CN206337252U - A kind of magnetic bionanoparticles method extracts serum-virus nucleic acid reagent box - Google Patents
A kind of magnetic bionanoparticles method extracts serum-virus nucleic acid reagent box Download PDFInfo
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- CN206337252U CN206337252U CN201621066420.0U CN201621066420U CN206337252U CN 206337252 U CN206337252 U CN 206337252U CN 201621066420 U CN201621066420 U CN 201621066420U CN 206337252 U CN206337252 U CN 206337252U
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Abstract
The utility model provides a kind of magnetic bionanoparticles method and extracts serum-virus nucleic acid reagent box, including box body and the lid that is hinged with box body, and the box body top is provided with the first accommodating chamber, the first accommodating chamber and is placed with some reagent bottles；It is provided with below first accommodating chamber in the second accommodating chamber, the second accommodating chamber and is provided with centrifuge tube shelf, the centrifuge tube shelf is pivotally connected with the box body；The box body bottom is provided with the first slot extended laterally, first slot and is inserted with magnetic frame；The centrifuge tube shelf is equipped with some centrifuge tube jacks with the magnetic frame surface；The cover side wall is provided with elastic insert close to the side of the accommodating chamber.The magnetic bionanoparticles method that the utility model is provided extracts serum-virus nucleic acid reagent box, magnetic frame and centrifuge tube shelf are combined as a whole with box body, can directly be extracted out when using, is not required to additionally prepare relevant device, make experimental implementation more simple and efficient, have the advantages that vdiverse in function, easy to use.
Description
Technical field
The utility model is related to biological technical field, and more particularly to a kind of magnetic bionanoparticles method extracts serum-virus nucleic acid
Kit.
Background technology
Since magnetic separation technique based on micro-nano magnetic bead is born from the eighties in last century, life science and face
More and more applied in the fields such as bed detection.Beads enrichment technical operation is simple, and strong adaptability was both manually operable,
Automation equipment can be applied to very well to operate.Magnetic bionanoparticles be one by Microbe synthesis magnetic nanoparticle, be natural
Biomagnetism nano material, with the incomparable advantage of some artificial synthesized magnetic beads.Utilize technique for gene engineering or knot
Chemical modification technology is closed, special biologically functional molecule can be shown in magnetic bionanoparticles surface orientation, or be coated with other materials
Such as silylation material so that magnetic bionanoparticles can be used in the purifying and extraction of common nucleic acid and specific nucleic acid molecule.
Paramagnetic particle method, which extracts sample of nucleic acid, has important application value in life science and field of medical examination, but is directed to
Its DNA nucleic acid compositions of the sample extraction of separate sources need to use different processing methods, still need to be developed maturation, standard,
Easy to operate kit.
Utility model content
In order to solve the above-mentioned technical problem, the utility model provides a kind of magnetic bionanoparticles method and extracts serum-virus core
Acid reagent box, the kit is simple to operate, carries out nucleic acid purification specifically designed for the sample of particular source, can be supplied to different demands
The field such as scientific research or inspection and quarantine is used.
The utility model concrete technical scheme is as follows：
The utility model provides a kind of magnetic bionanoparticles method and extracts serum-virus nucleic acid reagent box, including box body and box
Lid, the lid is connected by hinge with the box body, and the box body top is provided with the first accommodating chamber, first accommodating chamber
It is placed with some reagent bottles；It is provided with below first accommodating chamber in the second accommodating chamber, second accommodating chamber and is provided with centrifuge tube
Frame, the centrifuge tube shelf is pivotally connected with the box body；The box body bottom is provided with the first slot extended laterally, described first
Magnetic frame is inserted with slot；The centrifuge tube shelf is equipped with some centrifuge tube jacks with the magnetic frame surface；The lid
Side wall is provided with elastic insert close to the side of the accommodating chamber.
Further, the first accommodating chamber bottom is provided with some grooves, and some reagent bottles are plugged in the groove
It is interior.
Further, the reagent bottle includes the first reagent bottle, the use for being used to hold lyophilized magnetic bionanoparticles reagent
In holding the second reagent bottle of freeze-dried reagent dilution buffer, the 3rd reagent bottle for holding serum lysis buffer, be used for
Hold the 4th reagent bottle of nucleic acid extraction Contrast agent, the 5th reagent bottle for holding lavation buffer solution I, for holding washing
Buffer solution II the 6th reagent bottle and the 7th reagent bottle for holding Dnase/Rnase-Free elution buffers.
Further, side of the cover side wall away from the hinge is provided with some deep-slotted chip breakers.
Further, it is additionally provided with the middle part of the box body in the second slot, second slot and is inserted with drawer, the drawer
Inside it is placed with the centrifuge tube being adapted with the centrifuge tube jack.
Further, it is equipped with handle on the lid, the centrifuge tube shelf, the magnetic frame and the drawer side wall.
Further, described centrifuge tube shelf one end offers in longitudinal through hole, the through hole and is inserted with connecting shaft, described
Centrifuge tube shelf is pivotally connected by the connecting shaft with the box body.
The beneficial effects of the utility model are as follows：The magnetic bionanoparticles method that the utility model is provided extracts serum-virus core
Acid reagent box, has the advantages that vdiverse in function, easy to use.Magnetic frame and centrifuge tube shelf are combined with box body, one is made
Body, can directly extract out when using and use, and be not required to additionally prepare relevant device；And the connected mode plugged is so that user can
, can when using to adjust the length that magnetic frame is extracted out from box body as needed, and because centrifuge tube shelf and box body are pivotally connected
To adjust the angle of centrifuge tube shelf, using more convenient；Cover side wall is provided with deep-slotted chip breaker, available for suspension liquid-transfering gun, in experiment
It can take at any time.Designed more than, make experimental implementation more simple and efficient, significantly improve the efficiency and success rate of experiment.
Brief description of the drawings
Fig. 1 is a kind of structural representation of magnetic bionanoparticles method extraction serum-virus nucleic acid reagent box described in embodiment 1
Figure；
Fig. 2 is that a kind of magnetic bionanoparticles method described in embodiment 2 extracts accommodating chamber in serum-virus nucleic acid reagent box
Structural representation；
Fig. 3 is that a kind of magnetic bionanoparticles method described in embodiment 3 extracts deep-slotted chip breaker in serum-virus nucleic acid reagent box
Top view；
Fig. 4 is that a kind of magnetic bionanoparticles method described in embodiment 3 extracts deep-slotted chip breaker in serum-virus nucleic acid reagent box
Front view；
Fig. 5 is a kind of structural representation of magnetic bionanoparticles method extraction serum-virus nucleic acid reagent box described in embodiment 4
Figure.
Wherein：1st, box body；101 first accommodating chambers；102nd, reagent bottle；1021st, the first reagent bottle；1022nd, the second reagent bottle；
1023rd, the 3rd reagent bottle；1024th, the 4th reagent bottle；1025th, the 5th reagent bottle；1026th, the 6th reagent bottle；1027th, the 7th reagent
Bottle；103rd, the second accommodating chamber；104th, centrifuge tube shelf；105th, the first slot；106th, magnetic frame；107th, centrifuge tube jack；108th, it is recessed
Groove；109th, the second slot；110th, drawer；111st, centrifuge tube；112nd, handle；113rd, connecting shaft；2nd, lid；201st, elastic insert；
202nd, deep-slotted chip breaker.
Embodiment
The utility model is described in further detail with following examples below in conjunction with the accompanying drawings.
Embodiment 1
As shown in figure 1, the utility model embodiment 1, which provides a kind of magnetic bionanoparticles method, extracts the examination of serum-virus nucleic acid
Agent box, including box body 1 and lid 2, the lid 2 are connected by hinge with the box body 1, and the top of box body 1 is provided with first
Some reagent bottles 102 are placed with accommodating chamber 101, first accommodating chamber；The lower section of first accommodating chamber 101 holds provided with second
Receive chamber 103, centrifuge tube shelf 104 is provided with second accommodating chamber 103, the centrifuge tube shelf 104 is pivoted with the box body 1 to be connected
Connect；The bottom of box body 1 is provided with the first slot 105 extended laterally, first slot 105 and is inserted with magnetic frame 106；Institute
State centrifuge tube shelf 104 and be equipped with some centrifuge tube jacks 107 with the surface of magnetic frame 106；The side wall of lid 2 is close to described
The side of accommodating chamber 101 is provided with elastic insert 201.
Centrifuge tube shelf 104 and magnetic frame 106 are located in box body 1, one is made, can be directly by centrifugation when using
Pipe support 104 and magnetic frame 106, which are extracted out, to be used, and is not required to additionally prepare relevant device, reduces the scope of activities of experimental implementation, particularly
When sample size is more, the probability of operational error can be substantially reduced with the time and efforts of effectively save user；And insert
If connected mode allow user to adjust the length that magnetic frame 106 is extracted out from box body as needed, and due to centrifugation
Pipe support 104 is pivotally connected with box body 1, and the angle of centrifuge tube shelf 104 can be adjusted when using, using more convenient.Elastic insert
201 effect is to prevent the lid abrasion of reagent bottle 102, and extrudes fixation to reagent bottle 102.
Embodiment 2
As shown in Fig. 2 embodiment 2 provides a kind of magnetic bionanoparticles method on the basis of embodiment 1 extracts serum sickness
Malicious nucleic acid reagent box, the embodiment 2 further defines the bottom of the first accommodating chamber 101 provided with some grooves 108, Ruo Gansuo
Reagent bottle 102 is stated to be plugged in the groove 108.Some reagent bottles 102 include being used to hold lyophilized biological nano magnetic
First reagent bottle 1021 of pearl reagent, the second reagent bottle 1022 for holding freeze-dried reagent dilution buffer, for holding blood
3rd reagent bottle 1023 of clear lysis buffer, the 4th reagent bottle 1024 for holding nucleic acid extraction Contrast agent, for containing
Put lavation buffer solution I the 5th reagent bottle 1025, the 6th reagent bottle 1026 for holding lavation buffer solution II and for containing
Put the 7th reagent bottle 1027 of Dnase/Rnase-Free elution buffers.
Groove 108 is set in the bottom of the first accommodating chamber 101, and reagent bottle 102 is inserted in groove 108, can play solid
It is set for using, puts reagent bottle 102 firm, be difficult to topple over or seepage, it is to avoid the pollution or loss of reagent.Seven reagent bottles
1021-1027 has corresponded to seven steps in experiment respectively, is taken successively when using, and convenience and high-efficiency, avoids mistake.
Embodiment 3
As shown in Figures 3 and 4, embodiment 3 provides a kind of magnetic bionanoparticles method on the basis of embodiment 1 and extracts serum
Viral nucleic acid kit, the embodiment 3 further defines the side of the side wall away from the hinge of lid 2 provided with some arcs
Shape groove 202.
It is near normal state with box body 1 when lid 2 is opened, now can giving a hand the liquid-transfering gun used in experiment
Hang on deep-slotted chip breaker 202；It can at any time be taken in experimentation, and liquid-transfering gun can be made to be kept upright state in the not used time, it is to avoid
Damage liquid-transfering gun；Shelf without additionally preparing suspension liquid-transfering gun, it is easy to use.
Embodiment 4
As shown in figure 5, embodiment 4 provides a kind of magnetic bionanoparticles method rapid extraction matter on the basis of embodiment 1
Grain DNA kits, the embodiment 4 further defines the middle part of box body 1 and is additionally provided with the second slot 109, second slot
It is inserted with 109 in drawer 110, the drawer 110 and is placed with the centrifuge tube 111 being adapted with the centrifuge tube jack 107.Institute
State and be equipped with handle 112 on lid 2, the centrifuge tube shelf 104, the magnetic frame 106 and the side wall of the drawer 110.It is described from
The one end of heart pipe support 104 offers and connecting shaft 113 is inserted with longitudinal through hole, the through hole, and the centrifuge tube shelf 104 passes through institute
Connecting shaft is stated to be pivotally connected with the box body 1.
Drawer 110 is set on box body 1, and is placed with the centrifuge tube 111 being adapted with centrifuge tube jack 107, can when using
It is convenient and swift to take at any time；The drawer 110 plugged can be according to extracting out or push back the need for use, and in drawer 110
Other experimental articles can be placed in the case where not polluted to centrifuge tube 111, the utilization rate of drawer 110 is improved；
Handle 112 is set on lid 2, centrifuge tube shelf 104, magnetic frame 106 and the side wall of drawer 110, lid 2 can be conveniently opened and take out
Centrifuge tube shelf 104, magnetic frame 106 and drawer 110 are drawn, conventional efficient is further improved.
The utility model is not limited to above-mentioned preferred forms, and anyone can draw under enlightenment of the present utility model
Other various forms of products, however, make any change in its shape or structure, it is every that there is same as the present application or phase
Approximate technical scheme, all falls within protection domain of the present utility model.
Claims (7)
1. a kind of magnetic bionanoparticles method extracts serum-virus nucleic acid reagent box, including box body (1) and lid (2), the lid
(2) it is connected by hinge with the box body (1), it is characterised in that box body (1) top is provided with the first accommodating chamber (101), institute
State in the first accommodating chamber (101) and be placed with some reagent bottles (102)；Accommodated below first accommodating chamber (101) provided with second
Centrifuge tube shelf (104), the centrifuge tube shelf (104) and the box body (1) are provided with chamber (103), second accommodating chamber (103)
It is pivotally connected；Box body (1) bottom is provided with the first slot (105) extended laterally, first slot (105) and is inserted with
Magnetic frame (106)；The centrifuge tube shelf (104) is equipped with some centrifuge tube jacks (107) with the magnetic frame (106) surface；
Lid (2) the side wall is provided with elastic insert (201) close to the side of the accommodating chamber (101).
2. magnetic bionanoparticles method as claimed in claim 1 extracts serum-virus nucleic acid reagent box, it is characterised in that described the
One accommodating chamber (101) bottom is provided with some grooves (108), and some reagent bottles (102) are plugged in the groove (108).
3. magnetic bionanoparticles method as claimed in claim 1 or 2 extracts serum-virus nucleic acid reagent box, it is characterised in that if
Doing the reagent bottle (102) includes being used to hold the first reagent bottle (1021) of lyophilized magnetic bionanoparticles reagent, for containing
Put the second reagent bottle (1022) of freeze-dried reagent dilution buffer, the 3rd reagent bottle for holding serum lysis buffer
(1023), for holding the 4th reagent bottle (1024) of nucleic acid extraction Contrast agent, the 5th examination for holding lavation buffer solution I
Agent bottle (1025), the 6th reagent bottle (1026) for holding lavation buffer solution II and for holding elution buffer the 7th
Reagent bottle (1027).
4. magnetic bionanoparticles method as claimed in claim 1 extracts serum-virus nucleic acid reagent box, it is characterised in that the box
Cover side of (2) the side wall away from the hinge and be provided with some deep-slotted chip breakers (202).
5. magnetic bionanoparticles method as claimed in claim 1 extracts serum-virus nucleic acid reagent box, it is characterised in that the box
It is additionally provided with the middle part of body (1) in the second slot (109) extended laterally, second slot (109) and is inserted with drawer (110), institute
State in drawer (110) and be placed with the centrifuge tube (111) being adapted with the centrifuge tube jack (107).
6. magnetic bionanoparticles method as claimed in claim 5 extracts serum-virus nucleic acid reagent box, it is characterised in that the box
Handle (112) is equipped with lid (2), the centrifuge tube shelf (104), the magnetic frame (106) and the drawer (110) side wall.
7. magnetic bionanoparticles method as claimed in claim 1 extracts serum-virus nucleic acid reagent box, it is characterised in that it is described from
Heart pipe support (104) one end offers and connecting shaft (113) is inserted with longitudinal through hole, the through hole, the centrifuge tube shelf (104)
It is pivotally connected by the connecting shaft (113) with the box body (1).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621066420.0U CN206337252U (en) | 2016-09-20 | 2016-09-20 | A kind of magnetic bionanoparticles method extracts serum-virus nucleic acid reagent box |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621066420.0U CN206337252U (en) | 2016-09-20 | 2016-09-20 | A kind of magnetic bionanoparticles method extracts serum-virus nucleic acid reagent box |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206337252U true CN206337252U (en) | 2017-07-18 |
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ID=59299978
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201621066420.0U Active CN206337252U (en) | 2016-09-20 | 2016-09-20 | A kind of magnetic bionanoparticles method extracts serum-virus nucleic acid reagent box |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN206337252U (en) |
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2016
- 2016-09-20 CN CN201621066420.0U patent/CN206337252U/en active Active
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Address after: 102200 Beijing Changping District science and Technology Park, Zhenxing Road, 36, Cage 2, 6, 625, 627, 629, 631, 633, 635, 637, and 637, respectively. Patentee after: The state of Beijing Rongzhi Biological Technology Co. Ltd. Address before: 100098 A02-28, ground floor, 1 building, 13 Dazhong temple, Haidian District, Beijing. Patentee before: The state of Beijing Rongzhi Biological Technology Co. Ltd. |