CN206473605U - A kind of blood component separation device - Google Patents
A kind of blood component separation device Download PDFInfo
- Publication number
- CN206473605U CN206473605U CN201621232614.3U CN201621232614U CN206473605U CN 206473605 U CN206473605 U CN 206473605U CN 201621232614 U CN201621232614 U CN 201621232614U CN 206473605 U CN206473605 U CN 206473605U
- Authority
- CN
- China
- Prior art keywords
- blood
- filter
- liquid storing
- storing bag
- filter mechanism
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- External Artificial Organs (AREA)
Abstract
The utility model discloses a kind of blood component separation device, for separating the red blood cell in blood, blood platelet and blood plasma, including the first liquid storing bag for storing blood, the first filter mechanism for filtering blood connected with the first liquid storing bag, the blood ingredient separator connected with the first filter mechanism, being used in blood ingredient separator filters blood platelet and blood plasma to obtain the second filter mechanism of red blood cell, it is used to filtered plasma obtain hematoblastic 3rd filter mechanism in blood ingredient separator, the second liquid storing bag for being used to deposit remaining blood plasma after filtering connected with blood ingredient separator, 3rd filter mechanism is located at the lower section of the second filter mechanism.The utility model device, using leukocyte depletion filter filtrating leukocytes, red blood cell, blood platelet and blood plasma is isolated using Novel hollow fibrous material or New Blood filter material under the conditions of natural gravity.The installation cost is cheap, operation is simple, and the blood constituent of preparation meets national standard.
Description
Technical field
The utility model is related to a kind of blood component separation device.
Background technology
Scientific and reasonable is one of World Health Organization's safe transfusion four major strategies with blood, and its core content is exactly that composition is defeated
Blood.Blood constituent prepare be substantially all using after mechanical centrifugal using plasma-separating clip or blood component separator carry out red blood cell and
The separation of blood plasma, its advantage is simple and quick and batch operation.But, there is following defect in current methods：
Prepared blood constituent quality is influenceed very big by parameter of noncentricity (rotating speed, temperature, time, acceleration, deceleration).
Such as when centrifugal force is 3840g, during 12 min of centrifugation, packed cell volume is 0.47 ± 0.03；When centrifugal force is 2475g, centrifugation
During 10min, packed cell volume value then becomes 0.43 ± 0.03.
Centrifugation has an impact to red cell morphology, fragility increase, could recover after 24h.
Excessive centrifugation makes red blood cell be caused intra-erythrocyte Cucumber to occur to exchange and make content by excessive compression
Change；Because the activity of Cucumber particularly enzyme in serum occurs for excessive centrifugation and the content of Cucumber is caused to change
Become, influence follow-up testing result.
Centrifugation causes blood bag damaged, causes Blood discarding.Blood bag is damaged, and the ratio scrapped that damaged oozing of blood is caused can be high
Up to 8.21%.
It is high that blood constituent prepares cost：Need instrument and equipment（Centrifuge/component separator）, manpower（Professional technique people
Member）, the resource such as electric power.
The operating space of cleaning is needed, is not suitable in the wild（Wartime, relieve the people in stricken areas, anti-terrorism）, carry out on blood-collecting car.
Utility model content
The purpose of this utility model is to provide a kind of blood component separation device, without using centrifuge and blood constituent point
Disembark, under the conditions of natural gravity, blood is separated by filtration using filter mechanism.
To reach above-mentioned purpose, the technical solution adopted in the utility model is：
A kind of blood component separation device, for separating the red blood cell in blood, blood platelet and blood plasma, described device bag
Include：
The first liquid storing bag for storing blood；
The first filter mechanism for filtering blood connected with first liquid storing bag；
The blood ingredient separator for being used to store the blood being filtrated to get connected with first filter mechanism；
Being used in the blood ingredient separator filters blood platelet and blood plasma to obtain the second filtering of red blood cell
Mechanism；
It is used for filtered plasma in the blood ingredient separator to obtain hematoblastic 3rd filter mechanism, it is described
3rd filter mechanism is located at the lower section of second filter mechanism；
The second liquid storing bag for being used to deposit remaining blood plasma after filtering connected with the blood ingredient separator.
Preferably, first filter mechanism includes being used to filter micro- poly- successively along the direction away from first liquid storing bag
Micro- aggressiveness filter, the leucocyte filter for leukocyte depletion of body.
It is highly preferred that micro- aggressiveness filter is nylon filter, the aperture of micro- aggressiveness filter is in 30-60um
Between.
It is highly preferred that the leucocyte filter is formed by stacking by multilayer modification nonwoven cloth.
Preferably, second filter mechanism include be used for filter blood platelet and blood plasma with obtain red blood cell filter,
The 3rd liquid storing bag for being used to deposit the red blood cell being filtrated to get connected with the blood ingredient separator.
It is highly preferred that the filter is the first screen pack, first screen pack is nylon filter, first mistake
The aperture of filter screen is between 4-6um.
It is highly preferred that the filter is the first filter membrane, first filter membrane is the doughnut mistake of distribution of taking the shape of the letter U
Chimney filter film, the aperture of first filter membrane is between 4-6um, and the caliber of first filter membrane is between 0.1-1mm.
Preferably, the 3rd filter mechanism includes being used for filtered plasma obtaining hematoblastic second screen pack and institute
State hematoblastic 4th liquid storing bag that storage is filtrated to get that is used for of blood ingredient separator connection, the hole of second screen pack
Footpath is between 0.8-1.2um.
Preferably, described device also include blood sampling mechanism, the blood sampling mechanism include blood taking needle, respectively with the blood taking needle
The blood sampling conduit connected with first liquid storing bag, the sampler bag connected with first liquid storing bag.
Preferably, described device is also included located at the stream between first filter mechanism and the blood ingredient separator
Measure adjuster.
Due to the utilization of above-mentioned technical proposal, the utility model has following advantages compared with prior art：This practicality is new
A kind of blood component separation device of type, under the conditions of natural gravity, using leukocyte depletion filter filtrating leukocytes, using Novel hollow
Fibrous material or New Blood filter material isolate red blood cell, blood platelet and blood plasma.The installation cost is cheap, operation letter
Easily, compact, easy to carry, transitory efficient, not contaminated, can keep blood form and original cell bio-activity.
Brief description of the drawings
Accompanying drawing 1 is the structural representation one of the utility model device；
Accompanying drawing 2 is the structural representation two of the utility model device；
Accompanying drawing 3 is the structural representation of hanger bracket.
Wherein：1st, the first liquid storing bag；2nd, blood ingredient separator；3rd, the second liquid storing bag；4th, micro- aggressiveness filter；5th, it is white thin
Born of the same parents' filter；6th, the 3rd liquid storing bag；7th, the first screen pack；8th, the first filter membrane；9th, the second screen pack；10th, the 4th liquid storing bag；
11st, blood taking needle；12nd, blood sampling conduit；13rd, sampler bag；14th, flow regulator；15th, the first flow-stopping clip；16th, the second flow-stopping clip；17、
3rd flow-stopping clip；18th, the 4th flow-stopping clip；19th, the 5th flow-stopping clip；20th, the 6th flow-stopping clip；21st, hanger bracket；22nd, drain tap.
Embodiment
Come to be further elaborated the technical solution of the utility model below in conjunction with the accompanying drawings.
Referring to shown in Fig. 1-2, above-mentioned a kind of blood component separation device, for separating the red blood cell in blood, blood platelet
And blood plasma, the device includes：
The first liquid storing bag 1 for storing blood；
Blood sampling mechanism, blood sampling mechanism is led including blood taking needle 11, the blood sampling connected respectively with the liquid storing bag 1 of blood taking needle 11 and first
Pipe 12, the sampler bag 13 connected with the first liquid storing bag 1, located at blood sampling conduit 12 on the first flow-stopping clip 15, located at sampler bag 13
And first the second flow-stopping clip 16 between liquid storing bag 1；
Connected with the first liquid storing bag 1 for the first filter mechanism of filtering blood, located at the first filter mechanism and blood
The 3rd flow-stopping clip 17 between flow regulator 14, the first liquid storing bag 1 and the first filter mechanism between composition separator；
The blood ingredient separator 2 for being used to store the blood being filtrated to get connected with the first filter mechanism；
Being used in blood ingredient separator 2 filters blood platelet and blood plasma to obtain the second filter of red blood cell
Structure；
It is used to filtered plasma obtain hematoblastic 3rd filter mechanism, the 3rd mistake in blood ingredient separator 2
Filter structure is located at the lower section of the second filter mechanism；
What is connected with blood ingredient separator 2 is used for the second liquid storing bag 3 of remaining blood plasma after storage filtering, located at blood
The 4th flow-stopping clip 18 between the liquid storing bag 3 of composition separator 2 and second.
Above-mentioned first filter mechanism includes the micro- aggressiveness for being used to filter micro- aggressiveness along the direction away from the first liquid storing bag 1 successively
Filter 4, the leucocyte filter 5 for leukocyte depletion.
The upper end of blood ingredient separator 2 and micro- aggressiveness filter 4 is equipped with drain tap 22, and the drain tap 22 is used for
Make blood smooth outflow therein, the problem of will not stagnating and block.
Micro- aggressiveness filter 4 is nylon filter, and the aperture of micro- aggressiveness filter 4 is 30um, micro- aggressiveness filtering
The cell fragment that device 4 is used in filtering blood, large particulate matter and albuminate etc..
The leucocyte filter 5 is formed by stacking using using the multi-layer resinous fibre modification non-woven fabrics cloth of PBT, for removing blood
Leucocyte in liquid, and basic guarantee remaining haemocyte bioactivity.
Above-mentioned second filter mechanism include be used for filter blood platelet and blood plasma with obtain red blood cell filter, with blood into
What point separator 2 was connected, which be used for, deposits the 3rd liquid storing bag 6 of the red blood cell being filtrated to get, located at blood ingredient separator 2 and the
The 5th flow-stopping clip 19 between three liquid storing bags 6.
In the embodiment shown in Figure 2, the filter is the first screen pack 7, and first screen pack 7 is nylon filter,
The aperture of first screen pack 7 is 5um.The undulate of first screen pack 7, is set, by increasing capacitance it is possible to increase filter area by this,
Make filter effect more preferable.
In the embodiment shown in fig. 1, the filter is the first filter membrane 8, and first filter membrane 8 is the distribution that takes the shape of the letter U
Hollow fibre filtering periosteum, the aperture of first filter membrane 8 is 5um, and the caliber of first filter membrane 8 is for 0.8mm, and this first
Filter membrane 8 includes PS membrane, poly (ether sulfone) film, triacetate cellulose membrane etc..First filter mechanism and the 3rd liquid storing bag 6 respectively with U-shaped
The two ends of the hollow fibre filtering periosteum of distribution are connected.
Above-mentioned 3rd filter mechanism includes being used for filtered plasma obtaining hematoblastic second screen pack 9 and blood constituent
Separator 2 connect be used for deposit be filtrated to get hematoblastic 4th liquid storing bag 10, located at blood ingredient separator 2 and the 4th
The 6th flow-stopping clip 20 between liquid storing bag 10, the aperture of the second screen pack 9 is 1um.The undulate of second screen pack 9, passes through
This is set, by increasing capacitance it is possible to increase filter area, makes filter effect more preferable.
After tested, the blood constituent prepared by the device meets national standard（GB18469-2012）.
The course of work of lower the present embodiment is illustrated in detail below：
The protective case of blood taking needle 11 is taken out, the first flow-stopping clip 15 on blood sampling conduit 12 is opened, closes remaining flow-stopping clip, twist into two parts
The interface of blood sampling conduit 12, carries out blood collection.The blood sampling of heat seal immediately conduit 12 after collection is finished, twists into two parts connection sampler bag 13
Interface, while opening the second flow-stopping clip 16, carries out blood sampling.When the storage of heat seal sampler bag 13 and first immediately after end to be sampled
Conduit between liquid bag 1, so far, blood collection procedure terminates.
In the embodiment shown in fig. 1, the first liquid storing bag 1, blood ingredient separator 2, the second liquid storing bag the 3, the 3rd are stored up
Liquid the 6, the 4th liquid storing bag 10 of bag is hung to the corresponding position on the hanger bracket 21 shown in Fig. 3 respectively, makes its entirety perpendicular to ground
Face, twists into two parts the connector of the first liquid storing bag 1, opens the 3rd flow-stopping clip 17, the 4th flow-stopping clip 18, the 5th flow-stopping clip 19, closes the
Six flow-stopping clips 20, while twisting into two parts the connecting interface of the 3rd liquid storing bag 6, adjust flow regulator 14, blood flows through micro- aggressiveness filtering
Device 4 removes the large particulate matter and deformation protein in blood, passes through leucocyte filter 5 and can remove leucocyte.First filtering
Red blood cell, blood platelet and blood plasma after mechanism filtering enter blood ingredient separator 2.Pass through the hollow fibre of U-shaped of the first filter membrane 8
Dimensional filter layer can retain red blood cell, red blood cell is flowed directly into the 3rd liquid storing bag 6 with Precerving liquid, through the first filter membrane 8
The blood stream of filtering is flowed downward, and blood platelet can be retained by the second screen pack 9, and blood plasma directly can be entered by the second screen pack 9
Enter the second liquid storing bag 3.After the time of setting, blood can all be filtered and finished, and now open the 6th flow-stopping clip 20, twist into two parts the
Interface on four liquid storing bags 10, tilts blood ingredient separator 2, and the blood platelet that filtering is finished is imported in the 4th liquid storing bag 10,
So far component blood collection is finished, and each conduit of heat seal, component blood can be used directly or preserve.
In the embodiment shown in Figure 2, the first liquid storing bag 1, blood ingredient separator 2, the second liquid storing bag the 3, the 3rd are stored up
Liquid the 6, the 4th liquid storing bag 10 of bag is hung to the corresponding position on the hanger bracket 21 shown in Fig. 3 respectively, makes its entirety perpendicular to ground
Face, twists into two parts the connector of the first liquid storing bag 1, opens the 3rd flow-stopping clip 17, the 4th flow-stopping clip 18, closes the 5th flow-stopping clip 19, the
Six flow-stopping clips 20, adjust flow regulator 14, and blood flows through large particulate matter and deformation in the micro- removal of aggressiveness filter 4 blood
Albumen, passes through leucocyte filter 5 and can remove leucocyte.Red blood cell, blood platelet and blood plasma after the filtering of first filter mechanism
Into blood ingredient separator 2.Red blood cell can be retained by the first screen pack 7, the blood stream filtered through the first screen pack 7 is downward
Flowing, blood platelet can be retained by the second screen pack 9, and blood plasma directly can enter the second liquid storing bag 3 by the second screen pack 9.Through
After the time for crossing setting, blood can all be filtered and finished, and now opened the 5th flow-stopping clip 19, the 6th flow-stopping clip 20, twisted into two parts the 3rd
Interface on liquid storing bag 6, the 4th liquid storing bag 10, the red blood cell that filtering is finished is imported in the 3rd liquid storing bag 6, while will filter
Complete blood platelet is imported in the 4th liquid storing bag 10, and so far component blood collection is finished, and each conduit of heat seal, component blood can be used directly
Or preserve.
Above-described embodiment is only to illustrate technical concepts and features of the present utility model, and its object is to allow be familiar with technique
Personage can understand content of the present utility model and be carried out, protection domain of the present utility model can not be limited with this,
All equivalent change or modifications made according to the utility model Spirit Essence, should all cover in protection domain of the present utility model
It is interior.
Claims (10)
1. a kind of blood component separation device, for separating the red blood cell in blood, blood platelet and blood plasma, it is characterised in that：Institute
Stating device includes：
The first liquid storing bag for storing blood；
The first filter mechanism for filtering blood connected with first liquid storing bag；
The blood ingredient separator for being used to store the blood being filtrated to get connected with first filter mechanism；
Being used in the blood ingredient separator filters blood platelet and blood plasma to obtain the second filter mechanism of red blood cell；
It is used to filtered plasma obtain hematoblastic 3rd filter mechanism, the described 3rd in the blood ingredient separator
Filter mechanism is located at the lower section of second filter mechanism；
The second liquid storing bag for being used to deposit remaining blood plasma after filtering connected with the blood ingredient separator.
2. a kind of blood component separation device according to claim 1, it is characterised in that：First filter mechanism is along far
Direction from first liquid storing bag includes being used to filter micro- aggressiveness filter of micro- aggressiveness, for the white of leukocyte depletion successively
Cell filter.
3. a kind of blood component separation device according to claim 2, it is characterised in that：Micro- aggressiveness filter is Buddhist nun
Imperial screen pack, the aperture of micro- aggressiveness filter is between 30-60um.
4. a kind of blood component separation device according to claim 2, it is characterised in that：The leucocyte filter is by more
Layer modification nonwoven cloth is formed by stacking.
5. a kind of blood component separation device according to claim 1, it is characterised in that：Second filter mechanism includes
For filtering blood platelet and blood plasma to obtain the filter of red blood cell, being used for of connecting with the blood ingredient separator deposited
Filter the 3rd liquid storing bag of obtained red blood cell.
6. a kind of blood component separation device according to claim 5, it is characterised in that：The filter is the first filtering
Net, first screen pack is nylon filter, and the aperture of first screen pack is between 4-6um.
7. a kind of blood component separation device according to claim 5, it is characterised in that：The filter is the first filtering
Film, first filter membrane is the hollow fibre filtering periosteum of distribution of taking the shape of the letter U, the aperture of first filter membrane 4-6um it
Between, the caliber of first filter membrane is between 0.1-1mm.
8. a kind of blood component separation device according to claim 1, it is characterised in that：3rd filter mechanism includes
For filtered plasma to obtain hematoblastic second screen pack, being filtered for storage of connecting with the blood ingredient separator
Hematoblastic 4th liquid storing bag arrived, the aperture of second screen pack is between 0.8-1.2um.
9. a kind of blood component separation device according to claim 1, it is characterised in that：Described device also includes blood sampling machine
Structure, the blood sampling mechanism includes blood taking needle, the blood sampling conduit connected respectively with the blood taking needle and first liquid storing bag and institute
State the sampler bag of the first liquid storing bag connection.
10. a kind of blood component separation device according to claim 1, it is characterised in that：Described device also includes being located at
Flow regulator between first filter mechanism and the blood ingredient separator.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621232614.3U CN206473605U (en) | 2016-11-17 | 2016-11-17 | A kind of blood component separation device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621232614.3U CN206473605U (en) | 2016-11-17 | 2016-11-17 | A kind of blood component separation device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206473605U true CN206473605U (en) | 2017-09-08 |
Family
ID=59755950
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201621232614.3U Active CN206473605U (en) | 2016-11-17 | 2016-11-17 | A kind of blood component separation device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN206473605U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106621544A (en) * | 2016-11-17 | 2017-05-10 | 张家港高品诚医械科技有限公司 | Blood component separation device and blood component separation method |
-
2016
- 2016-11-17 CN CN201621232614.3U patent/CN206473605U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106621544A (en) * | 2016-11-17 | 2017-05-10 | 张家港高品诚医械科技有限公司 | Blood component separation device and blood component separation method |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP1267990B1 (en) | Systems and methods for collecting leukocyte-reduced blood components, including plasma that is free or virtually free of cellular blood species | |
| CN106621544A (en) | Blood component separation device and blood component separation method | |
| GB2360715A (en) | Membrane based molecule separator | |
| CN206473605U (en) | A kind of blood component separation device | |
| JPWO2016047444A1 (en) | Cell separation material and cell separation method | |
| CN103962194A (en) | Excrement liquidizing and filtering test tube | |
| CN202397870U (en) | Blood separating device | |
| CN202740489U (en) | Blood filter and virus inactivation blood sampling union bag | |
| CN205907261U (en) | Circulation tumor cells autosegregation device | |
| CN103861161B (en) | The preparation method of Washed Red Blood Cells device and Washed Red Blood Cells | |
| CN107551338A (en) | Disposable cell and slurry separation method and separator | |
| CN203184032U (en) | Liquidized defecate filtering test tube | |
| CN216005845U (en) | Microporous filter membrane string bag for direct dehydration and embedding after cell particles are obtained by centrifugation | |
| CN209934477U (en) | Quick tip plasma collector | |
| CN209128435U (en) | It is a kind of with tissue grinder and the unicellular centrifuge tube that function is collected by filtration | |
| RU2285543C2 (en) | Device for removing gel inclusions, micro aggregate particles and leukocytes from blood products | |
| JPH0614968B2 (en) | Leukocyte capture and separation device | |
| CN2703526Y (en) | Blood-cell separator | |
| CN203107801U (en) | Red blood cell washing device | |
| CN112834743A (en) | Cotton swab detection device capable of rapidly collecting AIDS virus | |
| CN206890614U (en) | A kind of lampblack absorber with oil absorptive function | |
| CN201271399Y (en) | Filtering equipment for removing leucocyte from soft mass blood ingredient | |
| CN106860480A (en) | A kind of blood platelet and the preparation method containing hematoblastic preparation | |
| JPS6326089B2 (en) | ||
| CN201220009Y (en) | Disposable soft core leucocyte-removing filter |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |