CN206007398U - Experiment mice irrigation stomach device - Google Patents
Experiment mice irrigation stomach device Download PDFInfo
- Publication number
- CN206007398U CN206007398U CN201620713847.9U CN201620713847U CN206007398U CN 206007398 U CN206007398 U CN 206007398U CN 201620713847 U CN201620713847 U CN 201620713847U CN 206007398 U CN206007398 U CN 206007398U
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- China
- Prior art keywords
- gavage
- bendable
- cylinder
- perfusion needle
- gastric perfusion
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Abstract
The utility model discloses a kind of experiment mice irrigation stomach device, including gavage cylinder, which has head end and tail end, is provided with piston push rod in gavage cylinder, and its one end for going deep into gavage cylinder is provided with piston, and the one side of piston push rod is provided with the jagged tooth bar of a row；The tail end of the gavage cylinder is provided with one and actively adjusts gear, the mutual accurate bite of the tooth bar actively adjusted on gear and the piston push rod, rotates and actively adjusts gear the piston push rod can be driven to move；The head end of the gavage cylinder is provided with two liquid outlets, is respectively equipped with first and second bendable gastric perfusion needle, and the first bendable gastric perfusion needle has forward and backward two sections, arranges into obtuse angle therebetween；The second bendable gastric perfusion needle have before, during and after three sections, its adjacent two intersegmental into obtuse angle arrange and bending in the same direction；The head end of first and second bendable gastric perfusion needle is equipped with protection bulb, and its surface is provided with multiple drug row collar extensions, and inside is provided with multiple drug row internal orifices connected with the drug row collar extension.
Description
Technical field
The utility model is related to a kind of doctor, pharmacy teaching and scientific experiment apparatus, and more particularly to a kind of experiment mice is used
Irrigation stomach device.
Background technology
Experiment mice is the toy that commonly uses in the basic medical researches such as pharmacology, pharmacodynamics, toxicology, physiology, often
Administering mode includes a lot, such as gastric infusion, tail vein injection, lumbar injection etc., and wherein direct oral cavity gastric infusion is
One of conventional administering mode of mouse.Experimenter carries out the food that gastric infusion needs metal gastric perfusion needle is inserted mouse to mouse
Pipe, and make metal gastric perfusion needle reach mouse gastral cavity, due to the oesophagus of mouse relatively fine and narrow, it is easy to occur gavage mistake
Lose, serious in the case of can also cause the impaired perforation of mouse stomach, diaphram, lung cavity bleeding, intestinal canal damage etc., so as to affect reality
That tested is smoothed out.Therefore, a kind of practical novel experimental mouse irrigation stomach device is explored, by through murine oral, throat, oesophagus
Carry out gastric infusion to be just particularly important.
However, existing irrigation stomach device often causes mechanical injuries to the UGI of mouse, it is impossible to safe, accurate,
Controllable, quickly complete gastric infusion, and cause the quality and efficiency of gastric infusion not high.
Content of the invention
The technical problems to be solved in the utility model is to provide the experiment mice irrigation stomach device of a new structure, is beneficial to reality
Testing personnel controllably, accurately, safely, rapidly to mouse carries out gastric infusion, it is to avoid experimenter causes thing to mouse
Reason is damaged.
It is the experiment mice irrigation stomach device of the present utility model up to above-mentioned purpose, including gavage cylinder, which has head end and tail
End, is provided with piston push rod in the gavage cylinder, and its one end for going deep into the gavage cylinder is provided with piston, and the one of the piston push rod
Side is provided with the jagged tooth bar of a row；Wherein, the tail end of the gavage cylinder is provided with one and actively adjusts gear, and the active is adjusted
The mutual accurate bite of tooth bar on gear and the piston push rod, rotates and actively adjusts gear and can drive the piston push rod shifting
Dynamic；The head end of the gavage cylinder is provided with two liquid outlets, is respectively equipped with first and second bendable gastric perfusion needle, and first folding
Curved formula gastric perfusion needle has forward and backward two sections, arranges into obtuse angle therebetween；The second bendable gastric perfusion needle have before, during and after three sections,
Its adjacent two intersegmental into obtuse angle arrange and bending in the same direction；And, the head end of first and second bendable gastric perfusion needle is equal
Protection bulb is provided with, its surface is provided with multiple drug row collar extensions, inside is provided with multiple drug row internal orifices connected with the drug row collar extension.
Preferably, first and second bendable gastric perfusion needle described is axially arranged along the gavage cylinder.
Preferably, first and second bendable gastric perfusion needle described between the gavage cylinder stack shell have different angles.
Preferably, the angle between the front and rear sections of the first bendable gastric perfusion needle is 120 degree；Second bendable is filled
Before stomach pin, in intersegmental angle be 140 degree, in, the angle between back segment be 160 degree.
Preferably, the length ratio of the first bendable gastric perfusion needle front and rear sections is 5:11, before the second bendable gastric perfusion needle,
In, the length ratio of back segment be 6:7:3.
Preferably, the protection bulb is elliposoidal, and 3 groups of drug row collar extensions and drug row internal orifice is provided with, wherein 1 group faces
The head end of respective bendable gastric perfusion needle.
Preferably, first and second bendable gastric perfusion needle described is marked with depth instruction line.
Preferably, the gavage tube outer surface indicates volume graduation indication line.
Preferably, the gear that actively adjusts is connected with the tail end of the gavage cylinder by a fixed mount, the active is adjusted
Section gear is connected with the fixed mount by a rotating shaft.
First and second bendable gastric perfusion needle described is made up of polypropylene material.
The utility model difference from prior art is that the utility model achieves following technique effect：By this reality
With new, in mouse stomach administration process, be conducive to mechanical injuries of experimenter's minimizing to mouse UGI, with
This reaches safe, accurate, controllable, fast and effectively gastric infusion effect, so as to be conducive to experimenter to improve to mouse stomach
The quality and efficiency of administration.
The utility model is described in further detail below in conjunction with the accompanying drawings.
Description of the drawings
Fig. 1 is the structural representation of experiment mice irrigation stomach device in one embodiment of the utility model；
Fig. 2 is the structural representation for protecting bulb in one embodiment of the utility model.
Description of reference numerals：
10- gavage cylinders；11- head ends；The first liquid outlets of 111-；The second liquid outlets of 112-；12- tail ends；101- piston push rods；
102- pistons；103- tooth bars；
20- actively adjusts gear；21- rotating shafts；22- fixed mounts；
31- the first bendable gastric perfusion needles；32- the second bendable gastric perfusion needles；
40- protects bulb；401- drug row collar extensions；402- drug row internal orifices.
Specific embodiment
With reference to embodiments, the above-mentioned He other technical characteristic of the utility model and advantage are made in more detail
Bright.
As shown in figure 1, in an embodiment, experiment mice irrigation stomach device of the present utility model, including gavage cylinder 10, which has
Head end 11 and tail end 12, are provided with piston push rod 101 in gavage cylinder 10, and its one end for going deep into gavage cylinder 10 is provided with colloid piston 102,
And the one side of piston push rod 101 is provided with the jagged tooth bar 103 of a row.Colloid piston 102 can be sealed to gavage cylinder 10,
So as to reduce the error that experimenter is administered to mouse stomach.
In one embodiment, 10 outer surface of gavage cylinder indicates volume graduation indication line, is conducive to experimenter to carry out mouse
When gastric infusion, the accurate volume for determining gastric infusion, excessive to mouse stomach dosage so as to be prevented effectively from experimenter.
In one embodiment, the maximum volume of gavage cylinder 10 is 1mL, and minimum lattice represent 0.01mL.
Wherein, the tail end 12 of gavage cylinder is provided with one and actively adjusts gear 20, actively adjusts on gear 20 and piston push rod 101
103 mutual accurate bite of tooth bar, rotate actively adjust gear can drive piston push rod movement.Thus, being conducive to experimenter
To mouse controllably, lentamente gastric infusion, it is to avoid experimenter excessive to mouse stomach injection speed and cause mouse oesophagus,
The mechanical injuries of gastral cavity, intestinal tube etc..
In one embodiment, actively adjust gear 20 and be connected with the tail end 12 of gavage cylinder by a fixed mount 22.
In one embodiment, actively adjust gear 20 and be connected with fixed mount 22 by a rotating shaft 21.
The head end 11 of gavage cylinder is provided with two liquid outlets, respectively the first liquid outlet 111 and the second liquid outlet 112, respectively
First and second bendable gastric perfusion needle 31,32 is provided with, the first bendable gastric perfusion needle has forward and backward two sections, is arranged into obtuse angle therebetween；
Second bendable gastric perfusion needle 32 have before, during and after three sections, its adjacent two intersegmental into obtuse angle arrange and bending in the same direction.Such as
This, is conducive to experimenter's position from different angles, different to carry out gastric infusion to mouse, it is to avoid irrigation stomach device is to testing people
The sight line of member is blocked, and is conducive to experimenter quickly and accurately to search out the throat entrance of mouse, while designing many of gastric perfusion needle
Individual folding angles α, β, γ, advantageously reduce mechanical injuries of the gastric perfusion needle to mouse oesophagus, gastral cavity etc., improve experimenter
The quality is administered by mouse stomach and efficiency.
In this embodiment, first and second bendable gastric perfusion needle 31,32 is axially arranged along gavage cylinder 10.
In another embodiment, first and second bendable gastric perfusion needle 31,32 between 10 stack shell of gavage cylinder have different folders
Angle, is conducive to experimenter to carry out effectively gastric infusion to the mouse of different age group, different tissues structure.
In one embodiment, the angle α between the front and rear sections of the first bendable gastric perfusion needle 31 is 120 degree；Second bendable gavage
Before pin 32, in intersegmental angle β be 140 degree, in, the angle γ between back segment be 160 degree.
In one embodiment, the length ratio of 31 front and rear sections of the first bendable gastric perfusion needle is 5:11, the second bendable gastric perfusion needle 32
Before, during and after section length ratio be 6:7:3.Specifically, in an embodiment, the front segment length of the first bendable gastric perfusion needle 31
2.5cm, rear segment length 5.5cm；The front segment length 3cm of the second bendable gastric perfusion needle 32, middle segment length 3.5cm, rear segment length 1.5cm.
The head end of first and second bendable gastric perfusion needle 31,32 is equipped with protection bulb 40, and its surface is provided with multiple drug rows
Collar extension 401, inside are provided with multiple drug row internal orifices 402 connected with drug row collar extension 401.In this embodiment, protection bulb 40 is ellipse
Spherical, and 3 groups of drug row collar extensions and drug row internal orifice is provided with, the wherein 1 group head end for facing respective bendable gastric perfusion needle.Protection bulb
This structure be conducive to avoiding gastric infusion excessive velocities and stimulating the oesophagus and stomach lining of mouse, affect mouse healthy water
Flat, or even cause visceral organ injury of mouse etc., then follow-up experimental study is exerted an adverse impact.
In this embodiment, first and second bendable gastric perfusion needle 31,32 is marked with depth instruction line, and which adopts polypropylene
Material is made, the drawbacks of can avoid conventional conventional irrigation stomach device such as metal gastric perfusion needle, it is to avoid metal needle easily causes little
The mechanical injuries of mouse oral cavity, oesophagus and stomach cardiac sphincter etc., while it may also be determined that gastric perfusion needle enters mouse gastral cavity
Depth, is conducive to experimenter to carry out gastric infusion to next mouse, improves the speed of mouse stomach administration, saves gavage and gives
The time of medicine.
The utility model mouse is as follows using idiographic flow with irrigation stomach device：
Experimenter can select any one gastric perfusion needle 31,32 to carry out gastric infusion, often select one of gastric perfusion needle
The liquid outlet that using sealing valve piston seal another gastric perfusion needle is then needed.
For example select the first bendable gastric perfusion needle 31 carry out gastric infusion idiographic flow as follows：
1. experimenter sheds the second bendable gastric perfusion needle 32, seals the second liquid outlet 112, experiment using sealing valve piston
Personnel's right hand rotate counterclockwise actively adjusts gear 20, drives piston push rod 101 to 10 head end 11 of gavage cylinder by tooth bar 103
Direction is moved, and the air in gavage cylinder 10 is extruded away.
2. experimenter's right hand turns clockwise the gear 20 that actively adjust, and drives piston push rod 101 to filling by tooth bar 103
The direction movement of 10 tail end 12 of stomach cylinder, the decrease in air pressure in gavage cylinder 10 promote gavage cylinder 10 to fill by the first bendable
The protection bulb 40 (drug row collar extension 401, drug row internal orifice 402) of stomach pin 31, the first bendable gastric perfusion needle 31, the first liquid outlet 111
Draw appropriate gastric infusion medicine.
3. mouse is fixed on experimenter left by experimenter's right hand crawl mousetail, left hand crawl mouse nape
The centre of the palm, while the tail of mouse is clipped in the left hand little finger of toe of experimenter.
4. experimenter's rotate counterclockwise actively adjusts gear 20, drives piston push rod 101 to gavage cylinder by tooth bar 103
The direction movement of 10 head ends 11, the gavage medicine in gavage cylinder 10 are extruded by certain pressure, and gavage medicine passes through gavage cylinder
10th, the first liquid outlet 111, the first bendable gastric perfusion needle 31, protection bulb 40 (drug row internal orifice 402, drug row collar extension 401), gavage
Medicine is admitted in the distal esophagus of mouse, gastral cavity, and it is safe to mouse, accurate, controllable, fast that such experimenter just completes this
Speed, effectively gastric infusion.
Embodiment described above is only that preferred embodiment of the present utility model is described, not to this practicality
New scope is defined, and on the premise of without departing from the utility model design spirit, those of ordinary skill in the art are to this
Various modifications and improvement that the technical scheme of utility model is made, all should fall into the protection of the utility model claims determination
In the range of.
Claims (10)
1. a kind of experiment mice irrigation stomach device, it is characterised in that including gavage cylinder, which has head end and tail end, in the gavage cylinder
Piston push rod is provided with, its one end for going deep into the gavage cylinder is provided with piston, and the one side of the piston push rod is provided with a gang saw
The tooth bar of dentation；
Wherein, the tail end of the gavage cylinder is provided with one and actively adjusts gear, described actively adjusts on gear and the piston push rod
The mutual accurate bite of tooth bar, rotate and actively adjust gear the piston push rod can be driven to move；The head end of the gavage cylinder sets
There are two liquid outlets, be respectively equipped with first and second bendable gastric perfusion needle, and the first bendable gastric perfusion needle has forward and backward two
Section, is arranged into obtuse angle therebetween；The second bendable gastric perfusion needle have before, during and after three sections, its adjacent two intersegmental into obtuse angle arrange
And bending in the same direction；And, the head end of first and second bendable gastric perfusion needle is equipped with protection bulb, and its surface is provided with
Multiple drug row collar extensions, inside are provided with multiple drug row internal orifices connected with the drug row collar extension.
2. experiment mice irrigation stomach device according to claim 1, it is characterised in that first and second bendable gavage described
Pin is axially arranged along the gavage cylinder.
3. experiment mice irrigation stomach device according to claim 1, it is characterised in that first and second bendable gavage described
There is between pin and the gavage cylinder stack shell different angles.
4. experiment mice irrigation stomach device according to claim 1, it is characterised in that before the first bendable gastric perfusion needle,
Angle between back segment is 120 degree；Before the second bendable gastric perfusion needle, in intersegmental angle be 140 degree, in, between back segment
Angle is 160 degree.
5. experiment mice irrigation stomach device according to claim 1, it is characterised in that the first bendable gastric perfusion needle is forward and backward
The length ratio of section is 5:11, before, during and after the second bendable gastric perfusion needle, the length ratio of section is 6:7:3.
6. experiment mice irrigation stomach device according to claim 1, it is characterised in that the protection bulb is elliposoidal, and sets
There are 3 groups of drug row collar extensions and drug row internal orifice, the wherein 1 group head end for facing respective bendable gastric perfusion needle.
7. experiment mice irrigation stomach device according to claim 1, it is characterised in that first and second bendable gavage described
Pin is marked with depth instruction line.
8. experiment mice irrigation stomach device according to claim 1, it is characterised in that the gavage tube outer surface indicates volume
Graduation indication line.
9. experiment mice irrigation stomach device according to claim 1, it is characterised in that described actively to adjust gear solid by
The tail end for determining frame with the gavage cylinder is connected, and the gear that actively adjusts is connected with the fixed mount by a rotating shaft.
10. experiment mice irrigation stomach device according to claim 1, it is characterised in that first and second bendable gavage described
Pin is made up of polypropylene material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620713847.9U CN206007398U (en) | 2016-07-07 | 2016-07-07 | Experiment mice irrigation stomach device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620713847.9U CN206007398U (en) | 2016-07-07 | 2016-07-07 | Experiment mice irrigation stomach device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206007398U true CN206007398U (en) | 2017-03-15 |
Family
ID=58243486
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201620713847.9U Expired - Fee Related CN206007398U (en) | 2016-07-07 | 2016-07-07 | Experiment mice irrigation stomach device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN206007398U (en) |
-
2016
- 2016-07-07 CN CN201620713847.9U patent/CN206007398U/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20170315 Termination date: 20190707 |