CN204369902U - A kind of hold-down mechanism of multi-layer cellular culture plate - Google Patents
A kind of hold-down mechanism of multi-layer cellular culture plate Download PDFInfo
- Publication number
- CN204369902U CN204369902U CN201420767392.XU CN201420767392U CN204369902U CN 204369902 U CN204369902 U CN 204369902U CN 201420767392 U CN201420767392 U CN 201420767392U CN 204369902 U CN204369902 U CN 204369902U
- Authority
- CN
- China
- Prior art keywords
- transverse axis
- culture plate
- stationary shaft
- hold
- down mechanism
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model provides a kind of hold-down mechanism of multi-layer cellular culture plate, and its energy pressure strip lid and orifice plate, guarantee stopping property, and effectively can compress the Tissue Culture Plate after multiple stacking, and improves the utilization ratio in shaking table space.It comprises transverse axis, support, stationary shaft and axle sleeve, transverse axis two ends are supported by a pack support, support is fixed on base plate, transverse axis is provided with axle sleeve, stationary shaft is installed on axle sleeve and can vertically moves up and down, the lower end of stationary shaft is provided with pressure pad, also comprises the fixed mechanism that restriction stationary shaft vertically moves up and down.
Description
Technical field
The utility model relates to the stationary installation of Tissue Culture Plate, is specifically related to a kind of hold-down mechanism of multi-layer cellular culture plate.
Background technology
Along with molecular biological development, the heterogenous expression technology of albumen is ripe gradually and be widely used.The expression of foreign protein needs to select suitable expressive host and Expression element, and this just needs to build huge expression library, therefrom selects preferably representation aids box.Tissue Culture Plate can utilize less nutrient solution to carry out the screening of high-flux cell cultivation and bacterial classification, cell strain and expression library, has fast, high-throughput, the feature such as cost-saving.
Existing Tissue Culture Plate is in use in order to avoid crossed contamination between microbiological contamination or plate hole, need to seal plate mouth, now mainly contain two kinds of sealing plate mouth modes, one is that latex mattress is sealed, one is the sealing of " sandwich " formula plate lid, " sandwich " formula plate lid well can carry out gaseous interchange, avoids crossed contamination.But stopping property cannot ensure when plate lid and orifice plate are combined, and need specifically to cultivate shaking table.And the size in orifice plate shaking table plate face when shaking table is cultivated has limited to the orifice plate number that can cultivate simultaneously.And shaking table solid space can not be utilized effectively.
Summary of the invention
For the problems referred to above, the utility model provides a kind of hold-down mechanism of multi-layer cellular culture plate, and its energy pressure strip lid and orifice plate, guarantee stopping property, and effectively can compress the multiple Tissue Culture Plates after stacking, and improves the utilization ratio in shaking table space.
Its technical scheme is such, comprise transverse axis, support, stationary shaft and axle sleeve, described transverse axis two ends are supported by a pack support, described support is fixed on base plate, described transverse axis is provided with axle sleeve, described stationary shaft is installed on described axle sleeve and can vertically moves up and down, and the lower end of described stationary shaft is provided with pressure pad, also comprises the fixed mechanism that the described stationary shaft of restriction vertically moves up and down.
Further, described fixed mechanism comprises fixed block, and described fixed block is provided with internal thread, and described stationary shaft bottom is provided with the outside screw mated with the internal thread of described fixed block, and described fixed block is threaded with described stationary shaft.
Further, described fixed block outer edge surface is provided with cross swivel mount.
Further, described support is vertically placed with transverse axis fixed orifices, and the end of described transverse axis is supported in described transverse axis fixed orifices.
Further, described transverse axis end is provided with axial installation cavity, is provided with spring pin in described installation cavity, and described spring pin can along described transverse axis axial stretching.
Further, the outer edge surface of described transverse axis is provided with the stopper slot of installation cavity described in UNICOM, and the shank of described spring pin is provided with shifting block, and described shifting block passes described stopper slot and exposes to the outer edge surface of described transverse axis.
Further, also comprise strongback, described strongback is arranged between the plate lid of the Tissue Culture Plate to be compressed of pressure pad and top layer, described strongback lower surface is provided with locating slot, the upper end of strut member is supported in locating slot, make to be provided with space between the plate lid of Tissue Culture Plate and strongback, described stationary shaft press-fits the upper surface of described strongback.
After adopting structure of the present utility model, its beneficial effect is: some Tissue Culture Plates to be stacked between a pack support and to be compressed by stationary shaft, stationary shaft can vertically move up and down, and fixed by fixed mechanism, its energy pressure strip lid and orifice plate, guarantee stopping property, and the Tissue Culture Plate that can effectively compress after multiple stacking, ensure that under same culture condition, carry out the screening of more planks simultaneously, improve the utilization ratio in shaking table space and the screening efficiency of cell; Fixed mechanism comprises fixed block, fixed block is provided with internal thread, stationary shaft bottom is provided with the outside screw mated with the internal thread of fixed block, fixed block is threaded with stationary shaft, and support is vertically placed with transverse axis fixed orifices, and the end of transverse axis is supported in transverse axis fixed orifices, the increase of Tissue Culture Plate and convenient to remove, fast, only need move up and down the position of transverse axis on support, rotate cross rotary fixing frame and compress.
Accompanying drawing explanation
Fig. 1 is structural representation of the present utility model;
Fig. 2 is the structural representation in Fig. 1 after A place partial enlargement.
Embodiment
As shown in Figure 1 to Figure 2, comprise transverse axis 3, support 2, stationary shaft 5 and axle sleeve 4, transverse axis 3 two ends are supported by a pack support 2, support 2 is fixed on base plate 1, transverse axis 3 is provided with axle sleeve 4, stationary shaft 5 is installed on axle sleeve 4 and can vertically moves up and down, and the lower end of stationary shaft 5 is provided with pressure pad 17, also comprises the fixed mechanism that restriction stationary shaft 5 vertically moves up and down, fixed mechanism comprises fixed block, and fixed block is provided with internal thread, and stationary shaft 5 bottom is provided with the outside screw mated with the internal thread of fixed block, and fixed block is threaded with stationary shaft 5, fixed block outer edge surface is provided with cross swivel mount 12, support 2 is vertically placed with transverse axis fixed orifices 11, and the end of transverse axis 3 is supported in transverse axis fixed orifices 11, transverse axis 3 end is provided with axial installation cavity 9, is provided with spring pin in installation cavity 9, and spring pin comprises shank 6 and spring 8, and spring is against the bottom face of shank 6 and installation cavity 9, and shank 6 can under the action of the spring can along transverse axis 3 axial stretching, the outer edge surface of transverse axis 3 is provided with the stopper slot 10 of UNICOM's installation cavity 9, and the shank of spring pin is provided with shifting block 7, and shifting block 7 passes stopper slot 10 and exposes to the outer edge surface of transverse axis 3, also comprise strongback 16, some Tissue Culture Plates are stacked on base plate 1, and be positioned at immediately below stationary shaft 5, the upper surface of the plate lid 13 of Tissue Culture Plate is provided with strut member 14, the lower surface of its orifice plate 15 is provided with locating slot, the upper end of strut member 14 is supported in locating slot, make to be provided with space between the plate lid 13 of downside Tissue Culture Plate and the orifice plate 15 of upside Tissue Culture Plate, the quantity of strut member and locating slot is five, be distributed in culture plate lid and strongback corner and center, strongback is arranged between the plate lid of pressure pad and top cell culture plate to be compressed, strongback 16 lower surface is provided with locating slot, the plate that strongback is placed in Tissue Culture Plate covers, the upper end of strut member is supported in locating slot, make to be provided with space between the plate lid of Tissue Culture Plate and strongback, strongback 16 is arranged between the plate lid of pressure pad 17 and Tissue Culture Plate to be compressed, stationary shaft 5 press-fits the upper surface of strongback 16.
This hold-down mechanism is applicable to the cultivation of the various kinds of cell types such as microorganism, mammalian cell, vegetable cell, insect cell, meanwhile, is also applicable to the cell cultures mode that this two class of suspension culture and adherent culture is different.
Concrete operating process is as follows:
First rotary cross swivel mount, unclamps fixed block, inwardly pulls shifting block simultaneously, shank is inwardly shunk, moves up and down transverse axis, until move to suitable fixed orifices, unclamp shifting block, shank front end is plugged in fixed orifices, thus fixing transverse axis.Successively by adding substratum, inoculated culture plate is stacked in the groove of base plate, this groove is between adjacent support, for proliferative rate plate, place appropriate after, on top layer culture plate, put into strongback, strongback plays location and is fixed the effect of culture plate, screw cross swivel mount, make pressure pad compress strongback, base plate is put into shaking table, and be secured by bolts in shaking table plate face, fix rear operation shaking table and cultivate.One group of press mounting structure can fix polylith Tissue Culture Plate simultaneously, and can arrange position or the quantity of the fixed orifices on support according to the quantity of Tissue Culture Plate.
Claims (7)
1. the hold-down mechanism of a multi-layer cellular culture plate, comprise transverse axis, support, stationary shaft and axle sleeve, described transverse axis two ends are supported by a pack support, described support is fixed on base plate, described transverse axis is provided with axle sleeve, described stationary shaft is installed on described axle sleeve and can vertically moves up and down, and the lower end of described stationary shaft is provided with pressure pad, also comprises the fixed mechanism that the described stationary shaft of restriction vertically moves up and down.
2. the hold-down mechanism of a kind of multi-layer cellular culture plate according to claim 1, it is characterized in that: described fixed mechanism comprises fixed block, described fixed block is provided with internal thread, described stationary shaft bottom is provided with the outside screw mated with the internal thread of described fixed block, and described fixed block is threaded with described stationary shaft.
3. the hold-down mechanism of a kind of multi-layer cellular culture plate according to claim 2, is characterized in that: described fixed block outer edge surface is provided with cross swivel mount.
4. the hold-down mechanism of a kind of multi-layer cellular culture plate according to Claims 2 or 3, is characterized in that: described support is vertically placed with transverse axis fixed orifices, and the end of described transverse axis is supported in described transverse axis fixed orifices.
5. the hold-down mechanism of a kind of multi-layer cellular culture plate according to claim 4, is characterized in that: described transverse axis end is provided with axial installation cavity, is provided with spring pin in described installation cavity, described spring pin can along described transverse axis axial stretching.
6. the hold-down mechanism of a kind of multi-layer cellular culture plate according to claim 5, it is characterized in that: the outer edge surface of described transverse axis is provided with the stopper slot being communicated with described installation cavity, the shank of described spring pin is provided with shifting block, and described shifting block passes described stopper slot and exposes to the outer edge surface of described transverse axis.
7. the hold-down mechanism of a kind of multi-layer cellular culture plate according to claim 6, it is characterized in that: also comprise strongback, described strongback lower surface is provided with locating slot, described strongback is arranged between the plate lid of pressure pad and top layer Tissue Culture Plate to be compressed, the upper end of strut member to be supported in locating slot and to make to be provided with space between the plate lid of Tissue Culture Plate and strongback, and described stationary shaft press-fits the upper surface of described strongback.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420767392.XU CN204369902U (en) | 2014-12-09 | 2014-12-09 | A kind of hold-down mechanism of multi-layer cellular culture plate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420767392.XU CN204369902U (en) | 2014-12-09 | 2014-12-09 | A kind of hold-down mechanism of multi-layer cellular culture plate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN204369902U true CN204369902U (en) | 2015-06-03 |
Family
ID=53326137
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420767392.XU Active CN204369902U (en) | 2014-12-09 | 2014-12-09 | A kind of hold-down mechanism of multi-layer cellular culture plate |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN204369902U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104371922A (en) * | 2014-12-09 | 2015-02-25 | 常州英德生物科技有限公司 | Pressing mechanism for multi-layer tissue culture plates |
| WO2018090035A1 (en) * | 2016-11-14 | 2018-05-17 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Apparatus for reconfiguration of components in a microphysiological system |
-
2014
- 2014-12-09 CN CN201420767392.XU patent/CN204369902U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104371922A (en) * | 2014-12-09 | 2015-02-25 | 常州英德生物科技有限公司 | Pressing mechanism for multi-layer tissue culture plates |
| WO2018090035A1 (en) * | 2016-11-14 | 2018-05-17 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Apparatus for reconfiguration of components in a microphysiological system |
| US11261414B2 (en) | 2016-11-14 | 2022-03-01 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Apparatus for reconfiguration of components in a microphysiological system |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN204369902U (en) | A kind of hold-down mechanism of multi-layer cellular culture plate | |
| CN202658162U (en) | Multi-chamber co-culture device | |
| CN111334407A (en) | Process technology and process equipment for preparing yeast culture by deep fermentation of yeast | |
| CN202849409U (en) | Cell co-culture bottle | |
| CN204325374U (en) | A kind of press mounting structure of multi-layer cellular culture plate | |
| CN104371922B (en) | The compression mechanism of multi-layer cellular culture plate | |
| CN104371921A (en) | Press-fitting structure for multi-layer tissue culture plates | |
| CN205874449U (en) | Be used for ordate houttuynia general flavone to cervical cancer cell line research observation culture dish | |
| CN204434631U (en) | A kind of structure of cell cultures board clamp | |
| CN204918603U (en) | Cell co -culture system under pressure environment | |
| CN205676484U (en) | Egg mother cell and embryo transporting device | |
| CN205999369U (en) | Culture dish placing box is used in a kind of experiment | |
| CN201545842U (en) | Direct-contact-type cell coculture device | |
| CN104663438A (en) | Tide-type plant tissue culture device and systematic culture device | |
| CN103406163A (en) | Shaking incubator with four layers independent in temperature control | |
| CN203866306U (en) | Shake-flask culture device | |
| CN204434633U (en) | The structure of a kind of Tissue Culture Plate and plate lid thereof | |
| CN203048939U (en) | Novel sealed anti-vibration culture dish | |
| CN204918614U (en) | Cell culture household utensils | |
| CN204939497U (en) | A kind of cell culture bags | |
| CN206736278U (en) | A kind of stem cell scale expands passage oscillator | |
| CN208191625U (en) | A kind of edible fungus species cultivation fermentor | |
| CN204325373U (en) | A kind of structure of Deep-hole cell culture plate fixture | |
| CN203400736U (en) | Four-layer type shaking cultivation box | |
| CN104403945A (en) | Cell culture plate fixture structure |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |