CN204354514U - A kind of compressing dry granulation machine - Google Patents
A kind of compressing dry granulation machine Download PDFInfo
- Publication number
- CN204354514U CN204354514U CN201420839502.9U CN201420839502U CN204354514U CN 204354514 U CN204354514 U CN 204354514U CN 201420839502 U CN201420839502 U CN 201420839502U CN 204354514 U CN204354514 U CN 204354514U
- Authority
- CN
- China
- Prior art keywords
- dry granulation
- granulation machine
- tablet press
- compressing dry
- straight feeding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000007908 dry granulation Methods 0.000 title claims abstract description 20
- 230000007246 mechanism Effects 0.000 claims abstract description 69
- 238000000034 method Methods 0.000 claims abstract description 17
- 230000008569 process Effects 0.000 claims abstract description 17
- 238000007599 discharging Methods 0.000 claims abstract description 8
- 235000020985 whole grains Nutrition 0.000 claims description 9
- 238000001816 cooling Methods 0.000 claims description 3
- 239000000843 powder Substances 0.000 abstract description 15
- 239000003814 drug Substances 0.000 abstract description 12
- 230000005540 biological transmission Effects 0.000 abstract description 2
- 239000002245 particle Substances 0.000 description 9
- 238000004140 cleaning Methods 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 230000000694 effects Effects 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000009877 rendering Methods 0.000 description 3
- 230000008859 change Effects 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- ZOMNIUBKTOKEHS-UHFFFAOYSA-L dimercury dichloride Chemical compound Cl[Hg][Hg]Cl ZOMNIUBKTOKEHS-UHFFFAOYSA-L 0.000 description 2
- 230000033001 locomotion Effects 0.000 description 2
- 238000003825 pressing Methods 0.000 description 2
- 238000005096 rolling process Methods 0.000 description 2
- 230000008901 benefit Effects 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 229940075397 calomel Drugs 0.000 description 1
- 238000000748 compression moulding Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 230000008676 import Effects 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
Abstract
The utility model discloses a kind of compressing dry granulation machine, belong to medicine instrument field, comprise casing, power-equipment is located in casing, and process equipment is fixed on cabinet exterior; Described process equipment comprises vertical feed mechanism, straight feeding mechanism, pre-tablet press mechanism, broken granulating mechanism and is arranged at the producer agency of broken granulating mechanism bottom; The hopper centre of described vertical feed mechanism is provided with hollow vertical screw rod; the feeding port of straight feeding mechanism is connected with the discharging opening of vertical feed mechanism; straight feeding is in-house is provided with horizontal screw bolt; between the dancer that the discharging opening of straight feeding mechanism is located at pre-tablet press mechanism and stationary roll, described broken granulating mechanism is located at the bottom of tablet press mechanism.The compressing dry granulation machine that the utility model provides is by processing district and power transmission district is completely isolated and profile is clean and tidy; Adopt two-stage feed, performance is better than the domestic one-level feed generally used, and makes medicinal powder fully degassed, uniform feeding and closely knit.
Description
Technical field
The utility model belongs to medicine instrument field, is specifically related to a kind of compressing dry granulation machine.
Background technology
In medicine particle production process, because dry powder quality is light, poor fluidity, directly dry powder is used for granulation, difficulty is large, and production efficiency is low, and the particle made is also easily broken.Therefore, people adopt and first dry powder are pressed into bulk or on chip greatly, then medicine are broken into the particle of suitable size, improve the robustness of particle.Meanwhile, dry granulation, without the need to through process that is wet and heat, can shorten man-hour, reduce production equipment, especially concerning by wet, that heat is perishable medicine, more can improve its product quality.But power-section and the processing district of current most of compressing dry granulation machine are in the same space, easily pollute medicine, and be unfavorable for that the cleaning of equipment is installed.
Utility model content
The purpose of this utility model is to provide a kind of compressing dry granulation machine.
Based on above-mentioned purpose, the utility model adopts following technical scheme: a kind of compressing dry granulation machine, the process equipment comprising casing, be located at the power-equipment in casing and be located on cabinet exterior; Described process equipment comprises vertical feed mechanism, straight feeding mechanism, pre-tablet press mechanism, broken granulating mechanism and is arranged at the producer agency of broken granulating mechanism bottom; Hollow vertical screw rod is provided with in described vertical feed mechanism; the feeding port of straight feeding mechanism is connected with the discharging opening of vertical feed mechanism; straight feeding is in-house is provided with horizontal screw bolt; between the dancer that the discharging opening of straight feeding mechanism is located at pre-tablet press mechanism and stationary roll, described broken granulating mechanism is located at the bottom of tablet press mechanism.
Described straight feeding mechanism is connected with vacuum extractor.
Described broken granulating mechanism comprises blade type breaker and whole grain device, and described whole grain device comprises cylinder and is fixed on the axial blade on cylinder, is provided with board-like sieve, makes the life of sieve, and prevent from polluting medicine because of screen cloth fracture of wire outside cylinder.
Described dancer and fixing roller surface are provided with the straight burr of arc.
Described dancer and stationary roll inner hollow, be connected with cooling device.
Described tablet press mechanism outside is provided with transparent cloche.
Described producer agency is single-punch tablet press, and comprise upper plunger, middle mould and lower plunger, described upper plunger is arranged in above mould, and lower plunger is arranged in below mould, the bottom of upper plunger, the upper end of lower plunger all can insert in nib.
Described producer agency bottom is provided with wheel, and wheel is positioned at slideway, can light mobile producer agency, is convenient to clean producer agency.
Compared with prior art, the utility model has following advantage:
(1) the compressing dry granulation machine that provides of the utility model is by processing district and power transmission district is completely isolated and profile clean and tidy, and dismounting cleaning is easy, and the clean closed achieved from powder to particle is produced;
(2) the utility model adopts two-stage feed, and performance is better than the domestic one-level feed generally used
,make medicinal powder fully degassed, uniform feeding and closely knit, the material of especially comparatively light to some, poor fluidity, further increases intensity in blocks, controls the vibrations of exhaust preferably, improve the yield rate of particle.
Accompanying drawing explanation
Fig. 1 is front view of the present utility model;
Fig. 2 is left view of the present utility model.
Detailed description of the invention
Below in conjunction with accompanying drawing, the utility model is described in detail.
As depicted in figs. 1 and 2, a kind of compressing dry granulation machine, comprises casing 7, is located at the power-equipment in casing 7, is located at the process equipment on casing 7 outer wall; Described process equipment comprises vertical feed mechanism 2, straight feeding mechanism 6, tablet press mechanism 3, broken granulating mechanism 5 and is located at the producer agency 8 of broken granulating mechanism 5 bottom; Hollow vertical screw rod is provided with in described vertical feed mechanism 2; the feeding port of straight feeding mechanism 6 is connected with the discharging opening of vertical feed mechanism 2; straight feeding mechanism 6 inside is provided with horizontal screw bolt; between the dancer 31 that the discharging opening of straight feeding mechanism 6 is located at pre-tablet press mechanism 3 and stationary roll 32, described broken granulating mechanism 5 is located at the bottom of tablet press mechanism 3.
Described straight feeding mechanism 6 is connected with vacuum extractor 61.
Described broken granulating mechanism 5 comprises the breaker 51 of blade type and whole grain device 52, and described whole grain device comprises cylinder and is fixed on the axial blade on cylinder, is provided with board-like sieve outside cylinder.
Described dancer 31 and stationary roll 32 surface are provided with the straight burr of arc, the gas be conducive in pressing process is vented again, described dancer 31 designs for chute type, dancer 31 is floated flexibly under the effect of power-equipment, followability is strong, namely dancer 31 follows adjustment voluntarily with the change of feeding amount size and pressure, ensure that the uniformity of compressing tablet hardness, is conducive to improving yield rate.
Described dancer 31 and stationary roll 32 inner hollow, be connected with cooling device, and prevent tablet press mechanism overheated and destroy the quality of medicine, the import and export mix is built-in, workspace and outside clean area are polluted without leaking may, and be convenient to cleaning.
Described tablet press mechanism 3 outside is provided with transparent cloche 4.
Described producer agency 8 is single-punch tablet press, comprise upper plunger 81, middle mould 82, lower plunger 83, described upper plunger 81 is arranged in above mould 82, and lower plunger 83 is arranged in below mould 82, the bottom of upper plunger 81, the upper end of lower plunger 83 all can insert in mould 82 hole.
Described producer agency 8 bottom is provided with wheel, and wheel is positioned in the middle of slideway 84, when needs cleaning producer agency 8, producer agency 8 can be pushed on one side along slideway, be convenient to cleaning, and reduce the working strength of operating personnel.
Operation principle: the compressing dry granulation machine that the utility model provides, by calomel mercurous chloride through degassed even feeding → precommpression → pre-compression molding → broken whole grain → film-making five steps under the condition not adding auxiliary material, tablet is pressed into after making irregular particle, complete the physical change process from powder to tablet, be specially
1, for material process: dry powder enters funnel 21 through charge door 1, under the effect of hollow vertical screw rod, powder is pushed straight feeding mechanism 6, in this process, portion gas is upwards taken out of through screw rod hollow part by bottom screw rod, and powder can be admitted in horizontal screw bolt feeding port uniformly, ensure screw rod fill full, evenly, not empty, do not block up, and make the density of powder obtain preliminary raising, for the quality of second level feed lays the foundation.Medicinal powder after degassed enters straight feeding mechanism 6, highdensity medicinal powder will be carried force to send into tablet press mechanism 3 under the effect of vacuum extractor 61 and horizontal screw bolt, complete precompressed work, the air content entered in the medicinal powder of tablet press mechanism 3 is reduced to minimum, to ensure the quality of compressing tablet, improve output and yield rate, also make equipment run more steady, reliable; Feeding speed frequency conversion is adjustable.
2, pre-sheeting process: the medicinal powder after degassed has possessed the optimum state before pressure rolling, one is through the precompressed of secondary screw feeding, pressure makes the friction of the medicine and dancer 31 and stationary roll 32 surface entering occlusal area improve, decrease the friction of medicine, increase nip angle, two be degassed after medicine make in pressur rolling forming process equipment run more steady, even intensity in blocks, steady quality, become by dancer 31 cross section to be the friction that the straight burr of camber can further improve medicine and tablet press mechanism with stationary roll 32 surface design, and the gas be conducive in pressing process is vented again, sheet after shaping, through the whole grain of lower operation, pulverization rate obviously declines, ensure that the final mass of product to greatest extent.The speed frequency conversion of running roller is adjustable.
3, whole grain operation: tablet enters broken granulating mechanism 5, under the extruding of blade, is extruded and is broken for granule, satisfactory particle is discharged by board-like sieve.
4, film-making operation: the particle sifted out has stronger mobility, enters producer agency 8, under the effect of upper plunger 81, middle mould 82, lower plunger 83, be pressed into tablet.
Single-punch tablet press work time, its operation principle is prior art, namely lower plunger motion 81 to extreme lower position by charging mechanism to fill material in middle mould 82; When charging mechanism turns on, upper plunger 83 is descending, is shaped by the express material in middle mould 82 an actor's rendering of an operatic tune; After upper plunger 81 enters middle mould 82 to bosom, upper plunger 81 continues up, lower plunger 83 is also up subsequently, and (upper plunger 81 first moves, dynamic after lower plunger 83), after upper plunger 81 leaves middle mould 82 an actor's rendering of an operatic tune, the tablet of extrusion molding is just ejected middle mould 82 an actor's rendering of an operatic tune by lower plunger 83, simultaneously by the rotation of charging mechanism, utilize charging mechanism chassis outer rim to be released by tablet, lower plunger 83 fast movement is to extreme lower position simultaneously, continues next tableting processes.
Claims (8)
1. a compressing dry granulation machine, is characterized in that, the process equipment comprising casing, be located at the power-equipment in casing and be located on cabinet exterior; Described process equipment comprises vertical feed mechanism, straight feeding mechanism, pre-tablet press mechanism, broken granulating mechanism and is arranged at the producer agency of broken granulating mechanism bottom; Hollow vertical screw rod is provided with in described vertical feed mechanism; the feeding port of straight feeding mechanism is connected with the discharging opening of vertical feed mechanism; straight feeding is in-house is provided with horizontal screw bolt; between the dancer that the discharging opening of straight feeding mechanism is located at pre-tablet press mechanism and stationary roll, described broken granulating mechanism is located at the bottom of tablet press mechanism.
2. compressing dry granulation machine according to claim 1, is characterized in that, described straight feeding mechanism is connected with vacuum extractor.
3. compressing dry granulation machine according to claim 1 or 2, is characterized in that, described broken granulating mechanism comprises blade type breaker and whole grain device, and described whole grain device comprises cylinder and is fixed on the axial blade on cylinder, is provided with board-like sieve outside cylinder.
4. compressing dry granulation machine according to claim 3, it is characterized in that, described dancer and fixing roller surface are provided with the straight burr of arc.
5. compressing dry granulation machine according to claim 4, it is characterized in that, described dancer and stationary roll inner hollow, be connected with cooling device.
6. compressing dry granulation machine according to claim 5, is characterized in that, described tablet press mechanism outside is provided with transparent cloche.
7. compressing dry granulation machine according to claim 6, it is characterized in that, described producer agency is single-punch tablet press, comprise upper plunger, middle mould and lower plunger, described upper plunger is arranged in above mould, lower plunger is arranged in below mould, the bottom of upper plunger, the upper end of lower plunger all can insert in nib.
8. compressing dry granulation machine according to claim 7, it is characterized in that, described producer agency bottom is provided with wheel, and wheel is positioned at slideway.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201420839502.9U CN204354514U (en) | 2014-12-26 | 2014-12-26 | A kind of compressing dry granulation machine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN201420839502.9U CN204354514U (en) | 2014-12-26 | 2014-12-26 | A kind of compressing dry granulation machine |
Publications (1)
Publication Number | Publication Date |
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CN204354514U true CN204354514U (en) | 2015-05-27 |
Family
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Family Applications (1)
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CN201420839502.9U Expired - Fee Related CN204354514U (en) | 2014-12-26 | 2014-12-26 | A kind of compressing dry granulation machine |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106262989A (en) * | 2016-08-19 | 2017-01-04 | 天津春发生物科技集团有限公司 | A kind of microcapsule method preparing prolongation powder body essence shelf life |
CN109353055A (en) * | 2018-11-23 | 2019-02-19 | 胡成兵 | Suppress the upper magazine of Chinese medicine and the prepared slices of Chinese crude drugs |
CN110143007A (en) * | 2019-05-16 | 2019-08-20 | 广州浩胜弘裕机械设备有限公司 | A kind of small rolling-printing machine |
-
2014
- 2014-12-26 CN CN201420839502.9U patent/CN204354514U/en not_active Expired - Fee Related
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106262989A (en) * | 2016-08-19 | 2017-01-04 | 天津春发生物科技集团有限公司 | A kind of microcapsule method preparing prolongation powder body essence shelf life |
CN109353055A (en) * | 2018-11-23 | 2019-02-19 | 胡成兵 | Suppress the upper magazine of Chinese medicine and the prepared slices of Chinese crude drugs |
CN110143007A (en) * | 2019-05-16 | 2019-08-20 | 广州浩胜弘裕机械设备有限公司 | A kind of small rolling-printing machine |
CN110143007B (en) * | 2019-05-16 | 2024-01-02 | 广州浩胜弘裕机械设备有限公司 | Small roll printing machine |
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Date | Code | Title | Description |
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C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20150527 |
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CF01 | Termination of patent right due to non-payment of annual fee |