CN217040174U - Saliva collecting device - Google Patents
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- CN217040174U CN217040174U CN202120682500.3U CN202120682500U CN217040174U CN 217040174 U CN217040174 U CN 217040174U CN 202120682500 U CN202120682500 U CN 202120682500U CN 217040174 U CN217040174 U CN 217040174U
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- 210000003296 saliva Anatomy 0.000 title claims abstract description 94
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- 239000011521 glass Substances 0.000 claims abstract description 6
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims abstract 2
- 230000008878 coupling Effects 0.000 claims abstract 2
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- 238000005859 coupling reaction Methods 0.000 claims abstract 2
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- 229920001296 polysiloxane Polymers 0.000 claims description 4
- 239000003146 anticoagulant agent Substances 0.000 claims description 3
- 229940127219 anticoagulant drug Drugs 0.000 claims description 3
- 239000000701 coagulant Substances 0.000 claims description 3
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- 210000003079 salivary gland Anatomy 0.000 description 7
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- 201000010099 disease Diseases 0.000 description 4
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- 208000021386 Sjogren Syndrome Diseases 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
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- 108010065511 Amylases Proteins 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
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- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 235000019418 amylase Nutrition 0.000 description 1
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- 210000003731 gingival crevicular fluid Anatomy 0.000 description 1
- ZMZDMBWJUHKJPS-UHFFFAOYSA-N hydrogen thiocyanate Natural products SC#N ZMZDMBWJUHKJPS-UHFFFAOYSA-N 0.000 description 1
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- Investigating Or Analysing Biological Materials (AREA)
Abstract
Description
技术领域technical field
本实用新型属于医学唾液收集技术领域,具体涉及一种唾液收集装置。The utility model belongs to the technical field of medical saliva collection, in particular to a saliva collection device.
背景技术Background technique
唾液是由唾液腺分泌液、龈沟液和黏膜渗出液等构成的混合性液体,储存了大量的人类口腔微生物和口腔局部组织以及身体其他部位感染微生物和病毒的RNA和DNA等基因信息[2],人的唾液中99%成分是水,有机物主要是唾液淀粉酶、黏多糖、黏蛋白及溶菌酶等,无机物有钠、钾、钙、氯和硫氰离子等。唾液成分的变化与机体病理生理状态密切相关,被视为“人体健康状态的窗口”,分析唾液成分变化可有效反映机体生理和病理状态[3]。唾液的定量分析可有助于“干燥综合征”等外分泌功能障碍疾病的诊断,唾液的定性分析在内分泌疾病等多学科疾病中,通过测定唾液中具体成分的浓度高低有助于疾病的诊疗。Saliva is a mixed fluid composed of salivary gland secretions, gingival crevicular fluid and mucosal exudates, which stores a large number of human oral microorganisms and local oral tissues and other parts of the body. ] , 99% of human saliva is water, the organic substances are mainly salivary amylase, mucopolysaccharide, mucin and lysozyme, etc., and the inorganic substances are sodium, potassium, calcium, chlorine and thiocyanate ions. The change of saliva composition is closely related to the pathophysiological state of the body, and is regarded as the "window of human health state". Analysis of the change of saliva composition can effectively reflect the physiological and pathological state of the body [3] . Quantitative analysis of saliva can be helpful for the diagnosis of exocrine dysfunction diseases such as "Sjögren's syndrome". Qualitative analysis of saliva is helpful for the diagnosis and treatment of diseases in multidisciplinary diseases such as endocrine diseases by measuring the concentration of specific components in saliva.
目前临床最常采用的唾液收集方式主要有三种:EP管自然流取法,口中转动棉柱法、口中咀嚼棉柱法[1],这些方法均有可能给患者带来长时间张口疲倦、棉絮残留口中等各种不适。各类棉柱法收集方式后续需要离心等繁琐操作,令门诊首诊医生无法直接、直观的通过采集量判断患者唾液腺分泌唾液的功能。重要的是,在此类唾液收集过程中,由于是直接由患者口腔流出或吸附至棉签后离心,均有可能因为患者晃动或医护人员采集时抖动等原因使唾液洒落,无法提供精确的唾液定量分析结果,亦有可能导致唾液污染,在进行唾液后续细菌学检测等定性检测时无法提供准确真实的结果。公开号为CN201922196921.0的中国实用新型公开了一种唾液样本收集的新型收集管,该发明创造可有效防止唾液收集过程中的溅洒,但收集管中设计的多个弧面及扩口型唾液收集罩,均会导致唾液残留,对唾液的定量分析仍有一定影响。At present, there are three most commonly used saliva collection methods in clinical practice: EP tube natural flow method, mouth rotating cotton column method, mouth chewing cotton column method [1] , these methods may bring long-term mouth fatigue and cotton wool residue to patients. Various discomforts in the mouth. Various cotton column collection methods require tedious operations such as centrifugation in the follow-up, so that the first clinic doctor cannot directly and intuitively judge the function of the patient's salivary glands to secrete saliva through the collection volume. Importantly, in this type of saliva collection process, since it is directly discharged from the patient's mouth or adsorbed to a cotton swab and then centrifuged, the saliva may be spilled due to the shaking of the patient or the shaking of the medical staff during collection, which cannot provide accurate saliva quantification. The analysis results may also lead to saliva contamination, and accurate and real results cannot be provided when performing qualitative tests such as subsequent bacteriological testing of saliva. The Chinese utility model with publication number CN201922196921.0 discloses a new collection tube for saliva sample collection. The invention and creation can effectively prevent splashing during the saliva collection process, but the collection tube is designed with multiple curved surfaces and flared mouths. The saliva collection hood will lead to residual saliva, which still has a certain impact on the quantitative analysis of saliva.
由于现有唾液收集技术仍存在收集过程的污染可能、唾液的定性及定量分析不够精准、患者不适感及唾液收集装置设计过于复杂等不足,这些不足都将增加患者就诊过程的不适感、影响患者诊治进程及造成医护人员感染等风险,急需一个设计简单、操作简便、可行性强及便于后续检测的唾液收集装置。Due to the existing saliva collection technology, there are still the possibility of contamination during the collection process, the inaccurate qualitative and quantitative analysis of saliva, the discomfort of the patient, and the overly complicated design of the saliva collection device. In the process of diagnosis and treatment and the risks of infection of medical staff, there is an urgent need for a saliva collection device with simple design, simple operation, strong feasibility and convenient follow-up detection.
实用新型内容Utility model content
为实现上述目的,本实用新型根据血液收集原理,设计了一种通过舌下腺直接收集唾液的无创式的唾液收集装置,具体方案如下:In order to achieve the above purpose, according to the principle of blood collection, the present invention designs a non-invasive saliva collection device that directly collects saliva through the sublingual gland. The specific scheme is as follows:
唾液收集装置,包括唾液采集器,所述唾液采集器由相互连通的吸盘、软管和带保护套的尾针组成,所述吸盘连接软管一端,软管另一端连接带硅胶保护套的尾针。A saliva collection device, including a saliva collector, the saliva collector is composed of an interconnected suction cup, a hose and a tail needle with a protective sleeve, the suction cup is connected to one end of the hose, and the other end of the hose is connected to a tail with a silicone protective sleeve Needle.
进一步地,还包括唾液储存器,所述唾液储存器与带保护套的尾针活动连接。Further, a saliva reservoir is also included, and the saliva reservoir is movably connected with the tail needle with the protective cover.
进一步地,所述唾液储存器为标注有刻度的真空负压玻璃管。Further, the saliva reservoir is a vacuum negative pressure glass tube marked with a scale.
进一步地,所述真空负压玻璃管内添加有抗凝剂或促凝剂。Further, an anticoagulant or a coagulant is added in the vacuum negative pressure glass tube.
进一步地,所述吸盘和保护套均由硅胶材质制成。Further, both the suction cup and the protective cover are made of silicone material.
本实用新型的优点Advantages of the utility model
本实用新型的唾液收集装置为经过舌下腺等唾液腺开口处以负压吸盘收集唾液,收集方式简便、安全且无创。该装置避免了唾液经口、唇流出时,唇部表面携带的细菌及因人为因素导致的唾液飞溅,减少了唾液的损耗及对唾液的污染,且免除后期进行离心等操作,极大的将唾液收集至送检的步骤由繁琐变简单直接,避免了唾液经口流出时的不便以及棉花留存在口中的不适等,患者的耐受度较好,亦有利于医生直接根据流率判断患者相关疾病(如:干燥综合征),且该装置的各部分设计相对简单,其中的软管、尾针及唾液采集管均与现临床常用的采血针、采血管无异,采集方式简便,采集装置简单,使得该装置在后期普及使用上也较为简便,是一种以无创的方式达到最小化污染唾液性质的收集方式。The saliva collecting device of the utility model uses a negative pressure suction cup to collect saliva through the opening of salivary glands such as sublingual glands, and the collection method is simple, safe and non-invasive. The device avoids the bacteria carried on the surface of the lips and the splash of saliva caused by human factors when the saliva flows out of the mouth and lips, reduces the loss of saliva and the pollution of saliva, and avoids the operation of centrifugation in the later stage, which greatly reduces the consumption of saliva. The steps from saliva collection to inspection are changed from tedious to simple and direct, which avoids the inconvenience of saliva flowing out of the mouth and the discomfort of cotton remaining in the mouth. The patient's tolerance is better, and it is also helpful for doctors to directly judge the patient's relatedness based on the flow rate. Diseases (such as Sjogren's syndrome), and the design of each part of the device is relatively simple, the hose, tail needle and saliva collection tube are no different from the blood collection needle and blood collection tube commonly used in clinical practice, the collection method is simple, and the collection device The simplicity makes the device more convenient for later popularization and use, and is a non-invasive way to minimize contamination of saliva.
附图说明Description of drawings
图1为本实用新型唾液收集装置的整体结构示意图。FIG. 1 is a schematic diagram of the overall structure of the saliva collection device of the present invention.
图2为图1的唾液收集器结构示意图。FIG. 2 is a schematic structural diagram of the saliva collector of FIG. 1 .
图3为图1的唾液储存器的结构示意图。FIG. 3 is a schematic structural diagram of the saliva reservoir of FIG. 1 .
图中:In the picture:
1、吸盘;2、透明胶管;3、尾针;4、唾液储存器;5保护套。1. Suction cup; 2. Transparent rubber tube; 3. Tail needle; 4. Saliva reservoir; 5. Protective cover.
具体实施方式Detailed ways
下面结合附图和具体实施例对本实用新型作进一步地解释说明,需要注意的是,本具体实施例不限定本实用新型的保护范围。The present utility model will be further explained below with reference to the accompanying drawings and specific embodiments. It should be noted that the specific embodiments do not limit the protection scope of the present utility model.
如图1至图3所示,本具体实施例提供的一种唾液收集装置,包括唾液采集器和唾液储存器4,唾液采集器主要由相互连通的吸盘1、软管2和带保护套5的尾针3组成,吸盘1连接软管2一端,软管2另一端连接带保护套5的尾针3。优选地,唾液储存器4为标注有刻度的真空负压玻璃管,利用负压自动定量地采集唾液,并且方便能够直观的获取所需要的唾液量。真空负压玻璃管根据不同检测指标预先在其内添加抗凝剂或促凝剂。软管2为透明胶管,吸盘1和保护套5均由硅胶材质制成,吸盘1的直径为5mm。吸盘1的作用在于利用唾液储存器4内的负压吸附于患者唾液腺开口(如舌下腺),直接从唾液腺中负压吸取唾液。尾针3用于刺破唾液储存器4的胶塞穿入唾液储存器内。As shown in FIG. 1 to FIG. 3 , a saliva collection device provided by this specific embodiment includes a saliva collector and a
采集唾液前,先清洁好手部卫生,嘱患者张口,将吸盘1置于患者唾液腺开口位置(如舌下腺处),取下保护套5,将尾针3穿过胶塞,使唾液采集器活动连接于唾液储存器4。根据实际情况决定取样量(如计算1min唾液流量则取样1min),取样结束后,拔出尾针3,将保护套5套回到尾针3上,取下患者口中的吸盘1,唾液储存器4内的唾液根据需要储存或送检。Before collecting saliva, clean your hands first, instruct the patient to open his mouth, place the
使用本实施例的唾液收集装置采集唾液的整个过程无创、无异物残留、唾液流出不经唇部,直接进入唾液储存器4内,医生能够及时得到患者唾液腺的分泌情况,能用作临床体征证据,整个过程无二次接触唾液,从根据上保证了唾液性质、成分不受取样过程的影响,能够达到方便、快捷、直观、准确地收集唾液。The whole process of collecting saliva using the saliva collection device of this embodiment is non-invasive, no foreign matter remains, and the saliva flows directly into the
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