CN204008676U - The full-automatic sample introduction mechanism of a kind of flow cytometer - Google Patents

The full-automatic sample introduction mechanism of a kind of flow cytometer Download PDF

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Publication number
CN204008676U
CN204008676U CN201420269279.9U CN201420269279U CN204008676U CN 204008676 U CN204008676 U CN 204008676U CN 201420269279 U CN201420269279 U CN 201420269279U CN 204008676 U CN204008676 U CN 204008676U
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sampling probe
rotating disc
flow cytometer
driving mechanism
full
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CN201420269279.9U
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蔡春午
李藏珍
李爱国
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Suzhou Rihe Technology Co Ltd
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Suzhou Rihe Technology Co Ltd
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Abstract

The utility model discloses the full-automatic sample introduction mechanism of a kind of flow cytometer, comprise the rotating disc that is radially distributed with some test tube mounting holes, be located at X on rotating disc one side fixed head to driving mechanism, and the sampling probe being connected to driving mechanism with X and Z-direction driving mechanism, X comprises that to driving mechanism the X being located on fixed head is to slide rail, be located at X to the sampling probe drive plate on slide rail, and for driving sampling probe drive plate to do the steering wheel bar-link drive of horizontal reciprocating movement along X to slide rail, Z-direction driving mechanism connects rotating disc by web joint simultaneously base driven rotary dish do the vertical to-and-fro movement of Z-direction, and web joint is connected with base by the rotary extension axle radially arranging along rotating disc, the X that employing is located on fixed head drives the sampling probe of being located on sampling probe drive plate to do horizontal reciprocating movement along X to slide rail to slide rail and steering wheel bar-link drive, not only simple in structure, and it is little to take up room, sampling probe tangential movement is also more stable.

Description

The full-automatic sample introduction mechanism of a kind of flow cytometer
Technical field
the utility model relates to a kind of sample introduction mechanism, especially relates to the full-automatic sample introduction mechanism of a kind of flow cytometer.
Background technology
flow cytometer (Flow cytometry) is the device that cell is carried out to automatic analysis and sorting.The a series of important biophysics of the cell dispersion that it can Quick Measurement, storage, demonstration float on a liquid, the characteristic parameter of biological chemistry aspect, and can the cell subsets of specifying therefrom be sorted out according to the parameter scope of preliminary election.
in prior art, flow cytometer has an important step to sample link before measuring, for the sample introduction mechanism of flow cytometer of the prior art, adopt drive motor to drive sampling probe to sample, not only increasing flow cytometer entirety takes up room, and adopt drive motor directly to drive, easily cause sampling probe motion unstable, sampling precision is low, simultaneously because flow cytometer is to sample from test tube, and the test tube bore of available technology adopting is generally narrower, in the time extracting liquid to be detected, cannot add rabbling mechanism, cause the data that detect inaccurate, for above-mentioned technical matters, prior art has also proposed a kind of stirring integrated sampling mechanism that samples, comprise a vibrating reed swinging, this vibrating reed is connected with sampling probe, drive sampling probe to swing or swing by vibrating reed, swaying direction is single, mixing effect is bad, and hunting range is not easy to control, be that sampling probe is easily encountered inboard wall of test tube in the process swinging, serious even breaking-up test tube and sampling probe.
Utility model content
the utility model object is: the full-automatic sample introduction mechanism of flow cytometer that a kind of simple in structure, take up room little and good stability are provided.
the technical solution of the utility model is: the full-automatic sample introduction mechanism of a kind of flow cytometer, comprise the rotating disc that is radially distributed with some test tube mounting holes, be located at X on described rotating disc one side fixed head to driving mechanism, and the sampling probe and the Z-direction driving mechanism that are connected to driving mechanism with described X, described X comprises that to driving mechanism the X being located on described fixed head is to slide rail, be located at described X to the sampling probe drive plate on slide rail, and for driving described sampling probe drive plate to do the steering wheel bar-link drive of horizontal reciprocating movement along X to slide rail, described Z-direction driving mechanism connects the base of described rotating disc by web joint and drives described rotating disc to do the vertical to-and-fro movement of Z-direction simultaneously, and described web joint is connected with described base by the rotary extension axle radially arranging along described rotating disc.
preferably, described steering wheel bar-link drive comprises the steering wheel of being located on described sampling probe drive plate, and the two-stage connecting rod that one end is connected with described fixed head, the other end is connected with described steering wheel.
preferably, described Z-direction driving mechanism comprises the Z-direction guide rail being fixedly connected with described sampling probe drive plate, and described web joint is connected and drives described rotating disc to do vertical to-and-fro movement along Z-direction guide rail with the slide block on described Z-direction guide rail.
preferably, also comprise sampling probe vibrating mechanism, described sampling probe vibrating mechanism comprises the holder being connected with described web joint, be located at the vibrating motor on described holder, the eccentric wheel apparatus being connected with described vibrating motor output terminal, and the oscillating plate being connected with described eccentric wheel apparatus by web member, described sampling probe one end is through described oscillating plate.
preferably, between described rotating disc and its base, be provided with damping elastic piece, this damping elastic piece is the effect of vibration for rotating disc for slowing down vibration plate.
preferably, described sampling probe vibrating mechanism also comprises the electromagnet of being located on described holder, and be located at the armature below described electromagnet, and described armature one end is set on described web member, and the top of described web member is connected with described eccentric wheel apparatus is detachable by bearing.
preferably, be connected with for keeping oscillating plate to do the elastic component of horizontal eccentric motion on described oscillating plate, the top of described elastic component is connected with described holder.
more preferably, described elastic component is spring.
the utility model has the advantages that:
1. the utility model adopts the X being located on fixed head to drive the sampling probe of being located on sampling probe drive plate to do horizontal reciprocating movement along X to slide rail to slide rail and steering wheel bar-link drive, not only simple in structure, and it is little to take up room, sampling probe tangential movement is also more stable;
2. the utility model is in the time that sampling probe inserts test tube sampling, adopt the eccentric wheel apparatus in sampling probe vibrating mechanism to drive oscillating plate to do eccentric motion, thereby drive further sampling probe to do eccentric motion, and stir invisible spectro testing liquid, mixing effect is better compared with prior art, thereby has further improved sampling precision;
3. the utility model adopts the sampling probe of sampling, agitating function one, when saving equipment cost, reduce the shared space of equipment, and adopt eccentric wheel apparatus be convenient to control sampling probe in vitro wall scope with interior motion, effectively prevent that in motion process, sampling probe touches test tube wall, even cause sampling probe or test tube wall breakage, be applicable to the narrower test tube stirring sampling of bore;
4. the utility model adopts electromagnet and armature cooperation to make sampling probe after stirring completes, have automatic reset function, and sampling probe, after stirring completes, is got back to initial position automatically, and then sampling;
5. the utility model adopts elastic component connection fixing base and oscillating plate, effectively prevents that sampling probe from tilting, and ensures that oscillating plate does eccentric motion in the horizontal direction.
Brief description of the drawings
below in conjunction with drawings and Examples, the utility model is further described:
fig. 1 is the front view of the full-automatic sample introduction mechanism of the utility model flow cytometer;
fig. 2 is the side view of the full-automatic sample introduction mechanism of the utility model flow cytometer;
fig. 3 the utility model X is to driving mechanism, Z-direction driving mechanism and sampling probe vibrating mechanism schematic diagram;
fig. 4 is the utility model sampling probe vibrating mechanism stereographic map;
fig. 5 is the utility model sampling probe vibrating mechanism vertical view;
fig. 6 is the A-A face cut-open view of the utility model Fig. 5;
fig. 7 is the B-B face cut-open view of the utility model Fig. 5;
wherein: 1 rotating disc, 2 fixed heads, 3 sampling probes, 4aX is to slide rail, 4b sampling probe drive plate, 4c-1 steering wheel, 4c-2 two-stage connecting rod, 5 web joints, 6 bases, 7 rotary extension axles, 8aZ direction guiding rail, 8b slide block, 9a holder, 9b vibrating motor, 9c eccentric wheel apparatus, 9d web member, 9e oscillating plate, 9f electromagnet, 9g armature, 9h bearing, 9i spring.
Embodiment
embodiment: shown in 7, the full-automatic sample introduction mechanism of a kind of flow cytometer, comprise the rotating disc 1 that is radially distributed with some test tube mounting holes, be located at X on rotating disc 1 one side fixed heads 2 to driving mechanism, and the sampling probe 3 being connected to driving mechanism with X and Z-direction driving mechanism, X comprises that to driving mechanism the X being located on fixed head 2 is to slide rail 4a, be located at X to the sampling probe drive plate 4b on slide rail 4a, and for driving sampling probe drive plate 4b to do the steering wheel bar-link drive of horizontal reciprocating movement along X to slide rail 4a, this steering wheel bar-link drive comprises the steering wheel 4c-1 being located on sampling probe drive plate 4b, and one end is connected with fixed head 2, the two-stage connecting rod 4c-2 that the other end is connected with steering wheel 4c-1, Z-direction driving mechanism connects rotating disc 1 by web joint 5 simultaneously base 6 driven rotary dish 1 do the vertical to-and-fro movement of Z-direction, this Z-direction driving mechanism comprises the Z-direction guide rail 8a being fixedly connected with sampling probe drive plate 4b, web joint 5 is connected with the slide block 8b on Z-direction guide rail 8a and driven rotary dish 1 does vertical to-and-fro movement along Z-direction guide rail 8a, and web joint 5 is connected with base 6 by the rotary extension axle 7 radially arranging along rotating disc 1, the utility model adopts the X being located on fixed head 2 to drive the sampling probe 3 of being located on sampling probe drive plate 4b to do horizontal reciprocating movement along X to slide rail 4a to slide rail 4a and steering wheel bar-link drive, not only simple in structure, and it is little to take up room, sampling probe 3 tangential movements are also more stable.
with reference to shown in Fig. 3 to 7, the full-automatic sample introduction mechanism of flow cytometer of the present utility model also comprises sampling probe vibrating mechanism, sampling probe vibrating mechanism comprises the holder 9a being connected with web joint 5, be located at the vibrating motor 9b on holder 9a, the eccentric wheel apparatus 9c being connected with vibrating motor 9b output terminal, and the oscillating plate 9e being connected with eccentric wheel apparatus 9c by web member 9d, sampling probe 3 one end are through oscillating plate 9e, in the time that sampling probe 3 inserts test tube sampling, adopt the eccentric wheel apparatus 9c in sampling probe vibrating mechanism to drive oscillating plate 9e to do eccentric motion, thereby drive further sampling probe 3 to do eccentric motion, and stir invisible spectro testing liquid, mixing effect is better compared with prior art, thereby further improve sampling precision, adopt sampling simultaneously, the sampling probe of agitating function one, when saving equipment cost, reduce the shared space of equipment, and adopt eccentric wheel apparatus 9c be convenient to control sampling probe 3 in vitro wall scope with interior motion, effectively prevent that in motion process, sampling probe 3 touches test tube wall, even cause sampling probe 3 or test tube wall breakage, be applicable to the narrower test tube stirring sampling of bore, this sampling probe vibrating mechanism also comprises the electromagnet 9f being located on holder 9a, and be located at the armature 9g of electromagnet 9f below, armature 9g one end is set on web member 9d, the top of this web member 9d is connected with eccentric wheel apparatus 9c is detachable by bearing 9h, the utility model adopts electromagnet 9f and armature 9g cooperation to make sampling probe 3 after stirring completes, have automatic reset function, be sampling probe 3 after stirring completes, automatically get back to initial position, and then sampling, between rotating disc 1 and its base 6, be provided with damping elastic piece (not drawing on figure) simultaneously, this damping elastic piece is the effect of vibration for rotating disc 1 for slowing down vibration plate 9e, on this oscillating plate 9e, be connected with for keeping oscillating plate 9e to be the spring 9i of horizontal eccentric motion, the top of described spring 9i is connected with described holder 9a, adopt spring 9i connection fixing base 9a and oscillating plate 9e, effectively prevent that sampling probe 3 from tilting, ensure that oscillating plate 9e does eccentric motion in the horizontal direction.
above-described embodiment is only explanation technical conceive of the present utility model and feature, and its object is to allow person skilled in the art can understand content of the present utility model and implement according to this, can not limit protection domain of the present utility model with this.All equivalences of doing according to the utility model Spirit Essence change or modify, within all should being encompassed in protection domain of the present utility model.

Claims (8)

1. the full-automatic sample introduction mechanism of flow cytometer, comprise the rotating disc (1) that is radially distributed with some test tube mounting holes, be located at X on described rotating disc (1) one side fixed head (2) to driving mechanism, and the sampling probe (3) and the Z-direction driving mechanism that are connected to driving mechanism with described X, it is characterized in that, described X comprises that to driving mechanism the X being located on described fixed head (2) is to slide rail (4a), be located at described X to the sampling probe drive plate (4b) on slide rail (4a), and along X to slide rail, (4a) does the steering wheel bar-link drive of horizontal reciprocating movement for driving described sampling probe drive plate (4b), described Z-direction driving mechanism is connected the base (6) of described rotating disc (1) and is driven described rotating disc (5) to do the vertical to-and-fro movement of Z-direction by web joint (5) simultaneously, and described web joint (5) is connected with described base (6) by the rotary extension axle (7) radially arranging along described rotating disc (1).
2. the full-automatic sample introduction mechanism of flow cytometer according to claim 1, it is characterized in that, described steering wheel bar-link drive comprises the steering wheel (4c-1) of being located on described sampling probe drive plate (4b), and the two-stage connecting rod (4c-2) that one end is connected with described fixed head (2), the other end is connected with described steering wheel (4c-1).
3. the full-automatic sample introduction mechanism of flow cytometer according to claim 1, it is characterized in that, described Z-direction driving mechanism comprises the Z-direction guide rail (8a) being fixedly connected with described sampling probe drive plate (4b), and described web joint (5) is connected with the slide block (8b) on described Z-direction guide rail (8a) and drives described rotating disc (1) to do vertical to-and-fro movement along Z-direction guide rail (8a).
4. the full-automatic sample introduction mechanism of flow cytometer according to claim 1, it is characterized in that, also comprise sampling probe vibrating mechanism, described sampling probe vibrating mechanism comprises the holder (9a) being connected with described web joint (5), be located at the vibrating motor (9b) on described holder (9a), the eccentric wheel apparatus (9c) being connected with described vibrating motor (9b) output terminal, and the oscillating plate (9e) being connected with described eccentric wheel apparatus (9c) by web member (9d), described sampling probe (3) one end is through described oscillating plate (9e).
5. the full-automatic sample introduction mechanism of flow cytometer according to claim 4, is characterized in that, between described rotating disc (1) and its base (6), is provided with damping elastic piece.
6. the full-automatic sample introduction mechanism of flow cytometer according to claim 4, it is characterized in that, described sampling probe vibrating mechanism also comprises the electromagnet (9f) of being located on described holder (9a), and be located at the armature (9g) of described electromagnet (9f) below, it is upper that described armature (9g) one end is set in described web member (9d), and the top of described web member (9d) is by bearing (9h) and detachable connection of described eccentric wheel apparatus (9c).
7. the full-automatic sample introduction mechanism of flow cytometer according to claim 4, it is characterized in that, on described oscillating plate (9e), be connected with for keeping oscillating plate (9e) to do the elastic component of horizontal eccentric motion, the top of described elastic component is connected with described holder (9a).
8. the full-automatic sample introduction mechanism of flow cytometer according to claim 7, is characterized in that, described elastic component is spring (9i).
CN201420269279.9U 2014-05-26 2014-05-26 The full-automatic sample introduction mechanism of a kind of flow cytometer Active CN204008676U (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105717036A (en) * 2016-04-29 2016-06-29 安徽师范大学 Magnetic stirring type flow cytometry flowing chamber
CN108646009A (en) * 2018-03-26 2018-10-12 潍坊科技学院 A kind of multifunctional examining experiment device when blood sampling and its method of inspection
CN109781609A (en) * 2018-12-31 2019-05-21 苏州朗如精密机械科技有限公司 A kind of hit impact protection formula sampler of stream type cell analyzer

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105717036A (en) * 2016-04-29 2016-06-29 安徽师范大学 Magnetic stirring type flow cytometry flowing chamber
CN105717036B (en) * 2016-04-29 2018-04-17 安徽师范大学 A kind of flow cytometer flow chamber of magnetic stirring
CN108646009A (en) * 2018-03-26 2018-10-12 潍坊科技学院 A kind of multifunctional examining experiment device when blood sampling and its method of inspection
CN109781609A (en) * 2018-12-31 2019-05-21 苏州朗如精密机械科技有限公司 A kind of hit impact protection formula sampler of stream type cell analyzer

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