CN206089660U - Biological nanometer paramagnetic particle method draws viral RNA kit - Google Patents
Biological nanometer paramagnetic particle method draws viral RNA kit Download PDFInfo
- Publication number
- CN206089660U CN206089660U CN201621121301.0U CN201621121301U CN206089660U CN 206089660 U CN206089660 U CN 206089660U CN 201621121301 U CN201621121301 U CN 201621121301U CN 206089660 U CN206089660 U CN 206089660U
- Authority
- CN
- China
- Prior art keywords
- reagent
- box
- magnetic
- kit
- plate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 108020000999 Viral RNA Proteins 0.000 title claims abstract description 14
- 238000000034 method Methods 0.000 title claims abstract description 14
- 239000002245 particle Substances 0.000 title abstract description 3
- 230000005298 paramagnetic effect Effects 0.000 title abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 89
- 230000005291 magnetic effect Effects 0.000 claims abstract description 53
- 239000011324 bead Substances 0.000 claims abstract description 24
- 238000012360 testing method Methods 0.000 claims abstract description 16
- 238000000605 extraction Methods 0.000 claims abstract description 9
- 239000006249 magnetic particle Substances 0.000 claims abstract description 6
- 239000000696 magnetic material Substances 0.000 claims abstract description 5
- 230000003287 optical effect Effects 0.000 claims description 21
- 239000000243 solution Substances 0.000 claims description 10
- 241000700605 Viruses Species 0.000 claims description 6
- 239000011534 wash buffer Substances 0.000 claims description 6
- 230000000149 penetrating effect Effects 0.000 claims description 4
- 239000013024 dilution buffer Substances 0.000 claims description 3
- 239000012149 elution buffer Substances 0.000 claims description 3
- 230000001681 protective effect Effects 0.000 claims description 3
- 102000016911 Deoxyribonucleases Human genes 0.000 claims description 2
- 108010053770 Deoxyribonucleases Proteins 0.000 claims description 2
- 239000007853 buffer solution Substances 0.000 claims 1
- 230000002708 enhancing effect Effects 0.000 claims 1
- 238000009434 installation Methods 0.000 claims 1
- 238000000151 deposition Methods 0.000 abstract description 2
- 238000005516 engineering process Methods 0.000 description 3
- 108020004707 nucleic acids Proteins 0.000 description 3
- 150000007523 nucleic acids Chemical class 0.000 description 3
- 102000039446 nucleic acids Human genes 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 238000000429 assembly Methods 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 238000007385 chemical modification Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000007306 functionalization reaction Methods 0.000 description 1
- 238000010353 genetic engineering Methods 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 239000012139 lysis buffer Substances 0.000 description 1
- 238000007885 magnetic separation Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000002558 medical inspection Methods 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
Landscapes
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The utility model provides a biological nanometer paramagnetic particle method draws viral RNA kit, includes a box body and box cover, separate for the reagent chamber and hold the chamber through the diaphragm in the box body, hold the intracavity be equipped with with box body sliding connection takes out the box, it is equipped with magnetic means in the box to take out, the reagent intracavity is equipped with tool holder and reagent case, magnetic means includes the magnetic sheet, the magnetic sheet is horizontal to be set up take out in the box, be located in taking out the box magnetic sheet underfill has the magnetic particle, even opening there is the test tube hole on the magnetic sheet. This kit is used for drawing viral RNA specially, is provided with the reagent bottle that is used for depositing reagent in this kit, can directly be used for testing through this kit, and kit structure is simple, convenient operation, and the magnetic sheet that magnetic material made can fully be used for adsorbing the biological nanometer magnetic bead, has improved the extraction efficiency, and the practicality is strong.
Description
Technical Field
The utility model belongs to the technical field of it is biological, in particular to virus RNA kit is drawed to biological nanometer magnetic bead method.
Background
Magnetic separation technology based on micro-nano magnetic beads is increasingly applied in the fields of life science research, clinical detection and the like since the birth of the 80 th century. The magnetic bead separation technology is simple to operate, strong in adaptability, capable of being manually operated and well suitable for automatic operation of instruments. The biological nanometer magnetic bead is a magnetic nanometer particle synthesized by microorganisms, is a natural biological magnetic nanometer material, and has incomparable advantages compared with artificial synthetic magnetic beads. By utilizing a genetic engineering technology or combining a chemical modification technology, special biological functional molecules can be directionally displayed on the surface of the biological nano magnetic bead, or other substances such as silylated substances are coated, so that the biological nano magnetic bead can be used for purifying and extracting common nucleic acid and specific nucleic acid molecules.
The magnetic bead method for extracting nucleic acid samples has important application value in the fields of life science and medical inspection, but the extraction of RNA components of samples from different sources is more complicated than the extraction of DNA, because the stability of RNA is not as good as that of DNA, a special treatment method is needed, and mature, standard and convenient-to-operate kits are still to be developed.
SUMMERY OF THE UTILITY MODEL
In order to solve the technical problem, the utility model provides a biological nanometer magnetic bead method draws viral RNA kit, this kit easy operation carries out RNA to the sample of specific source specially and draws, can supply with fields such as scientific research or inspection and quarantine of different demands and use.
The utility model discloses specific technical scheme as follows:
the utility model provides a biological nanometer magnetic bead method draws virus RNA kit, including the box body and with box body one side articulated lid, separate for the reagent chamber and hold the chamber through the diaphragm in the box body, hold the intracavity be equipped with box body sliding connection's the box of taking out, it is equipped with magnetic means in the box to take out, be equipped with tool holder and reagent case in the reagent chamber, the reagent case is located tool holder bottom, place the first reagent bottle that is used for holding freeze-dried biological nanometer magnetic bead reagent in the reagent case respectively, be used for holding the second reagent bottle of freeze-dried reagent dilution buffer, be used for holding the third reagent bottle of schizolysis buffer, be used for holding the fourth reagent bottle of RNA nucleic acid extraction reinforcing reagent, be used for holding fifth reagent bottle of washing buffer I, be used for holding the sixth reagent bottle of washing buffer II, And a seventh reagent bottle for containing a Dnase/Rnase-Free elution buffer solution;
the magnetic device comprises a magnetic plate made of a magnetic material, the magnetic plate is transversely arranged in the drawing box, magnetic particles are filled at the bottom of the magnetic plate in the drawing box, and test tube holes are uniformly formed in the magnetic plate.
Furthermore, fixed plates are symmetrically arranged on two sides of the top in the reagent cavity, hanging plates are connected to the tops of two sides of the tool box, and the hanging plates are lapped on the edges of the fixed plates.
Furthermore, a support plate is transversely arranged in the tool box, jacks for inserting test tubes are uniformly formed in the support plate, a bottom box is arranged at the bottom of the support plate, and a protective pad is arranged in the bottom box.
Furthermore, a lifting mechanism for lifting the reagent storage box is arranged in the reagent cavity, the lifting mechanism comprises lifting components symmetrically arranged at two sides in the reagent cavity, a bottom plate transversely arranged at the bottom of the reagent cavity and a supporting plate transversely arranged between the two lifting components, and the reagent storage box is placed on the supporting plate; wherein,
the lifting assembly comprises a lead screw, an optical axis, a chuck and a motor, the top end of the lead screw is pivotally connected with the fixed plate through a bearing, the bottom end of the lead screw sequentially penetrates through the chuck and the bottom plate to be connected with an output shaft of the motor, the chuck is in threaded connection with the lead screw, the top end of the optical axis is fixed on the fixed plate, and the bottom end of the optical axis penetrates through the chuck and is fixed on the bottom plate;
two ends of the supporting plate are respectively fixed on the clamping heads of the two lifting components.
Preferably, a first mounting hole used for being connected with the lead screw in a penetrating mode and a second mounting hole used for being connected with the optical axis in a penetrating mode are longitudinally formed in the clamping head, threads matched with the lead screw are arranged in the first mounting hole, and the optical axis penetrates through the second mounting hole and is used for limiting the clamping head to move axially along the lead screw.
Preferably, one side of the clamping head close to the support plate is transversely provided with a mounting groove for clamping the support plate.
The utility model has the advantages as follows: the utility model provides a kit is used for extracting virus RNA specially, is provided with the reagent bottle that is used for depositing the reagent in this kit, can directly be used for the experiment through this kit, and kit simple structure, convenient operation, the magnetic sheet that magnetic material made can fully be used for adsorbing biological nanometer magnetic bead, has improved extraction efficiency, and the practicality is strong.
Drawings
FIG. 1 is a schematic view of the three-dimensional structure of the kit for extracting viral RNA by biomagnetic bead method according to example 1;
FIG. 2 is a sectional view of the kit for extracting viral RNA according to the biomagnetic bead method described in example 1;
FIG. 3 is a sectional view of the kit for extracting viral RNA according to the biomagnetic bead method described in example 2;
fig. 4 is a schematic structural diagram of a chuck in the kit for extracting viral RNA by the biological nano magnetic bead method described in embodiment 2.
Wherein: 1. a box body; 2. a box cover; 3. a reagent chamber; 4. an accommodating chamber; 5. drawing the box; 6. a magnetic plate; 7. a tool box; 8. a reagent storage box; 9. a first reagent bottle; 10. a second reagent bottle; 11. a third reagent bottle; 12. a fourth reagent bottle; 13. a fifth reagent bottle; 14. a sixth reagent bottle; 15. a seventh reagent bottle; 16. magnetic particles; 17. a fixing plate; 18. hanging the plate; 19. a support plate; 20. a bottom case; 21. a base plate; 22. a support plate; 23. a lead screw; 24. an optical axis; 25. clamping a head; 26. a motor; 27. a first mounting hole; 28. a second mounting hole; 29. and (4) mounting the groove.
Detailed Description
The present invention will be described in further detail with reference to the following examples and drawings.
Example 1
As shown in fig. 1 or 2, the embodiment 1 of the present invention provides a kit for extracting viral RNA by using biological nano magnetic bead method, which comprises a box body 1 and a box cover 2 hinged to one side of the box body 1, the box body 1 is internally divided into a reagent chamber 3 and a holding chamber 4 by a transverse plate, the holding chamber 4 is internally provided with a drawing box 5 slidably connected with the box body 1, the drawing box 5 is internally provided with a magnetic device, the reagent chamber 3 is internally provided with a tool box 7 and a reagent storage box 8, the reagent storage box 8 is located at the bottom of the tool box 7, the reagent storage box 8 is internally provided with a first reagent bottle 9 for containing freeze-dried biological nano magnetic bead reagent, a second reagent bottle 10 for containing freeze-dried reagent dilution buffer, a third reagent bottle 11 for containing lysis buffer, a fourth reagent bottle 12 for containing RNA nucleic acid extraction enhancement reagent, and a fifth reagent bottle 13 for containing washing buffer I, A sixth reagent bottle 14 for containing washing buffer solution II and a seventh reagent bottle 15 for containing DNase/RNase-Free elution buffer solution.
The magnetic device can be a magnet or a magnetic substance, and can be used for adsorbing magnetic beads, so that the extraction efficiency of the virus RNA is effectively improved.
Preferably, the magnetic device comprises a magnetic plate 6 made of a magnetic material, the magnetic plate 6 is transversely arranged in the drawer 5, magnetic particles 16 are filled in the drawer 5 at the bottom of the magnetic plate 6, and test tube holes are uniformly formed in the magnetic plate 6.
During the experiment, the test tube is pegged graft in the test tube hole, and 16 agent magnetic sheet 6 homoenergetic of magnetic particle can be used for adsorbing the magnetic bead, effectively improves extraction efficiency, shortens test time, labour saving and time saving more, and the practicality is strong.
Example 2
The embodiment 2 of the utility model provides a structure of kit has further been injectd on embodiment 1's basis, has effectively improved the multi-functionalization of kit to make the kit use simpler, it is more convenient to operate.
As shown in FIG. 3, fixing plates 17 are symmetrically arranged on two sides of the inner top of the reagent chamber 3, hanging plates 18 are connected to the tops of two sides of the tool box 7, and the hanging plates 18 are lapped on the edges of the fixing plates 17. The tool box 7 is lapped on the fixing plate 17 and can be conveniently taken out, and after the tool box 7 is taken out, the reagent bottle can be conveniently taken out.
It should be noted that a support plate 19 is transversely arranged in the tool box 7, the support plate 19 is uniformly provided with insertion holes for inserting test tubes, a bottom box 20 is arranged at the bottom of the support plate 19, and a protective pad is arranged in the bottom box 20.
The jack on the extension board 19 is used for placing the test tube, when experimental operation, can be used for supporting the test tube, and the protection is filled up and can be protected the test tube bottom, effectively plays the effect of anticollision, prevents that the test tube bottom from being cracked the emergence of the circumstances such as.
As shown in fig. 3, in order to improve the intelligence of the reagent kit and save the reagent storage more effort, in the present technical solution, a lifting mechanism for lifting the reagent storage box 8 is further defined in the reagent chamber 3, the lifting mechanism includes lifting components symmetrically arranged at two sides in the reagent chamber 3, a bottom plate 21 transversely arranged at the bottom of the reagent chamber 3, and a support plate 22 transversely arranged between the two lifting components, and the reagent storage box 8 is placed on the support plate 22; the backup pad 22 can be held up to the lifting component that the symmetry set up, because reagent storage box places in backup pad 22, for this reason, reagent storage box can be with being mentioned or put down through lifting component, the more convenient reagent bottle of taking.
As shown in fig. 3, the lifting assembly includes a screw 23, an optical axis 24, a chuck 25 and a motor 26, the top end of the screw 23 is pivotally connected to the fixing plate 17 through a bearing, the bottom end of the screw 23 sequentially passes through the chuck 25 and the bottom plate 21 to be connected to an output shaft of the motor 26, the chuck 25 is in threaded connection with the screw 23, the top end of the optical axis 24 is fixed to the fixing plate 17, and the bottom end of the optical axis 24 passes through the chuck 25 and is fixed to the bottom plate 21; the lead screw 23 with dop 25 threaded connection, when the lead screw 23 rotated under the drive of motor 26, dop 25 rotated along with lead screw 23, but because optical axis 24 carries out circumferencial direction spacing to dop 25, so dop 25 only can follow lead screw 23 up-and-down motion, and then realized promoting.
The two ends of the supporting plate 22 are respectively fixed on the clamping heads 25 of the two lifting assemblies.
As shown in fig. 4, in the present technical solution, a structure of the chuck 25 is further defined, a first mounting hole 27 for passing through the lead screw 23 and a second mounting hole 28 for passing through the optical axis 24 are longitudinally formed in the chuck 25, a thread adapted to the lead screw 23 is arranged in the first mounting hole 27, and the optical axis 24 passes through the second mounting hole 28 and is used for limiting the chuck 25 to move axially along the lead screw 23. Lead screw 23 passes first mounting hole 27 and with first mounting hole 27 threaded connection, and optical axis 24 passes second mounting hole 28, and when lead screw 23 rotated, because optical axis 24 restricted dop 25's circular motion, so dop 25 can only follow optical axis 24 and lead screw 23 up-and-down motion to realized promoting and falling reagent storage box, effectively conveniently take, put the reagent bottle, improved test efficiency.
As shown in fig. 4, preferably, a mounting groove 29 for clamping the support plate 22 is transversely formed on one side of the chuck 25 close to the support plate 22. Mounting groove 29 can be used for the joint backup pad 22's both ends, and for this reason, when dop 25 moved up and down along optical axis 24 and lead screw 23, dop 25 drove backup pad 22 and moved up and down to realize reagent storage box up-and-down motion on backup pad 22, conveniently take out the reagent bottle.
The present invention is not limited to the above-mentioned preferred embodiments, and any other products in various forms can be obtained by the teaching of the present invention, but any changes in the shape or structure thereof, which have the same or similar technical solutions as the present invention, fall within the protection scope of the present invention.
Claims (6)
1. The utility model provides a biological nanometer magnetic bead method draws virus RNA kit, including box body (1) and with box body (1) one side articulated lid (2), its characterized in that, separate for reagent chamber (3) and hold chamber (4) through the diaphragm in box body (1), hold be equipped with in chamber (4) with box body (1) sliding connection's drawing box (5), be equipped with magnetic means in drawing box (5), be equipped with tool holder (7) and reagent case (8) in reagent chamber (3), reagent case (8) are located tool holder (7) bottom, place first reagent bottle (9) that are used for holding freeze-dried biological nanometer magnetic bead reagent in reagent case (8) respectively, be used for holding second reagent bottle (10) of freeze-dried reagent dilution buffer solution, be used for holding third reagent bottle (11) of schizolysis buffer solution, A fourth reagent bottle (12) for containing RNA nucleic acid extraction enhancing reagent, a fifth reagent bottle (13) for containing washing buffer solution I, a sixth reagent bottle (14) for containing washing buffer solution II and a seventh reagent bottle (15) for containing DNase/RNase-Free elution buffer solution;
the magnetic device comprises a magnetic plate (6) made of a magnetic material, the magnetic plate (6) is transversely arranged in the drawer box (5), magnetic particles (16) are filled at the bottom of the magnetic plate (6) in the drawer box (5), and test tube holes are uniformly formed in the magnetic plate (6).
2. The kit for extracting viral RNA according to claim 1, wherein fixing plates (17) are symmetrically arranged on two sides of the top of the reagent chamber (3), hanging plates (18) are connected to the tops of two sides of the tool box (7), and the hanging plates (18) are lapped on the edges of the fixing plates (17).
3. The kit for extracting viral RNA according to claim 2, wherein a support plate (19) is transversely arranged in the tool box (7), the support plate (19) is uniformly provided with jacks for inserting test tubes, a bottom box (20) is arranged at the bottom of the support plate (19), and a protective pad is arranged in the bottom box (20).
4. The kit for extracting viral RNA according to claim 2, wherein the reagent chamber (3) is further provided with a lifting mechanism for lifting the reagent storage box (8), the lifting mechanism comprises lifting components symmetrically arranged at two sides in the reagent chamber (3), a bottom plate (21) transversely arranged at the bottom of the reagent chamber (3) and a support plate (22) transversely arranged between the two lifting components, and the reagent storage box (8) is placed on the support plate (22); wherein,
the lifting assembly comprises a lead screw (23), an optical axis (24), a clamping head (25) and a motor (26), the top end of the lead screw (23) is in pivot connection with the fixing plate (17) through a bearing, the bottom end of the lead screw (23) sequentially penetrates through the clamping head (25) and the bottom plate (21) to be connected with an output shaft of the motor (26), the clamping head (25) is in threaded connection with the lead screw (23), the top end of the optical axis (24) is fixed on the fixing plate (17), and the bottom end of the optical axis (24) penetrates through the clamping head (25) to be fixed on the bottom plate (21);
two ends of the supporting plate (22) are respectively fixed on the clamping heads (25) of the two lifting components.
5. The kit for extracting viral RNA according to claim 4, wherein the chuck (25) is longitudinally provided with a first mounting hole (27) for penetrating the lead screw (23) and a second mounting hole (28) for penetrating the optical axis (24), the first mounting hole (27) is internally provided with a thread adapted to the lead screw (23), and the optical axis (24) passes through the second mounting hole (28) and is used for limiting the axial movement of the chuck (25) along the lead screw (23).
6. The kit for extracting viral RNA according to claim 5, wherein an installation groove (29) for clamping the support plate (22) is transversely formed on one side of the chuck (25) close to the support plate (22).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621121301.0U CN206089660U (en) | 2016-10-13 | 2016-10-13 | Biological nanometer paramagnetic particle method draws viral RNA kit |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621121301.0U CN206089660U (en) | 2016-10-13 | 2016-10-13 | Biological nanometer paramagnetic particle method draws viral RNA kit |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206089660U true CN206089660U (en) | 2017-04-12 |
Family
ID=58483116
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201621121301.0U Active CN206089660U (en) | 2016-10-13 | 2016-10-13 | Biological nanometer paramagnetic particle method draws viral RNA kit |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN206089660U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108587865A (en) * | 2018-05-16 | 2018-09-28 | 曹怡珺 | A kind of magnetic bionanoparticles method extraction serum-virus nucleic acid reagent box |
-
2016
- 2016-10-13 CN CN201621121301.0U patent/CN206089660U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108587865A (en) * | 2018-05-16 | 2018-09-28 | 曹怡珺 | A kind of magnetic bionanoparticles method extraction serum-virus nucleic acid reagent box |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN206089661U (en) | Biological nanometer paramagnetic particle method extracts serum virus RNA kit | |
| CN206089659U (en) | Biological nanometer paramagnetic particle method draws viral DNA kit | |
| CN207330915U (en) | A kind of magnetic bionanoparticles method extracts paraffin-embedded tissue miRNA kits | |
| HK1085010A1 (en) | Latex reagent for adiponectin analysis and method of adiponectin analysis | |
| CN206089660U (en) | Biological nanometer paramagnetic particle method draws viral RNA kit | |
| CN111621416A (en) | Biological magnetic separation method based on mobile magnetic net | |
| CN206089658U (en) | Biological nanometer paramagnetic particle method extracts serum virus DNA kit | |
| CN104479993A (en) | Nucleic acid extraction device for nucleic acid extractor | |
| CN208684984U (en) | A kind of magnetic bionanoparticles kit | |
| CN207623112U (en) | A kind of stirring sampling apparatus of Urine Analyzer | |
| CN201020402Y (en) | Detachable utility type magnetic separating rack | |
| CN204325346U (en) | A kind of instrument for extracting nucleic acid volley of rifle fire device | |
| CN204325348U (en) | A kind of instrument for extracting nucleic acid nucleic acid-extracting apparatus | |
| CN108315243A (en) | Automate sample adding system | |
| CN206375924U (en) | Nucleic acid purification magnetic frame | |
| CN203493772U (en) | Biomechanics experimental clamp | |
| CN207351784U (en) | A kind of 96 orifice plate magnetic bases | |
| CN208964947U (en) | A kind of full-automatic nucleic acid extraction purifying instrument | |
| CN207330916U (en) | A kind of magnetic bionanoparticles method extracts free serum miRNA kits | |
| CN205917253U (en) | Nucleic acid extraction device for nucleic acid extractor | |
| CN219898114U (en) | Anhydrous reaction preparation facilities of chemical reagent | |
| CN206089643U (en) | Biological nanometer paramagnetic particle method draws biological total RNA kit of general type | |
| CN206033738U (en) | Biological nanometer paramagnetic particle method draws general type biological gene DNA of group kit | |
| CN107228943B (en) | The method for measuring bacterial content in fluid sample | |
| CN216445375U (en) | Kit for extracting Chinese herbal medicine genome DNA by biological nano-magnetic bead method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20180417 Address after: 100096 room 916, King Yan Long building, Hui lung Guan Town, Changping District, Beijing. Patentee after: Beijing nine Lianhua Culture Communication Co., Ltd. Address before: 100098 Beijing city Haidian District Dazhongsi No. 13 Building No. 1 hospital basement A02-28 Patentee before: The state of Beijing Rongzhi Biological Technology Co. Ltd. |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20210329 Address after: 102200 1101, building 3, No.1 a, Chaoqian Road, science and Technology Park, Changping District, Beijing Patentee after: Beijing Jinyuan Liheng Biotechnology Co.,Ltd. Address before: 100096 room 916, King Yan Long building, Hui lung Guan Town, Changping District, Beijing. Patentee before: Beijing nine Lianhua Culture Communication Co.,Ltd. |