CN206699253U - A kind of novel gradient freezing storing box with temperature temperature indicating - Google Patents
A kind of novel gradient freezing storing box with temperature temperature indicating Download PDFInfo
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- CN206699253U CN206699253U CN201720513393.5U CN201720513393U CN206699253U CN 206699253 U CN206699253 U CN 206699253U CN 201720513393 U CN201720513393 U CN 201720513393U CN 206699253 U CN206699253 U CN 206699253U
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Abstract
It the utility model is related to the program mode gradient cooling device of biological specimen, particularly for the novel gradient freezing storing box with temperature temperature indicating of the Cryopreservation preservation of biological specimen, the lid being hinged including box body and with the box body, also include the box groove being detachably placed in box body, the lid is internally provided with the warming color lump for characterizing temperature, being provided with lid can be from the visual windows of the external observation warming color lump, the present apparatus is simple in construction, it is easy to use, and mobility is strong, the cryopreservation tube of different size can be not only placed simultaneously or freezes bag, and the substantially situation of its temperature change can be observed during freezing, biological specimen is transferred in liquid nitrogen container in time and stored, improve gradient cooling box uses turnover rate, simultaneously because appearance design, its volume exclusion utilization rate also greatly improves, reduce cost.
Description
Technical field
The utility model belongs to a kind of program mode gradient cooling device of biological specimen, particularly for the super of biological specimen
The novel gradient freezing storing box with temperature temperature indicating of cryopreservation preservation.
Background technology
In biological medicine industry, the biological products (or product) after preparation, especially cell, it is necessary to save it in-
,, can be by it from -196 DEG C of profound hypothermia rings so as to when needing in the future to keep its bioactivity in 196 DEG C of profound hypothermia environment
Taken out in border, for preparing the cell needed for culture.Therefore the quality of effect is frozen, will directly determine the life of Cell Cryopreservation
Thing activity and biological characteristics.
At present commercially using frozen cell by the way of mainly have two kinds：First, using the gradient equipped with isopropanol
Cooling box, place it in -80 DEG C of low temperature environment, there is the function of preventing temperature from quickly reducing, ladder in itself using isopropanol
Degree is cooled to -80 DEG C, is then then transferred in liquid nitrogen and stores；Second, the cell that needs are frozen using programmed cooling instrument
Gradient cooling is carried out, is then then transferred in liquid nitrogen container and stores.
The problem of isopropanol gradient cooling box of existing market main flow is primarily present has：Isopropanol gradient cooling box is commonly
Cylindrical state, the cryopreservation tube pipe number that its interior spatial design can place are limited；Second, because its outward appearance is cylindrical shape, its
The space occupied is larger, when gradient cooling is completed, can not such as shift liquid nitrogen container the very first time and preserve, it is necessary to by freezing in it
Sample is transferred in new freezing storing box and preserved, and operation is relatively complicated；3rd, there is no any temperature monitoring dress in gradient cooling box
Put, can not accurate judgement its interior temperature whether reach -80 DEG C, can only empirically judge；4th, the sample of its inner chamber design freezes
Pipe tube seat specification is deposited to fix, can not be general, use cost is higher.
And the present invention is redesigned mainly for existing isopropanol gradient cooling box, its main purpose be in order to
Solves the problems, such as aforementioned four existing for existing market main product.
Utility model content
The utility model provides a kind of novel gradient freezing storing box with temperature temperature indicating for deficiency of the prior art.
The utility model is achieved through the following technical solutions the purpose：
A kind of novel gradient freezing storing box with temperature temperature indicating, including box body and the lid be hinged with the box body, in addition to
The detachable box groove being placed in box body, the lid are internally provided with the warming color lump for characterizing temperature, set on lid
Having can be from the visual windows of the external observation warming color lump.
As preferable, some tube seats for housing biological specimen are provided with the box groove.
Wherein, some tube seats are in X rows, Y row spread configurations.
As another preferable, it is provided with the box groove for the accommodating groove for freezing bag.
Further, the edge of the box groove, which projects, is equipped with sealing ring, under the state that is applied in combination, the box groove and box body
Between form closing space for housing isopropanol.
As preferable, the box body and box groove are in the square bodily form.
Relative to prior art, the beneficial effects of the utility model are：
The present apparatus is simple in construction, easy to use, and mobility is strong, can not only place simultaneously different size cryopreservation tube or
Bag is frozen, and the substantially situation of its temperature change can be observed during freezing, biological specimen is transferred to liquid in time
Stored in nitrogen tank, improve gradient cooling box uses turnover rate, simultaneously because appearance design, its volume exclusion utilization rate is also big
It is big to improve, reduce cost.
Brief description of the drawings
Fig. 1 is the structural representation of the novel gradient freezing storing box of the present utility model with temperature temperature indicating.
Embodiment
The utility model is described in detail below in conjunction with drawings and the specific embodiments.
Embodiment 1.
As shown in figure 1, the present embodiment provides a kind of novel gradient freezing storing box with temperature temperature indicating, including box body 1 and with
The be hinged lid 2 of the box body 1, in addition to the box groove 3 being detachably placed in box body 1, the lid 2 are internally provided with for table
The warming color lump 4 of temperature is levied, when the temperature varies, the color of color lump corresponding templates changes, now according to color lump mould
Plate judges the temperature in gradient cooling box.There is a transparent visual window 5 top of lid 2, can be to it directly to the temperature in it
Sense color lump 4 is observed, and when use terminates, after taking out gradient cooling box, warming color lump 4 is with change, its repeatable utilization.
The present apparatus is simple in construction, easy to use, and mobility is strong, and the jelly of different size can be not only placed on box groove 3
Deposit pipe or freeze bag, and the substantially situation of its temperature change can be observed during freezing, in time turn biological specimen
Move in liquid nitrogen container and store, improve gradient cooling box uses turnover rate, simultaneously because appearance design, its volume exclusion uses
Rate also greatly improves, and reduces cost.
As preferable, some tube seats 6 for housing biological specimen are provided with the box groove 3, can be put in tube seat 6
Put the cryopreservation tube for being contained with biological specimen.
Wherein, some tube seats 6 are in X rows, Y row spread configurations, the quantity of tube seat 6 of each row and column can according to it is required voluntarily
Customization change.
As another preferable, it is provided with the box groove 3 for the accommodating groove for freezing bag, Sheng can be placed in groove
Be placed with biological specimen freezes bag.
Further, the edge of the box groove 3, which projects, is equipped with sealing ring, under the state that is applied in combination, the box groove 3 and box
The closing space for housing isopropanol is formed between body 1, when needing to change isopropanol, box groove 3 is taken out and is operated.
As preferable, the box body 1 be in the square bodily form with box groove 3, and its length and width and the general refrigerator in market freeze frame
Match (consistent with freezing storing box), can be put with stacked, makes full use of all spaces frozen in equipment.
Specifically：When needing, by biological specimen, progressively gradient cooling to -80 DEG C, and when being transferred to liquid nitrogen storage, only needs to select
The gradient cooling box of matching box groove 3 is selected, then by cryopreservation tube or bag is frozen and is put into wherein, then gradient cooling box is placed directly on-
Plug-type in 80 DEG C of refrigerators is frozen in carriage, is observed warming color lump 4 by visual windows 5, is up to -80 DEG C in time
Biological specimen is transferred in liquid nitrogen container stores in time, and can greatly accelerate isopropanol gradient cooling box uses turnover rate.
Those of ordinary skills in the art should understand that：The discussion of any of the above embodiment is exemplary only, not
It is intended to imply that the scope of the present disclosure (including claim) is limited to these examples；Under thinking of the present utility model, the above is real
Applying can also be combined between the technical characteristic in example or different embodiments, and exist as described above of the present utility model
Many other changes of different aspect, for simplicity, they are not provided in details.Therefore, it is all in spirit of the present utility model
Within principle, any omission for being made, modification, equivalent substitution, improvement etc., the scope of protection of the utility model should be included in
Within.
Claims (6)
1. a kind of novel gradient freezing storing box with temperature temperature indicating, including box body and the lid be hinged with the box body, its feature exist
In, in addition to the box groove being detachably placed in box body, the lid be internally provided with the warming color lump for characterizing temperature, box
Cover that be provided with can be from the visual windows of the external observation warming color lump.
2. the novel gradient freezing storing box according to claim 1 with temperature temperature indicating, it is characterised in that set on the box groove
It is equipped with some tube seats for housing biological specimen.
3. the novel gradient freezing storing box according to claim 2 with temperature temperature indicating, it is characterised in that some tube seats
Arranged in X, Y row spread configurations.
4. the novel gradient freezing storing box according to claim 1 with temperature temperature indicating, it is characterised in that set on the box groove
It is equipped with for the accommodating groove for freezing bag.
5. the novel gradient freezing storing box according to claim 1 with temperature temperature indicating, it is characterised in that the side of the box groove
Edge, which projects, is equipped with sealing ring, and under the state that is applied in combination, the closing for housing isopropanol is formed between the box groove and box body
Space.
6. the novel gradient freezing storing box with temperature temperature indicating according to claim 1-5 any one, it is characterised in that institute
It is in the square bodily form that box body, which is stated, with box groove.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720513393.5U CN206699253U (en) | 2017-05-09 | 2017-05-09 | A kind of novel gradient freezing storing box with temperature temperature indicating |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720513393.5U CN206699253U (en) | 2017-05-09 | 2017-05-09 | A kind of novel gradient freezing storing box with temperature temperature indicating |
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| Publication Number | Publication Date |
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| CN206699253U true CN206699253U (en) | 2017-12-05 |
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| CN201720513393.5U Active CN206699253U (en) | 2017-05-09 | 2017-05-09 | A kind of novel gradient freezing storing box with temperature temperature indicating |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109335325A (en) * | 2018-10-09 | 2019-02-15 | 上海原能细胞生物低温设备有限公司 | A kind of biological sample subregion cooling storage device and its operating method |
-
2017
- 2017-05-09 CN CN201720513393.5U patent/CN206699253U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109335325A (en) * | 2018-10-09 | 2019-02-15 | 上海原能细胞生物低温设备有限公司 | A kind of biological sample subregion cooling storage device and its operating method |
| CN109335325B (en) * | 2018-10-09 | 2023-06-27 | 上海原能细胞生物低温设备有限公司 | Biological sample partition cooling storage device and operation method thereof |
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