CN202928961U - High-biosecurity point-of-care testing instrument based on image or photosensitive scanning - Google Patents
High-biosecurity point-of-care testing instrument based on image or photosensitive scanning Download PDFInfo
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- CN202928961U CN202928961U CN 201220593456 CN201220593456U CN202928961U CN 202928961 U CN202928961 U CN 202928961U CN 201220593456 CN201220593456 CN 201220593456 CN 201220593456 U CN201220593456 U CN 201220593456U CN 202928961 U CN202928961 U CN 202928961U
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Abstract
The utility model relates to a high-biosecurity point-of-care testing instrument based on an image or photosensitive scanning, and belongs to the technical field of reagent testing. The high-biosecurity point-of-care testing instrument based on the image or the photosensitive scanning comprises an image or photosensitive scanning device, a reagent placement platform and a data processing device, wherein an image scanning area of the image or photosensitive scanning device is downward; the reagent placement platform is positioned just below the image scanning area of the image or photosensitive scanning device; and the reagent placement platform is in a movable type, and an operator does not need to have contact with a testing reagent already added to a biological sample, so that the biosecurity is enhanced. According to the high-biosecurity POCT (Point Of Care Testing) instrument based on the image or photosensitive scanning, the scanning surface of an image or photosensitive scanning system downwards reads the information of the testing reagent, and the testing reagent is right side up, so that the biological sample is prevented from outflowing; and the reagent placement platform is in the movable type, and the operator does not need to have contact with the testing reagent containing the biological sample, so that the biosecurity protection in a working process is enhanced.
Description
Technical field
The utility model relates to a kind of high biological safety based on image or sensitization scanning and immediately detects (POCT) instrument, belongs to reagent detection technique field.
Background technology
Instant detect that (POCT) is easy because of it, characteristics fast, be widely used in domestic and international reagent detection technique field.Present instant detector device adopts camera or single photo-sensitive cell to come the information of acquisition testing reagent more, gathers area less, how can only carry out single reagent and detect.Though the external employing scanner that occurs gathers the pattern that image detects, but its scanning plane upwards, when therefore being used for the reagent detection, machine testing on ability after application of sample reagent has needed to react outside instrument and completed, otherwise when the reagent that has just added sample is reversed downward placement, not yet be absorbed completely biological sample in its well and can drop onto on the scanning interface, cause biological sample to pollute.Therefore, the maximum drawback of the detecting pattern that the conventional sweep interface makes progress is embodied in: 1) can not carry out single step and detect, need to react outside machine complete after machine testing on ability; 2) even if react outside machine and complete, detect reagent placements that need face down, still there is the risk of biological specimen pollution operating platform; 3) because of needs, the reagent upset is placed, the operator must contact the reagent that has contained biological sample, has increased the biological pollution risk.
Therefore, provide a kind of instant detection (POCT) instrument of high biological safety just to become the technical barrier that this technical field is badly in need of solution.
The utility model content
The purpose of this utility model is to overcome the defective that exists in prior art, provides a kind of high biological safety based on image or sensitization scanning immediately to detect (POCT) instrument.
For achieving the above object, the utility model is taked following technical scheme:
A kind of high biological safety instant detector device based on image or sensitization scanning, comprise image or sensitization scanister, reagent placement platform and data processing equipment, the image scanning district (scanning plane) of described image or sensitization scanister is downward, the reagent placement platform be positioned at image or sensitization scanister the image scanning district under.
Form airtight, lighttight environment between the image scanning district of image or sensitization scanister and reagent placement platform, to reach the request for utilization of scanning.Detection reagent faces up and is placed on the reagent placement platform, and therefore need not detection reagent is inverted can its information of scanning collection.This instant detector device utilizes image or sensitization scanning collection to detect the information of reagent; Operating personnel need not to contact the detection reagent that has added biological specimen, have improved biological safety.
Described reagent placement platform is portable drawer-type structure, places or pipette reagent to be detected when opening, the whole image scanning district of complete overlay image or sensitization scanister when closed.
Also be provided for placing the packaged type pallet of reagent to be detected in above-mentioned instant detector device, the packaged type pallet is positioned on the reagent placement platform.
Described packaged type pallet also can arrange one or more cartridge positions, is used for placing one or more reagent to be detected.Reagent is placed on pallet, and after adding biological specimen, the operator can need not to contact the detection reagent that contains biological specimen by pallet operation again.
Described image or sensitization scanister are various scanners, as flat bed scanner etc.
Described data processing equipment is computing machine and display or panel computer or single-chip microcomputer or based on other devices of Computer Organization Principles.
Instant detector device of the present utility model also can arrange printing equipment, as printer etc., directly detection information is printed on printer paper.
High biological safety instant detector device based on image or sensitization scanning of the present utility model can be designed to all-in-one, can automatically complete the detection of reagent.
Reagent to be detected is collaurum, latex or magnetic bead immunochromatography reagent or immunofluorescent reagent, obtains sample detection information by image after the scanning collection sample detection or induction light density or light intensity or color during detection.Sample to be tested is extensive, can be human or animal's body fluid, as blood, urine etc., also can be the cell or tissue sample.
The utility model has the advantage of:
(1) immediately detect (POCT) instrument according to the utility model based on the high biological safety of image or sensitization scanning; image or sensitization scanning system scanning plane read the information that detects reagent downwards; thereby detection reagent faces up and avoids biological sample to flow out; and the reagent placement platform is packaged type; the operator need not to contact the detection reagent that contains biological specimen, improves the bio-safety protection in the course of work.
(2) the utility model adopts image or sensitization scanning, and scanning area is stablized greatly, can realize that a plurality of reagent detect simultaneously, increases the high flux advantage of instrument.The more important thing is, the utility model has been broken the conventional downward pattern of article scanning plane that is scanned, downward by scanning plane in system, make detection reagent can keep facing up, compare with the conventional sweep pattern, after the reagent application of sample, directly machine internal reaction detection, both realized the single step detection, really embody the convenience of instant detection, avoided again contacting of biological sample and detection platform.In addition, the reagent placement platform is the packaged type pallet, makes the operator not need to contact the detection reagent that has contained biological sample in operating process again, has further improved the biological safety of native system.
(3) adopt instant detection (POCT) system that immediately detects the high biological safety of (POCT) instrument based on the high biological safety of image or sensitization scanning, can realize quantitatively or qualitative detection; Also can realize simultaneously the detection of a plurality of samples.
Below by the drawings and specific embodiments, the utility model is described further, but and does not mean that restriction to the utility model protection domain.
Description of drawings
Fig. 1 is the structural representation of the utility model instant detector device.
Fig. 2 is the side-looking structural representation of the utility model instant detector device.
Fig. 3 is the structural representation of facing of the utility model instant detector device.
Embodiment
As Figure 1-3, be that the utility model detects structural representation, side view and the front elevation of (POCT) instrument immediately based on the high biological safety of image or sensitization scanning.This instant detector device comprises scanner 1, reagent placement platform 2, computing machine and display 3, and the image scanning district (scanning plane) of scanner 1 is downward, reagent placement platform 2 be positioned at scanner 1 the image scanning district under.Scanner 1 is connected on computing machine, and computing machine and display 3 are data processing equipment, can also be panel computer, single-chip microcomputer or based on other devices of Computer Organization Principles.Form airtight, lighttight environment between the image scanning district of scanner 1 and reagent placement platform 2, to satisfy the condition of scanning.
Also be provided be used to the packaged type pallet 4 of placing reagent to be detected in this instant detector device, packaged type pallet 4 is positioned on reagent placement platform 2.Packaged type pallet 4 also can arrange one or more cartridges position 5, is illustrated in figure 1 as 5 cartridge positions 5, can place simultaneously and detect 5 reagent to be detected.Kit 9 is placed on the cartridge position 5 of pallet, after adding biological specimen, the operator can need not to contact the detection reagent that contains biological specimen by pallet operation again.Detection reagent faces up and is placed on reagent placement platform 2, and therefore need not detection reagent is inverted can its information of scanning collection.
Instant detector device of the present utility model also arranges printer 8, can directly detection information be printed on printer paper.
As Figure 1-3, instant detector device of the present utility model is integrated machine, computing machine and display 3, scanner 1, printer and reagent placement platform 2 etc. are become one, its top is computing machine and display 3, scanner 1 is positioned at the center section of whole instrument, one side of all-in-one is provided with printer paper outlet 6, and the bottom arranges power supply and switch 10, can automatically complete the detection of reagent.
Reagent to be detected is collaurum, latex or magnetic bead immunochromatography reagent or immunofluorescent reagent, obtains sample detection information by image after the scanning collection sample detection or induction light density or light intensity or color during detection.Sample to be tested is extensive, can be human or animal's body fluid, as blood, urine etc., also can be the cell or tissue sample.
Detection reagent in this detection system faces up, and therefore can realize directly dripping sample single step measuring ability; The tester clicks test button by sample adding device or after directly dripping biological specimen, and this system can automatically complete reagent and detect.Employing detects instant detection (POCT) system of the high biological safety of (POCT) instrument immediately based on the high biological safety of image or sensitization scanning, can realize quantitatively or qualitative detection; Also can realize simultaneously the detection of a plurality of samples.
Embodiment 1: the DDi in people's whole blood (or serum/plasma) quantitatively detects (colloidal gold method)
1) the instrument start runs to operation interface;
2) application of sample detects: 5 DDi immue quantitative detection reagent boxes (colloidal gold method) are torn packing be placed in the packaged type pallet 4 of instrument, corresponding 5 parts of whole blood DDi samples to be tested, get the cartridge position 5(well that 80 μ l whole bloods add corresponding kit for every part) after, pallet is pushed in the reactive tank of reagent placement platform 2 test button at clicking operation interface.
3) result output: instrument was completed detection automatically in the time of 15 minutes, occurred the quantitative testing result of 5 duplicate samples on instrument interface, and after input detected person information, saving result is clicked print button, prints testing result.
4) process discarded object: the operator takes out pallet, and the detection reagent that directly will react complete pours in the biologic garbage bucket and focuses on.
Embodiment 2: the DDi qualitative detection (colloidal gold method) in people's whole blood (or serum/plasma)
1) the instrument start runs to operation interface;
2) application of sample detects: 3 DDi qualitative detection kits (colloidal gold method) are torn packing be placed in the packaged type pallet 4 of instrument, corresponding 3 parts of plasma D-dimer content samples to be tested, get the cartridge position 5(well that 50 μ l plasma samples add corresponding kit for every part) after, pallet is pushed in the reactive tank of reagent placement platform 2 test button at clicking operation interface.
3) result output: instrument was completed detection automatically in the time of 15 minutes, occurred the testing result (showing negative or positive) of 5 duplicate samples on instrument interface, and after input detected person information, saving result is clicked print button, prints testing result.
4) process discarded object: the operator takes out pallet, and the detection reagent that directly will react complete pours in the biologic garbage bucket and focuses on.
Embodiment 3: the N-terminal brain natriuretic peptide/ in people's whole blood (or serum/plasma) quantitatively detects (immunofluorescence technique)
1) the instrument start runs to operation interface;
2) application of sample detects: 1 N-terminal brain natriuretic peptide/detection kit (immunofluorescence technique) is torn packing be placed in the packaged type pallet 4 of instrument, get the cartridge position 5(well that 80 μ l whole blood samples add kit) after, pallet is pushed in the reactive tank of reagent placement platform 2 test button at clicking operation interface.
3) result output: instrument was completed detection automatically in the time of 15 minutes, occurred quantitative testing result on instrument interface, and after input detected person information, saving result is clicked print button, prints testing result.
4) process discarded object: the operator takes out pallet, and the detection reagent that directly will react complete pours in the biologic garbage bucket and focuses on.
Adopt above-mentioned detection mode to detect DDi, with the detection mode that makes progress of scanning interface---be the kit application of sample after 15 minutes face down be placed on to detect on the scanning interface and compare, carried out altogether the detection of same batch of 40 parts of reagent, every group of 20 examples, two groups of result differences are without conspicuousness (p〉0.5), linearly dependent coefficient r=0.995, two kinds of detection modes are described, and height is consistent as a result.
Adopt above-mentioned detection mode to detect the N-terminal brain natriuretic peptide/, with the detection mode that makes progress of scanning interface---be the kit application of sample after 15 minutes face down be placed on to detect on the scanning interface and compare, carried out altogether the detection of same batch of 60 parts of reagent, every group of 30 examples, two groups of result differences are without conspicuousness (p〉0.5), linearly dependent coefficient r=0.997, two kinds of detection modes are described, and height is consistent as a result.
Claims (10)
1. high biological safety instant detector device based on image or sensitization scanning, it is characterized in that: comprise image or sensitization scanister, reagent placement platform and data processing equipment, the image scanning district of described image or sensitization scanister is downward, the reagent placement platform be positioned at image or sensitization scanister the image scanning district under.
2. the high biological safety instant detector device based on image or sensitization scanning according to claim 1, is characterized in that: light tight between the image scanning district of described image or sensitization scanister and reagent placement platform.
3. the high biological safety instant detector device based on image or sensitization scanning according to claim 2, it is characterized in that: described reagent placement platform is drawer-type structure.
4. the high biological safety instant detector device based on image or sensitization scanning according to claim 3, is characterized in that: comprise that also be used to the packaged type pallet of placing reagent to be detected, described packaged type pallet is positioned on the reagent placement platform.
5. the high biological safety instant detector device based on image or sensitization scanning according to claim 4, it is characterized in that: described packaged type pallet also arranges one or more cartridge position.
6. the high biological safety instant detector device based on image or sensitization scanning according to claim 1, it is characterized in that: described image or sensitization scanister are flat bed scanner.
7. the high biological safety instant detector device based on image or sensitization scanning according to claim 1, it is characterized in that: described data processing equipment is computing machine and display, or panel computer, or single-chip microcomputer.
8. the high biological safety instant detector device based on image or sensitization scanning according to claim 1, is characterized in that: also comprise printing equipment.
9. the high biological safety instant detector device based on image or sensitization scanning according to claim 1, it is characterized in that: described instant detector device is integrated machine.
10. the high biological safety instant detector device based on image or sensitization scanning according to claim 4, it is characterized in that: described reagent to be detected is collaurum, latex or magnetic bead immunochromatography reagent or immunofluorescent reagent.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220593456 CN202928961U (en) | 2012-10-10 | 2012-11-12 | High-biosecurity point-of-care testing instrument based on image or photosensitive scanning |
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| CN201210384893.5 | 2012-10-10 | ||
| CN201210384893 | 2012-10-10 | ||
| CN 201220593456 CN202928961U (en) | 2012-10-10 | 2012-11-12 | High-biosecurity point-of-care testing instrument based on image or photosensitive scanning |
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| CN202928961U true CN202928961U (en) | 2013-05-08 |
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| CN2012104493704A Pending CN102944560A (en) | 2012-10-10 | 2012-11-12 | High-biosecurity POCT (Point of Care Testing) instrument based on image or sensitizing scanning |
| CN 201220593456 Expired - Lifetime CN202928961U (en) | 2012-10-10 | 2012-11-12 | High-biosecurity point-of-care testing instrument based on image or photosensitive scanning |
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| CN2012104493704A Pending CN102944560A (en) | 2012-10-10 | 2012-11-12 | High-biosecurity POCT (Point of Care Testing) instrument based on image or sensitizing scanning |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102944560A (en) * | 2012-10-10 | 2013-02-27 | 武汉明德生物科技有限责任公司 | High-biosecurity POCT (Point of Care Testing) instrument based on image or sensitizing scanning |
| CN104865399A (en) * | 2015-05-15 | 2015-08-26 | 武汉明德生物科技股份有限公司 | Anti-stuck quantitative immunity analyzer convenient to clean |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106442975B (en) * | 2016-08-31 | 2018-07-20 | 湖北华大瑞尔科技有限公司 | A kind of colloidal gold detection method |
| CN106226237A (en) * | 2016-09-09 | 2016-12-14 | 复旦大学附属肿瘤医院 | Portable sample treatment go-cart and portable sample processing system |
| CN108982450A (en) * | 2018-07-24 | 2018-12-11 | 上海雄图生物科技有限公司 | A kind of food safety fluorescence immunoassay quantifies poct detection system |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| EP1565743B1 (en) * | 2002-11-27 | 2010-12-29 | 3M Innovative Properties Company | Loading and ejection systems for biological growth plate scanner |
| CN1773288A (en) * | 2004-11-09 | 2006-05-17 | 盛进生物工程(深圳)有限公司 | Sidestream analytic system and method |
| CN101551340B (en) * | 2009-05-07 | 2011-03-23 | 上海交通大学 | Gold spot quantitative determination optical device |
| CN102944560A (en) * | 2012-10-10 | 2013-02-27 | 武汉明德生物科技有限责任公司 | High-biosecurity POCT (Point of Care Testing) instrument based on image or sensitizing scanning |
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- 2012-11-12 CN CN2012104493704A patent/CN102944560A/en active Pending
- 2012-11-12 CN CN 201220593456 patent/CN202928961U/en not_active Expired - Lifetime
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102944560A (en) * | 2012-10-10 | 2013-02-27 | 武汉明德生物科技有限责任公司 | High-biosecurity POCT (Point of Care Testing) instrument based on image or sensitizing scanning |
| CN104865399A (en) * | 2015-05-15 | 2015-08-26 | 武汉明德生物科技股份有限公司 | Anti-stuck quantitative immunity analyzer convenient to clean |
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| CN102944560A (en) | 2013-02-27 |
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Legal Events
| Date | Code | Title | Description |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C56 | Change in the name or address of the patentee |
Owner name: WUHAN EASYDIAGNOSIS BIOMEDICAINE CO., LTD. Free format text: FORMER NAME: WUHAN EASYDIAGNOSIS BIOMEDICINE CO., LTD. |
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| CP01 | Change in the name or title of a patent holder |
Address after: Dongxin Road Northeast Technology Park of East Lake Development Zone 430074 Hubei city of Wuhan province No. 1 students Pioneering Park E Building 2 floor Patentee after: WUHAN EASYDIAGNOSIS BIOMEDICINE Co.,Ltd. Address before: Dongxin Road Northeast Technology Park of East Lake Development Zone 430074 Hubei city of Wuhan province No. 1 students Pioneering Park E Building 2 floor Patentee before: WUHAN EASYDIAGNOSIS BIOMEDICINE Co.,Ltd. |
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| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20130508 |