CN202173399U - Blood collector capable of directly separating plasma - Google Patents
Blood collector capable of directly separating plasma Download PDFInfo
- Publication number
- CN202173399U CN202173399U CN201120285415XU CN201120285415U CN202173399U CN 202173399 U CN202173399 U CN 202173399U CN 201120285415X U CN201120285415X U CN 201120285415XU CN 201120285415 U CN201120285415 U CN 201120285415U CN 202173399 U CN202173399 U CN 202173399U
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- blood
- plasma
- pipe
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- supporter
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Abstract
The utility model discloses a blood collector used for collecting and directly separating blood so as to obtain plasma. The blood collector is composed of three parts: a blood sampling component, a plasma separating component and a blood sample storage container component. Blood is quantificationally absorbed by an absorbing material in the sampling component and then is added to the blood sample storage container filled with liquid anticoagulant, which is further fully mixed. The plasma separating component provided with a filter core is inserted into the blood sample storage container; the top end of the plasma separating component is provided with a hollow elastic piston; a slight-interference closed cavity is formed between the outside of the piston and the inner wall of the blood sample storage container; the filter core is disposed in the hollow piston; the piston can move from top to bottom; when the piston goes through the collected anticoagulated blood sample, the plasma part of the anticoagulated blood can pass the filter core and go to the upper part of the filter core, and the blood visible component which cannot pass the filter core is still in the lower part of the filter core, so as to realize the target of separating plasma without centrifugation.
Description
[technical field]
This utility model relates to the blood collection technical field, particularly relates to a kind of blood collection device that is used to gather and can direct separation obtains blood plasma.
[background technology]
The blood preparation that medical institutions are used for Clinical Laboratory generally obtains through gathering human vein, tremulous pulse or tip (finger finger tip, heel or ear-lobe) blood, and the type of blood preparation is divided into whole blood, serum and blood plasma.Plasma specimen be meant that blood exsomatizes after anticoagulant handle natural sedimentation or centrifugal after the weak yellow liquid that does not contain blood formed element.The purposes of plasma specimen in Clinical Laboratory very extensively can be used for measuring biochemical composition, amynologic index, coagulation function and gene analysis of blood of human body or the like.
Blood formed element accounts for 40～45% of blood total measurement (volume), and remainder is liquid component.Mostly the method for traditional separated plasma is to utilize blood self visible component different with the proportion between the blood plasma, gathers behind the blood through natural sedimentation or the centrifugal blood plasma that obtains.
[summary of the invention]
The purpose of this utility model is exactly the deficiency that will solve prior art, and a kind of blood collection device of novel separated plasma is provided.
But be to realize the blood collection device of a kind of direct separation blood plasma of above-mentioned purpose design, it is characterized in that described blood collection device preserves container assemblies three parts by blood sampling assembly, separating plasma assembly and blood sample and form; Described blood sample is preserved and is inserted blood sampling assembly or separating plasma assembly in the container assemblies;
A. described blood sampling assembly is made up of supporter (1), draw blood piece (2), handle (3); Described supporter (1) is a hollow tubular structure, and supporter (1) one end is that tubule one end is an extra heavy pipe, and draw blood piece (2) is installed on tubule one end of supporter (1); The external diameter of draw blood piece (2) matches with the internal diameter of supporter (1); Handle (3) is installed on extra heavy pipe one end of supporter (1), and handle (3) bottom is provided with push rod, and push rod is suspended in the top of draw blood piece (2);
B. described separating plasma assembly is deposited pipe (4), hollow elasticity piston (5), filter element (6), handle (7), sealing member (8) by blood plasma and is formed; Described blood plasma is deposited the clear tubular parts that pipe (4) is a hollow; The upper end is a peristome, and the lower end is connected with hollow elasticity piston (5), and hollow elasticity piston (5) inside is provided with filter element (6); Handle (7) top one end is provided with the bulging part; The bottom is provided with push rod, and the push rod bottom connects sealing member (8), and sealing member (8) external diameter matches with the endoporus of hollow elasticity piston (5);
C. described blood sample preservation container assemblies is made up of pipe lid (9), preservation pipe (10), anticoagulant (11), and preservation pipe (10) top connection tube lid (9) is provided with anticoagulant (11) in the preservation pipe (10).
Described anticoagulant (11) adopts heparin class anticoagulant, edetate class anticoagulant or sodium citrate, potassium oxalate, hirudin.
Described supporter (1), handle (3) are plastic injection piece.
Described draw blood piece (2) adopts resilient water absorbing material to process.
The inner permeable material that adopts of described filter element (6) is processed, and filter element (6) outside is provided with one deck filter membrane.
Described sealing member (8) is processed by elastomeric material.
During use, after draw blood piece (2) draw blood with blood sampling assembly, blood blood collection assembly blood sampling end is placed the oral area of preserving pipe (10) down, the blood sample of taking is pushed in the anticoagulant of preserving pipe (10), mix gently by fixed handle (3); The oral area of separating plasma assembly piston end being preserved pipe (10) towards the lower edge pushes; Until the bottom, because piston action is risen to the inside that blood plasma is deposited pipe (4) by the blood plasma part of anticoagulant dilution blood sample through crossing filter element; And can not still be left on the bottom that container is preserved pipe (10) through the blood formed element of filter element; Handle (7), sealing member (8) molectron of separating plasma assembly are put into the inside that blood plasma is deposited pipe (4),, by fixed handle (7) sealing member (8) is placed in blood plasma and deposits the endoporus of pipe (4) and block until the pipe end; Shift out handle (7) and discard, will manage lid (9) and cover the diluting plasma sample that can obtain airtight preservation at the oral area of preserving pipe (10).
This utility model utilizes the visible component of blood own different with the physical aspect of blood plasma, and the visible component of removing blood through the filtering method of orientation obtains blood plasma.Its advantage is, can obtain blood plasma fast with natural sedimentation method comparison this utility model, saves time; Do not need special installation with centrifugal separation comparison this utility model, very easy.In addition,, very simply calculate the diluted multiple of blood, thereby realize quantitative collection, the quantitative purpose of dilution, detection by quantitative owing to can preestablish the amount of sucking blood of blood sampling assembly and add the capacity that blood sample is preserved the anti-freezing liquid in the container assemblies.
[description of drawings]
Fig. 1 is the blood sampling assembly of this utility model;
Fig. 2 is the separating plasma assembly of this utility model;
Fig. 3 is that the blood sample of this utility model is preserved container assemblies;
Among the figure 1, supporter 2, draw blood piece 3, handle 4, blood plasma deposit pipe 5, hollow elasticity piston 6, filter element 7, handle 8, sealing member 9, pipe cover 10, preserve manage 11, anticoagulant.
[specific embodiment]
Illustrate the best mode of implementing this patent below, the manufacturing approach of this utility model is that this professional is conspicuous.
Blood sampling assembly: as shown in Figure 1, blood sampling assembly is made up of three parts.Supporter (1) is a hollow tubular structure, is plastic injection piece, and an end is that tubule one end is an extra heavy pipe; Draw blood piece (2) is installed on tubule one end of supporter (1), processes for slightly resilient water absorbing material, and the internal diameter of external diameter and supporter (1) is suitable; Handle (3) is installed on extra heavy pipe one end of supporter (1), is moulding, and top is handle, and the bottom is a push rod, is suspended in the top of draw blood piece (2).The effect of supporter (1) is a supporter, and draw blood piece (2) is used for draw blood, and handle (3) can be released supporter (1) with draw blood piece (2) for handle.Draw blood piece (2) for nontoxic, do not have and to separate out, not have the water absorbing material that comes off and process, its external diameter can be equal to the internal diameter of the thinner end of supporter (1), through adjusting what of its length checking amount of sucking blood.When handle (3) can be released draw blood piece (2) when pressing downwards very easily.
The separating plasma assembly: as shown in Figure 2, the separating plasma assembly is made up of five parts.Wherein blood plasma is deposited pipe (4), hollow elasticity piston (5), filter element (6) and is combined, and handle (7), sealing member (8) are combined.Blood plasma is deposited pipe (4) and is deposited pipe for blood plasma, is the clear tubular parts of a hollow, and the upper end is a peristome, and the lower end links to each other with hollow elasticity piston (5); Hollow elasticity piston (5) is the hollow elastic piston, and an end is wrapped in the lower end that blood plasma is deposited pipe (4), and the outside is the piston dress; Filter element (6) is fixed in the hollow pipe of hollow elasticity piston (5), is the filter element part, and filter element inside is a kind of permeable material; The outside is one deck filter membrane; The aperture of filter membrane is less than 1 μ m, because the platelet diameter of minimum is at 2～4 μ m in the blood formed element, can be filtered film and intercepts; Handle (7) is a handle, and an end bulging partly is a handle, and stem portion is a push rod, and the top of push rod is sealing member (8), is elastomeric material, and the interior bore portion of external diameter and hollow elasticity piston (5) is suitable, can block the endoporus of hollow elasticity piston (5) easily.With handle (7), sealing member (8) assembly when the inside that blood plasma is deposited pipe (4) promotes downwards, sealing member (8) can come off and block the endoporus of hollow elasticity piston (5) very easily.
Blood sample is preserved container assemblies: as shown in Figure 3, blood sample is preserved container assemblies and is made up of three parts.Pipe lid (9) is the pipe lid, preserves pipe (10) for preserving pipe, and anticoagulant (11) is an anticoagulant.Anticoagulant can be mixed with certain density aqueous solution, and the volume of liquid depends on the multiple of needs dilution.The kind of anticoagulant comprises heparin class anticoagulant (like heparin sodium, Lithium acid heparin), edetate class anticoagulant (like ethylenediamine tetraacetic acid,dipotassium salt, ethylenediaminetetraacetic acid tripotassium, disodiumedetate) and sodium citrate, potassium oxalate, hirudin etc.The internal diameter of preserving pipe (10) is slightly less than the piston-like external diameter of hollow elasticity piston (5), and the external diameter of hollow elasticity piston (5) is with respect to the internal diameter of preserving pipe (10), and the interference degree gets final product less than the 0.5mm cooperation greater than 0.1mm closely.
Embodiment 1
Compound concentration is the sodium citrate solution of 32g/L, draws 0.45mL adding blood sample shown in Figure 3 and preserves in the preservation pipe (10) of container assemblies.By making blood sampling assembly shown in Figure 1, wherein the amount of sucking blood with draw blood piece (2) is set at 50 μ L (size through adjustment draw blood piece (2) verifies that its external diameter can be fixed, but length can be adjusted).With blood specimen collection assembly draw blood 50 μ L, be placed in above-mentioned blood sample and preserve in the preservation pipe (10) of container assemblies and press handle shown in Figure 1 (3), can the blood of taking be pushed into blood sample and preserve container and preserve in the pipe (10), mix gently.It is integrative-structure that the blood plasma of separating plasma assembly shown in Figure 2 is deposited pipe (4), hollow elasticity piston (5), filter element (6); Its piston end is pushed above-mentioned blood sample down preserve in the preservation pipe (10) of container assemblies, promote downwards until container bottom, under piston action; The blood plasma of dilution rises to the inside that blood plasma is deposited pipe (4) through filter element; And can not still be left on container bottom through the blood formed element of filter element, handle (7), the sealing member (8) of separating plasma assembly pushed blood plasma deposit in the pipe (4), until the pipe end; By fixed handle (7) sealing member (8) being filled in blood plasma deposits the inner core aperture of pipe (4) and blocks; Draw-out handle (7) discards, and will manage lid (9) and cover the mouth of pipe of preserving pipe (10), promptly obtains the sodium citrate anticoagulate plasma of dilution in 9: 1.
Embodiment 2
Compound concentration is the Lithium acid heparin solution of 50IU/L, draws 0.1mL adding blood sample shown in Figure 3 and preserves in the preservation pipe (10) of container assemblies.By making blood sampling assembly shown in Figure 1, wherein the amount of sucking blood with draw blood piece (2) is set at 20 μ L.With blood specimen collection assembly draw blood 20 μ L, be placed in above-mentioned blood sample and preserve in the preservation pipe (10) of container assemblies and press handle shown in Figure 1 (3), can the blood of taking be pushed into blood sample and preserve container and preserve in the pipe (10), mix gently.It is integrative-structure that the blood plasma of separating plasma assembly shown in Figure 2 is deposited pipe (4), hollow elasticity piston (5), filter element (6); Its piston end is pushed above-mentioned blood sample down preserve in the preservation pipe (10) of container assemblies, promote downwards until container bottom, under piston action; The blood plasma of dilution rises to the inside that blood plasma is deposited pipe (4) through filter element; And can not still be left on container bottom through the blood formed element of filter element, handle (7), the sealing member (8) of separating plasma assembly pushed blood plasma deposit in the pipe (4), until the pipe end; By fixed handle (7) sealing member (8) being filled in blood plasma deposits the inner core aperture of pipe (4) and blocks; Draw-out handle (7) discards, and will manage lid (9) and cover the mouth of pipe of preserving pipe (10), promptly obtains the anticoagulant heparin blood plasma of dilution in 5: 1.
Embodiment 3
Compound concentration is the ethylenediamine tetraacetic acid,dipotassium salt solution of 180g/L, draws 20 μ L adding blood sample shown in Figure 3 and preserves in the preservation pipe (10) of container assemblies.By making blood sampling assembly shown in Figure 1, wherein the amount of sucking blood with draw blood piece (2) is set at 20 μ L.With blood specimen collection assembly draw blood 20 μ L, be placed in above-mentioned blood sample and preserve in the preservation pipe (10) of container assemblies and press handle shown in Figure 1 (3), can the blood of taking be pushed into blood sample and preserve container and preserve in the pipe (10), mix gently.It is integrative-structure that the blood plasma of separating plasma assembly shown in Figure 2 is deposited pipe (4), hollow elasticity piston (5), filter element (6); Its piston end is pushed above-mentioned blood sample down preserve in the preservation pipe (10) of container assemblies, promote downwards until container bottom, under piston action; The blood plasma of dilution rises to the inside that blood plasma is deposited pipe (4) through filter element; And can not still be left on container bottom through the blood formed element of filter element, handle (7), the sealing member (8) of separating plasma assembly pushed blood plasma deposit in the pipe (4), until the pipe end; By fixed handle (7) sealing member (8) being filled in blood plasma deposits the inner core aperture of pipe (4) and blocks; Draw-out handle (7) discards, and will manage lid (9) and cover the mouth of pipe of preserving pipe (10), promptly obtains the ethylenediamine tetraacetic acid,dipotassium salt anticoagulate plasma of dilution in 1: 1.
Claims (6)
1. but the blood collection device of a direct separation blood plasma; It is characterized in that described blood collection device preserves container assemblies three parts by blood sampling assembly, separating plasma assembly and blood sample and forms, described blood sample is preserved insertion blood sampling assembly or separating plasma assembly in the container assemblies;
A. described blood sampling assembly is made up of supporter (1), draw blood piece (2), handle (3); Described supporter (1) is a hollow tubular structure, and supporter (1) one end is that tubule one end is an extra heavy pipe, and draw blood piece (2) is installed on tubule one end of supporter (1); The external diameter of draw blood piece (2) matches with the internal diameter of supporter (1); Handle (3) is installed on extra heavy pipe one end of supporter (1), and handle (3) bottom is provided with push rod, and push rod is suspended in the top of draw blood piece (2);
B. described separating plasma assembly is deposited pipe (4), hollow elasticity piston (5), filter element (6), handle (7), sealing member (8) by blood plasma and is formed; Described blood plasma is deposited the clear tubular parts that pipe (4) is a hollow; The upper end is a peristome, and the lower end is connected with hollow elasticity piston (5), and hollow elasticity piston (5) inside is provided with filter element (6); Handle (7) top one end is provided with the bulging part; The bottom is provided with push rod, and the push rod bottom connects sealing member (8), and sealing member (8) external diameter matches with the endoporus of hollow elasticity piston (5);
C. described blood sample preservation container assemblies is made up of pipe lid (9), preservation pipe (10), anticoagulant (11), and preservation pipe (10) top connection tube lid (9) is provided with anticoagulant (11) in the preservation pipe (10).
2. but the blood collection device of a kind of direct separation blood plasma as claimed in claim 1 is characterized in that described anticoagulant (11) adopts heparin class anticoagulant, edetate class anticoagulant or sodium citrate, potassium oxalate, hirudin.
3. but the blood collection device of a kind of direct separation blood plasma as claimed in claim 1 is characterized in that described supporter (1), handle (3) are plastic injection piece.
4. but the blood collection device of a kind of direct separation blood plasma as claimed in claim 1 is characterized in that described draw blood piece (2) adopts resilient water absorbing material to process.
5. but the blood collection device of a kind of direct separation blood plasma as claimed in claim 1 is characterized in that the inner permeable material that adopts of described filter element (6) processes, and filter element (6) outside is provided with one deck filter membrane.
6. but the blood collection device of a kind of direct separation blood plasma as claimed in claim 1 is characterized in that described sealing member (8) processed by elastomeric material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201120285415XU CN202173399U (en) | 2011-08-08 | 2011-08-08 | Blood collector capable of directly separating plasma |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201120285415XU CN202173399U (en) | 2011-08-08 | 2011-08-08 | Blood collector capable of directly separating plasma |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202173399U true CN202173399U (en) | 2012-03-28 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201120285415XU Withdrawn - After Issue CN202173399U (en) | 2011-08-08 | 2011-08-08 | Blood collector capable of directly separating plasma |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202173399U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102429665A (en) * | 2011-08-08 | 2012-05-02 | 上海科华检验医学产品有限公司 | Direct blood plasma separation supporting blood collecting method |
| CN109475865A (en) * | 2016-06-30 | 2019-03-15 | 萨斯特德特股份两合公司 | For providing the device of the sample carrier for having adsorption capacity with dried amount of liquid, especially blood |
| CN111789601A (en) * | 2019-04-09 | 2020-10-20 | 李泉 | Blood filter and blood filtering apparatus |
-
2011
- 2011-08-08 CN CN201120285415XU patent/CN202173399U/en not_active Withdrawn - After Issue
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102429665A (en) * | 2011-08-08 | 2012-05-02 | 上海科华检验医学产品有限公司 | Direct blood plasma separation supporting blood collecting method |
| CN102429665B (en) * | 2011-08-08 | 2014-06-25 | 上海科华检验医学产品有限公司 | Direct blood plasma separation supporting blood collecting method |
| CN109475865A (en) * | 2016-06-30 | 2019-03-15 | 萨斯特德特股份两合公司 | For providing the device of the sample carrier for having adsorption capacity with dried amount of liquid, especially blood |
| CN109475865B (en) * | 2016-06-30 | 2021-06-29 | 萨斯特德特股份两合公司 | Device for providing a sample carrier with a dried liquid volume, in particular with an adsorption capacity for blood |
| US11439331B2 (en) | 2016-06-30 | 2022-09-13 | Sarstedt Ag & Co. Kg | Device for making available absorbent sample carriers having a quantity of dried liquid, in particular blood |
| CN111789601A (en) * | 2019-04-09 | 2020-10-20 | 李泉 | Blood filter and blood filtering apparatus |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| AV01 | Patent right actively abandoned |
Granted publication date: 20120328 Effective date of abandoning: 20140625 |
|
| RGAV | Abandon patent right to avoid regrant |