CN203658373U - Magnetic separation device - Google Patents
Magnetic separation device Download PDFInfo
- Publication number
- CN203658373U CN203658373U CN201320829645.7U CN201320829645U CN203658373U CN 203658373 U CN203658373 U CN 203658373U CN 201320829645 U CN201320829645 U CN 201320829645U CN 203658373 U CN203658373 U CN 203658373U
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- CN
- China
- Prior art keywords
- cup
- magnetic
- shaped cavity
- adsorbed
- magnetic beads
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000007885 magnetic separation Methods 0.000 title abstract description 5
- 238000006243 chemical reaction Methods 0.000 claims abstract description 32
- 239000004568 cement Substances 0.000 claims description 3
- 239000011324 bead Substances 0.000 abstract description 24
- 238000004140 cleaning Methods 0.000 abstract description 11
- 238000001179 sorption measurement Methods 0.000 abstract description 2
- 230000001376 precipitating effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 description 9
- 238000005516 engineering process Methods 0.000 description 6
- 239000000376 reactant Substances 0.000 description 5
- 238000003018 immunoassay Methods 0.000 description 4
- 238000004458 analytical method Methods 0.000 description 3
- 239000003153 chemical reaction reagent Substances 0.000 description 3
- 230000005540 biological transmission Effects 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
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- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The utility model provides a magnetic separation device. The magnetic separation device comprises a bracket, wherein the bracket is provided with a plurality of fixed positions; magnetic pieces are arranged at the fixed position; each magnetic piece is provided with a cup-shaped cavity; a reaction cup can be placed in the corresponding cup-shaped cavity; the bottom of each reaction cup is provided with a bulge for preventing magnetic beads from being absorbed away while being cleaned after precipitating to the middle of the bottom; the inner wall of each cup-shaped cavity is of a slope-shaped structure, and the bottom end of each cup-shaped cavity is narrower than the top end of the corresponding cup-shaped cavity; the part, inserted into each cup-shaped cavity, of the corresponding reaction cup is also provided with a slope-shaped surface matched with the corresponding slope-shaped structure. According to the slope-shaped surface, besides the contact areas of the magnetic beads are increased, an upward resistance force is further provided, so that the magnetic beads adsorbed on the inner walls of the reaction cups are prevented from falling to the bottoms of the cup, and the magnetic beads are adsorbed on the walls of the cups as much as possible. The whole bottom of each reaction cup is surrounded by the magnetic field of the corresponding magnetic piece, and the magnetic beads are adsorbed on the whole circle of the inner wall of the corresponding reaction cup instead of being only adsorbed on one side independently during the cleaning so that the adsorption strength of the magnetic beads is increased so as to ensure that the magnetic beads are not adsorbed away during the cleaning.
Description
Technical field
The utility model relates to a kind of magnetic separating device, and particularly a kind of magnetic separating device for Full-automatic chemiluminescence immunoassay analysis meter, belongs to biochemistry detection equipment technical field.
Background technology
Automatic chemiluminescence immunoassay technology is a complicated analytic process, this process mainly by add sample to reaction vessel (abbreviation application of sample), reagent adding, add chemiluminescent labels (being magnetic bead) to reaction vessel, control fluid temperature constant (incubation) in reaction vessel, to reactant carry out magnetic separation with cleaning (magnetic separates and cleans), add and start reagent to steps such as reaction vessel, measurement reactant are luminous, and the operation that these steps is connected in to a series of transmission reaction vessels of instrument forms.Whole operating process is mainly divided into the planar gesture of reaction vessel motion and adds the stereoscopic motion of sample, reagent, magnetic bead and data acquisition, transmission.
The development of Full-automatic chemiluminescence immunoassay analysis meter relates to many-sided high-tech technology such as electronics, machinery, optics, computer technology, biological chemistry, apparatus structure complexity, need huge R & D Cost early stage, the development of current domestic Related product is still in the starting stage, and in this instrument, related magnetic separating device also needs to research and develop better.
In the application of Full-automatic chemiluminescence immunoassay analysis meter, need to clean the reactant in reaction cup, in the process of cleaning, need a device that the magnetic bead in reaction cup is adsorbed on reaction cup inwall, prevent that magnetic bead is sucked away in cleaning process, to ensure the accuracy of test result, the prior art side magnetic original papers that adopt carry out magnetic bead absorption more, and the efficiency that this magnetic separates needs further to be improved.
Utility model content
The technical problems to be solved in the utility model is to provide a kind of magnetic separating device, this device is in the process of cleaning excess reactant, retain preferably that a part of reactant of being combined with magnetic bead, and ensure that the time of whole magnetic separation is short as much as possible, thereby ensure the accuracy of test result.
Specifically, magnetic separating device described in the utility model, comprise support, support is provided with several fixed bits, magnetic part is arranged on fixed bit, and magnetic part is provided with a cup-shaped cavity, and reaction cup can be put into cup-shaped cavity, be provided with a projection in reaction cup bottom, prevent that magnetic bead is sucked away in the middle of being deposited to bottom in cleaning.
Further, the inwall of described cup-shaped cavity is slope shape structure, and bottom is narrow compared with top, and the part that reaction cup is inserted cup-shaped cavity also has the slope shape face adapting with above-mentioned slope shape structure.This slope shape face, except increasing magnetic bead contact area, also provides a resistance upwards, at the bottom of stoping the magnetic bead being adsorbed on reaction cup inwall down to drop to glass, ensures that magnetic bead is adsorbed on wall of cup as much as possible.
Further, the bottom of magnetic part adopts plastic cement screw to be fixed on support.
Described reaction cup is surrounded by the magnetic field of magnetic part near the surrounding of bottom, in cleaning process, magnetic bead can be adsorbed on a whole circle inwall of reaction cup, instead of is only adsorbed onto separately in a side, increase the adsorption strength of magnetic bead, ensured that magnetic bead can not be sucked away in cleaning process.
Brief description of the drawings
Fig. 1 is the one-piece construction schematic diagram of the utility model embodiment;
Fig. 2 is the cut-open view of the utility model embodiment reaction cup and magnetic part assembling;
Wherein, 1 is that support, 2 is that reaction cup, 3 is that magnetic part, 20 is that projection, 21 is that slope shape face, 30 is that cup-shaped cavity, 31 is slope shape structure.
Embodiment
Below in conjunction with accompanying drawing, technical scheme described in the utility model is described further, object is for the public understands described technology contents better, and the not restriction to described technology contents.
As shown in Figure 1-2, magnetic separating device described in the utility model, comprise support 1, support 1 is provided with several fixed bits, magnetic part 3 is arranged on fixed bit, magnetic part 3 is provided with a cup-shaped cavity 30, reaction cup 2 can be put into cup-shaped cavity 30, be provided with a projection 20 in reaction cup bottom, prevent that magnetic bead is sucked away in the middle of being deposited to bottom in cleaning, the inwall of described cup-shaped cavity 30 is slope shape structure 31, bottom is narrow compared with top, the part that reaction cup 2 is inserted cup-shaped cavity 30 also has the slope shape face 21 adapting with above-mentioned slope shape structure 31, this slope shape face 21 is except increasing magnetic bead contact area, a resistance upwards is also provided, stop the magnetic bead being adsorbed on reaction cup 2 inwalls to fall down, further, the bottom of magnetic part adopts plastic cement screw to be fixed on support.
Magnetic separating device described in the utility model, simple and practical, described reaction cup is surrounded by the magnetic field of magnetic part near the surrounding of bottom, and magnetic bead can not be sucked away in cleaning process.
Should be clear and definite be; the above embodiments comprise word and accompanying drawing; it is only a specific embodiment of described technical scheme; in fact; all improvement and conversion of described technical scheme being carried out with identical or approximate principle; comprise shape, the size of each several part structure, the variation of material used, and the close element of function be equal to replacement, all within the utility model technical scheme required for protection.
Claims (3)
1. a magnetic separating device, is characterized in that: comprise support, support is provided with several fixed bits, and magnetic part is arranged on fixed bit, and magnetic part is provided with a cup-shaped cavity, and reaction cup can be put into cup-shaped cavity, is provided with a projection in reaction cup bottom.
2. magnetic separating device according to claim 1, is characterized in that: the inwall of described cup-shaped cavity is slope shape structure, and bottom is narrow compared with top, and the part that reaction cup is inserted cup-shaped cavity also has the slope shape face adapting with above-mentioned slope shape structure.
3. magnetic separating device according to claim 1 and 2, is characterized in that: the bottom of described magnetic part adopts plastic cement screw to be fixed on support.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320829645.7U CN203658373U (en) | 2013-12-16 | 2013-12-16 | Magnetic separation device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320829645.7U CN203658373U (en) | 2013-12-16 | 2013-12-16 | Magnetic separation device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203658373U true CN203658373U (en) | 2014-06-18 |
Family
ID=50924750
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201320829645.7U Expired - Lifetime CN203658373U (en) | 2013-12-16 | 2013-12-16 | Magnetic separation device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203658373U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110869130A (en) * | 2017-07-19 | 2020-03-06 | 美国安进公司 | Magnetically assisted separation device and related methods |
| CN111912975A (en) * | 2019-05-09 | 2020-11-10 | 深圳华迈兴微医疗科技有限公司 | Magnetic separation device and chemiluminescence immunoassay analyzer |
| CN116328945A (en) * | 2023-05-30 | 2023-06-27 | 天津喜诺生物医药有限公司 | Magnetic separation and warm bath device |
-
2013
- 2013-12-16 CN CN201320829645.7U patent/CN203658373U/en not_active Expired - Lifetime
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110869130A (en) * | 2017-07-19 | 2020-03-06 | 美国安进公司 | Magnetically assisted separation device and related methods |
| US11433402B2 (en) | 2017-07-19 | 2022-09-06 | Amgen Inc. | Magnetic assisted separation apparatuses and related methods |
| CN111912975A (en) * | 2019-05-09 | 2020-11-10 | 深圳华迈兴微医疗科技有限公司 | Magnetic separation device and chemiluminescence immunoassay analyzer |
| CN116328945A (en) * | 2023-05-30 | 2023-06-27 | 天津喜诺生物医药有限公司 | Magnetic separation and warm bath device |
| CN116328945B (en) * | 2023-05-30 | 2023-08-08 | 天津喜诺生物医药有限公司 | Magnetic separation and warm bath device |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C56 | Change in the name or address of the patentee | ||
| CP03 | Change of name, title or address |
Address after: Nanshan District Nanshan street Shenzhen city Guangdong province 518000 Xing Hai Lu Lai Shan Industrial Zone 5 1-4 Patentee after: SHENZHEN YHLO BIOTECH Co.,Ltd. Address before: 518000 Lai Lai Shan Industrial Zone, Xing Hai Road, Shenzhen, Nanshan District, Guangdong Patentee before: SHENZHEN YHLO BIOTECH Co.,Ltd. |
|
| CP02 | Change in the address of a patent holder | ||
| CP02 | Change in the address of a patent holder |
Address after: 518000 Shenzhen 1 Longgang biological technology plant 1, Baolong two road, Baolong street, Guangdong Patentee after: SHENZHEN YHLO BIOTECH Co.,Ltd. Address before: 518000 Guangdong, Shenzhen, Nanshan District Nanshan street, Xinghai Road, Li Shan Industrial Zone, 1-4 1-4 floors. Patentee before: SHENZHEN YHLO BIOTECH Co.,Ltd. |
|
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20140618 |