CN208459417U - A kind of full-automatic sample introduction mechanism of flow cytometer - Google Patents

A kind of full-automatic sample introduction mechanism of flow cytometer Download PDF

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Publication number
CN208459417U
CN208459417U CN201821067233.3U CN201821067233U CN208459417U CN 208459417 U CN208459417 U CN 208459417U CN 201821067233 U CN201821067233 U CN 201821067233U CN 208459417 U CN208459417 U CN 208459417U
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base
flow cytometer
full
sample introduction
gear
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CN201821067233.3U
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黄金科
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Tianjin Keyi Linda Technology Co Ltd
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Tianjin Keyi Linda Technology Co Ltd
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Abstract

The utility model discloses a kind of full-automatic sample introduction mechanisms of flow cytometer, including base, shake spring, storage base, RF transmitter, hydraulic cylinder, air pump, probe tube, stepper motor, PLC control cabinet and infrared receiver, base upper end side is equipped with wall, wall upper end side is horizontally installed with rack gear, described stepper motor one end is sequentially connected with gear, the wheel and rack engagement connection, pinch wheels are installed on the upside of the rack gear, and pinch wheels and gear pass through connection axis connection, hydraulic cylinder is installed on the downside of the stepper motor, telescopic rod is sequentially connected on the downside of the hydraulic cylinder, described telescopic rod one end is equipped with attachment base, the attachment base lower end is equipped with probe tube, described attachment base one end is equipped with appendix, a kind of full-automatic sample introduction mechanism of flow cytometer of the utility model, it will be to be checked The reagent of survey is placed in sample tube, and automatic sampling detection, high degree of automation, convenient for sampling can be carried out by control probe tube.

Description

A kind of full-automatic sample introduction mechanism of flow cytometer
Technical field
The utility model relates to sample introduction mechanism technical field, specifically a kind of full-automatic sample introduction mechanism of flow cytometer.
Background technique
Flow cytometer (Flowcytometry) is the device that cell is automatically analyzed and sorted.It can be quick Feature in terms of measurement, storage, a series of important biophysics for showing the cell dispersion to float on a liquid, biochemistry Parameter, and specified cell subsets can therefrom be sorted out according to the parameter ranges of pre-selection.Most flow cytometries are one The instrument of kind of zero resolution, it can only measure such as total nucleic acid amount an of cell, the indexs such as total protein concentration, and cannot identify and The nucleic acid of a certain privileged site or the number of albumen measured.That is, its detail resolution is zero.Flow cytometer is main It is made of four parts.They are: flow chamber and liquid fluid system;Laser source and optical system;Photoelectric tube and detection system;Computer And analysis system.Flow cytometer has an important link to sample link before measurements.
Existing flow cytometer sample introduction mechanism technology has the following problems: the existing full-automatic sample introduction machine of flow cytometer Structure, the degree of automation is lower, and structure is complicated for Part Full Automatic sample introduction mechanism, easily breaks down, and service life is lower, and positions Inaccuracy be easy to cause sampling error.
Utility model content
The purpose of this utility model is to provide a kind of full-automatic sample introduction mechanisms of flow cytometer, to solve in the prior art The problem of.
To achieve the above object, the utility model provides the following technical solutions: a kind of full-automatic sample introduction machine of flow cytometer Structure, including base, vibration spring, storage base, RF transmitter, hydraulic cylinder, air pump, probe tube, stepper motor, PLC control Cabinet and infrared receiver, base upper end side are equipped with wall, and wall upper end side is horizontally installed with rack gear, institute It states stepper motor one end and is sequentially connected with gear, the wheel and rack engagement connection, the rack gear upside is equipped with pinch wheels, And pinch wheels and gear, by connection axis connection, the stepper motor downside is equipped with hydraulic cylinder, transmission on the downside of the hydraulic cylinder It is connected with telescopic rod, described telescopic rod one end is equipped with attachment base, and the attachment base lower end is equipped with probe tube, the attachment base One end is equipped with appendix, and appendix is connected to probe tube top, and described appendix one end is connected with air pump, on the base Middle side part opens up fluted, is equipped with storage base by shaking spring in the groove, the storage base downside is equipped with exciting Device, the storage base upside offer test tube jack, sample tube, the test tube jack side are inserted in the test tube jack Storage base on RF transmitter is installed, described attachment base one end is equipped with infrared receiver, and infrared receiver It can be correspondingly arranged straight down with RF transmitter, the wall side is equipped with PLC control cabinet.
Preferably, the wall side is equipped with monitor station, is equipped with RF transmitter on the upside of described monitor station one end.
Preferably, the vibration excitor is mounted in the middle part of groove, and is connected on the upside of vibration excitor by vibrating shaft and storage base bottom It connects.
Preferably, the rack gear both ends are equipped with postive stop baffle, and the rack gear is arranged in parallel with storage base.
Preferably, test tube jack there are five equidistantly being opened up inside the storage base, and rubber is installed on the inside of test tube jack Glue-line.
Compared with prior art, the utility model has the beneficial effects that reagent to be detected is placed on by the utility model In sample tube, pinpoint function can be realized by the RF transmitter and outer line receiver that are equipped with, and pass through Stepper motor, gear and rack gear engagement connection are able to carry out and move horizontally sampling, and structural principle is simple, by the air pump that is equipped with into Row extracts the reagent sample in sample tube, and can carry out automatic sampling detection, the degree of automation by control probe tube Height, convenient for sampling, there are five test tube jacks by equidistantly opening up inside storage base, can place five kinds of reagents simultaneously and be examined It surveys, and rubber layer is installed on the inside of test tube jack, can be improved the stability that sample tube is plugged in test tube jack.
Detailed description of the invention
Fig. 1 is the overall structure diagram of the utility model;
Fig. 2 is the storage base structure top view of the utility model.
Fig. 3 is the stepper motor and hydraulic cylinder attachment structure schematic diagram of the utility model.
In figure: 1, base;2, wall;3, groove;4, spring is shaken;5, storage base;6, sample tube;7, infrared ray emits Device;8, monitor station;9, rack gear;10, postive stop baffle;11, hydraulic cylinder;12, air pump;13, probe tube;14, vibration excitor;15, it shakes Axis;16, test tube jack;17, telescopic rod;18, stepper motor;19, gear;20, PLC control cabinet;21, pinch wheels;22, it connects Axis;23, appendix;24, attachment base;25, infrared receiver.
Specific embodiment
The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole Embodiment.Based on the embodiments of the present invention, those of ordinary skill in the art are without making creative work Every other embodiment obtained, fall within the protection scope of the utility model.
Please refer to Fig. 1-3, in the utility model embodiment, a kind of full-automatic sample introduction mechanism of flow cytometer, including base 1, spring 4, storage base 5, RF transmitter 7, hydraulic cylinder 11, air pump 12, probe tube 13, stepper motor 18, PLC control are shaken Cabinet 20 and infrared receiver 25,1 upper end side of base are equipped with wall 2, and 2 upper end side of wall is horizontally installed with rack gear 9, just It is able to carry out and is moved horizontally by gear 19 in stepper motor 18,18 one end of stepper motor is sequentially connected with gear 19, gear 19 Connection is engaged with rack gear 9, pinch wheels 21 is installed, and pinch wheels 21 and gear 19 are connected by connecting shaft 22 on the upside of rack gear 9, just Stability when improving stepper motor 18 and being movably walking is equipped with hydraulic cylinder 11,11 downside of hydraulic cylinder on the downside of stepper motor 18 It is sequentially connected with telescopic rod 17, moves up and down sampling convenient for driving probe tube 13,17 one end of telescopic rod is equipped with attachment base 24,24 lower end of attachment base is equipped with probe tube 13, and 24 one end of attachment base is equipped with appendix 23, and appendix 23 and probe tube 13 Top connection, 23 one end of appendix is connected with air pump 12, and convenient for the pick-and-place of reagent, middle side part offers groove 3 on base 1, recessed Storage base 5 is installed by shaking spring 4 in slot 3, vibration excitor 14 is installed on the downside of storage base 5, it can be to the examination in sample tube 6 Agent carries out concussion mixing, prevents agent precipitate from influencing sample detection effect, offers test tube jack 16, test tube on the upside of storage base 5 It is inserted with sample tube 6 in jack 16, RF transmitter 7, attachment base 24 are installed on the storage base 5 of 16 side of test tube jack One end is equipped with infrared receiver 25, and infrared receiver 25 can be correspondingly arranged straight down with RF transmitter 7, It is convenient for being accurately positioned, 2 side of wall is equipped with PLC control cabinet 20, is convenient for controlling, and 2 side of wall is equipped with detection Platform 8,8 one end of monitor station upside are equipped with RF transmitter 7, and vibration excitor 14 is mounted on 3 middle part of groove, and 14 upside of vibration excitor It is connect by vibrating shaft 15 with 5 bottom of storage base, 9 both ends of rack gear are equipped with postive stop baffle 10, and rack gear 9 is parallel with storage base 5 to be set It sets, the inside of storage base 5 equidistantly opens up that there are five test tube jacks 16, can place five kinds of reagents simultaneously and be detected, and test tube Rubber layer is installed on the inside of jack 16, can be improved the stability that sample tube 6 is plugged in test tube jack 16.
Working principle: reagent to be detected is placed in sample tube 6, by 18 driving hydraulic cylinder 11 of stepper motor by From left to right is horizontally moved, when RF transmitter 7 and the infrared receiver 25 straight down of 16 side of test tube jack PLC control cabinet 20 is passed to by signal to infrared receiver 25 when corresponding to, PLC control cabinet 20 stops stepper motor 18 is controlled Work, while the flexible telescopic rod 17 downwards of hydraulic cylinder 11 is controlled, probe tube 13 is inserted into the liquid level in sample tube 6 once, with Air pump 12, which is evacuated, afterwards sucks test solution in probe tube 13, and then hydraulic cylinder 11 drives probe tube 13 to move up, and passes through stepping electricity Machine 18 is moved to 8 top of monitor station, and when being moved to surface, air pump 12 blasts gas into probe tube 13, and test solution has been squeezed out At single sample detection, the RF transmitter 7 of 13 side of probe tube is closed after the completion of sampling, is sequentially completed the sampling of remaining test tube Detection, high degree of automation, convenient for sampling, there are five test tube jacks 16 by equidistantly opening up inside storage base, can Five kinds of reagents are placed simultaneously to be detected, and rubber layer is installed on the inside of test tube jack 16, be can be improved sample tube and are plugged on Stability in test tube jack 16.
It is obvious to a person skilled in the art that the present invention is not limited to the details of the above exemplary embodiments, and And without departing substantially from the spirit or essential attributes of the utility model, it can realize that this is practical new in other specific forms Type.Therefore, in all respects, the present embodiments are to be considered as illustrative and not restrictive, this is practical new The range of type is indicated by the appended claims rather than the foregoing description, it is intended that containing for the equivalent requirements of the claims will be fallen in All changes in justice and range are embraced therein.It should not treat any reference in the claims as limiting Related claim.

Claims (5)

1. a kind of full-automatic sample introduction mechanism of flow cytometer, including base (1), vibration spring (4), storage base (5), infrared ray hair Emitter (7), hydraulic cylinder (11), air pump (12), probe tube (13), stepper motor (18), PLC control cabinet (20) and infrared receiver Device (25), it is characterised in that: base (1) the upper end side is equipped with wall (2), and wall (2) the upper end side is laterally pacified Equipped with rack gear (9), described stepper motor (18) one end is sequentially connected with gear (19), and the gear (19) is engaged with rack gear (9) Connection, rack gear (9) upside is equipped with pinch wheels (21), and pinch wheels (21) and gear (19) are connected by connecting shaft (22) It connects, is equipped with hydraulic cylinder (11) on the downside of the stepper motor (18), be sequentially connected with telescopic rod on the downside of the hydraulic cylinder (11) (17), described telescopic rod (17) one end is equipped with attachment base (24), and attachment base (24) lower end is equipped with probe tube (13), institute It states attachment base (24) one end to be equipped with appendix (23), and appendix (23) is connected to probe tube (13) top, the appendix (23) one end is connected with air pump (12), and middle side part offers groove (3) on the base (1), passes through vibration in the groove (3) Spring (4) is equipped with storage base (5), is equipped with vibration excitor (14) on the downside of the storage base (5), is opened on the upside of the storage base (5) Equipped with test tube jack (16), it is inserted with sample tube (6) in the test tube jack (16), the storage of test tube jack (16) side It is equipped on object seat (5) RF transmitter (7), described attachment base (24) one end is equipped with infrared receiver (25), and red Outer line receiver (25) is correspondingly arranged straight down with RF transmitter (7), and wall (2) side is equipped with PLC control Cabinet (20).
2. the full-automatic sample introduction mechanism of a kind of flow cytometer according to claim 1, it is characterised in that: the wall (2) Side is equipped with monitor station (8), is equipped with RF transmitter (7) on the upside of described monitor station (8) one end.
3. the full-automatic sample introduction mechanism of a kind of flow cytometer according to claim 1, it is characterised in that: the vibration excitor (14) it is mounted in the middle part of groove (3), and is connect by vibrating shaft (15) with storage base (5) bottom on the upside of vibration excitor (14).
4. the full-automatic sample introduction mechanism of a kind of flow cytometer according to claim 1, it is characterised in that: the rack gear (9) Both ends are equipped with postive stop baffle (10), and the rack gear (9) is arranged in parallel with storage base (5).
5. the full-automatic sample introduction mechanism of a kind of flow cytometer according to claim 1, it is characterised in that: the storage base (5) there are five equidistantly opening up inside test tube jack (16), and rubber layer is installed on the inside of test tube jack (16).
CN201821067233.3U 2018-07-06 2018-07-06 A kind of full-automatic sample introduction mechanism of flow cytometer Active CN208459417U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201821067233.3U CN208459417U (en) 2018-07-06 2018-07-06 A kind of full-automatic sample introduction mechanism of flow cytometer

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Application Number Priority Date Filing Date Title
CN201821067233.3U CN208459417U (en) 2018-07-06 2018-07-06 A kind of full-automatic sample introduction mechanism of flow cytometer

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111521547A (en) * 2020-05-13 2020-08-11 洹仪科技(上海)有限公司 Particle analyzing and sorting device and method
CN112629959A (en) * 2020-12-31 2021-04-09 北京瑞升特科技有限公司 Pneumatic stirring sampling device for sampler
CN113109583A (en) * 2021-04-13 2021-07-13 亚能生物技术(深圳)有限公司 Sample test tube processing device of flow cytometer
CN113624911A (en) * 2021-08-16 2021-11-09 哈尔滨放飞科技有限公司 High-efficient detection device of soil for environmental detection
CN116555029A (en) * 2023-05-16 2023-08-08 宁波宇泰医疗器械有限公司 Stem cell culture system with high survival rate

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111521547A (en) * 2020-05-13 2020-08-11 洹仪科技(上海)有限公司 Particle analyzing and sorting device and method
CN112629959A (en) * 2020-12-31 2021-04-09 北京瑞升特科技有限公司 Pneumatic stirring sampling device for sampler
CN113109583A (en) * 2021-04-13 2021-07-13 亚能生物技术(深圳)有限公司 Sample test tube processing device of flow cytometer
CN113109583B (en) * 2021-04-13 2024-02-13 亚能生物技术(深圳)有限公司 Flow cytometer sample test tube processing device
CN113624911A (en) * 2021-08-16 2021-11-09 哈尔滨放飞科技有限公司 High-efficient detection device of soil for environmental detection
CN113624911B (en) * 2021-08-16 2023-12-29 安徽环科检测中心有限公司 Soil high-efficiency detection device for environment detection
CN116555029A (en) * 2023-05-16 2023-08-08 宁波宇泰医疗器械有限公司 Stem cell culture system with high survival rate

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