CN207613776U - A kind of blood collection tube of separable blood plasma - Google Patents
A kind of blood collection tube of separable blood plasma Download PDFInfo
- Publication number
- CN207613776U CN207613776U CN201720373325.3U CN201720373325U CN207613776U CN 207613776 U CN207613776 U CN 207613776U CN 201720373325 U CN201720373325 U CN 201720373325U CN 207613776 U CN207613776 U CN 207613776U
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- blood
- gum cover
- tube body
- collection tube
- plasma
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Abstract
The utility model provides a kind of blood collection tube being directly separated blood plasma, including collecting tube body, head tube lid, bottom gum cover, cell screen clothes, multilayer filter membrane, holder and unidirectional baffle, head tube lid is equipped at the top of the collection tube body, bottom is equipped with bottom gum cover；Embedded with the rubber sleeve with collection tube body cooperation inside the head tube lid；The structure of bottom gum cover is plug shape, and upper part center is equipped with the semi-circular recesses that can be used as blood sampling mouth；The collection tubular body is by unidirectional barrier partitions at upper and lower two parts space, and lower part is Blood Sampling Room close to the part of bottom gum cover, and top is plasma collection room close to the part of head tube lid；It is equipped with several beades in Blood Sampling Room, holder, multilayer filter membrane and cell screen clothes is equipped with successively on inner wall, close to unidirectional baffle.The utility model utilizes the physical aspect difference of blood constitutent, energy quick separating blood plasma easy, safe, quick.
Description
Technical field
The utility model is related to clinical treatment equipment technology fields, more particularly to a kind of blood being directly separated blood plasma
Collecting pipe.
Background technology
Venous blood sample can be divided into serum, blood plasma and whole blood three classes according to purposes, and application range is quite extensive, such as use
Analyzed in detection biochemical indicator, blood clotting index, hemorheology index, blood routine analysis, trace element and ion component,
Nutritional ingredient detection, detection of drug concentration, genetic test, infectious disease pathogens detection, microorganism detection etc..
In the prior art in the market common vacuum blood collection tube by heparin tube tube body, rubber plug and skull, additive, label etc.
Composition, itself does not have the function of being directly separated blood plasma, if desired separated plasma must come after blood sampling by centrifuge
At.
Blood plasma is prepared using common vacuum blood collection tube through centrifuge to have the following defects：If on the one hand centrifugation item
Part grasp is bad may to form the breakage for causing collection container in haemolysis or centrifugal process, lead to sample leakage or complete
Damage；On the other hand in centrifugal process and separation after, other visible components of blood plasma and blood mix, by
Under the action of centrifugal force or during storage, endoerythrocytic substance can be discharged into blood plasma, be made to final testing result
At influence, not enough securely and reliably.
Utility model content
In view of the foregoing deficiencies of prior art, the purpose of this utility model is to provide one kind being directly separated blood plasma
Blood collection tube, for solve prepare plasma specimen in the prior art when, caused through centrifuge using vacuum blood collection tube
A series of problems.
For it is safer, quickly prepare plasma specimen, the utility model provides the following technical solutions：
A kind of blood collection tube being directly separated blood plasma, including collect tube body 1, head tube lid 2, bottom gum cover 3, cell
Sieve 4, multilayer filter membrane 5, holder 6 and unidirectional baffle 7, it is characterised in that the top for collecting tube body 1 be equipped with head tube lid 2,
Bottom is equipped with bottom gum cover 3；2 inside of the head tube lid is embedded with the rubber sleeve 9 coordinated with collection tube body 1；The bottom gum cover
3 structure is plug shape, and upper part center is equipped with the semi-circular recesses that can be used as blood sampling mouth；The 1 inside quilt of collection tube body
Unidirectional baffle 7 is separated into two parts space up and down, and lower part is Blood Sampling Room close to the part of bottom gum cover, and top is close to head tube lid
Part be plasma collection room；It is equipped with holder 6, multilayer filter membrane 5 and cell successively on the inner wall of Blood Sampling Room, close to unidirectional baffle 7
Sieve 4；The inner wall for collecting tube body 1 is equipped with one layer of anti-coagulants.
Preferably, it is additionally provided with bead 8 in the Blood Sampling Room, the anti-coagulants of one layer of coating is additionally provided on bead.
Preferably, the holder 6 is glass supporter, and 4 aperture of cell screen clothes is 40 μm, and multilayer filter membrane 5 is aperture 0.22-
20 μm of miillpore filter, and the aperture of miillpore filter is tapered by bottom gum cover 3 to 7 direction aperture of unidirectional baffle.
Preferably, the collection tube body 1 is made of one kind in transparent glass, transparent polymer material.
Preferably, the transparent polymer material, selected from high density polyethylene (HDPE), low density polyethylene (LDPE), polypropylene, polyphenyl
Ethylene, makrolon, polyethylene, terephthalate.
Preferably, the cell screen clothes 4 and 5 material therefor of multilayer filter membrane are selected from miillpore filter, and manufacture material includes
Cellulose acetate, nitrocellulose, mixed cellulose ester, nylon 6, nylon66 fiber, Kynoar, polytetrafluoroethylene (PTFE), polyether sulfone,
Polypropylene material.
Preferably, the anti-coagulants includes heparin sodium, heparin lithium, sodium citrate, EDTAP dipotassium ethylene diamine tetraacetate, ethylenediamine
The stabilizer of tetraacethyl tripotassium, disodium ethylene diamine tetraacetate, potassium oxalate, sodium oxalate, hirudin and target detection thing.
As described above, a kind of blood collection tube being directly separated blood plasma provided by the utility model, has beneficial below
Effect：
1, using the physical aspect difference of blood formed element and plasma component, the principle using simple filtration method is quick
Separated plasma has the characteristics that easy, safe, quick.
2, after being not only made for transparent tube body but also the negative pressure of vacuum blood collection tube, material can be effectively ensured in the material used
It is easy to obtain, at low cost, effect is good, economical and practical, securely and reliably.
3, it is directly separated out qualified blood plasma without traditional centrifugal machine, effectively prevents centrifugal action to blood
Starch the destruction of sample.
Description of the drawings
Fig. 1 is shown as a kind of blood collection tube schematic diagram being directly separated blood plasma of the utility model.
Component label instructions 1. collect tube body, 2. head tube lids, 3. bottom gum covers, 4. cell screen clothes, 5. multilayer filter membranes, 6.
Holder, 7. unidirectional baffles, 8. beades, 9. rubber sleeves
Specific implementation mode
Illustrate that the embodiment of the utility model, those skilled in the art can be by these by particular specific embodiment below
Content disclosed by specification understands other advantages and effect of the utility model easily.
It should be clear that structure, ratio, size etc. depicted in this specification institute accompanying drawings, only coordinating specification to be taken off
The content shown is not limited to the enforceable restriction item of the utility model so that those skilled in the art understands and reads
Part, therefore do not have technical essential meaning, the modification of any structure, the change of proportionate relationship or the adjustment of size are not influencing
Under the effect of the utility model can be generated and the purpose that can reach, should all still it fall in the revealed technology of the utility model
In the range of Rong get Neng is covered.
Embodiment 1
Referring to Fig. 1, a kind of blood collection tube being directly separated blood plasma, including collect tube body 1, head tube lid 2, bottom
Gum cover 3, cell screen clothes 4, multilayer filter membrane 5, holder 6 and unidirectional baffle 7, the top for collecting tube body 1 be equipped with head tube lid 2,
Bottom is equipped with bottom gum cover 3；2 inside of the head tube lid is embedded with the rubber sleeve 9 coordinated with collection tube body 1；The bottom gum cover 3
Structure be plug shape, upper part center be equipped with can be used as blood sampling mouth semi-circular recesses；The 1 inside coverlet of collection tube body
It is separated into two parts space up and down to baffle 7, lower part is Blood Sampling Room close to the part of bottom gum cover, and top is close to head tube lid
Part is plasma collection room；It is equipped with holder 6, multilayer filter membrane 5 and cell sieve successively on the inner wall of Blood Sampling Room, close to unidirectional baffle 7
Net 4；The inner wall for collecting tube body 1 is equipped with one layer of anti-coagulants.Bead 8 is additionally provided in the Blood Sampling Room, on bead
It is additionally provided with the anti-coagulants of one layer of coating.The holder 6 is glass supporter, and 4 aperture of cell screen clothes is 40 μm, and multilayer filter membrane 5 is
The miillpore filter in 0.22-20 μm of aperture, and the aperture of miillpore filter is gradually become by bottom gum cover 3 to 7 direction aperture of unidirectional baffle
It is small.The collection tube body 1 is made of one kind in transparent glass, transparent polymer material.The transparent polymer material,
Selected from high density polyethylene (HDPE), low density polyethylene (LDPE), polypropylene, polystyrene, makrolon, polyethylene, terephthalate.Institute
The cell screen clothes 4 and 5 material therefor of multilayer filter membrane stated are selected from miillpore filter, and manufacture material includes cellulose acetate, nitric acid fibre
Tie up element, mixed cellulose ester, nylon 6, nylon66 fiber, Kynoar, polytetrafluoroethylene (PTFE), polyether sulfone, polypropylene material.Described
Anti-coagulants includes heparin sodium, heparin lithium, sodium citrate, EDTAP dipotassium ethylene diamine tetraacetate, ethylenediamine tetra-acetic acid tripotassium, ethylenediamine tetrem
The stabilizer of acid disodium, potassium oxalate, sodium oxalate, hirudin and target detection thing.
To sum up, the utility model provides a kind of blood collection tube being directly separated blood plasma, need not be set by other
Standby to can be obtained by qualified blood plasma, principle is different from the physical aspect of blood formed element using blood plasma, in heparin tube
Inside is equipped with unidirectional baffle, holder, cell screen clothes and multilayer filter membrane, being separated into Blood Sampling Room and plasma collection inside heparin tube
Room, by the rolling for being coated on several beades for being coated with anti-coagulants in the anti-coagulants and Blood Sampling Room on collecting inboard wall of tube body
Action is used, and the blood of inflow Blood Sampling Room is made not solidify；By being built in cell screen clothes and the multilayer filter collected on inboard wall of tube body
The visible component of film blood is left on Blood Sampling Room, and plasma composition can pass through cell screen clothes and multilayer filter membrane flows into blood sampling
The lower part of pipe, i.e. plasma collection room, to make blood plasma and the visible component of blood separate；It can make inflow blood by unidirectional baffle
The blood plasma of slurry collecting chamber is separated, and is no longer back to Blood Sampling Room, and the plasma specimen of prepared plasma collection room is for each
Kind detection.
Blood collection tube body is made of transparent glass or other transparent polymer materials, is round bottom or sharp bottom, flat tubulose
Structure, bottom are cased with flat bottom gum cover with groove, it is ensured that blood collection tube keeps standing.Cell screen clothes and multilayer
Filter sizes are less than blood formed element, can only filter blood plasma, cannot pass through other blood formed elements；The inner wall of inner tube is coated with
Anti-coagulants.
Rubber sleeve 9 in blood collection tube body head tube lid is made of elastic material, and heparin tube tube body can be fully sealed
Open end, ensure vacuum blood collection tube inside can preset certain negative pressure, and within a certain period of time keep pipe in vacuum degree.
The centre of bottom gum cover is provided with circular groove, convenient for pin puncture of taking a blood sample when blood sampling；The outer diameter of rubber sleeve 9 and heparin tube internal diameter of tube body
Matching, it is ensured that vacuum degree in pipe.
The material for manufacturing blood collection tube body includes silicate glass, borate glass, soda-lime glass, polyester plastic cement material
Material, high molecular material, preferred boric acid salt glass, polyethylene terephthalate, poly ethyldiol modified polyethylene terephthalate
Ester, makrolon, poly-naphthalene dicarboxylic acid glycol ester or polyethylene terephthalate and poly-naphthalene dicarboxylic acid glycol ester composite wood
Material.Because after being not only made for transparent tube body but also the negative pressure of vacuum blood collection tube can be effectively ensured in above-mentioned material, material is easy to
It obtains, cost relative moderate.Or it is selected from transparent polymer material, including high density polyethylene (HDPE), low density polyethylene (LDPE), poly- third
Alkene, polystyrene, makrolon, polyethylene terephthalate or other high molecular materials.
The anti-coagulants of inner tube wall spraying includes heparin sodium, heparin lithium, sodium citrate, EDTAP dipotassium ethylene diamine tetraacetate, second two
Amine tetraacethyl tripotassium, disodium ethylene diamine tetraacetate, potassium oxalate, sodium oxalate, hirudin etc., to adapt to different detection project, such as
Blood sugar test can also add the stabilizer of the target detection things such as sodium fluoride, sodium iodoacetate, as long as after will not be to obtaining blood plasma
Continuous Testing index impacts.
The material of manufacture cell screen clothes includes ultra-fine plant fiber, artificial synthetic fiber, polyester sintered product, filter paper, excellent
Select polypropylene synthetic fibers, polyethylene synthetic fibers, polyethylene terephthalate synthetic fibers, carboxymethyl cellulose, crystallite
Cellulose, processed plant fiber, such as degreasing cotton, the preferred micron order product in aperture of superfine fibre, preferably polyethylene pair
Phthalic acid ester synthetic fibers, this fiber will not form haemolysis, will not be in conjunction with the target detection component in blood.
Can be round sheet with additional multi-layer filter membrane, filter membrane below cell screen clothes, outer diameter is equal with internal diameter of tube body,
It is made of micropore inert hydrophobic material, aperture is less than cellular blood constituents, can effectively obstruct the visible component of blood, itself is not
It can be reacted with any ingredient in blood, any component in blood will not be adsorbed.This material includes cellulose acetate, nitre
The materials such as acid cellulose, mixed cellulose ester, nylon 6, nylon66 fiber, Kynoar, polytetrafluoroethylene (PTFE), polyether sulfone, polypropylene
Manufactured miillpore filter.It is preferred that asymmetric PS membrane, the dissymmetrical structure of membrane material can capture the cellular component in blood and not
It cracks, haemolysis will not be formed, critical biomarker will not be adsorbed.
The utility model effectively overcomes the shortcomings that centrifugal action in the prior art destroys blood plasma and has high industrial profit
With value.
The above embodiments are only illustrative of the principle and efficacy of the utility model, new not for this practicality is limited
Type.Any person skilled in the art can all carry out above-described embodiment under the spirit and scope without prejudice to the utility model
Modifications and changes.Therefore, such as those of ordinary skill in the art without departing from the revealed essence of the utility model
All equivalent modifications completed under refreshing and technological thought or change, should be covered by the claim of the utility model.
Claims (3)
1. a kind of blood collection tube of separable blood plasma, including collect tube body (1), head tube lid (2), bottom gum cover (3), cell
Sieve (4), multilayer filter membrane (5), holder (6) and unidirectional baffle (7), it is characterised in that the top for collecting tube body (1) is equipped with
Head tube lid (2), bottom are equipped with bottom gum cover (3)；Embedded with the rubber coordinated with collection tube body (1) inside the head tube lid (2)
Gum cover (9)；The structure of the bottom gum cover (3) is plug shape, and upper part center, which is equipped with, can be used as the semicircle recessed of blood sampling mouth
Slot；The collection tube body (1) is internal to be separated into two parts space up and down by unidirectional baffle (7), and lower part is close to the portion of bottom gum cover
It is divided into Blood Sampling Room, top is plasma collection room close to the part of head tube lid；On the inner wall of Blood Sampling Room, close to unidirectional baffle (7)
It is equipped with holder (6), multilayer filter membrane (5) and cell screen clothes (4) successively；The inner wall for collecting tube body (1) is equipped with one layer of anti-freezing
Agent.
2. a kind of blood collection tube of separable blood plasma according to claim 1, it is characterised in that in the Blood Sampling Room
It is additionally provided with bead (8), the anti-coagulants of one layer of coating is additionally provided on bead.
3. a kind of blood collection tube of separable blood plasma according to claim 1, it is characterised in that the holder (6) is
Glass supporter, cell screen clothes (4) aperture are 40 μm, and multilayer filter membrane (5) is the miillpore filter in 0.22-20 μm of aperture, and micropore is filtered
The aperture of film is tapered by bottom gum cover (3) to unidirectional baffle (7) direction aperture.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720373325.3U CN207613776U (en) | 2017-04-11 | 2017-04-11 | A kind of blood collection tube of separable blood plasma |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720373325.3U CN207613776U (en) | 2017-04-11 | 2017-04-11 | A kind of blood collection tube of separable blood plasma |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN207613776U true CN207613776U (en) | 2018-07-17 |
Family
ID=62817187
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201720373325.3U Expired - Fee Related CN207613776U (en) | 2017-04-11 | 2017-04-11 | A kind of blood collection tube of separable blood plasma |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN207613776U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111398006A (en) * | 2020-04-02 | 2020-07-10 | 苏州德沃生物技术有限公司 | Whole blood sample pretreatment device |
| CN111595631A (en) * | 2020-06-02 | 2020-08-28 | 新乡医学院三全学院 | Inspection sampling device for basic medicine |
-
2017
- 2017-04-11 CN CN201720373325.3U patent/CN207613776U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111398006A (en) * | 2020-04-02 | 2020-07-10 | 苏州德沃生物技术有限公司 | Whole blood sample pretreatment device |
| CN111595631A (en) * | 2020-06-02 | 2020-08-28 | 新乡医学院三全学院 | Inspection sampling device for basic medicine |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20180717 Termination date: 20190411 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |