CN206007399U - Experimental rat irrigation stomach device - Google Patents

Experimental rat irrigation stomach device Download PDF

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Publication number
CN206007399U
CN206007399U CN201620713860.4U CN201620713860U CN206007399U CN 206007399 U CN206007399 U CN 206007399U CN 201620713860 U CN201620713860 U CN 201620713860U CN 206007399 U CN206007399 U CN 206007399U
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CN
China
Prior art keywords
gavage
cylinder
experimental rat
irrigation stomach
stomach device
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Expired - Fee Related
Application number
CN201620713860.4U
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Chinese (zh)
Inventor
刘得水
费洪新
张晓杰
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Qiqihar Medical University
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Qiqihar Medical University
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Priority to CN201620713860.4U priority Critical patent/CN206007399U/en
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Publication of CN206007399U publication Critical patent/CN206007399U/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Abstract

The utility model discloses a kind of experimental rat irrigation stomach device, including gavage cylinder, gear and bendable gastric perfusion needle, the gavage cylinder has head end and tail end, piston handle is provided with the gavage cylinder, and the cross section of the piston handle is square, its one end for going deep into the gavage cylinder is provided with piston, and the one side of the piston handle is provided with tooth bar;Tail end of the gear located at the gavage cylinder, the gear can with the piston handle on the mutual accurate bite of tooth bar, rotate the gear and can drive the piston handle movement;The bendable gastric perfusion needle includes that leading portion, stage casing, back segment and latter end, latter end are connected with the head end of the gavage cylinder, and intersegmental with angle per adjacent two;The head end of the gastric perfusion needle is provided with protection bulb, and its surface is provided with multiple drug row collar extensions, and inside is provided with multiple drug row internal orifices connected with the drug row collar extension.

Description

Experimental rat irrigation stomach device
Technical field
The utility model is related to a kind of doctor, pharmacy teaching and scientific experiment apparatus, and more particularly to a kind of experimental rat is used Irrigation stomach device.
Background technology
Experimental rat is the animal varieties that commonly uses in basic medical research, and the conventional administering mode of the kind rat includes filling Stomach administration, lumbar injection, tail vein injection, hypodermic injection etc., wherein gastric infusion are the conventional administering modes of experimental rat One of.In clinic study, mostly the administering mode of compound preparation or simple water decoction is to be administered orally through patient, Medicinal substances extract in combination with motherland's medicine is to be prepared into water decoction to be administered mostly, then in animal experiment study, The administering mode of compound preparation or simple water decoction is also required to be administered through the oral cavity of animal.Therefore, explore new Experimental rat irrigation stomach device, by carrying out gastric infusion through experimental rat oral cavity, carries out motherland's medicine compound preparation or single The experimental study of the extract for preventing and treating disease animal model of medicine is just particularly important.
At present, experimenter carries out gavage to experimental rat, the conventional irrigation stomach device for using pharynx often to experimental rat Cause physical damnification in the positions such as larynx, oesophagus, stomach orifice of the stomach, diaphram, intestinal tube.
Content of the invention
The positions such as the throat of experimental rat, oesophagus, stomach orifice of the stomach, diaphram, intestinal tube can be caused to solve existing irrigation stomach device Physically impaired problem, the utility model provide a kind of new irrigation stomach device.
It is the experimental rat irrigation stomach device of the present utility model up to above-mentioned purpose, including gavage cylinder, gear and bendable gavage Pin, the gavage cylinder have head end and tail end, be provided with piston handle, and the cross section of the piston handle is in side in the gavage cylinder Shape, its one end for going deep into the gavage cylinder are provided with piston, and the one side of the piston handle is provided with the jagged tooth bar of a row;Institute State tail end of the gear located at the gavage cylinder, the gear can with the piston handle on the mutual accurate bite of tooth bar, rotate institute State gear and can drive the piston handle movement;The bendable gastric perfusion needle includes leading portion, stage casing, back segment and latter end, latter end and institute The head end for stating gavage cylinder is connected, and intersegmental with angle per adjacent two;The head end of the gastric perfusion needle is provided with protection bulb, its table Face is provided with multiple drug row collar extensions, and inside is provided with multiple drug row internal orifices connected with the drug row collar extension.
Preferably, before, during and after the bendable gastric perfusion needle and latter end length ratio be 1:1:1:1、2:1:1:1、1:2:1: 1 or 1:1:2:1.
Preferably, the gastric perfusion needle leading portion is 160 degree with the angle in stage casing, stage casing is 140 degree with the angle of back segment, back segment Angle with latter end is 170 degree.
Preferably, the bendable gastric perfusion needle is made up of polypropylene material, can reduce to experimental rat oral cavity, throat, food The physical damnification that pipe and stomach cardiac sphincter etc. are caused.
Preferably, being marked with the graduation indication line for representing volume on the gavage cylinder.More preferably, the maximum of the gavage cylinder Capacity is 2mL, represents 0.04mL per little lattice.
Preferably, the gear is connected with the tail end of the gavage cylinder by a fixed support.
Preferably, the protection bulb is elliposoidal.
Preferably, the protection bulb is provided with 7 groups of drug row collar extensions and drug row internal orifice altogether, wherein 1 group faces the gavage The head end of pin.
The utility model difference from prior art is that the utility model achieves following technique effect:
(1) square piston handle one end of experimental rat irrigation stomach device has piston to go deep in irrigation stomach device cylinder, and the one of square piston handle Side have rack and pinion closely, accurate bite, so design and can ensure that experimenter is controllably filled to experimental rat Stomach is administered, and is conducive to experimenter's speed that reasonably Control release rat oral gavage is administered, so as to improve experimenter to experiment The efficiency of rat oral gavage administration;
(2) gavage drum outer wall sets graduation indication line, it is ensured that experimenter accurately carries out gastric infusion to experimental rat, Error of the experimenter to experimental rat gastric infusion can be reduced with this, it can also be ensured that in appropriate amount experimental rat is filled Stomach be administered, it is to avoid gastric infusion dosage excessive and oppress experimental rat gastral cavity and oesophagus bottom, design gavage cylinder graduation indication Line is conducive to being smoothed out for experimental rat gastric infusion;
(3) gastric perfusion needle is divided into four parts, including leading portion, stage casing, back segment, latter end, the ratio most preferably 1 of each segment length:1: 1:1.Each section of the gastric perfusion needle of experimental rat irrigation stomach device is bent into different angles respectively, and these are designed with beneficial to experimenter at any time The basic status of observation experiment rat, it is to avoid irrigation stomach device is blocked to the sight line of experimenter, is conducive to experimenter quick, accurate Search out the throat entrance of experimental rat, while design multiple bending angle α, β, γ of gastric perfusion needle, and bending angle α, β, γ more relaxes, and advantageously reduces physical damnification of the gastric perfusion needle to experimental rat Esophageal Mucosa, gastral cavity mucous membrane etc., and then improves Quality of the experimenter to experimental rat gastric infusion;
(4) gavage needle end is provided with protection bulb, and protects bulb to be preferably elliposoidal, and preferably has 6 groups of drug row internal orifices The periphery of protection bulb is located at drug row collar extension, and 1 group of drug row internal orifice and drug row collar extension face the head end of gastric perfusion needle, furthermore, fill Stomach pin outer surface is provided with gastric perfusion needle depth instruction line, and these designs can avoid conventional conventional irrigation stomach device such as metal gastric perfusion needle The drawbacks of, it is to avoid metal needle easily causes the physics to experimental rat oral cavity, throat, oesophagus and stomach cardiac sphincter etc. and damages The problem of wound, reduces stimulation of the medicine to experimental rat Esophageal Mucosa and stomach transmucosal etc., is greatly enhanced experimental rat filling The efficiency of stomach administration.
The utility model is described in further detail below in conjunction with the accompanying drawings.
Description of the drawings
Fig. 1 is the structural representation of experimental rat irrigation stomach device in one embodiment of the utility model;
Fig. 2 is the structural representation for protecting bulb in one embodiment of the utility model.
Description of reference numerals:
10- gavage cylinders;11- head ends;12- tail ends;101- piston handles;102- pistons;103- tooth bars;
20- gears;21- fixed supports;
30- bendable gastric perfusion needles;31- leading portions;32- stage casings;33- back segments;34- latter ends;35- protects bulb;351- drug rows Collar extension;352- drug row internal orifices;36- depth instruction lines.
Specific embodiment
With reference to embodiments, the above-mentioned He other technical characteristic of the utility model and advantage are made in more detail Bright.
As depicted in figs. 1 and 2, experimental rat irrigation stomach device of the present utility model, including gavage cylinder 10, gear 20 and bending Formula gastric perfusion needle 30.
Gavage cylinder 10 has head end 11 and tail end 12, is provided with piston handle 101, and the cross section of piston handle is side in gavage cylinder Shape, its one end for going deep into gavage cylinder are provided with piston 102, and the one side of piston handle 101 is provided with the jagged tooth bar 103 of a row. Preferably, for ease of drawing the liquid of certain volume and ensureing accurate administration, being marked with gavage cylinder and representing that the scale of volume refers to Timberline.In this embodiment, the maximum capacity of gavage cylinder is 2mL, represents 0.04mL per little lattice.
Gear 20 by a fixed support 21 at the tail end 12 of gavage cylinder, gear 20 can with piston handle on tooth bar 103 mutual accurate bites, can drive pinion rotation when promoting piston handle.
Bendable gastric perfusion needle 30 includes the head end 11 of leading portion 31, stage casing 32, back segment 33 and latter end 34, latter end 34 and gavage cylinder It is connected, and the intersegmental angle α with of leading portion is 160 degree, stage casing is 140 degree with the angle β of back segment, and the folder of back segment and latter end Angle γ is 170 degree, in addition, each segment length ratio is 1:1:1:1, in other embodiments, before, during and after bendable gastric perfusion needle and The length ratio of latter end can also be 2:1:1:1、1:2:1:1 or 1:1:2:1.For reducing damage of the gastric perfusion needle to experimental rat as far as possible Wound, in this embodiment, gastric perfusion needle selects to adopt polypropylene material.
The outer surface of gastric perfusion needle 30 has depth instruction line 36.
In addition, the head end of gastric perfusion needle is provided with elliposoidal protection bulb 35, its surface is provided with 7 drug row collar extensions 351, and inside sets There are 7 drug row internal orifices 352 connected with drug row collar extension, wherein 1 group drug row collar extension to face the head of gastric perfusion needle 30 with drug row internal orifice End.Medicine finally enters mouse gastral cavity from drug row collar extension.Certainly, in other embodiments, those skilled in the art can be according to reality Border situation selects the drug row hole of other quantity and dosing holes.
Experimental rat of the present utility model is as follows using idiographic flow with irrigation stomach device:
Experimenter's right hand holds irrigation stomach device, and hand thumb dextrorotation rotating disk 20, gear 20 are made square by tooth bar 103 Piston handle 101 is moved to the direction away from gavage cylinder 10, forms vacuum in gavage cylinder 10, reduced pressure, promote gavage liquid from The drug row collar extension 351 of gastric perfusion needle elliposoidal protection bulb 35 enters drug row internal orifice 352, leading portion of the gavage liquid through gastric perfusion needle 30 31st, stage casing 32, back segment 33, latter end 34, enter gavage cylinder 10, and the gavage liquid of 2ml drawn by gavage cylinder 10, big so as to complete experiment Mouse draws 2ml gavage liquid with irrigation stomach device.
Experimenter's right hand captures the rat-tail end of experimental rat, and left hand captures experimental rat using labor protection glove Experimental rat is fixed on experimenter's left hand centre of the palm, the long tail of experimental rat by nape, experimenter's right hand auxiliary left hand It is put in experimenter's left hand little finger of toe.
Experimenter's right hand holds irrigation stomach device, and hand thumb rotate counterclockwise gear 20, gear 20 are made square by tooth bar 103 Piston handle 101 is subject to external force pressure to the direction movement near gavage cylinder 10, the gavage liquid in gavage cylinder 3.Work in external force With under, gavage liquid is through the end 34 of gavage cylinder 10, gastric perfusion needle, back segment 33, stage casing 32, leading portion 31, elliposoidal protection bulb 35 drug row internal orifice 352, drug row collar extension 351, final appropriate gavage liquid enter experimental rat gastral cavity, while observing gastric perfusion needle 30 The gastric perfusion needle depth instruction line 36 entered in experimental rat gastral cavity, is conducive to next experimental rat gastric infusion.These designs The quality and efficiency of experimental rat gastric infusion will be greatly enhanced.
Embodiment described above is only that preferred embodiment of the present utility model is described, not to this practicality New scope is defined, and on the premise of without departing from the utility model design spirit, those of ordinary skill in the art are to this Various modifications and improvement that the technical scheme of utility model is made, all should fall into the protection of the utility model claims determination In the range of.

Claims (10)

1. a kind of experimental rat irrigation stomach device, it is characterised in that include:
Gavage cylinder, with head end and tail end, is provided with piston handle, and the cross section of the piston handle is square in the gavage cylinder, Its one end for going deep into the gavage cylinder is provided with piston, and the one side of the piston handle is provided with the jagged tooth bar of a row;
Gear, located at the tail end of the gavage cylinder, the gear can with the piston handle on the mutual accurate bite of tooth bar, rotate Gear can drive the piston handle movement;And
Bendable gastric perfusion needle, it include that leading portion, stage casing, back segment and latter end, latter end are connected with the head end of the gavage cylinder, and per Adjacent two is intersegmental with angle;The head end of the gastric perfusion needle is provided with protection bulb, and its surface is provided with multiple drug row collar extensions, and inside sets There are multiple drug row internal orifices connected with the drug row collar extension.
2. experimental rat irrigation stomach device as claimed in claim 1, it is characterised in that before, during and after the bendable gastric perfusion needle and The length ratio of latter end is 1:1:1:1、2:1:1:1、1:2:1:1 or 1:1:2:1.
3. experimental rat irrigation stomach device as claimed in claim 1, it is characterised in that the leading portion is 160 with the angle in stage casing Degree, stage casing are 140 degree with the angle of back segment, and back segment is 170 degree with the angle of latter end.
4. experimental rat irrigation stomach device as claimed in claim 1, it is characterised in that the bendable gastric perfusion needle is by polypropylene material Material is made.
5. experimental rat irrigation stomach device as claimed in claim 1, it is characterised in that be marked with expression volume on the gavage cylinder Graduation indication line.
6. experimental rat irrigation stomach device as claimed in claim 5, it is characterised in that the maximum capacity of the gavage cylinder is 2mL, 0.04mL is represented per little lattice.
7. experimental rat irrigation stomach device as claimed in claim 1, it is characterised in that the gear is by a fixed support and institute State the tail end connection of gavage cylinder.
8. experimental rat irrigation stomach device as claimed in claim 1, it is characterised in that the protection bulb is elliposoidal.
9. the experimental rat irrigation stomach device as described in claim 1 or 8, it is characterised in that the protection bulb is provided with 7 groups of rows altogether Medicine collar extension and drug row internal orifice, the wherein 1 group head end for facing the gastric perfusion needle.
10. experimental rat irrigation stomach device as claimed in claim 1, it is characterised in that the gastric perfusion needle is marked with depth instruction Line.
CN201620713860.4U 2016-07-07 2016-07-07 Experimental rat irrigation stomach device Expired - Fee Related CN206007399U (en)

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Application Number Priority Date Filing Date Title
CN201620713860.4U CN206007399U (en) 2016-07-07 2016-07-07 Experimental rat irrigation stomach device

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Application Number Priority Date Filing Date Title
CN201620713860.4U CN206007399U (en) 2016-07-07 2016-07-07 Experimental rat irrigation stomach device

Publications (1)

Publication Number Publication Date
CN206007399U true CN206007399U (en) 2017-03-15

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107389642A (en) * 2017-08-01 2017-11-24 北京科技大学 Unicellular efficient capture, the imaging of high intension and full transcriptome analysis apparatus and method
CN110420072A (en) * 2019-07-24 2019-11-08 莆田学院 A kind of rat oral gavage device applied to ergology

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107389642A (en) * 2017-08-01 2017-11-24 北京科技大学 Unicellular efficient capture, the imaging of high intension and full transcriptome analysis apparatus and method
CN110420072A (en) * 2019-07-24 2019-11-08 莆田学院 A kind of rat oral gavage device applied to ergology
CN110420072B (en) * 2019-07-24 2024-01-23 莆田学院 Be applied to functional rat lavage device

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CF01 Termination of patent right due to non-payment of annual fee
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Granted publication date: 20170315

Termination date: 20190707