CN215078995U - Oral cavity cell collection system that drops - Google Patents

Oral cavity cell collection system that drops Download PDF

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Publication number
CN215078995U
CN215078995U CN202121100734.9U CN202121100734U CN215078995U CN 215078995 U CN215078995 U CN 215078995U CN 202121100734 U CN202121100734 U CN 202121100734U CN 215078995 U CN215078995 U CN 215078995U
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collector
oral cavity
sampling
collecting
collecting pipe
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CN202121100734.9U
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曹青霞
梁少明
林梦琴
王子满
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Zhaoqing Medical College
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Zhaoqing Medical College
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Abstract

The utility model relates to a body fluid collection technology field discloses an oral cavity cell collection system that drops. This cell collection system that drops in oral cavity includes sampling ball, collector and collecting pipe, and the collector roughly is lou hopper-shaped and can dismantle the top of connecting in the collecting pipe, has held the sampling liquid in the collecting pipe, and sampling ball and sampling liquid are used for gathering the oral cavity cell that drops of examining the examining person, and the sampling ball can hold in the collector and with the collector between the inner wall form the clearance, and sampling liquid and oral cavity cell that drops can follow in the clearance inflow collecting pipe. This oral cavity cell collection system that drops collects, collects and conserves in an organic whole, is convenient for gather saliva, can gather a large amount of effective oral cavity cells that drop, and the operation degree of difficulty is low, can avoid doctors and patients to contact closely, can reduce operating personnel's burden simultaneously and be gathered personnel's uncomfortable and feel, and can avoid the sample to receive the pollution.

Description

Oral cavity cell collection system that drops
Technical Field
The utility model relates to a body fluid collection technical field especially relates to an oral cavity cell collection system that drops.
Background
With the development of science and technology and the rise of instant detection, the technology of collecting exfoliated oral cells and detecting saliva is developed. Utilize present saliva collection system, the secretion of saliva is very unstable in the collection process, and the collection process is also longer, and when the people under fatigue state, the salivary secretion can reduce, leads to unable qualified saliva of gathering at any time. The conventionally adopted oral exfoliated cell collector needs to be scraped for more than 40 times on the inner wall of the oral cavity, if the force is too small in the scraping process, enough oral exfoliated cells are difficult to collect, and if the force is too large, the oral mucosa is greatly damaged, and even a sampling rod is broken; meanwhile, the human body is easy to feel foreign body sensation and nausea during sampling. In addition, sampling swabs also require a professional technician to operate, require close access by the physician and patient during collection, present a risk of infection, and can result in shortage and overload of medical personnel. The number of effective oral exfoliated cells collected by the samplers is very limited; and some samplers have no related storage devices, so that the problems of autolysis or putrefaction of oral exfoliated cells, even cross infection and the like are easily caused.
SUMMERY OF THE UTILITY MODEL
Based on above, an object of the utility model is to provide an oral cavity cast-off cells collection system collects oral cavity cells and gathers, collects and preserve in an organic whole, and is convenient for gather saliva, can gather a large amount of effectual oral cavity cast-off cells, and the operation degree of difficulty is low, can reduce operating personnel's burden and the uncomfortable of being gathered personnel and feel, and can avoid the sample to receive the pollution.
In order to achieve the purpose, the utility model adopts the following technical proposal:
an oral cavity cast-off cell collecting device comprises a sampling ball, a collector and a collecting pipe;
the collector is approximately funnel-shaped, the collector is detachably connected to the top end of the collecting pipe, and sampling liquid is contained in the collecting pipe;
the sampling ball and the sampling liquid are used for collecting oral exfoliated cells of a person to be detected, the sampling ball can be accommodated in the collector and forms a gap with the inner wall of the collector, and the sampling liquid and the oral exfoliated cells can flow into the collecting pipe along the gap.
As an oral cavity cell collection system's that drops preferred scheme, the inner wall of collector is provided with the bead along the direction from last to bottom, the periphery of sampling ball can the butt in the bead.
As a preferred scheme of the oral cavity cast-off cell collecting device, the protruding edges are provided with a plurality of protruding edges which are uniformly distributed along the circumferential direction of the collector.
As a preferred scheme of the oral exfoliated cell collecting device, the upper port of the collector is elliptical, and two sides of the upper port are concave arc edges.
As a preferred scheme of the oral cavity cast-off cell collecting device, the device further comprises:
the flushing pipe can be detachably connected to the bottom of the collecting pipe, the flushing pipe is filled with preservation liquid, the preservation liquid can be flushed and placed in the collector of the sampling ball, and the preservation liquid can flow into the collecting pipe along the gap after flushing.
As a preferred scheme of the oral cavity cast-off cell collecting device, the sampling ball is made of flocking fibers.
As a preferred scheme of the oral cavity cast-off cell collecting device, the collecting pipe is made of transparent medical plastic materials.
As a preferred scheme of the oral cavity cast-off cell collecting device, the outer wall of the collecting pipe is convexly provided with identification scales.
As a preferred scheme of the oral cavity cast-off cell collecting device, the device further comprises:
and one end of the pull rope is connected with the sampling ball, and the other end of the pull rope freely extends.
As a preferred scheme of the oral cavity cast-off cell collecting device, the device further comprises:
and the collecting pipe cover is hermetically and detachably connected with the pipe opening of the collecting pipe.
The utility model has the advantages that:
the utility model provides an oral cavity cell collection system that drops, including sampling ball, collector and collecting pipe, the collector roughly is hourglass hopper-shaped and can dismantle the top of connecting in the collecting pipe, has held the sampling liquid in the collecting pipe. When the oral cavity cast-off cell of waiting to examine personnel is gathered to needs, put into waiting to examine personnel's oral cavity with sampling ball and sampling liquid together to make sampling ball and sampling liquid roll in the oral cavity, then spit into the collector with sampling ball and sampling liquid together, the sampling ball holds in the collector, and the oral cavity cast-off cell falls into the collecting pipe along with sampling liquid together. The sampling liquid plays a role in lubrication, so that the sampling ball can rotate in the oral cavity more smoothly, and a large amount of effective oral cavity cast-off cells can be collected by the sampling ball and the sampling liquid; the oral exfoliated cell collecting device is low in operation difficulty, and does not need to be operated by professionals, so that the burden of operators and the discomfort of collected personnel are reduced; and the oral exfoliated cells are directly stored in the collecting pipe after being collected, so that the sample can be prevented from being polluted.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings required to be used in the description of the embodiments of the present invention will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the contents of the embodiments of the present invention and the drawings without creative efforts.
Fig. 1 is a schematic structural view of an oral exfoliated cell collecting device provided in an embodiment of the present invention;
fig. 2 is a schematic structural diagram of a sampling ball and a pull rope according to an embodiment of the present invention;
fig. 3 is a schematic structural diagram of a collecting pipe cover provided by an embodiment of the present invention;
fig. 4 is a schematic structural diagram of a collector provided by an embodiment of the present invention;
fig. 5 is a top view of a collector provided by an embodiment of the present invention;
fig. 6 is a diagram illustrating an assembly relationship between a collecting pipe and a flushing pipe according to an embodiment of the present invention.
In the figure:
1-a sampling ball; 2-a collector; 3-a collection tube; 4-convex edges; 5-collecting tube cover; 6-a flushing pipe; 7-pulling a rope; 8-mark scale.
Detailed Description
The present invention will be described in further detail with reference to the accompanying drawings and examples. It is to be understood that the specific embodiments described herein are merely illustrative of the invention and are not limiting of the invention. It should be further noted that, for the convenience of description, only some of the structures related to the present invention are shown in the drawings, not all of the structures.
In the description of the present invention, unless expressly stated or limited otherwise, the terms "connected," "connected," and "fixed" are to be construed broadly, e.g., as meaning permanently connected, detachably connected, or integral to one another; can be mechanically or electrically connected; either directly or indirectly through intervening media, either internally or in any other relationship. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.
In the present disclosure, unless expressly stated or limited otherwise, the first feature "on" or "under" the second feature may comprise direct contact between the first and second features, or may comprise contact between the first and second features not directly. Also, the first feature being "on," "above" and "over" the second feature includes the first feature being directly on and obliquely above the second feature, or merely indicating that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature includes the first feature being directly under and obliquely below the second feature, or simply meaning that the first feature is at a lesser elevation than the second feature.
In the description of the present embodiment, the terms "upper", "lower", "left", "right", and the like are used in the orientation or positional relationship shown in the drawings only for convenience of description and simplicity of operation, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed in a specific orientation, and be operated, and thus should not be construed as limiting the present invention. Furthermore, the terms "first" and "second" are used only for descriptive purposes and are not intended to have a special meaning.
As shown in fig. 1-3, the embodiment provides an oral cavity exfoliated cell collecting device, which includes a sampling ball 1, a collector 2 and a collecting pipe 3, wherein the collector 2 is substantially funnel-shaped, the collector 2 is detachably connected to the top end of the collecting pipe 3, a sampling liquid is contained in the collecting pipe 3, the sampling ball 1 and the sampling liquid are used for collecting exfoliated cells in the oral cavity of a person to be examined, the sampling ball 1 can be contained in the collector 2 and forms a gap with the inner wall of the collector 2, and the sampling liquid and the exfoliated cells in the oral cavity can flow into the collecting pipe 3 along the gap. When needing to gather wait to examine personnel's oral cavity cast-off cell, put into waiting to examine personnel's oral cavity together with sampling liquid sampling ball 1, make sampling ball 1 and sampling liquid roll in the oral cavity through the oral area action, then in telling collector 2 together with sampling ball 1 and sampling liquid, sampling ball 1 holds in collector 2, and the oral cavity cast-off cell falls into collecting pipe 3 along with sampling liquid together. The sampling ball 1 and the sampling liquid can collect a large amount of effective oral exfoliated cells; the sampling liquid plays a role in lubrication, so that the sampling ball 1 can rotate more smoothly in the oral cavity, the sampling liquid assists in collecting the oral cavity cast-off cells, and the problem of difficult salivary secretion or over-high concentration can be solved; the oral exfoliated cell collecting device is low in operation difficulty, and does not need to be operated by professionals, so that the burden of operators and the discomfort of collected personnel are reduced, and short-distance long-time contact between doctors and patients is avoided; and the oral exfoliated cells are directly stored in the collecting pipe 3 after being collected, so that the sample can be prevented from being polluted.
Preferably, the sampling sphere 1 has the shape of an oblate sphere resembling an ellipse. Make sampling ball 1 and wait to examine the personnel oral cavity inner wall and have good contact sense, reduce oral cavity foreign matter and feel, increase sampling ball 1's sampling area simultaneously. In this embodiment, the perimeter of the sampling ball 1 ranges from 4.5cm to 5.5cm, and the long diameter ranges from 1.5cm to 2 cm. Of course, in other embodiments, the size of the sampling sphere 1 may be designed according to the actual situation.
Preferably, the sampling ball 1 is made of flocking fibers, which is beneficial to the collection and elution of cells and can reduce the discomfort of the oral cavity to foreign matters.
Preferably, the volume of the sampling solution ranges from 1.5ml to 2.5 ml. The phenomenon that the sampling ball 1 is lubricated due to too much sampling liquid which causes liquid overflow during sampling or due to too little sampling liquid is avoided.
In order to prevent the sampling ball 1 from being phagocytosed, the oral exfoliated cell collecting device also comprises a pull rope 7, one end of the pull rope 7 is connected with the sampling ball 1, and the other end of the pull rope is freely extended. Preferably, one end of the pull rope 7 extends into the sampling ball 1 and is fixed. In the sampling process, the free end of the pull rope 7 can be pulled to prevent the sampling ball 1 from being phagocytosed.
Further, this oral cavity cell collection system that drops still includes collection tube lid 5, and collection tube lid 5 is sealed and can dismantle the mouth of pipe of connecting in collection pipe 3. Before the sampling, the collecting pipe cover 5 is hermetically connected to the pipe orifice of the collecting pipe 3, so that the sampling liquid in the collecting pipe 3 can be conveniently stored and transported, and can be prevented from being polluted by foreign matters. During sampling, the collecting tube cover 5 is unscrewed, the sampling liquid is sent into the oral cavity of a person to be detected along with the sampling ball 1, and then the collector 2 is connected to the top end of the collecting tube 3 to collect a sample; after sampling is completed, the collector 2 is removed and the collection tube cover 5 is replaced to seal the sample.
As shown in fig. 1 and 4, the lower end of the collector 2 is screwed to the nozzle of the collector tube 3. In this embodiment, the outer peripheral wall of the lower end of the collector 2 is provided with an external thread, and the inner peripheral wall of the pipe orifice of the collecting pipe 3 is provided with an internal thread. Set up the internal thread at 3 mouth of pipe inner walls of collecting pipe, can prevent to collect when dismantling collector 2 after the sample, the sample raffinate leaks outside the 3 mouths of pipe of collecting pipe and causes cross contamination, can avoid foreign object to pollute the 3 mouths of pipe of collecting pipe simultaneously. Illustratively, the outer peripheral wall of the lower end of the collector 2 is provided with two circles of external threads, and the inner peripheral wall of the nozzle of the collecting pipe 3 is provided with three circles of internal threads. Of course, the number of turns of the thread is set according to the actual situation. Preferably, the liquid outlet at the lower end of the collector 2 is in a sharp-nose shape to prevent the liquid drops from hanging.
Preferably, the collector 2 is in a flat funnel shape, the upper port is in an elliptical shape, two sides of the upper port are concave arc edges, and the side wall of the collector 2 is also in an arc shape. That is, the central area of the upper port of the collector 2 is slightly concave, and the two wings are slightly raised to conform to the curve characteristic of the cheek of the human body, so that the collector 2 is attached to the mouth of a person to be detected, and the side leakage is prevented.
Illustratively, the collector 2 has a height of 4cm and a long side length of 4.5cm, and the relatively thin tubular portion of the generally funnel-shaped collector 2 has a length of 1.5cm and a diameter of 1.1 cm. Of course, in other embodiments, the collector 2 may be sized according to the actual circumstances.
In this embodiment the height of the collection tube 3 is 6cm and the volume of the sample and preservative fluids is typically not more than 4ml, but the present embodiment envisages a volume of 5ml for the collection tube 3, taking into account the presence of saliva and air bubbles which may enter the collection tube 3 with the sample and preservative fluids. Of course, in other embodiments, the height and volume of the collector tube 3 may be designed as practical.
Preferably, both the collector tube 2 and the collector tube 3 are made of medical grade polycarbonate.
Furthermore, the collecting pipe 3 is made of transparent medical plastic materials, and the outer wall of the collecting pipe 3 is convexly provided with identification scales 8. Illustratively, the identification scale 8 ranges from 1ml to 5 ml. Set up bellied sign scale 8 at collecting pipe 3 outer wall and can enough conveniently read the sample volume, also played the antiskid effect, prevent that collecting pipe 3 landing and lead to the sample to spill over.
As shown in fig. 1 and 5, the inner wall of the collector 2 is provided with a rib 4 in the direction from top to bottom, and the outer periphery of the sampling ball 1 can abut against the rib 4. When waiting to examine the personnel and spit into collector 2 with sampling ball 1 and sampling liquid together, 1 butt of sampling ball in bead 4, bead 4 can prevent that sampling ball 1 from blockking up the lower liquid mouth of collector 2, and during sampling liquid flowed into collecting pipe 3 along bead 4 simultaneously, bead 4 played the water conservancy diversion effect for sampling liquid can flow down smoothly to collecting pipe 3 in.
Preferably, the protruding ribs 4 are provided in plurality, and the protruding ribs 4 are uniformly distributed along the circumferential direction of the collector 2. In this embodiment, the ribs 4 are provided with four, and the four ribs 4 are uniformly distributed, but in other embodiments, the number of the ribs 4 can be designed according to actual conditions.
As shown in figure 6, the oral exfoliated cell collecting device further comprises a washing pipe 6, the washing pipe 6 is detachably connected to the bottom of the collecting pipe 3, a preserving fluid is contained in the washing pipe 6, the preserving fluid can wash the sampling ball 1 placed in the collector 2, and the washed preserving fluid can flow into the collecting pipe 3 along a gap. The preservation liquid is used for flushing the sampling ball 1 and the collector 2, so that saliva adhered to the inner wall of the sampling ball 1 or the collector 2 is flushed down into the collecting pipe 3 together, the oral exfoliated cells are preserved, meanwhile, the pollution of residual liquid in the collector 2 to the environment is avoided, and the effect of preserving the oral exfoliated cells is also achieved. The flushing pipe 6 is detachably connected to the bottom of the collecting pipe 3, so that materials are saved, and the flushing pipe is easy to integrally store.
Preferably, the mouth of the flushing pipe 6 is made of hard material to be connected with the collecting pipe 3 conveniently, the body of the flushing pipe 6 is made of soft material, and the pressure in the pipe is increased by extruding the body, so that the preserving fluid is extruded out. More preferably, a sealing film is arranged in the flushing pipe 6, and the sealing film is arranged between the pipe body and the pipe orifice and is used for sealing the preserving fluid so as to prevent the preserving fluid from overflowing after the flushing pipe 6 and the collecting pipe 3 are disassembled. When needs use preserving fluid, can stab a weeping mouth on the seal membrane, then 6 pipe shafts of extrusion flushing pipe, preserving fluid falls through the extrusion mode, can avoid operation process preserving fluid to empty and overflow, also can control the quantity, avoids total liquid measure too big, influences the oral cavity cell recovery operation that drops that detects the experiment.
Illustratively, the preservation solution is prepared from 5% -10% of glycerol, 2% -10% of dimethyl sulfoxide and 80% -90% of normal saline.
Preferably, the oral cavity cast-off cell collection device provided by the implementation is a disposable device, so that cross infection is avoided, and the safety is improved. More preferably, the exfoliated oral cell collector is stored in a sealed sterile bag before use.
The following is the use process of the oral cavity cast-off cell collecting device provided by the implementation:
the oral exfoliated cell collecting device is taken out from the sealed sterile bag, and a person to be detected simply gargles with drinking water before collecting a sample, so that influence of massive impurities in the oral cavity on sampling is prevented; the collecting pipe 3 and the flushing pipe 6 are disassembled, the collecting pipe cover 5 is unscrewed, and then the collector 2 is arranged at the top end of the collecting pipe 3; the sampling liquid and the sampling ball 1 are placed into the oral cavity of a person to be detected, the person to be detected makes the sampling ball 1 roll back and forth, left and right through the action of the oral cavity (the mouth washing action can also be performed), the sampling ball 1 and the sampling liquid are spitted into the collector 2 after rolling for a plurality of circles, the sampling ball 1 is clamped in the collector 2, and the sampling liquid and saliva flow into the collecting pipe 3 together; a liquid leakage port is poked on a sealing film in the flushing pipe 6, flushing liquid is squeezed out of the inner walls of the sampling ball 1 and the collector 2, and the residual sampling liquid and saliva are flushed into the collecting pipe 3 by the flushing liquid; and standing for 15s after the washing is finished, then removing the collector 2, discarding the collector 2, the sampling ball 1 and the washing pipe 6, and finally sealing and screwing the collecting pipe cover 5 on the pipe orifice of the collecting pipe 3.
The oral cavity cell collection system that drops that this embodiment provided collects, collects and preserves in an organic whole, can fix the save immediately after the cell that drops in the oral cavity is collected, has ensured the quality of the cell that drops in the oral cavity, has also made things convenient for the transportation, can avoid the cell that drops in the oral cavity autolysis or corrupt, avoids cross contamination, avoids the collector to bring impurity or foreign matter into because of reasons such as unhairing. The oral cavity cast-off cell collecting device is convenient to collect and has no wound to a human body, and the oral cavity is prevented from being damaged by scraping oral mucosa or directly breaking a sampling rod due to excessive force of part of people, so that the pain of a patient and serious complications caused by damage are avoided. This oral cavity cell collection system that drops simple structure, convenient to use through the sampling of sampling ball 1, can acquire oral cavity cell that drops and saliva fast simultaneously, and furthest obtains a large amount of effective oral cavity cell that drops. The oral cavity cast-off cell collecting device does not need professional training, non-medical personnel can also correctly operate sampling, the working pressure of the medical personnel is reduced, meanwhile, the long-time close contact between doctors and patients during sampling is avoided, a large number of personnel are prevented from queuing and gathering in hospitals to wait for the sampling of the medical personnel, and the infection risk of respiratory diseases is reduced. And the oral cavity cast-off cell collecting device is a disposable device, thereby avoiding cross infection and having higher safety.
It should be noted that the foregoing is only a preferred embodiment of the present invention and the technical principles applied. It will be understood by those skilled in the art that the present invention is not limited to the particular embodiments described herein, but is capable of various obvious changes, rearrangements and substitutions as will now become apparent to those skilled in the art without departing from the scope of the invention. Therefore, although the present invention has been described in greater detail with reference to the above embodiments, the present invention is not limited to the above embodiments, and may include other equivalent embodiments without departing from the scope of the present invention.

Claims (10)

1. An oral cavity cast-off cell collecting device is characterized by comprising a sampling ball (1), a collector (2) and a collecting pipe (3);
the collector (2) is approximately funnel-shaped, the collector (2) is detachably connected to the top end of the collecting pipe (3), and sampling liquid is contained in the collecting pipe (3);
sampling ball (1) with sampling liquid is used for gathering wait to examine personnel's oral cavity cast-off cell, sampling ball (1) can hold in collector (2) and with form the clearance between the inner wall of collector (2), sampling liquid with oral cavity cast-off cell can follow the clearance flows in collection pipe (3).
2. The device for collecting exfoliated cells in the oral cavity according to claim 1, wherein the collector (2) has a rib (4) on the inner wall in the direction from top to bottom, and the outer circumference of the sampling ball (1) can abut against the rib (4).
3. The oral exfoliated cell collector of claim 2, wherein the ribs (4) are provided in plurality, and the ribs (4) are uniformly distributed along the circumference of the collector (2).
4. The device for collecting exfoliated oral cells according to claim 1, wherein the upper port of the collector (2) is elliptical, and the two sides of the upper port are concavely curved edges.
5. The device for collecting exfoliated cells in the oral cavity according to claim 1, further comprising:
flushing pipe (6), can dismantle connect in the bottom of collecting pipe (3), it has preserved liquid to hold in flushing pipe (6), it can wash and place in to preserve liquid sample ball (1) in collector (2), after washing preserve liquid can be followed the clearance flows in collecting pipe (3).
6. The device for collecting exfoliated oral cells according to claim 1, wherein the sampling ball (1) is made of flocking fibers.
7. The device for collecting exfoliated oral cells according to claim 1, wherein the collecting tube (3) is made of transparent medical plastic material.
8. The oral exfoliated cell collecting device of claim 7, wherein the outer wall of the collecting pipe (3) is convexly provided with a mark scale (8).
9. The device for collecting exfoliated cells in the oral cavity according to claim 1, further comprising:
and one end of the pull rope (7) is connected to the sampling ball (1), and the other end of the pull rope freely extends.
10. The device for collecting exfoliated cells in the oral cavity according to claim 1, further comprising:
and the collecting pipe cover (5) is hermetically and detachably connected with the pipe opening of the collecting pipe (3).
CN202121100734.9U 2021-05-21 2021-05-21 Oral cavity cell collection system that drops Active CN215078995U (en)

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CN202121100734.9U CN215078995U (en) 2021-05-21 2021-05-21 Oral cavity cell collection system that drops

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Application Number Priority Date Filing Date Title
CN202121100734.9U CN215078995U (en) 2021-05-21 2021-05-21 Oral cavity cell collection system that drops

Publications (1)

Publication Number Publication Date
CN215078995U true CN215078995U (en) 2021-12-10

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