CN206613034U - It is a kind of to be used for cup-shape electrode of the minitype animal experiment through cranium galvanic current stimulation - Google Patents
It is a kind of to be used for cup-shape electrode of the minitype animal experiment through cranium galvanic current stimulation Download PDFInfo
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- CN206613034U CN206613034U CN201621336247.1U CN201621336247U CN206613034U CN 206613034 U CN206613034 U CN 206613034U CN 201621336247 U CN201621336247 U CN 201621336247U CN 206613034 U CN206613034 U CN 206613034U
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- sleeve
- electrode
- cotton core
- physiological saline
- fixed
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Abstract
The utility model is related to a kind of for cup-shape electrode of the minitype animal experiment through cranium galvanic current stimulation, including sleeve, cotton core and the physiological saline cavity for being installed on sleeve inner;One end of cotton core connects with the one end for the physiological saline cavity being fixed in sleeve, and the other end of cotton core is extended outside sleeve tapering point;The cylindrical end afterbody of sleeve is fixed with the closing cover for sealing physiological saline cavity;The circuit switch head run through is fixed with closing cover, and one end of circuit switch head is fixed in physiological saline cavity.The present apparatus substitutes the rigid head end of traditional metal electrodes by using the cotton core head end of plasticity, with the impedance increase for avoiding electrode and skull loose contact or imprecision of fitting from causing, it is prevented effectively from the long interference to experimental animal normal life of electrode and adds the stability and fastness of electrode fixation, is that electrode is fixed on experimental animal skull surface and creates more easily condition by bone cement for a long time.
Description
Technical field
The utility model belongs to medical experiment apparatus field, and in particular to one kind is used for minitype animal experiment through cranium direct current
The cup-shape electrode of stimulation.
Background technology
Gradually it is proved with the validity and security of physical factor treatment central nervous system disease, on this aspect
The breadth and depth of research constantly extends, wherein, economic portable, operation letter extensive with its indication through cranium galvanic current stimulation
The advantage such as single turns into the focus and focus of the area research, but in the experimental study stage, lacks and be applied to experimental animal, especially
It is the long-term electrode through cranium galvanic current stimulation of the minitype animal experiments such as rodent, seriously constrains the research and development in the field.
In conventional rodent experimental study, each laboratory uses homemade stimulating electrode mostly, and specification, material differ greatly,
Wherein stimulating electrode contact area is with 3.5mm2In the majority, electrode material is generally metal with good conductivity (such as copper, silver), is passed through
Electrode is fixed on skull surface simulation clinic through cranium galvanic current stimulation scene by dentistry bone cement, but finds this in practical application
There are shortcomings in metalloid electrode:1st, due to the out-of-flatness of experimental animal skull surface and the rigidity characteris of metal electrode, electrode
Good contact is unable to skull and often results in impedance increase, and electric conductivity declines, while being brought not to set electrode stimulating area
Certainty;2nd, often hardness is relatively low for the preferable metal of electric conductivity, and deformation is serious when reusing electrode, and exists after anodizing
The shortcoming that electric conductivity declines, greatly reduces the repeat usage of metal electrode, adds experimental cost.
Utility model content
The purpose of this utility model is to overcome shortcoming present in above-mentioned prior art to be used for small test there is provided one kind
Cup-shape electrode of the animal through cranium galvanic current stimulation, has the advantages that to stimulate that stability is good, cost is low.
To achieve the above object, the utility model uses following technical scheme:Including sleeve, cotton core and it is installed in sleeve
The physiological saline cavity in portion;One end of sleeve is in cylinder, and the other end is tapered, and tapered tip opens up hole;Cotton core
One end connects with the one end for the physiological saline cavity being fixed in sleeve, and the other end of cotton core extends sleeve tapering point through hole
It is outside;The cylindrical end afterbody of sleeve is fixed with the closing cover for sealing physiological saline cavity;It is fixed with and is passed through on closing cover
The circuit switch head worn, and one end of circuit switch head is fixed in physiological saline cavity.
The diameter of described cotton core and the internal diameter in the tapered stomidium hole of sleeve are equal in magnitude.
The length of described sleeve is 18-20mm.
The length that described cotton core extends sleeve is 0.9-1.1mm.
The area of described cotton core circular cross section is 2.9-3.5mm2。
It is connected through a screw thread between described sleeve and closing cover.
The utility model has following beneficial effect:Compare prior art, the utility model include sleeve, cotton core and
It is installed on the physiological saline cavity of sleeve inner;One end of sleeve is in cylinder, and the other end is tapered, and tapered tip is offered
Hole;One end of cotton core connects with the one end for the physiological saline cavity being fixed in sleeve, and the other end of cotton core extends through hole
Outside sleeve tapering point;The cylindrical end afterbody of sleeve is fixed with the closing cover for sealing physiological saline cavity;On closing cover
The circuit switch head run through is fixed with, and one end of circuit switch head is fixed in physiological saline cavity.The present apparatus passes through
The rigid head end of traditional metal electrodes is substituted using the cotton core head end of plasticity, to avoid electrode and skull loose contact or fit
Impedance that imprecision is caused increase, adds physiological saline in physiological saline cavity when using, cup-shape electrode using physiological saline as
Conducting medium, electric conductivity is well and stably, it is to avoid the conduction that metal electrode oxidation is caused is sexually revised, and then ensures long-term thorn
The stability of direct current during swashing, can effectively exclude the interference of weak current change or current noise to experimental study, improve
The accuracy of direct current research;The cotton core head end limited size of present apparatus electrode is in sleeve tapering point, and cotton core is diametrically stable, so
Electrode contact area is stably and controllable;" recessed " the shape end of device electrode is smaller compared with " convex " the shape end of traditional metal electrodes simultaneously
Ingeniously, electrode total length is greatly shortened, the long interference to experimental animal normal life of electrode can be prevented effectively from and electricity is added
Extremely fixed stability and fastness, is that electrode is fixed on experimental animal skull surface and created and more facilitates by bone cement for a long time
Condition, disclosure satisfy that minitype animal experiment it is long-term through cranium galvanic current stimulation the need for;In addition, the sleeve of the present apparatus is plastic sheath
Cylinder, material source is extensively, with low cost and easily prepared, and can reuse, and the metal electrode than high cost is more human-oriented
It is practical.The present apparatus is applied to be widely applied and extensive use.
Further, because sleeve leads to be threadedly coupled with closing cover, so as to improve the sealing of device, it is to avoid make
The outflow of used time physiological saline.
Brief description of the drawings
Fig. 1 is present apparatus structural representation;
Fig. 2 is present apparatus sectional view;
In figure:1:Sleeve;2:Cotton core;3:Physiological saline cavity;4:Circuit switch head;5:Closing cover.
Embodiment
Below in conjunction with the accompanying drawings, the utility model is described in further detail.
Referring to Fig. 1, the utility model includes sleeve 1, cotton core 2 and the physiological saline cavity 3 being installed on inside sleeve 1;Set
One end of cylinder 1 is in cylinder, and the other end is tapered, and tapered tip opens up hole;One end of cotton core 2 is with being fixed on sleeve 1
One end of interior physiological saline cavity 3 connects, and the other end of cotton core 2 is extended outside the tapering point of sleeve 1 through hole;Sleeve 1
Cylindrical end afterbody is fixed with the closing cover 5 for sealing physiological saline cavity 3, and connects between sleeve 1 and closing cover 5 for screw thread
Connect;The circuit switch run through first 4 is fixed with closing cover 5, and physiological saline cavity is fixed in one end of circuit switch first 4
In 3;The diameter of cotton core 2 and the internal diameter in the tapered stomidium hole of sleeve 1 are equal in magnitude;The length of sleeve 1 is 18-20mm;Cotton core 2 prolongs
The length for stretching in sleeve 1 is 0.9-1.1mm.The area of the circular cross section of cotton core 2 is 2.9-3.5mm2。
Present apparatus application method:
1. being irrigated into device physiological saline cavity 3 after physiological saline, the head end of cotton core 2 is soaked and not dripped;Cotton core is dashed forward
Go out the head end of sleeve 1;
2. pair experimental animal is given before galvanic current stimulation is fixed on brain area institute to be stimulated by the ledge of present apparatus cotton core 2
Corresponding skull surface, if long-time stimulus can increase electrode stability and fastness, Zhi Houli by dentistry cement reaction
Physiological saline is irrigated into device with syringe and closed with closing cover 5, to prevent that liquid evaporation causes electrode cotton core to do in electrode
The increase of dry and electrode impedance;
3. circuit switch first 4 is connected to the stimulation circuit connected with silver wire, by adjusting stimulator parameter when stimulating
And open stimulus modality and can start electro photoluminescence, reference electrode can use the silicon rubber electrode of Clinical practice, be pasted on experiment dynamic
Thorax abdomen after thing moistening.
The present apparatus substitutes the rigid head end of traditional metal electrodes by using the head end of cotton core 2 of plasticity, to avoid electrode
The impedance increase caused with skull loose contact or imprecision of fitting, adds physiological saline in physiological saline cavity 3 when using,
The present apparatus is using physiological saline as conducting medium, and electric conductivity is well and stably, it is to avoid the electric conductivity that metal electrode oxidation is caused
Change, and then ensure the stability of direct current during long-time stimulus, can effectively exclude weak current change or current noise pair
The interference of experimental study, improves the accuracy of direct current research;The head end limited size of cotton core 2 of present apparatus electrode is in sleeve 1
Tapering point, cotton core 2 is diametrically stable, so electrode contact area is stably and controllable;" recessed " the shape end of device electrode is more traditional simultaneously
" convex " the shape end of metal electrode is more compact, greatly shortens electrode total length, can be prevented effectively from electrode long dynamic to experiment
The interference of thing normal life and the stability and fastness for adding electrode fixation, are that electrode is fixed on experiment by bone cement for a long time
Animal skull surface creates more easily condition, disclosure satisfy that the long-term need through cranium galvanic current stimulation of minitype animal experiment
Will;In addition, the sleeve of the present apparatus is plastic sleeve, material source is extensively, with low cost and easily prepared, and can repeat to make
With than the more human-oriented practicality of metal electrode of high cost.Due to being threadedly coupled between sleeve 1 and closing cover 5, so as to improve
The sealing of device, it is to avoid the outflow of physiological saline when using.
The plain conductor of traditional electrode end is that " convex " goes out structure, and " recessed " shape structure is typically used when electrode is connected into circuit
Pliers be clipped in the middle, so as to cause such electrode overall partially long.Present apparatus electrode middle cavity is " recessed " shape structure, uses electricity
During pole, physiological saline is injected to middle cavity, afterwards inserted " convex " shape wire in " recessed " shape cavity full of physiological saline,
This design causes the total length of electrode substantially to shorten, so as to take electroded experimental animal normal life to the head length phase, such as
Bow feed or drinking-water etc. interference significantly reduce.In addition, when the device is fixed on laboratory animal head, the noncontinuous electrode arm of force
Corresponding to shorten, when experimental animal is movable, electrode is difficult for drop-off.The need for the device can preferably meet growing animal experiment, fit
In being widely applied and extensive use.
Claims (6)
1. a kind of be used for cup-shape electrode of the minitype animal experiment through cranium galvanic current stimulation, it is characterised in that:Including sleeve (1), cotton
Core (2) and the physiological saline cavity (3) for being installed on sleeve (1) inside;One end of sleeve (1) is in cylinder, and the other end is tapered,
And tapered tip opens up hole;One end of cotton core (2) and one end phase for the physiological saline cavity (3) being fixed in sleeve (1)
Connect, the other end of cotton core (2) is extended outside sleeve (1) tapering point through hole;The cylindrical end afterbody of sleeve (1), which is fixed with, to be used for
Seal the closing cover (5) of physiological saline cavity (3);The circuit switch head (4) run through, and electricity are fixed with closing cover (5)
One end of road adapter (4) is fixed in physiological saline cavity (3).
2. it is according to claim 1 a kind of for cup-shape electrode of the minitype animal experiment through cranium galvanic current stimulation, its feature
It is:The diameter of described cotton core (2) and the internal diameter in the tapered stomidium hole of sleeve (1) are equal in magnitude.
3. it is according to claim 1 a kind of for cup-shape electrode of the minitype animal experiment through cranium galvanic current stimulation, its feature
It is:The length of described sleeve (1) is 18-20mm.
4. it is according to claim 1 a kind of for cup-shape electrode of the minitype animal experiment through cranium galvanic current stimulation, its feature
It is:The length that described cotton core (2) extends sleeve (1) is 0.9-1.1mm.
5. it is according to claim 1 a kind of for cup-shape electrode of the minitype animal experiment through cranium galvanic current stimulation, its feature
It is:The area of described cotton core (2) circular cross section is 2.9-3.5mm2。
6. it is according to claim 1 a kind of for cup-shape electrode of the minitype animal experiment through cranium galvanic current stimulation, its feature
It is:It is connected through a screw thread between described sleeve (1) and closing cover (5).
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CN201621336247.1U CN206613034U (en) | 2016-12-07 | 2016-12-07 | It is a kind of to be used for cup-shape electrode of the minitype animal experiment through cranium galvanic current stimulation |
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CN201621336247.1U CN206613034U (en) | 2016-12-07 | 2016-12-07 | It is a kind of to be used for cup-shape electrode of the minitype animal experiment through cranium galvanic current stimulation |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN110215609A (en) * | 2019-06-28 | 2019-09-10 | 清华大学天津高端装备研究院 | A kind of pulsed magnetic field bracket and electromagnetic stimulation device for experimental animal |
CN110811628A (en) * | 2018-08-14 | 2020-02-21 | 智识互通(苏州)生物科技有限公司 | Gait image analysis system with synchronous transcranial direct current stimulation function |
CN111729191A (en) * | 2020-06-10 | 2020-10-02 | 北京品驰医疗设备有限公司 | Animal vagus nerve stimulation system and manufacturing method thereof |
-
2016
- 2016-12-07 CN CN201621336247.1U patent/CN206613034U/en not_active Expired - Fee Related
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110811628A (en) * | 2018-08-14 | 2020-02-21 | 智识互通(苏州)生物科技有限公司 | Gait image analysis system with synchronous transcranial direct current stimulation function |
CN110215609A (en) * | 2019-06-28 | 2019-09-10 | 清华大学天津高端装备研究院 | A kind of pulsed magnetic field bracket and electromagnetic stimulation device for experimental animal |
CN111729191A (en) * | 2020-06-10 | 2020-10-02 | 北京品驰医疗设备有限公司 | Animal vagus nerve stimulation system and manufacturing method thereof |
CN111729191B (en) * | 2020-06-10 | 2023-09-26 | 北京品驰医疗设备有限公司 | Small animal vagus nerve stimulation system and manufacturing method thereof |
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