CN203855590U - Shaking stirring type biological cell culture device - Google Patents
Shaking stirring type biological cell culture device Download PDFInfo
- Publication number
- CN203855590U CN203855590U CN201420295108.3U CN201420295108U CN203855590U CN 203855590 U CN203855590 U CN 203855590U CN 201420295108 U CN201420295108 U CN 201420295108U CN 203855590 U CN203855590 U CN 203855590U
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- Prior art keywords
- stirring
- tank body
- cultivation tank
- culture apparatus
- biomass cells
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Abstract
The utility model provides a shaking stirring type biological cell culture device which is characterized in that two arched tracks in parallel are arranged at the bottom of the culture tank; straight support plates are respectively arranged at two ends of each arched track; a steel wire rope is connected with the lower part of each straight support plate; the steel wire rope is connected with a rotating barrel; the rotating barrel is connected with a driving device. The biological cell culture device adopts a material shaking stirring mode, the shearing damage function of an inserting type stirring to biological cells is avoided, and meanwhile the biological cell culture device is simple in structure, convenient to maintain and wide in application range.
Description
Technical field:
The utility model relates to one and waves stirring-type biomass cells culture apparatus, belongs to biological plant technical field.
Background technology:
Express and produce all kinds of diagnosis and treatment monoclonal antibody by zooblast vitro culture, vaccine, the biological activity proteins such as somatomedin have market application foreground very widely.Therefore, be used for large scale and high density to cultivate the biomass cells reactor of zooblast, just become most important equipment in biotechnological pharmaceutics industry.It has determined product cost, industrial scale and the product category of biotechnological pharmaceutics enterprise to a great extent.Existing reactor adopts the mechanical stirring mode of inserting in tank body to promote flowing of liquid, the problem of the microbial contamination that in work, whipping appts structure and lubricating substance thereof often bring, living contaminants stirs lubricated situation incidence of bringing miscellaneous bacteria into high, once will cause necrocytosis.
Summary of the invention:
The purpose of this utility model is to provide one to wave stirring-type biomass cells culture apparatus for the problem of above-mentioned existence, the mode of batch mixing is waved in employing, has avoided insert to stir the shear fracture effect to biomass cells, simultaneously simple in structure, be convenient to safeguard, applied widely.
Above-mentioned object realizes by following technical scheme:
Wave stirring-type biomass cells culture apparatus, comprise cultivation tank body, described cultivation tank base is provided with two arc-shaped rails that intersect vertically, the two ends of the arc-shaped rail described in every arrange respectively straight fagging, described straight fagging bottom connects steel cable, described wireline connection of rotating cylinder, described rotary drum connecting drive device.
The described stirring-type biomass cells culture apparatus that waves, described drive unit comprises drive-motor, and described drive-motor connects described rotary drum by step-down gear, and described drive-motor connects positive and negative rotating controller.
The described stirring-type biomass cells culture apparatus that waves, the bottom of described straight fagging is provided with elastic shock attenuation seat, and described elastic shock attenuation seat comprises the spring being connected with straight fagging and is positioned at the cushion block being connected with spring of spring bottom.
The described stirring-type biomass cells culture apparatus that waves, described cultivation tank body top is provided with functional cover, described functional cover comprises the cover plate being connected with described cultivation tank body, is provided with airway, dissolved oxygen rate tester, thermometer through described cover plate on described cover plate.
The described stirring-type biomass cells culture apparatus that waves, the bottom, the inside of described cultivation tank body is provided with cone-shaped body, and the aspect ratio of described cultivation tank body is between 0.35-0.45.
Beneficial effect:
1. the utility model hockets by the forward and reverse of rotary drum, drive wireline to tighten up or decontrol, like this under the pulling of wireline, cultivating tank body left-right and front-back tilts to rock, the culture of the inside plays the effect of mix and blend, avoid insert to stir the large negative impact of seriously polluted and shear fracture bringing, and simple in structure, applied widely.
If 2. the aspect ratio of the stirring tank body of this rocking type is excessive, easily cause stirring inhomogeneous, therefore find through test of many times research, cultivate aspect ratio mixing effect the best between 0.35-0.45 of tank body.
3. the utility model is provided with cone-shaped body in tank base, and in the process of rocking at tank body, cone-shaped body can play the effect of stirring better, and reactive force temperature, can not produce large damage to cell.
Brief description of the drawings:
Fig. 1 is structural representation of the present utility model.
In figure: 1, cultivate tank body; 2, arc-shaped rail; 3, straight fagging; 4, wireline; 5, rotary drum; 6, drive-motor; 7, step-down gear; 8, positive and negative rotating controller; 9, spring; 10, cushion block; 11, cover plate; 12, airway; 13, dissolved oxygen rate tester; 14, thermometer.
Embodiment:
As shown in Figure 1: the present embodiment wave stirring-type biomass cells culture apparatus, comprise and cultivate tank body 1, described cultivation tank base is provided with two arc-shaped rails that intersect vertically 2, the two ends of the arc-shaped rail described in every arrange respectively straight fagging 3, described straight fagging bottom connects steel cable 4, described wireline connection of rotating cylinder 5, described rotary drum connecting drive device.It should be noted, in actual control process, in the time that the rotary drum of same track one side tightens up wireline, the rotary drum of opposite side should loosen wireline with same speed, so just can play the object of rocking stirring, if the rotary drum of same track both sides tightens up wireline or loosens wireline simultaneously simultaneously, not reach the object of rocking stirring.
In the present embodiment, described drive unit comprises drive-motor 6, and described drive-motor connects described rotary drum by step-down gear 7, and described drive-motor connects positive and negative rotating controller 8.
In the present embodiment, the bottom of described straight fagging is provided with elastic shock attenuation seat, and described elastic shock attenuation seat comprises the spring 9 being connected with straight fagging and the cushion block being connected with spring 10 that is positioned at spring bottom.
In the present embodiment, described cultivation tank body top is provided with functional cover, and described functional cover comprises the cover plate 11 being connected with described cultivation tank body, is provided with airway 12, dissolved oxygen rate tester 13, thermometer 14 through described cover plate on described cover plate.
In the present embodiment, the bottom, the inside of described cultivation tank body is provided with cone-shaped body, and the aspect ratio of described cultivation tank body is between 0.35-0.45.
The disclosed technique means of the utility model scheme is not limited only to the disclosed technique means of above-mentioned technique means, also comprises by above technical characterictic and is equal to the technical scheme that replacement forms.Unaccomplished matter of the present utility model, belongs to those skilled in the art's common practise.
Claims (5)
1. one kind is waved stirring-type biomass cells culture apparatus, comprise cultivation tank body, it is characterized in that: described cultivation tank base is provided with two arc-shaped rails that intersect vertically, the two ends of the arc-shaped rail described in every arrange respectively straight fagging, described straight fagging bottom connects steel cable, described wireline connection of rotating cylinder, described rotary drum connecting drive device.
2. the stirring-type biomass cells culture apparatus that waves according to claim 1, it is characterized in that: described drive unit comprises drive-motor, described drive-motor connects described rotary drum by step-down gear, and described drive-motor connects positive and negative rotating controller.
3. the stirring-type biomass cells culture apparatus that waves according to claim 1 and 2, it is characterized in that: the bottom of described straight fagging is provided with elastic shock attenuation seat, described elastic shock attenuation seat comprises the spring being connected with straight fagging and is positioned at the cushion block being connected with spring of spring bottom.
4. the stirring-type biomass cells culture apparatus that waves according to claim 1 and 2, it is characterized in that: described cultivation tank body top is provided with functional cover, described functional cover comprises the cover plate being connected with described cultivation tank body, is provided with airway, dissolved oxygen rate tester, thermometer through described cover plate on described cover plate.
5. the stirring-type biomass cells culture apparatus that waves according to claim 1 and 2, is characterized in that: the bottom, the inside of described cultivation tank body is provided with cone-shaped body, and the aspect ratio of described cultivation tank body is between 0.35-0.45.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420295108.3U CN203855590U (en) | 2014-05-29 | 2014-05-29 | Shaking stirring type biological cell culture device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420295108.3U CN203855590U (en) | 2014-05-29 | 2014-05-29 | Shaking stirring type biological cell culture device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203855590U true CN203855590U (en) | 2014-10-01 |
Family
ID=51605457
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420295108.3U Expired - Fee Related CN203855590U (en) | 2014-05-29 | 2014-05-29 | Shaking stirring type biological cell culture device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203855590U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105087364A (en) * | 2015-08-31 | 2015-11-25 | 太仓百诺纳米科技有限公司 | Anaerobic treatment device and system |
| CN108048319A (en) * | 2017-12-22 | 2018-05-18 | 广州汉腾生物科技有限公司 | Cell culture reactor |
-
2014
- 2014-05-29 CN CN201420295108.3U patent/CN203855590U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105087364A (en) * | 2015-08-31 | 2015-11-25 | 太仓百诺纳米科技有限公司 | Anaerobic treatment device and system |
| CN105087364B (en) * | 2015-08-31 | 2018-05-22 | 太仓昊恒纳米科技有限公司 | A kind of anaerobic processing device and system |
| CN108048319A (en) * | 2017-12-22 | 2018-05-18 | 广州汉腾生物科技有限公司 | Cell culture reactor |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20141001 Termination date: 20150529 |
|
| EXPY | Termination of patent right or utility model |