CN205528835U - Cell culture changes bag connecting device - Google Patents
Cell culture changes bag connecting device Download PDFInfo
- Publication number
- CN205528835U CN205528835U CN201620303149.1U CN201620303149U CN205528835U CN 205528835 U CN205528835 U CN 205528835U CN 201620303149 U CN201620303149 U CN 201620303149U CN 205528835 U CN205528835 U CN 205528835U
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- China
- Prior art keywords
- cell culture
- cell
- bottle
- baffle
- baffle plate
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- 238000004113 cell culture Methods 0.000 title claims abstract description 43
- 238000007789 sealing Methods 0.000 claims abstract description 8
- 239000006143 cell culture medium Substances 0.000 claims description 30
- 238000004519 manufacturing process Methods 0.000 abstract description 6
- 230000008901 benefit Effects 0.000 abstract description 4
- 239000003344 environmental pollutant Substances 0.000 abstract 1
- 238000009776 industrial production Methods 0.000 abstract 1
- 231100000719 pollutant Toxicity 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 description 22
- 239000001963 growth medium Substances 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 206010028980 Neoplasm Diseases 0.000 description 3
- 238000005457 optimization Methods 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- 239000000428 dust Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000002649 immunization Methods 0.000 description 2
- 230000003053 immunization Effects 0.000 description 2
- 239000002609 medium Substances 0.000 description 2
- 238000011079 streamline operation Methods 0.000 description 2
- 102000006306 Antigen Receptors Human genes 0.000 description 1
- 108010083359 Antigen Receptors Proteins 0.000 description 1
- 101001117317 Homo sapiens Programmed cell death 1 ligand 1 Proteins 0.000 description 1
- 102100024216 Programmed cell death 1 ligand 1 Human genes 0.000 description 1
- 210000001744 T-lymphocyte Anatomy 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000001815 biotherapy Methods 0.000 description 1
- 239000012930 cell culture fluid Substances 0.000 description 1
- 230000004663 cell proliferation Effects 0.000 description 1
- 238000002659 cell therapy Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 238000001415 gene therapy Methods 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 230000004614 tumor growth Effects 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model discloses a cell culture changes bag connecting device relates to cell industrial production technical field. Cell culture changes bag connecting device, including cell culture base bottle and cell culture bag, set up the bottle lid on the cell culture base bottle, set up the connecting pipe on the bottle lid, the slope sets up the gas outlet on the connecting pipe, the connecting pipe is kept away from cell culture base bottle one end and is set up the switching mouth, the switching mouth is connected with the cell culture bag, set up the baffle in the connecting pipe, the baffle is cylindrical baffle, set up the opening on the baffle, the opening part sets up the dog, the dog is kept away from baffle one side and is set up the spring, the spring is kept away from dog one side and is set up the filter screen, connecting pipe and baffle junction, the baffle all sets up the sealing washer with the dog junction, is the diameter of bottle lid 15 30mm. The utility model has the advantages of this device can be when carrying out the operation of cell culture commentaries on classics bag, the simplified operation flow, and the production time is practiced thrift to the reducing pollutants risk.
Description
Technical field
This utility model relates to cell Industrialized processing technique field, particularly relates to cell cultivation and turns bag connection dress
Put.
Background technology
Tumor vaccine cells treatment is a kind of Celluar and Molecular Biology means that use, enhancing patient's machine
The immune system of body, thus reach the Therapeutic Method suppressing tumor growth even to be eradicated.Substantial amounts of basis
Being proved tumor biotherapy for tumor patient with Clinical Evidence is one safely and effectively means, energy
Enough improve survival of patients treatment, extend life cycle, some patient even can be reached the curative effect cured.PD1
And the howling success that PDL1 antibody and mosaic antigen receptor identification T cell are in terms for the treatment of oncotherapy
Having shown immunization therapy advantage in terms of oncotherapy, immunization therapy certainly will become oncotherapy one can not
Or the means lacked.
Cell of exempting from service is cultivated as in cell gene therapy important and link for core, the effect to cell therapy
Fruit plays decisive role, in practice it has proved that, the cell culture medium bottle that cell culture bags is more traditional than use can be at gas
Body exchanges, and volume of culture and cell proliferation aspect have big advantage, it will cultivate industrialization at cell
Journey more and more uses, but cultivates due to conventional cell and need to use syringe and support etc. careful
Modestly cell culture fluid is poured in cell culture bags, there is intermediary operation many, pollute probability high, operation consumption
Time etc. problem.
Utility model content
For solving deficiency of the prior art, this utility model provides cell cultivation and turns bag attachment means, it
Directly cell culture medium bottle can be connected with cell culture bags when carrying out cell cultivation and turning bag operation
Together, not only streamline operation, also reduce pollution risk, save the production time.
This utility model for achieving the above object, is achieved through the following technical solutions: cell is cultivated and turned bag connection
Device, including cell culture medium bottle and cell culture bags, described cell culture medium bottle arranges bottle cap, described
Arranging connecting tube on bottle cap, described connecting tube communicates with cell culture medium bottle, and described connecting tube is obliquely installed
Gas outlet, described connecting tube arranges converting interface away from cell culture medium bottle one end, and described converting interface is trained with cell
Supporting bag to connect, described converting interface is round table-like reducing from connecting tube one end to cell culture bags one end.
Arranging baffle plate in described connecting tube, described baffle plate is cylindrical baffle, and described baffle plate arranges opening,
Described opening part arranges block, and described block arranges spring away from baffle plate side, and described spring is away from block one
Side arranges drainage screen.
Described connecting tube is respectively provided with sealing ring with baffle plate junction, baffle plate with block junction.
A diameter of 15-30mm of described bottle cap.
Contrast prior art, the beneficial effects of the utility model are:
1, this device is when carrying out cell cultivation and turning bag operation, can directly be trained with cell by cell culture medium bottle
Foster bag links together, and easily cell culture medium is proceeded to cell culture bags, enormously simplify operating process,
Reduce pollution risk, save the production time.
2, the setting of block so that cell culture medium can only flow into cell culture bags from cell culture medium bottle, and
Cell culture medium bottle can not be flowed into from cell culture bags, convenient and reliable, improve the stability of this device.
3, sealing ring can strengthen the seal between baffle plate and connecting tube, baffle plate and block, optimizes further
This device.
4,15-30mm diameter bottle cap is cultivated to turn in bag operation at cell and is flowed, and can give play to and turn bag operation
Maximum efficiency.
Accompanying drawing explanation
For the technical scheme of clearer explanation this utility model embodiment, institute in embodiment being described below
The accompanying drawing used is needed to be briefly described, it is clear that, the accompanying drawing in describing below is only this practicality
Some novel embodiments, for those of ordinary skill in the art, before not paying creative work
Put, it is also possible to obtain other accompanying drawing according to these accompanying drawings.
Accompanying drawing 1 is this utility model structural representation；
Accompanying drawing 2 is this utility model I portion enlarged drawing.
Label shown in accompanying drawing: 1, cell culture medium bottle；2, bottle cap；3, connecting tube；4, gas outlet；5、
Baffle plate；6, block；7, spring；8, drainage screen；9, converting interface；10, cell culture bags；11, open
Mouthful.
Detailed description of the invention
In conjunction with the drawings and specific embodiments, the utility model is described in further detail.Should be understood that these are implemented
Example is merely to illustrate this utility model rather than limits scope of the present utility model.In addition, it is to be understood that readding
After having read the content that this utility model is lectured, this utility model can be made various changing by those skilled in the art
Moving or amendment, these equivalent form of values fall within the application appended claims limited range equally.
Cell is cultivated and is turned bag attachment means, and including cell culture medium bottle 1 and cell culture bags 10, its feature exists
In: bottle cap 2 is set on described cell culture medium bottle 1, described bottle cap 2 arranges connecting tube 3, described connection
Pipe 3 communicates with cell culture medium bottle 1, and described connecting tube 3 is obliquely installed gas outlet 4, gas outlet be connected
Pipe tilts to connect, and both can guarantee that the flowing of culture medium, it is also possible to prevent external factor, enters training such as dust etc.
Supporting in base, reduce and pollute, described connecting tube 3 arranges converting interface 9 away from cell culture medium bottle 1 one end, described
Converting interface 9 is connected with cell culture bags 10, described converting interface 9 from connecting tube 3 one end to cell culture bags 10
One end is round table-like reducing, converting interface be round table-like reduce be provided with beneficially turn bag operation operation.This dress
Put when carrying out cell cultivation and turning bag operation, can directly cell culture medium bottle be connected to cell culture bags
Together, easily cell culture medium is proceeded to cell culture bags, enormously simplify operating process, reduce dirt
Dye risk, saves the production time.
As optimization, arranging baffle plate 5 in described connecting tube 3, described baffle plate 5 is cylindrical baffle, described gear
Arranging opening 11 on plate 5, arrange block 6 at described opening 11, described block 6 sets away from baffle plate 5 side
Putting spring 7, described spring 7 arranges drainage screen 8 away from block 6 side.The setting of block so that cell is trained
Foster base can only flow into cell culture bags from cell culture medium bottle, and can not flow into cell from cell culture bags and cultivate
Base bottle, convenient and reliable, improve the stability of this device.
As optimization, described connecting tube 3 is respectively provided with block 6 junction with baffle plate 5 junction, baffle plate 5
Sealing ring.Sealing ring can strengthen the seal between baffle plate and connecting tube, baffle plate and block, the most excellent
Change this device.
As optimization, a diameter of 15-30mm of described bottle cap 2.15-30mm diameter bottle cap is cultivated at cell
Turn in bag operation and flow, the maximum efficiency turning bag operation can have been given play to.
Embodiment 1:
Cell is cultivated and is turned bag attachment means, including cell culture medium bottle 1 and cell culture bags 10, described cell
Arranging bottle cap 2 on medium bottle 1, described bottle cap 2 arranges connecting tube 3, described connecting tube 3 is trained with cell
Supporting base bottle 1 to communicate, described connecting tube 3 is obliquely installed gas outlet 4, gas outlet tilts to be connected with connecting tube,
Both can guarantee that the flowing of culture medium, it is also possible to prevent external factor, as dust etc. enters in culture medium, reduced
Polluting, described connecting tube 3 arranges converting interface 9 away from cell culture medium bottle 1 one end, and described converting interface 9 is with thin
Born of the same parents' culture bag 10 connects, and described converting interface 9 is round platform from connecting tube 3 one end to cell culture bags 10 one end
Shape reduces, converting interface be round table-like reduce be provided with beneficially turn bag operation operation.This device is being carried out carefully
Born of the same parents cultivate when turning bag operation, can directly be linked together with cell culture bags by cell culture medium bottle, convenient
Cell culture medium is proceeded to cell culture bags by ground, enormously simplify operating process, reduces pollution risk, joint
The about production time.Arranging baffle plate 5 in described connecting tube 3, described baffle plate 5 is cylindrical baffle, described baffle plate
Arranging opening 11 on 5, arrange block 6 at described opening 11, described block 6 is arranged away from baffle plate 5 side
Spring 7, described spring 7 arranges drainage screen 8 away from block 6 side.The setting of block so that cell is cultivated
Base can only flow into cell culture bags from cell culture medium bottle, and can not flow into cell culture medium from cell culture bags
Bottle, convenient and reliable, improve the stability of this device.Described connecting tube 3 and baffle plate 5 junction, baffle plate 5
It is respectively provided with sealing ring with block 6 junction.Sealing ring can strengthen baffle plate and connecting tube, baffle plate and block it
Between seal, optimize this device further.A diameter of 15-30mm of described bottle cap 2.15-30mm
Diameter bottle cap is cultivated to turn in bag operation at cell and is flowed, and can give play to the maximum efficiency turning bag operation.This reality
A kind of cell provided by new embodiment is cultivated and is turned the bottle cap of the bag a diameter of 15-30mm of use by connecting
Cell culture medium bottle is linked together by pipe and converting interface with cell culture bags, owing to there being the existence of gas outlet,
Culture medium can flow into cell culture bags smoothly, it may be necessary to connecting tee valve controlling flow in connecting tube
Speed.The present embodiment provides the benefit that: this device can be when carrying out cell cultivation and turning bag operation, by cell
Medium bottle is directly linked together with cell culture bags, streamline operation, reduces pollution risk, saves
Production time.
Claims (4)
1. cell is cultivated and is turned bag attachment means, including cell culture medium bottle (1) and cell culture bags (10),
It is characterized in that: arrange bottle cap (2) on described cell culture medium bottle (1), described bottle cap (2) is upper to be arranged
Connecting tube (3), described connecting tube (3) communicates with cell culture medium bottle (1), in described connecting tube (3)
Being obliquely installed gas outlet (4), described connecting tube (3) arranges switching away from cell culture medium bottle (1) one end
Mouth (9), described converting interface (9) is connected with cell culture bags (10), and described converting interface (9) is from connection
Pipe (3) one end is round table-like reducing to cell culture bags (10) one end.
Cell the most according to claim 1 is cultivated and is turned bag attachment means, it is characterised in that: described connection
Arranging baffle plate (5) in pipe (3), described baffle plate (5) is cylindrical baffle, and described baffle plate (5) is upper to be arranged
Opening (11), described opening (11) place arranges block (6), and described block (6) is away from baffle plate (5)
Side arranges spring (7), and described spring (7) arranges drainage screen (8) away from block (6) side.
Cell the most according to claim 1 and 2 is cultivated and is turned bag attachment means, it is characterised in that: described
Connecting tube (3) is respectively provided with sealing ring with baffle plate (5) junction, baffle plate (5) with block (6) junction.
Cell the most according to claim 1 is cultivated and is turned bag attachment means, it is characterised in that: described bottle cap
(2) a diameter of 15-30mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620303149.1U CN205528835U (en) | 2016-04-12 | 2016-04-12 | Cell culture changes bag connecting device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620303149.1U CN205528835U (en) | 2016-04-12 | 2016-04-12 | Cell culture changes bag connecting device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN205528835U true CN205528835U (en) | 2016-08-31 |
Family
ID=56791445
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201620303149.1U Active CN205528835U (en) | 2016-04-12 | 2016-04-12 | Cell culture changes bag connecting device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN205528835U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107586717A (en) * | 2017-10-31 | 2018-01-16 | 河南省肿瘤医院 | A kind of attachment means of cell culture bags and culture jar |
-
2016
- 2016-04-12 CN CN201620303149.1U patent/CN205528835U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107586717A (en) * | 2017-10-31 | 2018-01-16 | 河南省肿瘤医院 | A kind of attachment means of cell culture bags and culture jar |
| CN107586717B (en) * | 2017-10-31 | 2024-03-26 | 河南省肿瘤医院 | Connecting device for cell culture bag and culture solution bottle |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20220615 Address after: 361012 unit 431, floor 4, building C, Xiamen international shipping center, No. 93, Xiangyu Road, Xiamen area, China (Fujian) pilot Free Trade Zone, Xiamen, Fujian Patentee after: Xiamen Sany hematopoietic Technology Co.,Ltd. Address before: Room A304, building 10, innovation park, Haixi high tech Industrial Park, Fuzhou high tech Zone, Keji East Road, Shangjie Town, Minhou County, Fuzhou City, Fujian Province 350108 Patentee before: FUJIAN STEMERY TECHNOLOGY CO.,LTD. |