CN203011925U - Tissue chip used for screening immunohistochemstry of antibody - Google Patents

Abstract

The utility model relates to a tissue chip used for screening the immunohistochemstry of an antibody. The tissue chip comprises a glass slide, micro-tissue blocks, four small arrays and a record book, wherein the glass slide is provided with a plurality of array point micro-tissue blocks which form the four small arrays, three lines and four columns of micro-tissue blocks are arranged in the small arrays, dot matrixes on the glass slide are grouped into four small arrays, the tissue types of the small arrays are consistent, each small array is used for detecting one antibody, and one tissue chip can detect four antibodies. According to the tissue chip, small array area processing is conducted to the micro-tissue blocks in the tissue chip, and the micro-tissue blocks can be arranged in the small arrays according to certain sequence, thereby favorably improving the accuracy and the working efficiency of tissue chip production staff, and being more conducive to improving the efficiency of a researcher on observing the research result of the tissue chip.

Description

A kind of organization chip for the screening of antibody mediated immunity group

Technical field

The utility model relates to organization chip, is specially a kind of organization chip for the screening of antibody mediated immunity group.

Background technology

At present domestic and international organization chip, its tens of points are arranged on microslide down to hundreds of little tissue block forming array points, the horizontal longitudinal pitch uniformity of array point.There is certain defective in the organization chip of said structure in actual application: one, for the organization chip locality is carried out mark, generally the little tissue block on organization chip array a certain angle is lacked as processing, affected the integrality of organization chip integral body; They are two years old, whole little tissue blocks is integrated on a microslide with the pattern of horizontal longitudinal pitch uniformity, make when inserting sample paraffin organization core in making organization chip paraffin mass process, easily cause staff's visual fatigue, easily will organize core wrong plug position; They are three years old, the experimental result of organization chip is mainly observed by manually carrying out microscopically at present, be difficult to during observation certain the chip piece tissue in organization chip is quick and precisely located, cause when cutting into slices movement is slightly arranged, debugging repeatedly and calculating that the observer just need to cut into slices, in order to redefine the position of certain chip piece tissue, greatly increased researcher's non-productive work amount; Observe an organization chip, the researcher is felt exhausted can't bear, slightly not carefully the mistake that result of study is fastened one person's story upon another person will occur; Its four, on organization chip the record in site and determine very inconvenient.

The utility model content

The technical matters that the utility model solves is to provide a kind of organization chip for the screening of antibody mediated immunity group, to solve the shortcoming in the above-mentioned background technology.

The technical matters that the utility model solves realizes by the following technical solutions:

a kind of organization chip for the screening of antibody mediated immunity group, comprise microslide, little tissue block, little array and minute book, described microslide is provided with the little tissue block of a plurality of array points, described little tissue block consists of a plurality of little arrays, the quantity of described little array is four, in described little array, the line number of little tissue block is three row, columns is four row, on described microslide, dot matrix is divided into four little arrays, the types of organization of each little array is consistent, a kind of antibody of each little array detection, an organization chip can detect four kinds of antibody, the first row of each little array types of organization from left to right is successively: the human tonsil, human glioma, lymthoma, prostate cancer, the second row types of organization from left to right of each little array is successively: cervical carcinoma, oophoroma, breast cancer, kidney, the third line of each little array types of organization from left to right is successively: colon cancer, cancer of the stomach, liver cancer, lung cancer.

In the utility model, the left side of little array is provided with minute book.

Beneficial effect

The utility model carries out discharging according to a graded in little array subregion processing and little array to the little tissue block of organization chip, be conducive to improve accuracy and the work efficiency that organization chip is made the staff, more be conducive to improve the efficient of researcher's tissues observed chip research result.

Description of drawings

Fig. 1 is structural representation of the present utility model.

Embodiment

For technological means, creation characteristic that the utility model is realized, reach purpose and effect is easy to understand, below in conjunction with concrete diagram, further set forth the utility model.

referring to Fig. 1, a kind of structural representation of the organization chip for the screening of antibody mediated immunity group, a kind of organization chip for the screening of antibody mediated immunity group comprises microslide 1, little tissue block 2, little array 3 and minute book 4, described microslide 1 is provided with the little tissue block 2 of a plurality of array points, described little tissue block 2 consists of a plurality of little arrays 3, the quantity of described little array 3 is four, the line number of the interior little tissue block 2 of described little array 3 is three row, columns is four row, on described microslide 1, dot matrix is divided into four little arrays 3, the types of organization of each little array 3 is consistent, each little array 3 detects a kind of antibody, an organization chip can detect four kinds of antibody, and the first row of each little array 3 types of organization from left to right is successively: the human tonsil, human glioma, lymthoma, prostate cancer, the second row types of organization from left to right of each little array 3 is successively: cervical carcinoma, oophoroma, breast cancer, kidney, the third line of each little array 3 types of organization from left to right is successively: colon cancer, cancer of the stomach, liver cancer, lung cancer.

In the utility model, the left side of little array 3 is provided with minute book 4.

When making many sick organization chips of planting, can be with different sick organization arrangements of planting in different little arrays 3, perhaps be arranged in respectively the corresponding row or column of different little arrays 3, when making the tumour progression organization chip, the tissue specimen of the same internal organs different parts of same patient can be arranged to put into respectively three sites of little array 3 same row in turn, a little array 3 can comprise 5 patients' tissue specimen; Also the tissue specimen of the same internal organs different parts of same patient can be arranged respectively in turn put into little array 3 with five sites of delegation, a little array 3 can comprise 3 patients' tissue specimen, the little tissue block 2 of organization chip is carried out discharging according to a graded in little array 3 subregions processing and little array 3, be conducive to improve accuracy and the work efficiency that organization chip is made the staff, more be conducive to improve the efficient of researcher's tissues observed chip research result.

above demonstration and described ultimate principle of the present utility model and principal character and advantage of the present utility model, the technician of the industry should understand, the utility model is not restricted to the described embodiments, that describes in above-described embodiment and instructions just illustrates principle of the present utility model, under the prerequisite that does not break away from the utility model spirit and scope, the utility model also has various changes and modifications, these changes and improvements all fall in claimed the utility model scope, the claimed scope of the utility model is defined by appending claims and equivalent thereof.

Claims (2)

1. organization chip that is used for the screening of antibody mediated immunity group, comprise microslide, little tissue block, little array and minute book, it is characterized in that, described microslide is provided with the little tissue block of a plurality of array points, described little tissue block consists of a plurality of little arrays, the quantity of described little array is four, in described little array, the line number of little tissue block is three row, columns is four row, on described microslide, dot matrix divides four to be little array, the types of organization of each little array is consistent, a kind of antibody of each little array detection, an organization chip can detect four kinds of antibody, the first row of each little array types of organization from left to right is successively: the human tonsil, human glioma, lymthoma, prostate cancer, the second row types of organization from left to right of each little array is successively: cervical carcinoma, oophoroma, breast cancer, kidney, the third line of each little array types of organization from left to right is successively: colon cancer, cancer of the stomach, liver cancer, lung cancer.

2. a kind of organization chip for the screening of antibody mediated immunity group according to claim 1, is characterized in that, the left side of little array is provided with minute book.