CN206252559U - Experimental rat sacculus irrigation stomach device - Google Patents
Experimental rat sacculus irrigation stomach device Download PDFInfo
- Publication number
- CN206252559U CN206252559U CN201620714546.8U CN201620714546U CN206252559U CN 206252559 U CN206252559 U CN 206252559U CN 201620714546 U CN201620714546 U CN 201620714546U CN 206252559 U CN206252559 U CN 206252559U
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- China
- Prior art keywords
- sacculus
- gavage
- bendable
- cylinder
- irrigation stomach
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Abstract
The utility model discloses a kind of experimental rat sacculus irrigation stomach device, including gavage cylinder, sacculus and bendable gastric perfusion needle, the gavage cylinder has head end and tail end；The sacculus has an opening, and the opening connects with the tail end sealing of gavage cylinder；The bendable gastric perfusion needle includes leading portion, stage casing and back segment, and back segment is connected with the head end of gavage cylinder, and intersegmental with angle per adjacent two；The head end of the bendable gastric perfusion needle is provided with protection bulb, and its surface is provided with multiple drug row holes, and inside is provided with multiple medicine-pouring holes connected with the drug row hole.The part such as throat, oesophagus, stomach, the lungs of experimenter to rat in administration process can be reduced by the utility model cause mechanical injuries, improve the efficiency of gastric infusion, the death rate of rat can also be reduced simultaneously, be conducive to smoothly completing for interior animal experiment.
Description
Technical field
The utility model is related to a kind of doctor, pharmacy teaching and scientific experiment apparatus, more particularly to a kind of experimental rat to use
Sacculus irrigation stomach device.
Background technology
Zoopery is the basic skills of the experimental studies such as physiology, immunology, toxicology, pharmacodynamics and pharmacology, root
According to the height of the purpose of experimental study, the strain of experimental animal and Experimental agents dosage, experimenter requires dynamic to experiment
Thing takes different administering modes, such as gastric infusion, intracerebroventricular, tail vein injection, intraperitoneal injection, intramuscular injection etc..Its
In, direct oral cavity gastric infusion is one of most common zoopery administering mode, and gastric infusion contributes to a large amount of oral class medicine things
Pharmacology, pharmacodynamics and toxicologic study, especially many motherland's medicine compound preparations or simple are mostly to be prepared into water
Decoction, pill, powder and granule etc., carry out motherland's medicine prescription or simple grinds to the science of experimental animal model
Study carefully, gastric infusion is often most common zoopery administering mode.
Experimenter carries out gavage to rat, and the conventional irrigation stomach device for using is mostly metal gastric perfusion needle, the matter of metal gastric perfusion needle
Ground is hard, and pliability is poor, and it is relatively thin compared with the mucous layer of thin and oesophagus, muscle layer, tunica fibrosa to add the oesophagus of rat, therefore is giving
When rat carries out gavage, it is easy to cause the physical damnification of rat esophagus, or even oral cavity, throat and stomach can also be caused beautifully adorned
The physical damnification of door sphincter etc., so as to influence the process and effect of rat experiment, therefore explores that design is a kind of safely, has
Effect, quick irrigation stomach device are particularly important.
The content of the invention
In order to solve the problems, such as existing irrigation stomach device, the utility model provides a kind of new experimental rat and is filled with sacculus
Stomach device, can greatly reduce experimenter's irrigation stomach device in administration process and the positions such as rat throat, oesophagus, stomach, lungs are made
Into mechanical injuries.
It is the experimental rat of the present utility model sacculus irrigation stomach device up to above-mentioned purpose, including gavage cylinder, sacculus and bendable
Gastric perfusion needle, the gavage cylinder has head end and tail end；The sacculus has an opening, and the opening is close with the tail end of gavage cylinder
Envelope connection；The bendable gastric perfusion needle includes leading portion, stage casing and back segment, and back segment is connected with the head end of gavage cylinder, and often
Adjacent two is intersegmental with angle；The head end of the bendable gastric perfusion needle is provided with protection bulb, and its surface is provided with multiple drug row holes, interior
Portion is provided with multiple medicine-pouring holes connected with the drug row hole.
Preferably, the sacculus outer surface is provided with amplitude ripple line.
Preferably, the sacculus outlet is sealed with the junction of gavage cylinder tail end by sealed ubber strip.
Preferably, the gavage cylinder is marked with the graduation indication line for representing volume.
Preferably, the length ratio of the bendable gastric perfusion needle leading portion, stage casing and back segment is 1:1:1.
Preferably, the bendable gastric perfusion needle leading portion is 160 degree with the pin bent angle in stage casing, stage casing is with the bending angle of back segment
120 degree.
Preferably, the protection bulb is elliposoidal.
Preferably, the protection bulb is provided with 1~10 group of drug row hole and medicine-pouring hole.
Preferably, the protection bulb is provided with 9 groups of drug row holes and medicine-pouring hole, wherein 1 group faces the bendable gavage
The head end of pin.
Preferably, the bendable gastric perfusion needle is marked with depth instruction line.
The utility model difference from prior art is that the utility model achieves following technique effect：Can reduce
Mechanical injuries are caused in the part such as throat, oesophagus, stomach, the lungs of experimenter in administration process to rat, improve gavage
The efficiency of administration, while the death rate of rat can also be reduced, is conducive to smoothly completing for interior animal experiment.
The utility model is described in further detail below in conjunction with the accompanying drawings.
Brief description of the drawings
Fig. 1 is the structural representation of experimental rat sacculus irrigation stomach device in the embodiment of the utility model one；
Fig. 2 is the structural representation of protection bulb in the embodiment of the utility model one.
Description of reference numerals：
10- gavages cylinder；11- head ends；12- tail ends；
20- sacculus；
30- bendable gastric perfusion needles；31- leading portions；32- stage casings；33- back segments；
The sealed ubber strips of 41- first；The sealed ubber strips of 42- second；
50- closures；60- protects bulb；601- drug rows hole；602- medicine-pouring holes.
Specific embodiment
With reference to embodiments, technical characteristic above-mentioned to the utility model and other and advantage are made in more detail
It is bright.
As depicted in figs. 1 and 2, experimental rat of the present utility model sacculus irrigation stomach device, including gavage cylinder 10, sacculus 20,
Folding gastric perfusion needle 30.
Gavage cylinder 10 has head end 11 and tail end 12.Gavage cylinder is marked with the graduation indication line for representing volume, is conducive to reality
The personnel of testing are accurately determined the dosage to rat oral gavage administration, it is to avoid the gastral cavity of rat is oppressed because dosage is excessive, causes it
Have a stomach upset sense, in addition it is dead.In one embodiment, gavage cylinder directly using removal syringe needle and the syringe of propeller, hold by maximum
Product is 2.0mL, and 0.08mL is represented per small lattice.
Sacculus 20 is the cystic structures of similar spindle, and its operability, practicality are stronger, are easy to experimenter to carry out gavage
Dosing techniques.
Sacculus 20 has an opening, in the insertion opening of tail end 12 of gavage cylinder, and is carried out with the first sealed ubber strip 41 close
Envelope.In addition, in this embodiment, the other end of sacculus is additionally provided with another opening, and with the sealed ubber strip 42 of closure 50 and second
Sealed.
The outer surface of sacculus 20 is provided with amplitude ripple line, is conducive to experimenter to primarily determine that lower absorption liquid substantially
Amount.
Bendable gastric perfusion needle 30 includes leading portion 31, stage casing 32 and back segment 33, and back segment 33 is connected with the head end of gavage cylinder, and
It is intersegmental with angle per adjacent two.
In one embodiment, before bendable gastric perfusion needle 30, in and back segment length ratio be 1:1:1.In one embodiment, preceding,
In and the length of back segment be 3cm.
In one embodiment, the leading portion 31 of bendable gastric perfusion needle 30 and the bending angle α in stage casing 32 are 160 degree, stage casing and back segment
Bending angle beta be 120 degree.
Three sections of bendables of gastric perfusion needle are designed with the basic shape that rat in administration process is preferably observed beneficial to experimenter
State, while this design can reduce irrigation stomach device being blocked to the sight line of experimenter, promotes experimenter quickly and accurately to find
To the throat and UE of rat, so as to improve the gavage efficiency of rat.
The head end of bendable gastric perfusion needle 30 is provided with protection bulb 60, and its surface is provided with multiple drug row holes 601, and inside is provided with many
The individual medicine-pouring hole 602 connected with drug row hole 601.
In one embodiment, protection bulb 60 is elliposoidal, which is provided with 1~10 group of drug row hole and medicine-pouring hole, more preferably, if
There are 9 groups, wherein 1 group of head end for facing bendable gastric perfusion needle 30.
Protection bulb can greatly reduce experimenter in rat oral gavage administration process to the damage of rat UGI
Wound, reduces stimulation of the medicine to rat esophagus mucous membrane and gastral cavity mucous membrane, and experimenter is to rat institute during mitigating gastric infusion
Pain or sense of discomfort for causing etc..
In one embodiment, the outer surface of gastric perfusion needle is provided with depth instruction line, it is possible thereby to determine that gastric perfusion needle enters rat stomach
The administration scale in chamber, this number of division value is recorded as reference, is easy to next rat oral gavage to be administered, and reduces gastric infusion
Time for groping and it is also prevented from lungs, diaphram, intestinal tube of irrigation stomach device insertion rat etc., it is to avoid internal organs damage occurs in rat
Wound.
The utility model experimental rat is as follows with the use flow of sacculus irrigation stomach device：
1. experimenter's right hand suitably unclamps sacculus 20, and the gas pressure reduction in sacculus 20, sacculus irrigation stomach device draws 2ml
Gavage medicine, gavage medicine by drug row hole 601, medicine-pouring hole 602, bendable gastric perfusion needle 30, into gavage cylinder 10；
3. experimenter's right hand clutches sacculus 20, while observing the amplitude ripple line on the basic status of rat, sacculus, filling
Stomach cylinder volume scale value and gastric perfusion needle deep calibration value, experimenter can slowly, precisely controllable process be filled by gavage medicine
Stomach cylinder 10, bendable gastric perfusion needle 30, medicine-pouring hole 602, drug row hole 601 are slowly flowed out, and into the gastral cavity of rat, complete this filling
Stomach is administered.
Embodiment described above is only that preferred embodiment of the present utility model is described, not to this practicality
New scope is defined, and on the premise of the utility model design spirit is not departed from, those of ordinary skill in the art are to this
Various modifications and improvement that the technical scheme of utility model is made, all should fall into the protection of the utility model claims determination
In the range of.
Claims (10)
1. a kind of experimental rat sacculus irrigation stomach device, it is characterised in that including：
Gavage cylinder, with head end and tail end；
Sacculus, with an opening, the opening connects with the tail end sealing of gavage cylinder；
Bendable gastric perfusion needle, including leading portion, stage casing and back segment, back segment are connected with the head end of gavage cylinder, and per adjacent two
It is intersegmental with angle；The head end of the bendable gastric perfusion needle is provided with protection bulb, and its surface is provided with multiple drug row holes, and inside is provided with
Multiple medicine-pouring holes connected with the drug row hole.
2. experimental rat as claimed in claim 1 sacculus irrigation stomach device, it is characterised in that the sacculus outer surface is provided with amplitude
Wave molding.
3. experimental rat as claimed in claim 1 sacculus irrigation stomach device, it is characterised in that the sacculus outlet and the gavage
The junction of cylinder tail end is sealed by sealed ubber strip.
4. experimental rat as claimed in claim 1 sacculus irrigation stomach device, it is characterised in that the gavage cylinder is marked with expression to be held
Long-pending graduation indication line.
5. experimental rat as claimed in claim 1 sacculus irrigation stomach device, it is characterised in that the bendable gastric perfusion needle leading portion, in
The length ratio of section and back segment is 1:1:1.
6. the sacculus irrigation stomach device of the experimental rat as described in claim 1 or 5, it is characterised in that the bendable gastric perfusion needle leading portion
It it is 160 degree with the pin bent angle in stage casing, stage casing is 120 degree with the bending angle of back segment.
7. experimental rat as claimed in claim 1 sacculus irrigation stomach device, it is characterised in that the protection bulb is elliposoidal.
8. experimental rat as claimed in claim 1 sacculus irrigation stomach device, it is characterised in that the protection bulb is provided with 1~10
Group drug row hole and medicine-pouring hole.
9. experimental rat as claimed in claim 8 sacculus irrigation stomach device, it is characterised in that the protection bulb is provided with 9 groups of drug rows
Hole and medicine-pouring hole, wherein 1 group of head end for facing the bendable gastric perfusion needle.
10. experimental rat as claimed in claim 1 sacculus irrigation stomach device, it is characterised in that the bendable gastric perfusion needle is marked with
Depth instruction line.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620714546.8U CN206252559U (en) | 2016-07-07 | 2016-07-07 | Experimental rat sacculus irrigation stomach device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620714546.8U CN206252559U (en) | 2016-07-07 | 2016-07-07 | Experimental rat sacculus irrigation stomach device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206252559U true CN206252559U (en) | 2017-06-16 |
Family
ID=59022236
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201620714546.8U Expired - Fee Related CN206252559U (en) | 2016-07-07 | 2016-07-07 | Experimental rat sacculus irrigation stomach device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN206252559U (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107897029A (en) * | 2018-01-08 | 2018-04-13 | 上海犊瑞乳品设备有限公司 | Calf feeding device |
| CN108703821A (en) * | 2018-05-28 | 2018-10-26 | 中国医学科学院医学实验动物研究所 | A kind of gastric perfusion needle and preparation method thereof of the sterile rats and mice cub artificial suckling of different days |
| CN109549748A (en) * | 2017-09-26 | 2019-04-02 | 容县科学实验研究所 | A kind of dedicated continuous drencher of animal and veterinary |
| CN110420072A (en) * | 2019-07-24 | 2019-11-08 | 莆田学院 | A kind of rat oral gavage device applied to ergology |
-
2016
- 2016-07-07 CN CN201620714546.8U patent/CN206252559U/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109549748A (en) * | 2017-09-26 | 2019-04-02 | 容县科学实验研究所 | A kind of dedicated continuous drencher of animal and veterinary |
| CN107897029A (en) * | 2018-01-08 | 2018-04-13 | 上海犊瑞乳品设备有限公司 | Calf feeding device |
| CN108703821A (en) * | 2018-05-28 | 2018-10-26 | 中国医学科学院医学实验动物研究所 | A kind of gastric perfusion needle and preparation method thereof of the sterile rats and mice cub artificial suckling of different days |
| CN110420072A (en) * | 2019-07-24 | 2019-11-08 | 莆田学院 | A kind of rat oral gavage device applied to ergology |
| CN110420072B (en) * | 2019-07-24 | 2024-01-23 | 莆田学院 | Be applied to functional rat lavage device |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20170616 Termination date: 20190707 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |