicinal butyl rubber is made.
8. a kind of platelet rich plasma enriching apparatus according to claim 1, which is characterized in that the filter membrane (7) is parent
Water or semi-hydrophilic miillpore filter；The aperture of the miillpore filter is 5~8 μm.
9. a kind of platelet rich plasma enriching apparatus according to claim 1, which is characterized in that the outer hollow tube (4)
It is fixed with casing (9) on the outer wall of open end, sealing ring (10) is equipped in described sleeve pipe (9)；Described sleeve pipe (9) and sealing ring (10)
Outer hollow tube (4) outer wall surrounded is equipped with external screw thread, and the collecting pipe (1) is equipped with internal thread with outer hollow tube (4) connecting pin,
Collecting pipe (1) and outer hollow tube (4) are connected by the internal thread and external screw thread adaptation, and collecting pipe (1) and sealing ring (10)
Transition is connected.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720389644.3U CN207707921U (en) | 2017-04-14 | 2017-04-14 | A kind of platelet rich plasma enriching apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720389644.3U CN207707921U (en) | 2017-04-14 | 2017-04-14 | A kind of platelet rich plasma enriching apparatus |
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| Publication Number | Publication Date |
|---|---|
| CN207707921U true CN207707921U (en) | 2018-08-10 |
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|---|---|---|---|
| CN201720389644.3U Active CN207707921U (en) | 2017-04-14 | 2017-04-14 | A kind of platelet rich plasma enriching apparatus |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109628286A (en) * | 2019-01-15 | 2019-04-16 | 泰普生物科学（中国）有限公司 | A kind of transport culture apparatus |
| CN110279423A (en) * | 2019-06-28 | 2019-09-27 | 李荣鑫 | A kind of vacuum blood collection tube and its method separating serum |
| CN110721347A (en) * | 2019-10-14 | 2020-01-24 | 西安市红会医院 | Anti-blocking anti-infection shunt pipe and preparation method thereof |
| WO2022077320A1 (en) * | 2020-10-15 | 2022-04-21 | Kartigen Biomedical Inc. | Kit for isolation of platelet-rich plasma and the method using the same |
-
2017
- 2017-04-14 CN CN201720389644.3U patent/CN207707921U/en active Active
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109628286A (en) * | 2019-01-15 | 2019-04-16 | 泰普生物科学（中国）有限公司 | A kind of transport culture apparatus |
| CN109628286B (en) * | 2019-01-15 | 2022-01-07 | 泰普生物科学（中国）有限公司 | Transportation culture apparatus |
| CN110279423A (en) * | 2019-06-28 | 2019-09-27 | 李荣鑫 | A kind of vacuum blood collection tube and its method separating serum |
| CN110279423B (en) * | 2019-06-28 | 2021-10-15 | 李荣鑫 | Vacuum blood collection tube for separating serum and method thereof |
| CN110721347A (en) * | 2019-10-14 | 2020-01-24 | 西安市红会医院 | Anti-blocking anti-infection shunt pipe and preparation method thereof |
| WO2022077320A1 (en) * | 2020-10-15 | 2022-04-21 | Kartigen Biomedical Inc. | Kit for isolation of platelet-rich plasma and the method using the same |
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| GR01 | Patent grant | ||
| CP01 | Change in the name or title of a patent holder |
Address after: 610000, 66, Tian Qin East Street, Chengdu hi tech Zone (West District, Sichuan) Patentee after: Chengdu Ruiqi Medical Technology Co., Ltd Address before: 610000, 66, Tian Qin East Street, Chengdu hi tech Zone (West District, Sichuan) Patentee before: CHENGDU RICH SCIENCE INDUSTRY Co.,Ltd. |
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| CP01 | Change in the name or title of a patent holder |