CN205386247U - Antibiotic hemostasis complex film - Google Patents
Antibiotic hemostasis complex film Download PDFInfo
- Publication number
- CN205386247U CN205386247U CN201521057543.3U CN201521057543U CN205386247U CN 205386247 U CN205386247 U CN 205386247U CN 201521057543 U CN201521057543 U CN 201521057543U CN 205386247 U CN205386247 U CN 205386247U
- Authority
- CN
- China
- Prior art keywords
- polycaprolactone
- electrostatic spinning
- spinning membrane
- membrane
- chitosan sponge
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Abstract
The utility model discloses an antibiotic hemostasis complex film, including chitosan sponge layer and polycaprolactone electrostatic spinning membrane layer, the polycaprolactone electrostatic spinning membrane layer comprises upper polycaprolactone electrostatic spinning membrane and the polycaprolactone electrostatic spinning membrane of lower floor, and chitosan sponge level is in the middle of upper polycaprolactone electrostatic spinning membrane and the polycaprolactone electrostatic spinning membrane of lower floor. Upper strata polycaprolactone electrostatic spinning membrane and polycaprolactone electrostatic spinning membrane of lower floor and chitosan sponge layer are passed through the hot -pressing process combination and are in the same place. The utility model discloses the structure is comparatively reasonable, and the material pliability is good, and the porosity is high, and is high with the laminating nature of the surface of a wound, has antibacterial, the hematostatic function of efficient, can also play simultaneously to prevent glutinous efficiency even between the tissue, and used raw materials is chitosan and polycaprolactone, can be by human complete absorption, and it is harmless to the human body, avoided the trouble that the secondary took out.
Description
Technical field
This utility model belongs to medical material tech field, relates generally to a kind of hemostatic material in medical use being applied to clinical field.
Background technology
At present, the Antiadhesive film of prior art, it is generally flexible transparent film, there is certain mechanical strength, after implanting, the form of film can be kept within the intended time, by surgical wound surface and the isolation of adjacent organs tissue, the wound surface being in agglutination is avoided directly to contact with surrounding tissue with effect, thus the generation of bad adhesion can effectively be prevented.But the Antiadhesive film of prior art is monofilm; mechanical strength is low; support effect is poor; preventing adhesiving effect is low, have impact on the quality of operation, all kinds of medical films function singlenesses used in existing clinical operation; medical films properties of product are unsatisfactory; as caused the flexibility of medical films, docile property poor because of product dense micro-structure, it is impossible to well wound is played a protective role, there may come a time when more side reaction.
Polycaprolactone static spinning membrane described in the utility model/chitosan sponge antibacterial anti hemorrhagic composite membrane, chitosan sponge layer has loose structure, there is the effect of hemostasis, and chitosan itself has antibacterial effect, can effectively prevent postoperative antibacterial from infecting, and chitosan can degrade in vivo, catabolite is harmless.Electrostatic spinning rete is that polycaprolactone utilizes the method for electrostatic spinning to prepare into static spinning membrane, PCL electrostatic spinning film toughness is better, and surface is relatively smooth, porosity is high, specific surface area is big, blood can be made to pass through electrostatic spinning rete absorbed by chitosan sponge layer, and its surface is relatively smooth, it is possible to effectively play the effect of anti.Therefore, this utility model is rational in infrastructure, material flexibility good, and porosity is high, high with the stickiness of wound surface, loose, soft, docile, has antibacterial, hemostatic function efficiently, can also play the effect preventing from being adhered between tissue simultaneously；And raw materials used for chitosan with polycaprolactone, it is possible to fully absorbed by human body, harmless, it is to avoid the trouble that secondary takes out.
Utility model content
The purpose of this utility model is to propose a kind of polycaprolactone static spinning membrane/chitosan sponge antibacterial anti hemorrhagic composite membrane, to facilitate the hemorrhage treatment in operation process, simultaneously works as antibacterial and anti effect.
To achieve these goals, this utility model is by the following technical solutions:
A kind of antibacterial anti hemorrhagic composite membrane, including chitosan sponge layer and polycaprolactone electrostatic spinning rete, described polycaprolactone electrostatic spinning rete is made up of upper strata polycaprolactone static spinning membrane and lower floor's polycaprolactone static spinning membrane, and chitosan sponge layer is positioned in the middle of upper strata polycaprolactone static spinning membrane and lower floor's polycaprolactone static spinning membrane.
The thickness of described chitosan sponge layer is 0.5mm-1.5mm, and porosity is 50-70%.
The thickness of described polycaprolactone electrostatic spinning rete is 0.08mm-0.12mm, and the molecular weight of polycaprolactone is 50,000-30 ten thousand.
Described antibacterial anti hemorrhagic composite membrane is by being combined the antibacterial anti hemorrhagic composite membrane made between chitosan sponge layer and polycaprolactone electrostatic spinning rete by the mode of hot pressing.
Compared with prior art, this utility model has the advantages that polycaprolactone of the present utility model static spinning membrane/chitosan sponge antibacterial anti hemorrhagic composite membrane, hemorrhage for what treat in operation process, can effectively stop blooding, and there is antibacterial action simultaneously, there is the advantage that cure rate height, expense are relatively low；This utility model polycaprolactone static spinning membrane/chitosan sponge antibacterial anti hemorrhagic composite membrane can be fully absorbed by human body, and catabolite is completely harmless to human body, has the feature of tissue adhesion concurrently simultaneously, it is to avoid the trouble that second operation is removed；This utility model polycaprolactone static spinning membrane/chitosan sponge antibacterial anti hemorrhagic composite membrane adopts three-decker to arrange simultaneously, there is stronger mechanical strength and toughness, pliability is better, carrying out that can be random is folding and bends, well can fit with wound surface, it is possible to significantly more efficient stop blooding.
Accompanying drawing explanation
Fig. 1 is structural representation of the present utility model.
Detailed description of the invention
As shown in Figure 1, a kind of antibacterial anti hemorrhagic composite membrane, including chitosan sponge layer and polycaprolactone electrostatic spinning rete, described polycaprolactone electrostatic spinning rete is made up of upper strata polycaprolactone static spinning membrane 11 and lower floor's polycaprolactone static spinning membrane 12, and chitosan sponge layer 2 is positioned in the middle of upper strata polycaprolactone static spinning membrane 11 and lower floor's polycaprolactone static spinning membrane 12.
The thickness of chitosan sponge layer is 0.5mm-1.5mm, and porosity is 50-70%；The thickness of described polycaprolactone electrostatic spinning rete is 0.08mm-0.12mm, and the molecular weight of polycaprolactone is 50,000-30 ten thousand；Described antibacterial anti hemorrhagic composite membrane by combining the antibacterial anti hemorrhagic composite membrane made by the mode of hot pressing between chitosan sponge layer and polycaprolactone electrostatic spinning rete, the size of antibacterial anti hemorrhagic composite membrane carries out cutting according to practical situation.
The preparation method of this utility model antibacterial anti hemorrhagic composite membrane is as follows: takes the polycaprolactone (PCL) that molecular weight is 5-30 ten thousand (such as 50,000,100,000,200,000,300,000) and is configured to electrostatic spinning raw material solution, join in syringe, utilize electrostatic spinning nozzle, corresponding parameter is set, namely prepares PCL static spinning membrane.Then on PCL static spinning membrane, spread correspondingly sized chitosan sponge, then upload, at chitosan sponge, the PCL static spinning membrane that paving is a layer correspondingly sized, the method that trilaminate material utilizes hot pressing carries out compound, namely obtain polycaprolactone static spinning membrane/chitosan sponge antibacterial anti hemorrhagic composite membrane, and then carry out packing and irradiation sterilization.
The beneficial effects of the utility model are polycaprolactone static spinning membrane/chitosan sponge antibacterial anti hemorrhagic composite membranes is that three-decker is arranged, and has stronger mechanical strength and toughness, hemostatic and antibacterial and preventing adhesiving effect good, improves the quality of operation.
Above-described embodiment, simply to illustrate that technology of the present utility model design and feature, its objective is to be in that to allow one of ordinary skilled in the art will appreciate that content of the present utility model and to implement according to this, can not limit protection domain of the present utility model with this.The change of every equivalence done by the essence of this utility model content or modification, all should be encompassed in protection domain of the present utility model.
Claims (2)
1. an antibacterial anti hemorrhagic composite membrane, it is characterized in that: include chitosan sponge layer and polycaprolactone electrostatic spinning rete, described polycaprolactone electrostatic spinning rete is made up of upper strata polycaprolactone static spinning membrane (11) and lower floor's polycaprolactone static spinning membrane (12), and chitosan sponge layer (2) is positioned in the middle of upper strata polycaprolactone static spinning membrane (11) and lower floor's polycaprolactone static spinning membrane (12)；The thickness of described chitosan sponge layer is 0.5mm-1.5mm, and porosity is 50-70%；The thickness of described polycaprolactone electrostatic spinning rete is 0.08mm-0.12mm, and the molecular weight of polycaprolactone is 50,000-30 ten thousand.
2. antibacterial anti hemorrhagic composite membrane according to claim 1, it is characterised in that: described antibacterial anti hemorrhagic composite membrane is by being combined the antibacterial anti hemorrhagic composite membrane made between chitosan sponge layer and polycaprolactone electrostatic spinning rete by the mode of hot pressing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201521057543.3U CN205386247U (en) | 2015-12-18 | 2015-12-18 | Antibiotic hemostasis complex film |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201521057543.3U CN205386247U (en) | 2015-12-18 | 2015-12-18 | Antibiotic hemostasis complex film |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN205386247U true CN205386247U (en) | 2016-07-20 |
Family
ID=56381088
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201521057543.3U Active CN205386247U (en) | 2015-12-18 | 2015-12-18 | Antibiotic hemostasis complex film |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN205386247U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113684605A (en) * | 2021-09-08 | 2021-11-23 | 佛山(华南)新材料研究院 | Preparation method of bionic medical anti-adhesion membrane |
| CN115154642A (en) * | 2022-07-05 | 2022-10-11 | 福州大学 | Bionic asymmetric sponge dressing and preparation method thereof |
-
2015
- 2015-12-18 CN CN201521057543.3U patent/CN205386247U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113684605A (en) * | 2021-09-08 | 2021-11-23 | 佛山(华南)新材料研究院 | Preparation method of bionic medical anti-adhesion membrane |
| CN115154642A (en) * | 2022-07-05 | 2022-10-11 | 福州大学 | Bionic asymmetric sponge dressing and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN100400019C (en) | Emergency wound dressing and its preparation method | |
| CN108014366A (en) | A kind of marine organism material composite hydrogel dressing and preparation method thereof | |
| RU2009127718A (en) | WOUND OR TISSUE BANDING MATERIAL CONTAINING LACTIC ACID BACTERIA | |
| CN103394116A (en) | Hydrogel dressing capable of promoting wound healing and preparation method thereof | |
| EP2326336A4 (en) | Tissue scaffolds derived from forestomach extracellular matrix | |
| CN102921050A (en) | Preparation method of anti-adhesion fibrous membrane with hemostatic function | |
| CN103768650A (en) | Wound regenerating and repairing bandage and manufacture method thereof | |
| US20160193106A1 (en) | Tissue repair devices utilizing self-assembled materials | |
| CN105287106A (en) | Bandage dressing special for limb war wound first aid | |
| GB2434105A (en) | Fibronectin-modified ECM tissue graft constructs and methods for preparation and use thereof | |
| CN106310373A (en) | Biological repair membrane and preparation method thereof | |
| Kim et al. | Tympanic membrane regeneration using a water-soluble chitosan patch | |
| CN105833331A (en) | Preparation method for degradable biological wound dressing and obtained product | |
| CN205386247U (en) | Antibiotic hemostasis complex film | |
| US20140213548A1 (en) | System and method for hemostatic wound dressing | |
| CN103316380A (en) | Bone defect repairing material, preparation method and applications thereof | |
| CN105288698A (en) | Calcium alginate composite medical surgical dressing and preparation method thereof | |
| CN208448217U (en) | A kind of anti-bacterial hydrogel dressing | |
| RU2014113441A (en) | MEDICAL MULTI-LAYER BANDAGE WITH MULTIFUNCTION NANOMEMBRANES AND PRODUCTS BASED ON ITS | |
| CN105434107A (en) | Silica gel vacuum sealing drainage dressing | |
| CN203195854U (en) | Hyaluronic acid group waterproof hemostatic sponge | |
| CN201286796Y (en) | Anti-blocking hemostasia film with multi-layer composite structure | |
| CN109432479B (en) | Antibacterial hemostatic hydrocolloid oily yarn and preparation method thereof | |
| CN104324413A (en) | Preparation method of hydrogel dressing | |
| CN203619954U (en) | Skin repair membrane |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20171228 Address after: 450045, No. 2, unit 2, unit 2, No. 6, North Ring Road, Jinshui District, Zhengzhou, Henan Patentee after: Henan Medical Technology Intelligent Technology Co., Ltd. Address before: 451191 Xinzheng, Henan, Longhu, No. 1,, Patentee before: Henan Institute of Engineering |
|
| TR01 | Transfer of patent right |