CN202376253U - Simple crush injury preparation device of spinal cord injury animal model - Google Patents
Simple crush injury preparation device of spinal cord injury animal model Download PDFInfo
- Publication number
- CN202376253U CN202376253U CN2011205277328U CN201120527732U CN202376253U CN 202376253 U CN202376253 U CN 202376253U CN 2011205277328 U CN2011205277328 U CN 2011205277328U CN 201120527732 U CN201120527732 U CN 201120527732U CN 202376253 U CN202376253 U CN 202376253U
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- spinal cord
- animal model
- crush injury
- preparation facilities
- simple type
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Abstract
The utility model provides a simple crush injury preparation device of a spinal cord injury animal model. The device comprises a lime fixing support, wherein each support arm is fixed at each of four corners of a positioning base plate; extrusion rotary screws pass through screw holes of the positioning base plate; and fastening screws are fixed on telescopic rods of the lime fixing support. The device has simplified experimental operation program, strong operability, good repeatability and high regulation, and facilitates development of crush injury animal model preparation of spinal cord injury basic researches.
Description
Technical field
This utility model relates to a kind of animal model preparation facilities, particularly relates to a kind of simple type animal model with spinal cord damnification crush injury preparation facilities.
Background technology
At present, animal model with spinal cord damnification has spinal cord impact damage model, spinal compression damage model, ischemia of spinal cord and reperfusion injury model, cutting and absorption type spinal cord injury model, hydrostatic profile spinal cord injury model, photochemical induction type spinal cord injury model, tractive property spinal cord injury model usually.Yet ideal spinal cord injury model should possess the condition of following 3 aspects: (1) clinical similarity: the spinal cord injury model of promptly making and clinical close, and as far as possible near human situation.Theoretically, make spinal column receive to cause injury after the effect of passivity violence, promptly so-called " closure spinal cord injury " can be simulated the impaired under external force and pathological change process thereafter of spinal cord, and is similar with the situation of human spinal cord injury.(2) Modulatory character: can adjust damage strength according to actual needs, copy the spinal cord injury model of different degree of injury.(3) operability is with repeatable, and each committed step of promptly spinal cord injury model being made objectifies, quantification, makes that it is with a high credibility, exploitativeness is strong, can reflect objective problem.At present, all there is certain limitation in the various method for preparinies of animal model with spinal cord damnification.So setting up ideal animal model with spinal cord damnification is the matter of utmost importance of carrying out spinal cord injury and repairing research.
Yet in the existing animal model with spinal cord damnification technology of preparing, there are not good reproducibility, strong operability, spinal cord crush injury preparation facilities that control is good as yet, are unfavorable for carrying out basic research.
Summary of the invention
The purpose of this utility model is to overcome the deficiency of prior art, and a kind of easy to operate, workable, good simple type animal model with spinal cord damnification crush injury preparation facilities of regulation and control performance is provided.
The purpose of this utility model realizes through following technical scheme: simple type animal model with spinal cord damnification crush injury preparation facilities; It comprises: each leg of extremity fixed support is fixed in location backing plate four edges; The extruding rotary screw passes the screw of location backing plate, and holding screw is fixed in extremity fixed support expansion link place.
Location backing plate self has a radian and can mate the rat back radian.
Around the extruded hole upper and lower, left and right of location backing plate an observation port is arranged respectively.
Location backing plate four edges are fixed at each leg top of extremity fixed support.
The support bracket fastened extremity of extremity can stretch up and down and can fix through holding screw.
Extruding rotary screw top diameter is 2 millimeters.
Extruding rotary screw screw rod has dark a sign for per 2 millimeters from rotary nut top to bottom.
Can find out through top narration, the utlity model has following advantage: structure is ingenious, simple, and is safe and practical, and observation port ability observation experiment animal (rat) spinal column around the backing plate extruded hole of location can conveniently be located the crush injury sections; And himself radian can mate laboratory animal (rat) back radian; The extremity fixed support is can easy on and off flexible and fix through holding screw, this performance can with different experiments animal (rat) body matched; The dark color at squeezing screw screw rod place indicates the distance that can show that rotation is advanced or retreated, and can show the spinal cord degree of extruding clearly.This device has not only been simplified the experimental implementation program, and workable, good reproducibility, control are high, are more convenient for carrying out the crush injury animal model preparation of spinal cord injury basic research.
Description of drawings
Fig. 1 is a kind of view of this utility model;
Fig. 2 is another view of this utility model;
Fig. 3 is location backing plate sketch map;
Fig. 4 is an extremity fixed support decomposing schematic representation;
Fig. 5 is the rotary screw sketch map;
Among the figure: 1-extremity fixed support, 2-locatees backing plate, and 3-pushes rotary screw, 4-holding screw, 5-extruding rotation extrusion screw inlet, 6-observation port.
The specific embodiment
Further describe the technical scheme of this utility model below in conjunction with accompanying drawing: as illustrated in fig. 1 and 2; Simple type animal model with spinal cord damnification crush injury preparation facilities; It comprises that extremity fixed support 1 each leg top is fixed in location backing plate 2 four edges; Extruding rotary screw 3 passes the screw of location backing plate 2, and holding screw 4 is fixed in extremity fixed support expansion link place.As shown in Figure 3, around the extruded hole observation port is arranged respectively in the backing plate 2 of location, as shown in Figure 4; Extremity fixed support 1 its extremity can freely stretch and can fix through holding screw, can be complementary with laboratory animal (rat) body height, and are as shown in Figure 5; Rotation extrusion screw 3 passes the extruding screw inlet of location backing plate 2; After being rotated down the arrival outlet, can pushing laboratory animal (rat) spinal column, and its spinal cord is carried out crush injury; The distance that rotation extrusion screw 1 promotes forward can be read from the black and white band of screw rod appearance, thereby calculates the degree of extruding spinal cord.
Though described the embodiment of this utility model in conjunction with accompanying drawing, the protection domain that those of ordinary skills do not need various distortion that the creativity work just can make or modification still to belong to this patent within the scope of the appended claims.
Claims (7)
1. simple type animal model with spinal cord damnification crush injury preparation facilities; It is characterized in that: it comprises that extremity fixed support (1) top is individually fixed in four edges of location backing plate (2); Extruding rotary screw (3) passes the extruded hole of location backing plate (2), and holding screw (4) is fixed in extremity fixed support expansion link place.
2. simple type animal model with spinal cord damnification crush injury preparation facilities according to claim 1 is characterized in that: location backing plate (2) self has a radian and can mate the rat back radian.
3. simple type animal model with spinal cord damnification crush injury preparation facilities according to claim 1 is characterized in that: an observation port is respectively arranged around the extruding screw upper and lower, left and right of location backing plate (2).
4. simple type animal model with spinal cord damnification crush injury preparation facilities according to claim 1 is characterized in that: location backing plate (2) four edges are fixed at each leg top of extremity fixed support (1).
5. simple type animal model with spinal cord damnification crush injury preparation facilities according to claim 1 is characterized in that: its extremity of extremity fixed support (1) can stretch up and down and can pass through holding screw (4) and fix.
6. simple type animal model with spinal cord damnification crush injury preparation facilities according to claim 1 is characterized in that: extruding rotary screw (3) top diameter is 2 millimeters.
7. simple type animal model with spinal cord damnification crush injury preparation facilities according to claim 1 is characterized in that: every mistake has dark a sign for 2 millimeters to extruding rotary screw (3) screw rod from rotary nut top to bottom.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011205277328U CN202376253U (en) | 2011-12-16 | 2011-12-16 | Simple crush injury preparation device of spinal cord injury animal model |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011205277328U CN202376253U (en) | 2011-12-16 | 2011-12-16 | Simple crush injury preparation device of spinal cord injury animal model |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202376253U true CN202376253U (en) | 2012-08-15 |
Family
ID=46624775
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011205277328U Expired - Fee Related CN202376253U (en) | 2011-12-16 | 2011-12-16 | Simple crush injury preparation device of spinal cord injury animal model |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202376253U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105919690A (en) * | 2016-05-25 | 2016-09-07 | 西安市红会医院 | Experimental device for animal CI-CS (crush injury-crush syndrome) |
| CN106912410A (en) * | 2017-03-13 | 2017-07-04 | 中国水产科学研究院南海水产研究所 | Combined type releasing device |
-
2011
- 2011-12-16 CN CN2011205277328U patent/CN202376253U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105919690A (en) * | 2016-05-25 | 2016-09-07 | 西安市红会医院 | Experimental device for animal CI-CS (crush injury-crush syndrome) |
| CN106912410A (en) * | 2017-03-13 | 2017-07-04 | 中国水产科学研究院南海水产研究所 | Combined type releasing device |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120815 Termination date: 20121216 |